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A Drug-Drug Cocrystal Strategy To Regulation the Stability and Solubility: A Case Study of Temozolomide/Caffeic Acid

https://doi.org/10.2139/ssrn.4743802
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Crystal Engineering of Stable Temozolomide Cocrystals
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Insights into the spectral property and electronic structure of di-triphenylaniline-modified monothiophene, dithiophene and thienothiophene
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A comprehensive assessment on synthesis, growth, theoretical & optical properties of glycine zinc sulphate pentahydrate single crystal for third-order nonlinear optical applications
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Wavefunction and reactivity study of benzo[a]pyrene diol epoxide and its enantiomeric forms
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Theoretical and experimental cocrystal screening of temozolomide with a series of phenolic acids, promising cocrystal coformers
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Mechanism study on stability enhancement of adefovir dipivoxil by cocrystallization: Degradation kinetics and structure-stability correlation
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Co amorphous valsartan nifedipine system: Preparation, characterization, in vitro and in vivo evaluation
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Interaction between caffeic acid/caffeic acid phenethyl ester and micellar casein
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In vitro and in vivo antioxidant properties of chlorogenic acid and caffeic acid
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Physicochemical and mechanical properties of paracetamol cocrystal with 5-nitroisophthalic acid
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Quaternized chitosan/κ-carrageenan/caffeic acid–coated poly(3-hydroxybutyrate) fibrous materials: Preparation, antibacterial and antioxidant activity
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Receptor-mediated PLGA nanoparticles for glioblastoma multiforme treatment
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Delivery of liposome encapsulated temozolomide to brain tumour: Understanding the drug transport for optimisation
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Novel pharmaceutical cocrystal of lenalidomide with nicotinamide: Structural design, evaluation, and thermal phase transition study
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The dissolution behavior and apparent thermodynamic analysis of temozolomide in pure and mixed solvents
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Hydrolytic instability and low-loading levels of temozolomide to magnetic PLGA nanoparticles remain challenging against glioblastoma therapy
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Quantitative analysis of molecular surface based on improved Marching Tetrahedra algorithm
inferredcites →https://doi.org/10.1016/j.jphotobiol.2016.03.058openalex-extracted
Caffeic acid-coated multifunctional magnetic nanoparticles for the treatment and bimodal imaging of tumours
inferredcites →https://doi.org/10.1016/j.molliq.2023.122443openalex-extracted
Novel drug-drug salts of enoxacin with enhanced antibacterial activity: Insights from solubility and lipid-water partition coefficient
inferredcites →https://doi.org/10.1016/j.molstruc.2017.11.048openalex-extracted
Structural elucidation and physicochemical properties of an organic NLO crystal: 4-Nitrotoluene-2-sulphonic acid dihydrate
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The spectroscopic (FT-Raman, FT-IR, UV and NMR), molecular electrostatic potential, polarizability and hyperpolarizability, NBO and HOMO–LUMO analysis of monomeric and dimeric structures of 4-chloro-3,5-dinitrobenzoic acid
inferredcites →https://doi.org/10.1016/j.tice.2021.101705openalex-extracted
Anti-tumour potential and selectivity of caffeic acid phenethyl ester in osteosarcoma cells
inferredcites →https://doi.org/10.1021/acs.cgd.0c01153openalex-extracted
Temozolomide–Hesperetin Drug–Drug Cocrystal with Optimized Performance in Stability, Dissolution, and Tabletability
inferredcites →https://doi.org/10.1021/acs.cgd.0c01595openalex-extracted
Insight into the Formation of Cocrystals of Flavonoids and 4,4′-Vinylenedipyridine: Heteromolecular Hydrogen Bonds, Molar Ratio, and Structural Analysis
inferredcites →https://doi.org/10.1021/acs.cgd.8b00807openalex-extracted
Constructing Anti-Glioma Drug Combination with Optimized Properties through Cocrystallization
inferredcites →https://doi.org/10.1021/cg3002948openalex-extracted
Polymorphs, Salts, and Cocrystals: What’s in a Name?
inferredcites →https://doi.org/10.1021/cg400322topenalex-extracted
Temozolomide Cocrystals with Carboxamide Coformers
inferredcites →https://doi.org/10.1021/jm020936dopenalex-extracted
Antitumor Imidazotetrazines. 41. Conjugation of the Antitumor Agents Mitozolomide and Temozolomide to Peptides and Lexitropsins Bearing DNA Major and Minor Groove-Binding Structural Motifs
inferredcites →https://doi.org/10.1039/c2ce26528aopenalex-extracted
Temozolomide hydrochloride dihydrate
inferredcites →https://doi.org/10.1039/c8ce00707aopenalex-extracted
Pharmaceutical cocrystallization: an effective approach to modulate the physicochemical properties of solid-state drugs
inferredcites →https://doi.org/10.1080/08982104.2020.1748648openalex-extracted
Design of temozolomide-loaded proliposomes and lipid crystal nanoparticles with industrial feasible approaches: comparative assessment of drug loading, entrapment efficiency, and stability at plasma pH
inferredcites →https://doi.org/10.1158/1535-7163.mct-14-0113openalex-extracted
Evaluation of Novel Imidazotetrazine Analogues Designed to Overcome Temozolomide Resistance and Glioblastoma Regrowth
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Phase I and Pharmacokinetic Study of Temozolomide on a Daily-for-5-Days Schedule in Patients With Advanced Solid Malignancies
inferredcites →https://doi.org/10.1200/jco.2015.33.3_suppl.622openalex-extracted
Association of the apoptotic effect of the coffee deterpene kahweol on human colon cancer cell with the expression of heat shock proteins (HSPs).
inferredcites →https://doi.org/10.1200/jco.2018.36.15_suppl.e14035openalex-extracted
Randomized feasibility study of temozolomide chronotherapy for high grade glioma.
inferredcites →https://doi.org/10.14233/ajchem.2018.21348openalex-extracted
A Stability Indicating UPLC Method for Determination of Temozolomide and its Related Substances in Bulk and Finished Dosage Forms
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