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Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non‐small cell lung cancer
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1097-0142(19960201)77:3<474::aid-cncr8>3.0.co;2-kopenalex-snapshot
Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage I breast carcinoma patients
inferredcites →https://doi.org/10.1002/ijc.23835openalex-snapshot
Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model
inferredcites →https://doi.org/10.1002/pros.23796openalex-snapshot
Dietary palmitate cooperates with Src kinase to promote prostate tumor progression
inferredcites →https://doi.org/10.1016/j.bbamem.2011.07.009openalex-snapshot
Protein palmitoylation and subcellular trafficking
inferredcites →https://doi.org/10.1016/j.bbrc.2013.04.001openalex-snapshot
Ubiquitination and degradation of the hominoid-specific oncoprotein TBC1D3 is regulated by protein palmitoylation
inferredcites →https://doi.org/10.1016/j.ccr.2006.12.017openalex-snapshot
Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity
inferredcites →https://doi.org/10.1016/j.ccr.2007.06.005openalex-snapshot
Bronchial and Peripheral Murine Lung Carcinomas Induced by T790M-L858R Mutant EGFR Respond to HKI-272 and Rapamycin Combination Therapy
inferredcites →https://doi.org/10.1016/j.ccr.2010.01.022openalex-snapshot
A Transcriptional Signature and Common Gene Networks Link Cancer with Lipid Metabolism and Diverse Human Diseases
inferredcites →https://doi.org/10.1016/j.ccr.2012.02.014openalex-snapshot
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
inferredcites →https://doi.org/10.1016/j.cell.2011.02.013openalex-snapshot
Hallmarks of Cancer: The Next Generation
inferredcites →https://doi.org/10.1016/j.cmet.2013.08.002openalex-snapshot
A Central Role for mTOR in Lipid Homeostasis
inferredcites →https://doi.org/10.1016/j.cub.2009.09.058openalex-snapshot
An Emerging Role of mTOR in Lipid Biosynthesis
inferredcites →https://doi.org/10.1016/j.gde.2009.11.002openalex-snapshot
Targeting the PI3K signaling pathway in cancer
inferredcites →https://doi.org/10.1016/j.juro.2008.04.135openalex-snapshot
Fatty Acid Synthase Over Expression is an Indicator of Tumor Aggressiveness and Poor Prognosis in Renal Cell Carcinoma
inferredcites →https://doi.org/10.1016/j.lungcan.2008.05.017openalex-snapshot
Epithelial to mesenchymal transition derived from repeated exposure to gefitinib determines the sensitivity to EGFR inhibitors in A549, a non-small cell lung cancer cell line
inferredcites →https://doi.org/10.1016/j.molcel.2016.04.003openalex-snapshot
Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling
inferredcites →https://doi.org/10.1016/j.plipres.2016.05.002openalex-snapshot
Fatty acylation of proteins: The long and the short of it
inferredcites →https://doi.org/10.1016/s0046-8177(97)90177-5openalex-snapshot
Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival
inferredcites →https://doi.org/10.1016/s0899-9007(99)00266-xopenalex-snapshot
Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology
inferredcites →https://doi.org/10.1021/bi802249xopenalex-snapshot
Palmitoylation of the EGF Receptor Impairs Signal Transduction and Abolishes High-Affinity Ligand Binding
inferredcites →https://doi.org/10.1021/jacs.5b02326openalex-snapshot
Structural Differences between Wild-Type and Double Mutant EGFR Modulated by Third-Generation Kinase Inhibitors
inferredcites →https://doi.org/10.1038/labinvest.2008.97openalex-snapshot
Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of β-catenin in prostate cancer
inferredcites →https://doi.org/10.1038/labinvest.2010.157openalex-snapshot
Inhibition of fatty acid synthase in melanoma cells activates the intrinsic pathway of apoptosis
inferredcites →https://doi.org/10.1038/nprot.2007.225openalex-snapshot
Palmitoylated proteins: purification and identification
inferredcites →https://doi.org/10.1038/nprot.2011.424openalex-snapshot
Quantitative monitoring of mouse lung tumors by magnetic resonance imaging
inferredcites →https://doi.org/10.1038/nrc2222openalex-snapshot
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
inferredcites →https://doi.org/10.1038/nrm2084openalex-snapshot
Palmitoylation: policing protein stability and traffic
inferredcites →https://doi.org/10.1038/nsmb1265openalex-snapshot
Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat
inferredcites →https://doi.org/10.1038/sj.emboj.7600724openalex-snapshot
Swf1‐dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation
inferredcites →https://doi.org/10.1038/sj.embor.7400006openalex-snapshot
Basolateral targeting by leucine-rich repeat domains in epithelial cells
inferredcites →https://doi.org/10.1053/hupa.2000.9842openalex-snapshot
The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung
inferredcites →https://doi.org/10.1056/nejmoa044238openalex-snapshot
EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib
inferredcites →https://doi.org/10.1073/pnas.0709662105openalex-snapshot
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
inferredcites →https://doi.org/10.1073/pnas.091062498openalex-snapshot
Significance analysis of microarrays applied to the ionizing radiation response
inferredcites →https://doi.org/10.1074/jbc.275.16.11858openalex-snapshot
Conditional Expression of Fibroblast Growth Factor-7 in the Developing and Mature Lung
inferredcites →https://doi.org/10.1074/jbc.m405061200openalex-snapshot
A Fatty Acid Synthase Blockade Induces Tumor Cell-cycle Arrest by Down-regulating Skp2
inferredcites →https://doi.org/10.1083/jcb.200610151openalex-snapshot
Palmitoylation-dependent protein sorting
inferredcites →https://doi.org/10.1093/jnci/djp030openalex-snapshot
Fatty Acid Synthase: A Metabolic Enzyme and Candidate Oncogene in Prostate Cancer
inferredcites →https://doi.org/10.1093/nar/gkr1013openalex-snapshot
PrimerBank: a PCR primer database for quantitative gene expression analysis, 2012 update
inferredcites →https://doi.org/10.1101/gad.1417406openalex-snapshot
Lung adenocarcinomas induced in mice by mutant EGF receptors foundin human lung cancers respondto a tyrosine kinase inhibitor orto down-regulation of the receptors
inferredcites →https://doi.org/10.1111/febs.12263openalex-snapshot
What does S ‐palmitoylation do to membrane proteins?
inferredcites →https://doi.org/10.1111/j.1600-0854.2008.00814.xopenalex-snapshot
Palmitoylation Controls Recycling in Lysosomal Sorting and Trafficking
inferredcites →https://doi.org/10.1111/j.1742-4658.2012.08644.xopenalex-snapshot
Lipid metabolism in cancer
inferredcites →https://doi.org/10.1126/scisignal.2000446openalex-snapshot
EGFR Signaling Through an Akt-SREBP-1–Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy
inferredcites →https://doi.org/10.1126/scitranslmed.3002003openalex-snapshot
Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors
inferredcites →https://doi.org/10.1158/0008-5472.can-03-3645openalex-snapshot
Orlistat Is a Novel Inhibitor of Fatty Acid Synthase with Antitumor Activity
inferredcites →https://doi.org/10.1158/0008-5472.can-07-0681openalex-snapshot
Emergence of Epidermal Growth Factor Receptor T790M Mutation during Chronic Exposure to Gefitinib in a Non–Small Cell Lung Cancer Cell Line
inferredcites →https://doi.org/10.1158/0008-5472.can-11-0885openalex-snapshot
Aberrant Lipid Metabolism in Hepatocellular Carcinoma Revealed by Plasma Metabolomics and Lipid Profiling
inferredcites →https://doi.org/10.1158/1078-0432.ccr-03-0564openalex-snapshot
United States Food and Drug Administration Drug Approval Summary
inferredcites →https://doi.org/10.1158/1535-7163.mct-07-0445openalex-snapshot
A new mechanism of drug resistance in breast cancer cells: fatty acid synthase overexpression-mediated palmitate overproduction
inferredcites →https://doi.org/10.1158/1535-7163.mct-12-1136openalex-snapshot
The Fatty Acid Synthase Inhibitor Orlistat Reduces the Growth and Metastasis of Orthotopic Tongue Oral Squamous Cell Carcinomas
inferredcites →https://doi.org/10.1158/2159-8290.cd-19-0061openalex-snapshot
Glioma Stem Cell–Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling
inferredcites →https://doi.org/10.1172/jci0215593openalex-snapshot
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
inferredcites →https://doi.org/10.1172/jci15593openalex-snapshot
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
inferredcites →https://doi.org/10.1186/1756-0500-7-157openalex-snapshot
In silico prediction of protein-protein interactions in human macrophages
inferredcites →https://doi.org/10.1186/s13046-019-1120-4openalex-snapshot
Co-administration of 20(S)-protopanaxatriol (g-PPT) and EGFR-TKI overcomes EGFR-TKI resistance by decreasing SCD1 induced lipid accumulation in non-small cell lung cancer
inferredcites →https://doi.org/10.1200/jco.2008.18.2675openalex-snapshot
Cohort Study of Fatty Acid Synthase Expression and Patient Survival in Colon Cancer
inferredcites →https://doi.org/10.18632/oncotarget.5252openalex-snapshot
Intracellular activation of EGFR by fatty acid synthase dependent palmitoylation
inferredcites →https://doi.org/10.18632/oncotarget.8706openalex-snapshot
Palmitoylation regulates the intracellular trafficking and stability of c-Met
inferredcites →https://doi.org/10.7150/thno.35805openalex-snapshot
CAV1 - GLUT3 signaling is important for cellular energy and can be targeted by Atorvastatin in Non-Small Cell Lung Cancer
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Fatty Acid Synthesis Is Indispensable for Survival of Human Pluripotent Stem Cells
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ZDHHC13 Is a Catalytically Deficient Protein S -Acyltransferase That Functions via a Noncanonical Mechanism
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Targeting ZDHHC21/FASN axis for the treatment of diffuse large B-cell lymphoma
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Involvement of the pro-oncogenic enzyme fatty acid synthase in the hallmarks of cancer: a promising target in anti-cancer therapies
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Signaling pathways of chronic kidney diseases, implications for therapeutics
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FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth
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PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway
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ZDHHC1 downregulates LIPG and inhibits colorectal cancer growth via IGF2BP1 Palmitoylation
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Sulforaphane downregulated fatty acid synthase and inhibited microtubule-mediated mitophagy leading to apoptosis
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Non-alcoholic fatty liver disease promotes liver metastasis of colorectal cancer via fatty acid synthase dependent EGFR palmitoylation
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Fatty acid synthase (FASN) is a tumor-cell-intrinsic metabolic checkpoint restricting T-cell immunity
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Role of S-palmitoylation in digestive system diseases
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Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system
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PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma
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Protein lipidation in cancer: mechanisms, dysregulation and emerging drug targets
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Plasma metabolomics profiling of EGFR-mutant NSCLC patients treated with third-generation EGFR-TKI
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Identification and immune landscape analysis of fatty acid metabolism genes related subtypes of gastric cancer
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Restoration of Osimertinib sensitivity in lung cancer through BRD4 inhibitor-mediated depalmitoylation of mutant EGFR via APT1
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Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer
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Therapeutic targeting of protein S-acylation for the treatment of disease
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Lipids regulate epidermal growth factor receptor activation by its ligands
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Protein lipidation in cardiovascular homeostasis, development, and disease
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The molecular era of protein S-acylation: spotlight on structure, mechanisms, and dynamics
inferred← citeshttps://doi.org/10.1080/14728222.2023.2255377openalex-snapshot
Lipid metabolism in malignant tumor brain metastasis: reprogramming and therapeutic potential
inferred← citeshttps://doi.org/10.1083/jcb.202307103openalex-snapshot
Refining S-acylation: Structure, regulation, dynamics, and therapeutic implications
inferred← citeshttps://doi.org/10.1093/toxres/tfag065openalex-snapshot
Integrated network toxicology and bioinformatics predict potential PFAS-mediated molecular mechanisms underlying colorectal cancer: in silico insights from transcriptome analysis, machine learning and molecular dynamics simulation
inferred← citeshttps://doi.org/10.1097/cm9.0000000000004016openalex-snapshot
Epidermal growth factor receptor tyrosine kinase inhibitor for the treatment of non-small cell lung cancer in the past 30 years (1997–2026)
inferred← citeshttps://doi.org/10.1098/rsob.200415openalex-snapshot
A novel yeast-based high-throughput method for the identification of protein palmitoylation inhibitors
inferred← citeshttps://doi.org/10.1101/2024.02.10.579759openalex-snapshot
Identification of key genes and biological pathways in chronic obstructive pulmonary disease using bioinformatics and next generation sequencing data analysis
inferred← citeshttps://doi.org/10.1101/2025.06.27.661913openalex-snapshot
Reprogramming of Osimertinib-Resistant EGFR-mutant NSCLC: The Pyruvate-Acetaldehyde-Acetate Pathway As a Key Driver of Resistance
inferred← citeshttps://doi.org/10.1111/boc.202100052openalex-snapshot
How palmitoylation affects trafficking and signaling of membrane receptors
inferred← citeshttps://doi.org/10.1111/cas.16085openalex-snapshot
Inhibition of palmitoyltransferase ZDHHC12 sensitizes ovarian cancer cells to cisplatin through ROS ‐mediated mechanisms
inferred← citeshttps://doi.org/10.1111/jop.13235openalex-snapshot
Fatty acid synthase mediates high glucose‐induced EGFR activation in oral dysplastic keratinocytes
inferred← citeshttps://doi.org/10.1124/pharmrev.123.000906openalex-snapshot
Targeting Epidermal Growth Factor Receptor for Cancer Treatment: Abolishing Both Kinase-Dependent and Kinase-Independent Functions of the Receptor
inferred← citeshttps://doi.org/10.1128/mbio.03954-24openalex-snapshot
Mammalian fatty acid synthase: a commonly used viral host dependency factor and a putative target for host-targeted broad-spectrum antiviral therapeutic development
inferred← citeshttps://doi.org/10.1158/0008-5472.c.6514344.v1openalex-snapshot
Data from Elevated Methionine Flux Drives Pyroptosis Evasion in Persister Cancer Cells
inferred← citeshttps://doi.org/10.1158/0008-5472.can-22-1002openalex-snapshot
Elevated Methionine Flux Drives Pyroptosis Evasion in Persister Cancer Cells
inferred← citeshttps://doi.org/10.1158/0008-5472.can-22-3105openalex-snapshot
ZDHHC2-Mediated AGK Palmitoylation Activates AKT–mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma
inferred← citeshttps://doi.org/10.1158/0008-5472.can-23-2266openalex-snapshot
PRMT1 Sustains De Novo Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-Negative Breast Cancer
inferred← citeshttps://doi.org/10.1158/2159-8290.cd-19-0061openalex-snapshot
Glioma Stem Cell–Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling
inferred← citeshttps://doi.org/10.1158/2767-9764.crc-23-0161openalex-snapshot
Tumor Microenvironment Landscapes Supporting EGFR-mutant NSCLC Are Modulated at the Single-cell Interaction Level by Unesbulin Treatment
inferred← citeshttps://doi.org/10.11817/j.issn.1672-7347.2021.200529openalex-snapshot
Role of metabolic reprogramming in drug resistance to epidermal growth factor tyrosine kinase inhibitors in non-small cell lung cancer.
inferred← citeshttps://doi.org/10.1186/s12885-022-10062-zopenalex-snapshot
An IGF-1R-mTORC1-SRPK2 signaling Axis contributes to FASN regulation in breast cancer
inferred← citeshttps://doi.org/10.1186/s12943-024-02165-xopenalex-snapshot
Metabolic reprogramming and therapeutic resistance in primary and metastatic breast cancer
inferred← citeshttps://doi.org/10.1186/s12957-023-03223-2openalex-snapshot
Missense variants in CYP4B1 associated with increased risk of lung cancer among Chinese Han population
inferred← citeshttps://doi.org/10.1186/s12964-023-01129-wopenalex-snapshot
The role of tumor microenvironment on cancer stem cell fate in solid tumors
inferred← citeshttps://doi.org/10.1186/s12964-025-02398-3openalex-snapshot
Lipid overload meets S-palmitoylation: a metabolic signalling nexus driving cardiovascular and heart disease
inferred← citeshttps://doi.org/10.1186/s13045-022-01349-6openalex-snapshot
TGF-β signaling in the tumor metabolic microenvironment and targeted therapies
inferred← citeshttps://doi.org/10.1186/s13045-023-01498-2openalex-snapshot
Lipid metabolic reprogramming in tumor microenvironment: from mechanisms to therapeutics
inferred← citeshttps://doi.org/10.1186/s13045-025-01738-7openalex-snapshot
Recent advances in S-palmitoylation and its emerging roles in human diseases
inferred← citeshttps://doi.org/10.1186/s13046-018-0784-5openalex-snapshot
Emerging role of lipid metabolism alterations in Cancer stem cells
inferred← citeshttps://doi.org/10.1186/s13046-019-1120-4openalex-snapshot
Co-administration of 20(S)-protopanaxatriol (g-PPT) and EGFR-TKI overcomes EGFR-TKI resistance by decreasing SCD1 induced lipid accumulation in non-small cell lung cancer
inferred← citeshttps://doi.org/10.1186/s13046-026-03748-wopenalex-snapshot
Mesenchymal stem cell-induced metabolic reprogramming of EGFR-wild-type tumor cells drives therapeutic resistance in EGFR-mutant non-small cell lung cancer
inferred← citeshttps://doi.org/10.1186/s40360-026-01087-2openalex-snapshot
Compound 7 h exerts its anti-oncogenic effects on colorectal cancer cells by inducing death-receptor-mediated apoptosis, promoting DNA damage, and obstructing autophagic flux
inferred← citeshttps://doi.org/10.1360/ssv-2025-0271openalex-snapshot
Targeting the Achilles’ heel of cancer stem cells
inferred← citeshttps://doi.org/10.15252/embr.201846666openalex-snapshot
Protein palmitoylation and cancer
inferred← citeshttps://doi.org/10.1590/0001-3765202220210670openalex-snapshot
Fatty acid synthase as a potential new therapeutic target for cervical cancer
inferred← citeshttps://doi.org/10.20517/cdr.2025.231openalex-snapshot
From EGFR PTM network to TKI resistance: spatial subtypes and targeting in lung cancer
inferred← citeshttps://doi.org/10.20517/jca.2022.29openalex-snapshot
The TNNI3 p.R186Q mutation is responsible for hypertrophic cardiomyopathy via promoting FASN-stimulated abnormal fatty acid metabolism
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1555764/v1openalex-snapshot
An IGF-1R-mTORC1-SRPK2 Signaling Axis Contributes to FASN Regulation in Breast Cancer
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2713906/v1openalex-snapshot
Novel molecular subtype-based precision therapy improves prognosis for lung adenocarcinoma patients
inferred← citeshttps://doi.org/10.21203/rs.3.rs-4015043/v1openalex-snapshot
Inhibition of fatty acid synthase in fibroblasts alleviates pulmonary fibrosis through the regulation of β- catenin
inferred← citeshttps://doi.org/10.21203/rs.3.rs-4378198/v1openalex-snapshot
A retrospective study of the efficacy and safety of Almonertinib in the treatment of locally advanced or brain metastatic non-small cell lung cancer with EGFR-positive mutations
inferred← citeshttps://doi.org/10.21203/rs.3.rs-4648786/v1openalex-snapshot
Functional role of fatty acid synthase for signal transduction in Core binding factor-AML with activating c-Kit mutation
inferred← citeshttps://doi.org/10.21203/rs.3.rs-7522725/v1openalex-snapshot
Omics-Assisted Biomarkers Identification and Docking-Based Therapeutic Exploration of Moringa Phytoconstituents in Chronic Obstructive Pulmonary Disease
inferred← citeshttps://doi.org/10.2147/jir.s284279openalex-snapshot
Diallyl Sulfide-Mediated Modulation of the Fatty Acid Synthase (FASN) Leads to Cancer Cell Death in BaP-Induced Lung Carcinogenesis in Swiss Mice
inferred← citeshttps://doi.org/10.2147/lctt.s512936openalex-snapshot
Elucidating the Role of FASN in Lung Cancer Stem Cells in Sensitive and Resistant EGFR-Mutated Non-Small Cell Lung Cancer Cells
inferred← citeshttps://doi.org/10.2217/epi-2021-0229openalex-snapshot
MiR-421 Promotes Lipid Metabolism by Targeting PTEN Via Activating PI3K/AKT/mTOR Pathway in Non-Small Cell Lung Cancer
inferred← citeshttps://doi.org/10.24976/discov.med.202436183.78openalex-snapshot
Gefitinib Induces Apoptosis in NSCLC Cells by Promoting Glutaminolysis and Inhibiting the MEK/ERK Signaling Pathway
inferred← citeshttps://doi.org/10.32604/or.2024.054623openalex-snapshot
Immunomodulatory behavior of CircRNAs in tumor microenvironment
inferred← citeshttps://doi.org/10.3389/fcell.2021.734897openalex-snapshot
Potential Role of S-Palmitoylation in Cancer Stem Cells of Lung Adenocarcinoma
inferred← citeshttps://doi.org/10.3389/fcell.2022.875318openalex-snapshot
Novel Insights on Lipid Metabolism Alterations in Drug Resistance in Cancer
inferred← citeshttps://doi.org/10.3389/fcell.2024.1399065openalex-snapshot
Unraveling the intricate relationship between lipid metabolism and oncogenic signaling pathways
inferred← citeshttps://doi.org/10.3389/fcell.2026.1802109openalex-snapshot
Bridging metabolic reprogramming and targeted therapy: the critical role of S-palmitoylation in cancer
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1640016openalex-snapshot
Palmitoylation in cancer: decoding its roles in signal transduction, tumor immunity, and emerging therapeutic opportunities
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1696102openalex-snapshot
Bidirectional regulation of lipid metabolism and the tumor microenvironment: new perspectives from mechanism to therapy
inferred← citeshttps://doi.org/10.3389/fmed.2025.1680118openalex-snapshot
The burden of interstitial lung disease and pulmonary sarcoidosis lung cancer among adolescents and young adults from 1990 to 2021 and its projections: a comparative study between China and other G20 countries
inferred← citeshttps://doi.org/10.3389/fmmed.2022.1044585openalex-snapshot
Acetyl-CoA: An interplay between metabolism and epigenetics in cancer
inferred← citeshttps://doi.org/10.3389/fonc.2020.01025openalex-snapshot
KDM5C Represses FASN-Mediated Lipid Metabolism to Exert Tumor Suppressor Activity in Intrahepatic Cholangiocarcinoma
inferred← citeshttps://doi.org/10.3389/fonc.2021.773028openalex-snapshot
Metabolic Reprogramming of Thyroid Cancer Cells and Crosstalk in Their Microenvironment
inferred← citeshttps://doi.org/10.3389/fonc.2022.899987openalex-snapshot
The Deubiquitinase USP13 Maintains Cancer Cell Stemness by Promoting FASN Stability in Small Cell Lung Cancer
inferred← citeshttps://doi.org/10.3389/fonc.2024.1322090openalex-snapshot
Non-small cell lung cancer and metabolism research from 2013 to 2023: a visual analysis and bibliometric study
inferred← citeshttps://doi.org/10.3389/fphar.2021.671328openalex-snapshot
Restricting Glutamine Uptake Enhances NSCLC Sensitivity to Third-Generation EGFR-TKI Almonertinib
inferred← citeshttps://doi.org/10.3389/fphar.2021.730751openalex-snapshot
Role of Intra- and Extracellular Lipid Signals in Cancer Stemness and Potential Therapeutic Strategy
inferred← citeshttps://doi.org/10.3389/fphar.2024.1367981openalex-snapshot
Lipid metabolism dynamics in cancer stem cells: potential targets for cancers
inferred← citeshttps://doi.org/10.3389/fphar.2025.1674752openalex-snapshot
Fatty acid synthase in chemoresistance: mechanisms and therapeutic opportunities
inferred← citeshttps://doi.org/10.3390/biom16030473openalex-snapshot
Palmitoylation in Renal Physiology and Pathology
inferred← citeshttps://doi.org/10.3390/biomedicines10020277openalex-snapshot
Identification of Targetable Liabilities in the Dynamic Metabolic Profile of EGFR-Mutant Lung Adenocarcinoma: Thinking beyond Genomics for Overcoming EGFR TKI Resistance
inferred← citeshttps://doi.org/10.3390/biomedicines13030619openalex-snapshot
Functional Role of Fatty Acid Synthase for Signal Transduction in Core-Binding Factor Acute Myeloid Leukemia with an Activating c-Kit Mutation
inferred← citeshttps://doi.org/10.3390/cancers12051283openalex-snapshot
Fatty Acid Synthase Inhibitor G28 Shows Anticancer Activity in EGFR Tyrosine Kinase Inhibitor Resistant Lung Adenocarcinoma Models
inferred← citeshttps://doi.org/10.3390/cancers12061475openalex-snapshot
Non-Small-Cell Lung Cancer Signaling Pathways, Metabolism, and PD-1/PD-L1 Antibodies
inferred← citeshttps://doi.org/10.3390/cancers14153763openalex-snapshot
A Proof-of-Concept Inhibitor of Endothelial Lipase Suppresses Triple-Negative Breast Cancer Cells by Hijacking the Mitochondrial Function
inferred← citeshttps://doi.org/10.3390/cancers14194709openalex-snapshot
Fasudil Increased the Sensitivity to Gefitinib in NSCLC by Decreasing Intracellular Lipid Accumulation
inferred← citeshttps://doi.org/10.3390/cells11030413openalex-snapshot
Reprogramming of Lipid Metabolism in Lung Cancer: An Overview with Focus on EGFR-Mutated Non-Small Cell Lung Cancer
inferred← citeshttps://doi.org/10.3390/ijms242317060openalex-snapshot
Increased Lipogenesis Is Important for Hexavalent Chromium-Transformed Lung Cells and Xenograft Tumor Growth
inferred← citeshttps://doi.org/10.3390/ijms27177727openalex-snapshot
Longitudinal In Vivo Imaging at Single-Lesion Resolution Identifies Allele-Associated Response and Resistance Dynamics in EGFR-Mutant Lung Cancer
inferred← citeshttps://doi.org/10.3390/metabo12070644openalex-snapshot
Dysregulated Metabolism in EGFR-TKI Drug Resistant Non-Small-Cell Lung Cancer: A Systematic Review
inferred← citeshttps://doi.org/10.3390/metabo15030201openalex-snapshot
Nanomedicines Targeting Metabolic Pathways in the Tumor Microenvironment: Future Perspectives and the Role of AI
inferred← citeshttps://doi.org/10.3390/molecules25173935openalex-snapshot
Fatty Acid Synthase: An Emerging Target in Cancer
inferred← citeshttps://doi.org/10.3390/molecules25204831openalex-snapshot
Targeting Metabolism in Cancer Cells and the Tumour Microenvironment for Cancer Therapy
inferred← citeshttps://doi.org/10.3390/molecules28073211openalex-snapshot
Compound 275# Induces Mitochondria-Mediated Apoptosis and Autophagy Initiation in Colorectal Cancer Cells through an Accumulation of Intracellular ROS
inferred← citeshttps://doi.org/10.3390/ph18081238openalex-snapshot
VDR Decrease Enhances the Efficacy of 1,25-Dihydroxyvitamin D3 Inhibiting Gefitinib Resistance by Regulating EGFR/FASN Loop in NSCLC Cells
inferred← citeshttps://doi.org/10.34133/cancomm.0017openalex-snapshot
The Roles of Protein S -Palmitoylation in Cancers: From Dynamic Modulation to Therapeutic Potential
inferred← citeshttps://doi.org/10.3892/mco.2022.2513openalex-snapshot
Association between fatty acid synthase and adipophilin expression in triple‑negative breast cancer
inferred← citeshttps://doi.org/10.3892/ol.2020.11769openalex-snapshot
Implications of lipid droplets in lung cancer: Associations with drug resistance (Review)
inferred← citeshttps://doi.org/10.3892/ol.2022.13407openalex-snapshot
Tumor metabolic reprogramming in lung cancer progression (Review)
inferred← citeshttps://doi.org/10.3892/or.2019.7130openalex-snapshot
Heptadecanoic acid inhibits cell proliferation in PC‑9 non‑small‑cell lung cancer cells with acquired gefitinib resistance
inferred← citeshttps://doi.org/10.3892/or.2025.8950openalex-snapshot
Potential therapeutic target in oncology: Protein palmitoylation (Review)
inferred← citeshttps://doi.org/10.6084/m9.figshare.21087114openalex-snapshot
Additional file 2 of An IGF-1R-mTORC1-SRPK2 signaling Axis contributes to FASN regulation in breast cancer
inferred← citeshttps://doi.org/10.6084/m9.figshare.21087117openalex-snapshot
Additional file 3 of An IGF-1R-mTORC1-SRPK2 signaling Axis contributes to FASN regulation in breast cancer
inferred← citeshttps://doi.org/10.6084/m9.figshare.24546926openalex-snapshot
Additional file 1 of Missense variants in CYP4B1 associated with increased risk of lung cancer among Chinese Han population
inferred← citeshttps://doi.org/10.64898/2026.05.21.726063openalex-snapshot
Lipogenesis-driven EGFR palmitoylation enables metastatic immune evasion in triple-negative breast cancer
inferred← citeshttps://doi.org/10.7150/ijbs.45640openalex-snapshot
S-Palmitoylation as a Functional Regulator of Proteins Associated with Cisplatin Resistance in Bladder Cancer
inferred← citeshttps://doi.org/10.7150/ijbs.64046openalex-snapshot
Lipid-induced S-palmitoylation as a Vital Regulator of Cell Signaling and Disease Development
inferred← citeshttps://doi.org/10.7150/ijbs.66181openalex-snapshot
Close interactions between lncRNAs, lipid metabolism and ferroptosis in cancer
inferred← citeshttps://doi.org/10.7150/ijbs.72244openalex-snapshot
Emerging roles of protein palmitoylation and its modifying enzymes in cancer cell signal transduction and cancer therapy
inferred← citeshttps://doi.org/10.7150/ijbs.83468openalex-snapshot
Role of glycosphingolipid biosynthesis coregulators in malignant progression of thymoma
inferred← citeshttps://doi.org/10.7150/thno.35805openalex-snapshot
CAV1 - GLUT3 signaling is important for cellular energy and can be targeted by Atorvastatin in Non-Small Cell Lung Cancer
inferred← citeshttps://doi.org/10.7150/thno.38729openalex-snapshot
Targeting microtubule sensitizes drug resistant lung cancer cells to lysosomal pathway inhibitors
inferred← citeshttps://doi.org/10.7717/peerj.21160openalex-snapshot
Integrated analysis identifies a palmitoylation-associated prognostic model (ACSM5/SKA3) for lung adenocarcinoma across multiple cohorts
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