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Digestive fate of dietary carrageenan: Evidence of interference with digestive proteolysis and disruption of gut epithelial function
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1 of the 56 references listed on this page is in the Retraction Watch database as retracted (export 2026-11-04): 10.1016/j.carbpol.2014.01.067 (notice 2016-10-20).
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dataset doi:10.7910/DVN/WT8VOA (CC BY 4.0).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.fct.2014.12.022openalex-snapshotAn infant formula toxicity and toxicokinetic feeding study on carrageenan in preweaning piglets with special attention to the immune system and gastrointestinal tract
inferredcites →https://doi.org/10.1016/j.toxlet.2012.04.012openalex-snapshotPro-inflammatory NF-κB and early growth response gene 1 regulate epithelial barrier disruption by food additive carrageenan in human intestinal epithelial cells
inferredcites →https://doi.org/10.1021/jf048174dopenalex-snapshotAngiotensin I Converting Enzyme Inhibitory Peptides from In Vitro Pepsin−Pancreatin Digestion of Soy Protein
inferredcites →https://doi.org/10.1038/361552a0openalex-snapshotUncoupling of the molecular 'fence' and paracellular 'gate' functions in epithelial tight junctions
inferredcites →https://doi.org/10.1038/ajg.2013.46openalex-snapshotAn Altered Gut Microbiome Profile in a Child Affected by Crohn's Disease Normalized After Nutritional Therapy
inferredcites →https://doi.org/10.1039/c4fo01165aopenalex-snapshotAntioxidant activity of bovine alpha lactalbumin Maillard products and evaluation of their in vitro gastro-duodenal digestive proteolysis
inferredcites →https://doi.org/10.1074/jbc.m708833200openalex-snapshotToll-like Receptor 4 Mediates Induction of the Bcl10-NFκB-Interleukin-8 Inflammatory Pathway by Carrageenan in Human Intestinal Epithelial Cells
inferredcites →https://doi.org/10.1080/20024091064282openalex-snapshotA Critical Review of the Toxicological Effects of Carrageenan and Processed Eucheuma Seaweed on the Gastrointestinal Tract
inferredcites →https://doi.org/10.2741/3888openalex-snapshotMolecular regulation of the intestinal epithelial barrier: implication in human diseases
inferredcites →https://doi.org/10.3109/10408444.2013.861797openalex-snapshotFood additive carrageenan: Part I: A critical review of carrageenanin vitrostudies, potential pitfalls, and implications for human health and safety
inferredcites →https://doi.org/10.3382/ps.2008-00485openalex-snapshotEffect of different concentrations of calcium chloride and potassium chloride on egg white proteins during isoelectric precipitation of ovomucin
inferredcites →https://doi.org/10.3390/nu7031565openalex-snapshotEffect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity
inferredcites →https://doi.org/10.3892/mmr.2013.1726openalex-snapshotκ-carrageenan induces the disruption of intestinal epithelial Caco-2 monolayers by promoting the interaction between intestinal epithelial cells and immune cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1016/j.carres.2025.109764openalex-snapshotToward sustainable, smart, and multifunctional Carrageenan bio(nano)composites: Mechanistic insights, physicochemical properties, biomedical interfaces, and AI-driven design perspectives
inferred← citeshttps://doi.org/10.1016/j.cirep.2025.200224openalex-snapshotThe effect of corn starch and Kappa-Carrageenan probiotic encapsulation on growth and immune response in Chinook salmon (Oncorhynchus tshawytscha)
inferred← citeshttps://doi.org/10.1016/j.crfs.2026.101418openalex-snapshotHigh-sugar and carrageenan-containing diets synergistically impair the intestinal mucosal barrier through the gut microbiota: in vitro and in vivo studies
inferred← citeshttps://doi.org/10.1016/j.fct.2017.06.022openalex-snapshotAddendum to Weiner, M.L. (2016) Parameters and Pitfalls to Consider in the Conduct of Food Additive Research, Carrageenan as a Case Study. Food Chemical Toxicology 87, 31-44.
inferred← citeshttps://doi.org/10.1016/j.foodchem.2025.144633openalex-snapshotPreparation and evaluation of licochalcone A - integrated casein-pectin nanodelivery system: Insights into its gastrointestinal digestibility and bioavailability
inferred← citeshttps://doi.org/10.1016/j.foodhyd.2022.107553openalex-snapshotPhysicochemical dynamic changes and differences of κ-carrageenan in different vehicles (aqueous and casein solution) during in vitro gastrointestinal digestion
inferred← citeshttps://doi.org/10.1016/j.foodhyd.2022.107850openalex-snapshotAn in vitro digestion model accounting for sex differences in gastro-intestinal functions and its application to study differential protein digestibility
inferred← citeshttps://doi.org/10.1016/j.phrs.2021.105940openalex-snapshotλ-carrageenan exacerbates Citrobacter rodentium-induced infectious colitis in mice by targeting gut microbiota and intestinal barrier integrity
inferred← citeshttps://doi.org/10.1039/c7fo01721aopenalex-snapshotRevisiting the carrageenan controversy: do we really understand the digestive fate and safety of carrageenan in our foods?
inferred← citeshttps://doi.org/10.1039/c9fo00018fopenalex-snapshotReply to the Comment on “Revisiting the carrageenan controversy: do we really understand the digestive fate and safety of carrageenan in our foods?” by M. Weiner and J. McKim, Food Funct. , 2019, 10 : DOI: 10.1039/C8FO01282B
inferred← citeshttps://doi.org/10.1039/d4fo01418aopenalex-snapshotInfluence of consumption of the food additive carrageenan on the gut microbiota and the intestinal homeostasis of mice
inferred← citeshttps://doi.org/10.1080/10408444.2023.2270574openalex-snapshotEvidence and hypotheses on adverse effects of the food additives carrageenan (E 407)/processed Eucheuma seaweed (E 407a) and carboxymethylcellulose (E 466) on the intestines: a scoping review
inferred← citeshttps://doi.org/10.1093/ecco-jcc/jjaa254openalex-snapshotFood Additive Emulsifiers and Their Impact on Gut Microbiome, Permeability, and Inflammation: Mechanistic Insights in Inflammatory Bowel Disease
inferred← citeshttps://doi.org/10.1093/ibd/izz268openalex-snapshotDining With Inflammatory Bowel Disease: A Review of the Literature on Diet in the Pathogenesis and Management of IBD
inferred← citeshttps://doi.org/10.1093/nutrit/nuaa038openalex-snapshotFood additive emulsifiers: a review of their role in foods, legislation and classifications, presence in food supply, dietary exposure, and safety assessment
inferred← citeshttps://doi.org/10.1159/000548931openalex-snapshotEffectiveness of the Crohn’s Disease Exclusion Diet for the Treatment of Crohn’s Disease in the Older-Adult Population: Real-World Experience
inferred← citeshttps://doi.org/10.3168/jds.2018-14783openalex-snapshotMetabolic effects in mice of cream formulation: Addition of both thickener and emulsifier does not alter lipid metabolism but modulates mucus cells and intestinal endoplasmic reticulum stress
inferred← citeshttps://doi.org/10.3390/foods10010173openalex-snapshotFood and Beverages Containing Algae and Derived Ingredients Launched in the Market from 2015 to 2019: A Front-of-Pack Labeling Perspective with a Special Focus on Spain
inferred← citeshttps://doi.org/10.3390/foods15071131openalex-snapshotDifferential Effects of Commercial Food-Grade Carrageenan Preparations on DSS-Induced Colitis and Gut Microbiota in Mice
inferred← citeshttps://doi.org/10.3390/foods9091253openalex-snapshotAddition of Anionic Polysaccharide Stabilizers Modulates In Vitro Digestive Proteolysis of a Chocolate Milk Drink in Adults and Children
inferred← citeshttps://doi.org/10.3390/jcm12165428openalex-snapshotCrohn’s Disease Exclusion Diet for the Treatment of Crohn’s Disease: Real-World Experience from a Tertiary Center
inferred← citeshttps://doi.org/10.3390/nu11071498openalex-snapshotDiet in the Pathogenesis and Management of Ulcerative Colitis; A Review of Randomized Controlled Dietary Interventions
inferred← citeshttps://doi.org/10.3390/nu12072018openalex-snapshotDietary Strategies for Maintenance of Clinical Remission in Inflammatory Bowel Diseases: Are We There Yet?
inferred← citeshttps://doi.org/10.3390/nu12092827openalex-snapshotEmulsifiers Impact Colonic Length in Mice and Emulsifier Restriction is Feasible in People with Crohn’s Disease
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