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Therapeutic Potential of Cynaroside as a Novel Granzyme B Inhibitor in Inflammatory Skin Conditions

https://doi.org/10.2139/ssrn.4898640
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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jcb.23121openalex-snapshot
Protective effects of cynaroside against H2O2-induced apoptosis in H9c2 cardiomyoblasts
inferredcites →https://doi.org/10.1002/jcc.21334openalex-snapshot
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
inferredcites →https://doi.org/10.1002/jcp.30609openalex-snapshot
MAP kinase/ERK kinase 1 (MEK1) phosphorylates regulator of calcineurin 1 (RCAN1) to regulate neuronal differentiation
inferredcites →https://doi.org/10.1006/meth.2001.1262openalex-snapshot
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
inferredcites →https://doi.org/10.1016/j.ejmech.2020.112754openalex-snapshot
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors
inferredcites →https://doi.org/10.1016/j.ejphar.2021.174522openalex-snapshot
Protective effect of cynaroside on sepsis-induced multiple organ injury through Nrf2/HO-1-dependent macrophage polarization
inferredcites →https://doi.org/10.1016/j.jdermsci.2016.09.009openalex-snapshot
Relationships among plasma granzyme B level, pruritus and dermatitis in patients with atopic dermatitis
inferredcites →https://doi.org/10.1016/j.jid.2020.05.095openalex-snapshot
Granzyme B Contributes to Barrier Dysfunction in Oxazolone-Induced Skin Inflammation through E-Cadherin and FLG Cleavage
inferredcites →https://doi.org/10.1016/j.jid.2020.07.011openalex-snapshot
Granzyme B Inhibition by Tofacitinib Blocks the Pathology Induced by CD8 T Cells in Cutaneous Leishmaniasis
inferredcites →https://doi.org/10.1016/j.matbio.2017.12.005openalex-snapshot
Granzyme B in skin inflammation and disease
inferredcites →https://doi.org/10.1016/j.molmed.2012.09.009openalex-snapshot
Granzyme B in injury, inflammation, and repair
inferredcites →https://doi.org/10.1016/s0014-5793(04)00187-5openalex-snapshot
Killing of target cells by redirected granzyme B in the absence of perforin
inferredcites →https://doi.org/10.1021/ci300604zopenalex-snapshot
Lessons Learned in Empirical Scoring with smina from the CSAR 2011 Benchmarking Exercise
inferredcites →https://doi.org/10.1021/ct700200bopenalex-snapshot
P-LINCS: A Parallel Linear Constraint Solver for Molecular Simulation
inferredcites →https://doi.org/10.1038/377446a0openalex-snapshot
Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B
inferredcites →https://doi.org/10.1038/cdd.2009.169openalex-snapshot
Control of granzymes by serpins
inferredcites →https://doi.org/10.1038/nri1083openalex-snapshot
The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal
inferredcites →https://doi.org/10.1038/s12276-018-0095-0openalex-snapshot
Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing
inferredcites →https://doi.org/10.1038/sj.bjc.6601051openalex-snapshot
Expression of endogenous granzyme B in a subset of human primary breast carcinomas
inferredcites →https://doi.org/10.1038/sj.cdd.4402183openalex-snapshot
Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin
inferredcites →https://doi.org/10.1074/jbc.m111.232165openalex-snapshot
The Regulator of Calcineurin 1 (RCAN1/DSCR1) Activates the cAMP Response Element-binding Protein (CREB) Pathway
inferredcites →https://doi.org/10.1074/jbc.m512694200openalex-snapshot
Human Keratinocytes Acquire Cellular Cytotoxicity under UV-B Irradiation
inferredcites →https://doi.org/10.1093/molehr/7.12.1133openalex-snapshot
Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction
inferredcites →https://doi.org/10.1111/acel.12298openalex-snapshot
Granzyme B mediates both direct and indirect cleavage of extracellular matrix in skin after chronic low‐dose ultraviolet light irradiation
inferredcites →https://doi.org/10.1146/annurev.immunol.20.100201.131730openalex-snapshot
Lymphocyte-Mediated Cytotoxicity
inferredcites →https://doi.org/10.1182/blood-2002-02-0638openalex-snapshot
Subtractive hybridization reveals the expression of immunoglobulinlike transcript 7, Eph-B1, granzyme B, and 3 novel transcripts in human plasmacytoid dendritic cells
inferredcites →https://doi.org/10.3390/molecules29071508openalex-snapshot
Cynaroside Induces G1 Cell Cycle Arrest by Downregulating Cell Division Cycle 25A in Colorectal Cancer
inferredcites →https://doi.org/10.4049/jimmunol.129.4.1612openalex-snapshot
Fibronectin fragment(s) are chemotactic for human peripheral blood monocytes.
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