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Antigenic Seniority and Convergent Haemagglutinin Evolution Shaped the Immune Landscape Preceding Influenza B/Yamagata’s Extinction

https://doi.org/10.2139/ssrn.6794361
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/viro.2002.1719openalex-snapshot
Reappearance and Global Spread of Variants of Influenza B/Victoria/2/87 Lineage Viruses in the 2000–2001 and 2001–2002 Seasons
inferredcites →https://doi.org/10.1016/j.cell.2021.01.037openalex-snapshot
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity
inferredcites →https://doi.org/10.1016/j.jviromet.2026.115406openalex-snapshot
Development of an ELISA-based pulldown approach for functional analysis of antigen-specific antibodies
inferredcites →https://doi.org/10.1016/j.vaccine.2008.07.064openalex-snapshot
Animal influenza epidemiology
inferredcites →https://doi.org/10.1016/j.virol.2013.07.035openalex-snapshot
Structural basis for the divergent evolution of influenza B virus hemagglutinin
inferredcites →https://doi.org/10.1016/j.virusres.2022.198926openalex-snapshot
Molecular characterization and evolution dynamics of influenza B viruses circulating in Germany from season 1996/1997 to 2019/2020
inferredcites →https://doi.org/10.1016/s0006-3495(02)75302-2openalex-snapshot
Differences in Electrostatic Properties at Antibody–Antigen Binding Sites: Implications for Specificity and Cross-Reactivity
inferredcites →https://doi.org/10.1016/s2666-5247(24)00066-1openalex-snapshot
Probable extinction of influenza B/Yamagata and its public health implications: a systematic literature review and assessment of global surveillance databases
inferredcites →https://doi.org/10.1038/s41467-018-06228-8openalex-snapshot
A naturally protective epitope of limited variability as an influenza vaccine target
inferredcites →https://doi.org/10.1038/s41467-018-08165-yopenalex-snapshot
Cross-lineage protection by human antibodies binding the influenza B hemagglutinin
inferredcites →https://doi.org/10.1038/s41467-025-65396-6openalex-snapshot
Unraveling the mechanism behind the probable extinction of the B/Yamagata lineage of influenza B viruses
inferredcites →https://doi.org/10.1038/s41598-023-43003-2openalex-snapshot
A computationally optimized broadly reactive hemagglutinin vaccine elicits neutralizing antibodies against influenza B viruses from both lineages
inferredcites →https://doi.org/10.1038/srep32973openalex-snapshot
Sterilizing immunity to influenza virus infection requires local antigen-specific T cell response in the lungs
inferredcites →https://doi.org/10.1073/pnas.2211616119openalex-snapshot
Substitutions near the HA receptor binding site explain the origin and major antigenic change of the B/Victoria and B/Yamagata lineages
inferredcites →https://doi.org/10.1073/pnas.2301549120openalex-snapshot
Structural evolution of an immune evasion determinant shapes pathogen host tropism
inferredcites →https://doi.org/10.1080/14760584.2024.2343689openalex-snapshot
Anti-neuraminidase immunity in the combat against influenza
inferredcites →https://doi.org/10.1080/14760584.2025.2515597openalex-snapshot
Maintaining the value of influenza vaccination – the shift from quadrivalent to trivalent vaccines: an expert review
inferredcites →https://doi.org/10.1111/irv.12319openalex-snapshot
Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study
inferredcites →https://doi.org/10.1111/irv.13359openalex-snapshot
Prevalence of Influenza B/Yamagata Viruses From Season 2012/2013 to 2021/2022 in Italy as an Indication of a Potential Lineage Extinction
inferredcites →https://doi.org/10.1111/irv.70188openalex-snapshot
Immunity to Influenza B/Yamagata‐Lineage Viruses Has Not Waned Since the Disappearance of This Virus Lineage
inferredcites →https://doi.org/10.1126/sciadv.adu3344openalex-snapshot
Neuraminidase-specific antibodies drive differential cross-protection between contemporary FLUBV lineages
inferredcites →https://doi.org/10.1126/science.adq3003openalex-snapshot
COVID-19 pandemic interventions reshaped the global dispersal of seasonal influenza viruses
inferredcites →https://doi.org/10.1371/journal.pone.0038929openalex-snapshot
Cross-Lineage Influenza B and Heterologous Influenza A Antibody Responses in Vaccinated Mice: Immunologic Interactions and B/Yamagata Dominance
inferredcites →https://doi.org/10.1371/journal.pone.0222381openalex-snapshot
The epidemiological signature of influenza B virus and its B/Victoria and B/Yamagata lineages in the 21st century
inferredcites →https://doi.org/10.1371/journal.ppat.1006749openalex-snapshot
Genome-wide evolutionary dynamics of influenza B viruses on a global scale
inferredcites →https://doi.org/10.2807/1560-7917.es.2022.27.39.2200753openalex-snapshot
Has influenza B/Yamagata become extinct and what implications might this have for quadrivalent influenza vaccines?
inferredcites →https://doi.org/10.3390/ijms26157476openalex-snapshot
The Persistence of Cross-Reactive Immunity to Influenza B/Yamagata Neuraminidase Despite the Disappearance of the Lineage: Structural and Serological Evidence
inferredcites →https://doi.org/10.3390/v14081745openalex-snapshot
Extinction of the Influenza B Yamagata Line during the COVID Pandemic—Implications for Vaccine Composition
inferredcites →https://doi.org/10.3390/v15102032openalex-snapshot
Existing Evidence for Influenza B Virus Adaptations to Drive Replication in Humans as the Primary Host
inferredcites →https://doi.org/10.3390/vaccines10040606openalex-snapshot
Effect of COVID-19 Pandemic on Influenza Vaccination Intention: A Meta-Analysis and Systematic Review
inferredcites →https://doi.org/10.3390/vaccines8010125openalex-snapshot
Immune Pressure on Polymorphous Influenza B Populations Results in Diverse Hemagglutinin Escape Mutants and Lineage Switching
inferredcites →https://doi.org/10.7554/elife.01914openalex-snapshot
Integrating influenza antigenic dynamics with molecular evolution
inferredcites →https://doi.org/10.7554/elife.05055openalex-snapshot
The contrasting phylodynamics of human influenza B viruses

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inferred← citeshttps://doi.org/10.3390/antib15040075openalex-snapshot
Advances in the Development of a Universal Influenza Vaccine
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