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“Cell Membrane Theory of Senescence” and the Role of Bioactive Lipids in Aging, and Aging Associated Diseases and Their Therapeutic Implications

https://doi.org/10.3390/biom11020241

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Essential fatty acids: biochemistry, physiology and pathology

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Docosahexaenoic acid attenuates adipose tissue angiogenesis and insulin resistance in high fat diet‐fed middle‐aged mice via a sirt1‐dependent mechanism

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Human Mesenchymal Stem/Stromal Cells Cultured as Spheroids are Self‐activated to Produce Prostaglandin E2 that Directs Stimulated Macrophages into an Anti‐inflammatory Phenotype

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Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses

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Linoleic Acid Metabolism in Primary Cultures of Adult Rat Cardiomyocytes Is Impaired by Aging

inferredcites →https://doi.org/10.1006/bbrc.2000.3779openalex-snapshot

Prostaglandin E2 Receptors, EP2 and EP4, Differentially Modulate TNF-α and IL-6 Production Induced by Lipopolysaccharide in Mouse Peritoneal Neutrophils

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Cytosolic Phospholipase A2(cPLA2) Immunoreactivity Is Elevated in Alzheimer's Disease Brain

inferredcites →https://doi.org/10.1007/978-1-0716-0741-1openalex-snapshot

Molecular Biochemical Aspects of Cancer

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A Perinatal Strategy For Preventing Adult Disease: The Role Of Long-Chain Polyunsaturated Fatty Acids

inferredcites →https://doi.org/10.1007/978-3-030-42667-5_3openalex-snapshot

Bioactive Lipids in Age-Related Disorders

inferredcites →https://doi.org/10.1007/978-94-007-0495-4openalex-snapshot

Molecular Basis of Health and Disease

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Unsaturated free fatty acids inactivate animal enveloped viruses

inferredcites →https://doi.org/10.1007/bf02533988openalex-snapshot

Effects of aging on the composition and metabolism of docosahexaenoate‐containing lipids of retina

inferredcites →https://doi.org/10.1007/bf02535837openalex-snapshot

Effect of ethanol administration on fatty acid desaturation

inferredcites →https://doi.org/10.1007/bf03327396openalex-snapshot

Effects of dietary restriction on age-related changes in the phospholipid fatty acid composition of various rat tissues

inferredcites →https://doi.org/10.1007/s00125-006-0383-4openalex-snapshot

Improvements in glucose tolerance and insulin sensitivity after lifestyle intervention are related to changes in serum fatty acid profile and desaturase activities: the SLIM study

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Lithium activates brain phospholipase A2 and improves memory in rats: implications for Alzheimer’s disease

inferredcites →https://doi.org/10.1007/s004180000174openalex-snapshot

Lipids are a constitutive component of cytolytic granules

inferredcites →https://doi.org/10.1007/s00702-006-0585-4openalex-snapshot

Requirement of hippocampal phospholipase A2 activity for long-term memory retrieval in rats

inferredcites →https://doi.org/10.1007/s10753-016-0358-7openalex-snapshot

Gamma-Linolenic Acid Suppresses NF-κΒ Signaling via CD36 in the Lipopolysaccharide-Induced Inflammatory Response in Primary Goat Mammary Gland Epithelial Cells

inferredcites →https://doi.org/10.1007/s10753-018-0819-2openalex-snapshot

Resolvin D1 Promotes SIRT1 Expression to Counteract the Activation of STAT3 and NF-κB in Mice with Septic-Associated Lung Injury

inferredcites →https://doi.org/10.1007/s11064-018-2573-0openalex-snapshot

Localisation of Formyl-Peptide Receptor 2 in the Rat Central Nervous System and Its Role in Axonal and Dendritic Outgrowth

inferredcites →https://doi.org/10.1007/s11745-000-0646-3openalex-snapshot

Fatty acid analysis of blood plasma of patients with alzheimer's disease, other types of dementia, and cognitive impairment

inferredcites →https://doi.org/10.1007/s11745-015-4030-zopenalex-snapshot

Decreases in Phospholipids Containing Adrenic and Arachidonic Acids Occur in the Human Hippocampus over the Adult Lifespan

inferredcites →https://doi.org/10.1007/s11745-997-0055-7openalex-snapshot

The effect of dietary arachidonic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans

inferredcites →https://doi.org/10.1007/s11745-997-0145-6openalex-snapshot

The effect of dietary docosahexaenoic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans

inferredcites →https://doi.org/10.1007/s11745-998-0272-0openalex-snapshot

Changes in tissue polyunsaturated fatty acids with age, in spontaneously hypertensive rats

inferredcites →https://doi.org/10.1007/s12035-017-0413-xopenalex-snapshot

Distribution of Alox15 in the Rat Brain and Its Role in Prefrontal Cortical Resolvin D1 Formation and Spatial Working Memory

inferredcites →https://doi.org/10.1016/0006-291x(87)91281-2openalex-snapshot

Polyunsaturated fatty acids augment free radical generation in tumor cells in vitro

inferredcites →https://doi.org/10.1016/0006-291x(89)92142-6openalex-snapshot

Age-related changes in linoleate and α-linolenate desaturation by rat liver microsomes

inferredcites →https://doi.org/10.1016/0006-2952(95)00156-topenalex-snapshot

Lipocortin-1 and the control of arachidonic acid release in cell signalling

inferredcites →https://doi.org/10.1016/0008-8749(83)90006-0openalex-snapshot

Role of macrophage lipids in regulating tumoricidal activity

inferredcites →https://doi.org/10.1016/0047-6374(80)90109-8openalex-snapshot

Age-dependence of molecular and functional changes in biological membrane properties

inferredcites →https://doi.org/10.1016/0090-6980(85)90216-3openalex-snapshot

Prostaglandins and their precursors can modify genetic damage-induced by gamma-radiation and benzo (a) pyrene

inferredcites →https://doi.org/10.1016/0262-1746(84)90128-8openalex-snapshot

Prostaglandins and mutagenesis: prevention and/or reversibility of genetic damage induced by benzo (a) pyrene in the bone marrow cells of mice by prostaglandin El

inferredcites →https://doi.org/10.1016/0304-3835(91)90008-6openalex-snapshot

Tumoricidal action of cis-unsaturated fatty acids and their relationship to free radicals and lipid peroxidation

inferredcites →https://doi.org/10.1016/0306-4522(89)90162-0openalex-snapshot

Nordihydroguaiaretic acid blocks the synaptic component of long-term potentiation and the associated increases in release of glutamate and arachidonate: An in vivo study in the dentate gyrus of the rat

inferredcites →https://doi.org/10.1016/0891-5849(87)90033-5openalex-snapshot

Uptake and distribution of cis-unsaturated fatty acids and their effect on free radical generation in normal and tumor cells in vitro

inferredcites →https://doi.org/10.1016/0952-3278(91)90038-7openalex-snapshot

Reactive oxygen species, lipid peroxides and essential fatty acids in patients with rheumatoid arthritis and systemic lupus erythematosus

inferredcites →https://doi.org/10.1016/0952-3278(94)90136-8openalex-snapshot

Beneficial effect of eicosapentaenoic and docosahexaenoic acids in the management of systemic lupus erythematosus and its relationship to the cytokine network

inferredcites →https://doi.org/10.1016/0952-3278(94)90242-9openalex-snapshot

Effect of prostaglandins and their precursors on the proliferation of human lymphocytes and their secretion of tumor necrosis factor and various interleukins

inferredcites →https://doi.org/10.1016/0952-3278(95)90066-7openalex-snapshot

Essential fatty acid metabolism in patients with essential hypertension, diabetes mellitus and coronary heart disease

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The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation

inferredcites →https://doi.org/10.1016/j.amjms.2017.06.002openalex-snapshot

Involvement of Resveratrol and ω-3 Polyunsaturated Fatty Acids on Sirtuin 1 Gene Expression in THP1 Cells

inferredcites →https://doi.org/10.1016/j.arcmed.2014.03.008openalex-snapshot

Effects of Fish Oil with a High Content of n-3 Polyunsaturated Fatty Acids on Mouse Gut Microbiota

inferredcites →https://doi.org/10.1016/j.arcmed.2019.05.004openalex-snapshot

Vitamin C for Type 2 Diabetes Mellitus and Hypertension

inferredcites →https://doi.org/10.1016/j.arcmed.2020.03.004openalex-snapshot

Can Bioactive Lipids Inactivate Coronavirus (COVID-19)?

inferredcites →https://doi.org/10.1016/j.arcmed.2020.04.004openalex-snapshot

Response to: Bioactive Lipids and Coronavirus (COVID-19)-further Discussion

inferredcites →https://doi.org/10.1016/j.arcmed.2020.05.002openalex-snapshot

Resolvin D1 Ameliorates Nicotinamide-streptozotocin-induced Type 2 Diabetes Mellitus by its Anti-inflammatory Action and Modulating PI3K/Akt/mTOR Pathway in the Brain

inferredcites →https://doi.org/10.1016/j.arr.2011.01.001openalex-snapshot

Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?

inferredcites →https://doi.org/10.1016/j.bbalip.2017.02.010openalex-snapshot

Omega-3 polyunsaturated fatty acids suppress the inflammatory responses of lipopolysaccharide-stimulated mouse microglia by activating SIRT1 pathways

inferredcites →https://doi.org/10.1016/j.bbr.2015.02.048openalex-snapshot

Docosahexaenoic acid partially ameliorates deficits in social behavior and ultrasonic vocalizations caused by prenatal ethanol exposure

inferredcites →https://doi.org/10.1016/j.bbrc.2013.09.047openalex-snapshot

Elevated COX2 expression and PGE2 production by downregulation of RXRα in senescent macrophages

inferredcites →https://doi.org/10.1016/j.bbrc.2018.03.096openalex-snapshot

Adipose-derived stem cells ameliorate colitis by suppression of inflammasome formation and regulation of M1-macrophage population through prostaglandin E2

inferredcites →https://doi.org/10.1016/j.bcp.2009.11.023openalex-snapshot

Anthrax lethal toxin down-regulates type-IIA secreted phospholipase A2 expression through MAPK/NF-κB inactivation

inferredcites →https://doi.org/10.1016/j.biopha.2018.07.166openalex-snapshot

15-HETE protects pulmonary artery smooth muscle cells against apoptosis via SIRT1 regulation during hypoxia

inferredcites →https://doi.org/10.1016/j.biopsych.2009.02.013openalex-snapshot

Meta-Analysis of Alzheimer's Disease Risk with Obesity, Diabetes, and Related Disorders

inferredcites →https://doi.org/10.1016/j.cell.2005.11.044openalex-snapshot

Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

inferredcites →https://doi.org/10.1016/j.cell.2012.10.047openalex-snapshot

The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism

inferredcites →https://doi.org/10.1016/j.dib.2017.08.009openalex-snapshot

Data on the effect of oral feeding of Arachidonic acid or Docosahexanoic acid on haematopoiesis in mice

inferredcites →https://doi.org/10.1016/j.exger.2005.04.004openalex-snapshot

Aging is characterized by a profound reduction in anti-inflammatory lipoxin A4 levels

inferredcites →https://doi.org/10.1016/j.exger.2007.09.004openalex-snapshot

Membrane phospholipid composition may contribute to exceptional longevity of the naked mole-rat (Heterocephalus glaber): A comparative study using shotgun lipidomics

inferredcites →https://doi.org/10.1016/j.exger.2014.10.015openalex-snapshot

Long-term streptozotocin diabetes impairs arachidonic and docosahexaenoic acid metabolism and ∆5 desaturation indices in aged rats

inferredcites →https://doi.org/10.1016/j.freeradbiomed.2016.01.026openalex-snapshot

Lipoxin A4 attenuates LPS-induced mouse acute lung injury via Nrf2-mediated E-cadherin expression in airway epithelial cells

inferredcites →https://doi.org/10.1016/j.immuni.2014.02.013openalex-snapshot

Targeted Prostaglandin E2 Inhibition Enhances Antiviral Immunity through Induction of Type I Interferon and Apoptosis in Macrophages

inferredcites →https://doi.org/10.1016/j.isci.2019.07.012openalex-snapshot

Mosquito Midgut Prostaglandin Release Establishes Systemic Immune Priming

inferredcites →https://doi.org/10.1016/j.jare.2018.01.001openalex-snapshot

Arachidonic acid and other unsaturated fatty acids and some of their metabolites function as endogenous antimicrobial molecules: A review

inferredcites →https://doi.org/10.1016/j.jare.2018.02.004openalex-snapshot

Ageing: Is there a role for arachidonic acid and other bioactive lipids? A review

inferredcites →https://doi.org/10.1016/j.lfs.2020.117327openalex-snapshot

CYP2J2-produced epoxyeicosatrienoic acids attenuate ischemia/reperfusion-induced acute kidney injury by activating the SIRT1-FoxO3a pathway

inferredcites →https://doi.org/10.1016/j.mehy.2012.12.007openalex-snapshot

Is sepsis a pro-resolution deficiency disorder?

inferredcites →https://doi.org/10.1016/j.mehy.2019.109473openalex-snapshot

Bioactive lipids as modulators of immune check point inhibitors

inferredcites →https://doi.org/10.1016/j.micinf.2006.04.010openalex-snapshot

Human cytomegalovirus induced cyclooxygenase-2 in human retinal pigment epithelial cells augments viral replication through a prostaglandin pathway

inferredcites →https://doi.org/10.1016/j.micinf.2008.08.008openalex-snapshot

Salmonella enterica serovar Enteritidis dam mutant induces low NOS-2 and COX-2 expression in macrophages via attenuation of MAPK and NF-κB pathways

inferredcites →https://doi.org/10.1016/j.micinf.2011.11.004openalex-snapshot

Mycobacterium indicus pranii downregulates MMP-9 and iNOS through COX-2 dependent and TNF-α independent pathway in mouse peritoneal macrophages in vitro

inferredcites →https://doi.org/10.1016/j.molimm.2012.08.014openalex-snapshot

Prostaglandin E2 inhibits IL-23 and IL-12 production by human monocytes through down-regulation of their common p40 subunit

inferredcites →https://doi.org/10.1016/j.molimm.2012.12.010openalex-snapshot

PGE2 differentially regulates monocyte-derived dendritic cell cytokine responses depending on receptor usage (EP2/EP4)

inferredcites →https://doi.org/10.1016/j.neuron.2005.10.028openalex-snapshot

Synaptic Activity Regulates Interstitial Fluid Amyloid-β Levels In Vivo

inferredcites →https://doi.org/10.1016/j.nut.2012.11.013openalex-snapshot

Nutritional factors in the pathobiology of autism

inferredcites →https://doi.org/10.1016/j.nut.2013.01.012openalex-snapshot

Autism as a disorder of deficiency of brain-derived neurotrophic factor and altered metabolism of polyunsaturated fatty acids

inferredcites →https://doi.org/10.1016/j.nut.2014.05.015openalex-snapshot

Sucrose, fructose, glucose, and their link to metabolic syndrome and cancer

inferredcites →https://doi.org/10.1016/j.nut.2016.10.004openalex-snapshot

Arachidonic acid and lipoxinA4 attenuate streptozotocin-induced cytotoxicity to RIN5 F cells in vitro and type 1 and type 2 diabetes mellitus in vivo

inferredcites →https://doi.org/10.1016/j.plefa.2003.09.002openalex-snapshot

Rapid alterations of serum fatty acids with the intravenous administration of an arachidonate solution

inferredcites →https://doi.org/10.1016/j.plefa.2005.11.006openalex-snapshot

Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus

inferredcites →https://doi.org/10.1016/j.plefa.2006.01.002openalex-snapshot

Effect of γ-linolenic acid and prostaglandins E1 on gamma-radiation and chemical-induced genetic damage to the bone marrow cells of mice

inferredcites →https://doi.org/10.1016/j.plefa.2008.11.008openalex-snapshot

Effect of polyunsaturated fatty acids on diphenyl hydantoin-induced genetic damage in vitro and in vivo

inferredcites →https://doi.org/10.1016/j.plefa.2009.05.024openalex-snapshot

Cellular and molecular events mediated by docosahexaenoic acid-derived neuroprotectin D1 signaling in photoreceptor cell survival and brain protection

inferredcites →https://doi.org/10.1016/j.plefa.2012.11.009openalex-snapshot

Arachidonic acid and lipoxin A4 as possible endogenous anti-diabetic molecules

inferredcites →https://doi.org/10.1016/j.plefa.2015.11.005openalex-snapshot

Associations between a fatty acid desaturase gene polymorphism and blood arachidonic acid compositions in Japanese elderly

inferredcites →https://doi.org/10.1016/j.plefa.2019.07.003openalex-snapshot

Aging and FADS1 polymorphisms decrease the biosynthetic capacity of long-chain PUFAs: A human trial using [U-13C]linoleic acid

inferredcites →https://doi.org/10.1016/j.plipres.2013.10.002openalex-snapshot

Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: The influence of LCPUFA on neural development, aging, and neurodegeneration

inferredcites →https://doi.org/10.1016/j.prostaglandins.2009.12.007openalex-snapshot

15-HETE protects rat pulmonary arterial smooth muscle cells from apoptosis via the PI3K/Akt pathway

inferredcites →https://doi.org/10.1016/j.prostaglandins.2011.11.003openalex-snapshot

15-Hydroxyeicosatetraenoic acid (15-HETE) protects pulmonary artery smooth muscle cells from apoptosis via inducible nitric oxide synthase (iNOS) pathway

inferredcites →https://doi.org/10.1016/s0014-5793(02)03481-6openalex-snapshot

Expression and function of phospholipase A2 in brain

inferredcites →https://doi.org/10.1016/s0021-5198(19)30597-9openalex-snapshot

Ca2+-Independent Phospholipase A2 Inhibitor Impairs Spatial Memory of Mice

inferredcites →https://doi.org/10.1016/s0021-9258(17)34154-6openalex-snapshot

Regulation of rat hepatic stearoyl coenzyme A desaturase. The roles of insulin and carbohydrate.

inferredcites →https://doi.org/10.1016/s0022-2275(20)30469-7openalex-snapshot

In vitro mimicry of essential fatty acid deficiency in human endothelial cells by TNFα impact of ω-3 versus ω-6 fatty acids

inferredcites →https://doi.org/10.1016/s0022-2275(20)34276-0openalex-snapshot

Membrane lipid composition and cellular function.

inferredcites →https://doi.org/10.1016/s0024-3205(01)01072-4openalex-snapshot

A long-lasting facilitation of hippocampal neurotransmission via a phospholipase A2 signaling pathway

inferredcites →https://doi.org/10.1016/s0034-8376(25)00202-5openalex-snapshot

Biology of Healthy Aging and Longevity

inferredcites →https://doi.org/10.1016/s0065-2423(05)41006-9openalex-snapshot

Clinical Laboratory Tools to Diagnose Inflammation

inferredcites →https://doi.org/10.1016/s0090-6980(02)00020-5openalex-snapshot

Phospholipase A2 enzymes

inferredcites →https://doi.org/10.1016/s0163-1047(05)80005-6openalex-snapshot

Inhibitors of phospholipase A2 produce amnesia for a passive avoidance task in the chick

inferredcites →https://doi.org/10.1016/s0197-4580(02)00074-xopenalex-snapshot

The role of polyunsaturated fatty acids in restoring the aging neuronal membrane

inferredcites →https://doi.org/10.1016/s0387-7604(02)00221-8openalex-snapshot

Can memory be improved? A discussion on the role of ras, GABA, acetylcholine, NO, insulin, TNF-α, and long-chain polyunsaturated fatty acids in memory formation and consolidation

inferredcites →https://doi.org/10.1016/s0899-9007(00)00468-8openalex-snapshot

Prevention of chemically induced diabetes mellitus in experimental animals by polyunsaturated fatty acids

inferredcites →https://doi.org/10.1016/s0899-9007(02)00840-7openalex-snapshot

Essential fatty acids as possible enhancers of the beneficial actions of probiotics

inferredcites →https://doi.org/10.1016/s0899-9007(02)00852-3openalex-snapshot

Long-chain polyunsaturated fatty acids in the growth and development of the brain and memory

inferredcites →https://doi.org/10.1016/s0899-9007(02)00855-9openalex-snapshot

Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus

inferredcites →https://doi.org/10.1016/s0899-9007(02)00856-0openalex-snapshot

Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus

inferredcites →https://doi.org/10.1016/s0899-9007(03)00174-6openalex-snapshot

Long-chain polyunsaturated fatty acids in memory formation and consolidation:

inferredcites →https://doi.org/10.1016/s0952-3278(97)90533-0openalex-snapshot

Oxidant stress, anti-oxidants and essential fatty acids in systemic lupus erythematosus

inferredcites →https://doi.org/10.1023/a:1021604623208openalex-snapshot

Age-Associated Changes in Central Nervous System Glycerolipid Composition and Metabolism

inferredcites →https://doi.org/10.1038/336068a0openalex-snapshot

NMDA receptors activate the arachidonic acid cascade system in striatal neurons

inferredcites →https://doi.org/10.1038/341739a0openalex-snapshot

Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus

inferredcites →https://doi.org/10.1038/9550openalex-snapshot

Inducible cyclooxygenase may have anti-inflammatory properties

inferredcites →https://doi.org/10.1038/labinvest.2014.161openalex-snapshot

Intracellular colon cancer-associated Escherichia coli promote protumoral activities of human macrophages by inducing sustained COX-2 expression

inferredcites →https://doi.org/10.1038/nature05883openalex-snapshot

Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis

inferredcites →https://doi.org/10.1038/nature10815openalex-snapshot

The sirtuin SIRT6 regulates lifespan in male mice

inferredcites →https://doi.org/10.1038/nature11929openalex-snapshot

Differential stem- and progenitor-cell trafficking by prostaglandin E2

inferredcites →https://doi.org/10.1038/nature23007openalex-snapshot

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

inferredcites →https://doi.org/10.1038/nature24297openalex-snapshot

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

inferredcites →https://doi.org/10.1038/ncomms5172openalex-snapshot

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice

inferredcites →https://doi.org/10.1038/nm.1905openalex-snapshot

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

inferredcites →https://doi.org/10.1038/s41467-019-11978-0openalex-snapshot

Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids

inferredcites →https://doi.org/10.1038/s41575-019-0157-3openalex-snapshot

The role of short-chain fatty acids in microbiota–gut–brain communication

inferredcites →https://doi.org/10.1038/sj.bjp.0703632openalex-snapshot

Cyclo‐oxygenase‐1 and −2 contribution to endothelial dysfunction in ageing

inferredcites →https://doi.org/10.1038/sj.bjp.0705326openalex-snapshot

Docosahexaenoic acid and arachidonic acid release in rat brain astrocytes is mediated by two separate isoforms of phospholipase A2 and is differently regulated by cyclic AMP and Ca2+

inferredcites →https://doi.org/10.1038/srep38308openalex-snapshot

Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism

inferredcites →https://doi.org/10.1042/bsr20192117openalex-snapshot

Bioactive lipids in intervertebral disc degeneration and its therapeutic implications

inferredcites →https://doi.org/10.1046/j.1365-2567.2002.01474.xopenalex-snapshot

The modulatory effects of prostaglandin‐E on cytokine production by human peripheral blood mononuclear cells are independent of the prostaglandin subtype

inferredcites →https://doi.org/10.1046/j.1365-2567.2003.01749.xopenalex-snapshot

Dihomo‐γ‐linolenic acid inhibits tumour necrosis factor‐α production by human leucocytes independently of cyclooxygenase activity

inferredcites →https://doi.org/10.1054/plef.1999.0085openalex-snapshot

Essential fatty acids, lipid peroxidation and apoptosis

inferredcites →https://doi.org/10.1054/plef.1999.0125openalex-snapshot

Effect of polyunsaturated fatty acids on dexamethasone – induced gastric mucosal damage

inferredcites →https://doi.org/10.1074/jbc.c113.511261openalex-snapshot

Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins

inferredcites →https://doi.org/10.1074/jbc.m116.769422openalex-snapshot

Endogenous prostaglandin E2 amplifies IL-33 production by macrophages through an E prostanoid (EP)2/EP4-cAMP-EPAC-dependent pathway

inferredcites →https://doi.org/10.1074/jbc.ra118.005866openalex-snapshot

Prostaglandin E2 down-regulates sirtuin 1 (SIRT1), leading to elevated levels of aromatase, providing insights into the obesity–breast cancer connection

inferredcites →https://doi.org/10.1080/07388551.2016.1207153openalex-snapshot

Docosahexaenoic acid: one molecule diverse functions

inferredcites →https://doi.org/10.1084/jem.20142235openalex-snapshot

Biomechanical forces promote blood development through prostaglandin E2 and the cAMP–PKA signaling axis

inferredcites →https://doi.org/10.1093/eurheartj/eht467openalex-snapshot

The gut microbiome as novel cardio-metabolic target: the time has come!

inferredcites →https://doi.org/10.1093/genetics/163.2.581openalex-snapshot

Deficiencies in C20 Polyunsaturated Fatty Acids Cause Behavioral and Developmental Defects inCaenorhabditis elegans fat-3Mutants

inferredcites →https://doi.org/10.1093/gerona/glp101openalex-snapshot

Calorie Restriction Enhances T-Cell-Mediated Immune Response in Adult Overweight Men and Women

inferredcites →https://doi.org/10.1093/jn/138.10.1915openalex-snapshot

Long-Chain (n-3) Polyunsaturated Fatty Acids Prevent Metabolic and Vascular Disorders in Fructose-Fed Rats3

inferredcites →https://doi.org/10.1093/jn/nxy255openalex-snapshot

Increases in Colonic Bacterial Diversity after ω-3 Fatty Acid Supplementation Predict Decreased Colonic Prostaglandin E2 Concentrations in Healthy Adults

inferredcites →https://doi.org/10.1096/fj.00-0242fjeopenalex-snapshot

An intervention resembling caloric restriction prolongs life span and retards aging in yeast

inferredcites →https://doi.org/10.1096/fj.03-0837comopenalex-snapshot

A novel role for phospholipase A 2 isoforms in the checkpoint control of acute inflammation

inferredcites →https://doi.org/10.1096/fj.201500029ropenalex-snapshot

Lipoxin A 4 augments host defense in sepsis and reduces Pseudomonas aeruginosa virulence through quorum sensing inhibition

inferredcites →https://doi.org/10.1096/fj.201901163ropenalex-snapshot

Formyl peptide receptor 2 regulates monocyte recruitment to promote intestinal mucosal wound repair

inferredcites →https://doi.org/10.1097/00001756-199503270-00006openalex-snapshot

Inhibitors of PLA2 and NO synthase cooperate in producing amnesia of a spatial task

inferredcites →https://doi.org/10.1097/00004872-199715080-00010openalex-snapshot

Liver microsomal membrane fluidity and microsomal desaturase activities in adult spontaneously hypertensive rats

inferredcites →https://doi.org/10.1097/fjc.0000000000000768openalex-snapshot

Commentary on Zhao et al Manuscript Entitled: “Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies”

inferredcites →https://doi.org/10.1097/hjh.0000000000001378openalex-snapshot

Sodium butyrate suppresses angiotensin II-induced hypertension by inhibition of renal (pro)renin receptor and intrarenal renin–angiotensin system

inferredcites →https://doi.org/10.1097/shk.0b013e31822798c1openalex-snapshot

Lipoxin A4 Increases Survival by Decreasing Systemic Inflammation and Bacterial Load in Sepsis

inferredcites →https://doi.org/10.1101/gad.205294.112openalex-snapshot

ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy

inferredcites →https://doi.org/10.1111/acel.13150openalex-snapshot

Caenorhabditis elegans Lipin 1 moderates the lifespan‐shortening effects of dietary glucose by maintaining ω‐6 polyunsaturated fatty acids

inferredcites →https://doi.org/10.1111/j.1474-9726.2006.00237.xopenalex-snapshot

High oxidative damage levels in the longest‐living rodent, the naked mole‐rat

inferredcites →https://doi.org/10.1111/j.1474-9726.2009.00544.xopenalex-snapshot

SIRT6 protects against pathological damage caused by diet‐induced obesity

inferredcites →https://doi.org/10.1111/j.1753-4887.2007.tb00358.xopenalex-snapshot

Inflammaging as a Major Characteristic of Old People: Can It Be Prevented or Cured?

inferredcites →https://doi.org/10.1111/jgh.15006openalex-snapshot

Aging exacerbates high‐fat diet‐induced steatohepatitis through alteration in hepatic lipid metabolism in mice

inferredcites →https://doi.org/10.1126/sciadv.aar8320openalex-snapshot

PGE 2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo

inferredcites →https://doi.org/10.1126/science.aaa2340openalex-snapshot

Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

inferredcites →https://doi.org/10.1126/sciimmunol.aay9283openalex-snapshot

Organ-specific isoform selection of fatty acid–binding proteins in tissue-resident lymphocytes

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Pro- and anti-inflammatory roles of interleukin-1 in recurrence of bacterial cell wall-induced arthritis in rats

inferredcites →https://doi.org/10.1128/jcm.9.3.333-335.1979openalex-snapshot

Susceptibility of Staphylococcus aureus and group A, B, C, and G streptococci to free fatty acids

inferredcites →https://doi.org/10.1136/gutjnl-2017-314968openalex-snapshot

A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota

inferredcites →https://doi.org/10.1152/ajpheart.01053.2007openalex-snapshot

Age-related decrease in 15-lipoxygenase contributes to reduced vasorelaxation in rabbit aorta

inferredcites →https://doi.org/10.1152/ajpregu.00128.2013openalex-snapshot

Human inflammatory and resolving lipid mediator responses to resistance exercise and ibuprofen treatment

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Physical exercise increases urinary excretion of lipoxin A 4 and related compounds

inferredcites →https://doi.org/10.1155/2015/126408openalex-snapshot

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inferredcites →https://doi.org/10.1159/000364934openalex-snapshot

Low-Grade Systemic Inflammation Connects Aging, Metabolic Syndrome and Cardiovascular Disease

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Omega-6 Fatty Acids and Risk for Cardiovascular Disease

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Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage

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Lipoxin Generation is Related to Soluble Epoxide Hydrolase Activity in Severe Asthma

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Enhancement of bactericidal capacity of alveolar macrophages by human alveolar lining material.

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Supplementation of arachidonic acid-enriched oil increases arachidonic acid contents in plasma phospholipids, but does not increase their metabolites and clinical parameters in Japanese healthy elderly individuals: a randomized controlled study

inferredcites →https://doi.org/10.1186/1476-511x-13-30openalex-snapshot

Dietary supplementation of arachidonic acid increases arachidonic acid and lipoxin A4 contents in colon, but does not affect severity or prostaglandin E2 content in murine colitis model

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Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model

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Prostaglandin E2 secreted from feline adipose tissue-derived mesenchymal stem cells alleviate DSS-induced colitis by increasing regulatory T cells in mice

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PUFAs, BDNF and lipoxin A4 inhibit chemical-induced cytotoxicity of RIN5F cells in vitro and streptozotocin-induced type 2 diabetes mellitus in vivo

inferredcites →https://doi.org/10.1189/jlb.1112557openalex-snapshot

Sirtuin deacylases: a molecular link between metabolism and immunity

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Plasma lipid profiling in a large population-based cohort

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Omega 3 Improves Both apoB100-containing Lipoprotein Turnover and their Sphingolipid Profile in Hypertriglyceridemia

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Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

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Alzheimer disease in the United States (2010–2050) estimated using the 2010 census

inferredcites →https://doi.org/10.1242/jcs.00918openalex-snapshot

Long chain polyunsaturated fatty acids are required for efficient neurotransmission in C. elegans

inferredcites →https://doi.org/10.1254/jjp.83.277openalex-snapshot

Ca2+-Independent Phospholipase A2 Inhibiror Impairs Spatial Memory of Mice.

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Mesenchymal Stem Cells Reverse Diabetic Nephropathy Disease via Lipoxin A4 by Targeting Transforming Growth Factor β (TGF-β)/smad Pathway and Pro-Inflammatory Cytokines

inferredcites →https://doi.org/10.1301/nr.2007.dec.s173-s176openalex-snapshot

Inflammaging as a Major Characteristic of Old People: Can It Be Prevented or Cured?

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Fetal Alcohol Syndrome and Essential Fatty Acids

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PGH1, the Precursor for the Anti-Inflammatory Prostaglandins of the 1-series, Is a Potent Activator of the Pro-Inflammatory Receptor CRTH2/DP2

showing the first 200 of 233 · page through all 233

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Anti‐ageing activities of nanovesicles derived from Artemisia princeps in human dermal cells and human skin model

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The Association Between Dietary Magnesium Intake and Pulmonary Function: Recent Fndings from NHANES 2007–2012

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Profiling the oxylipidome in aged mice after chronic ethanol feeding: Identifying lipid metabolites as drivers of hepatocyte stress

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Up-regulation of myelin-associated glycoprotein is associated with the ameliorating effect of omega-3 polyunsaturated fatty acids on Alzheimer's disease progression in APP–PS1 transgenic mice

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AFM-based nanomechanical evaluation of human umbilical cord mesenchymal stem cells for alcohol-associated liver injury

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Molecular biochemical aspects of salt (sodium chloride) in inflammation and immune response with reference to hypertension and type 2 diabetes mellitus

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Syntaxin interacts with arachidonic acid to prevent diabetes mellitus

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Fecal Dysosmobacter spp. concentration is linked to plasma lipidome in insulin-resistant individuals with overweight, obesity and metabolic syndrome

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Senescent fibroblasts drive CD8+ T cell dysfunction in colorectal cancer via CD36-mediated lipid transfer and peroxidation

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Role for BLT1 in regulating inflammation within adipose tissue immune cells of aged mice

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Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

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Impact of Aging on Sperm Quality of Sentul Roosters

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Potential prognostic markers of cellular senescence in age-associated cardiovascular pathology

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The SIRT1/STAT3 axis as a central regulator of immune, inflammatory, and lipid metabolic dysregulation in rheumatoid arthritis: therapeutic implications

inferred← citeshttps://doi.org/10.3389/fmed.2024.1484345openalex-snapshot

Skin senescence—from basic research to clinical practice

inferred← citeshttps://doi.org/10.3389/fnut.2022.890277openalex-snapshot

Beneficial Actions of Essential Fatty Acids in Streptozotocin-Induced Type 1 Diabetes Mellitus

inferred← citeshttps://doi.org/10.3389/fnut.2025.1580037openalex-snapshot

Lower phase angle as a marker for poor prognosis in patients with chronic kidney disease: a cohort study

inferred← citeshttps://doi.org/10.3389/fonc.2021.757073openalex-snapshot

Lipoxins and Resolvins in Patients With Pancreatic Cancer: A Preliminary Report

inferred← citeshttps://doi.org/10.3389/fphar.2022.1056078openalex-snapshot

Yangyinqingfei decoction attenuates PM2.5-induced lung injury by enhancing arachidonic acid metabolism

inferred← citeshttps://doi.org/10.3389/fpsyt.2023.1234461openalex-snapshot

Assessing the risk of prenatal depressive symptoms in Chinese women: an integrated evaluation of serum metabolome, multivitamin supplement intake, and clinical blood indicators

inferred← citeshttps://doi.org/10.3389/fragi.2021.773795openalex-snapshot

Recent Advances in Studying Age-Associated Lipids Alterations and Dietary Interventions in Mammals

inferred← citeshttps://doi.org/10.3389/fragi.2026.1735269openalex-snapshot

Epigenetic program of ontogenesis and hyperfunction theory: reinterpreting the mechanisms of aging

inferred← citeshttps://doi.org/10.3390/antiox15040439openalex-snapshot

Life-Course Regulation of Health and Disease by Nitric Oxide: Mechanistic Insights

inferred← citeshttps://doi.org/10.3390/app14083192openalex-snapshot

Comparative Analysis of Fatty Acids Concentration in Liver and Muscle Tissues of Rats and Mice

inferred← citeshttps://doi.org/10.3390/biom11121873openalex-snapshot

Essential Fatty Acids and Their Metabolites in the Pathobiology of Inflammation and Its Resolution

inferred← citeshttps://doi.org/10.3390/biom12060797openalex-snapshot

Gamma-Linolenic Acid (GLA) Protects against Ionizing Radiation-Induced Damage: An In Vitro and In Vivo Study

inferred← citeshttps://doi.org/10.3390/biom13091332openalex-snapshot

Infection, Inflammation, and Immunity in Sepsis

inferred← citeshttps://doi.org/10.3390/cells11111772openalex-snapshot

Peroxiredoxin, Senescence, and Cancer

inferred← citeshttps://doi.org/10.3390/cells11182831openalex-snapshot

Human Amniotic Membrane Mesenchymal Stem Cell-Synthesized PGE2 Exerts an Immunomodulatory Effect on Neutrophil Extracellular Trap in a PAD-4-Dependent Pathway through EP2 and EP4

inferred← citeshttps://doi.org/10.3390/cells12060860openalex-snapshot

Cellular Senescence, a Novel Area of Investigation for Metastatic Diseases

inferred← citeshttps://doi.org/10.3390/ijms222312803openalex-snapshot

Anti-Inflammatory Function of Fatty Acids and Involvement of Their Metabolites in the Resolution of Inflammation in Chronic Obstructive Pulmonary Disease

inferred← citeshttps://doi.org/10.3390/ijms23031308openalex-snapshot

Involvement of Fatty Acids and Their Metabolites in the Development of Inflammation in Atherosclerosis

inferred← citeshttps://doi.org/10.3390/ijms232314717openalex-snapshot

Integrated Transcriptome and Metabolome Analysis Reveals the Regulatory Mechanisms of FASN in Geese Granulosa Cells

inferred← citeshttps://doi.org/10.3390/ijms24032116openalex-snapshot

Dihomo-γ-Linolenic Acid (20:3n-6)—Metabolism, Derivatives, and Potential Significance in Chronic Inflammation

inferred← citeshttps://doi.org/10.3390/ijms24119340openalex-snapshot

Targeting the Inflammatory Hallmarks of Obesity-Associated Osteoarthritis: Towards Nutraceutical-Oriented Preventive and Complementary Therapeutic Strategies Based on n-3 Polyunsaturated Fatty Acids

inferred← citeshttps://doi.org/10.3390/ijms241310717openalex-snapshot

DHA/EPA (Omega-3) and LA/GLA (Omega-6) as Bioactive Molecules in Neurodegenerative Diseases

inferred← citeshttps://doi.org/10.3390/ijms25126749openalex-snapshot

Effects of Sapindus mukorossi Seed Oil on Bone Healing Efficiency: An Animal Study

inferred← citeshttps://doi.org/10.3390/jcm12185995openalex-snapshot

Impact of Selected Eicosanoids in Normal and Pathological Pregnancies

inferred← citeshttps://doi.org/10.3390/membranes11120919openalex-snapshot

Lipids in Pathophysiology and Development of the Membrane Lipid Therapy: New Bioactive Lipids

inferred← citeshttps://doi.org/10.3390/metabo14010019openalex-snapshot

Impact of Reperfusion on Plasma Oxylipins in ST-Segment Elevation Myocardial Infarction

inferred← citeshttps://doi.org/10.3390/molecules27248950openalex-snapshot

Indolylazine Derivative Induces Chaperone Expression in Aged Neural Cells and Prevents the Progression of Alzheimer’s Disease

inferred← citeshttps://doi.org/10.3390/nu14040749openalex-snapshot

Arachidonic Acid as Mechanotransducer of Renin Cell Baroreceptor

inferred← citeshttps://doi.org/10.3390/nu14163273openalex-snapshot

Relevance of ω-6 GLA Added to ω-3 PUFAs Supplements for ADHD: A Narrative Review

inferred← citeshttps://doi.org/10.3390/nu15163578openalex-snapshot

Natural Phytochemicals as SIRT Activators—Focus on Potential Biochemical Mechanisms

inferred← citeshttps://doi.org/10.3390/nu15234992openalex-snapshot

Protective Effect of Alpha-Linolenic Acid on Human Oral Squamous Cell Carcinoma Metastasis and Apoptotic Cell Death

inferred← citeshttps://doi.org/10.3390/pharmaceutics16070913openalex-snapshot

Harnessing Potential of ω-3 Polyunsaturated Fatty Acid with Nanotechnology for Enhanced Breast Cancer Therapy: A Comprehensive Investigation into ALA-Based Liposomal PTX Delivery

inferred← citeshttps://doi.org/10.34172/jhp.53271openalex-snapshot

Bioactive components, mechanisms, and applications of functional seeds (Flaxseed, chia, pumpkin, hemp, and sesame) in insulin resistance: A mini-review

inferred← citeshttps://doi.org/10.36660/abc.20260795openalex-snapshot

Diretriz Brasileira de Cardiogeriatria – 2026

inferred← citeshttps://doi.org/10.5219/1931openalex-snapshot

Determination of the fatty and amino acid composition of camel milk, milk powder and shubat

inferred← citeshttps://doi.org/10.53941/hm.2025.100017openalex-snapshot

Physiological and Pathological Insights into the Circadian Rhythm of Polyunsaturated Fatty Acids Metabolism

inferred← citeshttps://doi.org/10.56936/18290825-2026.20v.1-4openalex-snapshot

How Effective Is Our “Universal” Receptor System?

inferred← citeshttps://doi.org/10.6084/m9.figshare.23614141openalex-snapshot

Additional file 1 of Identification of cuproptosis-related molecular subtypes as a biomarker for differentiating active from latent tuberculosis in children

inferred← citeshttps://doi.org/10.6084/m9.figshare.23614144openalex-snapshot

Additional file 2 of Identification of cuproptosis-related molecular subtypes as a biomarker for differentiating active from latent tuberculosis in children

inferred← citeshttps://doi.org/10.6084/m9.figshare.23614150openalex-snapshot

Additional file 3 of Identification of cuproptosis-related molecular subtypes as a biomarker for differentiating active from latent tuberculosis in children

inferred← citeshttps://doi.org/10.6084/m9.figshare.23614153openalex-snapshot

Additional file 4 of Identification of cuproptosis-related molecular subtypes as a biomarker for differentiating active from latent tuberculosis in children

inferred← citeshttps://doi.org/10.6084/m9.figshare.26157134openalex-snapshot

Additional file 1 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26157349openalex-snapshot

Additional file 2 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26741666openalex-snapshot

Additional file 3 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26741669openalex-snapshot

Additional file 4 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26741672openalex-snapshot

Additional file 5 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26741675openalex-snapshot

Additional file 6 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26741678openalex-snapshot

Additional file 7 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26741681openalex-snapshot

Additional file 8 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26741684openalex-snapshot

Additional file 9 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26741687openalex-snapshot

Additional file 10 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26741690openalex-snapshot

Additional file 11 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26741693openalex-snapshot

Additional file 12 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26741696openalex-snapshot

Additional file 13 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.6084/m9.figshare.26741699openalex-snapshot

Additional file 14 of Autophagy modulation effect on homotypic transfer of intracellular components via tunneling nanotubes in mesenchymal stem cells

inferred← citeshttps://doi.org/10.61634/2782-3024-2024-13-3-16openalex-snapshot

Features of the impact of production factors on the processes of premature aging and changes in biological age

inferred← citeshttps://doi.org/10.62425/rtpharma.1589019openalex-snapshot

Intervertebral disc degeneration, inflammation, and bioactive lipids

inferred← citeshttps://doi.org/10.64898/2026.09.18.752516openalex-snapshot

Multiomics Characterization Identifies S1P-secreting USS High Skeletal Muscle Stem Cells as Essential Drivers of Niche Remodeling and Muscle Regeneration

inferred← citeshttps://doi.org/10.7150/ijms.98778openalex-snapshot

The Biomarkers in Extreme Longevity: Insights Gained from Metabolomics and Proteomics

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