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Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/cyto.990050108openalex-snapshot
Filipin as a flow microfluorometry probe for cellular cholesterol
inferredcites →https://doi.org/10.1006/meth.2001.1262openalex-snapshot
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
inferredcites →https://doi.org/10.1016/j.bbalip.2011.07.011openalex-snapshot
Dancing with the sterols: Critical roles for ABCG1, ABCA1, miRNAs, and nuclear and cell surface receptors in controlling cellular sterol homeostasis
inferredcites →https://doi.org/10.1016/j.cell.2008.04.052openalex-snapshot
LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response
inferredcites →https://doi.org/10.1016/j.cell.2009.06.049openalex-snapshot
Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes
inferredcites →https://doi.org/10.1016/j.cell.2016.09.031openalex-snapshot
L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity
inferredcites →https://doi.org/10.1016/j.cell.2018.10.001openalex-snapshot
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
inferredcites →https://doi.org/10.1016/j.celrep.2012.02.007openalex-snapshot
PI3K-Akt-mTORC1-S6K1/2 Axis Controls Th17 Differentiation by Regulating Gfi1 Expression and Nuclear Translocation of RORγ
inferredcites →https://doi.org/10.1016/j.cmet.2016.06.007openalex-snapshot
Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation
inferredcites →https://doi.org/10.1016/j.cmet.2016.12.011openalex-snapshot
Serine Is an Essential Metabolite for Effector T Cell Expansion
inferredcites →https://doi.org/10.1016/j.cmet.2018.08.009openalex-snapshot
The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling
inferredcites →https://doi.org/10.1016/j.immuni.2011.09.021openalex-snapshot
The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
inferredcites →https://doi.org/10.1016/j.immuni.2013.09.015openalex-snapshot
T Cell Exit from Quiescence and Differentiation into Th2 Cells Depend on Raptor-mTORC1-Mediated Metabolic Reprogramming
inferredcites →https://doi.org/10.1016/j.immuni.2017.02.010openalex-snapshot
Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation
inferredcites →https://doi.org/10.1016/j.it.2016.09.001openalex-snapshot
The Intracellular Cholesterol Landscape: Dynamic Integrator of the Immune Response
inferredcites →https://doi.org/10.1016/j.molcel.2009.05.006openalex-snapshot
GPS2 Is Required for Cholesterol Efflux by Triggering Histone Demethylation, LXR Recruitment, and Coregulator Assembly at the ABCG1 Locus
inferredcites →https://doi.org/10.1016/j.tibs.2003.10.002openalex-snapshot
The intracellular voyage of cholera toxin: going retro
inferredcites →https://doi.org/10.1016/j.tibs.2018.01.005openalex-snapshot
SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond
inferredcites →https://doi.org/10.1016/s1074-7613(00)80375-1openalex-snapshot
An Enhancer That Directs Lineage-Specific Expression of CD8 in Positively Selected Thymocytes and Mature T Cells
inferredcites →https://doi.org/10.1038/cdd.2017.52openalex-snapshot
A defined metabolic state in pre B cells governs B-cell development and is counterbalanced by Swiprosin-2/EFhd1
inferredcites →https://doi.org/10.1038/emboj.2008.51openalex-snapshot
Liver‐specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks
inferredcites →https://doi.org/10.1038/nature12297openalex-snapshot
mTORC1 couples immune signals and metabolic programming to establish Treg-cell function
inferredcites →https://doi.org/10.1038/nature17412openalex-snapshot
Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism
inferredcites →https://doi.org/10.1038/ni.2570openalex-snapshot
Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity
inferredcites →https://doi.org/10.1038/nri3156openalex-snapshot
The role of interleukin-2 during homeostasis and activation of the immune system
inferredcites →https://doi.org/10.1038/s41467-019-09152-7openalex-snapshot
Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism
inferredcites →https://doi.org/10.1038/s41568-018-0074-8openalex-snapshot
mTOR signalling and cellular metabolism are mutual determinants in cancer
inferredcites →https://doi.org/10.1038/s41577-019-0203-yopenalex-snapshot
Metabolic coordination of T cell quiescence and activation
inferredcites →https://doi.org/10.1084/jem.20092136openalex-snapshot
Antigen-specific clonal expansion and cytolytic effector function of CD8+ T lymphocytes depend on the transcription factor Bcl11b
inferredcites →https://doi.org/10.1084/jem.20191453openalex-snapshot
Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells
inferredcites →https://doi.org/10.1084/jem.20201311openalex-snapshot
Nuclear receptor LXRβ controls fitness and functionality of activated T cells
inferredcites →https://doi.org/10.1128/mcb.00706-15openalex-snapshot
Histone Deacetylase 3 Is Required for Efficient T Cell Development
inferredcites →https://doi.org/10.1146/annurev-immunol-042617-053352openalex-snapshot
Signaling and Function of Interleukin-2 in T Lymphocytes
inferredcites →https://doi.org/10.1158/2326-6066.cir-17-0605openalex-snapshot
Hallmarks of T-cell Exit from Quiescence
inferredcites →https://doi.org/10.1371/journal.pone.0016053openalex-snapshot
Optimizing Optical Flow Cytometry for Cell Volume-Based Sorting and Analysis
inferredcites →https://doi.org/10.3389/fimmu.2017.01664openalex-snapshot
Cholesterol Metabolism in T Cells
inferredcites →https://doi.org/10.4049/jimmunol.0902372openalex-snapshot
ATP-Binding Cassette Transporter G1 Negatively Regulates Thymocyte and Peripheral Lymphocyte Proliferation
inferredcites →https://doi.org/10.4049/jimmunol.1100253openalex-snapshot
Intracellular Lipid Flux and Membrane Microdomains as Organizing Principles in Inflammatory Cell Signaling
inferredcites →https://doi.org/10.4049/jimmunol.1500435openalex-snapshot
Histone Deacetylase 3 Is Required for T Cell Maturation
inferredcites →https://doi.org/10.4049/jimmunol.1502529openalex-snapshot
HDAC3 Is Required for the Downregulation of RORγt during Thymocyte Positive Selection
inferredcites →https://doi.org/10.4049/jimmunol.163.12.6355openalex-snapshot
Cutting Edge: Absence of Expression of RAG1 in Peritoneal B-1 Cells Detected by Knocking into RAG1 Locus with Green Fluorescent Protein Gene
inferredcites →https://doi.org/10.4049/jimmunol.174.11.6725openalex-snapshot
Selective Expression of the Cre Recombinase in Late-Stage Thymocytes Using the Distal Promoter of the Lck Gene
inferredcites →https://doi.org/10.4049/jimmunol.1801438openalex-snapshot
Cutting Edge: HDAC3 Protects Double-Positive Thymocytes from P2X7 Receptor–Induced Cell Death
inferredcites →https://doi.org/10.7554/elife.43821openalex-snapshot
HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4+CD8+ thymocytes for CD4-lineage commitment
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4760648openalex-extracted
Cholesterol Metabolism-Mediated Immune Regulation and Cancer Immunotherapy
inferred← citeshttps://doi.org/10.1002/acr2.90131openalex-snapshot
Large‐Scale Autoantibody Reactome Analysis Reveals Shared and Specific Signatures Across Different Immune‐Mediated Inflammatory Diseases
inferred← citeshttps://doi.org/10.1007/s10238-022-00939-5openalex-snapshot
CYP51-mediated cholesterol biosynthesis is required for the proliferation of CD4+ T cells in Sjogren’s syndrome
inferred← citeshttps://doi.org/10.1007/s11883-023-01125-yopenalex-snapshot
T-cell Cholesterol Accumulation, Aging, and Atherosclerosis
inferred← citeshttps://doi.org/10.1016/j.carbpol.2026.125777openalex-snapshot
An alginate-based biomimetic nanozyme metabolic immunomodulator for sensitizing photothermal-immunotherapy in postoperative breast cancer
inferred← citeshttps://doi.org/10.1016/j.cmet.2025.09.008openalex-snapshot
Nutrient allocation fuels T cell-mediated immunity
inferred← citeshttps://doi.org/10.1016/j.imlet.2026.107143openalex-snapshot
Molecular requirements of pathogenic Th2 cell differentiation in allergic airway disease
inferred← citeshttps://doi.org/10.1016/j.jaci.2022.09.025openalex-snapshot
Sterols and immune mechanisms in asthma
inferred← citeshttps://doi.org/10.1038/s41392-026-02764-8openalex-snapshot
The histone deacetylase family in health and disease
inferred← citeshttps://doi.org/10.1038/s41467-022-31135-4openalex-snapshot
T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice
inferred← citeshttps://doi.org/10.1038/s41590-023-01733-5openalex-snapshot
Metabolic waypoints during T cell differentiation
inferred← citeshttps://doi.org/10.1096/fj.202300515ropenalex-snapshot
Cholesterol metabolism in T‐cell aging: Accomplices or victims
inferred← citeshttps://doi.org/10.1111/imm.13913openalex-snapshot
Targeting Immune Cell Metabolism: A Promising Therapeutic Approach for Cardiovascular Disease
inferred← citeshttps://doi.org/10.1111/imr.13200openalex-snapshot
Decoding the crosstalk between mevalonate metabolism and T cell function
inferred← citeshttps://doi.org/10.3389/fphar.2023.1191692openalex-snapshot
HECT, UBA and WWE domain containing 1 represses cholesterol efflux during CD4+ T cell activation in Sjögren’s syndrome
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