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Polymorphs, Salts, and Cocrystals: What’s in a Name?
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/anie.199523111openalex-snapshot
Supramolecular Synthons in Crystal Engineering—A New Organic Synthesis
inferredcites →https://doi.org/10.1002/asia.201100638openalex-snapshot
Triclabendazole: An Intriguing Case of Co‐existence of Conformational and Tautomeric Polymorphism
inferredcites →https://doi.org/10.1002/jps.21280openalex-snapshot
The Co‐Crystal Approach to Improve the Exposure of a Water‐Insoluble Compound: AMG 517 Sorbic Acid Co‐Crystal Characterization and Pharmacokinetics
inferredcites →https://doi.org/10.1002/jps.2600580802openalex-snapshot
Pharmaceutical Applications of Polymorphism
inferredcites →https://doi.org/10.1007/s11095-006-9032-3openalex-snapshot
Use of a Glutaric Acid Cocrystal to Improve Oral Bioavailability of a Low Solubility API
inferredcites →https://doi.org/10.1016/j.drudis.2008.03.004openalex-snapshot
The role of cocrystals in pharmaceutical science
inferredcites →https://doi.org/10.1016/j.ejpb.2006.12.016openalex-snapshot
Performance comparison of a co-crystal of carbamazepine with marketed product
inferredcites →https://doi.org/10.1016/j.inoche.2007.10.024openalex-snapshot
Unprecedented sodium–oxygen clusters in the solid-state structure of trisodium hydrogentetravalproate monohydrate: A model for the physiological activity of the anticonvulsant drug Epilim®
inferredcites →https://doi.org/10.1016/s0169-409x(01)00098-9openalex-snapshot
Amorphous pharmaceutical solids: preparation, characterization and stabilization
inferredcites →https://doi.org/10.1021/cg049622copenalex-snapshot
The 2-Aminopyridinium-carboxylate Supramolecular Heterosynthon: A Robust Motif for Generation of Multiple-Component Crystals
inferredcites →https://doi.org/10.1021/cg0503346openalex-snapshot
Phase Solubility Diagrams of Cocrystals Are Explained by Solubility Product and Solution Complexation
inferredcites →https://doi.org/10.1021/cg060742popenalex-snapshot
Cocrystals of Piroxicam with Carboxylic Acids
inferredcites →https://doi.org/10.1021/cg060838jopenalex-snapshot
Diversity in Single- and Multiple-Component Crystals. The Search for and Prevalence of Polymorphs and Cocrystals
inferredcites →https://doi.org/10.1021/cg1010117openalex-snapshot
Fluconazole Cocrystals with Dicarboxylic Acids
inferredcites →https://doi.org/10.1021/cg200492wopenalex-snapshot
Solubility Advantage of Amorphous Drugs and Pharmaceutical Cocrystals
inferredcites →https://doi.org/10.1021/cg201510nopenalex-snapshot
Cocrystal Systems of Pharmaceutical Interest: 2010
inferredcites →https://doi.org/10.1021/cg701022eopenalex-snapshot
Polymorphism in Carbamazepine Cocrystals
inferredcites →https://doi.org/10.1021/cg900129fopenalex-snapshot
Pharmaceutical Cocrystals and Their Physicochemical Properties
inferredcites →https://doi.org/10.1021/cg900873topenalex-snapshot
A Survey of Cocrystals Reported Prior to 2000
inferredcites →https://doi.org/10.1021/cg901345uopenalex-snapshot
Structure−Stability Relationships in Cocrystal Hydrates: Does the Promiscuity of Water Make Crystalline Hydrates the Nemesis of Crystal Engineering?
inferredcites →https://doi.org/10.1021/j100165a007openalex-snapshot
Hydrogen bonds as design elements in organic chemistry
inferredcites →https://doi.org/10.1021/ja020751wopenalex-snapshot
Iterative High-Throughput Polymorphism Studies on Acetaminophen and an Experimentally Derived Structure for Form III
inferredcites →https://doi.org/10.1021/ja035776popenalex-snapshot
Crystal Engineering of Novel Cocrystals of a Triazole Drug with 1,4-Dicarboxylic Acids
inferredcites →https://doi.org/10.1021/ja048114oopenalex-snapshot
Crystal Engineering Approach To Forming Cocrystals of Amine Hydrochlorides with Organic Acids. Molecular Complexes of Fluoxetine Hydrochloride with Benzoic, Succinic, and Fumaric Acids
inferredcites →https://doi.org/10.1021/ja203002wopenalex-snapshot
2:1 Cocrystals of Homochiral and Achiral Amino Acid Zwitterions with Li+ Salts: Water-Stable Zeolitic and Diamondoid Metal–Organic Materials
inferredcites →https://doi.org/10.1021/js9601896openalex-snapshot
Characteristics and Significance of the Amorphous State in Pharmaceutical Systems
inferredcites →https://doi.org/10.1021/mp060126oopenalex-snapshot
Cocrystal or Salt: Does It Really Matter?
inferredcites →https://doi.org/10.1021/mp0601345openalex-snapshot
The Salt−Cocrystal Continuum: The Influence of Crystal Structure on Ionization State
inferredcites →https://doi.org/10.1021/mp070001zopenalex-snapshot
An Overview of Pharmaceutical Cocrystals as Intellectual Property
inferredcites →https://doi.org/10.1021/mp0700054openalex-snapshot
Screening for Pharmaceutical Cocrystal Hydrates via Neat and Liquid-Assisted Grinding
inferredcites →https://doi.org/10.1039/b208574gopenalex-snapshot
Crystal engineering of the composition of pharmaceutical phases
inferredcites →https://doi.org/10.1039/b402150aopenalex-snapshot
Crystal engineering of the composition of pharmaceutical phases. Do pharmaceutical co-crystals represent a new path to improved medicines?
inferredcites →https://doi.org/10.1039/b505883jopenalex-snapshot
Building co-crystals with molecular sense and supramolecular sensibility
inferredcites →https://doi.org/10.1039/b800293bopenalex-snapshot
Ternary and quaternary co-crystals of 1,3-cis,5-cis-cyclohexanetricarboxylic acid and 4,4′-bipyridines
inferredcites →https://doi.org/10.1039/c0cc02701dopenalex-snapshot
From unexpected reactions to a new family of ionic co-crystals: the case of barbituric acid with alkali bromides and caesium iodide
inferredcites →https://doi.org/10.1039/p29930002209openalex-snapshot
Molecular recognition involving an interplay of O–H⋯O, C–H⋯O and π⋯π interactions. The anomalous crystal structure of the 1 : 1 complex 3,5-dinitrobenzoic acid–4-(N,N-dimethylamino)benzoic acid
inferredcites →https://doi.org/10.1088/1126-6708/2003/01/036openalex-snapshot
Superstring interactions in a pp-wave background II
inferredcites →https://doi.org/10.1111/j.2042-7158.2010.01133.xopenalex-snapshot
Benefits of cocrystallisation in pharmaceutical materials science: an update
inferredcites →https://doi.org/10.1557/mrs2006.206openalex-snapshot
Pharmaceutical Cocrystals: An Emerging Approach to Physical Property Enhancement
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Fundamentals of Industrial Crystallization
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An industrial perspective on co-crystals: Screening, identification and development of the less utilised solid form in drug discovery and development
inferred← citeshttps://doi.org/10.1016/bs.podrm.2018.11.004openalex-snapshot
Cocrystal Systems of Pharmaceutical Interest: 2012–2014
inferred← citeshttps://doi.org/10.1016/j.aac.2022.09.001openalex-snapshot
Crystal engineering in the development of improved pesticide products
inferred← citeshttps://doi.org/10.1016/j.aca.2026.346278openalex-snapshot
Analytical strategies for stage-appropriate solubility determination of drug candidates in the pharmaceutical industry: A review
inferred← citeshttps://doi.org/10.1016/j.addr.2016.04.022openalex-snapshot
Cocrystals to facilitate delivery of poorly soluble compounds beyond-rule-of-5
inferred← citeshttps://doi.org/10.1016/j.addr.2016.12.001openalex-snapshot
Recent progress of structural study of polymorphic pharmaceutical drugs
inferred← citeshttps://doi.org/10.1016/j.addr.2017.03.002openalex-snapshot
Pharmaceutical solvates, hydrates and amorphous forms: A special emphasis on cocrystals
inferred← citeshttps://doi.org/10.1016/j.addr.2017.07.001openalex-snapshot
Pharmaceutical aspects of salt and cocrystal forms of APIs and characterization challenges
inferred← citeshttps://doi.org/10.1016/j.addr.2017.07.008openalex-snapshot
Advanced methodologies for cocrystal synthesis
inferred← citeshttps://doi.org/10.1016/j.addr.2017.08.006openalex-snapshot
Experimental cocrystal screening and solution based scale-up cocrystallization methods
inferred← citeshttps://doi.org/10.1016/j.addr.2017.09.014openalex-snapshot
Pharmaceutical cocrystals, salts and polymorphs: Advanced characterization techniques
inferred← citeshttps://doi.org/10.1016/j.addr.2018.07.010openalex-snapshot
Supercritical carbon dioxide-based technologies for the production of drug nanoparticles/nanocrystals – A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.ajps.2020.06.004openalex-snapshot
Drug-drug cocrystals: Opportunities and challenges
inferred← citeshttps://doi.org/10.1016/j.apsb.2025.12.003openalex-snapshot
Crystal engineering for poorly water-soluble drugs: From design to applications
inferred← citeshttps://doi.org/10.1016/j.ccr.2023.215095openalex-snapshot
Cocrystals for photochemical solid-state reactions: An account on crystal engineering perspective
inferred← citeshttps://doi.org/10.1016/j.ccr.2024.215994openalex-snapshot
Unravelling the potential of sigma hole-assisted co-crystallization: Highlighting recent developments
inferred← citeshttps://doi.org/10.1016/j.ccr.2025.217284openalex-snapshot
NMR spectroscopy studies of hydrogen bonding
inferred← citeshttps://doi.org/10.1016/j.ccr.2026.217610openalex-snapshot
Solid-state NMR characterization of weak interactions in molecular crystals
inferred← citeshttps://doi.org/10.1016/j.cdc.2023.101100openalex-snapshot
Crystal structure, intermolecular interactions, charge density distribution and ADME properties of 2-Amino-4-methylpyridinium (oxalate) 0.5: An experimental and theoretical study
inferred← citeshttps://doi.org/10.1016/j.cdc.2023.101102openalex-snapshot
A 1:1 cocrystal of 4-oxo-4-(pyridin-2-ylamino)butanoic acid and benzoic acid: Synthesis, characterization, structural and energy framework analysis
inferred← citeshttps://doi.org/10.1016/j.cej.2013.04.002openalex-snapshot
Stabilization and spheroidization of ammonium nitrate: Co-crystallization with crown ethers and spherical crystallization by solvent screening
inferred← citeshttps://doi.org/10.1016/j.cej.2018.06.051openalex-snapshot
Developments and challenges in the manufacturing, characterization and scale-up of energetic nanomaterials – A review
inferred← citeshttps://doi.org/10.1016/j.cej.2022.136403openalex-snapshot
A sulfone-based crystalline organic electrolyte for 5 V solid-state potassium batteries
inferred← citeshttps://doi.org/10.1016/j.cej.2024.158949openalex-snapshot
Breaking separation bottleneck in sucralose production: Clarifying the obscure mechanism and pre-embedding second solvents for highly selective separation of chlorinated product
inferred← citeshttps://doi.org/10.1016/j.cep.2024.110108openalex-snapshot
Intensified solid-state transformation during anti-solvent cocrystallization in flow
inferred← citeshttps://doi.org/10.1016/j.ces.2016.06.005openalex-snapshot
PAT-based design of agrochemical co-crystallization processes: A case-study for the selective crystallization of 1:1 and 3:2 co-crystals of p-toluenesulfonamide/triphenylphosphine oxide
inferred← citeshttps://doi.org/10.1016/j.ces.2026.124117openalex-snapshot
Explainable machine learning prediction model and experimental verification of pharmaceutical multicomponent crystals
inferred← citeshttps://doi.org/10.1016/j.chemolab.2025.105318openalex-snapshot
Advanced feature analysis for enhancing cocrystal prediction
inferred← citeshttps://doi.org/10.1016/j.cherd.2022.07.012openalex-snapshot
Development of sulfamethoxazole-succinimide cocrystal by mechanochemical cocrystallization – An insight into spectroscopic, electronic, chemical conformation and physicochemical properties
inferred← citeshttps://doi.org/10.1016/j.comptc.2022.113791openalex-snapshot
Topological and DFT studies of 8-hydroxyquinoline derivative and its copper complex having supramolecular interactions network
inferred← citeshttps://doi.org/10.1016/j.cplett.2024.141772openalex-snapshot
Thiabendazole: Fumaric acid as a case study on the salt cocrystal continuum: A local vibrational mode perspective
inferred← citeshttps://doi.org/10.1016/j.drudis.2016.02.001openalex-snapshot
Multidrug co-crystals: towards the development of effective therapeutic hybrids
inferred← citeshttps://doi.org/10.1016/j.drudis.2017.01.010openalex-snapshot
Can pharmaceutical co-crystals provide an opportunity to modify the biological properties of drugs?
inferred← citeshttps://doi.org/10.1016/j.drudis.2018.11.023openalex-snapshot
Pharmaceutical cocrystals: from serendipity to design to application
inferred← citeshttps://doi.org/10.1016/j.drudis.2020.11.016openalex-snapshot
Recent developments in pharmaceutical salts: FDA approvals from 2015 to 2019
inferred← citeshttps://doi.org/10.1016/j.drudis.2023.103494openalex-snapshot
Importance of tautomerism in drugs
inferred← citeshttps://doi.org/10.1016/j.ejmech.2013.11.045openalex-snapshot
Pharmaceutical salts and cocrystals involving amino acids: A brief structural overview of the state-of-art
inferred← citeshttps://doi.org/10.1016/j.ejpb.2019.01.018openalex-snapshot
Screening a trace amount of pharmaceutical cocrystals by using an enhanced nano-spot method
inferred← citeshttps://doi.org/10.1016/j.ejpb.2020.01.021openalex-snapshot
Cocrystal formulations: A case study of topical formulations consisting of ferulic acid cocrystals
inferred← citeshttps://doi.org/10.1016/j.ejpb.2024.114463openalex-snapshot
Designing type V deep eutectic solvents with antimalarial pharmaceutical ingredients
inferred← citeshttps://doi.org/10.1016/j.ejpb.2026.115075openalex-snapshot
Improving oral bioavailability and tabletability of celecoxib by preparing its three cocrystals
inferred← citeshttps://doi.org/10.1016/j.ejpb.2026.115101openalex-snapshot
The role of pharmaceutical formulation development in clinical trials of new medicinal products
inferred← citeshttps://doi.org/10.1016/j.ejpb.2026.115217openalex-snapshot
Towards macrophage-oriented Antituberculosis therapy: nanohydrogel and liposomal delivery of rifampicin–berberine Co-nanocrystals for enhanced intracellular Antituberculosis activity
inferred← citeshttps://doi.org/10.1016/j.ejps.2015.12.018openalex-snapshot
Pharmaceutical excipients — quality, regulatory and biopharmaceutical considerations
inferred← citeshttps://doi.org/10.1016/j.ejps.2016.02.010openalex-snapshot
Propensity of salicylamide and ethenzamide cocrystallization with aromatic carboxylic acids
inferred← citeshttps://doi.org/10.1016/j.ejps.2016.09.025openalex-snapshot
Interrelation of the dissolution behavior and solid-state features of acetazolamide cocrystals
inferred← citeshttps://doi.org/10.1016/j.ejps.2016.12.016openalex-snapshot
Drug-drug cocrystals of antituberculous 4-aminosalicylic acid: Screening, crystal structures, thermochemical and solubility studies
inferred← citeshttps://doi.org/10.1016/j.ejps.2017.04.008openalex-snapshot
Dapagliflozin-citric acid cocrystal showing better solid state properties than dapagliflozin
inferred← citeshttps://doi.org/10.1016/j.ejps.2017.09.020openalex-snapshot
Phenazopyridine-phthalimide nano-cocrystal: Release rate and oral bioavailability enhancement
inferred← citeshttps://doi.org/10.1016/j.ejps.2018.07.038openalex-snapshot
Cocrystallization as a novel approach to enhance the transdermal administration of meloxicam
inferred← citeshttps://doi.org/10.1016/j.ejps.2019.104981openalex-snapshot
Continuous, simultaneous cocrystallization and formulation of Theophylline and 4-Aminobenzoic acid pharmaceutical cocrystals using twin screw melt granulation
inferred← citeshttps://doi.org/10.1016/j.ejps.2021.106043openalex-snapshot
UNGAP best practice for improving solubility data quality of orally administered drugs
inferred← citeshttps://doi.org/10.1016/j.ejps.2022.106241openalex-snapshot
Azilsartan-nicotinamide cocrystal: Preparation, characterization and in vitro / vivo evaluation
inferred← citeshttps://doi.org/10.1016/j.ejps.2023.106530openalex-snapshot
Preparation of pazopanib-fumarate disodium glycyrrhizinate nanocrystalline micelles by liquid-assisted ball milling
inferred← citeshttps://doi.org/10.1016/j.ejps.2026.107499openalex-snapshot
A fast method to predict solubility of neutral co-crystals in aqueous media
inferred← citeshttps://doi.org/10.1016/j.eng.2017.03.022openalex-snapshot
Recent Developments in the Crystallization Process: Toward the Pharmaceutical Industry
inferred← citeshttps://doi.org/10.1016/j.enmf.2021.01.004openalex-snapshot
Solubility behaviour of CL-20 and HMX in organic solvents and solvates of CL-20
inferred← citeshttps://doi.org/10.1016/j.ensm.2021.04.031openalex-snapshot
A crystalline organic electrolyte for safe, room-temperature operable all-solid-state sodium batteries
inferred← citeshttps://doi.org/10.1016/j.eurpolymj.2024.113247openalex-snapshot
Aromatic nitrile resins with improved processability and thermal properties prepared by collaborative design of structure and blending strategy
inferred← citeshttps://doi.org/10.1016/j.fluid.2013.11.024openalex-snapshot
Solubility of carbamazepine, nicotinamide and carbamazepine–nicotinamide cocrystal in ethanol–water mixtures
inferred← citeshttps://doi.org/10.1016/j.fluid.2016.02.047openalex-snapshot
Solid–liquid phase equilibrium and ternary phase diagrams of ethenzamide-saccharin cocrystals in different solvents
inferred← citeshttps://doi.org/10.1016/j.foodchem.2020.126884openalex-snapshot
Exploring the solid-state phases and thermodynamics of calcium l-lactate
inferred← citeshttps://doi.org/10.1016/j.heliyon.2019.e02291openalex-snapshot
Synthesis and characterization of a (+)-catechin and L-(+)-ascorbic acid cocrystal as a new functional ingredient for tea drinks
inferred← citeshttps://doi.org/10.1016/j.ica.2012.09.036openalex-snapshot
Polymorphs or solvates? Coordination of 3,5-dihydroxybenzoate to copper and zinc metal centers
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2012.10.043openalex-snapshot
Pharmaceutical cocrystals and poorly soluble drugs
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2012.11.028openalex-snapshot
Use of pharmaceutical salts and cocrystals to address the issue of poor solubility
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2014.04.025openalex-snapshot
Investigation of the phase transitions occurring during and after the dehydration of xylazine hydrochloride monohydrate
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2018.06.024openalex-snapshot
Pharmaceutical cocrystallization techniques. Advances and challenges
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2019.06.031openalex-snapshot
Impact of polymeric excipient on cocrystal formation via hot-melt extrusion and subsequent downstream processing
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2020.119600openalex-snapshot
Polymorphs and pharmacokinetics of an antipsychotic drug candidate
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2020.120034openalex-snapshot
Recent advances in low-frequency Raman spectroscopy for pharmaceutical applications
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.120514openalex-snapshot
Understanding solid-state processing of pharmaceutical cocrystals via milling: Role of tablet excipients
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.120555openalex-snapshot
In-line Raman spectroscopy and chemometrics for monitoring cocrystallisation using hot melt extrusion
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.120669openalex-snapshot
Formulation of ionic liquid APIs via spray drying processes to enable conversion into single and two-phase solid forms
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.121196openalex-snapshot
Use of Atomic Force Microscopy (AFM) to monitor surface crystallization in caffeine-oxalic acid (CAFOXA) cocrystal compacts
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2022.121460openalex-snapshot
Improving the dissolution behaviors and bioavailability of abiraterone acetate via multicomponent crystal forms
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2022.121798openalex-snapshot
Solid-state and particle size control of pharmaceutical cocrystals using atomization-based techniques
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2022.122461openalex-snapshot
Rucaparib cocrystal: Improved solubility and bioavailability over camsylate
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2023.123053openalex-snapshot
Crystalline and amorphous famotidine malate as pathways to prevent polymorphic transformation with improved dissolution
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2023.123555openalex-snapshot
Molecular complexes of drug combinations: A review of cocrystals, salts, coamorphous systems and amorphous solid dispersions
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2024.123793openalex-snapshot
Development of direct compression Acetazolamide tablet with improved bioavailability in healthy human volunteers enabled by cocrystallization with p-Aminobenzoic acid
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2024.125075openalex-snapshot
Exploring the hydrate landscape using data mining on the Cambridge structural database (CSD)
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2025.126016openalex-snapshot
Novel multi-nozzle spray coating technology for the continuous production and isolation of drug nanoparticles
inferred← citeshttps://doi.org/10.1016/j.jconrel.2022.06.003openalex-snapshot
Unlocking the potential of drug-drug cocrystals – A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.jconrel.2024.03.034openalex-snapshot
An analysis of multidrug multicomponent crystals as tools for drug development
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