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Dual States of Bmi1-Expressing Intestinal Stem Cells Drive Epithelial Development

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LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation
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Cell Adhesion Molecule CD166/ALCAM Functions Within the Crypt to Orchestrate Murine Intestinal Stem Cell Homeostasis
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Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5- and Bmi1-Expressing Intestinal Cell Populations
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Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters
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Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells
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Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity
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Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells
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LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine
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LGR4 and LGR5 are R‐spondin receptors mediating Wnt/β‐catenin and Wnt/PCP signalling
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Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
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Restoration of p53 function leads to tumour regression in vivo
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A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
inferredcites →https://doi.org/10.1038/nature11965openalex-extracted
Intestinal label-retaining cells are secretory precursors expressing Lgr5
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Dimensionality reduction for visualizing single-cell data using UMAP
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Bmi1 is expressed in vivo in intestinal stem cells
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Mouse Label-Retaining Cells Are Molecularly and Functionally Distinct From Reserve Intestinal Stem Cells
inferredcites →https://doi.org/10.1073/pnas.1113890109openalex-extracted
Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells
inferredcites →https://doi.org/10.1073/pnas.1118857109openalex-extracted
The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations
inferredcites →https://doi.org/10.1073/pnas.242735899openalex-extracted
Molecular features of adult mouse small intestinal epithelial progenitors
inferredcites →https://doi.org/10.1073/pnas.91.22.10335openalex-extracted
Paneth cell differentiation in the developing intestine of normal and transgenic mice.
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Differential Hox Expression in Murine Embryonic Stem Cell Models of Normal and Malignant Hematopoiesis
inferredcites →https://doi.org/10.1089/scd.2015.0352openalex-extracted
Hox-Mediated Spatial and Temporal Coding of Stem Cells in Homeostasis and Neoplasia
inferredcites →https://doi.org/10.1093/bioinformatics/btw313openalex-extracted
Complex heatmaps reveal patterns and correlations in multidimensional genomic data
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The reactome pathway knowledgebase 2022
inferredcites →https://doi.org/10.1126/science.1180794openalex-extracted
Coexistence of Quiescent and Active Adult Stem Cells in Mammals
inferredcites →https://doi.org/10.1126/science.1213214openalex-extracted
Interconversion Between Intestinal Stem Cell Populations in Distinct Niches
inferredcites →https://doi.org/10.1126/science.aad0501openalex-extracted
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
inferredcites →https://doi.org/10.1126/science.aax0249openalex-extracted
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THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE
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inferredcites →https://doi.org/10.1172/jci200420800openalex-extracted
Bmi1, stem cells, and senescence regulation
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Talking to chromatin: post-translational modulation of polycomb group function
inferredcites →https://doi.org/10.1186/s13059-017-1382-0openalex-extracted
SCANPY: large-scale single-cell gene expression data analysis
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PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells
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Plasticity of Paneth cells and their ability to regulate intestinal stem cells
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Chromatin-association of the Polycomb group protein BMI1 is cell cycle-regulated and correlates with its phosphorylation status
inferredcites →https://doi.org/10.15252/embj.201694959openalex-extracted
Id2 controls specification of Lgr5+ intestinal stem cell progenitors during gut development
inferredcites →https://doi.org/10.1634/stemcells.2006-0229openalex-extracted
Bmi‐1‐Green Fluorescent Protein‐Knock‐In Mice Reveal the Dynamic Regulation of Bmi‐1 Expression in Normal and Leukemic Hematopoietic Cells
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Lineage commitment and maturation of epithelial cells in the gut
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Targeting the Hippo Pathway and Cancer through the TEAD Family of Transcription Factors
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