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Exploring Pharmacological Treatments for Chronic Idiopathic Constipation in Adults: A Look Back to the Future

https://doi.org/10.3390/jcm12041702

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Effects of trimebutine on colonic function in patients with chronic idiopathic constipation

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Misoprostol is effective treatment for patients with severe chronic constipation

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Colchicine is effective for short-term treatment of slow transit constipation: a double-blind placebo-controlled clinical trial

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Pilot study of pyridostigmine in constipated patients with autonomic neuropathy

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Analysis of Gut Microbiome and Metabolite Characteristics in Patients with Slow Transit Constipation

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A practical approach to diagnosis and management of functional constipation in adults

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A randomized double-blind placebo-controlled trial showing rifaximin to improve constipation by reducing methane production and accelerating colon transit: A pilot study

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Functional Constipation: Individualising Assessment and Treatment

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Consensus Statement Regarding the Efficacy and Safety of Long-Term Low-Dose Colchicine in Gout and Cardiovascular Disease

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Efficacy and Safety of a Magnesium Sulfate–Rich Natural Mineral Water for Patients With Functional Constipation

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Neurotrophin-3 and neurotrophin-4: The unsung heroes that lies behind the meninges

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Time to treatment response of a magnesium- and sulphate-rich natural mineral water in functional constipation

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Pyridostigmine for the treatment of gastrointestinal symptoms in systemic sclerosis

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Treatment of Chronic Constipation With Colchicine: Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

inferredcites →https://doi.org/10.1016/s0002-9270(03)00252-1openalex-snapshot

Neurotrophin-3 Improves Functional Constipation

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5300 years ago, the Ice Man used natural laxatives and antibiotics

inferredcites →https://doi.org/10.1016/s2468-1253(19)30246-8openalex-snapshot

Efficacy of drugs in chronic idiopathic constipation: a systematic review and network meta-analysis

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Colchicine Is an Effective Treatment for Patients with Chronic Constipation (An Open-Label Trial)

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Lack of Objective Evidence of Efficacy of Laxatives in Chronic Constipation

inferredcites →https://doi.org/10.1038/s41575-019-0167-1openalex-snapshot

First translational consensus on terminology and definitions of colonic motility in animals and humans studied by manometric and other techniques

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Dysbiosis contributes to chronic constipation development via regulation of serotonin transporter in the intestine

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Misoprostol in the treatment of chronic refractory constipation: results of a long‐term open label trial

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New pharmacologic treatments for idiopathic chronic constipation: a financial strain for strainers

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Clinical pharmacology of neuromuscular blocking agents

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The impact of acetylcholinesterase inhibitors on ileus and gut motility following abdominal surgery: a clinical review

inferredcites →https://doi.org/10.1111/apt.13555openalex-snapshot

Letter: orlistat as a potential treatment for chronic idiopathic constipation

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Patient dissatisfaction with medical therapy for chronic constipation or irritable bowel syndrome with constipation: analysis of N‐of‐1 prospective trials in 81 patients

inferredcites →https://doi.org/10.1111/hel.12543openalex-snapshot

Successful Helicobacter pylori eradication therapy improves symptoms of chronic constipation

inferredcites →https://doi.org/10.1111/hel.12863openalex-snapshot

Long‐term improvement in constipation‐related symptoms after Helicobacter pylori eradication therapy

inferredcites →https://doi.org/10.1111/j.1365-2036.1991.tb00522.xopenalex-snapshot

Effects on bowel motility of misoprostol administered before and after meals

inferredcites →https://doi.org/10.1111/j.1365-2036.1995.tb00353.xopenalex-snapshot

The effect of oral vancomycin on chronic idiopathic constipation

inferredcites →https://doi.org/10.1111/j.1365-2982.2011.01709.xopenalex-snapshot

Diagnosis and treatment of chronic constipation - a European perspective

inferredcites →https://doi.org/10.1111/j.1445-5994.1987.tb01232.xopenalex-snapshot

DOES COLCHICINE WORK? THE RESULTS OF THE FIRST CONTROLLED STUDY IN ACUTE GOUT

inferredcites →https://doi.org/10.1111/j.1463-1318.2009.01838.xopenalex-snapshot

The efficacy of treatment of patients with severe constipation or recurrent pseudo‐obstruction with pyridostigmine

inferredcites →https://doi.org/10.1111/j.1526-4637.2005.00053.xopenalex-snapshot

Treatment of Intractable Constipation with Orlistat: A Report of Three Cases

inferredcites →https://doi.org/10.1111/nmo.13762openalex-snapshot

European society of neurogastroenterology and motility guidelines on functional constipation in adults

inferredcites →https://doi.org/10.1136/gutjnl-2012-302483openalex-snapshot

A randomised controlled study of the effect of cholinesterase inhibition on colon function in patients with diabetes mellitus and constipation

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Effects of Sulfate-Rich Mineral Water on Functional Constipation: A Double-Blind, Randomized, Placebo-Controlled Study

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Trimebutine: Mechanism of Action, Effects on Gastrointestinal Function and Clinical Results

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Pharmacological Treatment for Obesity in Adults: An Umbrella Review

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Constipation severity is associated with productivity losses and healthcare utilization in patients with chronic constipation

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Treatment for Constipation—An Online Search. Readability and Quality of Online Patient Resources

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Chronic constipation diagnosis and treatment evaluation: the “CHRO.CO.DI.T.E.” study

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Adverse events during oral colchicine use: a systematic review and meta-analysis of randomised controlled trials

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The varying effects of antibiotics on gut microbiota

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Characterization of gut contractility and microbiota in patients with severe chronic constipation

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Placebo Response in Chronic Idiopathic Constipation: A Systematic Review and Meta-Analysis

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Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial

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A Randomized, Prospective, Comparison Study of Polyethylene Glycol 3350 Without Electrolytes and Milk of Magnesia for Children With Constipation and Fecal Incontinence

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Misoprostol Therapeutics Revisited

inferredcites →https://doi.org/10.2147/ceg.s256364openalex-snapshot

Chronic Idiopathic Constipation in Adults: A Review on Current Guidelines and Emerging Treatment Options

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Orlistat-Associated Adverse Effects and Drug Interactions

inferredcites →https://doi.org/10.2223/jped.2051openalex-snapshot

Comparison of the effectiveness of polyethylene glycol 4000 without electrolytes and magnesium hydroxide in the treatment of chronic functional constipation in children

inferredcites →https://doi.org/10.3390/nu12072052openalex-snapshot

Magnesium Sulfate-Rich Natural Mineral Waters in the Treatment of Functional Constipation–A Review

inferredcites →https://doi.org/10.3390/nu13020421openalex-snapshot

Magnesium Oxide in Constipation

inferredcites →https://doi.org/10.3748/wjg.v9.i8.1874openalex-snapshot

Effects of neurotrophins on gastrointestinal myoelectric activities of rats

inferredcites →https://doi.org/10.4292/wjgpt.v5.i2.77openalex-snapshot

Understanding and treating refractory constipation

inferredcites →https://doi.org/10.5009/gnl19201openalex-snapshot

Potential Strategies in the Prevention of Nonsteroidal Anti-inflammatory Drugs-Associated Adverse Effects in the Lower Gastrointestinal Tract

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Guidelines for the Diagnosis and Treatment of Chronic Functional Constipation in Korea, 2015 Revised Edition

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A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1016/j.fbio.2023.103347openalex-snapshot

Effects of wheat germ polysaccharides prepared by ultra-high pressure on functional constipation and gut microbiota

inferred← citeshttps://doi.org/10.1021/acs.jafc.3c04150openalex-snapshot

Broccoli-Derived Exosome-like Nanoparticles Alleviate Loperamide-Induced Constipation, in Correlation with Regulation on Gut Microbiota and Tryptophan Metabolism

inferred← citeshttps://doi.org/10.1039/d4fo00007bopenalex-snapshot

Integrated metabolic profiles and microbial communities to reveal the beneficial effect of red pitaya on early constipation

inferred← citeshttps://doi.org/10.1080/17474124.2023.2267968openalex-snapshot

Relief from behind: enemas, the back door enforcement to help treating chronic constipation in adults

inferred← citeshttps://doi.org/10.3390/diagnostics15040476openalex-snapshot

The Effectiveness of Transabdominal Ultrasonography in Managing Chronic Constipation in the Elderly, with a Focus on the Underlying Pathological Conditions

inferred← citeshttps://doi.org/10.3390/gidisord7010011openalex-snapshot

Rehabilitation for Chronic Constipation: Integrative Approaches to Diagnosis and Treatment

inferred← citeshttps://doi.org/10.53469/jcmp.2024.06(02).31openalex-snapshot

Progress in the Study of Surgical Treatment of Constipation in Elderly Patients

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