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Effect of Wuzhi Tablet (Schisandra sphenanthera extract) on the Pharmacokinetics of Paclitaxel in Rats

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bdd.705openalex-snapshot
Enhancement of oral bioavailability of paclitaxel after oral administration of Schisandrol B in rats
inferredcites →https://doi.org/10.1002/bmc.1305openalex-snapshot
Study of the effect of Wuzhi tablet (Schisandra sphenanthera extract) on tacrolimus tissue distribution in rat by liquid chromatography tandem mass spectrometry method
inferredcites →https://doi.org/10.1002/jps.21827openalex-snapshot
Interactions between the flavonoid biochanin A and P-glycoprotein substrates in rats: In vitro and in vivo
inferredcites →https://doi.org/10.1007/s00280-001-0419-xopenalex-snapshot
P-glycoprotein inhibition by the multidrug resistance-reversing agent MS-209 enhances bioavailability and antitumor efficacy of orally administered paclitaxel
inferredcites →https://doi.org/10.1016/j.bbrc.2005.07.097openalex-snapshot
Schisandrin B—A novel inhibitor of P-glycoprotein
inferredcites →https://doi.org/10.1016/j.bmcl.2007.11.082openalex-snapshot
Antiproliferative effects of dibenzocyclooctadiene lignans isolated from Schisandra chinensis in human cancer cells
inferredcites →https://doi.org/10.1016/j.canlet.2006.03.009openalex-snapshot
Schisandrin B: A dual inhibitor of P-glycoprotein and multidrug resistance-associated protein 1
inferredcites →https://doi.org/10.1016/j.ejpb.2003.11.002openalex-snapshot
Enhanced paclitaxel bioavailability after oral administration of paclitaxel or prodrug to rats pretreated with quercetin
inferredcites →https://doi.org/10.1016/j.ejps.2004.10.002openalex-snapshot
The effect of verapamil on the pharmacokinetics of paclitaxel in rats
inferredcites →https://doi.org/10.1016/j.ijpharm.2006.05.046openalex-snapshot
Altered pharmacokinetics of paclitaxel by the concomitant use of morin in rats
inferredcites →https://doi.org/10.1016/j.ijpharm.2007.01.002openalex-snapshot
Effect of genistein on the pharmacokinetics of paclitaxel administered orally or intravenously in rats
inferredcites →https://doi.org/10.1016/j.ijpharm.2010.01.025openalex-snapshot
Mechanistic understanding of the different effects of Wuzhi Tablet (Schisandra sphenanthera extract) on the absorption and first-pass intestinal and hepatic metabolism of Tacrolimus (FK506)
inferredcites →https://doi.org/10.1016/s0378-5173(01)00986-3openalex-snapshot
Paclitaxel and its formulations
inferredcites →https://doi.org/10.1023/b:drug.0000026248.45084.21openalex-snapshot
Efficacy of novel P-glycoprotein inhibitors to increase the oral uptake of paclitaxel in mice
inferredcites →https://doi.org/10.1055/s-2007-967178openalex-snapshot
Effects of Schisandra Lignans on P-Glycoprotein-Mediated Drug Efflux in Human Intestinal Caco-2 Cells
inferredcites →https://doi.org/10.1073/pnas.94.5.2031openalex-snapshot
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
inferredcites →https://doi.org/10.1124/dmd.104.000646openalex-snapshot
IDENTIFICATION AND CHARACTERIZATION OF POTENT CYP3A4 INHIBITORS IN SCHISANDRA FRUIT EXTRACT
inferredcites →https://doi.org/10.1124/dmd.109.027433openalex-snapshot
Effects of Short-Term and Long-Term Pretreatment of Schisandra Lignans on Regulating Hepatic and Intestinal CYP3A in Rats
inferredcites →https://doi.org/10.3109/07357909509031919openalex-snapshot
Taxanes: A New Class of Antitumor Agents

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4492751openalex-extracted
Protection of Schisantherin a Against Dictamnine-Induced Hepatotoxicity Via Inhibiting the Metabolic Activation of Dictamnine
inferred← citeshttps://doi.org/10.1002/jat.4557openalex-snapshot
Protection of schisantherin A against dictamnine‐induced hepatotoxicity: Pharmacokinetic insights
inferred← citeshttps://doi.org/10.1002/ptr.4849openalex-snapshot
Effect of Wuzhi Tablet (Schisandra sphenanthera extract) on the Pharmacokinetics of Cyclosporin A in Rats
inferred← citeshttps://doi.org/10.1002/ptr.4867openalex-snapshot
Pharmacokinetics of Hesperetin and Naringenin in the Zhi Zhu Wan, a Traditional Chinese Medicinal Formulae, and its Pharmacodynamics Study
inferred← citeshttps://doi.org/10.1002/ptr.5395openalex-snapshot
Inhibition of UDP-Glucuronosyltransferases (UGTs) Activity by constituents of Schisandra chinensis
inferred← citeshttps://doi.org/10.1007/978-3-030-74779-4_6openalex-snapshot
Schisandra chinensis and Schisandra sphenanthera—From Traditional Far Eastern Medicine to International Utilization
inferred← citeshttps://doi.org/10.1007/s11101-018-9582-0openalex-snapshot
Phytochemical studies and biological activity of three Chinese Schisandra species (Schisandra sphenanthera, Schisandra henryi and Schisandra rubriflora): current findings and future applications
inferred← citeshttps://doi.org/10.1007/s40495-016-0062-1openalex-snapshot
A Molecular Aspect in the Regulation of Drug Metabolism: Does PXR-Induced Enzyme Expression Always Lead to Functional Changes in Drug Metabolism?
inferred← citeshttps://doi.org/10.1016/b978-0-12-811147-5.00012-1openalex-snapshot
Pharmacokinetic–Pharmacodynamic Study of Zhi Zhu Wan
inferred← citeshttps://doi.org/10.1016/b978-0-12-823975-9.00004-3openalex-snapshot
Drug metabolism and pharmacokinetic diversity of Taxus medicinal compounds
inferred← citeshttps://doi.org/10.1016/j.fitote.2012.08.004openalex-snapshot
Strong inhibition of deoxyschizandrin and schisantherin A toward UDP-glucuronosyltransferase (UGT) 1A3 indicating UGT inhibition-based herb–drug interaction
inferred← citeshttps://doi.org/10.1016/j.jchromb.2015.11.024openalex-snapshot
Transporter modulation by Chinese herbal medicines and its mediated pharmacokinetic herb–drug interactions
inferred← citeshttps://doi.org/10.1016/j.jep.2021.114759openalex-snapshot
A comprehensive review of ethnopharmacology, phytochemistry, pharmacology, and pharmacokinetics of Schisandra chinensis (Turcz.) Baill. and Schisandra sphenanthera Rehd. et Wils.
inferred← citeshttps://doi.org/10.1016/j.jpba.2015.01.001openalex-snapshot
Simultaneous determination of seven taxoids in rat plasma by UPLC–MS/MS and pharmacokinetic study after oral administration of Taxus yunnanensis extracts
inferred← citeshttps://doi.org/10.1016/j.jpba.2021.114360openalex-snapshot
UPLC-MS/MS method for the determination of Lenvatinib in rat plasma and its application to drug-drug interaction studies
inferred← citeshttps://doi.org/10.1016/j.phymed.2013.12.006openalex-snapshot
Effect of Tacrolimus on the pharmacokinetics of bioactive lignans of Wuzhi tablet (Schisandra sphenanthera extract) and the potential roles of CYP3A and P-gp
inferred← citeshttps://doi.org/10.1016/j.phymed.2015.03.003openalex-snapshot
Protective effect of Wuzhi tablet (Schisandra sphenanthera extract) against cisplatin-induced nephrotoxicity via Nrf2-mediated defense response
inferred← citeshttps://doi.org/10.1016/j.taap.2025.117644openalex-snapshot
Schisantherin A alleviates hepatotoxicity induced by diosbulbin B in mice via suppressing metabolic activation of diosbulbin B
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.5b00465openalex-snapshot
Development of in Silico Models for Predicting P-Glycoprotein Inhibitors Based on a Two-Step Approach for Feature Selection and Its Application to Chinese Herbal Medicine Screening
inferred← citeshttps://doi.org/10.1080/10826076.2013.853309openalex-snapshot
STUDY ON ACTIVE INGREDIENTS OF LIGNANS FROM SCHISANDRA CHINENSIS BASED ON HOLLOW FIBER LIQUID PHASE MICROEXTRACTION
inferred← citeshttps://doi.org/10.1080/17512433.2022.2045193openalex-snapshot
Effect of Wuzhi capsules on cyclosporine A concentration in children with aplastic anemia immunotherapy: a single-center observational study
inferred← citeshttps://doi.org/10.1124/dmd.112.050302openalex-snapshot
Effects of Traditional Chinese Medicine Wuzhi Capsule on Pharmacokinetics of Tacrolimus in Rats
inferred← citeshttps://doi.org/10.1124/dmd.113.053892openalex-snapshot
In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
inferred← citeshttps://doi.org/10.1124/dmd.114.059535openalex-snapshot
Wuzhi Tablet (Schisandra Sphenanthera Extract) Protects against Acetaminophen-Induced Hepatotoxicity by Inhibition of CYP-Mediated Bioactivation and Regulation of NRF2-ARE and p53/p21 Pathways
inferred← citeshttps://doi.org/10.1139/y2012-080openalex-snapshot
A study about drug combination therapy ofSchisandra sphenantheraextract and Rapamycin in healthy subjects
inferred← citeshttps://doi.org/10.1155/2016/5614747openalex-snapshot
Effects of Jia‐Wei‐Xiao‐Yao‐San on the Peripheral and Lymphatic Pharmacokinetics of Paclitaxel in Rats
inferred← citeshttps://doi.org/10.1186/s13020-024-00879-0openalex-snapshot
Comprehensive review of dibenzocyclooctadiene lignans from the Schisandra genus: anticancer potential, mechanistic insights and future prospects in oncology
inferred← citeshttps://doi.org/10.1586/erm.12.126openalex-snapshot
Theranostics meets traditional Chinese medicine: rational prediction of drug–herb interactions
inferred← citeshttps://doi.org/10.21037/jgo-22-174openalex-snapshot
Influence of schisantherin A on the pharmacokinetics of lenvatinib in rats and its potential mechanism
inferred← citeshttps://doi.org/10.3109/03602532.2012.753902openalex-snapshot
Nuclear receptors in herb–drug interactions
inferred← citeshttps://doi.org/10.3109/03602532.2015.1124888openalex-snapshot
Pharmacokinetic herb–drug interactions with traditional Chinese medicine: progress, causes of conflicting results and suggestions for future research
inferred← citeshttps://doi.org/10.3389/fphar.2022.816036openalex-snapshot
A Comprehensive Review of the Main Lignan Components of Schisandra chinensis (North Wu Wei Zi) and Schisandra sphenanthera (South Wu Wei Zi) and the Lignan-Induced Drug-Drug Interactions Based on the Inhibition of Cytochrome P450 and P-Glycoprotein Activities
inferred← citeshttps://doi.org/10.3390/molecules28114333openalex-snapshot
Schisandra henryi—A Rare Species with High Medicinal Potential
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