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Astragaloside IV Exhibited Antidiabetic Effects by Improving Glucose Metabolism, Repairing Damaged Gut Barrier and Regulating Intestinal Microbiota

https://doi.org/10.2139/ssrn.4764792
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Clinical efficacies, underlying mechanisms and molecular targets of Chinese medicines for diabetic nephropathy treatment and management
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Therapeutic effects of Chinese herbal medicines and their extracts on diabetes
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Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life
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The Prevotella copri Complex Comprises Four Distinct Clades Underrepresented in Westernized Populations
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Microbiota-Produced Succinate Improves Glucose Homeostasis via Intestinal Gluconeogenesis
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Gut Microbiome Fermentation Determines the Efficacy of Exercise for Diabetes Prevention
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Astragaloside IV attenuates sepsis-induced intestinal barrier dysfunction via suppressing RhoA/NLRP3 inflammasome signaling
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Next generation probiotics in disease amelioration
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Puerariae Lobatae Radix with chuanxiong Rhizoma for treatment of cerebral ischemic stroke by remodeling gut microbiota to regulate the brain–gut barriers
inferredcites →https://doi.org/10.1016/j.metabol.2021.154712openalex-extracted
Role of the gut microbiota in type 2 diabetes and related diseases
inferredcites →https://doi.org/10.1016/j.phrs.2019.02.024openalex-extracted
Gut microbiota, a new frontier to understand traditional Chinese medicines
inferredcites →https://doi.org/10.1016/j.phrs.2020.104831openalex-extracted
Astragaloside IV acts through multi-scale mechanisms to effectively reduce diabetic nephropathy
inferredcites →https://doi.org/10.1016/j.phymed.2022.154171openalex-extracted
Astragaloside IV ameliorates pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension by restraining the T follicular helper cell response and expanding T follicular regulatory cell response
inferredcites →https://doi.org/10.1038/ctg.2016.54openalex-extracted
Human Intestinal Barrier Function in Health and Disease
inferredcites →https://doi.org/10.1038/nature11450openalex-extracted
A metagenome-wide association study of gut microbiota in type 2 diabetes
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Analyses of gut microbiota and plasma bile acids enable stratification of patients for antidiabetic treatment
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Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes
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Berberine is an insulin secretagogue targeting the KCNH6 potassium channel
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A propolis-derived small molecule ameliorates metabolic syndrome in obese mice by targeting the CREB/CRTC2 transcriptional complex
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The intestinal microbiota fuelling metabolic inflammation
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Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals
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Astragaloside IV ameliorates 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis implicating regulation of energy metabolism
inferredcites →https://doi.org/10.1093/bioinformatics/btn025openalex-extracted
SOAP: short oligonucleotide alignment program
inferredcites →https://doi.org/10.1093/bioinformatics/btp324openalex-extracted
Fast and accurate short read alignment with Burrows–Wheeler transform
inferredcites →https://doi.org/10.1093/bioinformatics/bts565openalex-extracted
CD-HIT: accelerated for clustering the next-generation sequencing data
inferredcites →https://doi.org/10.1093/bioinformatics/btv033openalex-extracted
MEGAHIT: an ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph
inferredcites →https://doi.org/10.1093/bioinformatics/bty560openalex-extracted
fastp: an ultra-fast all-in-one FASTQ preprocessor
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MetaGene: prokaryotic gene finding from environmental genome shotgun sequences
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Reclassification of the Clostridium clostridioforme and Clostridium sphenoides clades as Enterocloster gen. nov. and Lacrimispora gen. nov., including reclassification of 15 taxa
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Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes
inferredcites →https://doi.org/10.1126/science.aar3318openalex-extracted
Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection
inferredcites →https://doi.org/10.1126/science.abp9960openalex-extracted
The microbiome and gut homeostasis
inferredcites →https://doi.org/10.1155/2021/1481236openalex-extracted
Molecular Mechanism of Astragaloside IV in Improving Endothelial Dysfunction of Cardiovascular Diseases Mediated by Oxidative Stress
inferredcites →https://doi.org/10.1186/s13046-018-0878-0openalex-extracted
Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling
inferredcites →https://doi.org/10.2174/0929867327666200721160313openalex-extracted
Relationship between Gut Microbiota, Gut Hyperpermeability and Obesity
inferredcites →https://doi.org/10.2174/1573399813666170519103230openalex-extracted
Alternative Therapies for Diabetes: A Comparison of Western and Traditional Chinese Medicine (TCM) Approaches
inferredcites →https://doi.org/10.2337/db06-1491openalex-extracted
Metabolic Endotoxemia Initiates Obesity and Insulin Resistance
inferredcites →https://doi.org/10.2337/dc21-2358openalex-extracted
Gut Microbiome Composition Is Predictive of Incident Type 2 Diabetes in a Population Cohort of 5,572 Finnish Adults
inferredcites →https://doi.org/10.3389/fimmu.2021.740565openalex-extracted
Astragaloside IV Alleviates the Experimental DSS-Induced Colitis by Remodeling Macrophage Polarization Through STAT Signaling
inferredcites →https://doi.org/10.3389/fmicb.2018.02380openalex-extracted
Huang-Lian-Jie-Du-Decoction Ameliorates Hyperglycemia and Insulin Resistant in Association With Gut Microbiota Modulation
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A review of the botany, phytochemistry, traditional uses, pharmacology, toxicology, and quality control of the Astragalus memeranaceus
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Gut Microbiota and Intestinal Trans-Epithelial Permeability
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The Firmicutes/Bacteroidetes Ratio: A Relevant Marker of Gut Dysbiosis in Obese Patients?
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