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Phase I Trial of the Human Immunodeficiency Virus Protease Inhibitor Nelfinavir and Chemoradiation for Locally Advanced Pancreatic Cancer

https://doi.org/10.1200/jco.2007.15.2355

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Acute toxicity of second generation HIV protease-inhibitors in combination with radiotherapy: a retrospective case series

inferred← citeshttps://doi.org/10.1186/1748-717x-9-146openalex-snapshot

Challenges in using 18 F-fluorodeoxyglucose-PET-CT to define a biological radiotherapy boost volume in locally advanced pancreatic cancer

inferred← citeshttps://doi.org/10.1186/bcr2602openalex-snapshot

Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells

inferred← citeshttps://doi.org/10.1186/s12885-019-5307-zopenalex-snapshot

Study protocol: a multi-centre randomised study of induction chemotherapy followed by capecitabine ± nelfinavir with high- or standard-dose radiotherapy for locally advanced pancreatic cancer (SCALOP-2)

inferred← citeshttps://doi.org/10.1186/s12885-019-6220-1openalex-snapshot

Lymphocyte-sparing effect of stereotactic body radiation therapy compared to conventional fractionated radiation therapy in patients with locally advanced pancreatic cancer

inferred← citeshttps://doi.org/10.1186/s12885-021-08514-zopenalex-snapshot

The association between protease inhibitors and anal cancer outcomes in veterans living with HIV treated with definitive chemoradiation: a retrospective study

inferred← citeshttps://doi.org/10.1186/s13014-017-0798-8openalex-snapshot

Quantification of renal function following stereotactic body radiotherapy for pancreatic cancer: secondary dosimetric analysis of a prospective clinical trial

inferred← citeshttps://doi.org/10.1186/s13046-018-0904-2openalex-snapshot

Effects of repurposed drug candidates nitroxoline and nelfinavir as single agents or in combination with erlotinib in pancreatic cancer cells

inferred← citeshttps://doi.org/10.1189/jlb.0911447openalex-snapshot

The HIV-1 protease inhibitor nelfinavir activates PP2 and inhibits MAPK signaling in macrophages: a pathway to reduce inflammation

inferred← citeshttps://doi.org/10.1200/jco.2014.59.7930openalex-snapshot

Approach to Patients With Pancreatic Cancer Without Detectable Metastases

inferred← citeshttps://doi.org/10.1200/jco.2016.67.9613openalex-snapshot

HIV Infection and Survival Among Women With Cervical Cancer

inferred← citeshttps://doi.org/10.1208/s12248-010-9181-5openalex-snapshot

Pancreatic Cancer: Pathobiology, Treatment Options, and Drug Delivery

inferred← citeshttps://doi.org/10.1210/jc.2013-3369openalex-snapshot

The HIV Protease Inhibitor Nelfinavir Down-Regulates RET Signaling and Induces Apoptosis in Medullary Thyroid Cancer Cells

inferred← citeshttps://doi.org/10.1245/s10434-015-5006-1openalex-snapshot

Outcomes of a Clinical Pathway for Borderline Resectable Pancreatic Cancer

inferred← citeshttps://doi.org/10.12688/f1000research.5827.1openalex-snapshot

Nelfinavir and other protease inhibitors in cancer: mechanisms involved in anticancer activity

inferred← citeshttps://doi.org/10.12688/f1000research.5827.2openalex-snapshot

Nelfinavir and other protease inhibitors in cancer: mechanisms involved in anticancer activity

inferred← citeshttps://doi.org/10.1371/journal.pone.0034240openalex-snapshot

Associations between HIV and Human Pathways Revealed by Protein-Protein Interactions and Correlated Gene Expression Profiles

inferred← citeshttps://doi.org/10.1517/14656566.2011.577066openalex-snapshot

Pharmacological management of Kaposi's sarcoma

inferred← citeshttps://doi.org/10.15252/embr.201642194openalex-snapshot

Pharmacological eEF2K activation promotes cell death and inhibits cancer progression

inferred← citeshttps://doi.org/10.1530/erc-16-0568openalex-snapshot

Nelfinavir inhibits proliferation and induces DNA damage in thyroid cancer cells

inferred← citeshttps://doi.org/10.1586/14737140.2014.919861openalex-snapshot

Optimal management of squamous cell carcinoma of the anal canal: where are we now?

inferred← citeshttps://doi.org/10.1586/era.12.18openalex-snapshot

The role of chemoradiation for patients with resectable or potentially resectable pancreatic cancer

inferred← citeshttps://doi.org/10.1586/eri.12.11openalex-snapshot

Immunomodulatory effects of antimicrobial agents. Part I: antibacterial and antiviral agents

inferred← citeshttps://doi.org/10.1684/bdc.2014.2035openalex-snapshot

Cancer de l’anus chez les patients séropositifs pour le VIH

inferred← citeshttps://doi.org/10.18632/oncotarget.2415openalex-snapshot

A phase I trial of the HIV protease inhibitor nelfinavir in adults with solid tumors

inferred← citeshttps://doi.org/10.2147/dddt.s102241openalex-snapshot

Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings

inferred← citeshttps://doi.org/10.2147/ott.s136484openalex-snapshot

The HIV protease inhibitor, nelfinavir, as a novel therapeutic approach for the treatment of refractory pediatric leukemia

inferred← citeshttps://doi.org/10.2147/ott.s72722openalex-snapshot

Advances in the targeted therapy of liposarcoma

inferred← citeshttps://doi.org/10.2147/tcrm.s82049openalex-snapshot

Marketed nonsteroidal anti-inflammatory agents, antihypertensives, and human immunodeficiency virus protease inhibitors: as-yet-unused weapons of the oncologists’ arsenal

inferred← citeshttps://doi.org/10.2174/0118715273329531240911075309openalex-snapshot

Revolutionising Neurological Therapeutics: Investigating Drug Repurposing Strategies

inferred← citeshttps://doi.org/10.3109/09553000903232827openalex-snapshot

Cell signalling and radiation survival: The impact of protein phosphatases

inferred← citeshttps://doi.org/10.3324/haematol.2015.135780openalex-snapshot

Treatment with the HIV protease inhibitor nelfinavir triggers the unfolded protein response and may overcome proteasome inhibitor resistance of multiple myeloma in combination with bortezomib: a phase I trial (SAKK 65/08)

inferred← citeshttps://doi.org/10.3389/fonc.2022.957373openalex-snapshot

Role of autophagy in tumor response to radiation: Implications for improving radiotherapy

inferred← citeshttps://doi.org/10.3390/cancers12113437openalex-snapshot

The Anti-Cancer Properties of the HIV Protease Inhibitor Nelfinavir

inferred← citeshttps://doi.org/10.3390/cancers13163946openalex-snapshot

Drug Repurposing, an Attractive Strategy in Pancreatic Cancer Treatment: Preclinical and Clinical Updates

inferred← citeshttps://doi.org/10.3390/cancers7030850openalex-snapshot

Molecular Targeted Intervention for Pancreatic Cancer

inferred← citeshttps://doi.org/10.3390/genes10010025openalex-snapshot

Targeting DNA Double-Strand Break Repair Pathways to Improve Radiotherapy Response

inferred← citeshttps://doi.org/10.3390/ph14030280openalex-snapshot

Drug Repurposing Opportunities in Pancreatic Ductal Adenocarcinoma

inferred← citeshttps://doi.org/10.3390/ph7010046openalex-snapshot

Ritonavir-Mediated Induction of Apoptosis in Pancreatic Cancer Occurs via the RB/E2F-1 and AKT Pathways

inferred← citeshttps://doi.org/10.3892/ol.2017.5835openalex-snapshot

Inhibition of MMP-9 expression by ritonavir or saquinavir is associated with inactivation of the AKT/Fra-1 pathway in cervical intraepithelial neoplasia cells

inferred← citeshttps://doi.org/10.3978/j.issn.2078-6891.2010.005openalex-snapshot

HIV- positive anal cancer: an update for the clinician.

inferred← citeshttps://doi.org/10.4103/0971-5916.180201openalex-snapshot

Targeting the AKT pathway: Repositioning HIV protease inhibitors as radiosensitizers

inferred← citeshttps://doi.org/10.4161/cbt.7.11.6846openalex-snapshot

Stromal SPARC expression and patient survival after chemoradiation for non-resectable pancreatic adenocarcinoma

inferred← citeshttps://doi.org/10.4161/cbt.8.3.7339openalex-snapshot

Nelfinavir induces the unfolded protein response in ovarian cancer cells, resulting in ER vacuolization, cell cycle retardation and apoptosis

inferred← citeshttps://doi.org/10.4161/cc.10.24.18616openalex-snapshot

Low-dose Hsp90 inhibitors tumor-selectively sensitize bladder cancer cells to chemoradiotherapy

inferred← citeshttps://doi.org/10.5772/19974openalex-snapshot

HIV and Lung Cancer

inferred← citeshttps://doi.org/10.6092/1590-8577/3332openalex-snapshot

Locally Advanced Pancreatic Adenocarcinoma: Where Are We and Where Are We Going?

inferred← citeshttps://doi.org/10.70675/1d51b9d6z9a12z41f9z8f98z0c7f955aeb54openalex-snapshot

Factors that contribute to B cell oncogenesis in people living with HIV

inferred← citeshttps://doi.org/10.70675/b41647f7zdd56z465cz9213zc11fff98c2caopenalex-snapshot

Effect of HIV antiretroviral drugs on antigen processing and epitope presentation by MHC-I to cytotoxic T cells

inferred← citeshttps://doi.org/10.7150/ijbs.9224openalex-snapshot

Recent Advances in Drug Repositioning for the Discovery of New Anticancer Drugs

inferred← citeshttps://doi.org/10.7243/2049-7962-1-32openalex-snapshot

Metronomic anti-cancer therapy – an ongoing treatment option for advanced cancer patients

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