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Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/advs.201801807openalex-snapshotA pH/ROS Cascade‐Responsive Charge‐Reversal Nanosystem with Self‐Amplified Drug Release for Synergistic Oxidation‐Chemotherapy
inferredcites →https://doi.org/10.1002/ijc.11344openalex-snapshotResveratrol analog (Z)‐3,5,4′‐trimethoxystilbene is a potent anti‐mitotic drug inhibiting tubulin polymerization
inferredcites →https://doi.org/10.1002/mnfr.200700252openalex-snapshotThe grape and wine constituent piceatannol inhibits proliferation of human bladder cancer cells via blocking cell cycle progression and inducing Fas/membrane bound Fas ligand‐mediated apoptotic pathway
inferredcites →https://doi.org/10.1002/mnfr.200800123openalex-snapshotResveratrol analog‐3,5,4′‐trimethoxy‐trans‐stilbene inhibits invasion of human lung adenocarcinoma cells by suppressing the MAPK pathway and decreasing matrix metalloproteinase‐2 expression
inferredcites →https://doi.org/10.1006/taap.2002.9438openalex-snapshotInhibition of Poly(ADP-ribose) Polymerase Activation Attenuates β-Lapachone-Induced Necrotic Cell Death in Human Osteosarcoma Cells
inferredcites →https://doi.org/10.1016/j.bcp.2009.06.109openalex-snapshot2,3′,4,4′,5′-Pentamethoxy-trans-stilbene, a resveratrol derivative, is a potent inducer of apoptosis in colon cancer cells via targeting microtubules
inferredcites →https://doi.org/10.1016/j.biocel.2009.08.005openalex-snapshotThe resveratrol analogue 4,4′-dihydroxy-trans-stilbene inhibits cell proliferation with higher efficiency but different mechanism from resveratrol
inferredcites →https://doi.org/10.1016/j.bmc.2016.01.024openalex-snapshotNovel naphtho[2,1-d]oxazole-4,5-diones as NQO1 substrates with improved aqueous solubility: Design, synthesis, and in vivo antitumor evaluation
inferredcites →https://doi.org/10.1016/j.ejmech.2014.07.079openalex-snapshotSynthesis and evaluation of the cytotoxic activity of 1,2-furanonaphthoquinones tethered to 1,2,3-1H-triazoles in myeloid and lymphoid leukemia cell lines
inferredcites →https://doi.org/10.1016/j.ejmech.2019.06.056openalex-snapshotSynthesis of quinones with highlighted biological applications: A critical update on the strategies towards bioactive compounds with emphasis on lapachones
inferredcites →https://doi.org/10.1016/j.ejpb.2012.12.019openalex-snapshotAdministration of the optimized β-Lapachone–poloxamer–cyclodextrin ternary system induces apoptosis, DNA damage and reduces tumor growth in a human breast adenocarcinoma xenograft mouse model
inferredcites →https://doi.org/10.1016/j.ejphar.2008.03.027openalex-snapshotTrans- and cis-stilbene polyphenols induced rapid perinuclear mitochondrial clustering and p53-independent apoptosis in cancer cells but not normal cells
inferredcites →https://doi.org/10.1016/j.taap.2013.07.019openalex-snapshot3,5,4′-Trimethoxystilbene, a natural methoxylated analog of resveratrol, inhibits breast cancer cell invasiveness by downregulation of PI3K/Akt and Wnt/β-catenin signaling cascades and reversal of epithelial–mesenchymal transition
inferredcites →https://doi.org/10.1016/j.tiv.2008.03.002openalex-snapshotCytotoxic activity of 3,3′,4,4′,5,5′-hexahydroxystilbene against breast cancer cells is mediated by induction of p53 and downregulation of mitochondrial superoxide dismutase
inferredcites →https://doi.org/10.1016/j.tiv.2017.06.004openalex-snapshotThe effect of resveratrol, its naturally occurring derivatives and tannic acid on the induction of cell cycle arrest and apoptosis in rat C6 and human T98G glioma cell lines
inferredcites →https://doi.org/10.1021/ar900179topenalex-snapshotLigand Binding and Hydration in Protein Misfolding: Insights from Studies of Prion and p53 Tumor Suppressor Proteins
inferredcites →https://doi.org/10.1021/jf030073copenalex-snapshotGrape Polyphenol Resveratrol and the Related Molecule 4-Hydroxystilbene Induce Growth Inhibition, Apoptosis, S-Phase Arrest, and Upregulation of Cyclins A, E, and B1 in Human SK-Mel-28 Melanoma Cells
inferredcites →https://doi.org/10.1021/jf101571zopenalex-snapshotPterostilbene Inhibits Colorectal Aberrant Crypt Foci (ACF) and Colon Carcinogenesis via Suppression of Multiple Signal Transduction Pathways in Azoxymethane-Treated Mice
inferredcites →https://doi.org/10.1021/jf4004175openalex-snapshotLong-Term Ethanol Exposure-Induced Hepatocellular Carcinoma Cell Migration and Invasion through Lysyl Oxidase Activation Are Attenuated by Combined Treatment with Pterostilbene and Curcumin Analogues
inferredcites →https://doi.org/10.1021/jf900531mopenalex-snapshotMechanisms of Apoptotic Effects Induced by Resveratrol, Dibenzoylmethane, and Their Analogues on Human Lung Carcinoma Cells
inferredcites →https://doi.org/10.1021/jf903067gopenalex-snapshot3,5,3′,4′,5′-Pentamethoxystilbene (MR-5), a Synthetically Methoxylated Analogue of Resveratrol, Inhibits Growth and Induces G1 Cell Cycle Arrest of Human Breast Carcinoma MCF-7 Cells
inferredcites →https://doi.org/10.1021/np300893nopenalex-snapshotCytotoxicity and Modulation of Cancer-Related Signaling by (Z)- and (E)-3,4,3′,5′-Tetramethoxystilbene Isolated from Eugenia rigida
inferredcites →https://doi.org/10.1038/cddis.2014.202openalex-snapshotβ-Lapachone induces programmed necrosis through the RIP1-PARP-AIF-dependent pathway in human hepatocellular carcinoma SK-Hep1 cells
inferredcites →https://doi.org/10.1038/s41388-018-0584-6openalex-snapshotDHS (trans−4,4′-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2)
inferredcites →https://doi.org/10.1038/srep32627openalex-snapshot3′-hydroxy-3,4,5,4′-tetramethoxystilbene, the metabolite of resveratrol analogue DMU-212, inhibits ovarian cancer cell growth in vitro and in a mice xenograft model
inferredcites →https://doi.org/10.1039/c1ob05209hopenalex-snapshotSynthesis of new 9-hydroxy-α- and 7-hydroxy-β-pyran naphthoquinones and cytotoxicity against cancer cell lines
inferredcites →https://doi.org/10.1074/jbc.m117.813923openalex-snapshotThe NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism
inferredcites →https://doi.org/10.1080/02656730903049836openalex-snapshotHeat shock increases expression of NAD(P)H:quinone oxidoreductase (NQO1), mediator of β-lapachone cytotoxicity, by increasing NQO1 gene activity and via Hsp70-mediated stabilisation of NQO1 protein
inferredcites →https://doi.org/10.1089/jmf.2006.9.161openalex-snapshotβ -Lapachone, a Quinone Isolated from Tabebuia avellanedae, Induces Apoptosis in HepG2 Hepatoma Cell Line Through Induction of Bax and Activation of Caspase
inferredcites →https://doi.org/10.1093/carcin/bgp121openalex-snapshotPterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells
inferredcites →https://doi.org/10.1093/jn/132.2.298openalex-snapshotPiceatannol, a Natural Analog of Resveratrol, Inhibits Progression through the S Phase of the Cell Cycle in Colorectal Cancer Cell Lines
inferredcites →https://doi.org/10.1124/jpet.116.232694openalex-snapshotβ-Lapachone Induces NAD(P)H:Quinone Oxidoreductase-1– and Oxidative Stress–Dependent Heat Shock Protein 90 Cleavage and Inhibits Tumor Growth and Angiogenesis
inferredcites →https://doi.org/10.1124/mol.59.4.784openalex-snapshotInduction of CDK Inhibitors (p21 WAF1 and p27 Kip1 ) and Bak in the β-Lapachone-Induced Apoptosis of Human Prostate Cancer Cells
inferredcites →https://doi.org/10.1155/2017/3634915openalex-snapshotChemopreventive Potential of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside on the Formation of Aberrant Crypt Foci in Azoxymethane-Induced Colorectal Cancer in Rats
inferredcites →https://doi.org/10.1158/1078-0432.ccr-06-1528openalex-snapshotPterostilbene, an Active Constituent of Blueberries, Suppresses Aberrant Crypt Foci Formation in the Azoxymethane-Induced Colon Carcinogenesis Model in Rats
inferredcites →https://doi.org/10.1158/1535-7163.11.3.1openalex-snapshotSignal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines
inferredcites →https://doi.org/10.1159/000358696openalex-snapshotResveratrol Reduces the Proinflammatory Effects and Lipopolysaccharide- Induced Expression of HMGB1 and TLR4 in RAW264.7 Cells
inferredcites →https://doi.org/10.1186/1471-2407-5-97openalex-snapshotNovel curcumin- and emodin-related compounds identified by in silico 2D/3D conformer screening induce apoptosis in tumor cells
inferredcites →https://doi.org/10.1186/1476-4598-3-11openalex-snapshotComparison of gene expression in HCT116 treatment derivatives generated by two different 5-fluorouracil exposure protocols.
inferredcites →https://doi.org/10.18632/oncotarget.17879openalex-snapshottrans-4,4’-Dihydroxystilbene (DHS) inhibits human neuroblastoma tumor growth and induces mitochondrial and lysosomal damages in neuroblastoma cell lines
inferredcites →https://doi.org/10.2147/dddt.s186028openalex-snapshotThe synergistic effect of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside combined with Adriamycin on MCF-7 breast cancer cells
inferredcites →https://doi.org/10.2147/ijn.s163929openalex-snapshotNanostructured lipid carriers co-delivering lapachone and doxorubicin for overcoming multidrug resistance in breast cancer therapy
inferredcites →https://doi.org/10.2174/1573406414666180524071409openalex-snapshotDesign, Synthesis and Biological Evaluation of 1H-1,2,3-Triazole-Linked-1H-Dibenzo[b,h]xanthenes as Inductors of ROS-Mediated Apoptosis in the Breast Cancer Cell Line MCF-7
inferredcites →https://doi.org/10.3389/fonc.2019.00352openalex-snapshotDietary Polyphenols, Resveratrol and Pterostilbene Exhibit Antitumor Activity on an HPV E6-Positive Cervical Cancer Model: An in vitro and in vivo Analysis
inferredcites →https://doi.org/10.3390/ijms141122483openalex-snapshotSynthetic Resveratrol Analogue, 3,3',4,4',5,5'-Hexahydroxy-trans-Stilbene, Accelerates Senescence in Peritoneal Mesothelium and Promotes Senescence-Dependent Growth of Gastrointestinal Cancers
inferredcites →https://doi.org/10.3390/molecules25010228openalex-snapshotPterostilbene Suppresses both Cancer Cells and Cancer Stem-Like Cells in Cervical Cancer with Superior Bioavailability to Resveratrol
inferredcites →https://doi.org/10.3892/ijo.2016.3574openalex-snapshot2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside suppresses human colorectal cancer cell metastasis through inhibiting NF-κB activation
inferredcites →https://doi.org/10.3892/ijo.2016.3635openalex-snapshotThe resveratrol analogue, 3,4,5,4′-trans-tetramethoxystilbene, inhibits the growth of A375 melanoma cells through multiple anticancer modes of action
inferredcites →https://doi.org/10.3892/mmr.2017.7680openalex-snapshot2,3,5,4-tetrahydroxy diphenylethylene-2-O-glucoside inhibits the adhesion and invasion of A549 human lung cancer cells
inferredcites →https://doi.org/10.3892/or.19.6.1621openalex-snapshotNovel resveratrol analogs induce apoptosis and cause cell cycle arrest in HT29 human colon cancer cells: Inhibition of ribonucleotide reductase activity
inferredcites →https://doi.org/10.4103/0973-1482.158035openalex-snapshot(Z)-3,4,3',5'-tetramethoxystilbene, a natural product, induces apoptosis and reduces viability of paclitaxel-and cisplatin-resistant osteosarcoma cells
inferredcites →https://doi.org/10.5483/bmbrep.2003.36.2.223openalex-snapshotSuppression of Human Prostate Cancer Cell Growth by β-Lapachone via Down-regulation of pRB Phosphorylation and Induction of Cdk Inhibitor p21WAF1/CIP1
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/ddr.70128openalex-snapshotBeta‐Lapachone: Effects on Proliferation, Survival, Migration, Cell Cycle, and lncRNA Modulation in Bladder Cancer Cells With Distinct TP53 Profiles
inferred← citeshttps://doi.org/10.1007/s13577-026-01427-8openalex-snapshotCytotoxic and genotoxic effects of oxime β-lapachone in human cancer cells: selectivity toward NCI-H460 and insights from molecular docking
inferred← citeshttps://doi.org/10.1021/acs.analchem.0c04508openalex-snapshotNormalization of Samples of Limited Amounts in Quantitative Metabolomics Using Liquid Chromatography Fluorescence Detection with Dansyl Labeling of Metabolites
inferred← citeshttps://doi.org/10.1021/jacs.5c17598openalex-snapshotControlled Self-Immolative Release of β-Lapachone via an Optimized para -Hydroxybenzyl Linker for Targeted Pancreatic Cancer Therapy
inferred← citeshttps://doi.org/10.1111/jfbc.13710openalex-snapshotReprogramming of erythrocyte lifespan by NFκB‐TNFα naphthoquinone antagonist β‐lapachone is regulated by calcium overload and CK1α
inferred← citeshttps://doi.org/10.1371/journal.pone.0265068openalex-snapshotAntitubercular activity assessment of fluorinated chalcones, 2-aminopyridine-3-carbonitrile and 2-amino-4H-pyran-3-carbonitrile derivatives: In vitro, molecular docking and in-silico drug likeliness studies
inferred← citeshttps://doi.org/10.2174/1381612829666230403133322openalex-snapshotResveratrol Attenuates Hydrogen Peroxide-induced Injury of Rat Ovarian Granulosa-lutein Cells by Resisting Oxidative Stress via the SIRT1/Nrf2/ARE Signaling Pathway
inferred← citeshttps://doi.org/10.3390/ijms24129867openalex-snapshotβ-Lapachone Exerts Anticancer Effects by Downregulating p53, Lys-Acetylated Proteins, TrkA, p38 MAPK, SOD1, Caspase-2, CD44 and NPM in Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells
inferred← citeshttps://doi.org/10.3390/immuno4020009openalex-snapshotAnti-Inflammatory Efficacy of Resveratrol-Enriched Rice Callus Extract on Lipopolysaccharide-Stimulated RAW264.7 Macrophages
inferred← citeshttps://doi.org/10.3390/molecules25215045openalex-snapshotWine Intake in the Framework of a Mediterranean Diet and Chronic Non-Communicable Diseases: A Short Literature Review of the Last 5 Years
inferred← citeshttps://doi.org/10.3390/molecules27020349openalex-snapshotModern Approaches in the Discovery and Development of Plant-Based Natural Products and Their Analogues as Potential Therapeutic Agents
inferred← citeshttps://doi.org/10.3390/nu12051327openalex-snapshotThe Effect of 4′-hydroxy-3,4,5-trimetoxystilbene, the Metabolite of Resveratrol Analogue DMU-212, on Growth, Cell Cycle and Apoptosis in DLD-1 and LOVO Colon Cancer Cell Lines
inferred← citeshttps://doi.org/10.3390/plants13233385openalex-snapshotCoinhibitory Effects of Resveratrol- and Protopanaxadiol-Enriched Rice Seed Extracts Against Melanogenic Activities in Melan-a Cells
inferred← citeshttps://doi.org/10.34172/ps.2021.29openalex-snapshotTrado-Medical uses, Chemical Constituents and Biological Activities of Newbouldia laevis (Bignoniaceae): A Review
inferred← citeshttps://doi.org/10.4103/pm.pm_251_22openalex-snapshotLapachol and (α/β)-lapachone as inhibitors of SARS-CoV-2 main protease (Mpro) and hACE-2: ADME properties, docking and dynamic simulation approaches
inferred← citeshttps://doi.org/10.5530/ijper.20250091openalex-snapshotAnticancer, Apoptotic, Cell Migration and Invasion Inhibition and in silico Molecular Docking Studies of Naringetol in A-549 Human Lung Cancer Cells
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