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Metabolite profiling of CHO cells with different growth characteristics

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bit.23269openalex-snapshot
Metabolite profiling of recombinant CHO cells: Designing tailored feeding regimes that enhance recombinant antibody production
inferredcites →https://doi.org/10.1002/btpr.238openalex-snapshot
A single nutrient feed supports both chemically defined NS0 and CHO fed‐batch processes: Improved productivity and lactate metabolism
inferredcites →https://doi.org/10.1002/btpr.470openalex-snapshot
Towards the implementation of quality by design to the production of therapeutic monoclonal antibodies with desired glycosylation patterns
inferredcites →https://doi.org/10.1002/rcm.4328openalex-snapshot
Metabolomics profiling of extracellular metabolites in recombinant Chinese Hamster Ovary fed‐batch culture
inferredcites →https://doi.org/10.1007/bf00928361openalex-snapshot
Physiological concentrations of purines and pyrimidines
inferredcites →https://doi.org/10.1007/s11306-010-0216-9openalex-snapshot
Evaluation of extraction processes for intracellular metabolite profiling of mammalian cells: matching extraction approaches to cell type and metabolite targets
inferredcites →https://doi.org/10.1016/j.ab.2010.04.031openalex-snapshot
Towards quantitative metabolomics of mammalian cells: Development of a metabolite extraction protocol
inferredcites →https://doi.org/10.1016/j.drudis.2010.06.012openalex-snapshot
Cell culture metabolomics: applications and future directions
inferredcites →https://doi.org/10.1016/j.jbiotec.2010.03.018openalex-snapshot
Metabolomics-driven approach for the improvement of Chinese hamster ovary cell growth: Overexpression of malate dehydrogenase II
inferredcites →https://doi.org/10.1016/j.ymben.2009.11.001openalex-snapshot
Metabolomics for high-resolution monitoring of the cellular physiological state in cell culture engineering
inferredcites →https://doi.org/10.1016/s0021-9258(18)95956-9openalex-snapshot
Adenosine Triphosphate Conservation in Metabolic Regulation
inferredcites →https://doi.org/10.1021/ac2009492openalex-snapshot
Metabolomics Profiling of Cell Culture Media Leading to the Identification of Riboflavin Photosensitized Degradation of Tryptophan Causing Slow Growth in Cell Culture
inferredcites →https://doi.org/10.1021/ja101962copenalex-snapshot
Fermentanomics: Monitoring Mammalian Cell Cultures with NMR Spectroscopy
inferredcites →https://doi.org/10.1021/pr8006232openalex-snapshot
Metabolic Profiling of Human Colorectal Cancer Using High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance (HR-MAS NMR) Spectroscopy and Gas Chromatography Mass Spectrometry (GC/MS)
inferredcites →https://doi.org/10.1038/nmeth0211-117openalex-snapshot
Metabolomics: from small molecules to big ideas
inferredcites →https://doi.org/10.1073/pnas.0502267102openalex-snapshot
Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements
inferredcites →https://doi.org/10.1089/omi.2010.0114openalex-snapshot
Metabolomic Analysis of Resveratrol-Induced Effects in the Human Breast Cancer Cell Lines MCF-7 and MDA-MB-231
inferredcites →https://doi.org/10.1093/nar/27.1.29openalex-snapshot
KEGG: Kyoto Encyclopedia of Genes and Genomes
inferredcites →https://doi.org/10.1093/nar/28.1.27openalex-snapshot
KEGG: Kyoto Encyclopedia of Genes and Genomes
inferredcites →https://doi.org/10.1126/science.122.3168.501openalex-snapshot
Nutrition Needs of Mammalian Cells in Tissue Culture
inferredcites →https://doi.org/10.1134/s0006297909090156openalex-snapshot
Essentials of glycobiology
inferredcites →https://doi.org/10.1142/9789812772435_0018openalex-snapshot
COMPARATIVE METABOLOMICS OF BREAST CANCER
inferredcites →https://doi.org/10.1186/1471-2105-9-11openalex-snapshot
SeqAn An efficient, generic C++ library for sequence analysis
inferredcites →https://doi.org/10.1186/1471-2105-9-199openalex-snapshot
anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data
inferredcites →https://doi.org/10.1371/journal.pone.0004251openalex-snapshot
Metabolomic Profiling of Drug Responses in Acute Myeloid Leukaemia Cell Lines

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Optimization of Metabolomics Pretreatment Method of Cholangiocarcinoma Cells Based on Ultrahigh Performance Liquid Chromatography Coupled with Mass Spectrometry
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Optimization of Metabolomics Pretreatment Method of Cholangiocarcinoma Cells Based on Ultrahigh Performance Liquid Chromatography Coupled with Mass Spectrometry
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Metabolite Profiling of Mammalian Cells
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Toward Integrated Multi‐omics Analysis for Improving CHO Cell Bioprocessing
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Single‐Use, Metabolite Absorbing, Resonant Transducer (SMART) Culture Vessels for Label‐Free, Continuous Cell Culture Progression Monitoring
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Productive CHO cell lines selection in biopharm process development through machine learning on metabolomic dynamics
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High‐throughput nucleoside phosphate monitoring in mammalian cell fed‐batch cultivation using quantitative matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry
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A robust transfection reagent for the transfection of CHO and HEK293 cells and production of recombinant proteins and lentiviral particles – PTG1
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Metabolite profiling of CHO cells: Molecular reflections of bioprocessing effectiveness
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Impact of CHO Metabolism on Cell Growth and Protein Production: An Overview of Toxic and Inhibiting Metabolites and Nutrients
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High Cell Density Perfusion Culture has a Maintained Exoproteome and Metabolome
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1H NMR‐based process understanding and biochemical marker identification methodology for monitoring CHO cell culture process during commercial‐scale manufacturing
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Metabolic Footprint of Drosophila S2 Cells: Findings During the Production of a Recombinant Rabies Virus Glycoprotein
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An 'omics approach towards CHO cell engineering
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Enhanced FK506 production in Streptomyces tsukubaensis by rational feeding strategies based on comparative metabolic profiling analysis
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Metabolic signatures of GS‐CHO cell clones associated with butyrate treatment and culture phase transition
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Metabolic profiling of insect cell lines: Unveiling cell line determinants behind system's productivity
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Characterization of intrinsic variability in time‐series metabolomic data of cultured mammalian cells
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The use of ‘Omics technology to rationally improve industrial mammalian cell line performance
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A hybrid approach identifies metabolic signatures of high‐producers for chinese hamster ovary clone selection and process optimization
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Identification and control of novel growth inhibitors in fed‐batch cultures of Chinese hamster ovary cells
inferred← citeshttps://doi.org/10.1002/bit.27661openalex-snapshot
Creation and filtering of a recurrent spectral library of CHO cell metabolites and media components
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Using MVDA with stoichiometric balances to optimize amino acid concentrations in chemically defined CHO cell culture medium for improved culture performance
inferred← citeshttps://doi.org/10.1002/btpr.2335openalex-snapshot
Effect of amino acid supplementation on titer and glycosylation distribution in hybridoma cell cultures—Systems biology‐based interpretation using genome‐scale metabolic flux balance model and multivariate data analysis
inferred← citeshttps://doi.org/10.1002/btpr.2421openalex-snapshot
Intracellular CHO Cell Metabolite Profiling Reveals Steady‐State Dependent Metabolic Fingerprints in Perfusion Culture
inferred← citeshttps://doi.org/10.1002/btpr.3220openalex-snapshot
Metabolic trends of Chinese hamster ovary cells in biopharmaceutical production under batch and fed‐batch conditions
inferred← citeshttps://doi.org/10.1002/elps.201200605openalex-snapshot
Mammalian cell metabolomics: Experimental design and sample preparation
inferred← citeshttps://doi.org/10.1007/164_2022_619openalex-snapshot
Metabolomics in Cell Biology
inferred← citeshttps://doi.org/10.1007/978-1-0716-4104-0_9openalex-snapshot
The ‘Omics Revolution in CHO Biology: Roadmap to Improved CHO Productivity
inferred← citeshttps://doi.org/10.1007/978-1-4939-6972-2_10openalex-snapshot
The ‘Omics Revolution in CHO Biology: Roadmap to Improved CHO Productivity
inferred← citeshttps://doi.org/10.1007/978-3-030-79871-0_4openalex-snapshot
An Omic’s Data-Driven Approach Towards Engineering Mammalian Cell Factories and Bioprocesses for Biopharmaceutical Production
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Metabolomics in Animal Cell Culture
inferred← citeshttps://doi.org/10.1007/978-3-319-47656-8_2openalex-snapshot
Collection and Preparation of Clinical Samples for Metabolomics
inferred← citeshttps://doi.org/10.1007/s00018-017-2582-1openalex-snapshot
Experimental design and reporting standards for metabolomics studies of mammalian cell lines
inferred← citeshttps://doi.org/10.1007/s00253-013-5329-4openalex-snapshot
Changes in intracellular metabolite pools during growth of adherent MDCK cells in two different media
inferred← citeshttps://doi.org/10.1007/s00253-019-10048-1openalex-snapshot
Systems biology approach in the formulation of chemically defined media for recombinant protein overproduction
inferred← citeshttps://doi.org/10.1007/s00396-013-3093-8openalex-snapshot
Highly robust protein production by co-culture of CHO spheroids layered on feeder cells in serum-free medium
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Enhancement of ascomycin production in Streptomyces hygroscopicus var. ascomyceticus by combining resin HP20 addition and metabolic profiling analysis
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Comparative metabolic profiling reveals the key role of amino acids metabolism in the rapamycin overproduction by Streptomyces hygroscopicus
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Comparative metabolomics reveals the mechanism of avermectin production enhancement by S-adenosylmethionine
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A novel method based on nonparametric regression with a Gaussian kernel algorithm identifies the critical components in CHO media and feed optimization
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Sodium butyrate enhances the acidic isoform content of recombinant human erythropoietin produced by Chinese hamster ovary cells
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The enhancement of antibody concentration and achievement of high cell density CHO cell cultivation by adding nucleoside
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Early integration of Design of Experiment (DOE) and multivariate statistics identifies feeding regimens suitable for CHO cell line development and screening
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Comparative metabolomics analysis of the key metabolic nodes in propionic acid synthesis in Propionibacterium acidipropionici
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Cell line dependence of metabolite leakage in metabolome analyses of adherent normal and cancer cell lines
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Mitochondrial aconitase is a key regulator of energy production for growth and protein expression in Chinese hamster ovary cells
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Disruption of TCA Cycle and Glutamate Metabolism Identified by Metabolomics in an In Vitro Model of Amyotrophic Lateral Sclerosis
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Comparative metabolomics reveals specific metabolic signatures in colorectal cancer cell line models
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Recombinant Antibody Production in CHO and NS0 Cells: Differences and Similarities
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Quantitative NMR analysis of intra- and extracellular metabolism of mammalian cells: A tutorial
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GC-MS based metabolomics of colon cancer cells using different extraction solvents
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Coupled cell morphology investigation and metabolomics analysis improves rapamycin production in Streptomyces hygroscopicus
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High-throughput LC-MS quantitation of cell culture metabolites
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n-Hexadecane and pyrene biodegradation and metabolization by Rhodococcus sp. T1 isolated from oil contaminated soil
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Chemometric identification of canonical metabolites linking critical process parameters to monoclonal antibody production during bioprocess development
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The emerging CHO systems biology era: harnessing the ‘omics revolution for biotechnology
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Enhancement of production of protein biopharmaceuticals by mammalian cell cultures: the metabolomics perspective
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Biological insights through nontargeted metabolomics
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The emerging role of systems biology for engineering protein production in CHO cells
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What can mathematical modelling say about CHO metabolism and protein glycosylation?
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Metabolic analysis of antibody producing Chinese hamster ovary cell culture under different stresses conditions
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The influence of cell growth and enzyme activity changes on intracellular metabolite dynamics in AGE1.HN.AAT cells
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Reduced quenching and extraction time for mammalian cells using filtration and syringe extraction
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An omics approach to rational feed
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Therapeutic glycoprotein production in mammalian cells
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Coupling metabolomics analysis and DOE optimization strategy towards enhanced IBDV production by chicken embryo fibroblast DF-1 cells
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Metabolomics of adherent mammalian cells by capillary electrophoresis-mass spectrometry: HT-29 cells as case study
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Optimization of metabolomics pretreatment method of cholangiocarcinoma cells based on ultrahigh performance liquid chromatography coupled with mass spectrometry
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Application of hybrid cybernetic model in simulating myeloma cell culture co-consuming glucose and glutamine with mixed consumption patterns
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Liquid chromatography–high-resolution mass spectrometry-based cell metabolomics: Experimental design, recommendations, and applications
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Metabolic profiling reveals that time related physiological changes in mammalian cell perfusion cultures are bioreactor scale independent
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Microarray-based MALDI-TOF mass spectrometry enables monitoring of monoclonal antibody production in batch and perfusion cell cultures
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In Situ Analysis of Small Populations of Adherent Mammalian Cells Using Laser Ablation Electrospray Ionization Mass Spectrometry in Transmission Geometry
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Compartmentalized Proteomic Profiling Outlines the Crucial Role of the Classical Secretory Pathway during Recombinant Protein Production in Chinese Hamster Ovary Cells
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Factors Causing Compositional Changes in Soy Protein Hydrolysates and Effects on Cell Culture Functionality
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Comparative Metabolomic-Based Metabolic Mechanism Hypothesis for Microbial Mixed Cultures Utilizing Cane Molasses Wastewater for Higher 2-Phenylethanol Production
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Application of Multi-Omics Techniques for Bioprocess Design and Optimization in Chinese Hamster Ovary Cells
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Evolution from adherent to suspension: systems biology of HEK293 cell line development
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Multiplex genome editing eliminates lactate production without impacting growth rate in mammalian cells
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Effects of culture media on metabolic profiling of the human gastric cancer cell line SGC7901
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GC-MS profiling of leukemia cells: an optimized preparation protocol for the intracellular metabolome
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Medium optimization based on comparative metabolomic analysis of chicken embryo fibroblast DF-1 cells
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Comprehensive stable-isotope tracing of glucose and amino acids identifies metabolic by-products and their sources in CHO cell culture
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Systems biology and metabolic modelling unveils limitations to polyhydroxybutyrate accumulation in sugarcane leaves; lessons for C 4 engineering
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Integrated intracellular metabolic profiling and pathway analysis approaches reveal complex metabolic regulation by Clostridium acetobutylicum
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Linking genotype and phenotype in an economically viable propionic acid biosynthesis process
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Omics-based analyses revealed metabolic responses of Clostridium acetobutylicum to lignocellulose-derived inhibitors furfural, formic acid and phenol stress for butanol fermentation
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Improving recombinant protein productivity in CHO cells via multi-omics data integration
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Recombinant expression systems
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1H NMR Spectroscopy Profiling of Metabolic Reprogramming of Chinese Hamster Ovary Cells upon a Temperature Shift during Culture
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WITHDRAWN
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The regulation of glutaminolysis and citric acid cycle activity during mammalian cell cultivation
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Metabolomics and Network Biology for sensitive monitoring of how growth environment changes affect the physiology of industrial-scale perfusion cultures
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Using Metabolomics to Identify Cell Line-Independent Indicators of Growth Inhibition for Chinese Hamster Ovary Cell-Based Bioprocesses
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Advances in Mammalian Cell Line Development Technologies for Recombinant Protein Production
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Metabolic-sensing characteristics of absorption-photometry for mammalian cell cultures in biopharmaceutical processes
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The application of omics in pharmaceutical bioprocessing
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Insights on biomarkers from Chinese hamster ovary ‘omics’ studies
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Industry perspective on Chinese hamster ovary cell ‘omics’
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Statistical methods for mining Chinese hamster ovary cell ‘omics data: from differential expression to integrated multilevel analysis of the biological system
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A high-throughput media design approach for high performance mammalian fed-batch cultures
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