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Protection of Schisantherin a Against Dictamnine-Induced Hepatotoxicity Via Inhibiting the Metabolic Activation of Dictamnine

https://doi.org/10.2139/ssrn.4492751
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inferredcites →https://doi.org/10.1002/jssc.201600980openalex-extracted
Characterization of an epoxide‐derived metabolite of dictamnine using high‐performance liquid chromatography with hybrid linear trap quadrupole orbitrap mass spectrometry
inferredcites →https://doi.org/10.1002/ptr.3407openalex-extracted
Effect of Wuzhi Tablet (Schisandra sphenanthera extract) on the Pharmacokinetics of Paclitaxel in Rats
inferredcites →https://doi.org/10.1002/ptr.4849openalex-extracted
Effect of Wuzhi Tablet (Schisandra sphenanthera extract) on the Pharmacokinetics of Cyclosporin A in Rats
inferredcites →https://doi.org/10.1016/j.apsb.2017.04.002openalex-extracted
Schisandra sphenanthera extract (Wuzhi Tablet) protects against chronic-binge and acute alcohol-induced liver injury by regulating the NRF2-ARE pathway in mice
inferredcites →https://doi.org/10.1016/j.bcp.2019.113673openalex-extracted
Schisantherin A induces cell apoptosis through ROS/JNK signaling pathway in human gastric cancer cells
inferredcites →https://doi.org/10.1016/j.cbi.2015.02.022openalex-extracted
Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation
inferredcites →https://doi.org/10.1016/j.cbi.2018.09.014openalex-extracted
Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways
inferredcites →https://doi.org/10.1016/j.chroma.2006.01.077openalex-extracted
Pressurized liquid extraction followed by high-performance liquid chromatography for determination of seven active compounds in Cortex Dictamni
inferredcites →https://doi.org/10.1016/j.etap.2021.103628openalex-extracted
Biotransformation patterns of dictamnine in vitro/in vivo and its relative molecular mechanism of dictamnine-induced acute liver injury in mice
inferredcites →https://doi.org/10.1016/j.fct.2015.06.004openalex-extracted
Systematic review on herb-induced liver injury in Korea
inferredcites →https://doi.org/10.1016/j.fitote.2013.07.023openalex-extracted
Degraded limonoids and quinoline alkaloids from Dictamnus angustifolius G. Don ex Sweet. and their anti-platelet aggregation activity
inferredcites →https://doi.org/10.1016/j.fitote.2017.03.010openalex-extracted
Inhibition of human CYP3A4 and CYP3A5 enzymes by gomisin C and gomisin G, two lignan analogs derived from Schisandra chinensis
inferredcites →https://doi.org/10.1016/j.jchromb.2013.03.018openalex-extracted
Simultaneous determination of limonin, dictamnine, obacunone and fraxinellone in rat plasma by a validated UHPLC–MS/MS and its application to a pharmacokinetic study after oral administration of Cortex Dictamni extract
inferredcites →https://doi.org/10.1016/j.jep.2008.04.020openalex-extracted
Pharmacology of Schisandra chinensis Bail.: An overview of Russian research and uses in medicine
inferredcites →https://doi.org/10.1016/j.jep.2010.06.038openalex-extracted
Integral pharmacokinetics of multiple lignan components in normal, CCl4-induced hepatic injury and hepatoprotective agents pretreated rats and correlations with hepatic injury biomarkers
inferredcites →https://doi.org/10.1016/j.jep.2015.05.053openalex-extracted
Medicinal uses, phytochemistry and pharmacology of the genus Dictamnus (Rutaceae)
inferredcites →https://doi.org/10.1016/j.jep.2017.08.020openalex-extracted
Schisandra chinensis extract decreases chloroacetaldehyde production in rats and attenuates cyclophosphamide toxicity in liver, kidney and brain
inferredcites →https://doi.org/10.1016/j.jep.2019.112103openalex-extracted
Lignans from Schisandra sphenanthera protect against lithocholic acid-induced cholestasis by pregnane X receptor activation in mice
inferredcites →https://doi.org/10.1016/j.jpba.2015.11.016openalex-extracted
Metabolism of dictamnine in liver microsomes from mouse, rat, dog, monkey, and human
inferredcites →https://doi.org/10.1016/j.phymed.2012.11.008openalex-extracted
Effect of long-term co-administration of Wuzhi tablet (Schisandra sphenanthera extract) and prednisone on the pharmacokinetics of tacrolimus
inferredcites →https://doi.org/10.1016/j.phymed.2021.153609openalex-extracted
Schisantherin A ameliorates liver fibrosis through TGF-β1mediated activation of TAK1/MAPK and NF-κB pathways in vitro and in vivo
inferredcites →https://doi.org/10.1016/j.taap.2018.12.012openalex-extracted
Dictamnine-induced hepatotoxicity in mice: the role of metabolic activation of furan
inferredcites →https://doi.org/10.1016/j.toxlet.2020.05.004openalex-extracted
Cortex dictamni-induced liver injury in mice: The role of P450-mediated metabolic activation of furanoids
inferredcites →https://doi.org/10.1016/j.toxlet.2022.01.001openalex-extracted
The protein adduction derived from reactive metabolites of multiple furanoids in cortex Dictamni-treated mice
inferredcites →https://doi.org/10.1016/s1665-2681(19)30796-3openalex-extracted
Traditional Chinese Medicine and herbal hepatotoxicity: a tabular compilation of reported cases
inferredcites →https://doi.org/10.1055/s-2000-11202openalex-extracted
Improvement of Phase I Drug Metabolism with Schisandra chinensis Against CCl4 Hepatotoxicity in a Rat Model
inferredcites →https://doi.org/10.1089/jmf.2013.2849openalex-extracted
Schisandra chinensis Prevents Alcohol-Induced Fatty Liver Disease in Rats
inferredcites →https://doi.org/10.1097/00042737-200205000-00015openalex-extracted
Hepatitis associated with Chinese herbs
inferredcites →https://doi.org/10.1124/dmd.104.000646openalex-extracted
IDENTIFICATION AND CHARACTERIZATION OF POTENT CYP3A4 INHIBITORS IN SCHISANDRA FRUIT EXTRACT
inferredcites →https://doi.org/10.1124/dmd.112.050302openalex-extracted
Effects of Traditional Chinese Medicine Wuzhi Capsule on Pharmacokinetics of Tacrolimus in Rats
inferredcites →https://doi.org/10.19540/j.cnki.cjcmm.2017.0015openalex-extracted
[Dictamni Cortex powder-induced liver injury based on integrated evidence chain].
inferredcites →https://doi.org/10.3109/13880209.2014.890232openalex-extracted
The protective mechanism of schisandrin A in d -galactosamine-induced acute liver injury through activation of autophagy
inferredcites →https://doi.org/10.3389/fphar.2018.01033openalex-extracted
The Modulatory Role of CYP3A4 in Dictamnine-Induced Hepatotoxicity
inferredcites →https://doi.org/10.3390/molecules23102486openalex-extracted
Subchronic Toxicity Studies of Cortex Dictamni Extracts in Mice and Its Potential Hepatotoxicity Mechanisms in Vitro
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