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Effect of Wuzhi Tablet (Schisandra sphenanthera extract) on the Pharmacokinetics of Cyclosporin A in Rats

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bdd.705openalex-snapshot
Enhancement of oral bioavailability of paclitaxel after oral administration of Schisandrol B in rats
inferredcites →https://doi.org/10.1002/bmc.1305openalex-snapshot
Study of the effect of Wuzhi tablet (Schisandra sphenanthera extract) on tacrolimus tissue distribution in rat by liquid chromatography tandem mass spectrometry method
inferredcites →https://doi.org/10.1002/ptr.3407openalex-snapshot
Effect of Wuzhi Tablet (Schisandra sphenanthera extract) on the Pharmacokinetics of Paclitaxel in Rats
inferredcites →https://doi.org/10.1007/bf03259110openalex-snapshot
Erratum to: Cyclosporin: A Review of its Pharmacodynamic and Pharmacokinetic Properties, and Therapeutic Use in Immunoregulatory Disorders
inferredcites →https://doi.org/10.1016/j.bbrc.2005.07.097openalex-snapshot
Schisandrin B—A novel inhibitor of P-glycoprotein
inferredcites →https://doi.org/10.1016/j.biopha.2007.08.023openalex-snapshot
Fructus schisandrae (Wuweizi)-containing compound inhibits secretion of HBsAg and HBeAg in hepatocellular carcinoma cell line
inferredcites →https://doi.org/10.1016/j.canlet.2006.03.009openalex-snapshot
Schisandrin B: A dual inhibitor of P-glycoprotein and multidrug resistance-associated protein 1
inferredcites →https://doi.org/10.1016/j.ijpharm.2010.01.025openalex-snapshot
Mechanistic understanding of the different effects of Wuzhi Tablet (Schisandra sphenanthera extract) on the absorption and first-pass intestinal and hepatic metabolism of Tacrolimus (FK506)
inferredcites →https://doi.org/10.1046/j.1365-2125.2003.01759.xopenalex-snapshot
Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patients
inferredcites →https://doi.org/10.1055/s-2007-967178openalex-snapshot
Effects of Schisandra Lignans on P-Glycoprotein-Mediated Drug Efflux in Human Intestinal Caco-2 Cells
inferredcites →https://doi.org/10.1055/s-2007-981559openalex-snapshot
Composition and Biological Activity of Different Extracts from Schisandra sphenanthera and Schisandra chinensis
inferredcites →https://doi.org/10.1124/dmd.104.000646openalex-snapshot
IDENTIFICATION AND CHARACTERIZATION OF POTENT CYP3A4 INHIBITORS IN SCHISANDRA FRUIT EXTRACT
inferredcites →https://doi.org/10.1124/dmd.111.043018openalex-snapshot
Cyclosporine A- and Tacrolimus-Mediated Inhibition of CYP3A4 and CYP3A5 In Vitro
inferredcites →https://doi.org/10.2133/dmpk.21.122openalex-snapshot
Delayed Effect of Grapefruit Juice on Pharmacokinetics and Pharmacodynamics of Tacrolimus in a Living-Donor Liver Transplant Recipient
inferredcites →https://doi.org/10.2165/00003495-199345060-00007openalex-snapshot
Cyclosporin
inferredcites →https://doi.org/10.2165/00003495-199550050-00009openalex-snapshot
Cyclosporin
inferredcites →https://doi.org/10.2165/00003495-200161130-00006openalex-snapshot
Cyclosporin
inferredcites →https://doi.org/10.2174/157340807781369065openalex-snapshot
In Vivo Assessment of Cytochrome P450 3A4 and P-Glycoprotein Activity:Impact on Clinical Practice
inferredcites →https://doi.org/10.5414/cpp40451openalex-snapshot
Intake of grapefruit juice alters the metabolic pattern of cyclosporin A in renal transplant recipients

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4492751openalex-extracted
Protection of Schisantherin a Against Dictamnine-Induced Hepatotoxicity Via Inhibiting the Metabolic Activation of Dictamnine
inferred← citeshttps://doi.org/10.1002/9781118543436.ch97openalex-snapshot
Schisandra
inferred← citeshttps://doi.org/10.1002/9781119282594.ch4openalex-snapshot
Computational Toxicology for Traditional Chinese Medicine
inferred← citeshttps://doi.org/10.1007/978-3-030-74779-4_6openalex-snapshot
Schisandra chinensis and Schisandra sphenanthera—From Traditional Far Eastern Medicine to International Utilization
inferred← citeshttps://doi.org/10.1007/s11101-018-9582-0openalex-snapshot
Phytochemical studies and biological activity of three Chinese Schisandra species (Schisandra sphenanthera, Schisandra henryi and Schisandra rubriflora): current findings and future applications
inferred← citeshttps://doi.org/10.1016/j.ctim.2024.103017openalex-snapshot
Evidence of the interactions between immunosuppressive drugs used in autoimmune rheumatic diseases and Chinese herbal medicine: A scoping review
inferred← citeshttps://doi.org/10.1016/j.dmd.2026.100321openalex-snapshot
Potential herb-drug interaction risk of Sedum sarmentosum Bunge extract and cyclosporine A
inferred← citeshttps://doi.org/10.1016/j.jchromb.2015.11.024openalex-snapshot
Transporter modulation by Chinese herbal medicines and its mediated pharmacokinetic herb–drug interactions
inferred← citeshttps://doi.org/10.1016/j.jep.2021.114759openalex-snapshot
A comprehensive review of ethnopharmacology, phytochemistry, pharmacology, and pharmacokinetics of Schisandra chinensis (Turcz.) Baill. and Schisandra sphenanthera Rehd. et Wils.
inferred← citeshttps://doi.org/10.1016/j.jff.2021.104799openalex-snapshot
Schisandra chinensis polysaccharide protects against cyclosporin A-induced liver injury by promoting hepatocyte proliferation
inferred← citeshttps://doi.org/10.1016/j.jpba.2015.01.001openalex-snapshot
Simultaneous determination of seven taxoids in rat plasma by UPLC–MS/MS and pharmacokinetic study after oral administration of Taxus yunnanensis extracts
inferred← citeshttps://doi.org/10.1016/j.jpba.2021.114360openalex-snapshot
UPLC-MS/MS method for the determination of Lenvatinib in rat plasma and its application to drug-drug interaction studies
inferred← citeshttps://doi.org/10.1016/j.phymed.2013.04.005openalex-snapshot
In vitro to in vivo evidence of the inhibitor characteristics of Schisandra lignans toward P-glycoprotein
inferred← citeshttps://doi.org/10.1016/j.prostaglandins.2024.106813openalex-snapshot
Protective effect of misoprostol against paclitaxel-induced cardiac damage in rats
inferred← citeshttps://doi.org/10.1016/j.taap.2025.117644openalex-snapshot
Schisantherin A alleviates hepatotoxicity induced by diosbulbin B in mice via suppressing metabolic activation of diosbulbin B
inferred← citeshttps://doi.org/10.1016/j.tice.2022.101966openalex-snapshot
Protective potential of misoprostol against kidney alteration via alleviating oxidative stress in rat following exposure to paclitaxel
inferred← citeshttps://doi.org/10.1080/17512433.2022.2045193openalex-snapshot
Effect of Wuzhi capsules on cyclosporine A concentration in children with aplastic anemia immunotherapy: a single-center observational study
inferred← citeshttps://doi.org/10.1097/ftd.0000000000000875openalex-snapshot
Therapeutic Drug Monitoring and Pharmacokinetic Analysis of Cyclosporine in a Pediatric Patient with Hemophagocytic Lymphohistiocytosis Complicated by Diabetes Insipidus: A Grand Round
inferred← citeshttps://doi.org/10.1124/dmd.113.053892openalex-snapshot
In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
inferred← citeshttps://doi.org/10.1124/dmd.114.059535openalex-snapshot
Wuzhi Tablet (Schisandra Sphenanthera Extract) Protects against Acetaminophen-Induced Hepatotoxicity by Inhibition of CYP-Mediated Bioactivation and Regulation of NRF2-ARE and p53/p21 Pathways
inferred← citeshttps://doi.org/10.1124/dmd.117.076737openalex-snapshot
Wuzhi Tablet (Schisandra sphenanthera Extract) Is a Promising Tacrolimus-Sparing Agent for Renal Transplant Recipients Who Are CYP3A5 Expressers: a Two-Phase Prospective Study
inferred← citeshttps://doi.org/10.1142/s0192415x21500749openalex-snapshot
Schisandra sphenanthera: A Comprehensive Review of its Botany, Phytochemistry, Pharmacology, and Clinical Applications
inferred← citeshttps://doi.org/10.1155/2013/953520openalex-snapshot
Effects ofNigella sativaandLepidium sativumon Cyclosporine Pharmacokinetics
inferred← citeshttps://doi.org/10.1186/s13020-024-00879-0openalex-snapshot
Comprehensive review of dibenzocyclooctadiene lignans from the Schisandra genus: anticancer potential, mechanistic insights and future prospects in oncology
inferred← citeshttps://doi.org/10.1186/s13020-025-01096-zopenalex-snapshot
A comprehensive review of Schisandra chinensis lignans: pharmacokinetics, pharmacological mechanisms, and future prospects in disease prevention and treatment
inferred← citeshttps://doi.org/10.1208/s12249-019-1444-6openalex-snapshot
The Pharmacokinetic Prediction of Cyclosporin A after Coadministration with Wuzhi Capsule
inferred← citeshttps://doi.org/10.1371/journal.pone.0098717openalex-snapshot
Pharmacokinetic Compatibility of Ginsenosides and Schisandra Lignans in Shengmai-san: From the Perspective of P-Glycoprotein
inferred← citeshttps://doi.org/10.21037/jgo-22-174openalex-snapshot
Influence of schisantherin A on the pharmacokinetics of lenvatinib in rats and its potential mechanism
inferred← citeshttps://doi.org/10.2147/dddt.s364234openalex-snapshot
Effects of Ethanolic Extract of Schisandra sphenanthera on the Pharmacokinetics of Rosuvastatin in Rats
inferred← citeshttps://doi.org/10.2147/dddt.s89876openalex-snapshot
Pharmacokinetic and nephroprotective benefits of using Schisandra chinensis extracts in a cyclosporine A-based immune-suppressive regime
inferred← citeshttps://doi.org/10.2174/1389200224666230116113240openalex-snapshot
Herb-Drug Interactions and Their Impact on Pharmacokinetics: An Update
inferred← citeshttps://doi.org/10.3109/03602532.2015.1124888openalex-snapshot
Pharmacokinetic herb–drug interactions with traditional Chinese medicine: progress, causes of conflicting results and suggestions for future research
inferred← citeshttps://doi.org/10.3389/fphar.2022.816036openalex-snapshot
A Comprehensive Review of the Main Lignan Components of Schisandra chinensis (North Wu Wei Zi) and Schisandra sphenanthera (South Wu Wei Zi) and the Lignan-Induced Drug-Drug Interactions Based on the Inhibition of Cytochrome P450 and P-Glycoprotein Activities
inferred← citeshttps://doi.org/10.3389/fphar.2024.1344369openalex-snapshot
Pharmacokinetic assessment of tacrolimus in combination with deoxyschizandrin in rats
inferred← citeshttps://doi.org/10.3389/fvets.2022.940472openalex-snapshot
Pharmacokinetics and bioequivalence of two cyclosporine oral solution formulations in cats
inferred← citeshttps://doi.org/10.3390/ijms26010003openalex-snapshot
The Potential of Naturally Derived Compounds for Treating Chronic Kidney Disease: A Review of Autophagy and Cellular Senescence
inferred← citeshttps://doi.org/10.3390/molecules28114333openalex-snapshot
Schisandra henryi—A Rare Species with High Medicinal Potential
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