On the public citation graph

Targeting the AKT pathway: Repositioning HIV protease inhibitors as radiosensitizers

https://doi.org/10.4103/0971-5916.180201
0 signed · 141 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.
Claim with ORCID
Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.
See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/14651858.cd002225openalex-snapshot
Concomitant chemotherapy and radiation therapy for cancer of the uterine cervix
inferredcites →https://doi.org/10.1002/14651858.cd002225.pub2openalex-snapshot
Concomitant chemotherapy and radiation therapy for cancer of the uterine cervix
inferredcites →https://doi.org/10.1002/hed.22954openalex-snapshot
Increased radioresistance via G12S K‐Ras by compensatory upregulation of MAPK and PI3K pathways in epithelial cancer
inferredcites →https://doi.org/10.1002/hed.23641openalex-snapshot
Accelerated radiotherapy for T1 to T2 glottic cancer
inferredcites →https://doi.org/10.1002/hed.23661openalex-snapshot
Concomitant chemoradiotherapy versus altered fractionation radiotherapy in the radiotherapeutic management of locoregionally advanced head and neck squamous cell carcinoma: An adjusted indirect comparison meta-analysis
inferredcites →https://doi.org/10.1002/ijc.2910640412openalex-snapshot
Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas
inferredcites →https://doi.org/10.1002/jcb.24465openalex-snapshot
mTOR inhibitors radiosensitize PTEN‐deficient non‐small‐cell lung cancer cells harboring an EGFR activating mutation by inducing autophagy
inferredcites →https://doi.org/10.1002/jcp.20666openalex-snapshot
Anti‐tumor activity of the combination of cetuximab, an anti‐EGFR blocking monoclonal antibody and ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinases
inferredcites →https://doi.org/10.1007/978-1-61779-397-4_2openalex-snapshot
The Role of Akt Pathway Signaling in Glucose Metabolism and Metabolic Oxidative Stress
inferredcites →https://doi.org/10.1007/s00066-014-0652-yopenalex-snapshot
Significance of p16 expression in head and neck cancer patients treated with radiotherapy and cetuximab
inferredcites →https://doi.org/10.1007/s10555-005-1577-9openalex-snapshot
Functional and therapeutic significance of Akt deregulation in malignant melanoma
inferredcites →https://doi.org/10.1016/j.biopha.2014.03.017openalex-snapshot
Inhibition of phosphoinositide 3-kinase is associated with reduced angiogenesis and an altered expression of angiogenic markers in endothelioma cells
inferredcites →https://doi.org/10.1016/j.canlet.2013.08.045openalex-snapshot
HIV protease inhibitor Lopinavir induces apoptosis of primary effusion lymphoma cells via suppression of NF-κB pathway
inferredcites →https://doi.org/10.1016/j.ctrv.2003.07.007openalex-snapshot
PI3K/Akt signalling pathway and cancer
inferredcites →https://doi.org/10.1016/j.ijrobp.2009.03.004openalex-snapshot
Radiation Response in Two HPV-Infected Head-and-Neck Cancer Cell Lines in Comparison to a Non–HPV-Infected Cell Line and Relationship to Signaling Through AKT
inferredcites →https://doi.org/10.1016/j.ijrobp.2011.05.057openalex-snapshot
K-RAS(V12) Induces Autocrine Production of EGFR Ligands and Mediates Radioresistance Through EGFR-Dependent Akt Signaling and Activation of DNA-PKcs
inferredcites →https://doi.org/10.1016/j.ijrobp.2011.06.171openalex-snapshot
Nelfinavir Induces Radiation Sensitization in Pituitary Adenoma Cells
inferredcites →https://doi.org/10.1016/j.ijrobp.2013.10.019openalex-snapshot
A Critical Role of the PTEN/PDGF Signaling Network for the Regulation of Radiosensitivity in Adenocarcinoma of the Prostate
inferredcites →https://doi.org/10.1016/j.lfs.2006.10.026openalex-snapshot
The involvement of phosphatidylinositol 3-kinase /Akt signaling in high glucose-induced downregulation of GLUT-1 expression in ARPE cells
inferredcites →https://doi.org/10.1016/j.lungcan.2012.02.022openalex-snapshot
Exploratory analysis of activation of PTEN–PI3K pathway and downstream proteins in malignant pleural mesothelioma (MPM)
inferredcites →https://doi.org/10.1016/j.molcel.2008.02.024openalex-snapshot
PKBα/Akt1 Acts Downstream of DNA-PK in the DNA Double-Strand Break Response and Promotes Survival
inferredcites →https://doi.org/10.1016/j.radonc.2009.04.014openalex-snapshot
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients
inferredcites →https://doi.org/10.1016/j.radonc.2011.03.004openalex-snapshot
Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck – A systematic review and meta-analysis
inferredcites →https://doi.org/10.1016/j.radonc.2011.05.036openalex-snapshot
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): A comprehensive analysis by tumour site
inferredcites →https://doi.org/10.1016/j.radonc.2011.06.002openalex-snapshot
Autophagy contributes to resistance of tumor cells to ionizing radiation
inferredcites →https://doi.org/10.1016/j.radonc.2011.06.022openalex-snapshot
Spatial relationship of phosphorylated epidermal growth factor receptor and activated AKT in head and neck squamous cell carcinoma
inferredcites →https://doi.org/10.1016/j.radonc.2011.09.010openalex-snapshot
Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck
inferredcites →https://doi.org/10.1016/j.radonc.2013.03.023openalex-snapshot
Phase I trial of the combination of the Akt inhibitor nelfinavir and chemoradiation for locally advanced rectal cancer
inferredcites →https://doi.org/10.1016/j.radonc.2013.06.023openalex-snapshot
Acquired resistance to cetuximab is associated with the overexpression of Ras family members and the loss of radiosensitization in head and neck cancer cells
inferredcites →https://doi.org/10.1016/j.radonc.2015.04.005openalex-snapshot
IAEA-HypoX. A randomized multicenter study of the hypoxic radiosensitizer nimorazole concomitant with accelerated radiotherapy in head and neck squamous cell carcinoma
inferredcites →https://doi.org/10.1016/s0014-5793(97)00240-8openalex-snapshot
Insulin activates protein kinase B, inhibits glycogen synthase kinase‐3 and activates glycogen synthase by rapamycin‐insensitive pathways in skeletal muscle and adipose tissue
inferredcites →https://doi.org/10.1016/s0022-5347(05)63998-5openalex-snapshot
Elevated Akt Activation and Its Impact on Clinicopathological Features of Renal Cell Carcinoma
inferredcites →https://doi.org/10.1016/s0140-6736(03)14361-9openalex-snapshot
Five compared with six fractions per week of conventional radiotherapy of squamous-cell carcinoma of head and neck: DAHANCA 6&7 randomised controlled trial
inferredcites →https://doi.org/10.1016/s0140-6736(05)67625-8openalex-snapshot
Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
inferredcites →https://doi.org/10.1016/s0167-8140(03)00011-2openalex-snapshot
Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers
inferredcites →https://doi.org/10.1016/s0360-3016(01)01446-8openalex-snapshot
Enhancement of radiosensitivity by proteasome inhibition: Implications for a role of NF-κB
inferredcites →https://doi.org/10.1016/s1040-1741(08)70163-5openalex-snapshot
Erlotinib in-Previously Treated Non-Small-Cell Lung Cancer
inferredcites →https://doi.org/10.1016/s1040-1741(08)70433-0openalex-snapshot
Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck
inferredcites →https://doi.org/10.1016/s1470-2045(08)70073-1openalex-snapshot
Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer
inferredcites →https://doi.org/10.1038/nrc1650openalex-snapshot
Repopulation of cancer cells during therapy: an important cause of treatment failure
inferredcites →https://doi.org/10.1038/nrc2714openalex-snapshot
Environment-mediated drug resistance: a major contributor to minimal residual disease
inferredcites →https://doi.org/10.1038/nrc704openalex-snapshot
Hypoxia — a key regulatory factor in tumour growth
inferredcites →https://doi.org/10.1038/nrc839openalex-snapshot
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
inferredcites →https://doi.org/10.1038/onc.2009.189openalex-snapshot
Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells
inferredcites →https://doi.org/10.1038/onc.2010.467openalex-snapshot
PKB/Akt promotes DSB repair in cancer cells through upregulating Mre11 expression following ionizing radiation
inferredcites →https://doi.org/10.1038/onc.2010.603openalex-snapshot
Targeting the Akt/mTOR pathway in Brca1-deficient cancers
inferredcites →https://doi.org/10.1038/onc.2012.211openalex-snapshot
Akt1 inhibits homologous recombination in Brca1-deficient cells by blocking the Chk1-Rad51 pathway
inferredcites →https://doi.org/10.1038/sj.bjc.6603180openalex-snapshot
Increased expression of pAKT is associated with radiation resistance in cervical cancer
inferredcites →https://doi.org/10.1038/sj.cdd.4402285openalex-snapshot
Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II
inferredcites →https://doi.org/10.1038/sj.cgt.7700673openalex-snapshot
Adenoviral-mediated PTEN transgene expression sensitizes Bcl-2-expressing prostate cancer cells to radiation
inferredcites →https://doi.org/10.1038/sj.leu.2402824openalex-snapshot
Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy
inferredcites →https://doi.org/10.1038/sj.leu.2402874openalex-snapshot
Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia: its significance as a prognostic variable
inferredcites →https://doi.org/10.1038/sj.onc.1201275openalex-snapshot
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation
inferredcites →https://doi.org/10.1038/sj.onc.1203598openalex-snapshot
Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer
inferredcites →https://doi.org/10.1038/sj.onc.1207525openalex-snapshot
Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs)
inferredcites →https://doi.org/10.1038/sj.onc.1207721openalex-snapshot
AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth
inferredcites →https://doi.org/10.1038/sj.onc.1208800openalex-snapshot
Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer
inferredcites →https://doi.org/10.1038/sj.onc.1210880openalex-snapshot
ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks
inferredcites →https://doi.org/10.1056/nejm197703032960905openalex-snapshot
Enzymology of Cancer Cells
inferredcites →https://doi.org/10.1056/nejm197703102961005openalex-snapshot
Enzymology of Cancer Cells
inferredcites →https://doi.org/10.1056/nejmoa050753openalex-snapshot
Erlotinib in Previously Treated Non–Small-Cell Lung Cancer
inferredcites →https://doi.org/10.1056/nejmoa053422openalex-snapshot
Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck
inferredcites →https://doi.org/10.1073/pnas.93.8.3636openalex-snapshot
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.
inferredcites →https://doi.org/10.1074/jbc.272.28.17269openalex-snapshot
Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades
inferredcites →https://doi.org/10.1074/jbc.c800210200openalex-snapshot
DNA-dependent Protein Kinase-mediated Phosphorylation of Protein Kinase B Requires a Specific Recognition Sequence in the C-terminal Hydrophobic Motif
inferredcites →https://doi.org/10.1074/jbc.m306782200openalex-snapshot
Isoform-specific Regulation of Insulin-dependent Glucose Uptake by Akt/Protein Kinase B
inferredcites →https://doi.org/10.1074/jbc.m611043200openalex-snapshot
Pivotal Role of the Cyclin-dependent Kinase Inhibitor p21WAF1/CIP1 in Apoptosis and Autophagy
inferredcites →https://doi.org/10.1093/carcin/23.1.201openalex-snapshot
AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis
inferredcites →https://doi.org/10.1093/carcin/bgh226openalex-snapshot
Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions
inferredcites →https://doi.org/10.1093/jnci/93.17.1337openalex-snapshot
Transcriptional Response to Hypoxia in Human Tumors
inferredcites →https://doi.org/10.1093/jrr/rrt054openalex-snapshot
Randomized phase III trial of concurrent chemoradiotherapy vs accelerated hyperfractionation radiotherapy in locally advanced head and neck cancer
inferredcites →https://doi.org/10.1097/01.ju.0000038952.59355.b2openalex-snapshot
Elevated Akt activation and its impact on clinicopathological features of renal cell carcinoma.
inferredcites →https://doi.org/10.1097/jto.0b013e3181a1084fopenalex-snapshot
Soluble mesothelin as a monitoring tool in the management of malignant mesothelioma patients
inferredcites →https://doi.org/10.1097/jto.0b013e3182435aa6openalex-snapshot
A Phase I Trial of the HIV Protease Inhibitor Nelfinavir with Concurrent Chemoradiotherapy for Unresectable Stage IIIA/IIIB Non-small Cell Lung Cancer: A Report of Toxicities and Clinical Response
inferredcites →https://doi.org/10.1097/maj.0b013e31811ec780openalex-snapshot
Liver Enzymes Elevation and Immune Reconstitution Among Treatment-Naïve HIV-Infected Patients Instituting Antiretroviral Therapy
inferredcites →https://doi.org/10.1097/ppo.0b013e318212dd3dopenalex-snapshot
Mechanism of Cell Adaptation
inferredcites →https://doi.org/10.1111/j.1349-7006.2005.00063.xopenalex-snapshot
HIV‐1 protease inhibitor induces growth arrest and apoptosis of human prostate cancer LNCaP cells in vitro and in vivo in conjunction with blockade of androgen receptor STAT3 and AKT signaling
inferredcites →https://doi.org/10.1111/j.1600-0463.2003.apm1111205.xopenalex-snapshot
Akt/PKB activation in gastric carcinomas correlates with clinicopathologic variables and prognosis
inferredcites →https://doi.org/10.1126/science.123.3191.309openalex-snapshot
On the Origin of Cancer Cells
inferredcites →https://doi.org/10.1136/jcp.2004.024786openalex-snapshot
Prognostic value of activated Akt expression in oral squamous cell carcinoma
inferredcites →https://doi.org/10.1158/0008-5472.can-03-1788openalex-snapshot
Serine/Threonine Kinase AKT Is Frequently Activated in Human Bile Duct Cancer and Is Associated with Increased Radioresistance
inferredcites →https://doi.org/10.1158/0008-5472.can-03-2904openalex-snapshot
Akt Stimulates Aerobic Glycolysis in Cancer Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-05-0513openalex-snapshot
Selective Inhibition of Ras, Phosphoinositide 3 Kinase, and Akt Isoforms Increases the Radiosensitivity of Human Carcinoma Cell Lines
inferredcites →https://doi.org/10.1158/0008-5472.can-05-1220openalex-snapshot
HIV Protease Inhibitors Block Akt Signaling and Radiosensitize Tumor Cells Both In vitro and In vivo
inferredcites →https://doi.org/10.1158/0008-5472.can-06-1239openalex-snapshot
Nelfinavir Down-regulates Hypoxia-Inducible Factor 1α and VEGF Expression and Increases Tumor Oxygenation: Implications for Radiotherapy
inferredcites →https://doi.org/10.1158/0008-5472.can-06-2722openalex-snapshot
Suppression of the Hypoxia-Inducible Factor-1 Response in Cervical Carcinoma Xenografts by Proteasome Inhibitors
inferredcites →https://doi.org/10.1158/0008-5472.can-06-3398openalex-snapshot
Phosphatase and Tensin Homologue Deficiency in Glioblastoma Confers Resistance to Radiation and Temozolomide that Is Reversed by the Protease Inhibitor Nelfinavir
inferredcites →https://doi.org/10.1158/0008-5472.can-06-3684openalex-snapshot
HIV Protease Inhibitors Enhance the Efficacy of Irradiation
inferredcites →https://doi.org/10.1158/0008-5472.can-07-0562openalex-snapshot
Blocked Autophagy Sensitizes Resistant Carcinoma Cells to Radiation Therapy
inferredcites →https://doi.org/10.1158/0008-5472.can-07-0796openalex-snapshot
HIV-1 Protease Inhibitors Nelfinavir and Atazanavir Induce Malignant Glioma Death by Triggering Endoplasmic Reticulum Stress
inferredcites →https://doi.org/10.1158/0008-5472.can-08-0861openalex-snapshot
AKT1 Inhibits Homologous Recombination by Inducing Cytoplasmic Retention of BRCA1 and RAD51
inferredcites →https://doi.org/10.1158/0008-5472.can-11-2263openalex-snapshot
Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature
inferredcites →https://doi.org/10.1158/1078-0432.ccr-05-2454openalex-snapshot
Blockage of Epidermal Growth Factor Receptor-Phosphatidylinositol 3-Kinase-AKT Signaling Increases Radiosensitivity of K-RAS Mutated Human Tumor Cells In vitro by Affecting DNA Repair
inferredcites →https://doi.org/10.1158/1535-7163.mct-12-0907openalex-snapshot
Tandutinib Inhibits the Akt/mTOR Signaling Pathway to Inhibit Colon Cancer Growth
inferredcites →https://doi.org/10.1158/1541-7786.mcr-06-0297openalex-snapshot
Stimulated PI3K-AKT Signaling Mediated through Ligand or Radiation-Induced EGFR Depends Indirectly, but not Directly, on Constitutive K-Ras Activity
inferredcites →https://doi.org/10.1158/1541-7786.mcr-11-0592openalex-snapshot
Akt Promotes Post-Irradiation Survival of Human Tumor Cells through Initiation, Progression, and Termination of DNA-PKcs–Dependent DNA Double-Strand Break Repair
inferredcites →https://doi.org/10.1172/jci40027openalex-snapshot
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
inferredcites →https://doi.org/10.1182/blood-2001-01-0317openalex-snapshot
Immunohistochemical localization of phosphorylated AKT in multiple myeloma
inferredcites →https://doi.org/10.1186/1748-717x-4-43openalex-snapshot
Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells
inferredcites →https://doi.org/10.1200/jco.2003.10.066openalex-snapshot
Phase II, Randomized Trial Comparing Bevacizumab Plus Fluorouracil (FU)/Leucovorin (LV) With FU/LV Alone in Patients With Metastatic Colorectal Cancer
inferredcites →https://doi.org/10.1200/jco.2004.07.193openalex-snapshot
The Prognostic Significance of Phosphatidylinositol 3-Kinase Pathway Activation in Human Gliomas
inferredcites →https://doi.org/10.1200/jco.2005.01.072openalex-snapshot
Tirapazamine, Cisplatin, and Radiation Versus Fluorouracil, Cisplatin, and Radiation in Patients With Locally Advanced Head and Neck Cancer: A Randomized Phase II Trial of the Trans-Tasman Radiation Oncology Group (TROG 98.02)
inferredcites →https://doi.org/10.1200/jco.2005.05.112openalex-snapshot
Addition of Bevacizumab to Bolus Fluorouracil and Leucovorin in First-Line Metastatic Colorectal Cancer: Results of a Randomized Phase II Trial
inferredcites →https://doi.org/10.1200/jco.2007.15.2355openalex-snapshot
Phase I Trial of the Human Immunodeficiency Virus Protease Inhibitor Nelfinavir and Chemoradiation for Locally Advanced Pancreatic Cancer
inferredcites →https://doi.org/10.1371/journal.pone.0095219openalex-snapshot
Activation of the PI3K/mTOR/AKT Pathway and Survival in Solid Tumors: Systematic Review and Meta-Analysis
inferredcites →https://doi.org/10.1507/endocrj.50.77openalex-snapshot
Increased Expression of Phosphorylated p70S6 Kinase and Akt in Papillary Thyroid Cancer Tissues
inferredcites →https://doi.org/10.1517/14656566.1.7.1429openalex-snapshot
Nelfinavir mesylate
inferredcites →https://doi.org/10.1517/14656566.2014.902445openalex-snapshot
Afatinib for the treatment of advanced non-small-cell lung cancer
inferredcites →https://doi.org/10.1593/neo.06535openalex-snapshot
HIV Protease Inhibitors Decrease VEGF/HIF-1α Expression and Angiogenesis in Glioblastoma Cells
inferredcites →https://doi.org/10.1593/neo.07124openalex-snapshot
The HIV Protease Inhibitor Nelfinavir Downregulates Akt Phosphorylation by Inhibiting Proteasomal Activity and Inducing the Unfolded Protein Response
inferredcites →https://doi.org/10.1667/0033-7587(2003)159[0283:sariao]2.0.co;2openalex-snapshot
Stress and Radiation-Induced Activation of Multiple Intracellular Signaling Pathways1
inferredcites →https://doi.org/10.1677/erc.0.0100203openalex-snapshot
Loss of PTEN expression followed by Akt phosphorylation is a poor prognostic factor for patients with endometrial cancer.
inferredcites →https://doi.org/10.1677/erc.1.00949openalex-snapshot
Enhanced protein kinase B/Akt signalling in pituitary tumours
inferredcites →https://doi.org/10.2174/156652406775574604openalex-snapshot
ER Stress, Hypoxia Tolerance and Tumor Progression
inferredcites →https://doi.org/10.3389/fnmol.2011.00051openalex-snapshot
PI3K/AKT/mTOR Pathway in Angiogenesis
inferredcites →https://doi.org/10.3802/kjgo.2006.17.1.33openalex-snapshot
Increased expression of pAKT is associated with radiation resistance in cervical cancer
inferredcites →https://doi.org/10.3892/or.11.1.25openalex-snapshot
Akt2 expression correlates with prognosis of human hepatocellular carcinoma
inferredcites →https://doi.org/10.3978/j.issn.2072-1439.2013.11.06openalex-snapshot
Hyperfractionated and accelerated radiotherapy in non-small cell lung cancer.
inferredcites →https://doi.org/10.4161/cbt.12.7.17172openalex-snapshot
Nelfinavir induces radiation sensitization in pituitary adenoma cells
inferredcites →https://doi.org/10.4161/cbt.27311openalex-snapshot
ERK2-dependent reactivation of Akt mediates the limited response of tumor cells with constitutive K-RAS activity to PI3K inhibition
inferredcites →https://doi.org/10.4161/cbt.7.5.5728openalex-snapshot
Validation and toxicity of PI3K/Akt pathway inhibition by HIV protease inhibitors in humans
inferredcites →https://doi.org/10.4161/cbt.7.5.6087openalex-snapshot
Progress towards the use of HIV proteases in cancer therapy
inferredcites →https://doi.org/10.4161/cc.10.13.16305openalex-snapshot
MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks
inferredcites →https://doi.org/10.4161/cc.2.4.433openalex-snapshot
Multiple Roles of the PI3K/PKB (Akt) Pathway in Cell Cycle Progression

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4706360openalex-extracted
Standard or High Dose Chemoradiotherapy, with or Without the Protease Inhibitor Nelfinavir, for the Treatment of Locally Advanced Pancreatic Cancer: Efficacy, Safety and Health-Related Quality of Life Outcomes from the Multi-Centre Two Stage Phase 1/Randomised Phase 2 SCALOP-2 Study
inferred← citeshttps://doi.org/10.1002/cncr.33449openalex-snapshot
Phase 1 trial of nelfinavir added to standard cisplatin chemotherapy with concurrent pelvic radiation for locally advanced cervical cancer
inferred← citeshttps://doi.org/10.1002/ijc.32730openalex-snapshot
HIV‐1, HAART and cancer: A complex relationship
inferred← citeshttps://doi.org/10.1016/j.ejca.2024.114236openalex-snapshot
Standard or high dose chemoradiotherapy, with or without the protease inhibitor nelfinavir, in patients with locally advanced pancreatic cancer: The phase 1/randomised phase 2 SCALOP-2 trial
inferred← citeshttps://doi.org/10.1016/j.semcancer.2019.09.010openalex-snapshot
What patents tell us about drug repurposing for cancer: A landscape analysis
inferred← citeshttps://doi.org/10.1016/s1470-2045(17)30440-0openalex-snapshot
Radiotherapy in patients with HIV: current issues and review of the literature
inferred← citeshttps://doi.org/10.1017/erm.2020.4openalex-snapshot
The radiobiology of HPV-positive and HPV-negative head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.2147/ott.s136484openalex-snapshot
The HIV protease inhibitor, nelfinavir, as a novel therapeutic approach for the treatment of refractory pediatric leukemia
inferred← citeshttps://doi.org/10.3390/cancers12113437openalex-snapshot
The Anti-Cancer Properties of the HIV Protease Inhibitor Nelfinavir
inferred← citeshttps://doi.org/10.3390/cells15121045openalex-snapshot
Repurposing Antiretroviral Drugs for Urological Cancers: Differential Effects of Protease Inhibitors and NNRTIs on Prostate and Bladder Cancer Cells
inferred← citeshttps://doi.org/10.3390/cells9051090openalex-snapshot
Modulation of mTORC1 Signaling Pathway by HIV-1
inferred← citeshttps://doi.org/10.3390/ijms19051270openalex-snapshot
The Novel Roles of Connexin Channels and Tunneling Nanotubes in Cancer Pathogenesis
inferred← citeshttps://doi.org/10.3390/ijms26146853openalex-snapshot
The Role of PI3K/AKT/mTOR Signaling in Tumor Radioresistance and Advances in Inhibitor Research
inferred← citeshttps://doi.org/10.3390/proteomes11030022openalex-snapshot
Oncogenic Proteomics Approaches for Translational Research and HIV-Associated Malignancy Mechanisms
inferred← citeshttps://doi.org/10.3892/ijo.2020.4966openalex-snapshot
New drugs are not enough‑drug repositioning in oncology: An update
inferred← citeshttps://doi.org/10.4103/jrcr.jrcr_41_17openalex-snapshot
Recent advances in radiation research for human health and environment
inferred← citeshttps://doi.org/10.70675/1d51b9d6z9a12z41f9z8f98z0c7f955aeb54openalex-snapshot
Factors that contribute to B cell oncogenesis in people living with HIV
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.