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P2RX7 Gene Variants Associate with Altered Inflammasome Assembly and Reduced Pyroptosis in Chronic Nonbacterial Osteomyelitis (CNO)

https://doi.org/10.2139/ssrn.4498427
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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/1529-0131(200001)43:1<109::aid-anr14>3.0.co;2-3openalex-extracted
Evolution of chronic recurrent multifocal osteitis toward spondylarthropathy over the long term
inferredcites →https://doi.org/10.1007/978-1-62703-523-1_8openalex-extracted
ASC Speck Formation as a Readout for Inflammasome Activation
inferredcites →https://doi.org/10.1007/s00223-018-0495-0openalex-extracted
Chronic Non-bacterial Osteomyelitis: A Review
inferredcites →https://doi.org/10.1007/s11914-017-0405-9openalex-extracted
Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment
inferredcites →https://doi.org/10.1007/s11926-012-0239-5openalex-extracted
Current Understanding of the Pathogenesis and Management of Chronic Recurrent Multifocal Osteomyelitis
inferredcites →https://doi.org/10.1007/s11926-020-00928-1openalex-extracted
New Insights into Adult and Paediatric Chronic Non-bacterial Osteomyelitis CNO
inferredcites →https://doi.org/10.1016/j.ceca.2011.08.002openalex-extracted
Gain-of-function of P2X7 receptor gene variants in multiple sclerosis
inferredcites →https://doi.org/10.1016/j.clim.2017.11.011openalex-extracted
An optimized whole blood assay measuring expression and activity of NLRP3, NLRC4 and AIM2 inflammasomes
inferredcites →https://doi.org/10.1016/j.clim.2018.04.011openalex-extracted
CD14+ monocytes contribute to inflammation in chronic nonbacterial osteomyelitis (CNO) through increased NLRP3 inflammasome expression
inferredcites →https://doi.org/10.1016/j.coi.2011.07.005openalex-extracted
Cross-regulation between the IL-1β/IL-18 processing inflammasome and other inflammatory cytokines
inferredcites →https://doi.org/10.1038/ejhg.2011.245openalex-extracted
Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women
inferredcites →https://doi.org/10.1038/ni.2913openalex-extracted
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
inferredcites →https://doi.org/10.1038/nm.2710openalex-extracted
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity
inferredcites →https://doi.org/10.1038/s41421-020-0167-xopenalex-extracted
Inflammasome activation and regulation: toward a better understanding of complex mechanisms
inferredcites →https://doi.org/10.1056/nejmoa0807865openalex-extracted
An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist
inferredcites →https://doi.org/10.1056/nejmoa0809568openalex-extracted
An Autoinflammatory Disease Due to Homozygous Deletion of the IL1RN Locus
inferredcites →https://doi.org/10.1067/mpd.2002.126457openalex-extracted
Chronic recurrent multifocal osteomyelitis: Clinical outcomes after more than five years of follow-up
inferredcites →https://doi.org/10.1074/jbc.m209094200openalex-extracted
Dependence of Purinergic P2X Receptor Activity on Ectodomain Structure
inferredcites →https://doi.org/10.1084/jem.20161452openalex-extracted
Lipin-2 regulates NLRP3 inflammasome by affecting P2X7 receptor activation
inferredcites →https://doi.org/10.1093/hmg/11.8.961openalex-extracted
Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder
inferredcites →https://doi.org/10.1093/nar/29.1.308openalex-extracted
dbSNP: the NCBI database of genetic variation
inferredcites →https://doi.org/10.1093/rheumatology/kel190openalex-extracted
Classification of Non-Bacterial Osteitis: Retrospective study of clinical, immunological and genetic aspects in 89 patients
inferredcites →https://doi.org/10.1093/rheumatology/keq074openalex-extracted
Dysregulation of P2X7 receptor-inflammasome axis in SAPHO syndrome: successful treatment with anakinra
inferredcites →https://doi.org/10.1093/rheumatology/keq270openalex-extracted
Translational research network and patient registry for auto-inflammatory diseases
inferredcites →https://doi.org/10.1096/fj.09-150862openalex-extracted
Two haplotypes of the P2X 7 receptor containing the Ala‐348 to Thr polymorphism exhibit a gain‐of‐function effect and enhanced interleukin‐1β secretion
inferredcites →https://doi.org/10.1097/j.pain.0000000000001188openalex-extracted
Genetic variation in P2RX7 and pain tolerance
inferredcites →https://doi.org/10.1111/j.1399-0039.2011.01780.xopenalex-extracted
The human P2X7 receptor and its role in innate immunity
inferredcites →https://doi.org/10.1136/bmjopen-2017-017599openalex-extracted
Chronic non-bacterial osteitis from the patient perspective: a health services research through data collected from patient conferences
inferredcites →https://doi.org/10.1136/jmg.2005.030759openalex-extracted
Homozygous mutations in LPIN2 are responsible for the syndrome of chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anaemia (Majeed syndrome)
inferredcites →https://doi.org/10.1136/postgradmedj-2018-136036openalex-extracted
Genetic variation of rs7958311 inP2X7Rgene is associated with the susceptibility and disease activity of ankylosing spondylitis
inferredcites →https://doi.org/10.1152/physrev.00015.2002openalex-extracted
Molecular Physiology of P2X Receptors
inferredcites →https://doi.org/10.1182/blood-2017-10-810366openalex-extracted
Molecular genetic investigation, clinical features, and response to treatment in 21 patients with Schnitzler syndrome
inferredcites →https://doi.org/10.12659/msm.895763openalex-extracted
Association Between P2RX7 Gene and Hepatocellular Carcinoma Susceptibility: A Case-Control Study in a Chinese Han Population
inferredcites →https://doi.org/10.1371/journal.pone.0181685openalex-extracted
Single nucleotide polymorphisms associated with P2X7R function regulate the onset of gouty arthritis
inferredcites →https://doi.org/10.3389/fphar.2020.00096openalex-extracted
The P2X7 Receptor 489C>T Gain of Function Polymorphism Favors HHV-6A Infection and Associates With Female Idiopathic Infertility
inferredcites →https://doi.org/10.3389/fphar.2020.00793openalex-extracted
P2X7 in Cancer: From Molecular Mechanisms to Therapeutics
inferredcites →https://doi.org/10.3899/jrheum.160690openalex-extracted
Anakinra in a Cohort of Children with Chronic Nonbacterial Osteomyelitis

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inferred← citeshttps://doi.org/10.1016/b978-0-443-11980-4.00046-5openalex-snapshot
Autoinflammatory Bone Diseases
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