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G Protein–Coupled Receptor 56 Characterizes CTLs and Reflects the Progression of Lung Cancer Patients
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/jcp.27782openalex-snapshot
CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review
inferredcites →https://doi.org/10.1007/s11010-007-9621-4openalex-snapshot
Characterization of GPR56 protein and its suppressed expression in human pancreatic cancer cells
inferredcites →https://doi.org/10.1016/j.cell.2021.04.048openalex-snapshot
Integrated analysis of multimodal single-cell data
inferredcites →https://doi.org/10.1016/j.celrep.2016.04.053openalex-snapshot
The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells
inferredcites →https://doi.org/10.1016/j.celrep.2017.10.083openalex-snapshot
GPR56/ADGRG1 Inhibits Mesenchymal Differentiation and Radioresistance in Glioblastoma
inferredcites →https://doi.org/10.1016/j.chembiol.2005.03.006openalex-snapshot
Selective Chemical Functional Probes of Granzymes A and B Reveal Granzyme B Is a Major Effector of Natural Killer Cell-Mediated Lysis of Target Cells
inferredcites →https://doi.org/10.1016/j.chest.2016.10.010openalex-snapshot
The Eighth Edition Lung Cancer Stage Classification
inferredcites →https://doi.org/10.1016/j.neo.2017.05.002openalex-snapshot
UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses
inferredcites →https://doi.org/10.1038/leu.2015.26openalex-snapshot
Blocking programmed cell death 1 in combination with adoptive cytotoxic T-cell transfer eradicates chronic myelogenous leukemia stem cells
inferredcites →https://doi.org/10.1038/ni.3775openalex-snapshot
Tissue-resident memory features are linked to the magnitude of cytotoxic T cell responses in human lung cancer
inferredcites →https://doi.org/10.1038/nm.2253openalex-snapshot
CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung
inferredcites →https://doi.org/10.1038/s41467-017-01728-5openalex-snapshot
Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA
inferredcites →https://doi.org/10.1038/s41467-019-10018-1openalex-snapshot
Killer-like receptors and GPR56 progressive expression defines cytokine production of human CD4+ memory T cells
inferredcites →https://doi.org/10.1038/s41467-020-16164-1openalex-snapshot
Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma
inferredcites →https://doi.org/10.1038/sj.cdd.4401381openalex-snapshot
Granzyme B-mediated apoptosis – the elephant and the blind men?
inferredcites →https://doi.org/10.1038/sj.onc.1208395openalex-snapshot
GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion
inferredcites →https://doi.org/10.1038/srep10370openalex-snapshot
ImmuSort, a database on gene plasticity and electronic sorting for immune cells
inferredcites →https://doi.org/10.1084/jem.20091918openalex-snapshot
Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
inferredcites →https://doi.org/10.1084/jem.20091921openalex-snapshot
Naive tumor-specific CD4+ T cells differentiated in vivo eradicate established melanoma
inferredcites →https://doi.org/10.1111/j.0105-2896.2010.00908.xopenalex-snapshot
Cytotoxic and non‐cytotoxic roles of the CTL/NK protease granzyme B
inferredcites →https://doi.org/10.1111/j.1365-2893.2006.00723.xopenalex-snapshot
Cytotoxic CD4 + T cells in viral hepatitis
inferredcites →https://doi.org/10.1126/sciimmunol.aan8664openalex-snapshot
Precursors of human CD4 + cytotoxic T lymphocytes identified by single-cell transcriptome analysis
inferredcites →https://doi.org/10.1128/jvi.02493-10openalex-snapshot
Environmental and Antigen Receptor-Derived Signals Support Sustained Surveillance of the Lungs by Pathogen-Specific Cytotoxic T Lymphocytes
inferredcites →https://doi.org/10.1128/jvi.03474-14openalex-snapshot
Dynamics of the Cytotoxic T Cell Response to a Model of Acute Viral Infection
inferredcites →https://doi.org/10.1158/1538-7445.am2020-5148openalex-snapshot
Abstract 5148: ADGRG1 promotes tumorigenesis, invasion/migration, and cell-cell adhesion in triple-negative breast cancer cells
inferredcites →https://doi.org/10.1182/blood-2003-08-2765openalex-snapshot
Identification of circulating antigen-specific CD4+ T lymphocytes with a CCR5+, cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection
inferredcites →https://doi.org/10.1189/jlb.0211092openalex-snapshot
Specific expression of GPR56 by human cytotoxic lymphocytes
inferredcites →https://doi.org/10.1189/jlb.0909608openalex-snapshot
The battlefield of perforin/granzyme cell death pathways
inferredcites →https://doi.org/10.1371/journal.pone.0177405openalex-snapshot
Human CD8+ CD57- TEMRA cells: Too young to be called "old"
inferredcites →https://doi.org/10.2147/ott.s106907openalex-snapshot
Expression of G protein-coupled receptor 56 is associated with tumor progression in non-small-cell lung carcinoma patients
inferredcites →https://doi.org/10.3109/07357907.2010.512597openalex-snapshot
Clinical Significance of GPR56, Transglutaminase 2, and NF-κB in Esophageal Squamous Cell Carcinoma
inferredcites →https://doi.org/10.3389/fimmu.2017.00194openalex-snapshot
CD4 CTL, a Cytotoxic Subset of CD4+ T Cells, Their Differentiation and Function
inferredcites →https://doi.org/10.3389/fimmu.2023.1128423openalex-snapshot
A theoretical framework of immune cell phenotypic classification and discovery
inferredcites →https://doi.org/10.3389/fonc.2021.671895openalex-snapshot
ADGRG1 Is a Predictor of Chemoresistance and Poor Survival in Cervical Squamous Carcinoma
inferredcites →https://doi.org/10.4049/immunohorizons.2000059openalex-snapshot
T Cell–Intrinsic CX3CR1 Marks the Most Differentiated Effector CD4+ T Cells, but Is Largely Dispensable for CD4+ T Cell Responses during Chronic Viral Infection
inferredcites →https://doi.org/10.4049/jimmunol.1502552openalex-snapshot
Electronic Sorting of Immune Cell Subpopulations Based on Highly Plastic Genes
inferredcites →https://doi.org/10.4049/jimmunol.168.11.5954openalex-snapshot
Characterization of CD4+ CTLs Ex Vivo
inferredcites →https://doi.org/10.4049/jimmunol.168.12.6173openalex-snapshot
Dual Functions of Fractalkine/CX3C Ligand 1 in Trafficking of Perforin+/Granzyme B+ Cytotoxic Effector Lymphocytes That Are Defined by CX3CR1 Expression
inferredcites →https://doi.org/10.4049/jimmunol.1700946openalex-snapshot
Virtual Sorting Has a Distinctive Advantage in Identification of Anticorrelated Genes and Further Negative Regulators of Immune Cell Subpopulations
inferredcites →https://doi.org/10.4049/jimmunol.173.3.1834openalex-snapshot
Emergence of a CD4+CD28− Granzyme B+, Cytomegalovirus-Specific T Cell Subset after Recovery of Primary Cytomegalovirus Infection
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4687146openalex-extracted
Upregulated Circulating CD4 KLRD1 T Cells Exhibit Characteristics of CD4 Cytotoxic T Lymphocytes in Systemic Lupus Erythematosus Patients
inferred← citeshttps://doi.org/10.1002/advs.202514347openalex-snapshot
Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy
inferred← citeshttps://doi.org/10.1002/eji.70213openalex-snapshot
Identifying Negative Biomarkers of CD4 Cytotoxic T Lymphocytes via Granzyme B Exclusion Analysis
inferred← citeshttps://doi.org/10.1007/s10067-026-08418-yopenalex-snapshot
GPR56 and CD319 identify distinct cytotoxic-associated DP and DN T-cell subsets in early systemic lupus erythematosus
inferred← citeshttps://doi.org/10.1007/s12026-024-09522-4openalex-snapshot
Circulating CD8 + LGALS9 + T Cell Population Exhibiting Low Cytotoxic Characteristics are Decreased in Patients with Systemic Lupus Erythematosus
inferred← citeshttps://doi.org/10.1007/s12026-025-09703-9openalex-snapshot
Systematic correlation analysis of human CD molecules reveals upregulated co-expression of CD58, CD63, and CD147 in patients with primary Sjögren’s syndrome
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2026.120231openalex-snapshot
Microglial GPR56 in synaptic pruning: mechanisms, comparative receptor biology, and context-dependent roles in brain disorders
inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117728openalex-snapshot
CD4 CTLs in supercentenarians: Signs of adaptive expansion in healthy aging
inferred← citeshttps://doi.org/10.1016/j.diagmicrobio.2025.117222openalex-snapshot
Expression profiles of GPR56 and CD99 in T cells of AIDS patients and assessment of diagnostic value
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.111231openalex-snapshot
Upregulation of CX3CR1 expression in circulating T cells of systemic lupus erythematosus patients as a reflection of autoimmune status through characterization of cytotoxic capacity
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112072openalex-snapshot
KLRB1 defines an activated phenotype of CD4+ T cells and shows significant upregulation in patients with primary Sjögren's syndrome
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.114738openalex-snapshot
Novel diagnostic biomarker and immune profiling of GPR56+ B cell subsets in systemic lupus erythematosus
inferred← citeshttps://doi.org/10.1016/j.jaut.2024.103275openalex-snapshot
VNN2-expressing circulating monocytes exhibit unique functional characteristics and are decreased in patients with primary Sjögren's syndrome
inferred← citeshttps://doi.org/10.1016/j.jsbmb.2026.107093openalex-snapshot
GPR56 regulates the expression of key androgen-target genes via G13-Rho-PKN1 axis and is overexpressed in prostate cancer
inferred← citeshttps://doi.org/10.1016/j.pharmr.2026.100116openalex-snapshot
Adhesion G protein-coupled receptors
inferred← citeshttps://doi.org/10.1016/j.tig.2026.07.009openalex-snapshot
Uncovering an adaptive immune hallmark of extreme longevity
inferred← citeshttps://doi.org/10.1038/s41467-025-60329-9openalex-snapshot
SWI/SNF ATPase silenced HLF potentiates lung metastasis in solid cancers
inferred← citeshttps://doi.org/10.1038/s44319-026-00732-5openalex-snapshot
The AICL-KLRF1 axis supports CD4-CD8 T cell communication and cytokine competence in pre-exhausted CD8+ T cells
inferred← citeshttps://doi.org/10.1080/08820139.2024.2350549openalex-snapshot
Differential GPR56 Expression in T Cell Subpopulations for Early-Stage Lung Adenocarcinoma Patient Identification
inferred← citeshttps://doi.org/10.1093/jimmun/vkaf370openalex-snapshot
T cells co-expressing high levels of CD29 and CD99 show increased cytotoxic potential and are upregulated in Sjögren’s disease
inferred← citeshttps://doi.org/10.1093/jleuko/qiae145openalex-snapshot
Vanin-2 is expressed in peripheral blood T cells and upregulated in patients with systemic lupus erythematosus
inferred← citeshttps://doi.org/10.1111/febs.70089openalex-snapshot
Analysis of mutually exclusive expression in cancer cells identifies a previously unknown intergenic regulatory paradigm
inferred← citeshttps://doi.org/10.1111/imm.13819openalex-snapshot
Expression of GPR56 reflects a hypoactivated state of circulating B cells and is downregulated in B cell subsets in patients with early‐stage lung adenocarcinoma
inferred← citeshttps://doi.org/10.1111/imm.70073openalex-snapshot
GPR56 Outperforms CD319 as a Discriminative Marker for CD4 + Cytotoxic T Lymphocytes and Is Elevated in Primary Sjögren's Syndrome
inferred← citeshttps://doi.org/10.4049/jimmunol.2400228openalex-snapshot
The G Protein–Coupled Receptor GPR56 Is an Inhibitory Checkpoint for NK Cell Migration
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