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Inducing the Alternative Oxidase Forms Part of the Molecular Strategy of Anoxic Survival in Freshwater Bivalves

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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The anaerobic oyster heart: Coupling of glucose and aspartate fermentation
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Antioxidant enzymes in the digestive gland of the common mussel Mytilus edulis
inferredcites →https://doi.org/10.1007/bf02482839openalex-snapshot
Glycogen degradation and end products of anaerobic metabolism in the fresh water bivalveAnodonta cygnea
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Physiological and metabolic responses to hypoxia in invertebrates
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Cell turnover in tissues of the long-lived ocean quahog Arctica islandica and the short-lived scallop Aequipecten opercularis
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Anaerobic metabolism in bivalvia (Mollusca) Characteristics of anaerobic metabolism
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Organ specific changes in energy metabolism due to anaerobiosis in the sea mussel Mytilus edulis (L.)
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Aspects of anaerobic metabolism in Anodonta cygnea L.
inferredcites →https://doi.org/10.1016/0305-0491(85)90210-xopenalex-snapshot
Excretion of volatile fatty acids by anoxic Mytilus edulis and Anodonta cygnea
inferredcites →https://doi.org/10.1016/0305-0491(94)00132-eopenalex-snapshot
Energy metabolism of the mussel, Mytilus galloprovincialis, during long-term anoxia
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Metabolic and physiological responses in tissues of the long-lived bivalve Arctica islandica to oxygen deficiency
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Role of redox metabolism for adaptation of aquatic animals to drastic changes in oxygen availability
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Epitoky in Nereis (Neanthes) virens (Polychaeta: Nereididae): A story about sex and death
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Anaerobic metabolic patterns related to stress responses in hypoxia exposed mussels Mytilus galloprovincialis
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Molecular and cellular response to short-term oxygen variations in the Pacific oyster Crassostrea gigas
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Geographic variations in shell growth rates of the mussel Diplodon chilensis from temperate lakes of Chile: Implications for biodiversity conservation
inferredcites →https://doi.org/10.1016/j.limno.2011.04.004openalex-snapshot
Effects of sewage pollution and bacterial load on growth and oxidative balance in the freshwater mussel Diplodon chilensis
inferredcites →https://doi.org/10.1016/j.limno.2013.06.004openalex-snapshot
Growth, abundance, morphometric and metabolic parameters of three populations of Diplodon chilensis subject to different levels of natural and anthropogenic organic matter input in a glaciar lake of North Patagonia
inferredcites →https://doi.org/10.1016/j.marenvres.2013.09.007openalex-snapshot
Oxygen radical formation in anoxic transgression and anoxia-reoxygenation: Foe or phantom? Experiments with a hypoxia tolerant bivalve
inferredcites →https://doi.org/10.1016/j.scitotenv.2004.05.020openalex-snapshot
Silver contamination on abiotic and biotic compartments of Nahuel Huapi National Park lakes, Patagonia, Argentina
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Antioxidant defenses and lipid peroxidation during anoxia stress and aerobic recovery in the marine gastropod Littorina littorea
inferredcites →https://doi.org/10.1016/s0022-0981(99)00103-3openalex-snapshot
The effect of prolonged anoxia on enzyme activities in oysters (Crassostrea virginica) at different seasons
inferredcites →https://doi.org/10.1016/s0076-6879(84)05016-3openalex-snapshot
[13] Catalase in vitro
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A Profile of the Metabolic Responses to Anoxia in Marine Invertebrates
inferredcites →https://doi.org/10.1029/2006eo320001openalex-snapshot
Lake Erie hypoxia prompts Canada‐U.S. study
inferredcites →https://doi.org/10.1038/nbt.1883openalex-snapshot
Full-length transcriptome assembly from RNA-Seq data without a reference genome
inferredcites →https://doi.org/10.1038/s41598-017-10976-wopenalex-snapshot
A novel and stress adaptive alternative oxidase derived from alternative splicing of duplicated exon in oyster Crassostrea virginica
inferredcites →https://doi.org/10.1071/mf9890491openalex-snapshot
Effects of Hypoxia on Oxygen consumption by two species of Freshwater Mussel (Unionacea: Hyriidae) from the River Murray
inferredcites →https://doi.org/10.1073/pnas.93.18.9493openalex-snapshot
Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack.
inferredcites →https://doi.org/10.1086/416717openalex-snapshot
Metabolic Rate Depression and Biochemical Adaptation in Anaerobiosis, Hibernation and Estivation
inferredcites →https://doi.org/10.1093/bioinformatics/btn523openalex-snapshot
QGene 4.0, an extensible Java QTL-analysis platform
inferredcites →https://doi.org/10.1098/rstb.2002.1182openalex-snapshot
Biochemical and evolutionary aspects of anaerobically functioning mitochondria
inferredcites →https://doi.org/10.1111/j.1742-4658.2005.04960.xopenalex-snapshot
Response of the Pacific oyster Crassostrea gigas to hypoxia exposure under experimental conditions
inferredcites →https://doi.org/10.1126/science.1156401openalex-snapshot
Spreading Dead Zones and Consequences for Marine Ecosystems
inferredcites →https://doi.org/10.1146/annurev.physiol.69.031905.162529openalex-snapshot
Hypoxia Tolerance in Reptiles, Amphibians, and Fishes: Life with Variable Oxygen Availability
inferredcites →https://doi.org/10.1159/000345331openalex-snapshot
Environmental Control and Control of the Environment: The Basis of Longevity in Bivalves
inferredcites →https://doi.org/10.1242/jeb.032151openalex-snapshot
Alternative oxidase in animals: unique characteristics and taxonomic distribution
inferredcites →https://doi.org/10.1242/jeb.055178openalex-snapshot
Physiological responses to self-induced burrowing and metabolic rate depression in the ocean quahogArctica islandica
inferredcites →https://doi.org/10.1242/jeb.081984openalex-snapshot
The physiological response of the marine platyhelminthMacrostomum lignanoto different environmental oxygen concentrations
inferredcites →https://doi.org/10.1242/jeb.134700openalex-snapshot
Intermittent hypoxia leads to functional reorganization of mitochondria and affects cellular bioenergetics in marine molluscs
inferredcites →https://doi.org/10.1242/jeb.203.21.3355openalex-snapshot
Mitochondrial Oxyconformity and Cold Adaptation in the Polychaete Nereis Pelagica and the Bivalve Arctica Islandica From The Baltic And White Seas
inferredcites →https://doi.org/10.1371/journal.pone.0044621openalex-snapshot
Gene Expression and Physiological Changes of Different Populations of the Long-Lived Bivalve Arctica islandica under Low Oxygen Conditions
inferredcites →https://doi.org/10.17161/to.v0i0.6583openalex-snapshot
Treatise Online no. 92: Part N, Revised, Volume 1, Chapter 7: Ecophysiology of extant marine Bivalvia
inferredcites →https://doi.org/10.2307/1540740openalex-snapshot
BODY FLUID COMPOSITION AND AERIAL OXYGEN CONSUMPTION IN THE FRESHWATER MUSSEL, LIGUMIA SUBROSTRATA (SAY): EFFECTS OF DEHYDRATION AND ANOXIC STRESS
inferredcites →https://doi.org/10.3354/dao02384openalex-snapshot
Disseminated neoplasia in cockles Cerastoderma edule: ultrastructural characterisation and effects on haemolymph cell parameters
inferredcites →https://doi.org/10.3354/meps166017openalex-snapshot
Ecosystem responses to internal and watershed organic matter loading:consequences for hypoxia in the eutrophying Neuse River Estuary, North Carolina, USA
inferredcites →https://doi.org/10.4067/s0718-19572008000300012openalex-snapshot
Caracterización metabólica de Diplodon chilensis (Gray, 1828) (Bivalvia: Hyriidae) expuesto a anoxia experimental
inferredcites →https://doi.org/10.5194/bg-6-2063-2009openalex-snapshot
Effects of natural and human-induced hypoxia on coastal benthos

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4872617openalex-extracted
Effects of Water Temperature Increase on Transcriptomic, Biochemical, and Histopathological Responses of the Bivalve Species Mytilus Galloprovincialis to the Antineoplastic Drug 5-Fluorouracil
inferred← citeshttps://doi.org/10.1007/s00227-025-04634-3openalex-snapshot
Anthropogenic low-frequency sound effects on resting metabolism and energy pathways in two marine benthic crustaceans
inferred← citeshttps://doi.org/10.1007/s00360-026-01667-yopenalex-snapshot
Energy metabolism and adenylate system in Mytilus galloprovincialis (Lamarck, 1819) tissues under acute hypoxia
inferred← citeshttps://doi.org/10.1007/s10452-025-10244-4openalex-snapshot
Microbial community of respiratory surfaces and features of tissue energy metabolism in the Black Sea bivalve mollusk Anadara kagoshimensis (Tokunaga, 1906) under conditions of acute hypoxia and hydrogen sulfide contamination
inferred← citeshttps://doi.org/10.1007/s10499-025-01959-0openalex-snapshot
A common garden comparison of the microbiome and gene expression of intertidally- and subtidally-cultured Pacific oysters (Crassostrea gigas) in relation to extreme warming events
inferred← citeshttps://doi.org/10.1007/s11033-019-04879-4openalex-snapshot
The transcriptomic responses of the ark shell, Anadara broughtonii, to sulfide and hypoxia exposure
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2024.741462openalex-snapshot
Survival and physiological responses of pearl oyster Pinctada maxima seedlings: Comparative analysis of wet (submerged) and dry (waterless) transportation methods
inferred← citeshttps://doi.org/10.1016/j.aquatox.2021.105996openalex-snapshot
The critical roles of mitochondrial alternative chains in juvenile ark shells (Anadara broughtonii) exposed to acute hypoxia with or without sulfide
inferred← citeshttps://doi.org/10.1016/j.aquatox.2023.106586openalex-snapshot
Dreissena polymorpha responses under thermal and hypoxic stress: New insights in the tolerance of this freshwater sentinel species
inferred← citeshttps://doi.org/10.1016/j.bbabio.2022.148556openalex-snapshot
What physiological role(s) does the alternative oxidase perform in animals?
inferred← citeshttps://doi.org/10.1016/j.bbadis.2018.10.012openalex-snapshot
Alternative respiratory chain enzymes: Therapeutic potential and possible pitfalls
inferred← citeshttps://doi.org/10.1016/j.cbd.2024.101215openalex-snapshot
Transcriptional and physiological profiles reveal the respiratory, antioxidant and metabolic adaption to intermittent hypoxia in the clam Tegillarca granosa
inferred← citeshttps://doi.org/10.1016/j.cbpa.2026.112078openalex-snapshot
Physiological and bioenergetic responses of the undulated surf clam Paphia undulata to rapid salinity change
inferred← citeshttps://doi.org/10.1016/j.cbpb.2018.11.003openalex-snapshot
Identification of the alternative oxidase gene and its expression in the copepod Tigriopus californicus
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2020.110341openalex-snapshot
In situ experiment to evaluate biochemical responses in the freshwater mussel Diplodon chilensis under anthropogenic eutrophication conditions
inferred← citeshttps://doi.org/10.1016/j.jembe.2018.10.005openalex-snapshot
Multi-level responses of Macoma balthica to recurring hypoxic disturbance
inferred← citeshttps://doi.org/10.1016/j.jenvman.2022.115535openalex-snapshot
The impact of iron coagulant on the behavior and biochemistry of freshwater mussels Anodonta cygnea and Unio tumidus during lake restoration
inferred← citeshttps://doi.org/10.1016/j.jtherbio.2023.103776openalex-snapshot
Hiding from heat: The transcriptomic response of two clam species is modulated by behaviour and habitat
inferred← citeshttps://doi.org/10.1016/j.marenvres.2021.105326openalex-snapshot
Two-sided effects of prolonged hypoxia and sulfide exposure on juvenile ark shells (Anadara broughtonii)
inferred← citeshttps://doi.org/10.1016/j.ocecoaman.2026.108176openalex-snapshot
Mitigation of sulfide stress on eelgrass Zostera marina and Manila clam Ruditapes philippinarum through an eelgrass–clam coculture system
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2025.179947openalex-snapshot
Effects of water temperature increase on gene expression, biochemical, and histopathological responses of the bivalve species Mytilus galloprovincialis to the antineoplastic drug 5-fluorouracil
inferred← citeshttps://doi.org/10.1021/acsomega.3c09339openalex-snapshot
Alternative Oxidase: From Molecule and Function to Future Inhibitors
inferred← citeshttps://doi.org/10.1038/s41598-025-05927-9openalex-snapshot
The effects of potassium cyanide on tardigrade Paramacrobiotus experimentalis
inferred← citeshttps://doi.org/10.1080/10236244.2020.1867477openalex-snapshot
Acclimatization in the bay scallop Argopecten irradians along a eutrophication gradient: insights from heartbeat rate measurements during a simulated hypoxic event
inferred← citeshttps://doi.org/10.1093/icb/icab057openalex-snapshot
Bivalve Molluscs as Model Systems for Studying Mitochondrial Biology
inferred← citeshttps://doi.org/10.1093/icb/icz047openalex-snapshot
Mitochondrial Mechanisms Underlying Tolerance to Fluctuating Oxygen Conditions: Lessons from Hypoxia-Tolerant Organisms
inferred← citeshttps://doi.org/10.1093/jxb/eraf021openalex-snapshot
The role of alternative oxidase in the maintenance of cellular redox balance under hypoxia via participation in nitric oxide turnover
inferred← citeshttps://doi.org/10.1134/s1063074024700445openalex-snapshot
The Effect of Acute Hypoxia and Hydrogen Sulfide Contamination on Succinate Dehydrogenase Activity and the Adenylate Complex in Tissues in the Bivalve Mollusk Anadara kagoshimensis (Tokunaga, 1906)
inferred← citeshttps://doi.org/10.1134/s1995082922050194openalex-snapshot
Effect of Hydrogen Sulfide Loading on the Activity of Energy Metabolism Enzymes and the Adenylate System in Tissues of the Anadara kagoshimensis Clam
inferred← citeshttps://doi.org/10.1134/s2075111723030074openalex-snapshot
Effect of Salinity on the Oxidoreductase Activity in Tissues of the Ark Clam Anadara kagoshimensis (Tokunaga, 1906), a Black Sea Invader
inferred← citeshttps://doi.org/10.1139/cjz-2020-0115openalex-snapshot
Biochemical adaptations of the stout razor clam (Tagelus plebeius) to changes in oxygen availability: resilience in a changing world?
inferred← citeshttps://doi.org/10.1186/s13071-022-05227-5openalex-snapshot
The identification of alternative oxidase in intermediate host snails of Schistosoma and its potential role in protecting Oncomelania hupensis against niclosamide-induced stress
inferred← citeshttps://doi.org/10.1186/s13071-022-05642-8openalex-snapshot
Inhibition of alternative oxidase disrupts the development and oviposition of Biomphalaria glabrata snails
inferred← citeshttps://doi.org/10.1242/jeb.233932openalex-snapshot
Repeat exposure to hypercapnic seawater modifies growth and oxidative status in a tolerant burrowing clam
inferred← citeshttps://doi.org/10.1242/jeb.242985openalex-snapshot
The alternative oxidase (AOX) increases sulphide tolerance in the highly invasive marine invertebrateCiona intestinalis
inferred← citeshttps://doi.org/10.1242/jeb.252244openalex-snapshot
An ancient oxidase lost in vertebrates promotes extreme stress tolerance in an emerging cnidarian model for ecology, evolution and biomedicine
inferred← citeshttps://doi.org/10.1371/journal.pone.0244260openalex-snapshot
The tardigrade Hypsibius exemplaris has the active mitochondrial alternative oxidase that could be studied at animal organismal level
inferred← citeshttps://doi.org/10.21203/rs.3.rs-60975/v1openalex-snapshot
The Tardigrade Hypsibius Exemplaris as an Emerging Model to Study the Mitochondrial Alternative Oxidase at Animal Organismal Level
inferred← citeshttps://doi.org/10.3389/fphys.2020.00248openalex-snapshot
Hypoxia Tolerance of 10 Euphausiid Species in Relation to Vertical Temperature and Oxygen Gradients
inferred← citeshttps://doi.org/10.3389/fphys.2023.1083240openalex-snapshot
A molecular perspective on the invasibility of the southern ocean benthos: The impact of hypoxia and temperature on gene expression in South American and Antarctic Aequiyoldia bivalves
inferred← citeshttps://doi.org/10.3389/fphys.2026.1932200openalex-snapshot
Comparative analysis of bioenergetic pathways in Medusozoa based on integrated genomic, transcriptomic and proteomic data
inferred← citeshttps://doi.org/10.3390/antiox13091063openalex-snapshot
Antioxidant Capacity, Enzyme Activities Related to Energy Metabolism, and Transcriptome Analysis of Crassostrea hongkongensis Exposed to Hypoxia
inferred← citeshttps://doi.org/10.6084/m9.figshare.26569525openalex-snapshot
Additional file 1 of Inhibition of alternative oxidase disrupts the development and oviposition of Biomphalaria glabrata snails
inferred← citeshttps://doi.org/10.6084/m9.figshare.26569528openalex-snapshot
Additional file 2 of Inhibition of alternative oxidase disrupts the development and oviposition of Biomphalaria glabrata snails
inferred← citeshttps://doi.org/10.6084/m9.figshare.26569531openalex-snapshot
Additional file 3 of Inhibition of alternative oxidase disrupts the development and oviposition of Biomphalaria glabrata snails
inferred← citeshttps://doi.org/10.70675/20512ee3z0d60z4026zae5cz53d577d4239bopenalex-snapshot
MÉtabolisme ENergétique : synthèse et gestion de l’énergie cellulaire chez la moule d’eau douce DREissena polymorpha
inferred← citeshttps://doi.org/10.70675/f6b4bd3ez1a31z4703zbd85zc43b6c797692openalex-snapshot
Bioaccumulation et voies de toxicité de la carbamazépine et du mercure chez la moule zébrée Dreissena polymorpha
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