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The Power of Lignans: Plant Compounds with Multifaceted Health-Promoting Effects

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inferredcites →https://doi.org/10.1001/archinte.163.9.1099openalex-snapshot

Risk of Cardiovascular Disease–Related and All-Cause Death According to Serum Concentrations of Enterolactone

inferredcites →https://doi.org/10.1002/advs.202202590openalex-snapshot

Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88‐Dependent Inflammation

inferredcites →https://doi.org/10.1002/bab.2554openalex-snapshot

Intramyocardial delivery of injectable hydrogel with arctigenin alleviated myocardial ischemia–reperfusion injury in rats

inferredcites →https://doi.org/10.1002/cbdv.202402375openalex-snapshot

Plant Origin Source, Content Profile and Bioactivity of Podophyllotoxin as an Important Natural Anticancer Agent

inferredcites →https://doi.org/10.1002/ejlt.200700057openalex-snapshot

Lignan contents in sesame seeds and products

inferredcites →https://doi.org/10.1002/fsn3.3407openalex-snapshot

Effects of sesame (Sesamum indicum L.) and bioactive compounds (sesamin and sesamolin) on inflammation and atherosclerosis: A review

inferredcites →https://doi.org/10.1002/ijc.20119openalex-snapshot

Dietary phytoestrogen intake and premenopausal breast cancer risk in a German case‐control study

inferredcites →https://doi.org/10.1002/jbt.23175openalex-snapshot

Pinoresinol diglucoside ameliorates H/R‐induced injury of cardiomyocytes by regulating miR‐142‐3p and HIF1AN

inferredcites →https://doi.org/10.1002/jcla.24508openalex-snapshot

Arctigenin inhibits apoptosis, extracellular matrix degradation, and inflammation in human nucleus pulposus cells by up‐regulating miR ‐483‐3p

inferredcites →https://doi.org/10.1002/mnfr.202000231openalex-snapshot

Syringaresinol Protects against Type 1 Diabetic Cardiomyopathy by Alleviating Inflammation Responses, Cardiac Fibrosis, and Oxidative Stress

inferredcites →https://doi.org/10.1002/mnfr.202100751openalex-snapshot

Lariciresinol Displays Anti‐Diabetic Activity through Inhibition of α‐Glucosidase and Activation and Enhancement of Insulin Signaling

inferredcites →https://doi.org/10.1002/mnfr.202200771openalex-snapshot

Syringaresinol Alleviates Early Diabetic Retinopathy by Downregulating HIF‐1α/VEGF via Activating Nrf2 Antioxidant Pathway

inferredcites →https://doi.org/10.1002/rcm.9872openalex-snapshot

Characterization of metabolic features and potential anti‐osteoporosis mechanism of pinoresinol diglucoside using metabolite profiling and network pharmacology

inferredcites →https://doi.org/10.1002/tox.23853openalex-snapshot

Sesamin suppresses angiotensin‐II ‐enhanced oxidative stress and hypertrophic markers in H9c2 cells

inferredcites →https://doi.org/10.1007/bf01616377openalex-snapshot

Suppression of phosphoenolpyruvate carboxykinase gene expression by secoisolariciresinol diglucoside (SDG), a new antidiabetic agent

inferredcites →https://doi.org/10.1007/s00198-013-2313-xopenalex-snapshot

NF-κB signaling and bone resorption

inferredcites →https://doi.org/10.1007/s00217-017-2871-9openalex-snapshot

Antioxidant and antimicrobial activity of linseed lignans and phenolic acids

inferredcites →https://doi.org/10.1007/s00284-015-0918-3openalex-snapshot

Antibacterial Mechanism of (−)-Nortrachelogenin in Escherichia coli O157

inferredcites →https://doi.org/10.1007/s00394-021-02736-4openalex-snapshot

Lignan exposure: a worldwide perspective

inferredcites →https://doi.org/10.1007/s00394-025-03588-yopenalex-snapshot

Assessing the combined effects of Black Cohosh, Soy Isoflavones, and SDG Lignans on menopausal symptoms: a randomized, double-blind, placebo-controlled clinical trial

inferredcites →https://doi.org/10.1007/s10059-010-0072-5openalex-snapshot

Anti-Candida property of a lignan glycoside derived from Styrax japonica S. et Z. via membrane-active mechanisms

inferredcites →https://doi.org/10.1007/s10549-009-0681-xopenalex-snapshot

Dietary lignan intakes in relation to survival among women with breast cancer: the Western New York Exposures and Breast Cancer (WEB) Study

inferredcites →https://doi.org/10.1007/s10549-018-5021-6openalex-snapshot

The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth

inferredcites →https://doi.org/10.1007/s10552-007-9089-2openalex-snapshot

Dietary phytoestrogen intake—lignans and isoflavones—and breast cancer risk (Canada)

inferredcites →https://doi.org/10.1007/s10565-023-09790-0openalex-snapshot

Syringaresinol protects against diabetic nephropathy by inhibiting pyroptosis via NRF2-mediated antioxidant pathway

inferredcites →https://doi.org/10.1007/s10753-017-0631-4openalex-snapshot

Schisandrin B Ameliorates Myocardial Ischemia/Reperfusion Injury Through Attenuation of Endoplasmic Reticulum Stress-Induced Apoptosis

inferredcites →https://doi.org/10.1007/s10753-021-01587-9openalex-snapshot

Syringaresinol Resisted Sepsis-Induced Acute Lung Injury by Suppressing Pyroptosis Via the Oestrogen Receptor-β Signalling Pathway

inferredcites →https://doi.org/10.1007/s11011-022-01031-3openalex-snapshot

Preventive effects of arctigenin from Arctium lappa L against LPS-induced neuroinflammation and cognitive impairments in mice

inferredcites →https://doi.org/10.1007/s11011-023-01191-wopenalex-snapshot

Effects of sesamin on Aβ1-42-induced oxidative stress and LTP impairment in a rat model of Alzheimer's disease

inferredcites →https://doi.org/10.1007/s11101-016-9469-xopenalex-snapshot

Chemical diversity and pharmacological significance of the secondary metabolites of nutmeg (Myristica fragrans Houtt.)

inferredcites →https://doi.org/10.1007/s11101-021-09758-0openalex-snapshot

Plant-derived lignans as potential antiviral agents: a systematic review

inferredcites →https://doi.org/10.1007/s11906-018-0812-zopenalex-snapshot

The Global Epidemic of the Metabolic Syndrome

inferredcites →https://doi.org/10.1007/s11914-024-00883-1openalex-snapshot

Lignans from Sambucus williamsii Protect Bone Via Microbiome

inferredcites →https://doi.org/10.1007/s12272-013-0048-zopenalex-snapshot

Multiple biological properties of macelignan and its pharmacological implications

inferredcites →https://doi.org/10.1007/s12272-019-01186-1openalex-snapshot

Schisandrin A ameliorates MPTP-induced Parkinson’s disease in a mouse model via regulation of brain autophagy

inferredcites →https://doi.org/10.1016/0031-9422(96)00024-6openalex-snapshot

Antiviral activity of lignans and their glycosides from Justicia procumbens

inferredcites →https://doi.org/10.1016/j.acthis.2013.11.005openalex-snapshot

Honokiol suppresses TNF-α-induced migration and matrix metalloproteinase expression by blocking NF-κB activation via the ERK signaling pathway in rat aortic smooth muscle cells

inferredcites →https://doi.org/10.1016/j.apsb.2022.07.019openalex-snapshot

Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis

inferredcites →https://doi.org/10.1016/j.archoralbio.2022.105546openalex-snapshot

In vitro evaluation of the antibacterial and cytotoxic activities of the Euclea natalensis crude extract and fractions against oral infection agents

inferredcites →https://doi.org/10.1016/j.atherosclerosis.2004.11.012openalex-snapshot

Hypocholesterolemic and antiatherosclerotic effect of flax lignan complex isolated from flaxseed

inferredcites →https://doi.org/10.1016/j.bbadis.2025.167728openalex-snapshot

Exploring the protective mechanisms of syringaresinol against myocardial infarction by experimental validation and network pharmacology

inferredcites →https://doi.org/10.1016/j.bbrc.2015.11.041openalex-snapshot

Arctigenin reduces blood pressure by modulation of nitric oxide synthase and NADPH oxidase expression in spontaneously hypertensive rats

inferredcites →https://doi.org/10.1016/j.bbrc.2021.12.088openalex-snapshot

(+)-Sesamin, a sesame lignan, is a potent inhibitor of gut bacterial tryptophan indole-lyase that is a key enzyme in chronic kidney disease pathogenesis

inferredcites →https://doi.org/10.1016/j.bbrc.2022.02.057openalex-snapshot

Honokiol improves endothelial function in type 2 diabetic rats via alleviating oxidative stress and insulin resistance

inferredcites →https://doi.org/10.1016/j.bcp.2020.114366openalex-snapshot

Akt and calcium-permeable AMPA receptor are involved in the effect of pinoresinol on amyloid β-induced synaptic plasticity and memory deficits

inferredcites →https://doi.org/10.1016/j.biopha.2017.01.123openalex-snapshot

Sesamin imparts neuroprotection against intrastriatal 6-hydroxydopamine toxicity by inhibition of astroglial activation, apoptosis, and oxidative stress

inferredcites →https://doi.org/10.1016/j.biopha.2017.05.130openalex-snapshot

(−)-Kusunokinin and piperloguminine from Piper nigrum: An alternative option to treat breast cancer

inferredcites →https://doi.org/10.1016/j.biopha.2017.10.145openalex-snapshot

An overview of neuroprotective and cognitive enhancement properties of lignans from Schisandra chinensis

inferredcites →https://doi.org/10.1016/j.biopha.2018.08.037openalex-snapshot

Sesamin and sesamolin reduce amyloid-β toxicity in a transgenic Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.biopha.2019.108922openalex-snapshot

Schisandrin A inhibits triple negative breast cancer cells by regulating Wnt/ER stress signaling pathway

inferredcites →https://doi.org/10.1016/j.biopha.2023.114964openalex-snapshot

Secoisolariciresinol diglucoside Ameliorates Osteoarthritis via Nuclear factor-erythroid 2-related factor-2/ nuclear factor kappa B Pathway: In vitro and in vivo experiments

inferredcites →https://doi.org/10.1016/j.biopha.2023.116107openalex-snapshot

Additive renal protective effects between arctigenin and puerarin in diabetic kidney disease

inferredcites →https://doi.org/10.1016/j.brainresbull.2021.04.012openalex-snapshot

Sesamin suppresses advanced glycation end products induced microglial reactivity using BV2 microglial cell line as a model

inferredcites →https://doi.org/10.1016/j.cardiores.2003.11.038openalex-snapshot

Nuclear factor κB: a potential therapeutic target in atherosclerosis and thrombosis

inferredcites →https://doi.org/10.1016/j.cbi.2019.04.032openalex-snapshot

Honokiol post-treatment ameliorates myocardial ischemia/reperfusion injury by enhancing autophagic flux and reducing intracellular ROS production

inferredcites →https://doi.org/10.1016/j.cbi.2025.111634openalex-snapshot

Investigating podophyllotoxin-induced cardiotoxicity in rats by Toxicological Evidence Chain (TEC): Focus on the Akt1/Srebp-1c/PUFAs axis

inferredcites →https://doi.org/10.1016/j.cbpc.2023.109637openalex-snapshot

Sesamin lacks zebrafish embryotoxicity but exhibits evidence of anti-angiogenesis, anti-oxidant and anti-inflammatory activities

inferredcites →https://doi.org/10.1016/j.ecl.2013.09.009openalex-snapshot

Metabolic Syndrome

inferredcites →https://doi.org/10.1016/j.ejphar.2008.06.026openalex-snapshot

Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer

inferredcites →https://doi.org/10.1016/j.ejphar.2014.07.057openalex-snapshot

Phytoestrogens and their effects

inferredcites →https://doi.org/10.1016/j.ejphar.2020.173311openalex-snapshot

(−)-Kusunokinin inhibits breast cancer in N-nitrosomethylurea-induced mammary tumor rats

inferredcites →https://doi.org/10.1016/j.ejphar.2021.174644openalex-snapshot

Syringaresinol attenuates sepsis-induced cardiac dysfunction by inhibiting inflammation and pyroptosis in mice

inferredcites →https://doi.org/10.1016/j.ejphar.2025.177424openalex-snapshot

Arctiin attenuated NASH by inhibiting glycolysis and inflammation via FGFR2/CSF1R signaling

inferredcites →https://doi.org/10.1016/j.fct.2007.05.017openalex-snapshot

Antioxidant activities of the flaxseed lignan secoisolariciresinol diglucoside, its aglycone secoisolariciresinol and the mammalian lignans enterodiol and enterolactone in vitro

inferredcites →https://doi.org/10.1016/j.fct.2019.01.017openalex-snapshot

The effects of pinoresinol on cholinergic dysfunction-induced memory impairments and synaptic plasticity in mice

inferredcites →https://doi.org/10.1016/j.fct.2021.112733openalex-snapshot

Secoisolariciresinol diglucoside mitigates benzo[a]pyrene-induced liver and kidney toxicity in mice via miR-101a/MKP-1-mediated p38 and ERK pathway

inferredcites →https://doi.org/10.1016/j.fitote.2013.08.005openalex-snapshot

New lignan esters from Alyxia schlechteri and antifungal activity against Pythium insidiosum

inferredcites →https://doi.org/10.1016/j.fitote.2015.11.010openalex-snapshot

Lignans from the roots of Acorus tatarinowii Schott ameliorate β amyloid-induced toxicity in transgenic Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.fitote.2019.104388openalex-snapshot

Anti-HIV-1 activities of constituents from the rhizomes of Boesenbergia thorelii

inferredcites →https://doi.org/10.1016/j.fitote.2024.106311openalex-snapshot

Tracheloside, the main constituent of the total lignan extract from Trachelospermi Caulis, inhibited rheumatoid arthritis via IL-17/MAPK signaling pathway

inferredcites →https://doi.org/10.1016/j.foodres.2011.12.023openalex-snapshot

Plant and mammalian lignans: A review of source, intake, metabolism, intestinal bacteria and health

inferredcites →https://doi.org/10.1016/j.freeradbiomed.2009.07.018openalex-snapshot

Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury

inferredcites →https://doi.org/10.1016/j.heliyon.2024.e32899openalex-snapshot

An insight into the anticancer potentials of lignan arctiin: A comprehensive review of molecular mechanisms

inferredcites →https://doi.org/10.1016/j.indcrop.2004.06.003openalex-snapshot

Antifungal lignans from the creosotebush (Larrea tridentata)

inferredcites →https://doi.org/10.1016/j.intimp.2020.106759openalex-snapshot

Inhibition of programmed death ligand 1 (PD-L1) expression in breast cancer cells by sesamin

inferredcites →https://doi.org/10.1016/j.intimp.2022.109529openalex-snapshot

Arctigenin mitigates insulin resistance by modulating the IRS2/GLUT4 pathway via TLR4 in type 2 diabetes mellitus mice

inferredcites →https://doi.org/10.1016/j.intimp.2023.109982openalex-snapshot

Syringaresinol attenuates osteoarthritis via regulating the NF-κB pathway

inferredcites →https://doi.org/10.1016/j.intimp.2024.112660openalex-snapshot

Schisandrin B alleviates angiotensin II-induced cardiac inflammatory remodeling by inhibiting the recruitment of MyD88 to TLRs in mouse cardiomyocytes

inferredcites →https://doi.org/10.1016/j.jacc.2021.05.049openalex-snapshot

Lignan Intake and Risk of Coronary Heart Disease

inferredcites →https://doi.org/10.1016/j.jep.2014.04.031openalex-snapshot

Effects of total lignans from Eucommia ulmoides barks prevent bone loss in vivo and in vitro

inferredcites →https://doi.org/10.1016/j.jep.2021.113920openalex-snapshot

Pinoresinol diglucoside (PDG) attenuates cardiac hypertrophy via AKT/mTOR/NF-κB signaling in pressure overload-induced rats

inferredcites →https://doi.org/10.1016/j.jep.2025.119335openalex-snapshot

Lignans from Schisandra chinensis (Turcz.) Baill ameliorates cognitive impairment in Alzheimer's disease and alleviates ferroptosis by activating the Nrf2/FPN1 signaling pathway and regulating iron levels

inferredcites →https://doi.org/10.1016/j.jff.2022.105376openalex-snapshot

Schisandrin ameliorates diabetic nephropathy via regulating of PI3K/Akt/NF-κB-mediated inflammation and TGF-β1-induced fibrosis in HFD/STZ-induced C57BL/6J mice

inferredcites →https://doi.org/10.1016/j.jff.2024.106642openalex-snapshot

Dietary secoisolariciresinol diglucoside ameliorates high-fat diet-induced atherosclerosis via regulating immunological inflammation and reshaping gut microbiota in ApoE-/- mice

inferredcites →https://doi.org/10.1016/j.jgr.2021.08.003openalex-snapshot

Syringaresinol derived from Panax ginseng berry attenuates oxidative stress-induced skin aging via autophagy

inferredcites →https://doi.org/10.1016/j.jnutbio.2018.10.006openalex-snapshot

(+)-Sesamin attenuates chronic unpredictable mild stress-induced depressive-like behaviors and memory deficits via suppression of neuroinflammation

inferredcites →https://doi.org/10.1016/j.jnutbio.2019.06.004openalex-snapshot

Dietary flaxseed protects against ventricular arrhythmias and left ventricular dilation after a myocardial infarction

inferredcites →https://doi.org/10.1016/j.lfs.2021.120121openalex-snapshot

Arctigenin alleviates cadmium-induced nephrotoxicity: Targeting endoplasmic reticulum stress, Nrf2 signaling, and the associated inflammatory response

inferredcites →https://doi.org/10.1016/j.lwt.2017.12.003openalex-snapshot

Assessment of phenolic compounds in virgin olive oil by response surface methodology with particular focus on flavonoids and lignans

inferredcites →https://doi.org/10.1016/j.mce.2023.112029openalex-snapshot

Schisandrin B, a potential GLP-1R agonist, exerts anti-diabetic effects by stimulating insulin secretion

inferredcites →https://doi.org/10.1016/j.mcna.2015.01.006openalex-snapshot

Menopause

inferredcites →https://doi.org/10.1016/j.micpath.2017.10.040openalex-snapshot

The natural compound magnolol affects growth, biofilm formation, and ultrastructure of oral Candida isolates

inferredcites →https://doi.org/10.1016/j.neulet.2023.137090openalex-snapshot

Neuroprotective potential of Honokiol in ICV-STZ induced neuroinflammation, Aβ (1−42) and NF-kB expression in experimental model of rats

inferredcites →https://doi.org/10.1016/j.numecd.2007.05.007openalex-snapshot

The effect of a lignan complex isolated from flaxseed on inflammation markers in healthy postmenopausal women

inferredcites →https://doi.org/10.1016/j.nut.2019.04.006openalex-snapshot

Neuroprotective effects of lignan 7-hydroxymatairesinol (HMR/lignan) in a rodent model of Parkinson's disease

inferredcites →https://doi.org/10.1016/j.nutres.2010.06.004openalex-snapshot

Flaxseed lignan lowers blood cholesterol and decreases liver disease risk factors in moderately hypercholesterolemic men

inferredcites →https://doi.org/10.1016/j.pharep.2018.01.003openalex-snapshot

Protective and therapeutic activity of honokiol in reversing motor deficits and neuronal degeneration in the mouse model of Parkinson’s disease

inferredcites →https://doi.org/10.1016/j.phymed.2004.06.017openalex-snapshot

In vivo anti-osteoporotic activity of isotaxiresinol, a lignan from wood of Taxus yunnanensis

inferredcites →https://doi.org/10.1016/j.phymed.2012.11.011openalex-snapshot

Antidiabetic effect of secoisolariciresinol diglucoside in streptozotocin-induced diabetic rats

inferredcites →https://doi.org/10.1016/j.phymed.2018.09.022openalex-snapshot

Lignan and flavonoid support the prevention of cinnamon against oxidative stress related diseases

inferredcites →https://doi.org/10.1016/j.phymed.2019.152955openalex-snapshot

Schizandrin B attenuates angiotensin II induced endothelial to mesenchymal transition in vascular endothelium by suppressing NF-κB activation

inferredcites →https://doi.org/10.1016/j.phymed.2022.154124openalex-snapshot

Lignans from Eucommia ulmoides Oliver leaves exhibit neuroprotective effects via activation of the PI3K/Akt/GSK-3β/Nrf2 signaling pathways in H2O2-treated PC-12 cells

inferredcites →https://doi.org/10.1016/j.phymed.2023.155292openalex-snapshot

(–)-Syringaresinol attenuates ulcerative colitis by improving intestinal epithelial barrier function and inhibiting inflammatory responses

inferredcites →https://doi.org/10.1016/j.phymed.2024.155372openalex-snapshot

Schisandrin A alleviates renal fibrosis by inhibiting PKCβ and oxidative stress

inferredcites →https://doi.org/10.1016/j.phymed.2024.155655openalex-snapshot

Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept

inferredcites →https://doi.org/10.1016/j.phymed.2024.156054openalex-snapshot

Matairesinol blunts adverse cardiac remodeling and heart failure induced by pressure overload by regulating Prdx1 and PI3K/AKT/FOXO1 signaling

inferredcites →https://doi.org/10.1016/j.phymed.2024.156146openalex-snapshot

Lignans of Schisandra chinensis (Turcz.) Baill inhibits Parkinson's disease progression through mediated neuroinflammation-TRPV1 expression in microglia

inferredcites →https://doi.org/10.1016/j.phymed.2025.156624openalex-snapshot

Sauchinone preserves cardiac function in doxorubicin-induced cardiomyopathy by inhibiting the NLRP3 inflammasome

inferredcites →https://doi.org/10.1016/j.phymed.2025.156780openalex-snapshot

Schisandrin B ameliorates Alzheimer's disease by suppressing neuronal ferroptosis and ensuing microglia M1 polarization

inferredcites →https://doi.org/10.1016/j.phyplu.2021.100038openalex-snapshot

Protective role of flaxseed lignan secoisolariciresinol diglucoside against lead-acetate-induced oxidative-stress-mediated nephrotoxicity in rats

inferredcites →https://doi.org/10.1016/j.phyplu.2024.100625openalex-snapshot

The protective effects of sesamin against metabolic syndrome: A mechanistic review

inferredcites →https://doi.org/10.1016/j.phytochem.2015.06.021openalex-snapshot

Natural lignans from Arctium lappa as antiaging agents in Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.phytol.2016.10.022openalex-snapshot

Antimicrobial lignans derived from the roots of Streblus asper

inferredcites →https://doi.org/10.1016/j.psychres.2016.04.120openalex-snapshot

Inflammatory cytokines and nuclear factor-kappa B activation in adolescents with bipolar and major depressive disorders

inferredcites →https://doi.org/10.1016/j.taap.2018.09.005openalex-snapshot

Schisandrin B exhibits potent anticancer activity in triple negative breast cancer by inhibiting STAT3

inferredcites →https://doi.org/10.1016/j.taap.2024.116884openalex-snapshot

Pinoresinol diglucoside mitigates dexamethasone-induced osteoporosis and chondrodysplasia in zebrafish

inferredcites →https://doi.org/10.1016/j.tice.2024.102440openalex-snapshot

Schisandrin inhibits VSMCs proliferation and migration by arresting cell cycle and targeting JAK2 to regulating the JAK2/STAT3 pathway

inferredcites →https://doi.org/10.1016/j.urology.2015.07.024openalex-snapshot

Urinary Lignans Are Associated With Decreased Incontinence in Postmenopausal Women

inferredcites →https://doi.org/10.1016/j.yjmcc.2007.09.014openalex-snapshot

Secoisolariciresinol diglucoside induces neovascularization-mediated cardioprotection against ischemia–reperfusion injury in hypercholesterolemic myocardium

inferredcites →https://doi.org/10.1016/s0021-9150(97)00239-6openalex-snapshot

Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alpha-linolenic acid

inferredcites →https://doi.org/10.1016/s0955-2863(02)00172-9openalex-snapshot

Soy isoflavones’ osteoprotective role in postmenopausal women: mechanism of action

inferredcites →https://doi.org/10.1016/s1570-0232(02)00092-2openalex-snapshot

Enterolignans

inferredcites →https://doi.org/10.1016/s1674-6384(14)60005-8openalex-snapshot

Antidiabetic and Anti-oxidative Effects of Honokiol on Diabetic Rats Induced by High-fat Diet and Streptozotocin

inferredcites →https://doi.org/10.1017/s0007114507871649openalex-snapshot

Dietary flaxseed lignan extract lowers plasma cholesterol and glucose concentrations in hypercholesterolaemic subjects

inferredcites →https://doi.org/10.1017/s0007114508061527openalex-snapshot

Effects of a flaxseed-derived lignan supplement on C-reactive protein, IL-6 and retinol-binding protein 4 in type 2 diabetic patients

inferredcites →https://doi.org/10.1017/s0007114509992753openalex-snapshot

Health effects with consumption of the flax lignan secoisolariciresinol diglucoside

inferredcites →https://doi.org/10.1021/acs.jmedchem.1c01073openalex-snapshot

Development of Membrane-Active Honokiol/Magnolol Amphiphiles as Potent Antibacterial Agents against Methicillin-Resistant Staphylococcus aureus (MRSA)

inferredcites →https://doi.org/10.1021/acs.jnatprod.8b00590openalex-snapshot

Lignan Dimers from Forsythia viridissima Roots and Their Antiviral Effects

inferredcites →https://doi.org/10.1021/acschemneuro.7b00071openalex-snapshot

Effect of the Biphenyl Neolignan Honokiol on Aβ42-Induced Toxicity in Caenorhabditis elegans, Aβ42 Fibrillation, Cholinesterase Activity, DPPH Radicals, and Iron(II) Chelation

inferredcites →https://doi.org/10.1021/acsomega.3c07636openalex-snapshot

Stability and Bioaccessibility of Lignans in Food Products

inferredcites →https://doi.org/10.1021/acsomega.4c03738openalex-snapshot

Exploring the Molecular Mechanism of Schisandrin C for the Treatment of Atherosclerosis via the PI3K/AKT/mTOR Autophagy Pathway

inferredcites →https://doi.org/10.1021/jf0207979openalex-snapshot

Identification and Stereochemical Characterization of Lignans in Flaxseed and Pumpkin Seeds

inferredcites →https://doi.org/10.1021/jf0629134openalex-snapshot

Quantification of a Broad Spectrum of Lignans in Cereals, Oilseeds, and Nuts

inferredcites →https://doi.org/10.1021/jf9004274openalex-snapshot

Characterization of Variation in the Lignan Content and Composition of Winter Rye, Spring Wheat, and Spring Oat

inferredcites →https://doi.org/10.1038/aps.2018.32openalex-snapshot

Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L

inferredcites →https://doi.org/10.1038/s41374-019-0340-8openalex-snapshot

Arctigenin alleviates myocardial infarction injury through inhibition of the NFAT5-related inflammatory phenotype of cardiac macrophages/monocytes in mice

inferredcites →https://doi.org/10.1038/s41598-017-07407-1openalex-snapshot

Antidepressant-like effects and cognitive enhancement of Schisandra chinensis in chronic unpredictable mild stress mice and its related mechanism

inferredcites →https://doi.org/10.1038/s41598-023-50453-1openalex-snapshot

Daily supplement of sesame oil prevents postmenopausal osteoporosis via maintaining serum estrogen and aromatase levels in rats

inferredcites →https://doi.org/10.1038/s41598-024-83383-7openalex-snapshot

Arctiin alleviates knee osteoarthritis by suppressing chondrocyte oxidative stress induced by accumulated iron via AKT/NRF2/HO-1 signaling pathway

inferredcites →https://doi.org/10.1038/s41598-025-89895-0openalex-snapshot

In vivo and in vitro investigations of schisandrin B against angiotensin II induced ferroptosis and atrial fibrosis by regulation of the SIRT1 pathway

inferredcites →https://doi.org/10.1038/sj.bjc.6605003openalex-snapshot

Lignans and breast cancer risk in pre- and post-menopausal women: meta-analyses of observational studies

inferredcites →https://doi.org/10.1039/c7fo00204aopenalex-snapshot

Sesamin prevents apoptosis and inflammation after experimental myocardial infarction by JNK and NF-κB pathways

inferredcites →https://doi.org/10.1039/c9fo00677jopenalex-snapshot

Urinary and plasmatic metabolomics strategy to explore the holistic mechanism of lignans in S. chinensis in treating Alzheimer's disease using UPLC-Q-TOF-MS

inferredcites →https://doi.org/10.1039/d1fo04037eopenalex-snapshot

Secoisolariciresinol diglucoside ameliorates high fat diet-induced colon inflammation and regulates gut microbiota in mice

inferredcites →https://doi.org/10.1042/bsr20211067openalex-snapshot

Sauchinone inhibits the proliferation, migration and invasion of breast cancer cells by suppressing Akt-CREB-MMP13 signaling pathway

inferredcites →https://doi.org/10.1055/s-0042-100915openalex-snapshot

Polycyclic Spiro Lignans and Biphenyl Tetrahydrofuranone Lignans from Gymnotheca involucrata

inferredcites →https://doi.org/10.1055/s-0042-107471openalex-snapshot

Arctigenin Attenuates Learning and Memory Deficits through PI3k/Akt/GSK-3β Pathway Reducing Tau Hyperphosphorylation in Aβ-Induced AD Mice

inferredcites →https://doi.org/10.1055/s-2006-962087openalex-snapshot

The Antiviral Action of Lignans

inferredcites →https://doi.org/10.1056/nejm199508033330502openalex-snapshot

Meta-Analysis of the Effects of Soy Protein Intake on Serum Lipids

inferredcites →https://doi.org/10.1056/nejmra000471openalex-snapshot

Production and Actions of Estrogens

inferredcites →https://doi.org/10.1067/mlc.2001.115717openalex-snapshot

Secoisolariciresinol diglucoside from flaxseed delays the development of type 2 diabetes in Zucker rat

inferredcites →https://doi.org/10.1079/bjn20041154openalex-snapshot

Dietary secoisolariciresinol diglucoside and its oligomers with 3-hydroxy-3-methyl glutaric acid decrease vitamin E levels in rats

inferredcites →https://doi.org/10.1079/bjn20051371openalex-snapshot

Lignan contents of Dutch plant foods: a database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol

inferredcites →https://doi.org/10.1080/01616412.2020.1782079openalex-snapshot

Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition

inferredcites →https://doi.org/10.1080/01635580903532440openalex-snapshot

The Effect of Secoisolariciresinol Diglucoside and Flaxseed Oil, Alone and in Combination, on MCF-7 Tumor Growth and Signaling Pathways

inferredcites →https://doi.org/10.1080/07315724.2017.1342213openalex-snapshot

Influence of Flaxseed Lignan Supplementation to Older Adults on Biochemical and Functional Outcome Measures of Inflammation

inferredcites →https://doi.org/10.1080/08923973.2024.2425028openalex-snapshot

Matairesinol repolarizes M2 macrophages to M1 phenotype to induce apoptosis in triple-negative breast cancer cells

inferredcites →https://doi.org/10.1080/09513590601010722openalex-snapshot

Short-term effects of a combination of isoflavones, lignans andCimicifuga racemosaon climacteric-related symptoms in postmenopausal women: A double-blind, randomized, placebo-controlled trial

inferredcites →https://doi.org/10.1080/1028415x.2019.1596613openalex-snapshot

Sesamin and sesamol attenuate H 2 O 2 -induced oxidative stress on human neuronal cells via the SIRT1-SIRT3-FOXO3a signaling pathway

inferredcites →https://doi.org/10.1080/10286020.2018.1467894openalex-snapshot

Potent leishmanicidal and antibacterial metabolites from Olea ferruginea

inferredcites →https://doi.org/10.1080/13813455.2025.2535723openalex-snapshot

Honokiol prevents central kainic acid-induced neurodegeneration by suppressing oxidative stress, inflammation, and TGF-β1 expression

inferredcites →https://doi.org/10.1080/14786419.2020.1826479openalex-snapshot

Antiestrogenic and antiproliferative potency of secoisolariciresinol diglucoside derivatives on MCF-7 breast cancer cells

inferredcites →https://doi.org/10.1080/14786419.2024.2356661openalex-snapshot

New lignans from Phyllanthodendron dunnianum

inferredcites →https://doi.org/10.1080/21655979.2021.1982307openalex-snapshot

Bio-informatics and in Vitro Experiments Reveal the Mechanism of Schisandrin A Against MDA-MB-231 cells

inferredcites →https://doi.org/10.1093/ajcn/68.6.1333sopenalex-snapshot

Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones

inferredcites →https://doi.org/10.1093/carcin/20.9.1831openalex-snapshot

Exposure to flaxseed or its lignan component during different developmental stages influences rat mammary gland structures

inferredcites →https://doi.org/10.1093/jpp/rgad114openalex-snapshot

Arctigenin attenuated spatial memory impairment in pR5 mice by regulating mitochondrial energy metabolism

inferredcites →https://doi.org/10.1093/nutrit/nuaa043openalex-snapshot

Dietary phytoestrogens and biomarkers of their intake in relation to cancer survival and recurrence: a comprehensive systematic review with meta-analysis

inferredcites →https://doi.org/10.1093/nutrit/nuae089openalex-snapshot

Effects of Sesamin in Animal Models of Obesity-Associated Diseases: A Systematic Review and Meta-Analysis

inferredcites →https://doi.org/10.1097/gme.0b013e31818fc00aopenalex-snapshot

Flaxseed combined with low-dose estrogen therapy preserves bone tissue in ovariectomized rats

inferredcites →https://doi.org/10.1097/wnr.0000000000001583openalex-snapshot

Pinoresinol diglucoside attenuates neuroinflammation, apoptosis and oxidative stress in a mice model with Alzheimer’s disease

inferredcites →https://doi.org/10.1099/jgv.0.000432openalex-snapshot

Trachelogenin, a novel inhibitor of hepatitis C virus entry through CD81

inferredcites →https://doi.org/10.1111/1440-1681.13187openalex-snapshot

Sauchinone inhibits angiotensin II‐induced proliferation and migration of vascular smooth muscle cells

inferredcites →https://doi.org/10.1111/1750-3841.16816openalex-snapshot

Anti‐osteoporosis effects of mammalian lignans and their precursors from flaxseed and safflower seed using zebrafish model

inferredcites →https://doi.org/10.1111/1759-7714.14834openalex-snapshot

Sauchinone inhibits breast cancer cell proliferation through regulating microRNA ‐148a‐3p/ HER ‐2 axis

inferredcites →https://doi.org/10.1111/cbdd.13956openalex-snapshot

Pinoresinol diglucoside alleviates ischemia/reperfusion‐induced brain injury by modulating neuroinflammation and oxidative stress

inferredcites →https://doi.org/10.1111/cbdd.14268openalex-snapshot

Lariciresinol protects rats from complete Freund's adjuvant induced arthritis in rats via modulation of transforming growth factor‐β and nuclear factor kappa B pathway: An in vivo and in silico study

inferredcites →https://doi.org/10.1111/cbdd.14625openalex-snapshot

Arctigenin Modulates Adipogenic‐Osteogenic Balance in the Bone Marrow Microenvironment of Ovariectomized Rats via the MEK1 / PPARγ /Wnt/β‐Catenin Pathway

inferredcites →https://doi.org/10.1111/cns.14249openalex-snapshot

Arctigenin improves neuropathy via ameliorating apoptosis and modulating autophagy in streptozotocin‐induced diabetic mice

inferredcites →https://doi.org/10.1111/cns.14878openalex-snapshot

Honokiol relieves hippocampal neuronal damage in Alzheimer's disease by activating the SIRT3‐mediated mitochondrial autophagy

inferredcites →https://doi.org/10.1111/ijcp.14360openalex-snapshot

Efficacy and safety of phytoestrogens in the treatment of perimenopausal and postmenopausal depressive disorders: A systematic review and meta‐analysis

inferredcites →https://doi.org/10.1111/j.1472-765x.2010.02900.xopenalex-snapshot

The synergy of honokiol and fluconazole against clinical isolates of azole-resistant Candida albicans

inferredcites →https://doi.org/10.1111/j.1541-4337.2009.00105.xopenalex-snapshot

Flaxseed Lignans: Source, Biosynthesis, Metabolism, Antioxidant Activity, Bio‐Active Components, and Health Benefits

inferredcites →https://doi.org/10.1111/j.1753-4887.2010.00319.xopenalex-snapshot

Dietary lignans: physiology and potential for cardiovascular disease risk reduction

inferredcites →https://doi.org/10.1111/jcmm.15686openalex-snapshot

Honokiol ameliorates angiotensin II‐induced hypertension and endothelial dysfunction by inhibiting HDAC6‐mediated cystathionine γ‐lyase degradation

inferredcites →https://doi.org/10.1111/jcmm.18028openalex-snapshot

Honokiol ameliorates angiotensin II ‐induced cardiac hypertrophy by promoting dissociation of the Nur77–LKB1 complex and activating the AMPK pathway

inferredcites →https://doi.org/10.1111/jfbc.14180openalex-snapshot

Comparative effects of sesame lignans (sesamin, sesamolin, and sesamol) on oxidative stress and lipid metabolism in steatosis HepG2 cells

inferredcites →https://doi.org/10.1124/jpet.106.114165openalex-snapshot

Secoisolariciresinol Diglucoside: Relevance to Angiogenesis and Cardioprotection against Ischemia-Reperfusion Injury

inferredcites →https://doi.org/10.1139/h08-142openalex-snapshot

A randomized controlled trial of the effects of flaxseed lignan complex on metabolic syndrome composite score and bone mineral in older adults

inferredcites →https://doi.org/10.1142/s0192415x24500721openalex-snapshot

Honokiol Exhibits Anti-Tumor Effects in Breast Cancer by Modulating the miR-148a-5p-CYP1B1 Axis

inferredcites →https://doi.org/10.1155/2018/3159801openalex-snapshot

Honokiol Ameliorates Myocardial Ischemia/Reperfusion Injury in Type 1 Diabetic Rats by Reducing Oxidative Stress and Apoptosis through Activating the SIRT1‐Nrf2 Signaling Pathway

inferredcites →https://doi.org/10.1155/2020/2172740openalex-snapshot

A Comprehensive Review on Schisandrin B and Its Biological Properties

inferredcites →https://doi.org/10.1155/2020/3621261openalex-snapshot

Secoisolariciresinol Diglucoside Exerts Anti-Inflammatory and Antiapoptotic Effects through Inhibiting the Akt/IκB/NF-κB Pathway on Human Umbilical Vein Endothelial Cells

inferredcites →https://doi.org/10.1155/2021/5598980openalex-snapshot

The Ameliorative Effects of Arctiin and Arctigenin on the Oxidative Injury of Lung Induced by Silica via TLR‐4/NLRP3/TGF‐β Signaling Pathway

inferredcites →https://doi.org/10.1155/2021/8129512openalex-snapshot

Schisandrin Protects against Norepinephrine-Induced Myocardial Hypertrophic Injury by Inhibiting the JAK2/STAT3 Signaling Pathway

inferredcites →https://doi.org/10.1155/2022/1001692openalex-snapshot

Honokiol Provides Cardioprotection from Myocardial Ischemia/Reperfusion Injury (MI/RI) by Inhibiting Mitochondrial Apoptosis via the PI3K/AKT Signaling Pathway

inferredcites →https://doi.org/10.1155/2022/3541731openalex-snapshot

Ameliorative Effects of Arctigenin on Pulmonary Fibrosis Induced by Bleomycin via the Antioxidant Activity

inferredcites →https://doi.org/10.1155/2022/5623555openalex-snapshot

Schisandrin B Diet Inhibits Oxidative Stress to Reduce Ferroptosis and Lipid Peroxidation to Prevent Pirarubicin‐Induced Hepatotoxicity

inferredcites →https://doi.org/10.1155/2023/1116841openalex-snapshot

Sesamin Protects against APAP-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Inflammatory Response via Deactivation of HMGB1/TLR4/NFκB Signal in Mice

inferredcites →https://doi.org/10.1159/000480320openalex-snapshot

Honokiol Attenuates Oligomeric Amyloid β1-42-Induced Alzheimer’s Disease in Mice Through Attenuating Mitochondrial Apoptosis and Inhibiting the Nuclear Factor Kappa-B Signaling Pathway

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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Advancing justicidin B delivery by cinnamyl-functionalized polymeric micelles

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Anti-inflammatory Potential of Dietary Components and Benefits in Alzheimer’s Disease

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Exploring the associations between lifestyle and dietary patterns with preclinical alzheimer’s disease: findings from La Rioja cohort study

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Urinary phytoestrogen metabolites are associated with a reduced risk of hyperuricemia

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Plant-derived molecules as multitarget modulators of NF-κB, PI3K/Akt, MAPK, and AMPK/mTOR signaling in chronic diseases

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Pinnatifolin from Syringa pinnatifolia protects against myocardial ischemic injury in mice by targeting GPX4 to suppress ferroptosis

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Integrated widely targeted UPLC-MS/MS metabolomics and transcriptomics reveal MYB-linked variation in bioactive phenolics across five kiwifruit varieties

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Bioactive compounds and socio-demographics factors in functional foods and nutraceuticals

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Wood-derived lignans magnolol and honokiol improve nutrient utilization in broilers and regulate inflammation and epithelial repair in vitro

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Chemical constituents of bird cherry ( Prunus padus L.) stemwood and knotwood bioactive-rich extracts and their antioxidant activity

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Polyphenols as Therapeutic Candidates in the 21 st Century: From Chemical Discovery to Clinical Translation

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Natural Compounds of Plant Origin–Promising Agents in the Fight Against Antibiotic Resistance

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PLANT-DERIVED PHYTOCONSTITUENTS WITH ANTI-BREAST CANCER POTENTIAL: MECHANISTIC INSIGHTS, EVALUATION, AND THERAPEUTIC IMPLICATIONS

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Neuroprotective Potential of Sesamum indicum in a Multifactorial In Vitro Neuron–Astrocyte System Exposed to Chronic Stress Mediators

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Reduced Neuroinflammation and Pain with a Functional Sourdough Bread Enriched with Legumes and Ancient Cereals in a Mouse Model of LPS-Induced Inflammation

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Dietary Polyphenols in Brain Aging: Molecular Mechanisms and Implications for Neurodegeneration

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Bioactive Anti-Inflammatory Compounds and Therapeutic Strategies for Promoting Resolution

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