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Effects of Crispr/ Cas9-Mediated Igfbp3 Gene Knockout on Proliferation and Apoptosis of Antler Stem Cells

https://doi.org/10.2139/ssrn.5139360
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Outgoing claims: the papers this work cites, builds on, or argues with.

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TGF‐β‐induced IGFBP‐3 is a key paracrine factor from activated pericytes that promotes colorectal cancer cell migration and invasion
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Deer antler regeneration: A stem cell‐based epimorphic process
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Gene expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation
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Deer antler – A novel model for studying organ regeneration in mammals
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Individual Cells Can Resolve Variations in Stimulus Intensity along the IGF-PI3K-AKT Signaling Axis
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The First High-Quality Reference Genome of Sika Deer Provides Insights into High-Tannin Adaptation
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IGF binding proteins in cancer: mechanistic and clinical insights
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Clinical use of lentiviral vectors
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Deer antler stem cells are a novel type of cells that sustain full regeneration of a mammalian organ—deer antler
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Runx1 promotes angiogenesis by downregulation of insulin-like growth factor-binding protein-3
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Biological significance of a family of regularly spaced repeats in the genomes of Archaea, Bacteria and mitochondria
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Insulin-like Growth Factor-binding Protein-3 Plays an Important Role in Regulating Pharyngeal Skeleton and Inner Ear Formation and Differentiation
inferredcites →https://doi.org/10.1080/15384101.2016.1274471openalex-snapshot
IGF1 regulates RUNX1 expression via IRS1/2: Implications for antler chondrocyte differentiation
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Chordin Like-1 Regulates Osteoblast and Adipocyte Differentiation Through Stabilizing Insulin-Like Growth Factor Binding Protein 3
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Large-scale Clinical-grade Retroviral Vector Production in a Fixed-Bed Bioreactor
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Mitogen signaling strength and duration can control cell cycle decisions
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Temporal integration of mitogen history in mother cells controls proliferation of daughter cells
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A population of stem cells with strong regenerative potential discovered in deer antlers
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Stem cells drive antler regeneration
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Transcriptomic analysis of different tissue layers in antler growth Center in Sika Deer (Cervus nippon)
inferredcites →https://doi.org/10.1186/s12943-022-01518-8openalex-snapshot
Current applications and future perspective of CRISPR/Cas9 gene editing in cancer
inferredcites →https://doi.org/10.1186/s41065-020-00137-xopenalex-snapshot
Development of novel EST microsatellite markers for genetic diversity analysis and correlation analysis of velvet antler growth characteristics in Sika deer
inferredcites →https://doi.org/10.1530/jme-17-0311openalex-snapshot
40 YEARS OF IGF1: IGF1 receptor signaling pathways
inferredcites →https://doi.org/10.2147/cmar.s234291openalex-snapshot
IGFBP-3 Is the Key Target of Sanguinarine in Promoting Apoptosis in Hepatocellular Carcinoma
inferredcites →https://doi.org/10.3389/fvets.2021.630686openalex-snapshot
Effects of Arginine Supplementation on Serum Metabolites and the Rumen Bacterial Community of Sika Deer (Cervus nippon)
inferredcites →https://doi.org/10.3390/cells10123327openalex-snapshot
Regulation of Cell Cycle Progression by Growth Factor-Induced Cell Signaling
inferredcites →https://doi.org/10.3892/ijmm.2016.2820openalex-snapshot
Bone marrow-derived mesenchymal stem cells modified with IGFBP-3 inhibit the proliferation of pulmonary artery smooth muscle cells
inferredcites →https://doi.org/10.5713/ab.23.0421openalex-snapshot
The spatio-temporal expression analysis of parathyroid hormone like hormone gene provides a new insight for bone growth of the antler tip tissue in sika deer
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