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Fatty Acid Synthase: An Emerging Target in Cancer

https://doi.org/10.3390/molecules25173935

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Outgoing claims: the papers this work cites, builds on, or argues with.

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High expression of Fatty Acid‐Binding Protein 5 promotes cell growth and metastatic potential of colorectal cancer cells

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Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model

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Exogenous fatty acid binding protein 4 promotes human prostate cancer cell progression

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The effect of FASN inhibition on the growth and metabolism of a cisplatin‐resistant ovarian carcinoma model

inferredcites →https://doi.org/10.1002/j.1552-4604.1995.tb04034.xopenalex-snapshot

Review of Limited Systemic Absorption of Orlistat, a Lipase Inhibitor, in Healthy Human Volunteers

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Anti‐Tumorigenic Potential of a Novel Orlistat‐AICAR Combination in Prostate Cancer Cells

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Down‐regulation of PKM2 decreases FASN expression in bladder cancer cells through AKT/mTOR/SREBP‐1c axis

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New insights into the structure and function of fatty acid-binding proteins

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Metabolism and signaling activities of nuclear lipids

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Loss of fatty acid synthase suppresses the malignant phenotype of colorectal cancer cells by down-regulating energy metabolism and mTOR signaling pathway

inferredcites →https://doi.org/10.1007/s10549-007-9678-5openalex-snapshot

Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75

inferredcites →https://doi.org/10.1007/s11060-014-1452-zopenalex-snapshot

Overexpression of fatty acid synthase in human gliomas correlates with the WHO tumor grade and inhibition with Orlistat reduces cell viability and triggers apoptosis

inferredcites →https://doi.org/10.1007/s11307-012-0587-6openalex-snapshot

Metabolic Shifts Induced by Fatty Acid Synthase Inhibitor Orlistat in Non-small Cell Lung Carcinoma Cells Provide Novel Pharmacodynamic Biomarkers for Positron Emission Tomography and Magnetic Resonance Spectroscopy

inferredcites →https://doi.org/10.1007/s11745-004-1329-9openalex-snapshot

Structure and function of animal fatty acid synthase

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Factors affecting the chain length of fatty acids synthesised by lactating-rabbit mammary glands

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Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

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Factors effecting the chain-length of fatty acids synthesized by lactating-rabbit mammary glands

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Novel Nuclear Localization of Fatty Acid Synthase Correlates with Prostate Cancer Aggressiveness

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Anticancer properties of the fatty acid synthase inhibitor TVB-3166 on oral squamous cell carcinoma cell lines

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Mitochondrial fatty acid synthesis and respiration

inferredcites →https://doi.org/10.1016/j.bbagen.2012.07.010openalex-snapshot

Fatty acid synthase inhibitor orlistat induces apoptosis in T cell lymphoma: Role of cell survival regulatory molecules

inferredcites →https://doi.org/10.1016/j.bbalip.2011.09.017openalex-snapshot

Fatty acid synthase and liver triglyceride metabolism: Housekeeper or messenger?

inferredcites →https://doi.org/10.1016/j.bbalip.2016.08.011openalex-snapshot

Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology

inferredcites →https://doi.org/10.1016/j.bbrc.2013.09.024openalex-snapshot

Inhibition of fatty acid synthase suppresses U-2 OS cell invasion and migration via downregulating the activity of HER2/PI3K/AKT signaling pathway in vitro

inferredcites →https://doi.org/10.1016/j.bbrc.2015.05.108openalex-snapshot

Up-regulation of fatty acid synthase induced by EGFR/ERK activation promotes tumor growth in pancreatic cancer

inferredcites →https://doi.org/10.1016/j.biochi.2004.09.018openalex-snapshot

SREBP transcription factors: master regulators of lipid homeostasis

inferredcites →https://doi.org/10.1016/j.cell.2011.02.013openalex-snapshot

Hallmarks of Cancer: The Next Generation

inferredcites →https://doi.org/10.1016/j.celrep.2016.02.004openalex-snapshot

Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer

inferredcites →https://doi.org/10.1016/j.cmet.2005.04.002openalex-snapshot

“New” hepatic fat activates PPARα to maintain glucose, lipid, and cholesterol homeostasis

inferredcites →https://doi.org/10.1016/j.cmet.2010.09.010openalex-snapshot

Atherogenic Lipids and Lipoproteins Trigger CD36-TLR2-Dependent Apoptosis in Macrophages Undergoing Endoplasmic Reticulum Stress

inferredcites →https://doi.org/10.1016/j.devcel.2008.10.015openalex-snapshot

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

inferredcites →https://doi.org/10.1016/j.ebiom.2015.06.020openalex-snapshot

Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression

inferredcites →https://doi.org/10.1016/j.gene.2018.07.035openalex-snapshot

Diverse roles of fatty acid binding proteins (FABPs) in development and pathogenesis of cancers

inferredcites →https://doi.org/10.1016/j.jhep.2014.10.039openalex-snapshot

Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease

inferredcites →https://doi.org/10.1016/j.stem.2020.04.002openalex-snapshot

FASN-Dependent Lipid Metabolism Links Neurogenic Stem/Progenitor Cell Activity to Learning and Memory Deficits

inferredcites →https://doi.org/10.1016/j.tcb.2007.08.006openalex-snapshot

Regulation of mitochondrial fusion and division

inferredcites →https://doi.org/10.1016/j.urology.2012.02.046openalex-snapshot

Inhibition of Fatty-acid Synthase Suppresses P-AKT and Induces Apoptosis in Bladder Cancer

inferredcites →https://doi.org/10.1016/s0005-2760(97)00205-1openalex-snapshot

Physiological properties and functions of intracellular fatty acid-binding proteins

inferredcites →https://doi.org/10.1016/s0021-9258(19)50272-1openalex-snapshot

CD36 is a receptor for oxidized low density lipoprotein

inferredcites →https://doi.org/10.1016/s0022-2275(20)31637-0openalex-snapshot

Defect in human myocardial long-chain fatty acid uptake is caused by FAT/CD36 mutations

inferredcites →https://doi.org/10.1016/s0022-2275(20)39738-8openalex-snapshot

Human fatty acid synthase mRNA: tissue distribution, genetic mapping, and kinetics of decay after glucose deprivation

inferredcites →https://doi.org/10.1016/s0092-8674(00)81683-9openalex-snapshot

The Hallmarks of Cancer

inferredcites →https://doi.org/10.1016/s1535-6108(04)00055-8openalex-snapshot

The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer

inferredcites →https://doi.org/10.1021/acs.chemrestox.8b00269openalex-snapshot

Orlistat Displays Antitumor Activity and Enhances the Efficacy of Paclitaxel in Human Hepatoma Hep3B Cells

inferredcites →https://doi.org/10.1021/ol500206wopenalex-snapshot

In Situ Proteome Profiling of C75, a Covalent Bioactive Compound with Potential Anticancer Activities

inferredcites →https://doi.org/10.1038/aps.2011.40openalex-snapshot

A novel positive feedback loop involving FASN/p-ERK1/2/5-LOX/LTB4/FASN sustains high growth of breast cancer cells

inferredcites →https://doi.org/10.1038/bjc.1979.120openalex-snapshot

Lipogenetic and glycolytic enzyme activities in carcinoma and nonmalignant diseases of the human breast

inferredcites →https://doi.org/10.1038/bjc.2012.355openalex-snapshot

The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas

inferredcites →https://doi.org/10.1038/labinvest.2010.157openalex-snapshot

Inhibition of fatty acid synthase in melanoma cells activates the intrinsic pathway of apoptosis

inferredcites →https://doi.org/10.1038/ncb3039openalex-snapshot

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

inferredcites →https://doi.org/10.1038/nrd2589openalex-snapshot

Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets

inferredcites →https://doi.org/10.1038/nsmb1265openalex-snapshot

Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat

inferredcites →https://doi.org/10.1038/oncsis.2017.4openalex-snapshot

Fatty acid synthase regulates estrogen receptor-α signaling in breast cancer cells

inferredcites →https://doi.org/10.1038/pcan.2012.15openalex-snapshot

Targeted therapy with fatty acid synthase inhibitors in a human prostate carcinoma LNCaP/tk-luc-bearing animal model

inferredcites →https://doi.org/10.1038/s41388-017-0093-zopenalex-snapshot

Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis

inferredcites →https://doi.org/10.1038/s41388-018-0384-zopenalex-snapshot

CPT1A-mediated fatty acid oxidation promotes colorectal cancer cell metastasis by inhibiting anoikis

inferredcites →https://doi.org/10.1038/s41388-020-1156-0openalex-snapshot

Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis

inferredcites →https://doi.org/10.1038/s41389-018-0107-xopenalex-snapshot

CD36 plays a critical role in proliferation, migration and tamoxifen-inhibited growth of ER-positive breast cancer cells

inferredcites →https://doi.org/10.1038/s41418-021-00768-1openalex-snapshot

Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy

inferredcites →https://doi.org/10.1038/s41419-019-1550-0openalex-snapshot

FASN activity is important for the initial stages of the induction of senescence

inferredcites →https://doi.org/10.1038/s41467-019-11327-1openalex-snapshot

Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis

inferredcites →https://doi.org/10.1038/s41586-019-1715-0openalex-snapshot

In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer

inferredcites →https://doi.org/10.1038/s41598-019-49486-2openalex-snapshot

Fatty Acid Inhibition Sensitizes Androgen-Dependent and -Independent Prostate Cancer to Radiotherapy via FASN/NF-κB Pathway

inferredcites →https://doi.org/10.1038/srep14752openalex-snapshot

Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma

inferredcites →https://doi.org/10.1038/srep18669openalex-snapshot

Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers

inferredcites →https://doi.org/10.1038/srep46569openalex-snapshot

Fatty acid synthase cooperates with protrudin to facilitate membrane outgrowth of cellular protrusions

inferredcites →https://doi.org/10.1042/bj1150807openalex-snapshot

The effect of dietary fat on lipogenesis in mammary gland and liver from lactating and virgin mice

inferredcites →https://doi.org/10.1054/clnu.2002.0565openalex-snapshot

Degree of in vivo inhibition of human gastric and pancreatic lipases by Orlistat (Tetrahydrolipstatin, THL) in the stomach and small intestine

inferredcites →https://doi.org/10.1073/pnas.0931394100openalex-snapshot

Fatty acid synthesis is essential in embryonic development: Fatty acid synthase null mutants and most of the heterozygotes die in utero

inferredcites →https://doi.org/10.1073/pnas.1205995109openalex-snapshot

Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma

inferredcites →https://doi.org/10.1073/pnas.1501605112openalex-snapshot

Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors

inferredcites →https://doi.org/10.1073/pnas.1609934113openalex-snapshot

FASN regulates cellular response to genotoxic treatments by increasing PARP-1 expression and DNA repair activity via NF-κB and SP1

inferredcites →https://doi.org/10.1073/pnas.1617709114openalex-snapshot

Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma

inferredcites →https://doi.org/10.1073/pnas.91.14.6379openalex-snapshot

Fatty acid synthesis: a potential selective target for antineoplastic therapy.

inferredcites →https://doi.org/10.1073/pnas.95.11.5987openalex-snapshot

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

inferredcites →https://doi.org/10.1073/pnas.96.24.13656openalex-snapshot

Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

inferredcites →https://doi.org/10.1074/jbc.m008556200openalex-snapshot

Progesterone Stimulates Adipocyte Determination and Differentiation 1/Sterol Regulatory Element-binding Protein 1c Gene Expression

inferredcites →https://doi.org/10.1074/jbc.m109.007526openalex-snapshot

CD36 Is a Novel Serum Amyloid A (SAA) Receptor Mediating SAA Binding and SAA-induced Signaling in Human and Rodent Cells

inferredcites →https://doi.org/10.1074/jbc.m111.272732openalex-snapshot

Identification of a New Fatty Acid Synthesis-Transport Machinery at the Peroxisomal Membrane

inferredcites →https://doi.org/10.1074/jbc.m111421200openalex-snapshot

Diminished Hepatic Response to Fasting/Refeeding and Liver X Receptor Agonists in Mice with Selective Deficiency of Sterol Regulatory Element-binding Protein-1c

inferredcites →https://doi.org/10.1074/jbc.m310991200openalex-snapshot

C75, a Fatty Acid Synthase Inhibitor, Modulates AMP-activated Protein Kinase to Alter Neuronal Energy Metabolism

inferredcites →https://doi.org/10.1074/jbc.m405924200openalex-snapshot

Platelet-derived Growth Factor Stimulates Membrane Lipid Synthesis Through Activation of Phosphatidylinositol 3-Kinase and Sterol Regulatory Element-binding Proteins

inferredcites →https://doi.org/10.1080/01635581.2013.748923openalex-snapshot

Fatty Acid Synthase Inhibition Induces Differential Expression of Genes Involved in Apoptosis and Cell Proliferation in Ocular Cancer Cells

inferredcites →https://doi.org/10.1080/1120009x.2019.1694761openalex-snapshot

Fatty acid synthase inhibitor orlistat impairs cell growth and down-regulates PD-L1 expression of a human T-cell leukemia line

inferredcites →https://doi.org/10.1080/15384101.2019.1629792openalex-snapshot

De novo lipogenesis at the mitotic exit is used for nuclear envelope reassembly/expansion. Implications for combined chemotherapy

inferredcites →https://doi.org/10.1080/17460441.2016.1245286openalex-snapshot

Recent advances in targeting the fatty acid biosynthetic pathway using fatty acid synthase inhibitors

inferredcites →https://doi.org/10.1093/cvr/cvn098openalex-snapshot

Transcriptional control of mitochondrial biogenesis: the central role of PGC-1

inferredcites →https://doi.org/10.1111/j.1365-2184.2007.00498.xopenalex-snapshot

Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells

inferredcites →https://doi.org/10.1111/j.1365-2796.2007.01825.xopenalex-snapshot

PPARs and their metabolic modulation: new mechanisms for transcriptional regulation?

inferredcites →https://doi.org/10.1126/science.123.3191.309openalex-snapshot

On the Origin of Cancer Cells

inferredcites →https://doi.org/10.1126/science.288.5475.2379openalex-snapshot

Reduced Food Intake and Body Weight in Mice Treated with Fatty Acid Synthase Inhibitors

inferredcites →https://doi.org/10.1126/science.aav0173openalex-snapshot

Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation

inferredcites →https://doi.org/10.1126/scisignal.2000446openalex-snapshot

EGFR Signaling Through an Akt-SREBP-1–Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy

inferredcites →https://doi.org/10.1152/ajpendo.00514.2013openalex-snapshot

Fatty acid synthase is required for mammary gland development and milk production during lactation

inferredcites →https://doi.org/10.1152/ajplung.1989.257.4.l195openalex-snapshot

Fatty acid biosynthesis in developing fetal lung

inferredcites →https://doi.org/10.1152/physiolgenomics.00020.2006openalex-snapshot

Metabolic regulation in the lactating mammary gland: a lipid synthesizing machine

inferredcites →https://doi.org/10.1155/2015/838652openalex-snapshot

Docosahexaenoic Acid Modulates a HER2-Associated Lipogenic Phenotype, Induces Apoptosis, and Increases Trastuzumab Action in HER2-Overexpressing Breast Carcinoma Cells

inferredcites →https://doi.org/10.1155/2019/5702026openalex-snapshot

High Membranous Expression of Fatty Acid Transport Protein 4 Is Associated with Tumorigenesis and Tumor Progression in Clear Cell Renal Cell Carcinoma

inferredcites →https://doi.org/10.1158/0008-5472.can-06-1794openalex-snapshot

Inhibition of Fatty Acid Synthase Induces Endoplasmic Reticulum Stress in Tumor Cells

inferredcites →https://doi.org/10.1158/0008-5472.can-16-1597openalex-snapshot

Destabilization of Fatty Acid Synthase by Acetylation Inhibits De Novo Lipogenesis and Tumor Cell Growth

inferredcites →https://doi.org/10.1158/1078-0432.ccr-16-2770openalex-snapshot

Overexpressed Fatty Acid Synthase in Gastrointestinal Stromal Tumors: Targeting a Progression-Associated Metabolic Driver Enhances the Antitumor Effect of Imatinib

inferredcites →https://doi.org/10.1158/1535-7163.mct-09-1061openalex-snapshot

Inhibition of Fatty Acid Synthase Suppresses c-Met Receptor Kinase and Induces Apoptosis in Diffuse Large B-Cell Lymphoma

inferredcites →https://doi.org/10.1158/1535-7163.mct-12-1136openalex-snapshot

The Fatty Acid Synthase Inhibitor Orlistat Reduces the Growth and Metastasis of Orthotopic Tongue Oral Squamous Cell Carcinomas

inferredcites →https://doi.org/10.1158/2159-8290.cd-17-1371openalex-snapshot

Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins

inferredcites →https://doi.org/10.1159/000342967openalex-snapshot

Fatty Acid Synthase Is a Potential Therapeutic Target in Estrogen Receptor-/Progesterone Receptor-Positive Endometrioid Endometrial Cancer

inferredcites →https://doi.org/10.1165/rcmb.2009-0349ocopenalex-snapshot

Roles of Peroxisome Proliferator–Activated Receptor–α and –γ in the Development of Non–Small Cell Lung Cancer

inferredcites →https://doi.org/10.1172/jci118645openalex-snapshot

Human fatty acid synthesis is stimulated by a eucaloric low fat, high carbohydrate diet.

inferredcites →https://doi.org/10.1172/jci118951openalex-snapshot

Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.

inferredcites →https://doi.org/10.1172/jci2961openalex-snapshot

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

inferredcites →https://doi.org/10.1172/jci31183openalex-snapshot

Brain fatty acid synthase activates PPARα to maintain energy homeostasis

inferredcites →https://doi.org/10.1172/jci6223openalex-snapshot

Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

inferredcites →https://doi.org/10.1186/1471-2164-8-168openalex-snapshot

Genome-wide changes accompanying knockdown of fatty acid synthase in breast cancer

inferredcites →https://doi.org/10.1186/1471-2407-11-302openalex-snapshot

Fatty acid binding proteins (FABPs) in prostate, bladder and kidney cancer cell lines and the use of IL-FABP as survival predictor in patients with renal cell carcinoma

inferredcites →https://doi.org/10.1186/1471-2407-12-280openalex-snapshot

Different fatty acid metabolism effects of (−)-Epigallocatechin-3-Gallate and C75 in Adenocarcinoma lung cancer

inferredcites →https://doi.org/10.1186/bcr2777openalex-snapshot

Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells

inferredcites →https://doi.org/10.1186/s12944-019-1058-8openalex-snapshot

Inhibition of FASN suppresses the malignant biological behavior of non-small cell lung cancer cells via deregulating glucose metabolism and AKT/ERK pathway

inferredcites →https://doi.org/10.1186/s13046-019-1049-7openalex-snapshot

CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3β/β-catenin pathway

inferredcites →https://doi.org/10.1194/jlr.m036103openalex-snapshot

Nutrient-dependent phosphorylation channels lipid synthesis to regulate PPARα

inferredcites →https://doi.org/10.1194/jlr.r067595openalex-snapshot

The role of ER stress in lipid metabolism and lipotoxicity

inferredcites →https://doi.org/10.1200/jco.2015.33.15_suppl.tps2615openalex-snapshot

First-in-human investigation of the oral first-in-class fatty acid synthase (FASN) inhibitor, TVB-2640.

inferredcites →https://doi.org/10.1210/en.2006-0486openalex-snapshot

Targeting Fatty Acid Synthase in Breast and Endometrial Cancer: An Alternative to Selective Estrogen Receptor Modulators?

inferredcites →https://doi.org/10.1210/me.15.10.1817openalex-snapshot

Androgens Stimulate Lipogenic Gene Expression in Prostate Cancer Cells by Activation of the Sterol Regulatory Element-Binding Protein Cleavage Activating Protein/Sterol Regulatory Element-Binding Protein Pathway

inferredcites →https://doi.org/10.1210/me.2005-0479openalex-snapshot

Androgen Activation of the Sterol Regulatory Element-Binding Protein Pathway: Current Insights

inferredcites →https://doi.org/10.1371/journal.pone.0033738openalex-snapshot

Blockade of Fatty Acid Synthase Triggers Significant Apoptosis in Mantle Cell Lymphoma

inferredcites →https://doi.org/10.1371/journal.pone.0082396openalex-snapshot

Myelopoietic Efficacy of Orlistat in Murine Hosts Bearing T Cell Lymphoma: Implication in Macrophage Differentiation and Activation

inferredcites →https://doi.org/10.1371/journal.pone.0097697openalex-snapshot

The mTOR Inhibitor Rapamycin Synergizes with a Fatty Acid Synthase Inhibitor to Induce Cytotoxicity in ER/HER2-Positive Breast Cancer Cells

inferredcites →https://doi.org/10.14670/hh-11-830openalex-snapshot

Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer.

inferredcites →https://doi.org/10.15252/emmm.201708313openalex-snapshot

Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non‐small cell lung cancer

inferredcites →https://doi.org/10.1667/rr13828.1openalex-snapshot

Energy Metabolism in a Matched Model of Radiation Resistance for Head and Neck Squamous Cell Cancer

inferredcites →https://doi.org/10.18632/oncotarget.25361openalex-snapshot

Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer

inferredcites →https://doi.org/10.18632/oncotarget.3783openalex-snapshot

Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration

inferredcites →https://doi.org/10.18632/oncotarget.6402openalex-snapshot

Implications of a peroxisome proliferator-activated receptor alpha (PPARα) ligand clofibrate in breast cancer

inferredcites →https://doi.org/10.2174/13816128113199990486openalex-snapshot

Targeting SREBP-1-driven Lipid Metabolism to Treat Cancer

inferredcites →https://doi.org/10.21873/anticanres.12083openalex-snapshot

Orlistat Reduces Proliferation and Enhances Apoptosis in Human Pancreatic Cancer Cells (PANC-1)

inferredcites →https://doi.org/10.21873/anticanres.13531openalex-snapshot

In Vivo Effectiveness of Orlistat in the Suppression of Human Colorectal Cancer Cell Proliferation

inferredcites →https://doi.org/10.2217/fon.10.11openalex-snapshot

Fatty Acid Synthase As a Potential Therapeutic Target in Cancer

inferredcites →https://doi.org/10.3389/fmolb.2019.00106openalex-snapshot

Fatty Acid Synthase Contributes to Restimulation-Induced Cell Death of Human CD4 T Cells

inferredcites →https://doi.org/10.3390/biom10040529openalex-snapshot

SUMOylation Protects FASN Against Proteasomal Degradation in Breast Cancer Cells Treated with Grape Leaf Extract

inferredcites →https://doi.org/10.3390/cells7030021openalex-snapshot

Elucidating the Metabolic Plasticity of Cancer: Mitochondrial Reprogramming and Hybrid Metabolic States

inferredcites →https://doi.org/10.3390/ijms19113434openalex-snapshot

Solute Carrier Family 27 Member 4 (SLC27A4) Enhances Cell Growth, Migration, and Invasion in Breast Cancer Cells

inferredcites →https://doi.org/10.3892/ijmm.2013.1602openalex-snapshot

Positive feedback regulation between Akt phosphorylation and fatty acid synthase expression in osteosarcoma

inferredcites →https://doi.org/10.3892/ijo.2013.1978openalex-snapshot

Enhanced antitumor activity of cerulenin combined with oxaliplatin in human colon cancer cells

inferredcites →https://doi.org/10.3892/ijo_00000455openalex-snapshot

Fatty acid synthase activity regulates HER2 extracellular domain shedding into the circulation of HER2-positive metastatic breast cancer patients

inferredcites →https://doi.org/10.3892/ol.2017.6954openalex-snapshot

Fatty acid synthase affects expression of ErbB receptors in epithelial to mesenchymal transition of breast cancer cells and invasive ductal carcinoma

inferredcites →https://doi.org/10.3892/ol.2018.7896openalex-snapshot

Inhibition of FASN expression enhances radiosensitivity in human non-small cell lung cancer

inferredcites →https://doi.org/10.3892/or.2016.4627openalex-snapshot

FASN, ErbB2-mediated glycolysis is required for breast cancer cell migration

inferredcites →https://doi.org/10.3892/or.2017.5519openalex-snapshot

MACC1 decreases the chemosensitivity of gastric cancer cells to oxaliplatin by regulating FASN expression

inferredcites →https://doi.org/10.4049/jimmunol.1601403openalex-snapshot

Adipose Fatty Acid Binding Protein Promotes Saturated Fatty Acid–Induced Macrophage Cell Death through Enhancing Ceramide Production

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inferredcites →https://doi.org/10.4161/cc.27767openalex-snapshot

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inferredcites →https://doi.org/10.4161/cc.29338openalex-snapshot

Involvement of de novo synthesized palmitate and mitochondrial EGFR in EGF induced mitochondrial fusion of cancer cells

inferredcites →https://doi.org/10.4161/cc.7.14.6475openalex-snapshot

Caveolin-1 interacts with a lipid raft-associated population of fatty acid synthase

inferredcites →https://doi.org/10.7150/ijms.29946openalex-snapshot

New Insight on Solute Carrier Family 27 Member 6 (SLC27A6) in Tumoral and Non-Tumoral Breast Cells

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1016/j.cellsig.2023.110903openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.cellsig.2025.111947openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.cmet.2022.09.023openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.coisb.2021.100401openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.ejca.2022.11.025openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.ejcb.2022.151225openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.ejphar.2021.174261openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.fct.2023.113986openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.fochms.2026.100387openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2022.03.002openalex-snapshot

TIGAR drives colorectal cancer ferroptosis resistance through ROS/AMPK/SCD1 pathway

inferred← citeshttps://doi.org/10.1016/j.gendis.2025.101521openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.gendis.2025.101817openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.gendis.2025.101873openalex-snapshot

Ferroptosis: The dawn of reversing drug resistance in digestive cancers

inferred← citeshttps://doi.org/10.1016/j.gene.2022.147023openalex-snapshot

Fatty acid synthase (FASN) inhibits the cervical squamous cell carcinoma (CESC) progression through the Akt/mTOR signaling pathway

inferred← citeshttps://doi.org/10.1016/j.genrep.2024.101936openalex-snapshot

A four-gene model for prognostic prediction in bladder urothelial carcinoma

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e30807openalex-snapshot

Targeting lipid reprogramming in the tumor microenvironment by traditional Chinese medicines as a potential cancer treatment

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e34029openalex-snapshot

Integrative analysis of Anoikis-related genes reveals that FASN is a novel prognostic biomarker and promotes the malignancy of bladder cancer via Wnt/β-catenin pathway

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.135792openalex-snapshot

RETRACTED: TPTEP1 impedes the reprogramming of fatty acid metabolism in triple negative breast cancer via miR-1343-3p/SIRT3 axis

inferred← citeshttps://doi.org/10.1016/j.impact.2025.100580openalex-snapshot

Microplastics impair wound healing via NAT10-mediated epigenetic dysregulation of FASN-PI3K/AKT signaling

inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113320openalex-snapshot

Palmitic acid inhibits macrophage-mediated chemotherapy resistance in multiple myeloma via ALOX12 signaling

inferred← citeshttps://doi.org/10.1016/j.jbc.2023.105344openalex-snapshot

On a sugar high: Role of O-GlcNAcylation in cancer

inferred← citeshttps://doi.org/10.1016/j.jddst.2023.104161openalex-snapshot

Nanocomposite zinc oxide@ γ-linolenic acid-canagliflozin-fucoxanthin and/or γ-radiation perturbs key metabolic effectors and suppresses the proliferation of breast cancer cells in vitro

inferred← citeshttps://doi.org/10.1016/j.jddst.2023.105086openalex-snapshot

Encapsulation of orlistat in biodegradable polymeric nanocapsules improves its cytotoxic effect against cervical cancer cells

inferred← citeshttps://doi.org/10.1016/j.jff.2021.104857openalex-snapshot

Momordica charantia leaf extract reduces hepatic lipid accumulation and diet-induced dyslipidemia in zebrafish through lipogenesis and beta-oxidation

inferred← citeshttps://doi.org/10.1016/j.jhep.2023.10.042openalex-snapshot

Pharmacologic inhibition of lipogenesis for the treatment of NAFLD

inferred← citeshttps://doi.org/10.1016/j.jlr.2026.100986openalex-snapshot

Kiss1-FASN participates fatty acid synthesis via high-fat diet in PgVAT of female mice

inferred← citeshttps://doi.org/10.1016/j.jlr.2026.100990openalex-snapshot

From damage signals to immune modulators: oxidized lipids in immunometabolic inflammation

inferred← citeshttps://doi.org/10.1016/j.jlr.2026.101038openalex-snapshot

Mammarenaviruses depend on endogenous fatty acid synthesis in cell culture systems

inferred← citeshttps://doi.org/10.1016/j.jlr.2026.101094openalex-snapshot

BK channel deficiency promotes lipolysis via an AKT-independent activation of the cAMP/PKA/HSL pathway

inferred← citeshttps://doi.org/10.1016/j.jprot.2022.104753openalex-snapshot

Applications of lipidomics in goat meat products: Biomarkers, structure, nutrition interface and future perspectives

inferred← citeshttps://doi.org/10.1016/j.mam.2022.101097openalex-snapshot

Pathological implication of protein post-translational modifications in cancer

inferred← citeshttps://doi.org/10.1016/j.metabol.2023.155679openalex-snapshot

Olfactomedin 4 deletion exacerbates nonalcoholic fatty liver disease through P62-dependent mitophagy in mice

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Pharmacologically targeting fatty acid synthase-mediated de novo lipogenesis alleviates osteolytic bone loss by directly inhibiting osteoclastogenesis through suppression of STAT3 palmitoylation and ROS signaling

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Screening of hepatoprotective natural products from Floccularia luteovirens via a novel HPLC-hepatocyte protein system combined with oil red O quantification strategy

inferred← citeshttps://doi.org/10.1016/j.molcel.2023.07.017openalex-snapshot

FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1

inferred← citeshttps://doi.org/10.1016/j.omtn.2022.02.010openalex-snapshot

Dysregulation of the miRNome unveils a crosstalk between obesity and prostate cancer: miR-107 asa personalized diagnostic and therapeutic tool

inferred← citeshttps://doi.org/10.1016/j.pharmthera.2022.108274openalex-snapshot

Interplay between fat cells and immune cells in bone: Impact on malignant progression and therapeutic response

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Characteristics of anticancer activity of CBP/p300 inhibitors – Features of their classes, intracellular targets and future perspectives of their application in cancer treatment

inferred← citeshttps://doi.org/10.1016/j.phymed.2025.156367openalex-snapshot

Melittin suppresses ovarian cancer growth by regulating SREBP1-mediated lipid metabolism

inferred← citeshttps://doi.org/10.1016/j.phymed.2025.157558openalex-snapshot

Huang-Jin-Shuang-Shen Decoction delays gastric tumorigenesis by suppressing stemness via SCD-mediated fatty acid metabolism modulation

inferred← citeshttps://doi.org/10.1016/j.plipres.2025.101354openalex-snapshot

Different chains for different gains: How acyl chain diversity shapes S-acylated protein function

inferred← citeshttps://doi.org/10.1016/j.prp.2023.154641openalex-snapshot

Sphingosine kinase 1 regulates lipid metabolism to promote progression of kidney renal clear cell carcinoma

inferred← citeshttps://doi.org/10.1016/j.prp.2026.156507openalex-snapshot

Therapeutic targeting of lipid metabolism in cancer: Mechanisms, pathways, and translational prospects

inferred← citeshttps://doi.org/10.1016/j.sajb.2024.10.053openalex-snapshot

Potato Protein Hydrolysate (PPH902) treatment in adipocytes inhibits lipogenesis by activating AMPK

inferred← citeshttps://doi.org/10.1016/j.semcancer.2024.12.002openalex-snapshot

Theoretical framework and emerging challenges of lipid metabolism in cancer

inferred← citeshttps://doi.org/10.1016/j.semcancer.2025.10.002openalex-snapshot

The emerging role of metabolic interventions in uveal melanoma

inferred← citeshttps://doi.org/10.1016/j.semcancer.2026.05.001openalex-snapshot

Systemic lipid metabolic alterations and the tumor microenvironment: A hidden driver of immune dysfunction

inferred← citeshttps://doi.org/10.1016/j.tips.2024.04.007openalex-snapshot

Emerging targets in lipid metabolism for cancer therapy

inferred← citeshttps://doi.org/10.1016/j.tranon.2025.102396openalex-snapshot

Targeting FASN enhances cisplatin sensitivity via SLC7A11-mediated ferroptosis in cervical cancer

inferred← citeshttps://doi.org/10.1016/j.xcrm.2024.101525openalex-snapshot

α2δ1-mediated maladaptive sensory plasticity disrupts adipose tissue homeostasis following spinal cord injury

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.4c02809openalex-snapshot

A Collection of Novel Antitumor Agents That Regulate Lipid Metabolism in the Tumor Microenvironment

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5c02527openalex-snapshot

Novel Resorcinol Dibenzyl Ether-Based PD-L1 Inhibitors Modulate Lipid Metabolism for Enhanced Tumor Immunotherapy

inferred← citeshttps://doi.org/10.1021/acs.jproteome.2c00646openalex-snapshot

Integrative Proteomic and Pharmacological Analysis of Colon Cancer Reveals the Classical Lipogenic Pathway with Prognostic and Therapeutic Opportunities

inferred← citeshttps://doi.org/10.1021/acs.jproteome.6c00246openalex-snapshot

Proteomic Signatures of Vemurafenib Resistance in Canine Urothelial Carcinoma Harboring the BRAFV595E Mutation

inferred← citeshttps://doi.org/10.1021/acsomega.6c01688openalex-snapshot

Synergistic Targeting of Geranylgeranyl Diphosphate Synthase and Fatty Acid Synthase for Multiple Myeloma

inferred← citeshttps://doi.org/10.1021/acsptsci.3c00182openalex-snapshot

Fatty Acid Synthase Inhibitors Enhance Microtubule-Stabilizing and Microtubule-Destabilizing Drugs in Taxane-Resistant Prostate Cancer Cells

inferred← citeshttps://doi.org/10.1021/acsptsci.4c00545openalex-snapshot

Harnessing Drug Repurposing to Combat Breast Cancer by Targeting Altered Metabolism and Epithelial-to-Mesenchymal Transition Pathways

inferred← citeshttps://doi.org/10.1038/s12276-023-01020-1openalex-snapshot

Metabolic reprogramming and epigenetic modifications in cancer: from the impacts and mechanisms to the treatment potential

inferred← citeshttps://doi.org/10.1038/s12276-026-01697-0openalex-snapshot

Metabolic networks in the tumor microenvironment: roles of amino acid and lipid metabolism pathways in cancer progression and therapy

inferred← citeshttps://doi.org/10.1038/s41375-023-02130-5openalex-snapshot

Targeting ZDHHC21/FASN axis for the treatment of diffuse large B-cell lymphoma

inferred← citeshttps://doi.org/10.1038/s41389-022-00420-8openalex-snapshot

Lipids in cancer: a global view of the contribution of lipid pathways to metastatic formation and treatment resistance

inferred← citeshttps://doi.org/10.1038/s41418-023-01223-zopenalex-snapshot

CDK13 promotes lipid deposition and prostate cancer progression by stimulating NSUN5-mediated m5C modification of ACC1 mRNA

inferred← citeshttps://doi.org/10.1038/s41419-021-04262-xopenalex-snapshot

Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells

inferred← citeshttps://doi.org/10.1038/s41419-021-04411-2openalex-snapshot

SLC25A1 promotes tumor growth and survival by reprogramming energy metabolism in colorectal cancer

inferred← citeshttps://doi.org/10.1038/s41419-024-06463-6openalex-snapshot

The implications of FASN in immune cell biology and related diseases

inferred← citeshttps://doi.org/10.1038/s41420-024-02126-9openalex-snapshot

Fatty acid metabolism-related enzymes in colorectal cancer metastasis: from biological function to molecular mechanism

inferred← citeshttps://doi.org/10.1038/s41420-025-02409-9openalex-snapshot

FASN promotes lipid metabolism and progression in colorectal cancer via the SP1/PLA2G4B axis

inferred← citeshttps://doi.org/10.1038/s41420-025-02480-2openalex-snapshot

C12ORF49 inhibits ferroptosis in hepatocellular carcinoma cells via reprogramming SREBP1/SCD1-mediated lipid metabolism

inferred← citeshttps://doi.org/10.1038/s41420-025-02814-0openalex-snapshot

hnRNP A1 inhibits colorectal cancer tumorigenesis and progression by regulating fatty acid metabolism and RNA stability

inferred← citeshttps://doi.org/10.1038/s41467-023-39266-yopenalex-snapshot

Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat

inferred← citeshttps://doi.org/10.1038/s41467-024-46696-9openalex-snapshot

A fast-acting lipid checkpoint in G1 prevents mitotic defects

inferred← citeshttps://doi.org/10.1038/s41467-024-54400-0openalex-snapshot

High mobility group A1 (HMGA1) promotes the tumorigenesis of colorectal cancer by increasing lipid synthesis

inferred← citeshttps://doi.org/10.1038/s41556-023-01198-6openalex-snapshot

Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor

inferred← citeshttps://doi.org/10.1038/s41556-023-01206-9openalex-snapshot

Malonyl-CoA links lipid metabolism to nutrient signalling by directly inhibiting mTORC1

inferred← citeshttps://doi.org/10.1038/s41573-021-00367-2openalex-snapshot

Lipogenesis inhibitors: therapeutic opportunities and challenges

inferred← citeshttps://doi.org/10.1038/s41598-022-25356-2openalex-snapshot

A six lipid metabolism related gene signature for predicting the prognosis of hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1038/s41598-023-44753-9openalex-snapshot

Impact of trifluoromethyl and sulfonyl groups on the biological activity of novel aryl-urea derivatives: synthesis, in-vitro, in-silico and SAR studies

inferred← citeshttps://doi.org/10.1038/s41598-023-48485-8openalex-snapshot

Periostin facilitates ovarian cancer recurrence by enhancing cancer stemness

inferred← citeshttps://doi.org/10.1038/s41598-024-62917-zopenalex-snapshot

A novel fatty acid metabolism-related signature identifies MUC4 as a novel therapy target for esophageal squamous cell carcinoma

inferred← citeshttps://doi.org/10.1038/s41598-025-24547-xopenalex-snapshot

The cyclic peptide mallotumide A inhibits colon and breast cancer cell growth and motility by targeting cellular respiration and lipogenesis

inferred← citeshttps://doi.org/10.1038/s41598-025-30376-9openalex-snapshot

A novel angiogenesis-related gene signature predicting prognosis in clear cell renal cell carcinoma

inferred← citeshttps://doi.org/10.1038/s42003-025-07656-1openalex-snapshot

Targeting fatty acid synthase reduces aortic atherosclerosis and inflammation

inferred← citeshttps://doi.org/10.1038/s42003-025-09020-9openalex-snapshot

Acetyl-CoA carboxylase 1 knockdown promotes esophageal squamous cell carcinoma metastasis via the CXCL8–NET axis

inferred← citeshttps://doi.org/10.1038/s42255-023-00873-0openalex-snapshot

A defect in mitochondrial fatty acid synthesis impairs iron metabolism and causes elevated ceramide levels

inferred← citeshttps://doi.org/10.1038/s44276-025-00134-5openalex-snapshot

Metabolic reprogramming in glioblastoma: a rare case of recurrence to scalp metastasis

inferred← citeshttps://doi.org/10.1042/bsr20222496openalex-snapshot

Kinetic data for modeling the dynamics of the enzymes involved in animal fatty acid synthesis

inferred← citeshttps://doi.org/10.1055/a-2229-3489openalex-snapshot

Serum Lipid Level in Evaluating Chinese Pancreatic Neuroendocrine Neoplasms: A Retrospective Study

inferred← citeshttps://doi.org/10.1055/s-0041-1731709openalex-snapshot

Role of Lipogenesis Rewiring in Hepatocellular Carcinoma.

inferred← citeshttps://doi.org/10.1055/s-0043-1768477openalex-snapshot

In Vivo and in Silico Assessment of Ameliorative Effects of Xylopia aethiopica on Testosterone Propionate-Induced Benign Prostatic Hyperplasia

inferred← citeshttps://doi.org/10.1055/s-0043-1772607openalex-snapshot

Buchholzia coriacea Leaves Attenuated Dyslipidemia and Oxidative Stress in Hyperlipidemic Rats and Its Potential Targets In Silico

inferred← citeshttps://doi.org/10.1080/00498254.2026.2680076openalex-snapshot

Lipid dysregulation in chronic diseases: systems biology and omics perspectives

inferred← citeshttps://doi.org/10.1080/01635581.2022.2108467openalex-snapshot

Proton Pump Inhibitor Use and Obesity-Associated Cancer in the Women’s Health Initiative

inferred← citeshttps://doi.org/10.1080/07391102.2023.2273441openalex-snapshot

Computational study on natural molecules targeting β-ketoacyl reductase domain of fatty acid synthase for the identification of selective inhibitors

inferred← citeshttps://doi.org/10.1080/13543776.2023.2291393openalex-snapshot

SREBP inhibitors: an updated patent review for 2008-present

inferred← citeshttps://doi.org/10.1080/13543784.2024.2313091openalex-snapshot

The impact of current investigational drugs for acne on future treatment strategies

inferred← citeshttps://doi.org/10.1080/15384047.2024.2403197openalex-snapshot

FASN contributes to ADM resistance of diffuse large B-cell lymphoma by inhibiting ferroptosis via nf-κB/STAT3/GPX4 axis

inferred← citeshttps://doi.org/10.1093/bib/bbae365openalex-snapshot

GloEC: a hierarchical-aware global model for predicting enzyme function

inferred← citeshttps://doi.org/10.1093/g3journal/jkag182openalex-snapshot

Loss of ptr-6 restores eggshell integrity and embryonic viability in Caenorhabditis elegans fatty acid synthase mutants

inferred← citeshttps://doi.org/10.1093/jrr/rrac037openalex-snapshot

Proteomic and miRNA profiling of radon-induced skin damage in mice: FASN regulated by miRNAs

inferred← citeshttps://doi.org/10.1097/cm9.0000000000002880openalex-snapshot

Regulation of fatty acid synthase on tumor and progress in the development of related therapies

inferred← citeshttps://doi.org/10.1097/md.0000000000032542openalex-snapshot

Development of fatty acid metabolism-related models in lung adenocarcinomaA Review

inferred← citeshttps://doi.org/10.1097/md.0000000000037824openalex-snapshot

Identification of two distinct head and neck squamous cell carcinoma subtypes based on fatty acid metabolism-related signatures: Implications for immunotherapy and chemotherapy

inferred← citeshttps://doi.org/10.1097/ot9.0000000000000132openalex-snapshot

Medicinal plants with antineoplastic potency and possible biomarkers for monitoring and diagnosing neoplastic disease

inferred← citeshttps://doi.org/10.1101/2021.03.12.435005openalex-snapshot

Molecular Response to PARP1 Inhibition in Ovarian Cancer Cells as Determined by Mass Spectrometry Based Proteomics

inferred← citeshttps://doi.org/10.1101/2022.11.06.515351openalex-snapshot

Malonyl-CoA is an ancient physiological ATP-competitive mTORC1 inhibitor

inferred← citeshttps://doi.org/10.1101/2023.03.10.23287084openalex-snapshot

Identifying metabolic features of colorectal cancer liability using Mendelian randomization

inferred← citeshttps://doi.org/10.1101/2023.04.14.536458openalex-snapshot

Loss of Mitochondrial Enoyl CoA Reductase causes elevated ceramide levels and impairs iron metabolism

inferred← citeshttps://doi.org/10.1101/2023.05.17.541082openalex-snapshot

Subchronic Toxicity Assessment of Perfluoroalkyl Substances by Mixed Exposure of Nine Substances at Daily Intake Relevant Concentration

inferred← citeshttps://doi.org/10.1101/2024.12.18.628624openalex-snapshot

Targeting de novo lipogenesis improves gemcitabine efficacy in pancreatic ductal adenocarcinoma

inferred← citeshttps://doi.org/10.1101/2025.07.16.662511openalex-snapshot

Fatty Acid Synthase associates with nuclear-derived cytoplasmic dsRNA molecules and influences antiviral innate immune response

inferred← citeshttps://doi.org/10.1111/1541-4337.70307openalex-snapshot

Gut Microbiota and Lipid Metabolism: Impacts on Lamb Flavor Precursors

inferred← citeshttps://doi.org/10.1111/1744-7917.70032openalex-snapshot

Dimm targets GDAP2 to regulate larval development in the silkworm, Bombyx mori

inferred← citeshttps://doi.org/10.1111/cbdd.13942openalex-snapshot

Review on target domains and natural compound‐based inhibitors of fatty acid synthase for anticancer drug discovery

inferred← citeshttps://doi.org/10.1111/cbdd.14138openalex-snapshot

Classification analysis of fatty acid synthase inhibitors using multialgorithms on topological descriptors and structural fingerprints

inferred← citeshttps://doi.org/10.1111/imb.12877openalex-snapshot

The influence of first desaturase subfamily genes on fatty acid synthesis, desiccation tolerance and inter‐caste nutrient transfer in the termite Coptotermes formosanus

inferred← citeshttps://doi.org/10.1111/imm.13871openalex-snapshot

Metabolic Reprogramming in Cancer: Implications for Immunosuppressive Microenvironment

inferred← citeshttps://doi.org/10.1111/jgh.16879openalex-snapshot

Clonorchis sinensis Promotes Intrahepatic Cholangiocarcinoma Progression by Activating FASN‐Mediated Fatty Acid Metabolism

inferred← citeshttps://doi.org/10.1111/jgh.70165openalex-snapshot

Narirutin Reprograms Fatty Acid Metabolism and Inhibits Tumorigenesis via Downregulating ADORA3 Expression in Colorectal Cancer

inferred← citeshttps://doi.org/10.1111/jocd.16567openalex-snapshot

Exploring Genetic Drug Targets in Acne Vulgaris: A Comprehensive Proteome‐Wide Mendelian Randomization Study

inferred← citeshttps://doi.org/10.1126/scisignal.aay1027openalex-snapshot

Fibrometabolism—An emerging therapeutic frontier in pulmonary fibrosis

inferred← citeshttps://doi.org/10.1128/mbio.02176-25openalex-snapshot

Transcriptional responses of mouse proximal colon and colonoids during early whipworm infection

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