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The Future Challenge of Reactive Oxygen Species (ROS) in Hypertension: From Bench to Bed Side

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Vitamins E and C in the Prevention of Cardiovascular Disease in Men
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The Nox1/4 Dual Inhibitor GKT137831 or Nox4 Knockdown Inhibits Angiotensin‐II‐Induced Adult Mouse Cardiac Fibroblast Proliferation and Migration. AT1 Physically Associates With Nox4
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Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease
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Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus
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Reactive oxygen species in vascular biology: implications in hypertension
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Role of neuronal nitric oxide synthase in the regulation of the neuroendocrine stress response in rodents: insights from mutant mice
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Polyamine synthesis inhibition induces S phase cell cycle arrest in vascular smooth muscle cells
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Salt-sensitive hypertension in mitochondrial superoxide dismutase deficiency is associated with intra-renal oxidative stress and inflammation
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Allopurinol, uric acid, and oxidative stress in cardiorenal disease
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Oxidative stress in diabetic nephropathy: Basic and clinical information
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Oxidative Stress and Hypertension: Current Concepts
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The Nox Family of NADPH Oxidases: Friend or Foe of the Vascular System?
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Subunit structure of bovine milk xanthine oxidase. Effect of limited cleavage by proteolytic enzymes on activity and structure
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Serotonin in peripheral blood reflects oxidative stress and plays a crucial role in atherosclerosis: Novel insights toward holistic anti-atherothrombotic strategy
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In vitro measurements and interpretation of total antioxidant capacity
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Vascular NADPH oxidases: molecular mechanisms of activation
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Free radicals, reactive oxygen species, oxidative stress and its classification
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Oxyl radicals, redox-sensitive signalling cascades and antioxidants
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Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
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Evaluation of antioxidants: Scope, limitations and relevance of assays
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Molecular Mechanisms of Hypertension—Reactive Oxygen Species and Antioxidants: A Basic Science Update for the Clinician
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Mitochondria: More Than Just a Powerhouse
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Reduction in extracellular superoxide dismutase activity in African-American patients with hypertension
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The chemical biology of nitric oxide: Implications in cellular signaling
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Reversal of Endothelial Nitric Oxide Synthase Uncoupling and Up-Regulation of Endothelial Nitric Oxide Synthase Expression Lowers Blood Pressure in Hypertensive Rats
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Adaptation and remodeling of vascular wall; biomechanical response to hypertension
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Mitochondria in health and disease: perspectives on a new mitochondrial biology
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Pathophysiological relevance of NO signaling in the cardiovascular system: Novel insight from mice lacking all NO synthases
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European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
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Identification of uric acid and xanthine oxidase in atherosclerotic plaque11This study was supported by a grant from the Committee on Research Allocation, Department of Surgery, State University of New York Health Science Center at Brooklyn, Brooklyn, New York.
inferredcites →https://doi.org/10.1016/s0002-9440(10)63290-7openalex-snapshot
Chronic High Pressure-Induced Arterial Oxidative Stress
inferredcites →https://doi.org/10.1016/s0008-6363(99)00094-2openalex-snapshot
Signal transduction of eNOS activation
inferredcites →https://doi.org/10.1016/s0140-6736(03)13637-9openalex-snapshot
Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials
inferredcites →https://doi.org/10.1016/s0140-6736(14)60648-6openalex-snapshot
Prevention of chronic disease in the 21st century: elimination of the leading preventable causes of premature death and disability in the USA
inferredcites →https://doi.org/10.1016/s0891-5849(00)00236-7openalex-snapshot
Molecular action of vitamin E in lipoprotein oxidation:
inferredcites →https://doi.org/10.1016/s0891-5849(02)00956-5openalex-snapshot
Structure and function of xanthine oxidoreductase: where are we now?
inferredcites →https://doi.org/10.1016/s0895-7061(01)02317-2openalex-snapshot
Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals
inferredcites →https://doi.org/10.1021/cb100219nopenalex-snapshot
A Novel and Specific NADPH Oxidase-1 (Nox1) Small-Molecule Inhibitor Blocks the Formation of Functional Invadopodia in Human Colon Cancer Cells
inferredcites →https://doi.org/10.1038/ajh.2010.173openalex-snapshot
High Salt Intake Delayed Angiotensin II-Induced Hypertension in Mice With a Genetic Variant of NADPH Oxidase
inferredcites →https://doi.org/10.1038/ncpneph0283openalex-snapshot
Mechanisms of Disease: oxidative stress and inflammation in the pathogenesis of hypertension
inferredcites →https://doi.org/10.1038/nrd3403openalex-snapshot
Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets
inferredcites →https://doi.org/10.1038/nri1312openalex-snapshot
NOX enzymes and the biology of reactive oxygen
inferredcites →https://doi.org/10.1038/nrm2256openalex-snapshot
ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
inferredcites →https://doi.org/10.1038/sj.bjp.0705557openalex-snapshot
Role of oxidative stress and nitric oxide in regulation of spontaneous tone in aorta of DOCA‐salt hypertensive rats
inferredcites →https://doi.org/10.1038/sj.jhh.1001945openalex-snapshot
Byproducts of oxidative protein damage and antioxidant enzyme activities in plasma of patients with different degrees of essential hypertension
inferredcites →https://doi.org/10.1042/0264-6021:3570593openalex-snapshot
Nitric oxide synthases: structure, function and inhibition
inferredcites →https://doi.org/10.1042/cs20050307openalex-snapshot
Endothelin-1-induced oxidative stress in DOCA-salt hypertension involves NADPH-oxidase-independent mechanisms
inferredcites →https://doi.org/10.1042/cs20070343openalex-snapshot
Decrease in oxidative stress through supplementation of vitamins C and E is associated with a reduction in blood pressure in patients with essential hypertension
inferredcites →https://doi.org/10.1042/cs20080057openalex-snapshot
The angiotensin-converting enzyme insertion/deletion polymorphism is associated with phagocytic NADPH oxidase-dependent superoxide generation: potential implication in hypertension
inferredcites →https://doi.org/10.1042/cs20120651openalex-snapshot
New roles for old pathways? A circuitous relationship between reactive oxygen species and cyclo-oxygenase in hypertension
inferredcites →https://doi.org/10.1042/cs20160812openalex-snapshot
Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation
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Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: Evidence for an involvement of protein kinase C
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Role of macula densa nitric oxide and cGMP in the regulation of tubuloglomerular feedback
inferredcites →https://doi.org/10.1056/nejm198501173120305openalex-snapshot
Oxygen-Derived Free Radicals in Postischemic Tissue Injury
inferredcites →https://doi.org/10.1056/nejmoa013591openalex-snapshot
Endothelial Function and Oxidative Stress in Renovascular Hypertension
inferredcites →https://doi.org/10.1073/pnas.88.22.10045openalex-snapshot
Does superoxide underlie the pathogenesis of hypertension?
inferredcites →https://doi.org/10.1073/pnas.93.16.8745openalex-snapshot
Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits.
inferredcites →https://doi.org/10.1073/pnas.95.8.4754openalex-snapshot
Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats
inferredcites →https://doi.org/10.1073/pnas.98.2.735openalex-snapshot
Myoglobin: A scavenger of bioactive NO
inferredcites →https://doi.org/10.1074/jbc.m113.521344openalex-snapshot
Selective Recapitulation of Conserved and Nonconserved Regions of Putative NOXA1 Protein Activation Domain Confers Isoform-specific Inhibition of Nox1 Oxidase and Attenuation of Endothelial Cell Migration
inferredcites →https://doi.org/10.1074/jbc.m302573200openalex-snapshot
Myoglobin Protects the Heart from Inducible Nitric-oxide Synthase (iNOS)-mediated Nitrosative Stress
inferredcites →https://doi.org/10.1074/jbc.m404044200openalex-snapshot
Three Different Oxygen-induced Radical Species in Endothelial Nitric-oxide Synthase Oxygenase Domain under Regulation by L-Arginine and Tetrahydrobiopterin
inferredcites →https://doi.org/10.1074/jbc.m703132200openalex-snapshot
Oxidative Stress-mediated Mesangial Cell Proliferation Requires RAC-1/Reactive Oxygen Species Production and β4 Integrin Expression
inferredcites →https://doi.org/10.1080/15216540252774720openalex-snapshot
Redox Regulation in Mammalian Signal Transduction
inferredcites →https://doi.org/10.1081/ceh-100100063openalex-snapshot
INCREASED ARGINASE ACTIVITY IN AORTA OF MINERALOCORTICOID-SALT HYPERTENSIVE RATS
inferredcites →https://doi.org/10.1089/ars.2008.2027openalex-snapshot
Redox Control of Endothelial Function and Dysfunction: Molecular Mechanisms and Therapeutic Opportunities
inferredcites →https://doi.org/10.1089/ars.2009.2584openalex-snapshot
NADPH Oxidase 1 Deficiency Alters Caveolin Phosphorylation and Angiotensin II–Receptor Localization in Vascular Smooth Muscle
inferredcites →https://doi.org/10.1089/ars.2009.2585openalex-snapshot
Small-Molecule NOX Inhibitors: ROS-Generating NADPH Oxidases as Therapeutic Targets
inferredcites →https://doi.org/10.1089/ars.2010.3874openalex-snapshot
Oxidative Stress-Dependent Cyclooxygenase-2-Derived Prostaglandin F 2α Impairs Endothelial Function in Renovascular Hypertensive Rats
inferredcites →https://doi.org/10.1089/ars.2011.4335openalex-snapshot
Reciprocal Relationship Between Reactive Oxygen Species and Cyclooxygenase-2 and Vascular Dysfunction in Hypertension
inferredcites →https://doi.org/10.1089/ars.2012.4641openalex-snapshot
Angiotensin II, NADPH Oxidase, and Redox Signaling in the Vasculature
inferredcites →https://doi.org/10.1089/ars.2013.5259openalex-snapshot
Oxidative Stress in Hypertension: Role of the Kidney
inferredcites →https://doi.org/10.1089/ars.2013.5814openalex-snapshot
Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement
inferredcites →https://doi.org/10.1093/eurheartj/ehr304openalex-snapshot
Nitric oxide synthases: regulation and function
inferredcites →https://doi.org/10.1096/fj.99-0960comopenalex-snapshot
Physiological cyclic stretch directs L‐arginine transport and metabolism to collagen synthesis in vascular smooth muscle
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Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetic risk of hypertension
inferredcites →https://doi.org/10.1097/00004872-200206000-00036openalex-snapshot
Increasing plasma fatty acids elevates F2-isoprostanes in humans: implications for the cardiovascular risk factor cluster
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Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells
inferredcites →https://doi.org/10.1097/00005344-200111002-00004openalex-snapshot
Endothelial Dysfunction in Hypertension
inferredcites →https://doi.org/10.1097/01.hjh.0000125441.28861.9fopenalex-snapshot
Renal xanthine oxidoreductase activity during development of hypertension in spontaneously hypertensive rats
inferredcites →https://doi.org/10.1097/01.hjh.0000166837.78559.93openalex-snapshot
Arginase inhibition reduces endothelial dysfunction and blood pressure rising in spontaneously hypertensive rats
inferredcites →https://doi.org/10.1097/01.hjh.0000187259.94448.8aopenalex-snapshot
Effect of supplementation with antioxidants upon long-term risk of hypertension in the SU.VI.MAX study: association with plasma antioxidant levels
inferredcites →https://doi.org/10.1097/fjc.0000000000000082openalex-snapshot
Inhibition of NOX/VPO1 Pathway and Inflammatory Reaction by Trimethoxystilbene in Prevention of Cardiovascular Remodeling in Hypoxia-induced Pulmonary Hypertensive Rats
inferredcites →https://doi.org/10.1097/fjc.0b013e31827fe46eopenalex-snapshot
Endothelial Dysfunction in Diabetes and Hypertension
inferredcites →https://doi.org/10.1097/hjh.0b013e3281fc975aopenalex-snapshot
2007 Guidelines for the Management of Arterial Hypertension
inferredcites →https://doi.org/10.1111/bph.13828openalex-snapshot
Reactive oxygen species: key regulators in vascular health and diseases
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Comparative pharmacology of chemically distinct NADPH oxidase inhibitors
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Increased intracellular pH at the macula densa activates nNOS during tubuloglomerular feedback
inferredcites →https://doi.org/10.1111/j.1755-5922.2011.00310.xopenalex-snapshot
Opportunity Nox: The Future of NADPH Oxidases as Therapeutic Targets in Cardiovascular Disease
inferredcites →https://doi.org/10.1113/jphysiol.2003.055913openalex-snapshot
Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications
inferredcites →https://doi.org/10.1152/ajpcell.00283.2008openalex-snapshot
Radical-free biology of oxidative stress
inferredcites →https://doi.org/10.1152/ajpendo.2001.280.1.e75openalex-snapshot
Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells
inferredcites →https://doi.org/10.1152/ajpendo.91023.2008openalex-snapshot
Involvement of NADPH oxidase in oxidized LDL-induced upregulation of heat shock factor-1 and plasminogen activator inhibitor-1 in vascular endothelial cells
inferredcites →https://doi.org/10.1152/ajpheart.00089.2013openalex-snapshot
Role of mitochondrial oxidative stress in hypertension
inferredcites →https://doi.org/10.1152/ajpregu.00250.2005openalex-snapshot
Oxidative stress and nitric oxide deficiency in the kidney: a critical link to hypertension?
inferredcites →https://doi.org/10.1152/ajpregu.00758.2002openalex-snapshot
Vascular NAD(P)H oxidases: specific features, expression, and regulation
inferredcites →https://doi.org/10.1152/ajpregu.00758.2004openalex-snapshot
Arginase inhibition restores arteriolar endothelial function in Dahl rats with salt-induced hypertension
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Nitric oxide synthase in the JGA of the SHR: expression and role in tubuloglomerular feedback
inferredcites →https://doi.org/10.1152/physrev.00018.2001openalex-snapshot
Free Radicals in the Physiological Control of Cell Function
inferredcites →https://doi.org/10.1152/physrev.00029.2006openalex-snapshot
Nitric Oxide and Peroxynitrite in Health and Disease
inferredcites →https://doi.org/10.1152/physrev.00042.2007openalex-snapshot
eNOS Activation by Physical Forces: From Short-Term Regulation of Contraction to Chronic Remodeling of Cardiovascular Tissues
inferredcites →https://doi.org/10.1155/2016/9124676openalex-snapshot
Serum Superoxide Dismutase Is Associated with Vascular Structure and Function in Hypertensive and Diabetic Patients
inferredcites →https://doi.org/10.1159/000479441openalex-snapshot
Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy
inferredcites →https://doi.org/10.1161/01.atv.0000196651.64776.51openalex-snapshot
Coronary Artery Superoxide Production and Nox Isoform Expression in Human Coronary Artery Disease
inferredcites →https://doi.org/10.1161/01.atv.0000258415.32883.bfopenalex-snapshot
Angiotensin II Induces Endothelial Xanthine Oxidase Activation
inferredcites →https://doi.org/10.1161/01.cir.0000039528.49161.e9openalex-snapshot
Increased Oxidative Stress and Platelet Activation in Patients With Hypertension and Renovascular Disease
inferredcites →https://doi.org/10.1161/01.cir.0000124223.00113.a4openalex-snapshot
gp91phox-Containing NADPH Oxidase Mediates Endothelial Dysfunction in Renovascular Hypertension
inferredcites →https://doi.org/10.1161/01.cir.95.3.588openalex-snapshot
Role of Superoxide in Angiotensin II–Induced but Not Catecholamine-Induced Hypertension
inferredcites →https://doi.org/10.1161/01.hyp.0000032100.23772.98openalex-snapshot
Role of p47 phox in Vascular Oxidative Stress and Hypertension Caused by Angiotensin II
inferredcites →https://doi.org/10.1161/01.hyp.0000039961.13718.00openalex-snapshot
Ascorbic Acid Reduces Blood Pressure and Arterial Stiffness in Type 2 Diabetes
inferredcites →https://doi.org/10.1161/01.hyp.0000068370.21009.38openalex-snapshot
Antioxidant Activities and Oxidative Stress Byproducts in Human Hypertension
inferredcites →https://doi.org/10.1161/01.hyp.0000100443.09293.4fopenalex-snapshot
Reactive Oxygen Species in the Vasculature
inferredcites →https://doi.org/10.1161/01.hyp.0000146907.82869.f2openalex-snapshot
Upregulation of Vascular Arginase in Hypertension Decreases Nitric Oxide–Mediated Dilation of Coronary Arterioles
inferredcites →https://doi.org/10.1161/01.hyp.21.6.929openalex-snapshot
Vasodilation to acetylcholine in primary and secondary forms of human hypertension.
inferredcites →https://doi.org/10.1161/01.hyp.33.6.1353openalex-snapshot
Superoxide Anion Production Is Increased in a Model of Genetic Hypertension
inferredcites →https://doi.org/10.1161/01.hyp.36.5.878openalex-snapshot
Plasma Hydrogen Peroxide Production in Human Essential Hypertension
inferredcites →https://doi.org/10.1161/01.hyp.37.2.505openalex-snapshot
Role of Endothelin and Isoprostanes in Slow Pressor Responses to Angiotensin II
inferredcites →https://doi.org/10.1161/01.res.0000017632.83720.68openalex-snapshot
Disruption of Inducible Nitric Oxide Synthase Improves β-Adrenergic Inotropic Responsiveness but Not the Survival of Mice With Cytokine-Induced Cardiomyopathy
inferredcites →https://doi.org/10.1161/01.res.0000091261.19387.aeopenalex-snapshot
Mitochondrial Sources of H 2 O 2 Generation Play a Key Role in Flow-Mediated Dilation in Human Coronary Resistance Arteries
inferredcites →https://doi.org/10.1161/01.res.0000263381.83835.7bopenalex-snapshot
Endothelial Nox2 Overexpression Potentiates Vascular Oxidative Stress and Hemodynamic Response to Angiotensin II
inferredcites →https://doi.org/10.1161/01.res.80.1.45openalex-snapshot
p22phox mRNA Expression and NADPH Oxidase Activity Are Increased in Aortas From Hypertensive Rats
inferredcites →https://doi.org/10.1161/01.res.85.9.829openalex-snapshot
Cytokine-Mediated Apoptosis in Cardiac Myocytes
inferredcites →https://doi.org/10.1161/01.res.86.2.e36openalex-snapshot
Tetrahydrobiopterin Improves Endothelium-Dependent Vasodilation in Chronic Smokers
inferredcites →https://doi.org/10.1161/01.res.87.10.840openalex-snapshot
Endothelial Dysfunction in Cardiovascular Diseases: The Role of Oxidant Stress
inferredcites →https://doi.org/10.1161/01.res.88.2.e14openalex-snapshot
Mechanisms Underlying Endothelial Dysfunction in Diabetes Mellitus
inferredcites →https://doi.org/10.1161/atvbaha.108.181610openalex-snapshot
NADPH Oxidases: Functions and Pathologies in the Vasculature
inferredcites →https://doi.org/10.1161/circresaha.107.148015openalex-snapshot
Hypoxia-Dependent Regulation of Nonphagocytic NADPH Oxidase Subunit NOX4 in the Pulmonary Vasculature
inferredcites →https://doi.org/10.1161/circresaha.107.162800openalex-snapshot
Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction
inferredcites →https://doi.org/10.1161/circresaha.108.188771openalex-snapshot
Age-Accelerated Atherosclerosis Correlates With Failure to Upregulate Antioxidant Genes
inferredcites →https://doi.org/10.1161/circresaha.109.214601openalex-snapshot
Therapeutic Targeting of Mitochondrial Superoxide in Hypertension
inferredcites →https://doi.org/10.1161/circulationaha.105.538934openalex-snapshot
Nox1 Overexpression Potentiates Angiotensin II-Induced Hypertension and Vascular Smooth Muscle Hypertrophy in Transgenic Mice
inferredcites →https://doi.org/10.1161/circulationaha.105.573709openalex-snapshot
Nox1 Is Involved in Angiotensin II–Mediated Hypertension
inferredcites →https://doi.org/10.1161/circulationaha.110.992362openalex-snapshot
Hypertension
inferredcites →https://doi.org/10.1161/circulationaha.112.132159openalex-snapshot
NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis
inferredcites →https://doi.org/10.1161/hh0102.102757openalex-snapshot
Cardiac-Specific Overexpression of Inducible Nitric Oxide Synthase Does Not Result in Severe Cardiac Dysfunction
inferredcites →https://doi.org/10.1161/hh1701.096037openalex-snapshot
Novel Competitive Inhibitor of NAD(P)H Oxidase Assembly Attenuates Vascular O2−and Systolic Blood Pressure in Mice
inferredcites →https://doi.org/10.1161/hy1101.093423openalex-snapshot
NADH/NADPH Oxidase and Enhanced Superoxide Production in the Mineralocorticoid Hypertensive Rat
inferredcites →https://doi.org/10.1161/hypertensionaha.108.127928openalex-snapshot
Attenuation of Angiotensin II–Induced Vascular Dysfunction and Hypertension by Overexpression of Thioredoxin 2
inferredcites →https://doi.org/10.1161/hypertensionaha.111.184291openalex-snapshot
p47 phox Is Required for Afferent Arteriolar Contractile Responses to Angiotensin II and Perfusion Pressure in Mice
inferredcites →https://doi.org/10.1161/hypertensionaha.113.01291openalex-snapshot
Renal Collecting Duct NOS1 Maintains Fluid–Electrolyte Homeostasis and Blood Pressure
inferredcites →https://doi.org/10.1161/hypertensionaha.114.03261openalex-snapshot
Increased Reactive Oxygen Species, Metabolic Maladaptation, and Autophagy Contribute to Pulmonary Arterial Hypertension–Induced Ventricular Hypertrophy and Diastolic Heart Failure
inferredcites →https://doi.org/10.1161/hypertensionaha.114.03953openalex-snapshot
Allopurinol Initiation and Change in Blood Pressure in Older Adults With Hypertension
inferredcites →https://doi.org/10.1161/hypertensionaha.114.04468openalex-snapshot
Null Mutation of the Nicotinamide Adenine Dinucleotide Phosphate–Oxidase Subunit p67 phox Protects the Dahl-S Rat From Salt-Induced Reductions in Medullary Blood Flow and Glomerular Filtration Rate
inferredcites →https://doi.org/10.1161/hypertensionaha.115.06280openalex-snapshot
Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats
inferredcites →https://doi.org/10.1161/hypertensionaha.115.06344openalex-snapshot
Allopurinol and Cardiovascular Outcomes in Adults With Hypertension
inferredcites →https://doi.org/10.1161/hypertensionaha.115.07032openalex-snapshot
Inhibition of Nitric Oxide Synthase 1 Induces Salt-Sensitive Hypertension in Nitric Oxide Synthase 1α Knockout and Wild-Type Mice
inferredcites →https://doi.org/10.1161/hypertensionaha.115.07085openalex-snapshot
Mitochondrial Cyclophilin D in Vascular Oxidative Stress and Hypertension
inferredcites →https://doi.org/10.1161/jaha.113.000376openalex-snapshot
Unacylated Ghrelin Promotes Skeletal Muscle Regeneration Following Hindlimb Ischemia via SOD‐2–Mediated miR‐221/222 Expression
inferredcites →https://doi.org/10.1172/jci0213265openalex-snapshot
Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death
inferredcites →https://doi.org/10.1172/jci10506openalex-snapshot
Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice
inferredcites →https://doi.org/10.1172/jci115035openalex-snapshot
Preservation of the endogenous antioxidants in low density lipoprotein by ascorbate but not probucol during oxidative modification.
inferredcites →https://doi.org/10.1172/jci116491openalex-snapshot
Hypercholesterolemia increases endothelial superoxide anion production.
inferredcites →https://doi.org/10.1172/jci118623openalex-snapshot
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.
inferredcites →https://doi.org/10.1172/jci119131openalex-snapshot
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
inferredcites →https://doi.org/10.1172/jci119782openalex-snapshot
Inducible nitric oxide synthase: what difference does it make?
inferredcites →https://doi.org/10.1172/jci13265openalex-snapshot
Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death
inferredcites →https://doi.org/10.1253/circj.cj-11-0388openalex-snapshot
Pathophysiological Roles of NADPH Oxidase/Nox Family Proteins in the Vascular System - Review and Perspective -
inferredcites →https://doi.org/10.1517/13543776.2011.584870openalex-snapshot
NADPH oxidase inhibitors: a patent review
inferredcites →https://doi.org/10.1681/asn.2015050515openalex-snapshot
Macula Densa Nitric Oxide Synthase 1β Protects against Salt-Sensitive Hypertension
inferredcites →https://doi.org/10.2174/0929867043365369openalex-snapshot
Oxidative Stress, Antioxidants, and Endothelial Function
inferredcites →https://doi.org/10.2174/1389201011208062456openalex-snapshot
Novel Therapeutic Approaches in Limiting Oxidative Stress and Inflammation
inferredcites →https://doi.org/10.2174/138920112804583087openalex-snapshot
Pattern Recognition Receptors and Control of Innate Immunity: Role of Nucleic Acids
inferredcites →https://doi.org/10.2337/db09-0858openalex-snapshot
Unacylated Ghrelin Rescues Endothelial Progenitor Cell Function in Individuals With Type 2 Diabetes
inferredcites →https://doi.org/10.2337/db14-0991openalex-snapshot
Unacylated Ghrelin Induces Oxidative Stress Resistance in a Glucose Intolerance and Peripheral Artery Disease Mouse Model by Restoring Endothelial Cell miR-126 Expression
inferredcites →https://doi.org/10.3109/07853890.2011.653393openalex-snapshot
Oxidative stress, Noxs, and hypertension: Experimental evidence and clinical controversies
inferredcites →https://doi.org/10.3945/ajcn.112.037663openalex-snapshot
What is the evidence that vitamin C supplements lower blood pressure?
inferredcites →https://doi.org/10.4330/wjc.v6.i6.353openalex-snapshot
Essential hypertension and oxidative stress: New insights
inferredcites →https://doi.org/10.5808/gi.2012.10.4.244openalex-snapshot
Association Analysis of Reactive Oxygen Species-Hypertension Genes Discovered by Literature Mining
inferredcites →https://doi.org/10.7326/0003-4819-142-1-200501040-00110openalex-snapshot
Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Therapeutic potency of a developed optimized polyherbal formulation in ameliorating obesity induced inflammation and oxidative stress in Swiss albino mice by targeting PPARγ, insulin receptor and AMPK signalling pathway
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Dihydrotanshinone I ameliorated angiotensin II-induced mitochondrial damage and oxidative stress in vascular smooth muscle cells
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Oxytetracycline-induced oxidative liver damage by disturbed mitochondrial dynamics and impaired enzyme antioxidants in largemouth bass (Micropterus salmoides)
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TANK-binding kinase 1 inhibitor GSK8612 suppresses platelet function and thrombosis via the ERK/P38 signaling pathway
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Qingda granule attenuates angiotensin II-induced cardiac hypertrophy and apoptosis and modulates the PI3K/AKT pathway
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Melatonin improves arsenic-induced hypertension through the inactivation of the Sirt1/autophagy pathway in rat
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The mechanism of low-level arsenic exposure-induced hypertension: Inhibition of the activity of the angiotensin-converting enzyme 2
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CAMK1D and PI3 in low-density neutrophils are associated with the anti-hypertensive effects of valsartan
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Environmental contaminant body burdens and the relationship with blood pressure measures among Indigenous adolescents using Bayesian Kernel Machine Regression: Results from the Nituuchischaayihtitaau Aschii: Multi-Community Environment-and-Health Study in Eeyou Istchee, Quebec, Canada, 2005–2009
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Functional potato bioactive peptide intensifies Nrf2-dependent antioxidant defense against renal damage in hypertensive rats
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Sestrin 2, a potential star of antioxidant stress in cardiovascular diseases
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Mitochondrial hyperfusion induces metabolic remodeling in lung endothelial cells by modifying the activities of electron transport chain complexes I and III
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BRD4 expression in patients with essential hypertension and its effect on blood pressure in spontaneously hypertensive rats
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Integrating network pharmacology and non-targeted metabolomics to explore the common mechanism of Coptis Categorized Formula improving T2DM zebrafish
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Lycopene-supplemented diet ameliorates metabolic syndrome induced by fructose in rats
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The soybean bioactive peptide VHVV alleviates hypertension-induced renal damage in hypertensive rats via the SIRT1-PGC1α/Nrf2 pathway
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The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence
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Unexpected oxidation of nitrendipine. Properties of oxidized nitrendipine and its Cu(II) complex
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A redox-sensitive coating with disulfide bonds is a promising candidate for surface-modified interventional devices
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Effects of virgin coconut oil consumption on metabolic syndrome components and asymmetric dimethylarginine: A randomized controlled clinical trial
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Ischemic injury precipitates neuronal vulnerability in Parkinson's disease: Insights from PINK1 mouse model study and clinical retrospective data
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G-protein coupled receptor 30 attenuates myocardial hypertrophy by reducing oxidative stress and apoptosis in Ang II-treated mice
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γ-Pyrone compounds: flavonoids and maltol glucoside derivatives from Herniaria glabra L. collected in the Ternopil region of the Ukraine
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Reactive oxygen species in thoracic aortic dissection: Insights into mechanisms and disease progression
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Oxidative stress and vascular stiffness in hypertension: A renewed interest for antioxidant therapies?
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Maternal high-salt diet alters redox state and mitochondrial function in newborn rat offspring’s brain
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Genetic polymorphisms associated with reactive oxygen species and blood pressure regulation
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Redox status of patients before cardiac surgery
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Recapitulate genistein for topical applications including nanotechnology delivery
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Renal Dopamine Receptors and Oxidative Stress: Role in Hypertension
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Chronic Treatment With Acetylcholinesterase Inhibitors Attenuates Vascular Dysfunction in Spontaneously Hypertensive Rats
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Exosomal microRNAs in the development of essential hypertension and its potential as biomarkers
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Sex, Oxidative Stress, and Hypertension: Insights From Animal Models
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Oxidative Stress Markers Differ in Two Placental Dysfunction Pathologies: Pregnancy-Induced Hypertension and Intrauterine Growth Restriction
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Fibulin-3 Attenuates Phosphate-Induced Vascular Smooth Muscle Cell Calcification by Inhibition of Oxidative Stress
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DRD4 (Dopamine D4 Receptor) Mitigate Abdominal Aortic Aneurysm via Decreasing P38 MAPK (mitogen-activated protein kinase)/NOX4 (NADPH Oxidase 4) Axis–Associated Oxidative Stress
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Endothelial Dysfunction and Its Clinical Implications
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Role of copper and its complexes in cardiovascular diseases.
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Increased plasma disequilibrium between pro- and anti-oxidants during the early phase resuscitation after cardiac arrest is associated with increased levels of oxidative stress end-products
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Protective effects of the R-(+)-thioctic acid treatment: possible anti-inflammatory activity on heart of hypertensive rats
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Evaluation of Oxidative Stress Markers in Relation APGAR Scores to in Egyptian Newborns with Intrauterine Growth Retardation
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Role of Mitophagy in Cardiovascular Disease
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Piperazine ferulate exerts antihypertensive effect and improves endothelial function in vitro and in vivo via the activation of endothelial nitric oxide synthase
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Differential platelet oxidation-inflammatory phenotype in coronary artery disease versus peripheral artery disease supports diverse pathophysiological processes
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Alleviation of Angiotensin II-Induced Vascular Endothelial Cell Injury Through Long Non-coding RNA TUG1 Inhibition
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Isolated Natural Antioxidants as a new Possible Therapeutic Alternative for the Treatment of Hypertension
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Nuclear receptor subfamily 4 group a member 1 eases angiotensin II-arose oxidative stress in vascular smooth muscle cell by boosting nucleotide-binding oligomerization domain-like receptor family caspase recruitment domain containing 3 transcription
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Possibilities of carboxytherapy for diseases of the cardiovascular system
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Unilateral Ureteral Obstruction as a Model of Kidney Fibrosis and Increasing of Systolic Blood Pressure in Mice
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Identification of Significant Proteins in Hypertension Using The Clustering Molecular Complex Detection (MCODE) Method
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Emerging role of exosomes in vascular diseases
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An Overview of Vascular Dysfunction and Determinants: The Case of Children of African Ancestry
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Coordinated Contribution of NADPH Oxidase- and Mitochondria-Derived Reactive Oxygen Species in Metabolic Syndrome and Its Implication in Renal Dysfunction
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Oxidative Stress: A Major Player in Cerebrovascular Alterations Associated to Neurodegenerative Events
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Chronic Metabolic Acidosis Elicits Hypertension via Upregulation of Intrarenal Angiotensin II and Induction of Oxidative Stress
inferred← citeshttps://doi.org/10.3390/antiox11081541openalex-snapshot
The Prognostic Value of Derivatives-Reactive Oxygen Metabolites (d-ROMs) for Cardiovascular Disease Events and Mortality: A Review
inferred← citeshttps://doi.org/10.3390/antiox11122432openalex-snapshot
Oxidative Regulation of Vascular Cav1.2 Channels Triggers Vascular Dysfunction in Hypertension-Related Disorders
inferred← citeshttps://doi.org/10.3390/antiox12101856openalex-snapshot
Optogenetics in Alzheimer’s Disease: Focus on Astrocytes
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Redox Imbalances in Ageing and Metabolic Alterations: Implications in Cancer and Cardiac Diseases. An Overview from the Working Group of Cardiotoxicity and Cardioprotection of the Italian Society of Cardiology (SIC)
inferred← citeshttps://doi.org/10.3390/biom15060892openalex-snapshot
Calcium Signaling Dynamics in Vascular Cells and Their Dysregulation in Vascular Disease
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Polyphenols as Antioxidants for Extending Food Shelf-Life and in the Prevention of Health Diseases: Encapsulation and Interfacial Phenomena
inferred← citeshttps://doi.org/10.3390/cimb44050144openalex-snapshot
Inhibition of eNOS Partially Blunts the Beneficial Effects of Nebivolol on Angiotensin II-Induced Signaling in H9c2 Cardiomyoblasts
inferred← citeshttps://doi.org/10.3390/ijms22010056openalex-snapshot
Human Nitric Oxide Synthase—Its Functions, Polymorphisms, and Inhibitors in the Context of Inflammation, Diabetes and Cardiovascular Diseases
inferred← citeshttps://doi.org/10.3390/ijms24032228openalex-snapshot
The Mycotoxin Patulin Inhibits the Mitochondrial Carnitine/Acylcarnitine Carrier (SLC25A20) by Interaction with Cys136 Implications for Human Health
inferred← citeshttps://doi.org/10.3390/ijms26189227openalex-snapshot
Inhibition of HCN Channels Enhances Oxidative Stress and Autophagy of NRK-52E Cells Under NH4Cl Treatment
inferred← citeshttps://doi.org/10.3390/jpm12091531openalex-snapshot
Application of Reactive Oxygen Species in Dental Treatment
inferred← citeshttps://doi.org/10.3390/life13010043openalex-snapshot
Parkia speciosa Hassk. Empty Pod Extract Prevents Cardiomyocyte Hypertrophy by Inhibiting MAPK and Calcineurin-NFATC3 Signaling Pathways
inferred← citeshttps://doi.org/10.3390/md19110609openalex-snapshot
Cytoprotective Peptides from Blue Mussel Protein Hydrolysates: Identification and Mechanism Investigation in Human Umbilical Vein Endothelial Cells Injury
inferred← citeshttps://doi.org/10.3390/medicina56120704openalex-snapshot
Association between Light-Induced Dynamic Dilation of Retinal Vessels and Echocardiographic Parameters of the Left Ventricular Function in Hypertensive Patients
inferred← citeshttps://doi.org/10.3390/molecules26133795openalex-snapshot
Cytoprotective Mechanisms of DJ-1: Implications in Cardiac Pathophysiology
inferred← citeshttps://doi.org/10.3390/molecules28207209openalex-snapshot
Potential Benefits of Antioxidant Phytochemicals in Type 2 Diabetes
inferred← citeshttps://doi.org/10.3390/nu12092785openalex-snapshot
Nutrition, Bioenergetics, and Metabolic Syndrome
inferred← citeshttps://doi.org/10.3390/pharmaceutics14030534openalex-snapshot
Oxidative Stress in Arterial Hypertension (HTN): The Nuclear Factor Erythroid Factor 2-Related Factor 2 (Nrf2) Pathway, Implications and Future Perspectives
inferred← citeshttps://doi.org/10.37349/emed.2022.00074openalex-snapshot
Oxidative stress in obesity and insulin resistance
inferred← citeshttps://doi.org/10.3892/ijmm.2025.5500openalex-snapshot
Thymoquinone mitigates cardiac hypertrophy by activating adaptive autophagy via the PPAR‑γ/14‑3‑3γ pathway
inferred← citeshttps://doi.org/10.47363/pms/2021(5)165openalex-snapshot
Effects of Methanol Fraction of Anarcardium Occidentale (Cashew) Bark Extract on SaltInduced Hypertension in Rats
inferred← citeshttps://doi.org/10.47760/ijpsm.2020.v05i10.001openalex-snapshot
Antioxidant Activities of Genistein: A Review
inferred← citeshttps://doi.org/10.47829/ajsccr.2020.2601openalex-snapshot
A New Radically Improved Model of the Circulation With Important Clinical Implications
inferred← citeshttps://doi.org/10.52571/ptq.v17.n34.2020.502_p34_pgs_478_501.pdfopenalex-snapshot
APOCYNIN, AN INHIBITOR OF THE NADPH OXIDASE COMPLEX
inferred← citeshttps://doi.org/10.5937/afmnai37-27103openalex-snapshot
In vitro antioxidant properties of 2-imino-benzimidazole and 1,3-thiazolo[3,2-a]benzimidazolone derivatives
inferred← citeshttps://doi.org/10.6084/m9.figshare.26367920openalex-snapshot
Additional file 1 of Protective effects of the R-(+)-thioctic acid treatment: possible anti-inflammatory activity on heart of hypertensive rats
inferred← citeshttps://doi.org/10.6084/m9.figshare.26368524openalex-snapshot
Additional file 2 of Protective effects of the R-(+)-thioctic acid treatment: possible anti-inflammatory activity on heart of hypertensive rats
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