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Synthesis and Application of a pH-Responsive Functional Metal–Organic Framework: In Vitro Investigation for Delivery of Oridonin in Cancer Therapy

https://doi.org/10.3390/molecules29112643

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/aoc.6377openalex-snapshot

Experimental and molecular dynamics simulation study on the delivery of some common drugs by ZIF‐67, ZIF‐90, and ZIF‐8 zeolitic imidazolate frameworks

inferredcites →https://doi.org/10.1002/ddr.21055openalex-snapshot

Preparation, In Vitro, and In Vivo Antitumor Activity of Folate Receptor‐Targeted Nanoliposomes Containing Oridonin

inferredcites →https://doi.org/10.1002/slct.202204213openalex-snapshot

Corn‐like mSiO 2 @ZIF‐8 Composite Load with Curcumin for Target Cancer Drug‐Delivery System

inferredcites →https://doi.org/10.1002/smtd.202301270openalex-snapshot

Tunable Zeolitic Imidazolate Framework‐8 Nanoparticles for Biomedical Applications

inferredcites →https://doi.org/10.1007/s00604-020-4173-3openalex-snapshot

Zeolitic imidazolate frameworks for use in electrochemical and optical chemical sensing and biosensing: a review

inferredcites →https://doi.org/10.1007/s10563-014-9169-8openalex-snapshot

Zeolitic Imidazolate Frameworks: Synthesis, Functionalization, and Catalytic/Adsorption Applications

inferredcites →https://doi.org/10.1007/s10934-021-01184-zopenalex-snapshot

A review on zeolite imidazole frameworks: synthesis, properties, and applications

inferredcites →https://doi.org/10.1007/s11705-020-1927-8openalex-snapshot

Zeolitic imidazolate framework-8 (ZIF-8) for drug delivery: A critical review

inferredcites →https://doi.org/10.1016/j.apmt.2017.12.014openalex-snapshot

Biocompatibility characteristics of the metal organic framework ZIF-8 for therapeutical applications

inferredcites →https://doi.org/10.1016/j.apmt.2020.100821openalex-snapshot

Recent advances in metal organic frame photocatalysts for environment and energy applications

inferredcites →https://doi.org/10.1016/j.apsb.2016.09.006openalex-snapshot

Inhalable oridonin-loaded poly(lactic-co-glycolic)acid large porous microparticles for in situ treatment of primary non-small cell lung cancer

inferredcites →https://doi.org/10.1016/j.bcp.2020.114136openalex-snapshot

Oridonin is an antidepressant molecule working through the PPAR-γ/AMPA receptor signaling pathway

inferredcites →https://doi.org/10.1016/j.biochi.2016.07.008openalex-snapshot

Nano-formulations of drugs: Recent developments, impact and challenges

inferredcites →https://doi.org/10.1016/j.cej.2014.08.075openalex-snapshot

Thermal stability of ZIF-8 under oxidative and inert environments: A practical perspective on using ZIF-8 as a catalyst support

inferredcites →https://doi.org/10.1016/j.colsurfb.2019.110364openalex-snapshot

Natural drug physcion encapsulated zeolitic imidazolate framework, and their application as antimicrobial agent

inferredcites →https://doi.org/10.1016/j.colsurfb.2019.110481openalex-snapshot

Development and in vitro assessment of an anti-tumor nano-formulation

inferredcites →https://doi.org/10.1016/j.ejmech.2016.06.015openalex-snapshot

Discovery and development of natural product oridonin-inspired anticancer agents

inferredcites →https://doi.org/10.1016/j.hepres.2006.03.007openalex-snapshot

Oridonin inhibits cell growth by induction of apoptosis on human hepatocelluar carcinoma BEL-7402 cells

inferredcites →https://doi.org/10.1016/j.intimp.2019.04.006openalex-snapshot

Oridonin inhibits LPS-induced inflammation in human gingival fibroblasts by activating PPARγ

inferredcites →https://doi.org/10.1016/j.intimp.2023.110669openalex-snapshot

Oridonin enhances cytotoxic activity of natural killer cells against lung cancer

inferredcites →https://doi.org/10.1016/j.jsps.2017.04.037openalex-snapshot

Oridonin inhibits breast cancer growth and metastasis through blocking the Notch signaling

inferredcites →https://doi.org/10.1016/j.pdpdt.2022.102915openalex-snapshot

Enhanced permeability and retention effect: A key facilitator for solid tumor targeting by nanoparticles

inferredcites →https://doi.org/10.1016/j.phymed.2023.155179openalex-snapshot

The bioavailability enhancement and insight into the action mechanism of poorly soluble natural compounds from co-crystals preparation: Oridonin as an example

inferredcites →https://doi.org/10.1021/acs.accounts.5b00530openalex-snapshot

Metal–Organic Frameworks as Platforms for Functional Materials

inferredcites →https://doi.org/10.1021/acs.jafc.3c04299openalex-snapshot

A pH-Responsive Essential Oil Delivery System Based on Metal–organic Framework (ZIF-8) for Preventing Fungal Disease

inferredcites →https://doi.org/10.1021/acsnano.6b06658openalex-snapshot

Overcoming the Heat Endurance of Tumor Cells by Interfering with the Anaerobic Glycolysis Metabolism for Improved Photothermal Therapy

inferredcites →https://doi.org/10.1021/bm201270mopenalex-snapshot

Galactose-Decorated pH-Responsive Nanogels for Hepatoma-Targeted Delivery of Oridonin

inferredcites →https://doi.org/10.1039/c1cc15525copenalex-snapshot

In situ high pressure study of ZIF-8 by FTIR spectroscopy

inferredcites →https://doi.org/10.1039/c5ra24336jopenalex-snapshot

Surface defection reduces cytotoxicity of Zn(2-methylimidazole) 2 (ZIF-8) without compromising its drug delivery capacity

inferredcites →https://doi.org/10.1039/d0ra08560jopenalex-snapshot

Zeolitic imidazolate framework (ZIF)-derived porous carbon materials for supercapacitors: an overview

inferredcites →https://doi.org/10.1073/pnas.0602439103openalex-snapshot

Exceptional chemical and thermal stability of zeolitic imidazolate frameworks

inferredcites →https://doi.org/10.1080/03639040701834078openalex-snapshot

Characterization and In Vivo Evaluation of an Inclusion Complex of Oridonin and 2-hydroxypropyl-β-cyclodextrin

inferredcites →https://doi.org/10.1126/scitranslmed.3003562openalex-snapshot

Targeting of AML1-ETO in t(8;21) Leukemia by Oridonin Generates a Tumor Suppressor–Like Protein

inferredcites →https://doi.org/10.1155/2021/5023536openalex-snapshot

Oridonin Dose-Dependently Modulates the Cell Senescence and Apoptosis of Gastric Cancer Cells

inferredcites →https://doi.org/10.1158/1535-7163.mct-17-0823openalex-snapshot

Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo

inferredcites →https://doi.org/10.1186/s12906-017-1706-3openalex-snapshot

Antiangiogenic effects of oridonin

inferredcites →https://doi.org/10.1208/s12249-015-0363-4openalex-snapshot

Nanosuspensions Containing Oridonin/HP-β-Cyclodextrin Inclusion Complexes for Oral Bioavailability Enhancement via Improved Dissolution and Permeability

inferredcites →https://doi.org/10.2147/dddt.s387885openalex-snapshot

Antiviral Activity of Oridonin Against Herpes Simplex Virus Type 1

inferredcites →https://doi.org/10.2174/1389201024666230821110116openalex-snapshot

The Natural Product Oridonin as an Anticancer Agent: Current Achievements and Problems

inferredcites →https://doi.org/10.2174/1389450123666220822094248openalex-snapshot

Nanoformulations - Insights Towards Characterization Techniques

inferredcites →https://doi.org/10.2174/1567201817666200917120201openalex-snapshot

Progress of Stimuli-Responsive Nanoscale Metal Organic Frameworks as Controlled Drug Delivery Systems

inferredcites →https://doi.org/10.3389/fbioe.2021.600579openalex-snapshot

Oridonin-Loaded Nanoparticles Inhibit Breast Cancer Progression Through Regulation of ROS-Related Nrf2 Signaling Pathway

inferredcites →https://doi.org/10.3390/ijms17091395openalex-snapshot

Oridonin, a Promising ent-Kaurane Diterpenoid Lead Compound

inferredcites →https://doi.org/10.3390/molecules23020474openalex-snapshot

Therapeutic Potential of Oridonin and Its Analogs: From Anticancer and Antiinflammation to Neuroprotection

inferredcites →https://doi.org/10.3390/molecules25020332openalex-snapshot

Solubility and Bioavailability Enhancement of Oridonin: A Review

inferredcites →https://doi.org/10.3390/molecules25040960openalex-snapshot

Metal Organic Frameworks: Synthesis and Application

inferredcites →https://doi.org/10.3390/polym14214710openalex-snapshot

Progressive Trends on the Biomedical Applications of Metal Organic Frameworks

inferredcites →https://doi.org/10.6023/cjocx201607022openalex-snapshot

Preparation and Photocytotoxicity in vitro of Oridonin-porphyrinchitosan Microspheres

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1016/j.carres.2025.109611openalex-snapshot

Supramolecular vehicles based on cyclodextrin for dual-function delivery of podophyllotoxin: Effective treatment for tumors

inferred← citeshttps://doi.org/10.1016/j.cej.2025.168589openalex-snapshot

pH-responsive polymers: classification, response mode, properties and biomedical applications

inferred← citeshttps://doi.org/10.1016/j.microc.2026.118321openalex-snapshot

Hg(II)-activated colorimetric sensing platform using a Cu3(PO4)2@Cu2O/Cu-PA/ZIF-8 composite with low background and high signal amplification

inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.142425openalex-snapshot

Nano-encapsulation of epigallocatechin gallate (EGCG) within zeolitic imidazolate framework-8 (ZIF-8) and controlled release of EGCG

inferred← citeshttps://doi.org/10.1016/j.nxnano.2026.100787openalex-snapshot

Zeolitic Imidazolate Framework-8 (ZIF-8) as a versatile platform for targeted cancer drug delivery: A brief review

inferred← citeshttps://doi.org/10.1016/j.rechem.2025.102793openalex-snapshot

A dual drug delivery system based on pH-sensitive metal-organic frameworks: Synthesis, characterization, in vitro release and anticancer effect

inferred← citeshttps://doi.org/10.1021/acs.inorgchem.4c05281openalex-snapshot

Evaluation of the Potential of a Ratiometric Fluorescence Sensor for Sensitively Recognizing 1-Hydroxypyrene in Real Urine Samples Based on a Stable Zn-MOF

inferred← citeshttps://doi.org/10.1021/acsagscitech.6c00298openalex-snapshot

ZIF-8 Frameworks as Potential Controlled-Release Urea Fertilizers: Experimental and Computational Insights

inferred← citeshttps://doi.org/10.3389/fonc.2025.1606325openalex-snapshot

Research progress and molecular mechanism of oridonin in the treatment of malignant melanoma

inferred← citeshttps://doi.org/10.3389/fphar.2024.1476739openalex-snapshot

Enhancing cancer therapy: advanced nanovehicle delivery systems for oridonin

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