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Pinocembrin induces ER stress mediated apoptosis and suppresses autophagy in melanoma cells
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/mc.20272openalex-snapshot
Pinocembrin triggers Bax‐dependent mitochondrial apoptosis in colon cancer cells
inferredcites →https://doi.org/10.1002/path.2584openalex-snapshot
Tumour suppression by p53: the importance of apoptosis and cellular senescence
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Regulation of Apoptosis in Melanoma Cells: Critical Targets for Therapeutic Strategies
inferredcites →https://doi.org/10.1007/s00253-005-0116-5openalex-snapshot
Combinatorial biosynthesis of flavones and flavonols in Escherichia coli
inferredcites →https://doi.org/10.1007/s10495-016-1217-6openalex-snapshot
Caspase-12 is involved in stretch-induced apoptosis mediated endoplasmic reticulum stress
inferredcites →https://doi.org/10.1007/s12035-015-9125-2openalex-snapshot
The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications
inferredcites →https://doi.org/10.1016/j.bbamcr.2013.06.028openalex-snapshot
ER stress-induced cell death mechanisms
inferredcites →https://doi.org/10.1016/j.bbrc.2005.02.163openalex-snapshot
Suppression of PI3K/mTOR pathway rescues LLC cells from cell death induced by hypoxia
inferredcites →https://doi.org/10.1016/j.bpj.2011.06.018openalex-snapshot
Protein Folding Inside the Cell
inferredcites →https://doi.org/10.1016/j.canlet.2008.07.005openalex-snapshot
Endoplasmic reticulum stress and autophagy as targets for cancer therapy
inferredcites →https://doi.org/10.1016/j.canlet.2015.08.030openalex-snapshot
Honokiol induces autophagy of neuroblastoma cells through activating the PI3K/Akt/mTOR and endoplasmic reticular stress/ERK1/2 signaling pathways and suppressing cell migration
inferredcites →https://doi.org/10.1016/j.cell.2011.10.026openalex-snapshot
Autophagy: Renovation of Cells and Tissues
inferredcites →https://doi.org/10.1016/j.ejca.2005.03.034openalex-snapshot
Meta-analysis of risk factors for cutaneous melanoma: III. Family history, actinic damage and phenotypic factors
inferredcites →https://doi.org/10.1016/j.jep.2010.10.032openalex-snapshot
Propolis: Is there a potential for the development of new drugs?
inferredcites →https://doi.org/10.1016/j.jiac.2017.02.009openalex-snapshot
Pinocembrin enriched fraction of Elytranthe parasitica (L.) Danser induces apoptosis in HCT 116 colorectal cancer cells
inferredcites →https://doi.org/10.1016/j.molcel.2009.08.021openalex-snapshot
Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome
inferredcites →https://doi.org/10.1016/j.tcb.2013.06.005openalex-snapshot
IRE1: ER stress sensor and cell fate executor
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Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
inferredcites →https://doi.org/10.1023/a:1016119328968openalex-snapshot
Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: An update
inferredcites →https://doi.org/10.1038/cdd.2010.191openalex-snapshot
The Beclin 1 network regulates autophagy and apoptosis
inferredcites →https://doi.org/10.1038/cdd.2017.155openalex-snapshot
A role for caspase-8 and TRAIL-R2/DR5 in ER-stress-induced apoptosis
inferredcites →https://doi.org/10.1038/nature05661openalex-snapshot
Melanoma biology and new targeted therapy
inferredcites →https://doi.org/10.1038/ncb1547openalex-snapshot
Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40
inferredcites →https://doi.org/10.1038/nm1608openalex-snapshot
Molecular imaging of Akt kinase activity
inferredcites →https://doi.org/10.1038/nrc2663openalex-snapshot
Apoptosis and cancer: the genesis of a research field
inferredcites →https://doi.org/10.1038/nrm2199openalex-snapshot
Signal integration in the endoplasmic reticulum unfolded protein response
inferredcites →https://doi.org/10.1038/sj.cdd.4401373openalex-snapshot
Roles of CHOP/GADD153 in endoplasmic reticulum stress
inferredcites →https://doi.org/10.1038/sj.cdd.4402200openalex-snapshot
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium
inferredcites →https://doi.org/10.1038/sj.embor.7400779openalex-snapshot
Mediators of endoplasmic reticulum stress‐induced apoptosis
inferredcites →https://doi.org/10.1038/sj.onc.1207197openalex-snapshot
Phosphoinositide 3-kinase accelerates autophagic cell death during glucose deprivation in the rat cardiomyocyte-derived cell line H9c2
inferredcites →https://doi.org/10.1056/nejmoa1604958openalex-snapshot
Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
inferredcites →https://doi.org/10.1074/jbc.c700195200openalex-snapshot
The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy
inferredcites →https://doi.org/10.1074/jbc.m112.339127openalex-snapshot
Autophagy Is a Protective Mechanism for Human Melanoma Cells under Acidic Stress
inferredcites →https://doi.org/10.1074/jbc.m406933200openalex-snapshot
CHOP Is Involved in Endoplasmic Reticulum Stress-induced Apoptosis by Enhancing DR5 Expression in Human Carcinoma Cells
inferredcites →https://doi.org/10.1074/jbc.m607007200openalex-snapshot
Endoplasmic Reticulum Stress Triggers Autophagy
inferredcites →https://doi.org/10.1080/10286020802240418openalex-snapshot
Synthesis and enantiomeric resolution of (±)-pinocembrin
inferredcites →https://doi.org/10.1080/15548627.2015.1091141openalex-snapshot
ER stress: Autophagy induction, inhibition and selection
inferredcites →https://doi.org/10.1080/15548627.2016.1246107openalex-snapshot
New anti-cancer molecules targeting HSPA5/BIP to induce endoplasmic reticulum stress, autophagy and apoptosis
inferredcites →https://doi.org/10.1098/rsfs.2013.0012openalex-snapshot
Modelling the effect of GRP78 on anti-oestrogen sensitivity and resistance in breast cancer
inferredcites →https://doi.org/10.1111/j.1365-2133.2007.07855.xopenalex-snapshot
Apoptosis pathways as promising targets for skin cancer therapy
inferredcites →https://doi.org/10.1111/j.1600-0560.2009.01359.xopenalex-snapshot
Autophagy in cutaneous malignant melanoma
inferredcites →https://doi.org/10.1126/science.1146361openalex-snapshot
IRE1 Signaling Affects Cell Fate During the Unfolded Protein Response
inferredcites →https://doi.org/10.1126/science.1254312openalex-snapshot
Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis
inferredcites →https://doi.org/10.1128/mcb.01453-06openalex-snapshot
Autophagy Is Activated for Cell Survival after Endoplasmic ReticulumStress
inferredcites →https://doi.org/10.1128/mcb.16.8.4273openalex-snapshot
Signals from the Stressed Endoplasmic Reticulum Induce C/EBP-Homologous Protein (CHOP/GADD153)
inferredcites →https://doi.org/10.1152/physrev.00001.2011openalex-snapshot
The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α
inferredcites →https://doi.org/10.1155/2010/930509openalex-snapshot
Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy
inferredcites →https://doi.org/10.1155/2013/379850openalex-snapshot
Pinocembrin: A Novel Natural Compound with Versatile Pharmacological and Biological Activities
inferredcites →https://doi.org/10.1158/0008-5472.can-04-1454openalex-snapshot
Ultraviolet B but not Ultraviolet A Radiation Initiates Melanoma
inferredcites →https://doi.org/10.1158/0008-5472.can-07-0325openalex-snapshot
GRP78 Induction in Cancer: Therapeutic and Prognostic Implications
inferredcites →https://doi.org/10.1172/jci73939openalex-snapshot
mTOR: a pharmacologic target for autophagy regulation
inferredcites →https://doi.org/10.1186/1478-811x-8-31openalex-snapshot
PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration
inferredcites →https://doi.org/10.1186/2045-3701-4-41openalex-snapshot
Pinocembrin suppresses TGF-β1-induced epithelial-mesenchymal transition and metastasis of human Y-79 retinoblastoma cells through inactivating αvβ3 integrin/FAK/p38α signaling pathway
inferredcites →https://doi.org/10.1196/annals.1299.032openalex-snapshot
Caspase‐12 and ER‐Stress‐Mediated Apoptosis
inferredcites →https://doi.org/10.1371/journal.pbio.0040423openalex-snapshot
Autophagy Counterbalances Endoplasmic Reticulum Expansion during the Unfolded Protein Response
inferredcites →https://doi.org/10.18632/oncotarget.21750openalex-snapshot
Celastrol induces apoptosis in hepatocellular carcinoma cells via targeting ER-stress/UPR
inferredcites →https://doi.org/10.3329/bjp.v8i3.14795openalex-snapshot
Antiproliferative and apoptotic effects of pinocembrin in human prostate cancer cells
inferredcites →https://doi.org/10.3389/fonc.2017.00078openalex-snapshot
Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell Fate
inferredcites →https://doi.org/10.3390/ijms16047027openalex-snapshot
Antiangiogenesis, Loss of Cell Adhesion and Apoptosis Are Involved in the Antitumoral Activity of Proteases from V. cundinamarcensis (C. candamarcensis) in Murine Melanoma B16F1
inferredcites →https://doi.org/10.4161/auto.1.2.1738openalex-snapshot
Does Autophagy Contribute To Cell Death?
inferredcites →https://doi.org/10.4161/auto.1.3.2017openalex-snapshot
Autophagy and Aging: The Importance of Maintaining "Clean" Cells
inferredcites →https://doi.org/10.4161/auto.7.10.16818openalex-snapshot
Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis
inferredcites →https://doi.org/10.4161/auto.9099openalex-snapshot
Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Biomechanically reduced expression of Derlin-3 is linked to the apoptosis of chondrocytes in the mandibular condylar cartilage via the endoplasmic reticulum stress pathway
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FeCl3⋅6H2O-mediated cyclization of fluorinated 2’-hydroxychalcones in alcohol medium into flavanones with antiviral activity
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Iridium(III)-BBIP complexes induce apoptosis via PI3K/AKT/mTOR pathway and inhibit A549 lung tumor growth in vivo
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Pinocembrin inhibits melanoma progression via Ets1-mediated Smad3 transcription to enhance anti-PD-1 therapy
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Pectolinarigenin inhibits cell viability, migration and invasion and induces apoptosis via a ROS‑mitochondrial apoptotic pathway in melanoma cells
inferred← citeshttps://doi.org/10.5493/wjem.v15.i4.110482openalex-snapshot
Pinocembrin as a novel anti-cancer agent: Exploring preclinical evidence along with therapeutic potential
inferred← citeshttps://doi.org/10.56845/rebs.v3i1.30openalex-snapshot
Valorization of the residual bagasse of Mexican oregano (Lippia graveolens HBK) by obtaining fractions enriched in pinocembrin
inferred← citeshttps://doi.org/10.56845/terys.v1i1.169openalex-snapshot
Valorización del bagazo residual de orégano mexicano (Lippia graveolens HBK) mediante la obtención de fracciones enriquecidas en pinocembrina
inferred← citeshttps://doi.org/10.6084/m9.figshare.13226305openalex-snapshot
Additional file 1 of Pinocembrin ameliorates intermittent hypoxia-induced neuroinflammation through BNIP3-dependent mitophagy in a murine model of sleep apnea
inferred← citeshttps://doi.org/10.6084/m9.figshare.26964773openalex-snapshot
Additional file 1 of Evaluation of the cytotoxic activity of chemically characterized propolis originating from different geographic regions and vitamin D co-supplementation against human ovarian cancer cells
inferred← citeshttps://doi.org/10.7150/ijbs.32550openalex-snapshot
Melatonin Increases the Sensitivity of Hepatocellular Carcinoma to Sorafenib through the PERK-ATF4-Beclin1 Pathway
inferred← citeshttps://doi.org/10.7150/thno.36254openalex-snapshot
Repurposing Brigatinib for the Treatment of Colorectal Cancer Based on Inhibition of ER-phagy
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