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An atlas of the C. elegans starvation response reveals that transcription is necessary to initiate transcriptional silencing in quiescent primordial germ cells
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Restless legs syndrome‐associated MEIS1 risk variant influences iron homeostasis
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Schizosaccharomyces pombe atf1+ encodes a transcription factor required for sexual development and entry into stationary phase.
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The biology of the germ line in echinoderms
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Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
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Nutrient-Sensing Mechanisms across Evolution
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Enhancer Control of Transcriptional Bursting
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Molecular topography of an entire nervous system
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Pol II Docking and Pausing at Growth and Stress Genes in C. elegans
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A Long Noncoding RNA on the Ribosome Is Required for Lifespan Extension
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Genome-wide RNAi Screen for Fat Regulatory Genes in C. elegans Identifies a Proteostasis-AMPK Axis Critical for Starvation Survival
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Immunity-longevity tradeoff neurally controlled by GABAergic transcription factor PITX1/UNC-30
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DREAM represses distinct targets by cooperating with different THAP domain proteins
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Alternative somatic and germline gene-regulatory strategies during starvation-induced developmental arrest
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DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors
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Mitochondrial SKN-1/Nrf Mediates a Conserved Starvation Response
inferredcites →https://doi.org/10.1016/j.cmet.2016.05.024openalex-snapshot
Reversible Age-Related Phenotypes Induced during Larval Quiescence in C. elegans
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C. elegans DAF-18/PTEN Mediates Nutrient-Dependent Arrest of Cell Cycle and Growth in the Germline
inferredcites →https://doi.org/10.1016/j.cub.2006.03.021openalex-snapshot
DAF-16/FOXO Regulates Transcription of cki-1/Cip/Kip and Repression of lin-4 during C. elegans L1 Arrest
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The Tumor Suppressor Rb Critically Regulates Starvation-Induced Stress Response in C. elegans
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A Mummified Duck-Billed Dinosaur with a Soft-Tissue Cock’s Comb
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ROS Function in Redox Signaling and Oxidative Stress
inferredcites →https://doi.org/10.1016/j.devcel.2015.04.019openalex-snapshot
Zygotic Genome Activation Triggers Chromosome Damage and Checkpoint Signaling in C. elegans Primordial Germ Cells
inferredcites →https://doi.org/10.1016/j.devcel.2018.07.002openalex-snapshot
Programmed DNA Breaks Activate the Germline Genome in Caenorhabditis elegans
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HLH-30/TFEB Is a Master Regulator of Reproductive Quiescence
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Live-Cell Imaging of Chromatin Condensation Dynamics by CRISPR
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Condensin-Dependent Chromatin Compaction Represses Transcription Globally during Quiescence
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Transcription-mediated supercoiling regulates genome folding and loop formation
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Redox-mediated regulation of aging and healthspan by an evolutionarily conserved transcription factor HLH-2/Tcf3/E2A
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Liquid-culture protocols for synchronous starvation, growth, dauer formation, and dietary restriction of Caenorhabditis elegans
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Protocol for fast scRNA-seq raw data processing using scKB and non-arbitrary quality control with COPILOT
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Ins-4 and daf-28 function redundantly to regulate C. elegans L1 arrest
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The C. elegans PTEN Homolog, DAF-18, Acts in the Insulin Receptor-like Metabolic Signaling Pathway
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A C. elegans mutant that lives twice as long as wild type
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Repression of gene expression in the embryonic germ lineage of C. elegans
inferredcites →https://doi.org/10.1038/nature05837openalex-snapshot
PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans
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Two neurons mediate diet-restriction-induced longevity in C. elegans
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Dimensionality reduction for visualizing single-cell data using UMAP
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TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
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MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
inferredcites →https://doi.org/10.1038/ncomms3267openalex-snapshot
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NIH Image to ImageJ: 25 years of image analysis
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Molecular regulation of stem cell quiescence
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PHA-4/FoxA senses nucleolar stress to regulate lipid accumulation in Caenorhabditis elegans
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The DREAM complex functions as conserved master regulator of somatic DNA-repair capacities
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The molecular mechanisms of diapause and diapause-like reversible arrest
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Schizosaccharomyces pombe gad7 + encodes a phosphoprotein with a bZIP domain, which is required for proper G1 arrest and gene expression under nitrogen starvation
inferredcites →https://doi.org/10.1073/pnas.1002575107openalex-snapshot
Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity
inferredcites →https://doi.org/10.1073/pnas.1218778110openalex-snapshot
The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway
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Reevaluation of whether a soma–to–germ-line transformation extends lifespan in Caenorhabditis elegans
inferredcites →https://doi.org/10.1080/21624054.2015.1118607openalex-snapshot
GATA transcription factors as tissue-specific master regulators for induced responses
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A global chromatin compaction pathway that represses germline gene expression during starvation
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Transcriptome- and phenotype-based epistasis analysis in Caenorhabditis elegans reveals daf-16/FoxO -dependent and independent effects of daf-2/InsR in L1 starvation and recovery
inferredcites →https://doi.org/10.1093/genetics/163.1.171openalex-snapshot
Positive Selection of Caenorhabditis elegans Mutants With Increased Stress Resistance and Longevity
inferredcites →https://doi.org/10.1093/genetics/iyae049openalex-snapshot
Updates to the Alliance of Genome Resources central infrastructure
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WormBase 2024: status and transitioning to Alliance infrastructure
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Cel Est: a unified gene regulatory network for estimating transcription factor activities in C. elegans
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KEGG: biological systems database as a model of the real world
inferredcites →https://doi.org/10.1093/nar/gkag949openalex-snapshot
HLH-30/TFEB is necessary for chromatin reorganization and maintenance of cell quiescence during starvation in C. elegans
inferredcites →https://doi.org/10.1093/nar/gku1360openalex-snapshot
A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans
inferredcites →https://doi.org/10.1101/2024.08.28.609383openalex-snapshot
Autophagy-dependent proteome remodelling and ribosome decline balance starvation survival and recovery speed in C. elegans
inferredcites →https://doi.org/10.1101/gr.133587.111openalex-snapshot
Nutritional control of mRNA isoform expression during developmental arrest and recovery in C. elegans
inferredcites →https://doi.org/10.1111/acel.12509openalex-snapshot
Alzheimer‐related protein APL ‐1 modulates lifespan through heterochronic gene regulation in Caenorhabditis elegans
inferredcites →https://doi.org/10.1111/acel.12743openalex-snapshot
NHR ‐49/ HNF 4 integrates regulation of fatty acid metabolism with a protective transcriptional response to oxidative stress and fasting
inferredcites →https://doi.org/10.1111/acel.12982openalex-snapshot
Diet restriction‐induced healthy aging is mediated through the immune signaling component ZIP‐2 in Caenorhabditis elegans
inferredcites →https://doi.org/10.1111/j.1474-9726.2009.00482.xopenalex-snapshot
p53/CEP‐1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress
inferredcites →https://doi.org/10.1126/sciadv.adg0506openalex-snapshot
Whole-body gene expression atlas of an adult metazoan
inferredcites →https://doi.org/10.1126/science.1065486openalex-snapshot
Caenorhabditis elegans p53: Role in Apoptosis, Meiosis, and Stress Resistance
inferredcites →https://doi.org/10.1126/science.1169628openalex-snapshot
RNA Pol II Accumulates at Promoters of Growth Genes During Developmental Arrest
inferredcites →https://doi.org/10.1126/science.274.5285.209openalex-snapshot
An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex
inferredcites →https://doi.org/10.1126/science.aam8940openalex-snapshot
Comprehensive single-cell transcriptional profiling of a multicellular organism
inferredcites →https://doi.org/10.1126/science.aax1971openalex-snapshot
A lineage-resolved molecular atlas of C. elegans embryogenesis at single-cell resolution
inferredcites →https://doi.org/10.1128/ec.00446-07openalex-snapshot
Key Function for the CCAAT-Binding Factor Php4 To Regulate Gene Expression in Response to Iron Deficiency in Fission Yeast
inferredcites →https://doi.org/10.1128/ec.01.1.22-32.2002openalex-snapshot
Gcn4p, a Master Regulator of Gene Expression, Is Controlled at Multiple Levels by Diverse Signals of Starvation and Stress
inferredcites →https://doi.org/10.1128/mcb.20.2.429-440.2000openalex-snapshot
Helix-Loop-Helix Proteins: Regulators of Transcription in Eucaryotic Organisms
inferredcites →https://doi.org/10.1158/2159-8290.cd-15-0507openalex-snapshot
MYC, Metabolism, and Cancer
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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1242/bio.2012836openalex-snapshot
C. elegans AMPKs promote survival and arrest germline development during nutrient stress
inferredcites →https://doi.org/10.1242/dev.005611openalex-snapshot
Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice
inferredcites →https://doi.org/10.1242/dev.02232openalex-snapshot
Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling
inferredcites →https://doi.org/10.1242/dev.058131openalex-snapshot
Ci-Pem-1 localizes to the nucleus and represses somatic gene transcription in the germline of Ciona intestinalis embryos
inferredcites →https://doi.org/10.1242/dev.059501openalex-snapshot
synMuv B proteins antagonize germline fate in the intestine and ensure C. elegans survival
inferredcites →https://doi.org/10.1242/dev.166876openalex-snapshot
C. elegans PTEN and AMPK block neuroblast divisions by inhibiting a BMP-insulin-PP2A-MAPK pathway
inferredcites →https://doi.org/10.1261/rna.079073.121openalex-snapshot
FISH-quant v2: a scalable and modular tool for smFISH image analysis
inferredcites →https://doi.org/10.1371/journal.pbio.0030053openalex-snapshot
Nuclear Hormone Receptor NHR-49 Controls Fat Consumption and Fatty Acid Composition in C. elegans
inferredcites →https://doi.org/10.1371/journal.pgen.1000486openalex-snapshot
HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans
inferredcites →https://doi.org/10.1371/journal.pgen.1000848openalex-snapshot
Genome-Wide Identification of Binding Sites Defines Distinct Functions for Caenorhabditis elegans PHA-4/FOXA in Development and Environmental Response
inferredcites →https://doi.org/10.1371/journal.pgen.1002542openalex-snapshot
Repression of Germline RNAi Pathways in Somatic Cells by Retinoblastoma Pathway Chromatin Complexes
inferredcites →https://doi.org/10.1371/journal.pgen.1003739openalex-snapshot
Conserved Translatome Remodeling in Nematode Species Executing a Shared Developmental Transition
inferredcites →https://doi.org/10.1371/journal.pgen.1005265openalex-snapshot
The Developmental Intestinal Regulator ELT-2 Controls p38-Dependent Immune Responses in Adult C. elegans
inferredcites →https://doi.org/10.1371/journal.pgen.1005731openalex-snapshot
dbl-1/TGF-β and daf-12/NHR Signaling Mediate Cell-Nonautonomous Effects of daf-16/FOXO on Starvation-Induced Developmental Arrest
inferredcites →https://doi.org/10.1371/journal.pgen.1006738openalex-snapshot
DAF-18/PTEN signals through AAK-1/AMPK to inhibit MPK-1/MAPK in feedback control of germline stem cell proliferation
inferredcites →https://doi.org/10.1371/journal.pgen.1009573openalex-snapshot
Phosphatidylcholine mediates the crosstalk between LET-607 and DAF-16 stress response pathways
inferredcites →https://doi.org/10.1371/journal.pgen.1009650openalex-snapshot
DAF-18/PTEN inhibits germline zygotic gene activation during primordial germ cell quiescence
inferredcites →https://doi.org/10.1371/journal.pone.0048282openalex-snapshot
Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks
inferredcites →https://doi.org/10.1534/genetics.113.150847openalex-snapshot
To Grow or Not to Grow: Nutritional Control of Development DuringCaenorhabditis elegansL1 Arrest
inferredcites →https://doi.org/10.1534/genetics.115.178699openalex-snapshot
Transgenerational Effects of Early Life Starvation on Growth, Reproduction, and Stress Resistance inCaenorhabditis elegans
inferredcites →https://doi.org/10.1534/genetics.118.301250openalex-snapshot
Transgenerational Effects of Extended Dauer Diapause on Starvation Survival and Gene Expression Plasticity in Caenorhabditis elegans
inferredcites →https://doi.org/10.1534/genetics.120.303565openalex-snapshot
Starvation Responses Throughout theCaenorhabditis elegansLife Cycle
inferredcites →https://doi.org/10.18632/aging.100604openalex-snapshot
TAF-4 is required for the life extension of isp-1, clk-1 and tpk-1 Mit mutants
inferredcites →https://doi.org/10.21769/bioprotoc.2357openalex-snapshot
Single-molecule RNA Fluorescence in situ Hybridization (smFISH) in Caenorhabditis elegans
inferredcites →https://doi.org/10.26508/lsa.202403147openalex-snapshot
DAF-18/PTEN protects LIN-35/Rb from CLP-1/CAPN-mediated cleavage to promote starvation resistance
inferredcites →https://doi.org/10.3389/fnmol.2023.1112253openalex-snapshot
A stay of execution: ATF4 regulation and potential outcomes for the integrated stress response
inferredcites →https://doi.org/10.7554/elife.30057openalex-snapshot
daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival
inferredcites →https://doi.org/10.7554/elife.44425openalex-snapshot
Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity
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