On the public citation graph

A Step toward NRF2‐DNA Interaction Inhibitors by Fragment‐Based NMR Methods

https://doi.org/10.1002/cmdc.202100458

0 signed · 86 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1096-987x(199604)17:5/6<490::aid-jcc1>3.0.co;2-popenalex-snapshot

Merck molecular force field. I. Basis, form, scope, parameterization, and performance of MMFF94

inferredcites →https://doi.org/10.1002/ange.201201358openalex-snapshot

Discovery of Small Molecules that Bind to K‐Ras and Inhibit Sos‐Mediated Activation

inferredcites →https://doi.org/10.1002/anie.201201358openalex-snapshot

Discovery of Small Molecules that Bind to K‐Ras and Inhibit Sos‐Mediated Activation

inferredcites →https://doi.org/10.1002/cmdc.202100458openalex-snapshot

A Step toward NRF2‐DNA Interaction Inhibitors by Fragment‐Based NMR Methods

inferredcites →https://doi.org/10.1002/pro.2201openalex-snapshot

Halogen bonding (X‐bonding): A biological perspective

inferredcites →https://doi.org/10.1002/prot.10299openalex-snapshot

Refinement of protein structures in explicit solvent

inferredcites →https://doi.org/10.1002/prot.21929openalex-snapshot

Probing electric fields in proteins in solution by NMR spectroscopy

inferredcites →https://doi.org/10.1007/bf00197633openalex-snapshot

Calibration of ring-current effects in proteins and nucleic acids

inferredcites →https://doi.org/10.1007/bf00197809openalex-snapshot

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

inferredcites →https://doi.org/10.1007/s00894-006-0130-2openalex-snapshot

Halogen bonding: the σ-hole

inferredcites →https://doi.org/10.1007/s10858-013-9741-yopenalex-snapshot

Protein backbone and sidechain torsion angles predicted from NMR chemical shifts using artificial neural networks

inferredcites →https://doi.org/10.1007/s10858-016-0060-yopenalex-snapshot

CcpNmr AnalysisAssign: a flexible platform for integrated NMR analysis

inferredcites →https://doi.org/10.1016/j.chembiol.2014.09.001openalex-snapshot

Small-Molecule Inhibitors of Protein-Protein Interactions: Progressing toward the Reality

inferredcites →https://doi.org/10.1016/j.chembiol.2015.04.019openalex-snapshot

Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions

inferredcites →https://doi.org/10.1016/j.drudis.2011.02.002openalex-snapshot

Fragment screening to predict druggability (ligandability) and lead discovery success

inferredcites →https://doi.org/10.1016/j.drudis.2019.02.013openalex-snapshot

The next level in chemical space navigation: going far beyond enumerable compound libraries

inferredcites →https://doi.org/10.1016/j.freeradbiomed.2011.03.008openalex-snapshot

Luteolin inhibits Nrf2 leading to negative regulation of the Nrf2/ARE pathway and sensitization of human lung carcinoma A549 cells to therapeutic drugs

inferredcites →https://doi.org/10.1016/j.freeradbiomed.2014.11.009openalex-snapshot

Dual roles of NRF2 in tumor prevention and progression: Possible implications in cancer treatment

inferredcites →https://doi.org/10.1016/j.molcel.2006.01.013openalex-snapshot

Structural Basis for Defects of Keap1 Activity Provoked by Its Point Mutations in Lung Cancer

inferredcites →https://doi.org/10.1016/j.molmed.2020.01.004openalex-snapshot

Transcription Factor Inhibition: Lessons Learned and Emerging Targets

inferredcites →https://doi.org/10.1016/j.pnmrs.2013.02.001openalex-snapshot

Using chemical shift perturbation to characterise ligand binding

inferredcites →https://doi.org/10.1016/j.trecan.2015.07.001openalex-snapshot

Targeting Transcription Factors in Cancer

inferredcites →https://doi.org/10.1016/s0959-440x(02)00289-0openalex-snapshot

Coupling of folding and binding for unstructured proteins

inferredcites →https://doi.org/10.1021/acs.jctc.7b00125openalex-snapshot

The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design

inferredcites →https://doi.org/10.1021/acs.jmedchem.8b01048openalex-snapshot

Virtual Chemical Libraries

inferredcites →https://doi.org/10.1021/acs.jmedchem.8b01292openalex-snapshot

qFit-ligand Reveals Widespread Conformational Heterogeneity of Drug-Like Molecules in X-Ray Electron Density Maps

inferredcites →https://doi.org/10.1021/acschembio.5b00448openalex-snapshot

A Small Molecule Inhibits Deregulated NRF2 Transcriptional Activity in Cancer

inferredcites →https://doi.org/10.1021/acschembio.6b00651openalex-snapshot

Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors

inferredcites →https://doi.org/10.1021/cb500071vopenalex-snapshot

A Small Molecule Compound Targeting STAT3 DNA-Binding Domain Inhibits Cancer Cell Proliferation, Migration, and Invasion

inferredcites →https://doi.org/10.1021/ci049885eopenalex-snapshot

LigandScout: 3-D Pharmacophores Derived from Protein-Bound Ligands and Their Use as Virtual Screening Filters

inferredcites →https://doi.org/10.1021/ci400257kopenalex-snapshot

Halogen Interactions in Protein–Ligand Complexes: Implications of Halogen Bonding for Rational Drug Design

inferredcites →https://doi.org/10.1021/ci500446sopenalex-snapshot

Performance of Protein–Ligand Docking with Simulated Chemical Shift Perturbations

inferredcites →https://doi.org/10.1021/ci500487qopenalex-snapshot

Which Three-Dimensional Characteristics Make Efficient Inhibitors of Protein–Protein Interactions?

inferredcites →https://doi.org/10.1021/ci900188ropenalex-snapshot

Steering Protein−Ligand Docking with Quantitative NMR Chemical Shift Perturbations

inferredcites →https://doi.org/10.1021/ja026939xopenalex-snapshot

HADDOCK: A Protein−Protein Docking Approach Based on Biochemical or Biophysical Information

inferredcites →https://doi.org/10.1021/ja0737974openalex-snapshot

Rapid Protein−Ligand Costructures Using Chemical Shift Perturbations

inferredcites →https://doi.org/10.1021/jacs.8b11099openalex-snapshot

Interplay between Conformational Entropy and Solvation Entropy in Protein–Ligand Binding

inferredcites →https://doi.org/10.1021/jm049131ropenalex-snapshot

Druggability Indices for Protein Targets Derived from NMR-Based Screening Data

inferredcites →https://doi.org/10.1021/jm500802jopenalex-snapshot

Discovery of Small-Molecule Inhibitors Selectively Targeting the DNA-Binding Domain of the Human Androgen Receptor

inferredcites →https://doi.org/10.1021/jm701194ropenalex-snapshot

Determination of Protein–Ligand Binding Modes Using Complexation-Induced Changes in 1H NMR Chemical Shift

inferredcites →https://doi.org/10.1023/a:1026508025631openalex-snapshot

Alignment of weakly interacting molecules to protein surfaces using simulations of chemical shift perturbations

inferredcites →https://doi.org/10.1038/nature11404openalex-snapshot

Comprehensive genomic characterization of squamous cell lung cancers

inferredcites →https://doi.org/10.1038/ng.3564openalex-snapshot

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

inferredcites →https://doi.org/10.1038/nprot.2007.406openalex-snapshot

Version 1.2 of the Crystallography and NMR system

inferredcites →https://doi.org/10.1038/nrc906openalex-snapshot

Transcription factors as targets for cancer therapy

inferredcites →https://doi.org/10.1038/nrd.2016.109openalex-snapshot

Twenty years on: the impact of fragments on drug discovery

inferredcites →https://doi.org/10.1038/nrd1343openalex-snapshot

Small-molecule inhibitors of protein–protein interactions: progressing towards the dream

inferredcites →https://doi.org/10.1038/nsb0698-484openalex-snapshot

A new DNA-binding motif in the Skn-1 binding domain–DNA complex

inferredcites →https://doi.org/10.1038/s41568-019-0196-7openalex-snapshot

Targeting transcription factors in cancer — from undruggable to reality

inferredcites →https://doi.org/10.1038/s41586-019-0917-9openalex-snapshot

Ultra-large library docking for discovering new chemotypes

inferredcites →https://doi.org/10.1038/s41586-020-2027-0openalex-snapshot

Virtual discovery of melatonin receptor ligands to modulate circadian rhythms

inferredcites →https://doi.org/10.1063/1.1742701openalex-snapshot

Proton Magnetic Resonance of Hydrocarbons

inferredcites →https://doi.org/10.1073/pnas.1014275108openalex-snapshot

Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism

inferredcites →https://doi.org/10.1073/pnas.1116510109openalex-snapshot

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

inferredcites →https://doi.org/10.1073/pnas.1904529116openalex-snapshot

Drugging an undruggable pocket on KRAS

inferredcites →https://doi.org/10.1073/pnas.91.21.9926openalex-snapshot

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region.

inferredcites →https://doi.org/10.1073/pnas.95.15.8455openalex-snapshot

The solution structure of the DNA-binding domain of Skn-1

inferredcites →https://doi.org/10.1093/bioinformatics/btl589openalex-snapshot

ARIA2: Automated NOE assignment and data integration in NMR structure calculation

inferredcites →https://doi.org/10.1093/carcin/bgn095openalex-snapshot

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

inferredcites →https://doi.org/10.1107/s0907444904011679openalex-snapshot

PRODRG: a tool for high-throughput crystallography of protein–ligand complexes

inferredcites →https://doi.org/10.1107/s0907444998003254openalex-snapshot

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

inferredcites →https://doi.org/10.1111/j.1365-2443.2006.00965.xopenalex-snapshot

Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements

inferredcites →https://doi.org/10.1128/mcb.00708-09openalex-snapshot

Structural Basis of Alternative DNA Recognition by Maf Transcription Factors

inferredcites →https://doi.org/10.1139/v60-040openalex-snapshot

CHEMICAL SHIFTS IN THE NUCLEAR MAGNETIC RESONANCE SPECTRA OF MOLECULES CONTAINING POLAR GROUPS

inferredcites →https://doi.org/10.1146/annurev-pharmtox-010818-021856openalex-snapshot

Modulating NRF2 in Disease: Timing Is Everything

inferredcites →https://doi.org/10.1155/2019/8592348openalex-snapshot

Potential Applications of NRF2 Inhibitors in Cancer Therapy

inferredcites →https://doi.org/10.1158/0008-5472.can-18-2723openalex-snapshot

NRF2 Activation in Cancer: From DNA to Protein

inferredcites →https://doi.org/10.1186/1476-4598-12-124openalex-snapshot

Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer

inferredcites →https://doi.org/10.1186/s12964-019-0435-2openalex-snapshot

Dual roles and therapeutic potential of Keap1-Nrf2 pathway in pancreatic cancer: a systematic review

inferredcites →https://doi.org/10.1371/journal.pmed.0030420openalex-snapshot

Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer

inferredcites →https://doi.org/10.2210/pdb6dmj/pdbopenalex-snapshot

A multiconformer ligand model of inhibitor 53W bound to CREB binding protein bromodomain

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.3897/pharmacia.72.e167365zenodo-depositor-declared

Oxidative stress as a key factor in the pathophysiology of neurodegenerative diseases: molecular mechanisms and protection pathways – Review

inferred← citeshttps://doi.org/10.1002/ardp.202300649openalex-snapshot

Ligandability assessment of the C‐terminal Rel‐homology domain of NFAT1

inferred← citeshttps://doi.org/10.1007/978-3-031-76718-0_11openalex-snapshot

Ultra-Large-Scale Virtual Screening

inferred← citeshttps://doi.org/10.1007/s10787-025-01985-7openalex-snapshot

Nrf2 signaling in bone health: unlocking new avenues for osteoporosis management

inferred← citeshttps://doi.org/10.1007/s12272-025-01557-xopenalex-snapshot

NRF2 activation in cancer and overview of NRF2 small molecule inhibitors

inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2022.09.023openalex-snapshot

The current status and future prospects for therapeutic targeting of KEAP1-NRF2 and β-TrCP-NRF2 interactions in cancer chemoresistance

inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.142273openalex-snapshot

Role of acetate/benzoate substituents on the anticancer activities, in vitro and in silico DNA/BSA interactions of new 1,4-disubstituted 1,2,3-triazole derivatives

inferred← citeshttps://doi.org/10.1021/acs.jcim.2c00224openalex-snapshot

Exploration of Ultralarge Compound Collections for Drug Discovery

inferred← citeshttps://doi.org/10.1021/acs.jcim.6c01496openalex-snapshot

Strategies for Identifying Molecules of Interest in Large Chemical Spaces

inferred← citeshttps://doi.org/10.1080/15376516.2026.2691542openalex-snapshot

Comprehensive assessment of hyperoside: cytotoxic, anti-cancer, genoprotective, radical scavenging and computational toxicity properties through in vitro and in silico approaches

inferred← citeshttps://doi.org/10.1101/2025.08.18.670902openalex-snapshot

Pyrimethamine inhibits mutant NRF2 as a molecular glue

inferred← citeshttps://doi.org/10.3390/biom16060828openalex-snapshot

Genotypic and Phenotypic Diversity as a Function of CRISPR-Directed Gene Knock-Out of NRF2 in Pancreatic Adenocarcinoma Cells, a Feasibility Study

inferred← citeshttps://doi.org/10.3390/cancers18091354openalex-snapshot

Pyrimethamine Restores KEAP1-Mediated Degradation of Select NRF2 Mutants in Esophageal Squamous Cell Carcinoma

inferred← citeshttps://doi.org/10.3390/cimb48020171openalex-snapshot

Investigating Potential 5′ UTR G-Quadruplexes Within NRF2 mRNA

showing the first 14 of 15 · page through all 15

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.