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Side Chain-Modified Benzothiazinone Derivatives with Anti-Mycobacterial Activity

https://doi.org/10.2139/ssrn.4276522
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/emmm.201303575openalex-snapshot
Towards a new combination therapy for tuberculosis with next generation benzothiazinones
inferredcites →https://doi.org/10.1016/j.ejmech.2014.08.061openalex-snapshot
Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents
inferredcites →https://doi.org/10.1016/j.ejmech.2020.112773openalex-snapshot
Design, synthesis and evaluation of covalent inhibitors of DprE1 as antitubercular agents
inferredcites →https://doi.org/10.1016/j.trsl.2020.03.007openalex-snapshot
New tuberculosis drug targets, their inhibitors, and potential therapeutic impact
inferredcites →https://doi.org/10.1021/acs.jmedchem.0c00530openalex-snapshot
Amide Bond Bioisosteres: Strategies, Synthesis, and Successes
inferredcites →https://doi.org/10.1021/acs.jmedchem.1c01049openalex-snapshot
Structural and Activity Relationships of 6-Sulfonyl-8-Nitrobenzothiazinones as Antitubercular Agents
inferredcites →https://doi.org/10.1021/acs.jmedchem.5b00258openalex-snapshot
Applications of Fluorine in Medicinal Chemistry
inferredcites →https://doi.org/10.1021/acs.jmedchem.9b00912openalex-snapshot
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β- d -ribofuranose 2′-Oxidase
inferredcites →https://doi.org/10.1021/acsmedchemlett.1c00652openalex-snapshot
Development of 6-Methanesulfonyl-8-nitrobenzothiazinone Based Antitubercular Agents
inferredcites →https://doi.org/10.1021/acsmedchemlett.8b00634openalex-snapshot
Spirocyclic and Bicyclic 8-Nitrobenzothiazinones for Tuberculosis with Improved Physicochemical and Pharmacokinetic Properties
inferredcites →https://doi.org/10.1021/ja211042ropenalex-snapshot
Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β- d -ribofuranose 2′-Oxidase DprE1
inferredcites →https://doi.org/10.1021/ml500039gopenalex-snapshot
Design and Syntheses of Anti-Tuberculosis Agents Inspired by BTZ043 Using a Scaffold Simplification Strategy
inferredcites →https://doi.org/10.1038/s41598-018-31316-6openalex-snapshot
Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1
inferredcites →https://doi.org/10.1126/science.1171583openalex-snapshot
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis
inferredcites →https://doi.org/10.1126/scitranslmed.3004395openalex-snapshot
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis
inferredcites →https://doi.org/10.1128/aac.00681-18openalex-snapshot
Structure-Based Drug Design and Characterization of Sulfonyl-Piperazine Benzothiazinone Inhibitors of DprE1 from Mycobacterium tuberculosis
inferredcites →https://doi.org/10.2139/ssrn.4276522openalex-snapshot
Side Chain-Modified Benzothiazinone Derivatives with Anti-Mycobacterial Activity
inferredcites →https://doi.org/10.3390/app10072269openalex-snapshot
Development of Macozinone for TB treatment: An Update

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4622835openalex-extracted
inferred← citeshttps://doi.org/10.1002/slct.202404094openalex-snapshot
Recent Advancements in Benzothiazinones (BTZ) Analogs as DprE1 Inhibitor for Potent Antitubercular Therapeutics
inferred← citeshttps://doi.org/10.1016/j.ejmech.2023.115976openalex-snapshot
Benzothiozinone derivatives with anti-tubercular Activity−Further side chain investigation
inferred← citeshttps://doi.org/10.1016/j.tube.2025.102654openalex-snapshot
In vitro and in vivo activities of a novel benzothiopyranone candidate NTB-3119M against Mycobacterium tuberculosis
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5c03770openalex-snapshot
Discovery of Potent Benzoselenazinone-Based DprE1 Inhibitors: A Novel Selenium-Containing Scaffold with Superior Anti-TB Activity and Pharmacokinetic Properties
inferred← citeshttps://doi.org/10.3389/fphar.2026.1863735openalex-snapshot
Breaking the barrier: from biosynthetic inhibition to multidimensional modulation of the mycobacterial cell wall in tuberculosis therapy
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