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Mechanisms of Male Reproductive Toxicity of Polybrominated Diphenyl Ethers

https://doi.org/10.3390/ijms232214229
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Association of In Utero Exposure to Polybrominated Diphenyl Ethers With the Risk of Hypospadias
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Spontaneous Lipid Peroxidation and Production of Hydrogen Peroxide and Superoxide in Human Spermatozoa Superoxide Dismutase as Major Enzyme Protectant Against Oxygen Toxicity
inferredcites →https://doi.org/10.1002/jat.1667openalex-snapshot
Delayed response in the rat frontal lobe transcriptome to perinatal exposure to the flame retardant BDE ‐47
inferredcites →https://doi.org/10.1002/jez.1402400116openalex-snapshot
Isolation and partial characterization of the plasma membrane from human spermatozoa
inferredcites →https://doi.org/10.1002/mnfr.200700104openalex-snapshot
Biotransformation of brominated flame retardants into potentially endocrine‐disrupting metabolites, with special attention to 2,2′,4,4′‐tetrabromodiphenyl ether (BDE‐47)
inferredcites →https://doi.org/10.1002/mrd.1080420311openalex-snapshot
Differential incorporation of fatty acids into and peroxidative loss of fatty acids from phospholipids of human spermatozoa
inferredcites →https://doi.org/10.1002/tox.20729openalex-snapshot
Developmental exposure to decabrominated diphenyl ether (BDE‐209): Effects on sperm oxidative stress and chromatin dna damage in mouse offspring
inferredcites →https://doi.org/10.1007/978-1-4939-7698-0_16openalex-snapshot
Regulation of Blood-Testis Barrier (BTB) Dynamics, Role of Actin-, and Microtubule-Based Cytoskeletons
inferredcites →https://doi.org/10.1007/bf01267351openalex-snapshot
4. Methoden der elektrischen Schmerzunterdr�ckung
inferredcites →https://doi.org/10.1007/s00128-008-9370-4openalex-snapshot
Polybrominated Diphenyl Ethers in Human Serum and Sperm Quality
inferredcites →https://doi.org/10.1007/s00128-012-0867-5openalex-snapshot
Adverse Effects of 2,2′,4,4′-Tetrabromodiphenyl Ether on Semen Quality and Spermatogenesis in Male Mice
inferredcites →https://doi.org/10.1007/s00204-015-1457-1openalex-snapshot
Human exposure to PBDE and critical evaluation of health hazards
inferredcites →https://doi.org/10.1007/s00204-018-2177-0openalex-snapshot
In utero and lactational exposure to BDE-47 promotes obesity development in mouse offspring fed a high-fat diet: impaired lipid metabolism and intestinal dysbiosis
inferredcites →https://doi.org/10.1007/s10815-015-0454-xopenalex-snapshot
Reactive Oxygen Species (ROS) in human semen: determination of a reference range
inferredcites →https://doi.org/10.1007/s11224-020-01664-zopenalex-snapshot
Endocrine-disrupting potential of polybrominated diphenyl ethers (PBDEs) on androgen receptor signaling: a structural insight
inferredcites →https://doi.org/10.1007/s11255-009-9644-8openalex-snapshot
Gonadal dysfunction and infertility in kidney transplant patients receiving sirolimus
inferredcites →https://doi.org/10.1007/s11356-008-0045-9openalex-snapshot
Oxidative transformation of polybrominated diphenyl ether congeners (PBDEs) and of hydroxylated PBDEs (OH-PBDEs)
inferredcites →https://doi.org/10.1007/s11356-022-20944-1openalex-snapshot
Hesperidin partly ameliorates the decabromodiphenyl ether-induced reproductive toxicity in pubertal mice
inferredcites →https://doi.org/10.1007/s11626-016-0061-xopenalex-snapshot
Mitochondrial membrane potential (MMP) regulates sperm motility
inferredcites →https://doi.org/10.1007/s12020-017-1303-8openalex-snapshot
Impact of thyroid disease on testicular function
inferredcites →https://doi.org/10.1007/s12601-015-0010-8openalex-snapshot
An overview of polybrominated diphenyl ethers (PBDEs) in the marine environment
inferredcites →https://doi.org/10.1016/0042-6822(92)90500-oopenalex-snapshot
Baculovirus-expressed glycoprotein E (gE) of herpes simplex virus type-1 (HSV-1) protects mice against lethal intraperitoneal and lethal ocular HSV-1 challenge
inferredcites →https://doi.org/10.1016/b978-0-12-407704-1.00006-3openalex-snapshot
Regulation of Blood–Testis Barrier (BTB) Dynamics during Spermatogenesis via the “Yin” and “Yang” Effects of Mammalian Target of Rapamycin Complex 1 (mTORC1) and mTORC2
inferredcites →https://doi.org/10.1016/b978-0-12-801238-3.11152-3openalex-snapshot
Polybrominated Biphenyls (PBBs)
inferredcites →https://doi.org/10.1016/j.bbalip.2009.03.001openalex-snapshot
Cholesterol transport in steroid biosynthesis: Role of protein–protein interactions and implications in disease states
inferredcites →https://doi.org/10.1016/j.chemosphere.2006.05.016openalex-snapshot
Bioavailability and mass balance studies of a commercial pentabromodiphenyl ether mixture in male Sprague–Dawley rats
inferredcites →https://doi.org/10.1016/j.chemosphere.2008.01.032openalex-snapshot
Effects of fifteen PBDE metabolites, DE71, DE79 and TBBPA on steroidogenesis in the H295R cell line
inferredcites →https://doi.org/10.1016/j.chemosphere.2008.10.064openalex-snapshot
Congener specific distributions of polybrominated diphenyl ethers (PBDEs) in sediment and mussel (Mytilus edulis) of the Bo Sea, China
inferredcites →https://doi.org/10.1016/j.chemosphere.2010.04.055openalex-snapshot
Hypospadias and halogenated organic pollutant levels in maternal mid-pregnancy serum samples
inferredcites →https://doi.org/10.1016/j.chemosphere.2012.11.001openalex-snapshot
Polychlorinated biphenyls (PCBs) and Polybrominated Diphenyl ethers (PBDEs) in three fish species from an estuary in the southeastern coast of Brazil
inferredcites →https://doi.org/10.1016/j.chemosphere.2014.11.015openalex-snapshot
Persistent organic pollutants and semen quality: The LIFE Study
inferredcites →https://doi.org/10.1016/j.chemosphere.2018.01.150openalex-snapshot
Associations between PBDEs exposure from house dust and human semen quality at an e-waste areas in South China–A pilot study
inferredcites →https://doi.org/10.1016/j.chemosphere.2018.06.108openalex-snapshot
Association of polybrominated diphenyl ethers in two fat compartments with increased risk of insulin resistance in obese individuals
inferredcites →https://doi.org/10.1016/j.chemosphere.2020.125905openalex-snapshot
Serum elimination half-lives adjusted for ongoing exposure of tri-to hexabrominated diphenyl ethers: Determined in persons moving from North America to Australia
inferredcites →https://doi.org/10.1016/j.ecoenv.2020.111783openalex-snapshot
Decabromodiphenyl ether (BDE-209) exposure to lactating mice perturbs steroidogenesis and spermatogenesis in adult male offspring
inferredcites →https://doi.org/10.1016/j.envint.2015.12.002openalex-snapshot
Concentrations of polybrominated diphenyl ethers (PBDEs) and 2,4,6-tribromophenol in human placental tissues
inferredcites →https://doi.org/10.1016/j.envint.2018.02.044openalex-snapshot
Association between persistent endocrine-disrupting chemicals (PBDEs, OH-PBDEs, PCBs, and PFASs) and biomarkers of inflammation and cellular aging during pregnancy and postpartum
inferredcites →https://doi.org/10.1016/j.envint.2018.04.012openalex-snapshot
Exposure to polybrominated diphenyl ethers and phthalates in healthy men living in the greater Montreal area: A study of hormonal balance and semen quality
inferredcites →https://doi.org/10.1016/j.envint.2018.11.040openalex-snapshot
Dietary exposure to brominated flame retardants and risk of type 2 diabetes in the French E3N cohort
inferredcites →https://doi.org/10.1016/j.envpol.2013.07.005openalex-snapshot
Placental IGF-1 and IGFBP-3 expression correlate with umbilical cord blood PAH and PBDE levels from prenatal exposure to electronic waste
inferredcites →https://doi.org/10.1016/j.envpol.2019.113097openalex-snapshot
BDE-209 induces male reproductive toxicity via cell cycle arrest and apoptosis mediated by DNA damage response signaling pathways
inferredcites →https://doi.org/10.1016/j.envpol.2020.115773openalex-snapshot
Impaired sperm quantity and motility in adult rats following gestational and lactational exposure to environmentally relevant levels of PBDE-47: A potential role of thyroid hormones disruption
inferredcites →https://doi.org/10.1016/j.envres.2016.09.002openalex-snapshot
Association between serum concentrations of persistent organic pollutants and gestational diabetes mellitus in primiparous women
inferredcites →https://doi.org/10.1016/j.etap.2016.08.011openalex-snapshot
2,2′,4,4′-Tetrabromodiphenyl ether injures cell viability and mitochondrial function of mouse spermatocytes by decreasing mitochondrial proteins Atp5b and Uqcrc1
inferredcites →https://doi.org/10.1016/j.etap.2017.08.030openalex-snapshot
BDE-47 and BDE-85 stimulate insulin secretion in INS-1 832/13 pancreatic β-cells through the thyroid receptor and Akt
inferredcites →https://doi.org/10.1016/j.fct.2005.12.010openalex-snapshot
Flutamide depresses expression of cortactin in the ectoplasmic specialization between the Sertoli cells and spermatids in the mouse testis
inferredcites →https://doi.org/10.1016/j.fct.2010.05.048openalex-snapshot
Effects of BDE-99 on hormone homeostasis and biochemical parameters in adult male rats
inferredcites →https://doi.org/10.1016/j.fertnstert.2004.05.106openalex-snapshot
Characterization of oxidative stress status by evaluation of reactive oxygen species levels in whole semen and isolated spermatozoa
inferredcites →https://doi.org/10.1016/j.fertnstert.2004.11.022openalex-snapshot
Effect of reactive oxygen species produced by spermatozoa and leukocytes on sperm functions in non-leukocytospermic patients
inferredcites →https://doi.org/10.1016/j.ijheh.2011.10.004openalex-snapshot
Cord blood levels of thyroid hormones and IGF-1 weakly correlate with breast milk levels of PBDEs in Taiwan
inferredcites →https://doi.org/10.1016/j.ijheh.2016.11.001openalex-snapshot
In utero and childhood DDT, DDE, PBDE and PCBs exposure and sex hormones in adolescent boys: The CHAMACOS study
inferredcites →https://doi.org/10.1016/j.ijheh.2019.113445openalex-snapshot
Multi-exposures to suspected endocrine disruptors in electronic waste recycling workers: Associations with thyroid and reproductive hormones
inferredcites →https://doi.org/10.1016/j.jhazmat.2021.127547openalex-snapshot
Prenatal exposure to environmentally relevant levels of PBDE-99 leads to testicular dysgenesis with steroidogenesis disorders
inferredcites →https://doi.org/10.1016/j.jpurol.2019.05.023openalex-snapshot
Fetal exposure to polybrominated diphenyl ethers and the risk of hypospadias: focus on the congeners involved
inferredcites →https://doi.org/10.1016/j.jri.2017.12.002openalex-snapshot
Effect of polybrominated diphenyl ether congeners on placental cytokine production
inferredcites →https://doi.org/10.1016/j.marpolbul.2011.04.019openalex-snapshot
In vitro profiling of endocrine disrupting potency of 2,2′,4,4′-tetrabromodiphenyl ether (BDE47) and related hydroxylated analogs (HO-PBDEs)
inferredcites →https://doi.org/10.1016/j.marpolbul.2011.08.037openalex-snapshot
Endocrine effects of methoxylated brominated diphenyl ethers in three in vitro models
inferredcites →https://doi.org/10.1016/j.mce.2013.04.014openalex-snapshot
Steroid hormone synthesis in mitochondria
inferredcites →https://doi.org/10.1016/j.mito.2020.06.003openalex-snapshot
Mitochondria, spermatogenesis, and male infertility – An update
inferredcites →https://doi.org/10.1016/j.placenta.2012.06.005openalex-snapshot
Polybrominated diphenyl ethers enhance the production of proinflammatory cytokines by the placenta
inferredcites →https://doi.org/10.1016/j.reprotox.2004.02.011openalex-snapshot
Flutamide induces ultrastructural changes in spermatids and the ectoplasmic specialization between the Sertoli cell and spermatids in mouse testes
inferredcites →https://doi.org/10.1016/j.reprotox.2008.12.002openalex-snapshot
Alteration of testicular steroidogenesis and histopathology of reproductive system in male rats treated with triclosan
inferredcites →https://doi.org/10.1016/j.reprotox.2011.02.005openalex-snapshot
Polybrominated diphenyl ethers and sperm quality
inferredcites →https://doi.org/10.1016/j.reprotox.2013.10.002openalex-snapshot
Exposure to polybrominated diphenyl ethers and male reproductive function in Greenland, Poland and Ukraine
inferredcites →https://doi.org/10.1016/j.reprotox.2016.04.009openalex-snapshot
Polybrominated diphenyl ether exposure and reproductive hormones in North American men
inferredcites →https://doi.org/10.1016/j.reprotox.2017.10.009openalex-snapshot
Perinatal exposure to low dose 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) alters sperm DNA methylation in adult rats
inferredcites →https://doi.org/10.1016/j.scitotenv.2009.01.030openalex-snapshot
Polybrominated diphenyl ether (PBDE) concentrations in house dust are related to hormone levels in men
inferredcites →https://doi.org/10.1016/j.scitotenv.2012.12.017openalex-snapshot
Associations between brominated flame retardants in house dust and hormone levels in men
inferredcites →https://doi.org/10.1016/j.scitotenv.2019.03.319openalex-snapshot
Polybrominated diphenyl ethers in human serum, semen and indoor dust: Effects on hormones balance and semen quality
inferredcites →https://doi.org/10.1016/j.scitotenv.2019.133902openalex-snapshot
Polybrominated diphenyl ethers in the environment and human external and internal exposure in China: A review
inferredcites →https://doi.org/10.1016/j.scitotenv.2020.137419openalex-snapshot
Toxicity of polybrominated diphenyl ethers (PBDEs) on rodent male reproductive system: A systematic review and meta-analysis of randomized control studies
inferredcites →https://doi.org/10.1016/j.scitotenv.2020.142936openalex-snapshot
Decabromodiphenyl ether disturbs hepatic glycolipid metabolism by regulating the PI3K/AKT/GLUT4 and mTOR/PPARγ/RXRα pathway in mice and L02 cells
inferredcites →https://doi.org/10.1016/j.taap.2005.05.010openalex-snapshot
In vivo and in vitro anti-androgenic effects of DE-71, a commercial polybrominated diphenyl ether (PBDE) mixture
inferredcites →https://doi.org/10.1016/j.taap.2006.02.008openalex-snapshot
Polybrominated diphenyl ether (PBDE)-induced alterations in vitamin A and thyroid hormone concentrations in the rat during lactation and early postnatal development
inferredcites →https://doi.org/10.1016/j.taap.2008.06.014openalex-snapshot
Biosensor discovery of thyroxine transport disrupting chemicals
inferredcites →https://doi.org/10.1016/j.taap.2017.03.010openalex-snapshot
High-fat diet aggravates 2,2′,4,4′-tetrabromodiphenyl ether-inhibited testosterone production via DAX-1 in Leydig cells in rats
inferredcites →https://doi.org/10.1016/j.tox.2006.04.003openalex-snapshot
Postnatal exposure of the male mouse to 2,2′,3,3′,4,4′,5,5′,6,6′-decabrominated diphenyl ether: Decreased epididymal sperm functions without alterations in DNA content and histology in testis
inferredcites →https://doi.org/10.1016/j.tox.2009.03.018openalex-snapshot
Perinatal exposure to low-dose 2,2′,4,4′-tetrabromodiphenyl ether affects growth in rat offspring: What is the role of IGF-1?
inferredcites →https://doi.org/10.1016/j.tox.2010.08.012openalex-snapshot
Structure-based investigation on the binding interaction of hydroxylated polybrominated diphenyl ethers with thyroxine transport proteins
inferredcites →https://doi.org/10.1016/j.tox.2013.04.001openalex-snapshot
Structure-dependent activities of hydroxylated polybrominated diphenyl ethers on human estrogen receptor
inferredcites →https://doi.org/10.1016/j.tox.2014.01.005openalex-snapshot
Toxicity assessment of air-delivered particle-bound polybrominated diphenyl ethers
inferredcites →https://doi.org/10.1016/j.tox.2017.05.016openalex-snapshot
Maternal exposure to polybrominated diphenyl ether (BDE-209) during lactation affects germ cell survival with altered testicular glucose homeostasis and oxidative status through down-regulation of Cx43 and p27Kip1 in prepubertal mice offspring
inferredcites →https://doi.org/10.1016/j.tox.2017.07.006openalex-snapshot
Perinatal exposure to 2,2′,4′4′ −Tetrabromodiphenyl ether induces testicular toxicity in adult rats
inferredcites →https://doi.org/10.1016/j.toxlet.2007.12.001openalex-snapshot
Effects of 20 PBDE metabolites on steroidogenesis in the H295R cell line
inferredcites →https://doi.org/10.1016/j.toxlet.2008.03.003openalex-snapshot
A 28-day oral dose toxicity study in Wistar rats enhanced to detect endocrine effects of decabromodiphenyl ether (decaBDE)
inferredcites →https://doi.org/10.1016/j.toxlet.2011.06.011openalex-snapshot
Effect of brominated flame retardant BDE-47 on androgen production of adult rat Leydig cells
inferredcites →https://doi.org/10.1016/j.toxlet.2021.02.006openalex-snapshot
Low dose of fire retardant, 2,2’,4,4’-tetrabromodiphenyl ether (BDE47), stimulates the proliferation and differentiation of progenitor Leydig cells of male rats during prepuberty
inferredcites →https://doi.org/10.1016/j.wasman.2021.05.038openalex-snapshot
Evaluation of polybrominated diphenyl ether (PBDE) flame retardants from various materials in professional seating furnishing wastes from French flows
inferredcites →https://doi.org/10.1016/j.ygcen.2015.11.009openalex-snapshot
Effect of polybrominated diphenyl ether (BDE-209) on testicular steroidogenesis and spermatogenesis through altered thyroid status in adult mice
inferredcites →https://doi.org/10.1016/s0015-0282(16)43999-3openalex-snapshot
Peroxidative Breakdown of Phospholipids in Human Spermatozoa, Spermicidal Properties of Fatty Acid Peroxides, and Protective Action of Seminal Plasma
inferredcites →https://doi.org/10.1016/s0015-0282(16)56895-2openalex-snapshot
Reactive oxygen species released by activated neutrophils, but not by deficient spermatozoa, are sufficient to affect normal sperm motility
inferredcites →https://doi.org/10.1021/acs.chemrestox.5b00072openalex-snapshot
Disruption of Type 2 Iodothyronine Deiodinase Activity in Cultured Human Glial Cells by Polybrominated Diphenyl Ethers
inferredcites →https://doi.org/10.1021/acs.est.7b00565openalex-snapshot
Temporal Evaluation of Polybrominated Diphenyl Ether (PBDE) Serum Levels in Middle-Aged and Older California Women, 2011–2015
inferredcites →https://doi.org/10.1021/acs.est.8b01540openalex-snapshot
Human Sex Hormone Disrupting Effects of New Flame Retardants and Their Interactions with Polychlorinated Biphenyls, Polybrominated Diphenyl Ethers, a Case Study in South China
inferredcites →https://doi.org/10.1021/acs.est.8b07032openalex-snapshot
Global Historical Stocks and Emissions of PBDEs
inferredcites →https://doi.org/10.1021/es050399xopenalex-snapshot
Polybrominated Diphenyl Ethers and Polychlorinated Biphenyls in Human Adipose Tissue from New York
inferredcites →https://doi.org/10.1021/es060836nopenalex-snapshot
Xenoendocrine Pollutants May Reduce Size of Sexual Organs in East Greenland Polar Bears (Ursus maritimus)
inferredcites →https://doi.org/10.1021/es1035046openalex-snapshot
Total Consumer Exposure to Polybrominated Diphenyl Ethers in North America and Europe
inferredcites →https://doi.org/10.1021/es2046074openalex-snapshot
Assessment of the Binding of Hydroxylated Polybrominated Diphenyl Ethers to Thyroid Hormone Transport Proteins Using a Site-Specific Fluorescence Probe
inferredcites →https://doi.org/10.1021/tx100231nopenalex-snapshot
Endocrine Disrupting Chemicals Targeting Estrogen Receptor Signaling: Identification and Mechanisms of Action
inferredcites →https://doi.org/10.1038/aja.2011.40openalex-snapshot
The effect of environmental contaminants on testicular function
inferredcites →https://doi.org/10.1038/ncb2763openalex-snapshot
Signal integration by mTORC1 coordinates nutrient input with biosynthetic output
inferredcites →https://doi.org/10.1038/nrm3025openalex-snapshot
mTOR: from growth signal integration to cancer, diabetes and ageing
inferredcites →https://doi.org/10.1038/oby.2007.351openalex-snapshot
Polybrominated Diphenyl Ethers as Endocrine Disruptors of Adipocyte Metabolism
inferredcites →https://doi.org/10.1038/s41467-019-09234-6openalex-snapshot
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
inferredcites →https://doi.org/10.1038/s41598-018-20443-9openalex-snapshot
Associations between serum polybrominated diphenyl ethers and thyroid hormones in a cross sectional study of a remote Alaska Native population
inferredcites →https://doi.org/10.1038/s41598-018-23484-2openalex-snapshot
Metabolomics coupled with pathway analysis characterizes metabolic changes in response to BDE-3 induced reproductive toxicity in mice
inferredcites →https://doi.org/10.1038/s41598-020-74853-9openalex-snapshot
Maternal transfer of environmentally relevant polybrominated diphenyl ethers (PBDEs) produces a diabetic phenotype and disrupts glucoregulatory hormones and hepatic endocannabinoids in adult mouse female offspring
inferredcites →https://doi.org/10.1038/s41598-021-86805-yopenalex-snapshot
Environmental chemicals in dog testes reflect their geographical source and may be associated with altered pathology
inferredcites →https://doi.org/10.1038/srep32916openalex-snapshot
Chemical exposure-response relationship between air pollutants and reactive oxygen species in the human respiratory tract
inferredcites →https://doi.org/10.1042/bj20040178openalex-snapshot
Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase
inferredcites →https://doi.org/10.1046/j.1365-2605.1999.00145.xopenalex-snapshot
Reactive oxygen species influence the acrosome reaction but not acrosin activity in human spermatozoa
inferredcites →https://doi.org/10.1074/jbc.m803867200openalex-snapshot
Cross-talk between G Protein-coupled and Epidermal Growth Factor Receptors Regulates Gonadotropin-mediated Steroidogenesis in Leydig Cells
inferredcites →https://doi.org/10.1080/00498250500485107openalex-snapshot
Metabolism and disposition of 2,2′,4,4′- tetrabromodiphenyl ether following administration of single or multiple doses to rats and mice
inferredcites →https://doi.org/10.1080/10934529.2011.602937openalex-snapshot
Cytotoxic effects and oxidative stress response of six PBDE metabolites on human L02 cells
inferredcites →https://doi.org/10.1089/ars.2010.3186openalex-snapshot
Redox Regulation of Human Sperm Function: From the Physiological Control of Sperm Capacitation to the Etiology of Infertility and DNA Damage in the Germ Line
inferredcites →https://doi.org/10.1089/ars.2011.4085openalex-snapshot
Mitochondrial Regulation of Cell Cycle and Proliferation
inferredcites →https://doi.org/10.1093/humrep/10.suppl_1.15openalex-snapshot
Impact of reactive oxygen species on spermatozoa: a balancing act between beneficial and detrimental effects
inferredcites →https://doi.org/10.1093/humrep/der165openalex-snapshot
Effects of polybrominated diphenyl ethers on steroidogenesis in rat Leydig cells
inferredcites →https://doi.org/10.1093/humrep/der426openalex-snapshot
Influence of prenatal organohalogen levels on infant male sexual development: sex hormone levels, testes volume and penile length
inferredcites →https://doi.org/10.1093/toxsci/kfh029openalex-snapshot
Assessment of DE-71, a Commercial Polybrominated Diphenyl Ether (PBDE) Mixture, in the EDSP Male and Female Pubertal Protocols
inferredcites →https://doi.org/10.1093/toxsci/kfj187openalex-snapshot
In Vitro Profiling of the Endocrine-Disrupting Potency of Brominated Flame Retardants
inferredcites →https://doi.org/10.1093/toxsci/kfq105openalex-snapshot
Developmental Exposure to a Commercial PBDE Mixture, DE-71: Neurobehavioral, Hormonal, and Reproductive Effects
inferredcites →https://doi.org/10.1093/toxsci/kfy230openalex-snapshot
Genomic Profiling of BDE-47 Effects on Human Placental Cytotrophoblasts
inferredcites →https://doi.org/10.1093/toxsci/kfz147openalex-snapshot
Gestational and Lactational Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants Downregulates Junctional Proteins, Thyroid Hormone Receptor α1 Expression, and the Proliferation-Apoptosis Balance in Mammary Glands Post Puberty
inferredcites →https://doi.org/10.1095/biolreprod.110.087460openalex-snapshot
ATP Synthesis, Mitochondrial Function, and Steroid Biosynthesis in Rodent Primary and Tumor Leydig Cells1
inferredcites →https://doi.org/10.1096/fj.12-212977openalex-snapshot
Rictor/mTORC2 regulates blood‐testis barrier dynamics via its effects on gap junction communications and actin filament network
inferredcites →https://doi.org/10.1097/00007890-199903150-00013openalex-snapshot
LONG-TERM FOLLOW-UP OF LIVING KIDNEY DONORS: QUALITY OF LIFE AFTER DONATION1
inferredcites →https://doi.org/10.1097/01.ju.0000053866.68623.daopenalex-snapshot
Increasing Incidence of Testicular Cancer Worldwide: A Review
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Obesity and male infertility
inferredcites →https://doi.org/10.1111/and.13617openalex-snapshot
Obesity and male infertility: Mechanisms and management
inferredcites →https://doi.org/10.1111/andr.12918openalex-snapshot
Somatotropic‐Testicular Axis: A crosstalk between GH/IGF‐I and gonadal hormones during development, transition, and adult age
inferredcites →https://doi.org/10.1111/bcpt.12598openalex-snapshot
Evaluation of Polybrominated Diphenyl Ether Toxicity on HepG2 Cells – Hexabrominated Congener ( BDE ‐154) Is Less Toxic than Tetrabrominated Congener ( BDE ‐47)
inferredcites →https://doi.org/10.1111/j.1439-0272.2011.01252.xopenalex-snapshot
Effects of reactive oxygen species from activated leucocytes on human sperm motility, viability and morphology
inferredcites →https://doi.org/10.1111/j.1600-6143.2007.01929.xopenalex-snapshot
Sirolimus‐Associated Infertility: Case Report and Literature Review of Possible Mechanisms
inferredcites →https://doi.org/10.1111/rda.13665openalex-snapshot
Effects of bisphenol A, diethylhexyl phthalate and pentabrominated diphenyl ether 99 on steroid synthesis in cultured bovine luteal cells
inferredcites →https://doi.org/10.1124/pr.110.002790openalex-snapshot
The Blood-Testis Barrier and Its Implications for Male Contraception
inferredcites →https://doi.org/10.1126/science.1260419openalex-snapshot
Tissue-based map of the human proteome
inferredcites →https://doi.org/10.1128/mcb.00217-10openalex-snapshot
Cyclic AMP Controls mTOR through Regulation of the Dynamic Interaction between Rheb and Phosphodiesterase 4D
inferredcites →https://doi.org/10.1155/2012/645460openalex-snapshot
Drug-Induced Oxidative Stress and Toxicity
inferredcites →https://doi.org/10.1155/2014/234014openalex-snapshot
Growth Hormone and Reproduction: A Review of Endocrine and Autocrine/Paracrine Interactions
inferredcites →https://doi.org/10.1155/2014/635979openalex-snapshot
The Dynamic of the Apical Ectoplasmic Specialization between Spermatids and Sertoli Cells: The Case of the Small GTPase Rap1
inferredcites →https://doi.org/10.1155/2017/8416763openalex-snapshot
Oxidative Stress: Harms and Benefits for Human Health
inferredcites →https://doi.org/10.1159/000155651openalex-snapshot
Perinatal Exposure to Low-Dose BDE-47, an Emergent Environmental Contaminant, Causes Hyperactivity in Rat Offspring
inferredcites →https://doi.org/10.1159/000209316openalex-snapshot
Thyroid Disruption by Low-Dose BDE-47 in Prenatally Exposed Lambs
inferredcites →https://doi.org/10.1159/000373980openalex-snapshot
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
inferredcites →https://doi.org/10.1172/jci83532openalex-snapshot
Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning
inferredcites →https://doi.org/10.1177/039139889101401001openalex-snapshot
Artificial Organs - An Overview
inferredcites →https://doi.org/10.1186/1476-069x-7-58openalex-snapshot
Facing the Challenge of Data Transfer from Animal Models to Humans: the Case of Persistent Organohalogens
inferredcites →https://doi.org/10.1186/1477-7827-2-12openalex-snapshot
Reactive oxygen species and sperm cells
inferredcites →https://doi.org/10.1186/1477-7827-7-118openalex-snapshot
The measurement of reactive oxygen species in human neat semen and in suspended spermatozoa: a comparison
inferredcites →https://doi.org/10.1186/s12301-020-00061-6openalex-snapshot
Impact of oxidative stress on semen parameters in normozoospermic infertile men: a case–control study
inferredcites →https://doi.org/10.1186/s12940-016-0141-0openalex-snapshot
PBDE flame retardants, thyroid disease, and menopausal status in U.S. women
inferredcites →https://doi.org/10.1186/s12958-018-0341-2openalex-snapshot
The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells
inferredcites →https://doi.org/10.1203/pdr.0b013e3181a9eafbopenalex-snapshot
Oxygen Toxicity and Reactive Oxygen Species: The Devil Is in the Details
inferredcites →https://doi.org/10.1210/en.2012-1665openalex-snapshot
rpS6 Regulates Blood-Testis Barrier Dynamics By Affecting F-Actin Organization and Protein Recruitment
inferredcites →https://doi.org/10.1210/en.2014-1154openalex-snapshot
Polybrominated Diphenyl Ether (DE-71) Interferes With Thyroid Hormone Action Independent of Effects on Circulating Levels of Thyroid Hormone in Male Rats
inferredcites →https://doi.org/10.1210/endo.141.5.7468openalex-snapshot
Thyroid Hormone Down-Regulates Neural Cell Adhesion Molecule Expression and Affects Attachment of Gonocytes in Sertoli Cell-Gonocyte Cocultures1
inferredcites →https://doi.org/10.1210/er.2009-0041openalex-snapshot
Thyroid Function and Human Reproductive Health
inferredcites →https://doi.org/10.1210/er.2010-0013openalex-snapshot
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
inferredcites →https://doi.org/10.1210/jc.87.3.1142openalex-snapshot
Potent Inhibition of Estrogen Sulfotransferase by Hydroxylated Metabolites of Polyhalogenated Aromatic Hydrocarbons Reveals Alternative Mechanism for Estrogenic Activity of Endocrine Disrupters
inferredcites →https://doi.org/10.1210/js.2016-1011openalex-snapshot
Developmental Exposure to 2,2′,4,4′–Tetrabromodiphenyl Ether Induces Long-Lasting Changes in Liver Metabolism in Male Mice
inferredcites →https://doi.org/10.1242/jcs.099234openalex-snapshot
Mitochondria and cell signalling
inferredcites →https://doi.org/10.1242/jcs.125773openalex-snapshot
Regulation of mTORC1 and its impact on gene expression at a glance
inferredcites →https://doi.org/10.1248/jhs.54.607openalex-snapshot
Affinity for Thyroid Hormone and Estrogen Receptors of Hydroxylated Polybrominated Diphenyl Ethers
inferredcites →https://doi.org/10.1289/ehp.01109399openalex-snapshot
In vitro estrogenicity of polybrominated diphenyl ethers, hydroxylated PDBEs, and polybrominated bisphenol A compounds.
inferredcites →https://doi.org/10.1289/ehp.0900753openalex-snapshot
Nuclear Hormone Receptor Activity of Polybrominated Diphenyl Ethers and Their Hydroxylated and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells
inferredcites →https://doi.org/10.1289/ehp.0901031openalex-snapshot
Global Gene Expression Analysis in the Livers of Rat Offspring Perinatally Exposed to Low Doses of 2,2′,4,4′-Tetrabromodiphenyl Ether
inferredcites →https://doi.org/10.1289/ehp.11343openalex-snapshot
Hydroxylated Metabolites of the Polybrominated Diphenyl Ether Mixture DE-71 Are Weak Estrogen Receptor-α Ligands
inferredcites →https://doi.org/10.1289/ehp.11570openalex-snapshot
Dietary Exposure to 2,2′,4,4′-Tetrabromodiphenyl Ether (PBDE-47) Alters Thyroid Status and Thyroid Hormone–Regulated Gene Transcription in the Pituitary and Brain
inferredcites →https://doi.org/10.1289/ehp.11707openalex-snapshot
Hormone Disruption by PBDEs in Adult Male Sport Fish Consumers
inferredcites →https://doi.org/10.1289/ehp.7421openalex-snapshot
Developmental Exposure to Low-Dose PBDE-99: Effects on Male Fertility and Neurobehavior in Rat Offspring
inferredcites →https://doi.org/10.1289/ehp.9924openalex-snapshot
Flame Retardants in Placenta and Breast Milk and Cryptorchidism in Newborn Boys
inferredcites →https://doi.org/10.1289/ehp2387openalex-snapshot
Hydroxylated Polybrominated Biphenyl Ethers Exert Estrogenic Effects via Non-Genomic G Protein–Coupled Estrogen Receptor Mediated Pathways
inferredcites →https://doi.org/10.1289/ehp3958openalex-snapshot
Erratum: “Hydroxylated Polybrominated Biphenyl Ethers Exert Estrogenic Effects via Nongenomic G Protein–Coupled Estrogen Receptor Mediated Pathways”
inferredcites →https://doi.org/10.1289/ehp522openalex-snapshot
A Case–Control Study of Maternal Polybrominated Diphenyl Ether (PBDE) Exposure and Cryptorchidism in Canadian Populations
inferredcites →https://doi.org/10.1371/journal.pone.0066301openalex-snapshot
Cytochrome P450 3A1 Mediates 2,2′,4,4′-Tetrabromodiphenyl Ether-Induced Reduction of Spermatogenesis in Adult Rats
inferredcites →https://doi.org/10.1371/journal.pone.0084606openalex-snapshot
Disrupting Immune Regulation Incurs Transient Costs in Male Reproductive Function
inferredcites →https://doi.org/10.1371/journal.pone.0114487openalex-snapshot
Early Postnatal Exposure to a Low Dose of Decabromodiphenyl Ether Affects Expression of Androgen and Thyroid Hormone Receptor-Alpha and Its Splicing Variants in Mouse Sertoli Cells
inferredcites →https://doi.org/10.1371/journal.pone.0126989openalex-snapshot
The Correlation between Polybrominated Diphenyl Ethers (PBDEs) and Thyroid Hormones in the General Population: A Meta-Analysis
inferredcites →https://doi.org/10.1371/journal.pone.0224644openalex-snapshot
Transcriptomic profiling of PBDE-exposed HepaRG cells unveils critical lncRNA- PCG pairs involved in intermediary metabolism
inferredcites →https://doi.org/10.14670/hh-11-753openalex-snapshot
Mammalian target of rapamycin complex (mTOR) pathway modulates blood-testis barrier (BTB) function through F-actin organization and gap junction.
inferredcites →https://doi.org/10.1530/jrf.0.0350265openalex-snapshot
THE PHOSPHOLIPID COMPOSITION OF HUMAN SPERMATOZOA AND SEMINAL PLASMA
inferredcites →https://doi.org/10.1530/jrf.0.0810459openalex-snapshot
Cellular basis of defective sperm function and its association with the genesis of reactive oxygen species by human spermatozoa
inferredcites →https://doi.org/10.1530/rep-14-0240openalex-snapshot
Oxidative stress impairs function and increases redox protein modifications in human spermatozoa
inferredcites →https://doi.org/10.20455/ros.2016.803openalex-snapshot
Defining ROS in Biology and Medicine
inferredcites →https://doi.org/10.20944/preprints202109.0066.v1openalex-snapshot
In Utero Exposure to Persistent Organic Pollutants and Childhood Lipid Levels
inferredcites →https://doi.org/10.21037/apm-21-1697openalex-snapshot
The potential association of polybrominated diphenyl ether concentrations in serum to thyroid function in patients with abnormal thyroids: a pilot study
inferredcites →https://doi.org/10.2131/jts.37.987openalex-snapshot
Postnatal exposure to low-dose decabromodiphenyl ether adversely affects mouse testes by increasing thyrosine phosphorylation level of cortactin
inferredcites →https://doi.org/10.21873/invivo.12531openalex-snapshot
Diabetes Mellitus Causes Male Reproductive Dysfunction: A Review of the Evidence and Mechanisms
inferredcites →https://doi.org/10.22074/ijfs.2016.4911openalex-snapshot
Thyroxin Is Useful to Improve Sperm Motility.
inferredcites →https://doi.org/10.2217/epi-2019-0315openalex-snapshot
Rat Liver Epigenome Programing by Perinatal Exposure to 2,2′,4′4′-Tetrabromodiphenyl Ether
inferredcites →https://doi.org/10.2217/epi-2020-0404openalex-snapshot
Aging-Induced Changes in Sperm DNA Methylation are Modified by Low Dose of Perinatal Flame Retardants
inferredcites →https://doi.org/10.3109/19396368.2013.821540openalex-snapshot
The relationship between seminal leukocytes, oxidative status in the ejaculate, and apoptotic markers in human spermatozoa
inferredcites →https://doi.org/10.3109/xen.28.2.199openalex-snapshot
Metabolism of 2,2, 4,4-tetrabromodiphenyl ether in rat and mouse
inferredcites →https://doi.org/10.3121/cmr.1.4.281openalex-snapshot
Polybrominated Diphenyl Ethers (PBDEs): New Pollutants-Old Diseases
inferredcites →https://doi.org/10.3389/fendo.2018.00548openalex-snapshot
Developmental Exposure to 2,2′,4,4′-Tetrabromodiphenyl Ether Permanently Alters Blood-Liver Balance of Lipids in Male Mice
inferredcites →https://doi.org/10.3390/biom11060821openalex-snapshot
Integrated Proteomic and Metabolomic Analysis of the Testes Characterizes BDE-47-Induced Reproductive Toxicity in Mice
inferredcites →https://doi.org/10.3390/ijerph16040588openalex-snapshot
Sub-lethal Doses of Polybrominated Diphenyl Ethers, in Vitro, Promote Oxidative Stress and Modulate Molecular Markers Related to Cell Cycle, Antioxidant Balance and Cellular Energy Management
inferredcites →https://doi.org/10.3390/ijms21218252openalex-snapshot
Aging Induces Profound Changes in sncRNA in Rat Sperm and These Changes Are Modified by Perinatal Exposure to Environmental Flame Retardant
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p-phenoxyphenol impaired male fertility by disrupting the testicular function and local microenvironment
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Developmental exposures to common environmental pollutants result in long-term Reprogramming of hypothalamic-pituitary axis in mice
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Adverse outcome pathways of PBDEs inducing male reproductive toxicity
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Associations of environmental chemical exposures measured in personal silicone wristbands with sociodemographic factors, COVID-19 restrictions, and child respiratory health
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Fetal exposure to persistent organic pollutants and childhood autism risk
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Epigenetic transgenerational effects of prenatal exposure to 2,2′,4,4′-tetrabromodiphenyl ether on sperm function and DNA methylation in rat offspring
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Chemical tailoring of silicon carbide nanotubes as sensors for polybrominated diphenyl ether (PBDE): A computational study of bismuth mono-doping and co-doping with chalcogenides
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An in-depth and critical look at microextraction techniques for the sample pretreatment of polybrominated diphenyl ethers
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Melatonin improves synaptic morphological plasticity of adolescent male rats after perinatal BDE-209 exposure via SIRT1-mediated LIMK1 and CREB signaling
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Dysregulation of mRNA expression by hsa-miR-186 overexpression in arsenic-induced skin carcinogenesis
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Advanced understanding of the polybrominated diphenyl ethers (PBDEs): Insights from total environment to intoxication
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Classification Pretraining Enhances Performance of Target-Based Affinity Prediction for Reproductive Toxicity Assessment
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Molecular Mechanisms Involved in Sperm Development, Maturation, and Fertilization
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Assessment of Per- and Poly-Fluoroalkyl Substances (PFAS) and Polybrominated Diphenyl Ethers (PBDEs) in Surface Waters Used for Urban Water Supply in Brazil
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