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Lc-Ms/Ms Analyzing Praziquantel and 4-Hydroxypraziquantel Enantiomers in Black Goat Plasma and Mechanism of Stereoselective Pharmacokinetics

https://doi.org/10.2139/ssrn.4797526
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In vitro and in vivo human metabolism and pharmacokinetics of S‐ and R‐praziquantel
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Clinically relevant enantiomer specific R‐ and S‐praziquantel pharmacokinetic drug‐drug interactions with efavirenz and ritonavir
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The effect of ketoconazole on praziquantel pharmacokinetics and the role of CYP3A4 in the formation of X-OH-praziquantel and not 4-OH-praziquantel
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High-performance liquid chromatographic determination of the stereoselective biotransformation of the chiral drug praziquantel
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Praziquantel analogs with activity against juvenile Schistosoma mansoni
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Development of chiral praziquantel analogues as potential drug candidates with activity to juvenile Schistosoma japonicum
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Comparative efficacy and bioavailability of different praziquantel brands
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Testing of water samples for environmental DNA as a surveillance tool to assess the risk of schistosome infection in a locality
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Enantioselective analysis of praziquantel and trans-4-hydroxypraziquantel in human plasma by chiral LC–MS/MS: Application to pharmacokinetics
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A quantification method for determination of racemate praziquantel and R-enantiomer in rat plasma for comparison of their pharmacokinetics
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Simultaneous determination of albendazole metabolites, praziquantel and its metabolite in plasma by high-performance liquid chromatography–electrospray mass spectrometry
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Development and validation of an enantioselective LC–MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in human plasma, blood and dried blood spots
inferredcites →https://doi.org/10.1016/j.jpha.2015.12.004openalex-extracted
Significance and challenges of stereoselectivity assessing methods in drug metabolism
inferredcites →https://doi.org/10.1016/j.molbiopara.2014.06.002openalex-extracted
Schistosomiasis control: praziquantel forever?
inferredcites →https://doi.org/10.1016/j.talanta.2017.05.026openalex-extracted
Chromatographic separation of racemic praziquantel and its residual determination in perch by LC-MS/MS
inferredcites →https://doi.org/10.1016/s0168-8510(98)00002-5openalex-extracted
Dilemmas in drug development for tropical diseases
inferredcites →https://doi.org/10.1016/s1473-3099(15)00066-3openalex-extracted
Spatial distribution of schistosomiasis and treatment needs in sub-Saharan Africa: a systematic review and geostatistical analysis
inferredcites →https://doi.org/10.1021/acs.jafc.8b04728openalex-extracted
Selective Depletion of Chiral 4-Hydroxypraziquantel Metabolites in Three Types of Aquaculture Fish by LC-MS/MS
inferredcites →https://doi.org/10.1038/aps.2013.78openalex-extracted
Stereoselective binding of chiral drugs to plasma proteins
inferredcites →https://doi.org/10.1038/s41598-021-97409-xopenalex-extracted
Optimal single sampling time-point for monitoring of praziquantel exposure in children
inferredcites →https://doi.org/10.1080/19440049.2022.2032380openalex-extracted
Simultaneous determination of praziquantel and its main metabolites in the tissues of black goats and their residue depletion
inferredcites →https://doi.org/10.1093/infdis/jiy029openalex-extracted
Rodents as Natural Hosts of Zoonotic Schistosoma Species and Hybrids: An Epidemiological and Evolutionary Perspective From West Africa
inferredcites →https://doi.org/10.1111/j.1365-2125.2010.03874.xopenalex-extracted
Albendazole‐praziquantel interaction in healthy volunteers: kinetic disposition, metabolism and enantioselectivity
inferredcites →https://doi.org/10.1111/j.1365-2710.2007.00862.xopenalex-extracted
Pharmacokinetic interaction between ketoconazole and praziquantel in healthy volunteers
inferredcites →https://doi.org/10.1111/jvp.12769openalex-extracted
Investigation of pharmacokinetic interaction between ivermectin and praziquantel after oral administration in healthy dogs
inferredcites →https://doi.org/10.1128/aac.02253-17openalex-extracted
Pharmacokinetics of Praziquantel in Schistosoma mansoni- and Schistosoma haematobium-Infected School- and Preschool-Aged Children
inferredcites →https://doi.org/10.1128/mbio.00227-16openalex-extracted
Population Pharmacokinetics and Pharmacodynamics of Praziquantel in Ugandan Children with Intestinal Schistosomiasis: Higher Dosages Are Required for Maximal Efficacy
inferredcites →https://doi.org/10.1177/1098612x17734065openalex-extracted
Pharmacokinetics of praziquantel and pyrantel pamoate combination following oral administration in cats
inferredcites →https://doi.org/10.1186/s12917-015-0400-2openalex-extracted
Comparison of praziquantel pharmacokinetics and tissue distribution in fresh and brackish water cultured grass carp (ctenopharyngodon idellus) after oral administration of single bolus
inferredcites →https://doi.org/10.1186/s12917-020-02667-yopenalex-extracted
Prevalence and distribution of livestock schistosomiasis and fascioliasis in Côte d’Ivoire: results from a cross-sectional survey
inferredcites →https://doi.org/10.1186/s13071-020-04420-8openalex-extracted
Evaluation of a real-time PCR assay for diagnosis of schistosomiasis japonica in the domestic goat
inferredcites →https://doi.org/10.1186/s40249-017-0357-4openalex-extracted
Slow-release praziquantel for dogs: presentation of a new formulation for echinococcosis control
inferredcites →https://doi.org/10.1371/journal.pntd.0002110openalex-extracted
Introgressive Hybridization of Schistosoma haematobium Group Species in Senegal: Species Barrier Break Down between Ruminant and Human Schistosomes
inferredcites →https://doi.org/10.1371/journal.pntd.0003861openalex-extracted
Differences in the Faecal Microbiome in Schistosoma haematobium Infected Children vs. Uninfected Children
inferredcites →https://doi.org/10.1371/journal.pntd.0004700openalex-extracted
Pharmacokinetic Study of Praziquantel Enantiomers and Its Main Metabolite R-trans-4-OH-PZQ in Plasma, Blood and Dried Blood Spots in Opisthorchis viverrini-Infected Patients
inferredcites →https://doi.org/10.1371/journal.pntd.0008649openalex-extracted
Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models
inferredcites →https://doi.org/10.2133/dmpk.dmpk-10-rg-041openalex-extracted
Metabolite Profiling of Praziquantel and its Analogs During the Analysis of in vitro Metabolic Stability Using Information-Dependent Acquisition on a Hybrid Triple Quadrupole Linear Ion Trap Mass Spectrometer
inferredcites →https://doi.org/10.2471/blt.14.143065openalex-extracted
Water buffalo as sentinel animals for schistosomiasis surveillance
inferredcites →https://doi.org/10.3354/dao02979openalex-extracted
Pharmacokinetics and residue depletion of praziquantel in rice field eels Monopterus albus
inferredcites →https://doi.org/10.3389/fgene.2014.00230openalex-extracted
Schistosomes and snails: a molecular encounter
inferredcites →https://doi.org/10.3390/molecules26113113openalex-extracted
Enantioselectivity in Drug Pharmacokinetics and Toxicity: Pharmacological Relevance and Analytical Methods
inferredcites →https://doi.org/10.3390/ph14050400openalex-extracted
Effect of Dihydroartemisinin-Piperaquine on the Pharmacokinetics of Praziquantel for Treatment of Schistosoma mansoni Infection
inferredcites →https://doi.org/10.3390/tropicalmed3020068openalex-extracted
Schistosome Vaccines for Domestic Animals
inferredcites →https://doi.org/10.3947/ic.2018.50.1.1openalex-extracted
Albendazole and Praziquantel: Review and Safety Monitoring in Korea
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