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The Novel Tfeb Agonist Desloratadine Promotes Lipid Clearance by Activating the Autophagy-Lysosome Pathway
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/hep.28820openalex-extracted
Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice
inferredcites →https://doi.org/10.1016/j.apsb.2021.12.012openalex-extracted
Nuciferine protects against high-fat diet-induced hepatic steatosis and insulin resistance via activating TFEB-mediated autophagy–lysosomal pathway
inferredcites →https://doi.org/10.1016/j.bcp.2018.11.016openalex-extracted
Clomiphene citrate induces nuclear translocation of the TFEB transcription factor and triggers apoptosis by enhancing lysosomal membrane permeabilization
inferredcites →https://doi.org/10.1016/j.cell.2021.04.015openalex-extracted
Mechanisms and disease consequences of nonalcoholic fatty liver disease
inferredcites →https://doi.org/10.1016/j.mam.2021.100973openalex-extracted
Autophagy in liver diseases: A review
inferredcites →https://doi.org/10.1016/j.molcel.2021.03.009openalex-extracted
mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
inferredcites →https://doi.org/10.1016/j.phrs.2021.105484openalex-extracted
Epigenetics in NAFLD/NASH: Targets and therapy
inferredcites →https://doi.org/10.1016/s0022-2275(20)31157-3openalex-extracted
Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span
inferredcites →https://doi.org/10.1038/nature07976openalex-extracted
Autophagy regulates lipid metabolism
inferredcites →https://doi.org/10.1038/nrgastro.2013.41openalex-extracted
Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
inferredcites →https://doi.org/10.1038/nrgastro.2016.185openalex-extracted
Autophagy in the liver: functions in health and disease
inferredcites →https://doi.org/10.1038/nrm.2017.76openalex-extracted
Cytosolic lipolysis and lipophagy: two sides of the same coin
inferredcites →https://doi.org/10.1038/s41467-017-02332-3openalex-extracted
Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan
inferredcites →https://doi.org/10.1038/s41467-018-03939-wopenalex-extracted
A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes
inferredcites →https://doi.org/10.1038/s42255-021-00493-6openalex-extracted
Lipolysis: cellular mechanisms for lipid mobilization from fat stores
inferredcites →https://doi.org/10.1080/15548627.2018.1490850openalex-extracted
Dynamic MTORC1-TFEB feedback signaling regulates hepatic autophagy, steatosis and liver injury in long-term nutrient oversupply
inferredcites →https://doi.org/10.1080/15548627.2023.2254191openalex-extracted
Dysfunction of autophagy in high-fat diet-induced non-alcoholic fatty liver disease
inferredcites →https://doi.org/10.1101/gad.274142.115openalex-extracted
AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes
inferredcites →https://doi.org/10.1126/science.1174447openalex-extracted
A Gene Network Regulating Lysosomal Biogenesis and Function
inferredcites →https://doi.org/10.1126/science.1204592openalex-extracted
TFEB Links Autophagy to Lysosomal Biogenesis
inferredcites →https://doi.org/10.1126/science.abj5559openalex-extracted
Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1
inferredcites →https://doi.org/10.1126/scisignal.2002790openalex-extracted
The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
inferredcites →https://doi.org/10.1146/annurev-nutr-071813-105336openalex-extracted
Autophagy and Lipid Droplets in the Liver
inferredcites →https://doi.org/10.2165/11530930-000000000-00000openalex-extracted
Safety and Efficacy of Desloratadine in Subjects with Seasonal Allergic Rhinitis or Chronic Urticaria
inferredcites →https://doi.org/10.3389/fgene.2022.1013266openalex-extracted
Lysosomal acid lipase deficiency: A rare inherited dyslipidemia but potential ubiquitous factor in the development of atherosclerosis and fatty liver disease
inferredcites →https://doi.org/10.4161/auto.19653openalex-extracted
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
inferredcites →https://doi.org/10.7150/thno.49860openalex-extracted
Selective autophagy of intracellular organelles: Recent research advances
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