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Progress Towards the Discovery of Xanthine Oxidase Inhibitors
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inferred← citeshttps://doi.org/10.3897/pharmacia.71.e127845zenodo-depositor-declared
Prediction of ADMET, molecular docking, DFT, and QSPR of potential phytoconstituents from Ambrosia maritima L. targeting xanthine oxidase
inferred← citeshttps://doi.org/10.1002/9780470048672.wecb721openalex-snapshot
Microbial Natural Products: Chemical Diversity
inferred← citeshttps://doi.org/10.1002/9781118819951.ch17openalex-snapshot
Febuxostat (Uloric): A Xanthine Oxidase Inhibitor for the Treatment of Gout
inferred← citeshttps://doi.org/10.1002/9781119436713.ch5openalex-snapshot
Nutraceuticals and Natural Product Derivatives in the Premises of Disease Prevention
inferred← citeshttps://doi.org/10.1002/9781119650034.ch11openalex-snapshot
Secondary Metabolites and Toxins of Microbial Origin for the Treatment of Diseases
inferred← citeshttps://doi.org/10.1002/9783527651085.ch15openalex-snapshot
A New‐Generation Uric Acid Production Inhibitor: Febuxostat
inferred← citeshttps://doi.org/10.1002/adhm.201200423openalex-snapshot
Current Progress in Reactive Oxygen Species (ROS)‐Responsive Materials for Biomedical Applications
inferred← citeshttps://doi.org/10.1002/ardp.201200296openalex-snapshot
Design and Synthesis of Aza‐Flavones as a New Class of Xanthine Oxidase Inhibitors
inferred← citeshttps://doi.org/10.1002/ardp.201400031openalex-snapshot
4,6‐Diaryl/heteroarylpyrimidin‐2(1H)‐ones as a New Class of Xanthine Oxidase Inhibitors
inferred← citeshttps://doi.org/10.1002/ardp.201800165openalex-snapshot
Xanthine oxidase inhibitory activity of new pyrrole carboxamide derivatives: In vitro and in silico studies
inferred← citeshttps://doi.org/10.1002/ardp.202300296openalex-snapshot
Triazole derivatives as potential xanthine oxidase inhibitors: Design, enzyme inhibition potential, and docking studies
inferred← citeshttps://doi.org/10.1002/bmc.4852openalex-snapshot
Rapid screening and evaluation of XOD inhibitors and O2•− scavenger from total flavonoids of Ginkgo biloba leaves by LC–MS and multimode microplate reader
inferred← citeshttps://doi.org/10.1002/cmdc.201100054openalex-snapshot
Inhibition of Xanthine Oxidase by Thiosemicarbazones, Hydrazones and Dithiocarbazates Derived from Hydroxy‐Substituted Benzaldehydes
inferred← citeshttps://doi.org/10.1002/elps.202000083openalex-snapshot
Evaluation of xanthine oxidase inhibitory activity of flavonoids by an online capillary electrophoresis‐based immobilized enzyme microreactor
inferred← citeshttps://doi.org/10.1002/em.20146openalex-snapshot
Involvement of oxygen free radicals in the serum‐mediated increase of benzoquinone genotoxicity
inferred← citeshttps://doi.org/10.1002/ffj.70044openalex-snapshot
Effect of Harvesting at Different Times on Antioxidant Potential and Phytochemical Contents of Kickxia lanigera and Kickxia spuria subsp. integrifolia : In Vitro and In Silico Studies
inferred← citeshttps://doi.org/10.1002/jbt.22005openalex-snapshot
Potential cow milk xanthine oxidase inhibitory and antioxidant activity of selected phenolic acid derivatives
inferred← citeshttps://doi.org/10.1002/jcp.21463openalex-snapshot
Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells
inferred← citeshttps://doi.org/10.1002/jcp.22989openalex-snapshot
Effects of moderate electrical stimulation on reactive species production by primary rat skeletal muscle cells: Cross talk between superoxide and nitric oxide production
inferred← citeshttps://doi.org/10.1002/jhet.4796openalex-snapshot
Recent developments in synthetic strategies and pharmacological outcomes of synthetic xanthine oxidase inhibitors: A comprehensive review
inferred← citeshttps://doi.org/10.1002/jssc.201301207openalex-snapshot
Screening of xanthine oxidase inhibitors in complex mixtures using online HPLC coupled with postcolumn fluorescence‐based biochemical detection
inferred← citeshttps://doi.org/10.1002/med.21457openalex-snapshot
Toward an Understanding of Structural Insights of Xanthine and Aldehyde Oxidases: An Overview of their Inhibitors and Role in Various Diseases
inferred← citeshttps://doi.org/10.1002/mus.20743openalex-snapshot
Oxidative stress, chronic disease, and muscle wasting
inferred← citeshttps://doi.org/10.1002/pca.874openalex-snapshot
A rapid TLC autographic method for the detection of xanthine oxidase inhibitors and superoxide scavengers
inferred← citeshttps://doi.org/10.1002/poc.923openalex-snapshot
Theoretical estimation of the annular tautomerism of indazoles
inferred← citeshttps://doi.org/10.1002/slct.202103581openalex-snapshot
Potential Anti‐hyperuricemic Agents from Proanthocyanidins, Procyanidins, and Benzophenone Glucosides via In Silico Docking Analysis Verified with In Vitro Bioassay
inferred← citeshttps://doi.org/10.1007/978-3-540-36841-0_53openalex-snapshot
Natural Flavonoids for the treatment of Hyperuricemia, Molecular Docking studies
inferred← citeshttps://doi.org/10.1007/978-3-642-30018-9_42openalex-snapshot
Overview of Oxidative Stress and Cardiovascular Disease
inferred← citeshttps://doi.org/10.1007/978-981-16-7055-8_18openalex-snapshot
Cardiovascular Protection Effect
inferred← citeshttps://doi.org/10.1007/978-981-96-9670-3_11openalex-snapshot
Elucidating the Impact of Reactive Molecules on Cell Signaling Networks to Illuminate Their Contribution to the Etiology and Progression of Human Diseases
inferred← citeshttps://doi.org/10.1007/bf03345734openalex-snapshot
The role of allopurinol on oxidative stress in experimental hyperthyroidism
inferred← citeshttps://doi.org/10.1007/s00011-003-1184-6openalex-snapshot
Allopurinol inhibits CXC chemokine expression and leukocyte adhesion in endotoxemic liver injury
inferred← citeshttps://doi.org/10.1007/s00044-014-1295-3openalex-snapshot
A comprehensive review on bioactive fused heterocycles as purine-utilizing enzymes inhibitors
inferred← citeshttps://doi.org/10.1007/s00044-015-1382-0openalex-snapshot
Screening of a library of 4-aryl/heteroaryl-4H-fused pyrans for xanthine oxidase inhibition: synthesis, biological evaluation and docking studies
inferred← citeshttps://doi.org/10.1007/s00044-019-02461-yopenalex-snapshot
Thiazole-5-carboxylic acid derivatives as potent xanthine oxidase inhibitors: design, synthesis, in vitro evaluation, and molecular modeling studies
inferred← citeshttps://doi.org/10.1007/s00044-020-02589-2openalex-snapshot
Design, synthesis and biological evaluation of novel indolinedione–coumarin hybrids as xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1007/s00044-022-02902-1openalex-snapshot
Platanic acid derived amides are more cytotoxic than their corresponding oximes
inferred← citeshttps://doi.org/10.1007/s00044-025-03395-4openalex-snapshot
Naphthoquinones and tricyclic derivatives: in vitro evaluation as xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1007/s00204-013-1034-4openalex-snapshot
Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis
inferred← citeshttps://doi.org/10.1007/s00216-013-7612-8openalex-snapshot
Discovery of xanthine oxidase inhibitors from a complex mixture using an online, restricted-access material coupled with column-switching liquid chromatography with a diode-array detection system
inferred← citeshttps://doi.org/10.1007/s00216-014-7902-9openalex-snapshot
Affinity selection-based two-dimensional chromatography coupled with high-performance liquid chromatography-mass spectrometry for discovering xanthine oxidase inhibitors from Radix Salviae Miltiorrhizae
inferred← citeshttps://doi.org/10.1007/s00216-014-8132-xopenalex-snapshot
Rapid screening and detection of XOD inhibitors from S. tamariscina by ultrafiltration LC-PDA–ESI-MS combined with HPCCC
inferred← citeshttps://doi.org/10.1007/s00268-007-9336-4openalex-snapshot
The Potential Role for Xanthine Oxidase Inhibition in Major Intra‐abdominal Surgery
inferred← citeshttps://doi.org/10.1007/s00383-007-2009-4openalex-snapshot
Role of allopurinol on oxidative stress in caustic burn: cure for stricture?
inferred← citeshttps://doi.org/10.1007/s00540-021-02983-zopenalex-snapshot
Allopurinol attenuates postoperative pain and modulates the purinergic system in patients undergoing abdominal hysterectomy: a randomized controlled trial
inferred← citeshttps://doi.org/10.1007/s00604-025-07167-0openalex-snapshot
Preparation of immobilized xanthine oxidase with magnetic metal–organic framework and its application in screening of active ingredients in traditional Chinese medicine
inferred← citeshttps://doi.org/10.1007/s00706-020-02687-2openalex-snapshot
The (NHC)PdBr2(2-aminopyridine) complexes: synthesis, characterization, molecular docking study, and inhibitor effects on the human serum carbonic anhydrase and serum bovine xanthine oxidase
inferred← citeshttps://doi.org/10.1007/s00706-021-02831-6openalex-snapshot
A study about excellent xanthine oxidase inhibitory effects of new pyridine salts
inferred← citeshttps://doi.org/10.1007/s10126-003-0027-3openalex-snapshot
Enzyme Inhibitors of Marine Microbial Origin with Pharmaceutical Importance
inferred← citeshttps://doi.org/10.1007/s11030-024-10962-1openalex-snapshot
A comprehensive review of synthetic and semisynthetic xanthine oxidase inhibitors: identification of potential leads based on in-silico computed ADME characteristics
inferred← citeshttps://doi.org/10.1007/s11094-025-03320-4openalex-snapshot
Density Functional Theory, Molecular-Docking Studies and Inhibition Effects of Pharmaceutical Active Ingredients on Xanthine Oxidase
inferred← citeshttps://doi.org/10.1007/s11101-012-9265-1openalex-snapshot
Role of ROS and COX-2/iNOS inhibition in cancer chemoprevention: a review
inferred← citeshttps://doi.org/10.1007/s11926-004-0075-3openalex-snapshot
Serum uric acid-lowering therapies: Where are we heading in management of hyperuricemia and the potential role of uricase
inferred← citeshttps://doi.org/10.1007/s11926-013-0396-1openalex-snapshot
Uric Acid and Xanthine Oxidoreductase in Wound Healing
inferred← citeshttps://doi.org/10.1007/s12088-025-01534-4openalex-snapshot
Inhibition of Xanthine Oxidase by 1-O-Methyl Chrysophanol, A Hydroxyanthraquinone Isolated from Amycolatopsis Thermoflava ICTA 103
inferred← citeshttps://doi.org/10.1007/s12649-024-02443-1openalex-snapshot
Bioactive Potential of Baby Corn Silk: In-Vitro Evaluation of Antioxidant, Antimicrobial, Anti-diabetic, and Anti-gout Activities
inferred← citeshttps://doi.org/10.1007/s13105-011-0117-zopenalex-snapshot
Effects of Greek legume plant extracts on xanthine oxidase, catalase and superoxide dismutase activities
inferred← citeshttps://doi.org/10.1007/s13596-012-0100-4openalex-snapshot
In vitro xanthine oxidase inhibitory and antioxidant activities of aerial parts of Flacourtia sepiaria Roxb
inferred← citeshttps://doi.org/10.1007/s42250-025-01507-6openalex-snapshot
Antioxidant Activity of Hydroxyquinolone Derivatives: Experimental, Computational, Hirshfeld Surface, and ADMET Analyses
inferred← citeshttps://doi.org/10.1007/s43450-025-00681-5openalex-snapshot
Artemisia vulgaris Extract: A Multi-approach Study on Its Anti-gout Potential Through Xanthine Oxidase Inhibition, Antioxidant Activity, and Pharmacokinetics
inferred← citeshttps://doi.org/10.1016/b978-0-12-813855-7.00003-9openalex-snapshot
Carbon Electrodes in Electrochemical Analysis of Biomolecules and Bioactive Substances
inferred← citeshttps://doi.org/10.1016/b978-0-12-817903-1.00013-9openalex-snapshot
Bioactive natural products as potent inhibitors of xanthine oxidase
inferred← citeshttps://doi.org/10.1016/b978-008055232-3.60496-9openalex-snapshot
Xanthine Oxidoreductase
inferred← citeshttps://doi.org/10.1016/j.abb.2026.110948openalex-snapshot
Inhibition of xanthine oxidase by orientin, a C-glycosylated flavonoid: Kinetic characterization and molecular simulation
inferred← citeshttps://doi.org/10.1016/j.aca.2009.01.037openalex-snapshot
Measurement of xanthine oxidase inhibition activity of phenolics and flavonoids with a modified cupric reducing antioxidant capacity (CUPRAC) method
inferred← citeshttps://doi.org/10.1016/j.aca.2020.10.010openalex-snapshot
Flexible enzyme cascade sensing platform based on a G-quadruplex nanofiber biohydrogel for target colorimetric sensing
inferred← citeshttps://doi.org/10.1016/j.addr.2015.05.005openalex-snapshot
Enzyme therapeutics for systemic detoxification
inferred← citeshttps://doi.org/10.1016/j.biocel.2006.07.001openalex-snapshot
Free radicals and antioxidants in normal physiological functions and human disease
inferred← citeshttps://doi.org/10.1016/j.bionut.2014.07.005openalex-snapshot
Isolation of a bioactive flavonoid from Spilanthes calva D.C. in vitro xanthine oxidase assay and in silico study
inferred← citeshttps://doi.org/10.1016/j.bioorg.2014.08.007openalex-snapshot
Synthesis and xanthine oxidase inhibitory activity of 5,6-dihydropyrazolo/pyrazolo[1,5-c]quinazoline derivatives
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.02.049openalex-snapshot
Synthesis and characterization of CAPE derivatives as xanthine oxidase inhibitors with radical scavenging properties
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.104948openalex-snapshot
Febuxostat-based amides and some derived heterocycles targeting xanthine oxidase and COX inhibition. Synthesis, in vitro and in vivo biological evaluation, molecular modeling and in silico ADMET studies
inferred← citeshttps://doi.org/10.1016/j.bioorg.2022.106064openalex-snapshot
A possible covalent xanthine oxidase inhibitor TS10: Inhibition mechanism, metabolites identification and PDPK assessment
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.04.031openalex-snapshot
Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats
inferred← citeshttps://doi.org/10.1016/j.bmc.2011.01.058openalex-snapshot
A rational approach for the design and synthesis of 1-acetyl-3,5-diaryl-4,5-dihydro(1H)pyrazoles as a new class of potential non-purine xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmc.2011.07.039openalex-snapshot
N-(1,3-Diaryl-3-oxopropyl)amides as a new template for xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmc.2015.12.024openalex-snapshot
Hydroxylated chalcones with dual properties: Xanthine oxidase inhibitors and radical scavengers
inferred← citeshttps://doi.org/10.1016/j.bmc.2017.02.044openalex-snapshot
Xanthine oxidase inhibitory activity of nicotino/isonicotinohydrazides: A systematic approach from in vitro, in silico to in vivo studies
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.10.029openalex-snapshot
Isocytosine-based inhibitors of xanthine oxidase: Design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia
inferred← citeshttps://doi.org/10.1016/j.bmcl.2013.12.031openalex-snapshot
Microwave assisted synthesis of naphthopyrans catalysed by silica supported fluoroboric acid as a new class of non purine xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2014.01.050openalex-snapshot
HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase
inferred← citeshttps://doi.org/10.1016/j.bmcl.2014.07.041openalex-snapshot
Synthesis and evaluation of naphthoflavones as a new class of non purine xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2019.01.005openalex-snapshot
Discovery of 2-phenylthiazole-4-carboxylic acid, a novel and potent scaffold as xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.canlet.2010.07.015openalex-snapshot
Targeting apoptosis pathways in cancer by Chinese medicine
inferred← citeshttps://doi.org/10.1016/j.cbi.2010.12.004openalex-snapshot
3,5,2′,4′-Tetrahydroxychalcone, a new non-purine xanthine oxidase inhibitor
inferred← citeshttps://doi.org/10.1016/j.cbi.2015.01.022openalex-snapshot
Xanthine oxidase inhibitory properties and anti-inflammatory activity of 2-amino-5-alkylidene-thiazol-4-ones
inferred← citeshttps://doi.org/10.1016/j.cbi.2023.110772openalex-snapshot
Chloro-substituted pyridine squaramates as new DNase I inhibitors: Synthesis, structural characterization, in vitro evaluation and molecular docking studies
inferred← citeshttps://doi.org/10.1016/j.ccr.2025.217377openalex-snapshot
Advances in nano‑molybdenum oxide: structural engineering progress in tumor theranostics
inferred← citeshttps://doi.org/10.1016/j.cgh.2006.11.020openalex-snapshot
Effect of Allopurinol on Clinical Outcomes in Inflammatory Bowel Disease Nonresponders to Azathioprine or 6-Mercaptopurine
inferred← citeshttps://doi.org/10.1016/j.ejmech.2014.01.058openalex-snapshot
Design, synthesis and molecular modeling of aloe-emodin derivatives as potent xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.ejmech.2014.08.014openalex-snapshot
Synthesis and bioevaluation of 2-phenyl-4-methyl-1,3-selenazole-5-carboxylic acids as potent xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.03.002openalex-snapshot
Synthesis, screening and docking of fused pyrano[3,2- d ]pyrimidine derivatives as xanthine oxidase inhibitor
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.04.031openalex-snapshot
Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.08.047openalex-snapshot
Synthesis and bioevaluation of 1-phenyl-pyrazole-4-carboxylic acid derivatives as potent xanthine oxidoreductase inhibitors
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.11.070openalex-snapshot
Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative agents
inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.01.096openalex-snapshot
Design, synthesis and biological evaluation of novel xanthine oxidase inhibitors bearing a 2-arylbenzo[b]furan scaffold
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116866openalex-snapshot
Rationally designed febuxostat-based hydroxamic acid and its pH-Responsive nanoformulation elicits anti-tumor activity
inferred← citeshttps://doi.org/10.1016/j.ejmech.2026.119214openalex-snapshot
Design, synthesis, and biological evaluation of benzoisonicotinamide derivatives as novel xanthine oxidase inhibitors guided by metabolic stability
inferred← citeshttps://doi.org/10.1016/j.ejphar.2021.174270openalex-snapshot
Xanthine oxidoreductase promotes the progression of colitis-associated colorectal cancer by causing DNA damage and mediating macrophage M1 polarization
inferred← citeshttps://doi.org/10.1016/j.ejphar.2021.174568openalex-snapshot
Gene-editing, immunological and iPSCs based therapeutics for muscular dystrophy
inferred← citeshttps://doi.org/10.1016/j.elecom.2005.08.009openalex-snapshot
Direct electrochemically driven catalysis of bovine milk xanthine oxidase
inferred← citeshttps://doi.org/10.1016/j.fbio.2023.103145openalex-snapshot
Identification of anti-hyperuricemic components from Cichorium intybus L. taproots
inferred← citeshttps://doi.org/10.1016/j.fct.2009.05.033openalex-snapshot
Boerhaavia diffusa: Metabolite profiling of a medicinal plant from Nyctaginaceae
inferred← citeshttps://doi.org/10.1016/j.fitote.2022.105388openalex-snapshot
Unusual N-pyridinium amino acid-type alkaloids from roots and rhizomes of Sophora tonkinensis Gagnep
inferred← citeshttps://doi.org/10.1016/j.foodchem.2009.12.002openalex-snapshot
Exploiting Catharanthus roseus roots: Source of antioxidants
inferred← citeshttps://doi.org/10.1016/j.foodchem.2012.05.015openalex-snapshot
Phytochemical investigations and biological potential screening with cellular and non-cellular models of globe amaranth (Gomphrena globosaL.) inflorescences
inferred← citeshttps://doi.org/10.1016/j.fshw.2015.11.001openalex-snapshot
Phenolics extract of Tetrapleura tetraptera fruit inhibits xanthine oxidase and Fe2+-induced lipid peroxidation in the kidney, liver, and lungs tissues of rats in vitro
inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e22483openalex-snapshot
A review of pomegranate supplementation: A promising remedial avenue for Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e29459openalex-snapshot
Phytochemical characterization and multifaceted bioactivity assessment of essential oil from Ptychotis verticillata Duby: Anti-diabetic, anti-tyrosinase, and anti-inflammatory activity
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2018.01.171openalex-snapshot
A novel IgG1 monoclonal antibody against xanthine oxidase alleviates inflammation induced by potassium oxonate in mice
inferred← citeshttps://doi.org/10.1016/j.inoche.2024.112572openalex-snapshot
Investigating the potential of graphene and nitrogen carbide nanosheets as efficient sensors for drug detection through theoretical analysis
inferred← citeshttps://doi.org/10.1016/j.intimp.2003.10.004openalex-snapshot
Antioxidant activity and inhibitory effects of hydralazine on inducible NOS/COX-2 gene and protein expression in rat peritoneal macrophages
inferred← citeshttps://doi.org/10.1016/j.jbiotec.2008.07.543openalex-snapshot
Xanthine oxidase inhibition by flavones: A drug therapy for gout
inferred← citeshttps://doi.org/10.1016/j.jchromb.2016.02.004openalex-snapshot
Discovery of active components in herbs using chromatographic separation coupled with online bioassay
inferred← citeshttps://doi.org/10.1016/j.jep.2008.02.031openalex-snapshot
Pharmacological basis for use of Pistacia integerrima leaves in hyperuricemia and gout
inferred← citeshttps://doi.org/10.1016/j.jep.2009.05.018openalex-snapshot
In vitro xanthine oxidase inhibitory activity of the fractions of Erythrina stricta Roxb.
inferred← citeshttps://doi.org/10.1016/j.jep.2010.03.017openalex-snapshot
Analgesic and anti-inflammatory effects of Pistacia integerrima extracts in mice
inferred← citeshttps://doi.org/10.1016/j.jep.2020.113278openalex-snapshot
Ethanol extract of Liriodendron chinense (Hemsl.) Sarg barks attenuates hyperuricemic nephropathy by inhibiting renal fibrosis and inflammation in mice
inferred← citeshttps://doi.org/10.1016/j.jep.2021.114490openalex-snapshot
Flower beverages of native medicinal plants from Argentina (Acacia caven, Geoffroea decorticans and Larrea divaricata) as antioxidant and anti-inflammatory
inferred← citeshttps://doi.org/10.1016/j.jff.2011.03.008openalex-snapshot
Antiproliferative potential and DNA scission inhibitory activity of phenolics from whole millet grains
inferred← citeshttps://doi.org/10.1016/j.jff.2021.104698openalex-snapshot
Screening of uric acid-lowering active components of corn silk polysaccharide and its targeted improvement on renal excretory dysfunction in hyperuricemia mice
inferred← citeshttps://doi.org/10.1016/j.jorganchem.2018.01.018openalex-snapshot
Computational exploration of reactive fragment for mechanism-based inhibition of xanthine oxidase
inferred← citeshttps://doi.org/10.1016/j.jpba.2017.11.077openalex-snapshot
Improved bioautographic assay on TLC layers for qualitative and quantitative estimation of xanthine oxidase inhibitors and superoxide scavengers
inferred← citeshttps://doi.org/10.1016/j.jpba.2020.113097openalex-snapshot
On-Flow LC-MS/MS method for screening of xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.jscs.2016.11.004openalex-snapshot
Synthesis and biological evaluation of fluorine substituted pyrazolo[4,3-e][1,2,4]triazines as purine analogues
inferred← citeshttps://doi.org/10.1016/j.mad.2006.12.006openalex-snapshot
Effects of aerobic exercise training on antioxidant enzyme activities and mRNA levels in soleus muscle from young and aged rats
inferred← citeshttps://doi.org/10.1016/j.molstruc.2013.07.043openalex-snapshot
Study on the activity of non-purine xanthine oxidase inhibitor by 3D-QSAR modeling and molecular docking
inferred← citeshttps://doi.org/10.1016/j.molstruc.2015.07.067openalex-snapshot
Synthesis, crystal structures, fluorescence and xanthine oxidase inhibitory activity of pyrazole-based 1,3,4-oxadiazole derivatives
inferred← citeshttps://doi.org/10.1016/j.molstruc.2016.05.055openalex-snapshot
Novel zinc(II)phthalocyanines bearing azo-containing schiff base: Determination of pKa values, absorption, emission, enzyme inhibition and photochemical properties
inferred← citeshttps://doi.org/10.1016/j.molstruc.2019.01.017openalex-snapshot
In silico study of febuxostat analogs as inhibitors of xanthine oxidoreductase: A combined 3D-QSAR and molecular docking study
inferred← citeshttps://doi.org/10.1016/j.molstruc.2019.02.063openalex-snapshot
New 2-hydroxyethyl substituted N-Heterocyclic carbene precursors: Synthesis, characterization, crystal structure and inhibitory properties against carbonic anhydrase and xanthine oxidase
inferred← citeshttps://doi.org/10.1016/j.molstruc.2020.128475openalex-snapshot
Insights from multispectral and molecular docking investigation on the xanthine oxidase inhibition by 1,4-dicaffeoylquinic acid
inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.140395openalex-snapshot
Integrative computational approach for hyperuricemia treatment: 3D QSAR, molecular docking and dynamics of flavonoid analogues as xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.molstruc.2026.147053openalex-snapshot
Xanthine oxidase inhibitory activity of corn by-product flavonoids: enzyme kinetics and computational insights into site-specific inhibition mechanisms
inferred← citeshttps://doi.org/10.1016/j.pathophys.2006.05.002openalex-snapshot
Oxidative stress and atherosclerosis
inferred← citeshttps://doi.org/10.1016/j.procbio.2016.05.014openalex-snapshot
Biophysical analysis of novel oxy-diester hybrid cationic gemini surfactants (C m -E2O-C m ) with xanthine oxidase (XO)
inferred← citeshttps://doi.org/10.1016/j.procbio.2020.06.024openalex-snapshot
Inhibition of xanthine oxidase by theaflavin: Possible mechanism for anti-hyperuricaemia effect in mice
inferred← citeshttps://doi.org/10.1016/j.psj.2019.11.064openalex-snapshot
Goose astrovirus infection affects uric acid production and excretion in goslings
inferred← citeshttps://doi.org/10.1016/j.resp.2011.03.004openalex-snapshot
Airway inflammation and hypersensitivity induced by chronic smoking
inferred← citeshttps://doi.org/10.1016/j.saa.2015.05.056openalex-snapshot
Conformational alterations induced by novel green 16-E2-16 gemini surfactant in xanthine oxidase: Biophysical insights from tensiometry, spectroscopy, microscopy and molecular modeling
inferred← citeshttps://doi.org/10.1016/j.tifs.2025.104939openalex-snapshot
Vine tea (Ampelopsis grossedentata) — A different kind of tea hidden deep in the mountains of China: A comprehensive review of the nutritional profile, functional effect, and diverse applications as a novel raw material in food practices
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2005.11.010openalex-snapshot
Activation of JNK and xanthine oxidase by TNF-α impairs nitric oxide-mediated dilation of coronary arterioles
inferred← citeshttps://doi.org/10.1016/s0960-894x(03)00494-3openalex-snapshot
Novel 3-O-acyl mesquitol analogues as free-Radical scavengers and enzyme inhibitors: synthesis, biological evaluation and structure–activity relationship
inferred← citeshttps://doi.org/10.1016/s2221-6189(13)60029-3openalex-snapshot
Inhibitory activity of xanthine oxidase by fractions Crateva adansonii
inferred← citeshttps://doi.org/10.1017/s1464793103006213openalex-snapshot
Aging in vertebrates, and the effect of caloric restriction: a mitochondrial free radical production–DNA damage mechanism?
inferred← citeshttps://doi.org/10.1021/ac900201gopenalex-snapshot
Simultaneous Electrochemical Monitoring of Metabolites Related to the Xanthine Oxidase Pathway Using a Grinded Carbon Electrode
inferred← citeshttps://doi.org/10.1021/acs.inorgchem.6b02846openalex-snapshot
Protonation and Sulfido versus Oxo Ligation Changes at the Molybdenum Cofactor in Xanthine Dehydrogenase (XDH) Variants Studied by X-ray Absorption Spectroscopy
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5c02404openalex-snapshot
Novel Isoidide Subunit-Containing Xanthine Oxidase Inhibitors with Potent Hypouricemic Effects
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.2c00531openalex-snapshot
Hypouricemic Actions of the Pericarp of Mangosteen in Vitro and in Vivo
inferred← citeshttps://doi.org/10.1021/acs.joc.4c02646openalex-snapshot
Xanthine Nucleosides with Pyrazolo[3,4-d]pyrimidine Skeleton: Functionalization with Halogen Atoms, Clickable Side Chains, Pyrene, and iEDDA Cycloadducts, and Impact of Ionic Forms on Photophysical Properties
inferred← citeshttps://doi.org/10.1021/acs.jpcb.5b01742openalex-snapshot
Physicochemical Characterization of 2-Hydroxybenzophenone with β-Cyclodextrin in Solution and Solid State
inferred← citeshttps://doi.org/10.1021/acsomega.6c08309openalex-snapshot
Electronic-Structure Determinants of Flavonoid Inhibition at the Molybdenum Cofactor of Xanthine Oxidase: A QM/MM Study
inferred← citeshttps://doi.org/10.1021/acsomega.8b03060openalex-snapshot
Knoevenagel/Tandem Knoevenagel and Michael Adducts of Cyclohexane-1,3-dione and Aryl Aldehydes: Synthesis, DFT Studies, Xanthine Oxidase Inhibitory Potential, and Molecular Modeling
inferred← citeshttps://doi.org/10.1021/bc200449kopenalex-snapshot
Scavenging ROS: Superoxide Dismutase/Catalase Mimetics by the Use of an Oxidation-Sensitive Nanocarrier/Enzyme Conjugate
inferred← citeshttps://doi.org/10.1021/ja037940eopenalex-snapshot
Protein Film Voltammetry ofRhodobacterCapsulatusXanthine Dehydrogenase
inferred← citeshttps://doi.org/10.1021/jf0490293openalex-snapshot
Antioxidative, Antimutagenic, and Anticarcinogenic Activities of Rice Bran Extracts in Chemical and Cell Assays
inferred← citeshttps://doi.org/10.1021/jf050716jopenalex-snapshot
Xanthine Oxidase Activity in Vitro: Effects of Food Extracts and Components
inferred← citeshttps://doi.org/10.1021/jf072119yopenalex-snapshot
New C-Deoxyhexosyl Flavones and Antioxidant Properties of Passiflora edulis Leaf Extract
inferred← citeshttps://doi.org/10.1021/jf200485kopenalex-snapshot
Neonicotinoid Insecticides: Oxidative Stress in Planta and Metallo-oxidase Inhibition
inferred← citeshttps://doi.org/10.1021/jf803831vopenalex-snapshot
Pieris brassicae Inhibits Xanthine Oxidase
inferred← citeshttps://doi.org/10.1021/jp307374zopenalex-snapshot
Catalytic Electrochemistry of Xanthine Dehydrogenase
inferred← citeshttps://doi.org/10.1021/jp9041809openalex-snapshot
Theoretical Study of the Mechanism of Inhibition of Xanthine Oxydase by Flavonoids and Gallic Acid Derivatives
inferred← citeshttps://doi.org/10.1021/np060038aopenalex-snapshot
An Apigenin-Derived Xanthine Oxidase Inhibitor from Palhinhaea cernua
inferred← citeshttps://doi.org/10.1021/np500320gopenalex-snapshot
X-ray Crystal Structure of a Xanthine Oxidase Complex with the Flavonoid Inhibitor Quercetin
inferred← citeshttps://doi.org/10.1021/tx800076copenalex-snapshot
Role of the Nitro Functionality in the DNA Binding of 3-Nitro-10-methylbenzothiazolo[3,2-a]quinolinium Chloride
inferred← citeshttps://doi.org/10.1023/b:appt.0000025812.45382.4dopenalex-snapshot
Intestinal ischemic preconditioning: Less xanthine accumulation relates with less apoptosis
inferred← citeshttps://doi.org/10.1023/b:mcbi.0000049134.69131.89openalex-snapshot
Role of oxygen radicals in DNA damage and cancer incidence
inferred← citeshttps://doi.org/10.1038/ja.2008.16openalex-snapshot
Microbial drug discovery: 80 years of progress
inferred← citeshttps://doi.org/10.1038/jid.2014.93openalex-snapshot
Nonmetal Haptens Induce ATP Release from Keratinocytes through Opening of Pannexin Hemichannels by Reactive Oxygen Species
inferred← citeshttps://doi.org/10.1038/nrd2132openalex-snapshot
Drugs, their targets and the nature and number of drug targets
inferred← citeshttps://doi.org/10.1039/b717172bopenalex-snapshot
Biologically relevant O,S-donor compounds. Synthesis, molybdenum complexation and xanthine oxidase inhibition
inferred← citeshttps://doi.org/10.1039/b9nj00736aopenalex-snapshot
Design and synthesis of water soluble (metallo)porphyrins with pendant arms: studies of binding to xanthine oxidase
inferred← citeshttps://doi.org/10.1039/c6fo00822dopenalex-snapshot
Hypouricemic effects of Mesona procumbens Hemsl. through modulating xanthine oxidase activity in vitro and in vivo
inferred← citeshttps://doi.org/10.1039/c6ra24396gopenalex-snapshot
Exploring the interaction between Salvia miltiorrhiza and xanthine oxidase: insights from computational analysis and experimental studies combined with enzyme channel blocking
inferred← citeshttps://doi.org/10.1039/c8md00512eopenalex-snapshot
Benzoflavone derivatives as potent antihyperuricemic agents
inferred← citeshttps://doi.org/10.1039/d1nj02938jopenalex-snapshot
Bioinformatic insights into the biochemical efficacy of a fungal metabolite: asperyellone
inferred← citeshttps://doi.org/10.1039/d1ra06948aopenalex-snapshot
A theoretical study of allopurinol drug sensing by carbon and boron nitride nanostructures: DFT, QTAIM, RDG, NBO and PCM insights
inferred← citeshttps://doi.org/10.1039/d2ra04266eopenalex-snapshot
Tetrabutylammonium bromide-based hydrophobic deep eutectic solvent for the extraction and separation of dihydromyricetin from vine tea and its inhibitory efficiency against xanthine oxidase
inferred← citeshttps://doi.org/10.1039/d2ra06997kopenalex-snapshot
Unveiling the inhibitory mechanism of aureusidin targeting xanthine oxidase by multi-spectroscopic methods and molecular simulations
inferred← citeshttps://doi.org/10.1039/d4md00072bopenalex-snapshot
Heterocyclic compounds as xanthine oxidase inhibitors for the management of hyperuricemia: synthetic strategies, structure–activity relationship and molecular docking studies (2018–2024)
inferred← citeshttps://doi.org/10.1074/jbc.m110.156034openalex-snapshot
Structural and Mechanistic Studies on Klebsiella pneumoniae 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline Decarboxylase
inferred← citeshttps://doi.org/10.1074/jbc.m510692200openalex-snapshot
Exopolysaccharides from Burkholderia cenocepacia Inhibit Neutrophil Chemotaxis and Scavenge Reactive Oxygen Species
inferred← citeshttps://doi.org/10.1080/00071668.2021.1998365openalex-snapshot
Therapeutic antigout and antioxidant activity of Piper betle L. in gout-induced broilers
inferred← citeshttps://doi.org/10.1080/00071668.2026.2728724openalex-snapshot
Molecular modelling study on Piper betle phytocompounds to discover the potential active moiety responsible for xanthine oxidase inhibition in avian gout
inferred← citeshttps://doi.org/10.1080/00387010903185538openalex-snapshot
Indirect Sequential Injection Enzymatic Determination of Allopurinol in Pharmaceuticals Based on Xanthine Oxidase Inhibition
inferred← citeshttps://doi.org/10.1080/03602532.2021.1923728openalex-snapshot
Recent developments in predicting CYP-independent metabolism
inferred← citeshttps://doi.org/10.1080/10426507.2015.1085047openalex-snapshot
Synthesis, Crystal Structures, Fluorescence and Xanthine Oxidase Inhibitory of Sulfur-Containing Pyrazole Derivatives Incorporated with Oxadiazole and Triazole
inferred← citeshttps://doi.org/10.1080/10426507.2020.1756290openalex-snapshot
Synthetic access of new 6-purineselenyl and 8-(1,3,4-thiadiazolyl)-7-benzyl-1, 3-dimethyl-1H-purine-2,6-(3H,7H)-dione derivatives
inferred← citeshttps://doi.org/10.1080/10715760500250083openalex-snapshot
Suppression of oxidative stress in aging NZB/NZW mice: Effect of fish oil feeding on hepatic antioxidant status and guanidino compounds
inferred← citeshttps://doi.org/10.1080/10942912.2016.1177543openalex-snapshot
Antioxidative and xanthine oxidase inhibitory activities and phytochemical screening of the hydro-alcoholic extract of mace, aril of Myristica fragrans: Implication as an adjuvant therapy in gout
inferred← citeshttps://doi.org/10.1080/13543776.2017.1261111openalex-snapshot
An updated patent review: xanthine oxidase inhibitors for the treatment of hyperuricemia and gout (2011-2015)
inferred← citeshttps://doi.org/10.1080/13543776.2020.1811233openalex-snapshot
Xanthine oxidase inhibitors: patent landscape and clinical development (2015–2020)
inferred← citeshttps://doi.org/10.1080/13880209.2017.1377736openalex-snapshot
Comparative effects of green and black tea extracts on lowering serum uric acid in hyperuricemic mice
inferred← citeshttps://doi.org/10.1080/13880209.2021.1878235openalex-snapshot
Effects of epigallocatechin-3-gallate combined with ascorbic acid and glycerol on the stability and uric acid-lowering activity of epigallocatechin-3-gallate
inferred← citeshttps://doi.org/10.1080/14756366.2017.1347165openalex-snapshot
Kinetic study on the inhibition of xanthine oxidase by acylated derivatives of flavonoids synthesised enzymatically
inferred← citeshttps://doi.org/10.1080/14767050500127716openalex-snapshot
Transplacental effects of allopurinol on suppression of oxygen free radical production in chronically instrumented fetal lamb brains during intermittent umbilical cord occlusion
inferred← citeshttps://doi.org/10.1080/14786419.2011.652960openalex-snapshot
A new lupane triterpene from Tetracera scandens L., xanthine oxidase inhibitor
inferred← citeshttps://doi.org/10.1080/17568919.2024.2435254openalex-snapshot
Organoselenium compounds beyond antioxidants
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