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Histone Lactylation-Mediated PRRC2A Overexpression Promotes Colorectal Cancer Progression in M6A Modification-Dependent Manner

https://doi.org/10.2139/ssrn.4750448
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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s00018-010-0329-3openalex-extracted
Regulation of Lrp6 phosphorylation
inferredcites →https://doi.org/10.1007/s11596-019-2050-2openalex-extracted
Lactate Promotes Cancer Stem-like Property of Oral Sequamous Cell Carcinoma
inferredcites →https://doi.org/10.1016/j.bbrc.2020.08.066openalex-extracted
The Daple-CK1ε complex regulates Dvl2 phosphorylation and canonical Wnt signaling
inferredcites →https://doi.org/10.1016/j.canlet.2020.08.044openalex-extracted
Differentiated cancer cell-originated lactate promotes the self-renewal of cancer stem cells in patient-derived colorectal cancer organoids
inferredcites →https://doi.org/10.1016/j.ccell.2020.02.004openalex-extracted
m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer
inferredcites →https://doi.org/10.1016/j.molcel.2021.01.006openalex-extracted
The phosphorylation switch that regulates ticking of the circadian clock
inferredcites →https://doi.org/10.1016/j.tig.2021.09.009openalex-extracted
Histone lactylation: epigenetic mark of glycolytic switch
inferredcites →https://doi.org/10.1016/s0140-6736(13)61649-9openalex-extracted
Colorectal cancer
inferredcites →https://doi.org/10.1017/erm.2022.42openalex-extracted
Lactate, histone lactylation and cancer hallmarks
inferredcites →https://doi.org/10.1038/nature11112openalex-extracted
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
inferredcites →https://doi.org/10.1038/nature11706openalex-extracted
How cancer metabolism is tuned for proliferation and vulnerable to disruption
inferredcites →https://doi.org/10.1038/nature13490openalex-extracted
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
inferredcites →https://doi.org/10.1038/nrc.2016.77openalex-extracted
Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
inferredcites →https://doi.org/10.1038/onc.2016.209openalex-extracted
Activation of CK1ɛ by PP2A/PR61ɛ is required for the initiation of Wnt signaling
inferredcites →https://doi.org/10.1038/s12276-021-00681-0openalex-extracted
Roles of circadian clocks in cancer pathogenesis and treatment
inferredcites →https://doi.org/10.1038/s41422-018-0040-8openalex-extracted
Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism
inferredcites →https://doi.org/10.1038/s41422-018-0113-8openalex-extracted
A novel m6A reader Prrc2a controls oligodendroglial specification and myelination
inferredcites →https://doi.org/10.1038/s41467-021-22544-yopenalex-extracted
Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ
inferredcites →https://doi.org/10.1038/s41467-022-32521-8openalex-extracted
Lactate increases stemness of CD8 + T cells to augment anti-tumor immunity
inferredcites →https://doi.org/10.1038/s41568-020-0253-2openalex-extracted
Role of RNA modifications in cancer
inferredcites →https://doi.org/10.1038/s41577-020-0406-2openalex-extracted
Lactate modulation of immune responses in inflammatory versus tumour microenvironments
inferredcites →https://doi.org/10.1038/s41586-019-1678-1openalex-extracted
Metabolic regulation of gene expression by histone lactylation
inferredcites →https://doi.org/10.1038/s42255-020-0243-4openalex-extracted
Lactate: the ugly duckling of energy metabolism
inferredcites →https://doi.org/10.1053/j.gastro.2021.12.269openalex-extracted
N6-Methyladenosine Reader YTHDF1 Promotes ARHGEF2 Translation and RhoA Signaling in Colorectal Cancer
inferredcites →https://doi.org/10.1101/gad.1843810openalex-extracted
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF β-TRCP
inferredcites →https://doi.org/10.1126/science.1160809openalex-extracted
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
inferredcites →https://doi.org/10.1158/0008-5472.can-18-2965openalex-extracted
The Critical Role of RNA m6A Methylation in Cancer
inferredcites →https://doi.org/10.1158/2159-8290.cd-20-0331openalex-extracted
The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem Cells
inferredcites →https://doi.org/10.1186/s13059-022-02775-yopenalex-extracted
H3K18 lactylation marks tissue-specific active enhancers
inferredcites →https://doi.org/10.2147/jhc.s337111openalex-extracted
PRRC2A Promotes Hepatocellular Carcinoma Progression and Associates with Immune Infiltration
inferredcites →https://doi.org/10.3389/fonc.2021.647559openalex-extracted
Lactate Modulates Cellular Metabolism Through Histone Lactylation-Mediated Gene Expression in Non-Small Cell Lung Cancer
inferredcites →https://doi.org/10.3389/fonc.2022.844477openalex-extracted
The CK1δ/ϵ-Tip60 Axis Enhances Wnt/β-Catenin Signaling via Regulating β-Catenin Acetylation in Colon Cancer
inferredcites →https://doi.org/10.3390/nu9060572openalex-extracted
(−)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway
inferredcites →https://doi.org/10.7150/ijbs.40960openalex-extracted
IC261, a specific inhibitor of CK1δ/ε, promotes aerobic glycolysis through p53-dependent mechanisms in colon cancer
inferredcites →https://doi.org/10.7150/jca.62211openalex-extracted
LATS1 exerts tumor suppressor functions via targeting Gli1 in colorectal cancer
inferredcites →https://doi.org/10.7150/thno.53901openalex-extracted
The CK1δ/ε-AES axis regulates tumorigenesis and metastasis in colorectal cancer
inferredcites →https://doi.org/10.7150/thno.76619openalex-extracted
Identifying the E2F3-MEX3A-KLF4 signaling axis that sustains cancer cells in undifferentiated and proliferative state
inferredcites →https://doi.org/10.7554/elife.29538openalex-extracted
Stress responsive miR-31 is a major modulator of mouse intestinal stem cells during regeneration and tumorigenesis
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