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The role of metabolism in chondrocyte dysfunction and the progression of osteoarthritis
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Osteoarthritis chondrocytes die by apoptosis: A possible pathway for osteoarthritis pathology
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Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis
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Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis
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Mitochondrial DNA damage and reactive oxygen species in neurodegenerative disease
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Prevalence of nuclear and mitochondrial DNA mutations related to adult mitochondrial disease
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Acidic cysteine endoproteinase cathepsin K in the degeneration of the superficial articular hyaline cartilage in osteoarthritis
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Mitochondrial respiratory activity is altered in osteoarthritic human articular chondrocytes
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Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs
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Large‐scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis
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Hypoxia‐inducible factor 1α is involved in the prostaglandin metabolism of osteoarthritic cartilage through up‐regulation of microsomal prostaglandin E synthase 1 in articular chondrocytes
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Mitochondrial dysfunction activates cyclooxygenase 2 expression in cultured normal human chondrocytes
inferredcites →https://doi.org/10.1002/art.30333openalex-snapshot
Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α
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Interleukin‐6 plays an essential role in hypoxia‐inducible factor 2α–induced experimental osteoarthritic cartilage destruction in mice
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Microarray analysis reveals age‐related differences in gene expression during the development of osteoarthritis in mice
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Mitochondrial dysfunction increases inflammatory responsiveness to cytokines in normal human chondrocytes
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Hypoxia Promotes the Production and Inhibits the Destruction of Human Articular Cartilage
inferredcites →https://doi.org/10.1002/art.38399openalex-snapshot
Palmitate Has Proapoptotic and Proinflammatory Effects on Articular Cartilage and Synergizes With Interleukin‐1
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Mitochondrial Biogenesis Is Impaired in Osteoarthritis Chondrocytes but Reversible via Peroxisome Proliferator–Activated Receptor γ Coactivator 1α
inferredcites →https://doi.org/10.1002/art.39337openalex-snapshot
Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage
inferredcites →https://doi.org/10.1002/art.39618openalex-snapshot
Aging Promotes Sirtuin 3–Dependent Cartilage Superoxide Dismutase 2 Acetylation and Osteoarthritis
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Control of matrix synthesis in isolated bovine chondrocytes by extracellular and intracellular pH
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Mesenchymal stem cells in regenerative medicine: Opportunities and challenges for articular cartilage and intervertebral disc tissue engineering
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Effects of AURKA‐mediated degradation of SOD2 on mitochondrial dysfunction and cartilage homeostasis in osteoarthritis
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Quercetin attenuates oxidative stress‐induced apoptosis via SIRT1/AMPK‐mediated inhibition of ER stress in rat chondrocytes and prevents the progression of osteoarthritis in a rat model
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Effects of hypoxia on glucose transport in primary equine chondrocytes in vitro and evidence of reduced GLUT1 gene expression in pathologic cartilage in vivo
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High‐resolution magic angle spinning NMR spectroscopy of human osteoarthritic cartilage
inferredcites →https://doi.org/10.1007/s00011-016-0946-xopenalex-snapshot
The role of resolvin D1 in the regulation of inflammatory and catabolic mediators in osteoarthritis
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Chemically modified curcumin (CMC2.24) alleviates osteoarthritis progression by restoring cartilage homeostasis and inhibiting chondrocyte apoptosis via the NF-κB/HIF-2α axis
inferredcites →https://doi.org/10.1007/s00296-012-2373-9openalex-snapshot
l-Carnitine enhances extracellular matrix synthesis in human primary chondrocytes
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Arginine metabolism and nutrition in growth, health and disease
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Homoarginine, arginine, and relatives: analysis, metabolism, transport, physiology, and pathology
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Alterations of amino acid metabolism in osteoarthritis: its implications for nutrition and health
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Physiological dynamic compression regulates central energy metabolism in primary human chondrocytes
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Mitochondrial function, mitochondrial DNA and ageing: a reappraisal
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Metabolomic analysis of human synovial fluid and plasma reveals that phosphatidylcholine metabolism is associated with both osteoarthritis and diabetes mellitus
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Advanced glycation endproducts and osteoarthritis
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Application of Metabolomics to Osteoarthritis: from Basic Science to the Clinical Approach
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Citric Acid Cycle and Role of its Intermediates in Metabolism
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PI3K/Akt and caspase pathways mediate oxidative stress-induced chondrocyte apoptosis
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mTOR: A Potential Therapeutic Target in Osteoarthritis?
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The serial cultivation of human diploid cell strains
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Enzymatic activity and distribution of phospholipase A2 in human cartilage
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Candidate mediators of chondrocyte mechanotransduction via targeted and untargeted metabolomic measurements
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A review on phospholipids and their main applications in drug delivery systems
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Cartilage regeneration and ageing: Targeting cellular plasticity in osteoarthritis
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The contributions of respiration and glycolysis to extracellular acid production
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Changes in acetyl-CoA mediate Sik3-induced maturation of chondrocytes in endochondral bone formation
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Zinc protects chondrocytes from monosodium iodoacetate-induced damage by enhancing ATP and mitophagy
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Lipid mediators of inflammation in rheumatoid arthritis and osteoarthritis
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Inhibition of PI3K/AKT/mTOR signaling pathway promotes autophagy of articular chondrocytes and attenuates inflammatory response in rats with osteoarthritis
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Inflammatory mediators in osteoarthritis: A critical review of the state-of-the-art, current prospects, and future challenges
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High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue
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Expression of the GLUT1 and GLUT9 facilitative glucose transporters in embryonic chondroblasts and mature chondrocytes in ovine articular cartilage
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The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
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mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation
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Four Key Steps Control Glycolytic Flux in Mammalian Cells
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From Ancient Pathways to Aging Cells—Connecting Metabolism and Cellular Senescence
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Advances in Hypoxia-Inducible Factor Biology
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Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism
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Pro-inflammatory cytokines: The link between obesity and osteoarthritis
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Silk fibroin nanoparticles for celecoxib and curcumin delivery: ROS-scavenging and anti-inflammatory activities in an in vitro model of osteoarthritis
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ROS-induced ROS release in plant and animal cells
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Reactive oxygen species, aging and articular cartilage homeostasis
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Redox control of chondrocyte differentiation and chondrogenesis
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Pyruvate kinase M2: A simple molecule with complex functions
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Advanced oxidation protein products induce catabolic effect through oxidant-dependent activation of NF-κ B pathway in human chondrocyte
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Protectin DX attenuates IL-1β-induced inflammation via the AMPK/NF-κB pathway in chondrocytes and ameliorates osteoarthritis progression in a rat model
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Mechanotransduction in primary human osteoarthritic chondrocytes is mediated by metabolism of energy, lipids, and amino acids
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Fatty acids and osteoarthritis: different types, different effects
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Cardiovascular profile in osteoarthritis: a meta-analysis of cardiovascular events and risk factors
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Hypoxia inducible factor-1 alpha expression in human normal and osteoarthritic chondrocytes
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Diminished mitochondrial DNA integrity and repair capacity in OA chondrocytes
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Relative efficacies of omega-3 polyunsaturated fatty acids in reducing expression of key proteins in a model system for studying osteoarthritis
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Glutamate signaling in chondrocytes and the potential involvement of NMDA receptors in cell proliferation and inflammatory gene expression
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Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix
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Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes
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The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review
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Characterization of nitrotyrosine as a biomarker for arthritis and joint injury
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Palmitate has proapoptotic and proinflammatory effects on articular cartilage and synergizes with interleukin-1.
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Loss of Vhl in cartilage accelerated the progression of age-associated and surgically induced murine osteoarthritis
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Current evidence on risk factors for knee osteoarthritis in older adults: a systematic review and meta-analysis
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Excitatory amino acid glutamate: role in peripheral nociceptive transduction and inflammation in experimental and clinical osteoarthritis
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Metabolomic analysis of human plasma reveals that arginine is depleted in knee osteoarthritis patients
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Association of urinary metabolites with radiographic progression of knee osteoarthritis in overweight and obese adults: an exploratory study
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Hyperlipidaemia and incident osteoarthritis of the hand: a population-based case-control study
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Targeted lipidomics reveals activation of resolution pathways in knee osteoarthritis in humans
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Altered N-methyl D-aspartate receptor subunit expression causes changes to the circadian clock and cell phenotype in osteoarthritic chondrocytes
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Activation of AMPK-SIRT3 signaling is chondroprotective by preserving mitochondrial DNA integrity and function
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The association of plasma fatty acids levels with hand and knee osteoarthritis
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Differences in the composition of hip and knee synovial fluid in osteoarthritis: a nuclear magnetic resonance (NMR) spectroscopy study of metabolic profiles
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The association of plasma fatty acids with hand and knee osteoarthritis: the NEO study
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Osteoarthritis-associated basic calcium phosphate crystals alter immune cell metabolism and promote M1 macrophage polarization
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Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis
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Mitochondrial dysfunction in osteoarthritis
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mtDNA haplogroups and osteoarthritis in different geographic populations
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Epidemiology of Osteoarthritis
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Bioenergetics and the formation of mitochondrial reactive oxygen species
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Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release of a Lipid Attraction Signal
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Joint Physiology, Cartilage Metabolism, and the Etiology of Osteoarthritis
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Glucose-sensing mechanisms in eukaryotic cells
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Osteoarthritis and nitric oxide
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Invited review: the mitochondrion in osteoarthritis
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Ex Vivo Equine Cartilage Explant Osteoarthritis Model: A Metabolomics and Proteomics Study
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Aging, articular cartilage chondrocyte senescence and osteoarthritis
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Hypoxia-inducible factor-2α regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction
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Metabolic reprogramming in macrophages and dendritic cells in innate immunity
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Regulation of glucose metabolism from a liver-centric perspective
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Crosstalk between FLS and chondrocytes is regulated by HIF-2α-mediated cytokines in arthritis
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Role of cholesterol and lipid organization in disease
inferredcites →https://doi.org/10.1038/nature08780openalex-snapshot
Circulating mitochondrial DAMPs cause inflammatory responses to injury
inferredcites →https://doi.org/10.1038/nature11862openalex-snapshot
Metabolism of inflammation limited by AMPK and pseudo-starvation
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Pro-resolving lipid mediators are leads for resolution physiology
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Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development
inferredcites →https://doi.org/10.1038/nm.2153openalex-snapshot
Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction
inferredcites →https://doi.org/10.1038/nm.4324openalex-snapshot
Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment
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A guide to immunometabolism for immunologists
inferredcites →https://doi.org/10.1038/nri3859openalex-snapshot
Eicosanoid storm in infection and inflammation
inferredcites →https://doi.org/10.1038/nrrheum.2010.196openalex-snapshot
Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
inferredcites →https://doi.org/10.1038/nrrheum.2010.213openalex-snapshot
The role of mitochondria in osteoarthritis
inferredcites →https://doi.org/10.1038/nrrheum.2014.44openalex-snapshot
The individual and socioeconomic impact of osteoarthritis
inferredcites →https://doi.org/10.1038/nrrheum.2016.65openalex-snapshot
Ageing and the pathogenesis of osteoarthritis
inferredcites →https://doi.org/10.1038/nrrheum.2017.50openalex-snapshot
The role of metabolism in the pathogenesis of osteoarthritis
inferredcites →https://doi.org/10.1038/s41416-019-0620-5openalex-snapshot
New aspects of amino acid metabolism in cancer
inferredcites →https://doi.org/10.1038/s41419-020-2680-0openalex-snapshot
Stabilization of HIF-1α alleviates osteoarthritis via enhancing mitophagy
inferredcites →https://doi.org/10.1038/s41467-019-09839-xopenalex-snapshot
A small molecule promotes cartilage extracellular matrix generation and inhibits osteoarthritis development
inferredcites →https://doi.org/10.1038/s41467-019-13668-3openalex-snapshot
Mitochondrial TCA cycle metabolites control physiology and disease
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LDHA-mediated ROS generation in chondrocytes is a potential therapeutic target for osteoarthritis
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Mechanisms and regulation of cholesterol homeostasis
inferredcites →https://doi.org/10.1038/s41584-018-0001-0openalex-snapshot
Mitochondrial DNA variation and the pathogenesis of osteoarthritis phenotypes
inferredcites →https://doi.org/10.1038/s41586-019-0874-3openalex-snapshot
HIF-1α metabolically controls collagen synthesis and modification in chondrocytes
inferredcites →https://doi.org/10.1038/s41586-019-0920-1openalex-snapshot
The CH25H–CYP7B1–RORα axis of cholesterol metabolism regulates osteoarthritis
inferredcites →https://doi.org/10.1038/s41598-017-10158-8openalex-snapshot
The cross-sectional and longitudinal effect of hyperlipidemia on knee osteoarthritis: Results from the Dongfeng-Tongji cohort in China
inferredcites →https://doi.org/10.1038/s41598-018-34718-8openalex-snapshot
Hydrostatic pressure-generated reactive oxygen species induce osteoarthritic conditions in cartilage pellet cultures
inferredcites →https://doi.org/10.1038/s41598-018-34830-9openalex-snapshot
Intra-articular administration of IκBα kinase inhibitor suppresses mouse knee osteoarthritis via downregulation of the NF-κB/HIF-2α axis
inferredcites →https://doi.org/10.1038/s41598-019-46185-wopenalex-snapshot
Activation of The Phosphatidylcholine to Lysophosphatidylcholine Pathway Is Associated with Osteoarthritis Knee Cartilage Volume Loss Over Time
inferredcites →https://doi.org/10.1038/s41598-019-55297-2openalex-snapshot
Oral administration of N-acetyl cysteine prevents osteoarthritis development and progression in a rat model
inferredcites →https://doi.org/10.1038/s41598-020-62463-4openalex-snapshot
Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling
inferredcites →https://doi.org/10.1038/srep11722openalex-snapshot
Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration
inferredcites →https://doi.org/10.1038/srep13092openalex-snapshot
Stearic acid induces proinflammatory cytokine production partly through activation of lactate-HIF1α pathway in chondrocytes
inferredcites →https://doi.org/10.1038/srep43245openalex-snapshot
AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice
inferredcites →https://doi.org/10.1042/bj3210095openalex-snapshot
Evidence for a negative Pasteur effect in articular cartilage
inferredcites →https://doi.org/10.1053/joca.2002.0858openalex-snapshot
Molecular characterization and partial cDNA cloning of facilitative glucose transporters expressed in human articular chondrocytes; stimulation of 2-deoxyglucose uptake by IGF-I and elevated MMP-2 secretion by glucose deprivation
inferredcites →https://doi.org/10.1074/jbc.r110.118356openalex-snapshot
Triacylglycerol Homeostasis: Insights from Yeast
inferredcites →https://doi.org/10.1074/mcp.m800292-mcp200openalex-snapshot
Mitochondrial Dysregulation of Osteoarthritic Human Articular Chondrocytes Analyzed by Proteomics
inferredcites →https://doi.org/10.1084/jem.20150900openalex-snapshot
The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease
inferredcites →https://doi.org/10.1089/dna.2017.4048openalex-snapshot
Pyruvate Kinase M2 Modulates the Glycolysis of Chondrocyte and Extracellular Matrix in Osteoarthritis
inferredcites →https://doi.org/10.1089/jir.2019.0139openalex-snapshot
Magnolol Alleviates IL-1β-Induced Dysfunction of Chondrocytes Through Repression of SIRT1/AMPK/PGC-1α Signaling Pathway
inferredcites →https://doi.org/10.1093/ajcn/30.12.2083openalex-snapshot
Urea biosynthesis I. The urea cycle and relationships to the citric acid cycle
inferredcites →https://doi.org/10.1093/hmg/ddr540openalex-snapshot
C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes
inferredcites →https://doi.org/10.1093/rheumatology/keq380openalex-snapshot
Advanced glycation end products induce the expression of interleukin-6 and interleukin-8 by receptor for advanced glycation end product-mediated activation of mitogen-activated protein kinases and nuclear factor- B in human osteoarthritis chondrocytes
inferredcites →https://doi.org/10.1093/rheumatology/keu141openalex-snapshot
Malalignment: a possible target for prevention of incident knee osteoarthritis in overweight and obese women
inferredcites →https://doi.org/10.1093/rheumatology/kew207openalex-snapshot
Lysophosphatidylcholines to phosphatidylcholines ratio predicts advanced knee osteoarthritis
inferredcites →https://doi.org/10.1097/ajp.0000000000000517openalex-snapshot
Omega-6:Omega-3 PUFA Ratio, Pain, Functioning, and Distress in Adults With Knee Pain
inferredcites →https://doi.org/10.1097/bor.0000000000000353openalex-snapshot
Role of low-grade inflammation in osteoarthritis
inferredcites →https://doi.org/10.1097/bor.0000000000000373openalex-snapshot
Metabolic syndrome-associated osteoarthritis
inferredcites →https://doi.org/10.1097/bor.0000000000000463openalex-snapshot
Bioactive lipids in osteoarthritis: risk or benefit?
inferredcites →https://doi.org/10.1097/bor.0b013e3283494005openalex-snapshot
Aging and osteoarthritis
inferredcites →https://doi.org/10.1097/bor.0b013e328349c2b1openalex-snapshot
Inflammation in osteoarthritis
inferredcites →https://doi.org/10.1097/mol.0b013e328328d0a4openalex-snapshot
PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
inferredcites →https://doi.org/10.1098/rstb.1975.0050openalex-snapshot
Measurement of pH and ionic composition of pericellular sites
inferredcites →https://doi.org/10.1111/1440-1681.12537openalex-snapshot
PFKFB 3 modulates glycolytic metabolism and alleviates endoplasmic reticulum stress in human osteoarthritis cartilage
inferredcites →https://doi.org/10.1111/1756-185x.13061openalex-snapshot
Cholesterol metabolism in pathogenesis of osteoarthritis disease
inferredcites →https://doi.org/10.1111/1756-185x.13453openalex-snapshot
Association of Asian mitochondrial DNA haplogroup B with new development of knee osteoarthritis in Koreans
inferredcites →https://doi.org/10.1111/acel.12538openalex-snapshot
Function of the SIRT 3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease
inferredcites →https://doi.org/10.1111/fcp.12094openalex-snapshot
Advanced glycation end products‐induced chondrocyte apoptosis through mitochondrial dysfunction in cultured rabbit chondrocyte
inferredcites →https://doi.org/10.1111/j.1582-4934.2008.00474.xopenalex-snapshot
Remodelling of human osteoarthritic cartilage by FGF‐2, alone or combined with Sox9 via rAAV gene transfer
inferredcites →https://doi.org/10.1111/j.2042-7158.2012.01458.xopenalex-snapshot
Osteoarthritis of the knee and hip. Part I: aetiology and pathogenesis as a basis for pharmacotherapy
inferredcites →https://doi.org/10.1126/science.1160809openalex-snapshot
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
inferredcites →https://doi.org/10.1126/science.123.3191.309openalex-snapshot
On the Origin of Cancer Cells
inferredcites →https://doi.org/10.1136/annrheumdis-2011-200557openalex-snapshot
Autophagy activation by rapamycin reduces severity of experimental osteoarthritis
inferredcites →https://doi.org/10.1136/annrheumdis-2013-203231openalex-snapshot
Enhancement of the synthesis of n-3 PUFAs in fat-1 transgenic mice inhibits mTORC1 signalling and delays surgically induced osteoarthritis in comparison with wild-type mice
showing the first 200 of 257 · page through all 257
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/adfm.202418951openalex-snapshot
Advanced Injectable Microgels: Porous, Small‐Sized, and Lubricated Systems for Targeted Synergistic Therapy in Osteoarthritis
inferred← citeshttps://doi.org/10.1002/adfm.202420344openalex-snapshot
Self‐Lubricating and Self‐Healing Polyurethane Elastomer as a Meniscal Prosthesis to Delay Osteoarthritis Progression
inferred← citeshttps://doi.org/10.1002/adfm.78715openalex-snapshot
A Nano‐Cocoon Platform Attenuates Osteoarthritis Progression via Chem‐Bio Coupled ROS Scavenging and Cartilage Lubrication Restoration
inferred← citeshttps://doi.org/10.1002/adhm.202301953openalex-snapshot
Injectable Bioactive Antioxidative One‐Component Polycitrate Hydrogel with Anti‐Inflammatory Effects for Osteoarthritis Alleviation and Cartilage Protection
inferred← citeshttps://doi.org/10.1002/adhm.202302181openalex-snapshot
Articular Cartilage Regeneration via Induced Chondrocyte Autophagy by Sustained Release of Leptin Inhibitor from Thermo‐Sensitive Hydrogel through STAT3/REDD1/mTORC1 Cascade
inferred← citeshttps://doi.org/10.1002/adma.202212114openalex-snapshot
Cartilage Lacuna‐Inspired Microcarriers Drive Hyaline Neocartilage Regeneration
inferred← citeshttps://doi.org/10.1002/advs.202205859openalex-snapshot
Trimanganese Tetroxide Nanozyme protects Cartilage against Degeneration by Reducing Oxidative Stress in Osteoarthritis
inferred← citeshttps://doi.org/10.1002/advs.202302586openalex-snapshot
Effective Treatment of Knee Osteoarthritis Using a Nano‐Enabled Drug Acupuncture Technology in Mice
inferred← citeshttps://doi.org/10.1002/advs.202306722openalex-snapshot
Osmolarity‐Induced Altered Intracellular Molecular Crowding Drives Osteoarthritis Pathology
inferred← citeshttps://doi.org/10.1002/advs.202410414openalex-snapshot
ABCA6 Regulates Chondrogenesis and Inhibits Joint Degeneration via Orchestrated Cholesterol Efflux and Cellular Senescence
inferred← citeshttps://doi.org/10.1002/advs.202412379openalex-snapshot
M6A Demethyltransferase FTO Attenuates Meniscus Degeneration and Osteoarthritis via Orchestrating Autophagy and Energetic Metabolism
inferred← citeshttps://doi.org/10.1002/advs.202416149openalex-snapshot
Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration
inferred← citeshttps://doi.org/10.1002/advs.202504965openalex-snapshot
Dual‐Modular Hydrogel Microparticles with Precision‐Modulation of Inflammatory Microenvironment Dictate Full‐Thickness Cartilage Regeneration for Osteoarthritis Repair
inferred← citeshttps://doi.org/10.1002/advs.77905openalex-snapshot
Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism
inferred← citeshttps://doi.org/10.1002/ame2.70057openalex-snapshot
Long noncoding RNA GCH1 mediates mitophagy via the PTEN ‐induced kinase 1/Parkin pathway to drive chondrocyte dysfunction and cartilage degeneration in osteoarthritis
inferred← citeshttps://doi.org/10.1002/anbr.202400029openalex-snapshot
Biomimetic Nanomaterials for Osteoarthritis Treatment: Targeting Cartilage, Subchondral Bone, and Synovium
inferred← citeshttps://doi.org/10.1002/bit.28915openalex-snapshot
Recent Research on Chondrocyte Dedifferentiation and Insights for Regenerative Medicine
inferred← citeshttps://doi.org/10.1002/btm2.70116openalex-snapshot
Hypoxia‐preconditioned adipose‐derived stem cells with injectable small intestinal submucosa for enhanced cartilage repair in osteoarthritis
inferred← citeshttps://doi.org/10.1002/ccs3.12022openalex-snapshot
Adipocyte enhancer binding protein 1 knockdown alleviates osteoarthritis through inhibiting NF‐κB signaling pathway‐mediated inflammation and extracellular matrix degradation
inferred← citeshttps://doi.org/10.1002/ccs3.70008openalex-snapshot
Macrophages‐derived small extracellular vesicles regulate chondrocyte proliferation and affect osteoarthritis progression via upregulating Osteopontin expression
inferred← citeshttps://doi.org/10.1002/cph4.70052openalex-snapshot
SFRP 4 Regulates Chondrocyte Hypertrophy and Apoptosis via Wnt/Ca 2+ and Wnt/ JNK Pathways in Steroid‐Induced Osteonecrosis of the Femoral Head
inferred← citeshttps://doi.org/10.1002/cpz1.596openalex-snapshot
Animal Models of Osteoarthritis Part 1–Preclinical Small Animal Models: Challenges and Opportunities for Drug Development
inferred← citeshttps://doi.org/10.1002/exp.20220132openalex-snapshot
The potential role of synovial cells in the progression and treatment of osteoarthritis
inferred← citeshttps://doi.org/10.1002/exp.20250125openalex-snapshot
Artificial Chlorella Biohybrids for Alleviation of Cartilage Degeneration in Osteoarthritis
inferred← citeshttps://doi.org/10.1002/exp2.70185openalex-snapshot
Smart Nanodelivery Systems for Immunometabolic Modulation in Osteoarthritis
inferred← citeshttps://doi.org/10.1002/iid3.70423openalex-snapshot
LncRNA Mirt2 Attenuates Osteoarthritis Progression by Promoting miR‐429/TBK1‐Mediated Autophagy
inferred← citeshttps://doi.org/10.1002/jcp.70100openalex-snapshot
Bidirectional Regulatory Mechanisms of Disulfidptosis Govern Precision Targeting in Degenerative Bone Diseases and Osteosarcoma
inferred← citeshttps://doi.org/10.1002/jmri.28857openalex-snapshot
T2 Mapping of Patellar Cartilage After a Single First‐Time Episode of Traumatic Lateral Patellar Dislocation
inferred← citeshttps://doi.org/10.1002/jor.25420openalex-snapshot
Eugenol protects chondrocytes and articular cartilage by downregulating the JAK3/STAT4 signaling pathway
inferred← citeshttps://doi.org/10.1002/jor.70184openalex-snapshot
Cigarette Smoke Extract Alters the Inflammatory Secretome of Osteoarthritis‐Affected Synovium Increasing Joint Tissue Oxidative Stress in an Indirect Co‐Culture Model
inferred← citeshttps://doi.org/10.1002/jor.70279openalex-snapshot
Single‐Cell Analysis of Cartilage‐Derived Cells Identifies Diverse Populations and a Cholesterol/ER‐Stress Chondrocyte Subset in Knee OA
inferred← citeshttps://doi.org/10.1002/kjm2.70162openalex-snapshot
USP7 Regulates TRPV1 Deubiquitination to Mediate Chondrocyte Ferroptosis and Alleviate Osteoarthritis
inferred← citeshttps://doi.org/10.1002/kjm2.70280openalex-snapshot
IGF2BP3 Overexpression Accelerates Osteoarthritis Progression by Promoting Glycolysis via m 6 A ‐Dependent Stabilization of ECM1 mRNA
inferred← citeshttps://doi.org/10.1002/mco2.70519openalex-snapshot
Musculoskeletal Diseases: Mechanisms and Therapeutic Advances
inferred← citeshttps://doi.org/10.1002/ptr.70270openalex-snapshot
Astragalus membranaceus Polysaccharides Attenuate Osteoarthritis in Human Primary Chondrocytes and in Animal Model: Mechanism Study Using RNA ‐Seq and Network Pharmacology
inferred← citeshttps://doi.org/10.1002/ptr.7935openalex-snapshot
Natural anti‐inflammatory products for osteoarthritis: From molecular mechanism to drug delivery systems and clinical trials
inferred← citeshttps://doi.org/10.1002/ptr.7953openalex-snapshot
Ginkgolide K delays the progression of osteoarthritis by regulating YAP to promote the formation of cartilage extracellular matrix
inferred← citeshttps://doi.org/10.1002/smll.202302506openalex-snapshot
Small Joint Organoids 3D Bioprinting: Construction Strategy and Application
inferred← citeshttps://doi.org/10.1002/smsc.202500440openalex-snapshot
Chondrocyte‐Targeted Nanoparticles Loaded with N ‐Acetylcysteine Protect Articular Cartilage and Attenuate Osteoarthritis by Inhibiting Ferroptosis via Glutathione Maintenance
inferred← citeshttps://doi.org/10.1002/tox.24310openalex-snapshot
RETRACTED: PUM2 promoted osteoarthritis progression through PTEN ‐mediated chondrocyte ferroptosis by facilitating NEDD4 mRNA degradation
inferred← citeshttps://doi.org/10.1007/5584_2022_717openalex-snapshot
Articular Cartilage Regeneration in Veterinary Medicine
inferred← citeshttps://doi.org/10.1007/978-1-0716-2839-3_11openalex-snapshot
Metabolomic Profiling to Understand Chondrocyte Metabolism
inferred← citeshttps://doi.org/10.1007/978-3-031-25588-5_1openalex-snapshot
Aggrecan and Hyaluronan: The Infamous Cartilage Polyelectrolytes – Then and Now
inferred← citeshttps://doi.org/10.1007/s00011-025-01998-6openalex-snapshot
SIRT6 inhibits endoplasmic reticulum stress-mediated ferroptosis by activating Nrf2/HO-1 signaling to alleviate osteoarthritis
inferred← citeshttps://doi.org/10.1007/s00018-021-03983-8openalex-snapshot
Pharmaceutical therapeutics for articular regeneration and restoration: state-of-the-art technology for screening small molecular drugs
inferred← citeshttps://doi.org/10.1007/s00018-025-06073-1openalex-snapshot
The role of lactate on arthritis-associated cells: physiology, pathology, and therapeutic strategies
inferred← citeshttps://doi.org/10.1007/s00109-024-02473-1openalex-snapshot
New insights into the mechanisms and therapeutic strategies of chondrocyte autophagy in osteoarthritis
inferred← citeshttps://doi.org/10.1007/s00210-024-03179-4openalex-snapshot
Sappanone a alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis via activating the SIRT1/Nrf2 signaling pathway
inferred← citeshttps://doi.org/10.1007/s00210-024-03776-3openalex-snapshot
Senkyunolide I prevent chondrocytes from oxidative stress through Nrf2/HO-1 signaling pathway
inferred← citeshttps://doi.org/10.1007/s00223-024-01242-zopenalex-snapshot
Suppression of YAP Ameliorates Cartilage Degeneration in Ankle Osteoarthritis via Modulation of the Wnt/β-Catenin Signaling Pathway
inferred← citeshttps://doi.org/10.1007/s00335-025-10112-4openalex-snapshot
Unraveling the brain-joint axis: genetic, transcriptomic, and cohort insights from neuroticism to osteoarthritis
inferred← citeshttps://doi.org/10.1007/s00438-026-02417-zopenalex-snapshot
Targeting WWP1 ameliorates osteoarthritis by suppressing KLF15 ubiquitination to restore mtDNA and mitochondrial function
inferred← citeshttps://doi.org/10.1007/s00441-022-03639-4openalex-snapshot
Chondrocyte death involvement in osteoarthritis
inferred← citeshttps://doi.org/10.1007/s00774-024-01574-8openalex-snapshot
Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis
inferred← citeshttps://doi.org/10.1007/s10067-023-06742-1openalex-snapshot
Role of lipid metabolism gene KLF4 in osteoarthritis
inferred← citeshttps://doi.org/10.1007/s10409-024-23656-xopenalex-snapshot
Low-intensity laser alleviates cartilage degradation in a rat model of knee osteoarthritis by improving the biomechanics of joint muscles and cartilage
inferred← citeshttps://doi.org/10.1007/s10439-024-03667-xopenalex-snapshot
Metabolic Profiles of Encapsulated Chondrocytes Exposed to Short-Term Simulated Microgravity
inferred← citeshttps://doi.org/10.1007/s10439-025-03755-6openalex-snapshot
Chondrocytes Embedded in Agarose Generate Distinct Metabolic Heat Profiles Based on Media Carbon Sources
inferred← citeshttps://doi.org/10.1007/s10439-025-03792-1openalex-snapshot
Metabolic Heat Output of Chondrocytes: Implications for Joint Degeneration in Osteoarthritis
inferred← citeshttps://doi.org/10.1007/s10439-026-04170-1openalex-snapshot
Microcavitary Alginate Hydrogel Reverses Chondrocyte Dedifferentiation via Temporal Modulation of the p53 Pathway
inferred← citeshttps://doi.org/10.1007/s10528-023-10486-7openalex-snapshot
Mitochondria-Related Gene MAOB is a Key Biomarker of Osteoarthritis and Inhibition of Its Expression Reduces LPS-induced Chondrocyte Damage
inferred← citeshttps://doi.org/10.1007/s10616-024-00695-2openalex-snapshot
Suppressive effect of curcumin on apoptosis of articular chondrocytes via regulation on NF-κB pathway and NLRP3 inflammasome
inferred← citeshttps://doi.org/10.1007/s10719-024-10176-5openalex-snapshot
SUMOylated GLUT1 inhibited the glycometabolism disorder in chondroctyes during osteoarthritis
inferred← citeshttps://doi.org/10.1007/s10735-023-10163-4openalex-snapshot
Intra-articular delivery of geraniol encapsulated by pH/redox-responsive nanogel ameliorates osteoarthritis by regulating oxidative stress and inflammation
inferred← citeshttps://doi.org/10.1007/s10735-026-10977-yopenalex-snapshot
Extracellular matrix assembly during chondrogenic differentiation of amniotic fluid- and adipose-derived mesenchymal stromal cells under TGF-β3 induction
inferred← citeshttps://doi.org/10.1007/s10787-021-00814-xopenalex-snapshot
Exogenous stromal cell-derived factor-1 (SDF-1) suppresses the NLRP3 inflammasome and inhibits pyroptosis in synoviocytes from osteoarthritic joints via activation of the AMPK signaling pathway
inferred← citeshttps://doi.org/10.1007/s10787-025-01665-6openalex-snapshot
Mechanism of action and new developments in the study of curcumin in the treatment of osteoarthritis: a narrative review
inferred← citeshttps://doi.org/10.1007/s10787-026-02390-4openalex-snapshot
Curcumin as a natural therapeutic agent for osteoarthritis: molecular mechanisms, preclinical evidence, clinical applications, and future perspectives
inferred← citeshttps://doi.org/10.1007/s11010-023-04818-9openalex-snapshot
The role and intervention of mitochondrial metabolism in osteoarthritis
inferred← citeshttps://doi.org/10.1007/s11033-022-07467-1openalex-snapshot
Upregulation of P2Y12 inhibits chondrocyte apoptosis in lumbar osteoarthritis through the PI3K/AKT signaling pathway
inferred← citeshttps://doi.org/10.1007/s11033-024-09426-4openalex-snapshot
Short-term regulation of TSFM level does not alter amyloidogenesis and mitochondrial function in type-specific cells
inferred← citeshttps://doi.org/10.1007/s11033-024-09499-1openalex-snapshot
Toll-like receptor activation regulates the paracrine effect of adipose-derived mesenchymal stem cells on reversing osteoarthritic phenotype of chondrocytes
inferred← citeshttps://doi.org/10.1007/s11033-025-11141-7openalex-snapshot
Lycium barbarum polysaccharide alleviates osteoarthritis progression in mice DMM model by inhibiting chondrocytes ferroptosis and promoting the gut Lactobacillus/Alistipes ratio
inferred← citeshttps://doi.org/10.1007/s11356-021-17780-0openalex-snapshot
Balneotherapy year in review 2021: focus on the mechanisms of action of balneotherapy in rheumatic diseases
inferred← citeshttps://doi.org/10.1007/s11357-023-01001-2openalex-snapshot
Identified senescence endotypes in aged cartilage are reflected in the blood metabolome
inferred← citeshttps://doi.org/10.1007/s11596-022-2627-zopenalex-snapshot
GW842166X Alleviates Osteoarthritis by Repressing LPS-mediated Chondrocyte Catabolism in Mice
inferred← citeshttps://doi.org/10.1007/s11596-026-00166-zopenalex-snapshot
Lactate and Acidification: Emerging Metabolic Regulators of Osteoarthritis
inferred← citeshttps://doi.org/10.1007/s11626-025-01090-7openalex-snapshot
lncRNA PVT1 regulates chondrocyte proliferation and apoptosis through the glycolysis process mediated by miR-552-3p/PKM2 to promote osteoarthritis
inferred← citeshttps://doi.org/10.1007/s11926-021-01042-6openalex-snapshot
A White Paper on Collagen Hydrolyzates and Ultrahydrolyzates: Potential Supplements to Support Joint Health in Osteoarthritis?
inferred← citeshttps://doi.org/10.1007/s12011-023-03801-1openalex-snapshot
Circulating Copper Is Associated with Inflammatory Biomarkers in Greek Older Adults with Osteoarthritis
inferred← citeshttps://doi.org/10.1007/s12013-024-01415-5openalex-snapshot
CDK5 Upregulated by ELF3 Transcription Promotes IL-1β-induced Inflammation and Extracellular Matrix Degradation in Human Chondrocytes
inferred← citeshttps://doi.org/10.1007/s12013-025-01862-8openalex-snapshot
Integrated LC-MS/MS, Network Pharmacology, and Experimental Validation Reveal the Mechanism of Eucommia Ulmoides against Osteoarthritis
inferred← citeshttps://doi.org/10.1007/s12603-022-1739-2openalex-snapshot
A Cross-Sectional Study of Association between Plasma Selenium Levels and the Prevalence of Osteoarthritis: Data from the Xiangya Osteoarthritis Study
inferred← citeshttps://doi.org/10.1007/s13577-023-00926-2openalex-snapshot
Autophagy and apoptosis: regulatory factors of chondrocyte phenotype transition in osteoarthritis
inferred← citeshttps://doi.org/10.1007/s13679-023-00520-5openalex-snapshot
Obesity, Metabolic Syndrome, and Osteoarthritis—An Updated Review
inferred← citeshttps://doi.org/10.1007/s13679-026-00761-0openalex-snapshot
Obesity-Associated Osteoarthritis: Mechanical-Metabolic Pathogenesis, Obesity Memory and Dual-Target Therapy
inferred← citeshttps://doi.org/10.1007/s40520-024-02812-9openalex-snapshot
Causal factors for osteoarthritis risk revealed by mendelian randomization analysis
inferred← citeshttps://doi.org/10.1007/s43465-026-01885-0openalex-snapshot
Non-Surgical Therapies for Knee Osteoarthritis: Current Evidence and Emerging Strategies
inferred← citeshttps://doi.org/10.1016/b978-0-323-90597-8.00017-7openalex-snapshot
In vivo models of human articular cartilage mechanosensitivity
inferred← citeshttps://doi.org/10.1016/b978-0-443-45056-3.00010-8openalex-snapshot
Mesenchymal stem cells and extracellular vesicles in cartilage regeneration
inferred← citeshttps://doi.org/10.1016/j.aanat.2026.152799openalex-snapshot
Perspectives on intrinsic articular cartilage interfaces
inferred← citeshttps://doi.org/10.1016/j.actbio.2022.07.050openalex-snapshot
N-cadherin mimetic hydrogel enhances MSC chondrogenesis through cell metabolism
inferred← citeshttps://doi.org/10.1016/j.actbio.2023.07.024openalex-snapshot
Harnessing knee joint resident mesenchymal stem cells in cartilage tissue engineering
inferred← citeshttps://doi.org/10.1016/j.ajps.2023.100830openalex-snapshot
High drug loading hydrophobic cross-linked dextran microspheres as novel drug delivery systems for the treatment of osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.apsb.2022.09.020openalex-snapshot
Roles of focal adhesion proteins in skeleton and diseases
inferred← citeshttps://doi.org/10.1016/j.apsb.2024.06.009openalex-snapshot
Combination of anti-inflammatory therapy and RNA interference by light-inducible hybrid nanomedicine for osteoarthritis treatment
inferred← citeshttps://doi.org/10.1016/j.archoralbio.2025.106233openalex-snapshot
Single monoiodoacetic acid injection reveals toll-like receptor, oestrogen, oxidative stress, and altered energy metabolism as key drivers of temporomandibular joint osteoarthritis in female rats
inferred← citeshttps://doi.org/10.1016/j.arr.2022.101725openalex-snapshot
Deciphering clock genes as emerging targets against aging
inferred← citeshttps://doi.org/10.1016/j.arr.2023.101981openalex-snapshot
Prevention and treatment of inflammatory arthritis with traditional Chinese medicine: Underlying mechanisms based on cell and molecular targets
inferred← citeshttps://doi.org/10.1016/j.arr.2024.102275openalex-snapshot
Senolytic therapeutics: An emerging treatment modality for osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.arr.2024.102294openalex-snapshot
Lipids and lipid metabolism in cellular senescence: Emerging targets for age-related diseases
inferred← citeshttps://doi.org/10.1016/j.arr.2025.102802openalex-snapshot
Molecular hydrogen therapy: A “democratic” emerging strategy against aging and age-related diseases
inferred← citeshttps://doi.org/10.1016/j.arr.2026.103131openalex-snapshot
Mitochondria-associated endoplasmic reticulum membranes as aging-sensitive signaling hubs in degenerative musculoskeletal diseases
inferred← citeshttps://doi.org/10.1016/j.arr.2026.103139openalex-snapshot
Age-associated regulation of chondrocyte hypertrophy in osteoarthritis: Mechanisms, therapeutic implications, and cartilage fate reprogramming
inferred← citeshttps://doi.org/10.1016/j.arres.2025.100130openalex-snapshot
Global hotspots and prospective trends for chondrocyte metabolic changes and oxidative stress in osteoarthritis: A bibliometric analysis
inferred← citeshttps://doi.org/10.1016/j.arthro.2023.08.019openalex-snapshot
Tranexamic Acid Causes Chondral Injury Through Chondrocytes Apoptosis Induced by Activating Endoplasmic Reticulum Stress
inferred← citeshttps://doi.org/10.1016/j.bbadis.2024.167090openalex-snapshot
Oleic and linoleic acids promote chondrocyte apoptosis by inhibiting autophagy via downregulation of SIRT1/FOXO1 signaling
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2024.119788openalex-snapshot
TGF-β2 enhances glycolysis in chondrocytes via TβRI/p-Smad3 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.bbrc.2024.149885openalex-snapshot
Disease-modifying potential of diphenyl diselenide in an experimental osteoarthritis model
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152497openalex-snapshot
Tryptophan metabolic dysregulation drives immune activation and cartilage degradation in osteoarthritis: Functional validation integrated with transcriptomic and single-cell RNA sequencing
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152917openalex-snapshot
Diverse mechanisms of KLFs in skeletal diseases and their clinical potentials
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152958openalex-snapshot
HMGCR-driven cholesterol metabolism dysregulation and its role in osteoarthritis diagnosis and immune regulation
inferred← citeshttps://doi.org/10.1016/j.bcp.2022.115343openalex-snapshot
Exosome modification to better alleviates endoplasmic reticulum stress induced chondrocyte apoptosis and osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.bcp.2023.115542openalex-snapshot
PD184352 exerts anti-inflammatory and antioxidant effects by promoting activation of the Nrf2/HO-1 axis
inferred← citeshttps://doi.org/10.1016/j.bcp.2023.115930openalex-snapshot
Epigenetic modification and exosome effects on autophagy in osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116420openalex-snapshot
Selective STAT3 inhibitor STX-0119 alleviates osteoarthritis progression by modulating the STAT3/PPARγ signaling pathway
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2022.10.012openalex-snapshot
Breakthrough of extracellular vesicles in pathogenesis, diagnosis and treatment of osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2024.09.021openalex-snapshot
An intra articular injectable Mitocelle recovers dysfunctional mitochondria in cellular organelle disorders
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2025.07.043openalex-snapshot
Bioenergetic-active hydrogel drives extracellular matrix synthesis for cartilage repair
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2026.01.031openalex-snapshot
Nanozyme hydrogels remodel pathological microenvironment for temporomandibular joint osteoarthritis therapy via inhibiting MAPK signal pathway
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2026.06.015openalex-snapshot
Restoring cartilage-subchondral bone metabolism with biphasic magnesium microspheres ameliorate early osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2026.06.023openalex-snapshot
Mechanical loading primes MSC-derived exosomes to promote cartilage repair
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2026.06.045openalex-snapshot
Bioinspired 0D mitochondrial bioenergetic actuators rewire cartilage progenitor cell metabolism for osteoarthritis remission
inferred← citeshttps://doi.org/10.1016/j.bioadv.2026.215053openalex-snapshot
Sustained modulation of the inflammatory microenvironment for cartilage repair using an ROS-responsive hydrogel delivering CircSERPINE2-loaded exosomes
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2024.122845openalex-snapshot
Sustained therapeutic effects of self-assembled hyaluronic acid nanoparticles loaded with α-Ketoglutarate in various osteoarthritis stages
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2025.123283openalex-snapshot
Gel@CAT-L hydrogel mediates mitochondrial unfolded protein response to regulate reactive oxygen species and mitochondrial homeostasis in osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.bioorg.2022.105939openalex-snapshot
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.114118openalex-snapshot
Exercise induced meteorin-like protects chondrocytes against inflammation and pyroptosis in osteoarthritis by inhibiting PI3K/Akt/NF-κB and NLRP3/caspase-1/GSDMD signaling
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115751openalex-snapshot
Combination of curcumin and catalase protects against chondrocyte injury and knee osteoarthritis progression by suppressing oxidative stress
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115772openalex-snapshot
Sarsasapogenin inhibits YAP1-dependent chondrocyte ferroptosis to alleviate osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116194openalex-snapshot
Sakuranetin reduces inflammation and chondrocyte dysfunction in osteoarthritis by inhibiting the PI3K/AKT/NF-κB pathway
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118897openalex-snapshot
Doxycycline and IGF-1 as a synergistic combination therapy for OA disease modification
inferred← citeshttps://doi.org/10.1016/j.bone.2021.116299openalex-snapshot
Glucocorticoid caused lactic acid accumulation and damage in human chondrocytes via ROS-mediated inhibition of Monocarboxylate Transporter 4
inferred← citeshttps://doi.org/10.1016/j.bone.2024.117132openalex-snapshot
PGC-1α/LDHA signaling facilitates glycolysis initiation to regulate mechanically induced bone remodeling under inflammatory microenvironment
inferred← citeshttps://doi.org/10.1016/j.bone.2024.117313openalex-snapshot
Carbonic anhydrase 2 is important for articular chondrocyte function and metabolic homeostasis
inferred← citeshttps://doi.org/10.1016/j.bonr.2022.101620openalex-snapshot
Amino acid metabolism in skeletal cells
inferred← citeshttps://doi.org/10.1016/j.carbpol.2026.125081openalex-snapshot
Injectable gelatin/hyaluronic acid hydrogels incorporating oxidized alginate microparticles for controlled delivery of platelet-derived factors in cartilage regeneration
inferred← citeshttps://doi.org/10.1016/j.cclet.2022.108079openalex-snapshot
Thermosensitive injectable hydrogel loaded with hypoxia-induced exosomes maintains chondrocyte phenotype through NDRG3-mediated hypoxic response
inferred← citeshttps://doi.org/10.1016/j.cej.2023.146479openalex-snapshot
Coenzyme a-responsive hydrogel sensor for wireless monitoring and treatment of osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.cej.2024.151443openalex-snapshot
Activatable theranostic nanoprobes for Fluorescence/MR imaging and microenvironment remodeling of early cartilage degeneration
inferred← citeshttps://doi.org/10.1016/j.cej.2024.152049openalex-snapshot
3D-bioprinted anti-senescence organoid scaffolds repair cartilage defect and prevent joint degeneration via miR-23b/ELOVL5-mediated metabolic rewiring
inferred← citeshttps://doi.org/10.1016/j.cej.2024.154797openalex-snapshot
Gradient scaffolds for osteochondral tissue engineering and regeneration
inferred← citeshttps://doi.org/10.1016/j.cej.2024.155189openalex-snapshot
A tetrahedral framework nucleic acids-based gene therapeutic nanococktail alleviates cartilage damage and protects against osteoarthritis progression
inferred← citeshttps://doi.org/10.1016/j.cej.2024.158451openalex-snapshot
Injectable biomimetic microcarriers harness synergistic effects of paracrine factors and cellular membranes to alleviate osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.cej.2026.173711openalex-snapshot
Chondrocyte-targeting hydrogel loaded with puerarin limits osteoarthritis development by maintaining mitochondrial function
inferred← citeshttps://doi.org/10.1016/j.celbio.2025.100220openalex-snapshot
Local sustained H2 release assisted stem cell transplantation for enhanced osteoarthritic cartilage regeneration
inferred← citeshttps://doi.org/10.1016/j.cellsig.2025.112063openalex-snapshot
SIRT3 mitigates osteoarthritis by suppressing ferroptosis through activating AMPK signaling pathway
inferred← citeshttps://doi.org/10.1016/j.cellsig.2026.112482openalex-snapshot
Targeting BMP2 signaling pathway in osteogenesis and osteoarthritis: A path toward safer regenerative therapies
inferred← citeshttps://doi.org/10.1016/j.cellsig.2026.112545openalex-snapshot
Reactivating mitochondrial quality control via the Nrf2 pathway to combat metabolic stress in diabetic osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.cjnm.2025.100011openalex-snapshot
Mechanism and research progress of improving cartilage injury based on the combination of active ingredients in traditional Chinese medicine and biomaterials
inferred← citeshttps://doi.org/10.1016/j.clinsp.2023.100254openalex-snapshot
MicroRNA-15a/β1,4-GalT-I axis contributes to cartilage degeneration via NF-κB signaling in osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.clinsp.2024.100378openalex-snapshot
Association between hepatic steatosis and fibrosis and arthritis among US adults: A population-based study
inferred← citeshttps://doi.org/10.1016/j.clnesp.2026.103253openalex-snapshot
Collagen protein supplementation does not modulate biomarkers of bone metabolism following total hip arthroplasty: a randomized, double-blind, placebo-controlled trial
inferred← citeshttps://doi.org/10.1016/j.cmpb.2025.108902openalex-snapshot
Predicting the Heterogeneous Chemo-Mechano-Biological Degeneration of Cartilage Using 3-D Biphasic Finite Elements
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2024.114243openalex-snapshot
Supramolecular nanoparticle loaded with bilirubin enhances cartilage protection and alleviates osteoarthritis via modulating oxidative stress and inflammatory responses
inferred← citeshttps://doi.org/10.1016/j.compositesb.2022.110437openalex-snapshot
Modeling dECM-based inflammatory cartilage microtissues in vitro for drug screening
inferred← citeshttps://doi.org/10.1016/j.compositesb.2023.110709openalex-snapshot
Synergistic strategy constructed novel double-network scaffolds with active micro-environment pH stabilization and M2-macrophage polarization for cartilage defect repair
inferred← citeshttps://doi.org/10.1016/j.compositesb.2024.111974openalex-snapshot
Engineered dECM-based microsystem promotes cartilage regeneration in osteoarthritis by synergistically enhancing chondrogenesis of BMSCs and anti-inflammatory effect
inferred← citeshttps://doi.org/10.1016/j.crfs.2024.100687openalex-snapshot
Unraveling the role of serum metabolites in the relationship between plant-based diets and bone health in community-dwelling older adults
inferred← citeshttps://doi.org/10.1016/j.cyto.2023.156377openalex-snapshot
Gene signature based on glycolysis is closely related to immune infiltration of patients with osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.cyto.2025.157016openalex-snapshot
The role of CXCL10 in cartilage development and diseases
inferred← citeshttps://doi.org/10.1016/j.ebiom.2021.103300openalex-snapshot
MiR-214-3p, a novel possible therapeutic target for the pathogenesis of osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2025.119453openalex-snapshot
Environmental pollutants as emerging risk factors in osteoarthritis: Mechanistic and epidemiological evidence
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2026.120027openalex-snapshot
Glycolytic metabolic reprogramming and mitochondrial dysfunction: A novel mechanism underlying PAEs-promoted cartilage inflammatory phenotype
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116773openalex-snapshot
Design, synthesis and structure-activity relationship of novel 2-pyrimidinylindole derivatives as orally available anti-obesity agents
inferred← citeshttps://doi.org/10.1016/j.engreg.2023.12.002openalex-snapshot
Microenvironment-responsive nanosystems for osteoarthritis therapy
inferred← citeshttps://doi.org/10.1016/j.exger.2024.112611openalex-snapshot
Association between sarcopenic obesity and osteoarthritis: The potential mediating role of insulin resistance
inferred← citeshttps://doi.org/10.1016/j.fbio.2021.101220openalex-snapshot
Different n-6/n-3 PUFA diets with fish oil attenuated osteoarthritis in ovariectomized mice via targeting the NLRP3 inflammasome
inferred← citeshttps://doi.org/10.1016/j.gendis.2024.101247openalex-snapshot
Development of novel osteoarthritis therapy by targeting AMPK-β-catenin-Runx2 signaling
inferred← citeshttps://doi.org/10.1016/j.gendis.2025.102002openalex-snapshot
Purinergic signaling in osteoarthritis: Mechanistic insights into pathogenesis and therapeutic targeting
inferred← citeshttps://doi.org/10.1016/j.gene.2022.147063openalex-snapshot
Identification of chondrocyte subpopulations in osteoarthritis using single-cell sequencing analysis
inferred← citeshttps://doi.org/10.1016/j.gene.2024.148740openalex-snapshot
UBE2I regulates the nuclear translocation of hnRNPA2B1 by contributing to SUMO modification in osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.heliyon.2022.e12039openalex-snapshot
Potential metabolites of Arecaceae family for the natural anti-osteoarthritis medicine: A review
inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e19975openalex-snapshot
Identification of EGFR as an essential regulator in chondrocytes ferroptosis of osteoarthritis using bioinformatics, in vivo, and in vitro study
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e34064openalex-snapshot
Effects of resveratrol on biochemical and structural outcomes in osteoarthritis: A systematic review and meta-analysis of preclinical studies
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e36905openalex-snapshot
Overactivation of NF-kB pathway can induce apoptosis by down-regulating glycolysis in human degenerative nucleus pulposus cells
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.129862openalex-snapshot
Microenvironment-responsive bilayer hydrogel microspheres with gelatin-shell for osteoarthritis treatment
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.133840openalex-snapshot
Intra-articular injection of modified citrus pectin and hyaluronate gel induces synergistic effects in treating osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.143610openalex-snapshot
The preparation of silk fibroin-based hydrogels and their applications in cartilage repair
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2026.152986openalex-snapshot
BioEnerGel: A mechanically-resilient bioenergetic hydrogel enhances chondrogenic differentiation for cartilage regeneration
inferred← citeshttps://doi.org/10.1016/j.imbio.2025.153122openalex-snapshot
sgp130Fc alleviates cartilage degeneration and knee osteoarthritis by inhibiting IL-6 trans-signaling pathway
inferred← citeshttps://doi.org/10.1016/j.injury.2026.113730openalex-snapshot
MicroRNAs regulate viability, longevity and extracellular matrix secretions of mesenchymal stem cell-derived chondrocytes in vitro
inferred← citeshttps://doi.org/10.1016/j.intimp.2022.109225openalex-snapshot
Salinomycin alleviates osteoarthritis progression via inhibiting Wnt/β-catenin signaling
inferred← citeshttps://doi.org/10.1016/j.intimp.2022.109489openalex-snapshot
Methyl gallate prevents oxidative stress induced apoptosis and ECM degradation in chondrocytes via restoring Sirt3 mediated autophagy and ameliorates osteoarthritis progression
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110506openalex-snapshot
Senescence-responsive miR-33-5p promotes chondrocyte senescence and osteoarthritis progression by targeting SIRT6
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.111109openalex-snapshot
Identification of anterior cruciate ligament fibroblasts and their contribution to knee osteoarthritis progression using single-cell analyses
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.111755openalex-snapshot
SIRT3 alleviates high glucose-induced chondrocyte injury through the promotion of autophagy and suppression of apoptosis in osteoarthritis progression
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112619openalex-snapshot
Deferoxamine alleviates chondrocyte senescence and osteoarthritis progression by maintaining iron homeostasis
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112688openalex-snapshot
Targeting G6PD to mitigate cartilage inflammation in TMJOA: The NOX4-ROS-MAPK axis as a therapeutic avenue
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113071openalex-snapshot
Lactate-upregulated ARG2 expression induces cellular senescence in fibroblast-like synoviocytes of osteoarthritis via activating the mTOR/S6K1 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113417openalex-snapshot
LncRNA NKILA attenuates the progression of osteoarthritis through the targeted inhibition of the NF-κB pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113589openalex-snapshot
Isoliensinine suppresses chondrocytes pyroptosis against osteoarthritis via the MAPK/NF-κB signaling pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113954openalex-snapshot
Mitochondria-rich extracellular vesicles derived from the culture supernatant of human synovial Fluid‐derived mesenchymal stem cells Inhibited senescence of Stressed/inflammatory Licensed chondrocytes and Delayed Osteoarthritis progression
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.114323openalex-snapshot
Notopterol mitigates osteoarthritis progression and relieves pain in mice by inhibiting PI3K/Akt/GPX4-mediated ferroptosis
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.114841openalex-snapshot
Chondrocyte-targeted α-Solanine through HIF-1α regulating glycolysis to reduce the ferroptosis of chondrocyte in osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.115729openalex-snapshot
CircP4HA3/miR-5001-5p/THBS2 axis promotes chondrocyte senescence and cartilage degradation during osteoarthritis progression
inferred← citeshttps://doi.org/10.1016/j.intimp.2026.116352openalex-snapshot
Bee sting acupuncture mitigates osteoarthritis in male mice via PPAR-γ activation: integrated network pharmacology, transcriptomics, and experimental validation
inferred← citeshttps://doi.org/10.1016/j.intimp.2026.116742openalex-snapshot
Daidzein alleviates knee osteoarthritis via activation of the EGFR/Raf-1/ERK1/2 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.isci.2023.107491openalex-snapshot
Low-oxygen tension augments chondrocyte sensitivity to biomimetic thermomechanical cues in cartilage-engineered constructs
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