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Lipid Metabolism and Cancer Immunotherapy: Immunosuppressive Myeloid Cells at the Crossroad
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Oxysterol mixture and, in particular, 27‐hydroxycholesterol drive M2 polarization of human macrophages
inferredcites →https://doi.org/10.1002/jcp.26075openalex-snapshot
Myeloid‐derived suppressor cells: Important contributors to tumor progression and metastasis
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Frontline Science: High fat diet and leptin promote tumor progression by inducing myeloid-derived suppressor cells
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The effect of palmitic acid on inflammatory response in macrophages: an overview of molecular mechanisms
inferredcites →https://doi.org/10.1007/s00262-008-0523-4openalex-snapshot
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy
inferredcites →https://doi.org/10.1007/s00262-011-1028-0openalex-snapshot
Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13
inferredcites →https://doi.org/10.1007/s00262-012-1324-3openalex-snapshot
Rosiglitazone and Gemcitabine in combination reduces immune suppression and modulates T cell populations in pancreatic cancer
inferredcites →https://doi.org/10.1007/s00262-013-1396-8openalex-snapshot
Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer
inferredcites →https://doi.org/10.1007/s00262-014-1527-xopenalex-snapshot
Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer
inferredcites →https://doi.org/10.1007/s00262-014-1549-4openalex-snapshot
Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer
inferredcites →https://doi.org/10.1007/s00262-017-1966-2openalex-snapshot
Myeloid cells as a target for oligonucleotide therapeutics: turning obstacles into opportunities
inferredcites →https://doi.org/10.1007/s00262-018-2175-3openalex-snapshot
Targeting myeloid-derived suppressor cells for cancer immunotherapy
inferredcites →https://doi.org/10.1007/s40487-018-0089-zopenalex-snapshot
The Role of Interleukin-1 in the Pathogenesis of Cancer and its Potential as a Therapeutic Target in Clinical Practice
inferredcites →https://doi.org/10.1016/b978-0-12-407190-2.00007-1openalex-snapshot
Therapeutic Cancer Vaccines
inferredcites →https://doi.org/10.1016/b978-012095440-7/50022-6openalex-snapshot
Lipids III: Plasma Lipoproteins
inferredcites →https://doi.org/10.1016/bs.ircmb.2017.07.004openalex-snapshot
Indoleamine 2,3-Dioxygenase and Its Therapeutic Inhibition in Cancer
inferredcites →https://doi.org/10.1016/j.bbalip.2014.06.007openalex-snapshot
Fatty acid oxidation is dispensable for human macrophage IL-4-induced polarization
inferredcites →https://doi.org/10.1016/j.bbrc.2013.09.037openalex-snapshot
ATP-citrate lyase is essential for macrophage inflammatory response
inferredcites →https://doi.org/10.1016/j.biopha.2019.109458openalex-snapshot
Metformin inhibits the function of granulocytic myeloid-derived suppressor cells in tumor-bearing mice
inferredcites →https://doi.org/10.1016/j.ccell.2015.03.001openalex-snapshot
Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
inferredcites →https://doi.org/10.1016/j.ccell.2015.07.006openalex-snapshot
RORC1 Regulates Tumor-Promoting “Emergency” Granulo-Monocytopoiesis
inferredcites →https://doi.org/10.1016/j.ccell.2016.05.017openalex-snapshot
The Multifaceted Role of Perivascular Macrophages in Tumors
inferredcites →https://doi.org/10.1016/j.ccell.2017.10.005openalex-snapshot
Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors
inferredcites →https://doi.org/10.1016/j.ccell.2018.09.003openalex-snapshot
Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy
inferredcites →https://doi.org/10.1016/j.ccell.2019.02.009openalex-snapshot
Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets
inferredcites →https://doi.org/10.1016/j.cell.2011.02.013openalex-snapshot
Hallmarks of Cancer: The Next Generation
inferredcites →https://doi.org/10.1016/j.cell.2012.10.028openalex-snapshot
Convergent Multi-miRNA Targeting of ApoE Drives LRP1/LRP8-Dependent Melanoma Metastasis and Angiogenesis
inferredcites →https://doi.org/10.1016/j.cell.2015.08.016openalex-snapshot
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
inferredcites →https://doi.org/10.1016/j.cell.2015.11.045openalex-snapshot
Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling
inferredcites →https://doi.org/10.1016/j.cell.2017.01.016openalex-snapshot
The Principles of Engineering Immune Cells to Treat Cancer
inferredcites →https://doi.org/10.1016/j.cell.2017.01.017openalex-snapshot
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
inferredcites →https://doi.org/10.1016/j.cell.2017.12.013openalex-snapshot
Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming
inferredcites →https://doi.org/10.1016/j.cell.2017.12.025openalex-snapshot
An Integrated View of Immunometabolism
inferredcites →https://doi.org/10.1016/j.cell.2017.12.026openalex-snapshot
LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer
inferredcites →https://doi.org/10.1016/j.cellimm.2018.01.020openalex-snapshot
Macrophages and lipid metabolism
inferredcites →https://doi.org/10.1016/j.cellimm.2018.02.008openalex-snapshot
Myeloid cell heterogeneity in cancer: not a single cell alike
inferredcites →https://doi.org/10.1016/j.celrep.2015.02.024openalex-snapshot
M-CSF from Cancer Cells Induces Fatty Acid Synthase and PPARβ/δ Activation in Tumor Myeloid Cells, Leading to Tumor Progression
inferredcites →https://doi.org/10.1016/j.celrep.2016.09.008openalex-snapshot
Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages
inferredcites →https://doi.org/10.1016/j.celrep.2016.10.052openalex-snapshot
Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies
inferredcites →https://doi.org/10.1016/j.cmet.2011.04.001openalex-snapshot
Linking Lipid Metabolism to the Innate Immune Response in Macrophages through Sterol Regulatory Element Binding Protein-1a
inferredcites →https://doi.org/10.1016/j.cmet.2013.11.017openalex-snapshot
Local Proliferation of Macrophages Contributes to Obesity-Associated Adipose Tissue Inflammation
inferredcites →https://doi.org/10.1016/j.cmet.2014.04.010openalex-snapshot
Obesity Corrupts Myelopoiesis
inferredcites →https://doi.org/10.1016/j.cmet.2017.06.004openalex-snapshot
Similarities and Distinctions of Cancer and Immune Metabolism in Inflammation and Tumors
inferredcites →https://doi.org/10.1016/j.cmet.2018.06.001openalex-snapshot
Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis
inferredcites →https://doi.org/10.1016/j.cmet.2019.02.016openalex-snapshot
Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression
inferredcites →https://doi.org/10.1016/j.cmet.2019.04.002openalex-snapshot
Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment
inferredcites →https://doi.org/10.1016/j.cmet.2019.05.011openalex-snapshot
Membrane Cholesterol Regulates Macrophage Plasticity in Cancer
inferredcites →https://doi.org/10.1016/j.cmet.2019.05.014openalex-snapshot
Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia
inferredcites →https://doi.org/10.1016/j.cmet.2019.07.015openalex-snapshot
Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer
inferredcites →https://doi.org/10.1016/j.humimm.2009.02.008openalex-snapshot
Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation
inferredcites →https://doi.org/10.1016/j.immuni.2010.05.010openalex-snapshot
Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor
inferredcites →https://doi.org/10.1016/j.immuni.2015.09.001openalex-snapshot
Metabolic Reprogramming of Immune Cells in Cancer Progression
inferredcites →https://doi.org/10.1016/j.immuni.2017.07.014openalex-snapshot
Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression
inferredcites →https://doi.org/10.1016/j.immuni.2017.09.008openalex-snapshot
Monocyte-Macrophages and T Cells in Atherosclerosis
inferredcites →https://doi.org/10.1016/j.immuni.2019.12.011openalex-snapshot
Top 10 Challenges in Cancer Immunotherapy
inferredcites →https://doi.org/10.1016/j.intimp.2011.03.003openalex-snapshot
Myeloid cell population dynamics in healthy and tumor-bearing mice
inferredcites →https://doi.org/10.1016/j.it.2011.01.004openalex-snapshot
Cytokines and the inception of CD8 T cell responses
inferredcites →https://doi.org/10.1016/j.it.2017.05.006openalex-snapshot
Integrating Next-Generation Dendritic Cell Vaccines into the Current Cancer Immunotherapy Landscape
inferredcites →https://doi.org/10.1016/j.it.2019.02.003openalex-snapshot
Targeting Tumor-Associated Macrophages in Cancer
inferredcites →https://doi.org/10.1016/j.jid.2017.03.033openalex-snapshot
Phenformin Inhibits Myeloid-Derived Suppressor Cells and Enhances the Anti-Tumor Activity of PD-1 Blockade in Melanoma
inferredcites →https://doi.org/10.1016/j.mam.2011.04.005openalex-snapshot
Macrophage regulation of tumor angiogenesis: Implications for cancer therapy
inferredcites →https://doi.org/10.1016/j.mce.2012.06.007openalex-snapshot
Regulation of cholesterol homeostasis
inferredcites →https://doi.org/10.1016/j.molcel.2018.07.030openalex-snapshot
Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
inferredcites →https://doi.org/10.1016/j.molmed.2019.02.007openalex-snapshot
Pharmacological Modulation of the STING Pathway for Cancer Immunotherapy
inferredcites →https://doi.org/10.1016/j.semcancer.2017.10.001openalex-snapshot
Emerging targets in cancer immunotherapy
inferredcites →https://doi.org/10.1016/s1471-4906(02)02302-5openalex-snapshot
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
inferredcites →https://doi.org/10.1038/nature07202openalex-snapshot
Integration of metabolism and inflammation by lipid-activated nuclear receptors
inferredcites →https://doi.org/10.1038/nature11986openalex-snapshot
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
inferredcites →https://doi.org/10.1038/nature13862openalex-snapshot
Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis
inferredcites →https://doi.org/10.1038/nature17412openalex-snapshot
Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism
inferredcites →https://doi.org/10.1038/nature19834openalex-snapshot
PI3Kγ is a molecular switch that controls immune suppression
inferredcites →https://doi.org/10.1038/nature20554openalex-snapshot
Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells
inferredcites →https://doi.org/10.1038/nature21363openalex-snapshot
Inflammation, metaflammation and immunometabolic disorders
inferredcites →https://doi.org/10.1038/nature21409openalex-snapshot
Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages
inferredcites →https://doi.org/10.1038/ncb3493openalex-snapshot
Human haematopoietic stem cell lineage commitment is a continuous process
inferredcites →https://doi.org/10.1038/ncb3578openalex-snapshot
Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF
inferredcites →https://doi.org/10.1038/ncomms12150openalex-snapshot
Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
inferredcites →https://doi.org/10.1038/ncomms7354openalex-snapshot
The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity
inferredcites →https://doi.org/10.1038/ni.1937openalex-snapshot
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
inferredcites →https://doi.org/10.1038/ni.2956openalex-snapshot
Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
inferredcites →https://doi.org/10.1038/ni.3366openalex-snapshot
Fatty acid oxidation in macrophage polarization
inferredcites →https://doi.org/10.1038/nm.2074openalex-snapshot
Tumor-mediated liver X receptor-α activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses
inferredcites →https://doi.org/10.1038/nm.2172openalex-snapshot
Lipid accumulation and dendritic cell dysfunction in cancer
inferredcites →https://doi.org/10.1038/nm1100openalex-snapshot
Cancer immunotherapy: moving beyond current vaccines
inferredcites →https://doi.org/10.1038/nrc.2016.54openalex-snapshot
The role of myeloid cells in cancer therapies
inferredcites →https://doi.org/10.1038/nrc.2017.51openalex-snapshot
Microenvironmental regulation of tumour angiogenesis
inferredcites →https://doi.org/10.1038/nrc1256openalex-snapshot
Tumour-educated macrophages promote tumour progression and metastasis
inferredcites →https://doi.org/10.1038/nrc2355openalex-snapshot
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
inferredcites →https://doi.org/10.1038/nrc3958openalex-snapshot
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
inferredcites →https://doi.org/10.1038/nrcardio.2014.173openalex-snapshot
Macrophage subsets in atherosclerosis
inferredcites →https://doi.org/10.1038/nrclinonc.2016.217openalex-snapshot
Tumour-associated macrophages as treatment targets in oncology
inferredcites →https://doi.org/10.1038/nrclinonc.2016.25openalex-snapshot
The future of cancer treatment: immunomodulation, CARs and combination immunotherapy
inferredcites →https://doi.org/10.1038/nrclinonc.2016.60openalex-snapshot
Cancer metabolism: a therapeutic perspective
inferredcites →https://doi.org/10.1038/nrendo.2017.90openalex-snapshot
Adapting to obesity with adipose tissue inflammation
inferredcites →https://doi.org/10.1038/nri.2016.70openalex-snapshot
A guide to immunometabolism for immunologists
inferredcites →https://doi.org/10.1038/nri1961openalex-snapshot
Interferons, immunity and cancer immunoediting
inferredcites →https://doi.org/10.1038/nri3088openalex-snapshot
Transcriptional regulation of macrophage polarization: enabling diversity with identity
inferredcites →https://doi.org/10.1038/nri3175openalex-snapshot
Coordinated regulation of myeloid cells by tumours
inferredcites →https://doi.org/10.1038/nri3755openalex-snapshot
25-Hydroxycholesterols in innate and adaptive immunity
inferredcites →https://doi.org/10.1038/nri3793openalex-snapshot
Cholesterol, inflammation and innate immunity
inferredcites →https://doi.org/10.1038/s41392-019-0070-9openalex-snapshot
Genetically engineered T cells for cancer immunotherapy
inferredcites →https://doi.org/10.1038/s41416-018-0188-5openalex-snapshot
STING agonist therapy in combination with PD-1 immune checkpoint blockade enhances response to carboplatin chemotherapy in high-grade serous ovarian cancer
inferredcites →https://doi.org/10.1038/s41416-018-0328-yopenalex-snapshot
Cytokines in clinical cancer immunotherapy
inferredcites →https://doi.org/10.1038/s41419-019-2109-9openalex-snapshot
The differential statin effect on cytokine production of monocytes or macrophages is mediated by differential geranylgeranylation-dependent Rac1 activation
inferredcites →https://doi.org/10.1038/s41467-017-00910-zopenalex-snapshot
The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells
inferredcites →https://doi.org/10.1038/s41467-017-01566-5openalex-snapshot
Host STING-dependent MDSC mobilization drives extrinsic radiation resistance
inferredcites →https://doi.org/10.1038/s41467-019-11788-4openalex-snapshot
Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry
inferredcites →https://doi.org/10.1038/s41577-019-0127-6openalex-snapshot
Macrophages as regulators of tumour immunity and immunotherapy
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Fatty acid transport protein 2 reprograms neutrophils in cancer
inferredcites →https://doi.org/10.1038/s41587-020-0462-yopenalex-snapshot
Human chimeric antigen receptor macrophages for cancer immunotherapy
inferredcites →https://doi.org/10.1038/s41590-018-0251-7openalex-snapshot
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
inferredcites →https://doi.org/10.1038/s41590-018-0292-yopenalex-snapshot
Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal
inferredcites →https://doi.org/10.1038/s41590-019-0539-2openalex-snapshot
Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation
inferredcites →https://doi.org/10.1038/s41591-018-0014-xopenalex-snapshot
Understanding the tumor immune microenvironment (TIME) for effective therapy
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Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade
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Oleate but not stearate induces the regulatory phenotype of myeloid suppressor cells
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Cholesterol metabolism in cancer: mechanisms and therapeutic opportunities
inferredcites →https://doi.org/10.1038/sj.onc.1210764openalex-snapshot
Transcriptional control of granulocyte and monocyte development
inferredcites →https://doi.org/10.1038/srep19694openalex-snapshot
Obesity is associated with changes in oxysterol metabolism and levels in mice liver, hypothalamus, adipose tissue and plasma
inferredcites →https://doi.org/10.1038/srep29719openalex-snapshot
CD47 Promotes Tumor Invasion and Metastasis in Non-small Cell Lung Cancer
inferredcites →https://doi.org/10.1042/bst20150255openalex-snapshot
Current trends in oxysterol research
inferredcites →https://doi.org/10.1056/nejmc062714openalex-snapshot
Use of Statins and Outcome of BCG Treatment for Bladder Cancer
inferredcites →https://doi.org/10.1056/nejmc1214827openalex-snapshot
Statin use and reduced cancer-related mortality...N Engl J Med. 2012 Nov 8;367(19): 1792-802
inferredcites →https://doi.org/10.1056/nejmoa1201735openalex-snapshot
Statin Use and Reduced Cancer-Related Mortality
inferredcites →https://doi.org/10.1056/nejmoa1707447openalex-snapshot
Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma
inferredcites →https://doi.org/10.1056/nejmoa1709866openalex-snapshot
Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
inferredcites →https://doi.org/10.1056/nejmra1703481openalex-snapshot
Immune-Related Adverse Events Associated with Immune Checkpoint Blockade
inferredcites →https://doi.org/10.1073/pnas.1113744109openalex-snapshot
Origins of tumor-associated macrophages and neutrophils
inferredcites →https://doi.org/10.1073/pnas.1320753111openalex-snapshot
Circulating hematopoietic stem and progenitor cells are myeloid-biased in cancer patients
inferredcites →https://doi.org/10.1073/pnas.1612920114openalex-snapshot
COX2/mPGES1/PGE 2 pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells
inferredcites →https://doi.org/10.1074/jbc.m109.047472openalex-snapshot
The Macrophage Cholesterol Exporter ABCA1 Functions as an Anti-inflammatory Receptor
inferredcites →https://doi.org/10.1074/jbc.m113.468967openalex-snapshot
The Cardioprotective Protein Apolipoprotein A1 Promotes Potent Anti-tumorigenic Effects
inferredcites →https://doi.org/10.1074/jbc.ra119.008680openalex-snapshot
Mitochondrial fatty acid oxidation and the electron transport chain comprise a multifunctional mitochondrial protein complex
inferredcites →https://doi.org/10.1080/13543784.2017.1351941openalex-snapshot
Do STAT3 inhibitors have potential in the future for cancer therapy?
inferredcites →https://doi.org/10.1080/14737140.2017.1364995openalex-snapshot
Anti-GD2 immunotherapy for neuroblastoma
inferredcites →https://doi.org/10.1080/2162402x.2014.998529openalex-snapshot
MyeloidSTAT3promotes formation of colitis-associated colorectal cancer in mice
inferredcites →https://doi.org/10.1080/2162402x.2015.1008371openalex-snapshot
Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment
inferredcites →https://doi.org/10.1080/2162402x.2015.1074374openalex-snapshot
Hydrogel dual delivered celecoxib and anti-PD-1 synergistically improve antitumor immunity
inferredcites →https://doi.org/10.1080/2162402x.2017.1334744openalex-snapshot
Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages
inferredcites →https://doi.org/10.1080/2162402x.2017.1344804openalex-snapshot
Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells
inferredcites →https://doi.org/10.1080/2162402x.2018.1442167openalex-snapshot
Metformin blocks myeloid-derived suppressor cell accumulation through AMPK-DACH1-CXCL1 axis
inferredcites →https://doi.org/10.1084/jem.20130440openalex-snapshot
The oxysterol–CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils
inferredcites →https://doi.org/10.1084/jem.20180534openalex-snapshot
Macrophages of distinct origins contribute to tumor development in the lung
inferredcites →https://doi.org/10.1084/jem.20191869openalex-snapshot
Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer
inferredcites →https://doi.org/10.1093/bioinformatics/btt469openalex-snapshot
A combined omics study on activated macrophages—enhanced role of STATs in apoptosis, immunity and lipid metabolism
inferredcites →https://doi.org/10.1093/carcin/bgy088openalex-snapshot
Metabolic influence on the differentiation of suppressive myeloid cells in cancer
inferredcites →https://doi.org/10.1093/jnci/djy115openalex-snapshot
Circulating 27-Hydroxycholesterol and Breast Cancer Risk: Results From the EPIC-Heidelberg Cohort
inferredcites →https://doi.org/10.1093/jncics/pkz101openalex-snapshot
Reduced Protumorigenic Tumor-Associated Macrophages With Statin Use in Premalignant Human Lung Adenocarcinoma
inferredcites →https://doi.org/10.1093/qjmed/hcr243openalex-snapshot
The statin-low cholesterol-cancer conundrum
inferredcites →https://doi.org/10.1097/01.mol.0000180166.08196.07openalex-snapshot
The role of fatty acid binding proteins in metabolic syndrome and atherosclerosis
inferredcites →https://doi.org/10.1097/ccm.0000000000002053openalex-snapshot
Cytokine Release Syndrome After Chimeric Antigen Receptor T Cell Therapy for Acute Lymphoblastic Leukemia
inferredcites →https://doi.org/10.1111/imm.12902openalex-snapshot
Immune modulatory effects of statins
inferredcites →https://doi.org/10.1111/j.1365-2567.2005.02181.xopenalex-snapshot
Developing dendritic cells become ‘lacy’ cells packed with fat and glycogen
inferredcites →https://doi.org/10.1111/j.1365-2567.2006.02366.xopenalex-snapshot
Tumoristatic effects of anti‐CD40 mAb‐activated macrophages involve nitric oxide and tumour necrosis factor‐α
inferredcites →https://doi.org/10.1111/j.1749-6632.2008.03691.xopenalex-snapshot
CCR5 Proinflammatory Allele in Prostate Cancer Risk
inferredcites →https://doi.org/10.1126/science.1241908openalex-snapshot
27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology
inferredcites →https://doi.org/10.1126/science.1252510openalex-snapshot
The cellular and molecular origin of tumor-associated macrophages
inferredcites →https://doi.org/10.1126/science.aaa4967openalex-snapshot
Adoptive cell transfer as personalized immunotherapy for human cancer
inferredcites →https://doi.org/10.1126/science.aac7801openalex-snapshot
Neutrophil-macrophage communication in inflammation and atherosclerosis
inferredcites →https://doi.org/10.1126/science.aar4060openalex-snapshot
Cancer immunotherapy using checkpoint blockade
inferredcites →https://doi.org/10.1126/sciimmunol.aaf8943openalex-snapshot
Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients
inferredcites →https://doi.org/10.1126/sciimmunol.aay1863openalex-snapshot
Targeted deletion of PD-1 in myeloid cells induces antitumor immunity
inferredcites →https://doi.org/10.1136/esmoopen-2017-000213openalex-snapshot
Mechanisms of action and rationale for the use of checkpoint inhibitors in cancer
inferredcites →https://doi.org/10.1146/annurev-med-050913-022228openalex-snapshot
Obesity and Cancer: Local and Systemic Mechanisms
inferredcites →https://doi.org/10.1146/annurev-med-051013-052304openalex-snapshot
Regulation of Tumor Metastasis by Myeloid-Derived Suppressor Cells
inferredcites →https://doi.org/10.1146/annurev-pathol-011110-130138openalex-snapshot
Alternative Macrophage Activation and Metabolism
inferredcites →https://doi.org/10.1146/annurev.physiol.69.031905.160725openalex-snapshot
Regulation of Intestinal Cholesterol Absorption
inferredcites →https://doi.org/10.1158/0008-5472.can-09-2587openalex-snapshot
Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine
inferredcites →https://doi.org/10.1158/0008-5472.can-09-4672openalex-snapshot
Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes
inferredcites →https://doi.org/10.1158/0008-5472.can-10-1921openalex-snapshot
The Inflammasome Component Nlrp3 Impairs Antitumor Vaccine by Enhancing the Accumulation of Tumor-Associated Myeloid-Derived Suppressor Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-10-1968openalex-snapshot
IL-2 Costimulation Enables Statin-Mediated Activation of Human NK Cells, Preferentially through a Mechanism Involving CD56+ Dendritic Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-11-1261openalex-snapshot
Tumor-Associated Macrophages Mediate Immunosuppression in the Renal Cancer Microenvironment by Activating the 15-Lipoxygenase-2 Pathway
inferredcites →https://doi.org/10.1158/0008-5472.can-11-1792openalex-snapshot
Monocytic CCR2+ Myeloid-Derived Suppressor Cells Promote Immune Escape by Limiting Activated CD8 T-cell Infiltration into the Tumor Microenvironment
inferredcites →https://doi.org/10.1158/0008-5472.can-13-2689openalex-snapshot
Fatty Acid-Binding Protein E-FABP Restricts Tumor Growth by Promoting IFN-β Responses in Tumor-Associated Macrophages
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CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models
inferredcites →https://doi.org/10.1158/0008-5472.can-14-1491openalex-snapshot
l -Arginine Depletion Blunts Antitumor T-cell Responses by Inducing Myeloid-Derived Suppressor Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-15-2613openalex-snapshot
The Role of Cholesterol in Cancer
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CCR5+ Myeloid-Derived Suppressor Cells Are Enriched and Activated in Melanoma Lesions
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Metformin-Induced Reduction of CD39 and CD73 Blocks Myeloid-Derived Suppressor Cell Activity in Patients with Ovarian Cancer
inferredcites →https://doi.org/10.1158/0008-5472.can-18-1367openalex-snapshot
Diverse Functions of Macrophages in Different Tumor Microenvironments
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The Tumor Microenvironment Innately Modulates Cancer Progression
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Tumor-Derived Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic MDSCs
inferredcites →https://doi.org/10.1158/1078-0432.ccr-10-1114openalex-snapshot
Direct Effects of Type I Interferons on Cells of the Immune System
inferredcites →https://doi.org/10.1158/1078-0432.ccr-13-1016openalex-snapshot
Interleukin-7 Mediates Selective Expansion of Tumor-redirected Cytotoxic T Lymphocytes (CTLs) without Enhancement of Regulatory T-cell Inhibition
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Safety, Correlative Markers, and Clinical Results of Adjuvant Nivolumab in Combination with Vaccine in Resected High-Risk Metastatic Melanoma
inferredcites →https://doi.org/10.1158/1078-0432.ccr-14-2742openalex-snapshot
Myeloid-Derived Suppressor Cells as an Immune Parameter in Patients with Concurrent Sunitinib and Stereotactic Body Radiotherapy
inferredcites →https://doi.org/10.1158/1078-0432.ccr-16-1700openalex-snapshot
TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding
inferredcites →https://doi.org/10.1158/1078-0432.ccr-17-0741openalex-snapshot
Entinostat Neutralizes Myeloid-Derived Suppressor Cells and Enhances the Antitumor Effect of PD-1 Inhibition in Murine Models of Lung and Renal Cell Carcinoma
inferredcites →https://doi.org/10.1158/1078-0432.ccr-17-2871openalex-snapshot
CAR T-Cell Therapies in Glioblastoma: A First Look
inferredcites →https://doi.org/10.1158/1538-7445.am2011-3649openalex-snapshot
Abstract 3649: Contribution of fatty acid accumulation to myeloid-derived suppressor cell function in cancer
inferredcites →https://doi.org/10.1158/1940-6207.capr-12-0140openalex-snapshot
Obesity, Energy Balance, and Cancer: New Opportunities for Prevention
inferredcites →https://doi.org/10.1158/2159-8290.cd-15-1177openalex-snapshot
Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy
inferredcites →https://doi.org/10.1158/2326-6066.cir-15-0036openalex-snapshot
Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies
inferredcites →https://doi.org/10.1158/2326-6066.cir-16-0297openalex-snapshot
Myeloid-Derived Suppressor Cells
inferredcites →https://doi.org/10.1158/2326-6066.cir-17-0143openalex-snapshot
PI3Kγ Activates Integrin α4 and Promotes Immune Suppressive Myeloid Cell Polarization during Tumor Progression
inferredcites →https://doi.org/10.1158/2326-6066.cir-17-0612openalex-snapshot
PPARγ Contributes to Immunity Induced by Cancer Cell Vaccines That Secrete GM-CSF
inferredcites →https://doi.org/10.1159/000356856openalex-snapshot
Cholesterol: The Good, the Bad, and the Ugly - Therapeutic Targets for the Treatment of Dyslipidemia
showing the first 200 of 246 · page through all 246
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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The impact of lipids on the cancer–immunity cycle and strategies for modulating lipid metabolism to improve cancer immunotherapy
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Effect of metabolism on the immune microenvironment of breast cancer
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Modulation of PD-1/PD-L1 axis in myeloid-derived suppressor cells by anti-cancer treatments
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DHCR7 promotes tumorigenesis via activating PI3K/AKT/mTOR signalling pathway in bladder cancer
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MDSCs might be “Achilles heel” for eradicating CSCs
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Bulk and single-cell sequencing identified a prognostic model based on the macrophage and lipid metabolism related signatures for osteosarcoma patients
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Leucine-tRNA-synthetase-2-expressing B cells contribute to colorectal cancer immunoevasion
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The role of dendritic cells in cancer immunity and therapeutic strategies
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Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer
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Long-chain polyunsaturated lipids associated with responsiveness to anti-PD-1 therapy are colocalized with immune infiltrates in the tumor microenvironment
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Latest advances in tumor immunotherapy nanotechnology targeting cellular metabolic reprogramming and tumor microenvironment:A systematic review
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C3d(g), iron nanoparticles, hemin and cytochrome c may induce oxidative cytotoxicity in tumors and reduce tumor-associated myeloid cells-mediated immunosuppression
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Interplay of nutrient stress and lipid dynamics in colorectal cancer cells
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Therapeutic targeting of lipid metabolism in cancer: Mechanisms, pathways, and translational prospects
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Metabolic reprograming of MDSCs within tumor microenvironment and targeting for cancer immunotherapy
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Metabolic interplays between the tumour and the host shape the tumour macroenvironment
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Identification and immune landscape analysis of fatty acid metabolism genes related subtypes of gastric cancer
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A novel method for isolation of tumor infiltrating myeloid-derived suppressor cells from human lung tumor tissue
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Reprogramming and targeting of cholesterol metabolism in tumor-associated macrophages
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Efficacy of immunotherapy in obese patients with cancer
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Comprehensive identification of FoxO signaling as a promising prognostic and immunotherapeutic biomarker in glioma
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Construction and validation of a prognostic model based on anoikis-fatty acid metabolism-related genes in colorectal cancer: A retrospective cohort study
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Acquisition of an immunosuppressive microenvironment after CAR-T therapy drives T-cell dysfunction and resistance
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Acquisition of an immunosuppressive microenvironment after anti-CD19 CAR T-cell therapy is associated with T-cell dysfunction and resistance
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Data from Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
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Data from Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
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Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy
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The Diverse Roles of Lipid Metabolism Reprogramming in Shaping the Tumor Immune Microenvironment
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RORγ Bridges Cancer-Driven Lipid Dysmetabolism and Myeloid Immunosuppression
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The influence of nutritional status, lipid profile, leptin concentration and polymorphism of genes encoding leptin and neuropeptide Y on the effectiveness of immunotherapy in advanced NSCLC patients
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Transcriptome and experimental validation identify prognostic genes associated with lipotoxicity in thyroid carcinoma
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Multi-omics profiling reveals sphingolipid metabolism reprogramming of tumor-conditioned MDSCs in cervical cancer
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CYP19A1 promotes gastric cancer as part of a lipid metabolism-related gene signature related to the response of immunotherapy and prognosis
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A new era in melanoma immunotherapy: focus on DCs metabolic reprogramming
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Salivary metabolic profile landscape for gastric cancer screening: a metabolomic approach
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Tumor microenvironment dynamics in gastric cancer pathogenesis and therapeutic resistance
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Contradictory roles of lipid metabolism in immune response within the tumor microenvironment
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[Research Progress and New Immunotherapy Strategies of Tumor Microenvironment Metabolism].
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Reduced serum high-density lipoprotein cholesterol levels and aberrantly expressed cholesterol metabolism genes in colorectal cancer
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Development and validation of metabolic models for predicting survival and immune status of hepatocellular carcinoma patients
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Neural network analysis of some molecular parameters of the cervical epithelium for cervical cancer diagnostics
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Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more
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Metabolic crossroads: unravelling immune cell dynamics in gastrointestinal cancer drug resistance
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Characteristics, clinical significance, and cancer immune interactions of lipid metabolism in prostate cancer
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The pan-cancer landscape of crosstalk between chemokines and the tumor immune microenvironment
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The pan-cancer landscape of crosstalk between chemokinesand the tumor immune microenvironment
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ELOVL2, a novel and potential tumor antigen guided mRNA vaccine development for retroperitoneal liposarcoma
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Individualized Lipid Metabolism-Associated Six-Gene Signature for Prediction of Overall Survival, Immune Infiltration, Immunotherapy Response, and Potential Candidate Drugs in Lung Squamous Cell Carcinoma Patients: Development and Validation
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Drug Delivery Engineering Strategies Targeting CD4+/CD8+ T Cell Exhaustion to Improve the Tumor Immunosuppressive Microenvironment
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Development and Validation of a Prognostic Classifier Based on Lipid Metabolism-Related Genes for Breast Cancer
inferred← citeshttps://doi.org/10.2147/jir.s378212openalex-snapshot
Lipid Metabolic-Related Signature CYP19A1 is a Potential Biomarker for Prognosis and Immune Cell Infiltration in Gastric Cancer
inferred← citeshttps://doi.org/10.21873/invivo.13502openalex-snapshot
Serum CCDC25 Levels as a Potential Marker for Metabolic Syndrome
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Promising Therapeutic Approach in Pancreatic Cancer: Metabolism-Related Genes
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A Novel Risk Model Based on Lipid Metabolism-Associated Genes Predicts Prognosis and Indicates Immune Microenvironment in Breast Cancer
inferred← citeshttps://doi.org/10.3389/fcell.2023.1187989openalex-snapshot
Lipid metabolism and tumor immunotherapy
inferred← citeshttps://doi.org/10.3389/fendo.2024.1318416openalex-snapshot
Apolipoprotein A-I levels in the survival of patients with colorectal cancer: a retrospective study
inferred← citeshttps://doi.org/10.3389/fgene.2022.894736openalex-snapshot
A Fatty Acid Metabolism Signature Associated With Clinical Therapy in Clear Cell Renal Cell Carcinoma
inferred← citeshttps://doi.org/10.3389/fgene.2022.905508openalex-snapshot
Characterization of Fatty Acid Metabolism in Lung Adenocarcinoma
inferred← citeshttps://doi.org/10.3389/fgene.2022.989327openalex-snapshot
Identification of a novel lipid metabolism-related gene signature for predicting colorectal cancer survival
inferred← citeshttps://doi.org/10.3389/fimmu.2022.1016776openalex-snapshot
Combining all-trans retinoid acid treatment targeting myeloid-derived suppressive cells with cryo-thermal therapy enhances antitumor immunity in breast cancer
inferred← citeshttps://doi.org/10.3389/fimmu.2022.1033967openalex-snapshot
The role of Angiogenesis and remodeling (AR) associated signature for predicting prognosis and clinical outcome of immunotherapy in pan-cancer
inferred← citeshttps://doi.org/10.3389/fimmu.2022.831636openalex-snapshot
Cancer Metabolism: The Role of Immune Cells Epigenetic Alteration in Tumorigenesis, Progression, and Metastasis of Glioma
inferred← citeshttps://doi.org/10.3389/fimmu.2022.850093openalex-snapshot
The Interplay Between Inflammation and Stromal Components in Pancreatic Cancer
inferred← citeshttps://doi.org/10.3389/fimmu.2022.868669openalex-snapshot
Intracellular Lipid Accumulation Drives the Differentiation of Decidual Polymorphonuclear Myeloid-Derived Suppressor Cells via Arachidonic Acid Metabolism
inferred← citeshttps://doi.org/10.3389/fimmu.2022.937406openalex-snapshot
Targeting lipid metabolism reprogramming of immunocytes in response to the tumor microenvironment stressor: A potential approach for tumor therapy
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1176647openalex-snapshot
Role of ICAM1 in tumor immunity and prognosis of triple-negative breast cancer
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1209396openalex-snapshot
Insight of a lipid metabolism prognostic model to identify immune landscape and potential target for retroperitoneal liposarcoma
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A novel prognostic classification integrating lipid metabolism and immune co-related genes in acute myeloid leukemia
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The role of metabolic reprogramming in immune escape of triple-negative breast cancer
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1630279openalex-snapshot
Clinical application prospects of traditional Chinese medicine as adjuvant therapy for metabolic reprogramming in colorectal cancer
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Metabolic reprogramming in the post-metastatic tumor microenvironment: multi-omics insights into determinants of immunotherapy response
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Rewiring lipid metabolism to enhance immunotherapy efficacy in melanoma: a frontier in cancer treatment
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Unravelling the role of obesity and lipids during tumor progression
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Applying machine learning algorithms to develop a survival prediction model for lung adenocarcinoma based on genes related to fatty acid metabolism
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Oxidized Low-Density Lipoprotein as a Potential Target for Enhancing Immune Checkpoint Inhibitor Therapy in Microsatellite-Stable Colorectal Cancer
inferred← citeshttps://doi.org/10.3390/cancers14030510openalex-snapshot
Evolution and Targeting of Myeloid Suppressor Cells in Cancer: A Translational Perspective
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Redox Storm in the Tumor Microenvironment (ΤΜΕ): Multifaceted Redox Injury and Immunometabolic Reprogramming Induced by Immune Checkpoint Blockade in B16F10 Melanoma: An Ultrastructural Study of the Peritumoral Interface
inferred← citeshttps://doi.org/10.3390/ijms22042142openalex-snapshot
Metabolic Factors Affecting Tumor Immunogenicity: What Is Happening at the Cellular Level?
inferred← citeshttps://doi.org/10.3390/metabo12020194openalex-snapshot
The Potential of Metabolomics in Biomedical Applications
inferred← citeshttps://doi.org/10.3390/metabo12030213openalex-snapshot
Lipid Metabolism Interplay in CRC—An Update
inferred← citeshttps://doi.org/10.48550/arxiv.2011.05304openalex-snapshot
Label-free Raman spectroscopy and machine learning enables sensitive evaluation of differential response to immunotherapy
inferred← citeshttps://doi.org/10.6084/m9.figshare.24234199openalex-snapshot
Additional file 1 of CYP19A1 promotes gastric cancer as part of a lipid metabolism-related gene signature related to the response of immunotherapy and prognosis
inferred← citeshttps://doi.org/10.7150/thno.82920openalex-snapshot
The role of lipid metabolic reprogramming in tumor microenvironment
inferred← citeshttps://doi.org/10.7150/thno.85855openalex-snapshot
Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation
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