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Design and Synthesis of Functionalized4-Aryl-Catechol Derivatives as New Anti-Inflammatory Agents with In Vivo Efficacy PART I

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo

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Synthesis and in vitro study of nitro- and methoxy-2-phenylbenzofurans as human monoamine oxidase inhibitors

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Plant extracts with anti-inflammatory properties—A new approach for characterization of their bioactive compounds and establishment of structure–antioxidant activity relationships

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Nonresolving Inflammation

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Structure-based design, synthesis and preliminary anti-inflammatory activity of bolinaquinone analogues

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Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes

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Recent advances in the search for novel 5-lipoxygenase inhibitors for the treatment of asthma

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Structural insight into the optimization of ethyl 5-hydroxybenzo[g]indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress inflammation

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Treatment of asthma with antileukotrienes: First line or last resort therapy?

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Therapeutic options for 5-lipoxygenase inhibitors

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Disodium cromoglycate inhibits asthma-like features induced by sphingosine-1-phosphate

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Synthesis of α-oxygenated ketones and substituted catechols via the rearrangement of N-enoxy- and N-aryloxyphthalimides

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Mono- and dinuclear cyclopalladates as catalysts for Suzuki–Miyaura cross-coupling reactions in predominantly aqueous media

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5-Lipoxygenase: regulation of expression and enzyme activity

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Use of a free radical method to evaluate antioxidant activity

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An expeditious synthesis of polyhydroxylated 2-arylbenzo[b]furans

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Conversion of Simple Cyclohexanones into Catechols

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Inhibition of 5-Lipoxygenase Product Synthesis by Natural Compounds of Plant Origin

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Leukotrienes

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Differential Metabolism of Exogenous and Endogenous Arachidonic Acid in Human Neutrophils

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Novel leukotriene biosynthesis inhibitors (2012-2016) as anti-inflammatory agents

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Implementing guidelines on reporting research using animals ( ARRIVE etc.): new requirements for publication in BJP

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Cysteinyl leukotrienes: multi‐functional mediators in allergic rhinitis

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Microsomal prostaglandin E synthase‐1 and 5‐lipoxygenase: potential drug targets in cancer

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Pharmacology of montelukast sodium (Singulair™), a potent and selective leukotriene D4receptor antagonist

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Nociceptin/orphanin FQ receptor activation decreases the airway hyperresponsiveness induced by allergen in sensitized mice

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Antioxidant and anti-inflammatory activities of selected medicinal plants and fungi containing phenolic and flavonoid compounds

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5-Lipoxygenase inhibitors: a review of recent developments and patents

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.bcp.2022.115385openalex-snapshot

Highly potent and selective 5-lipoxygenase inhibition by new, simple heteroaryl-substituted catechols for treatment of inflammation

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