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Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity

https://doi.org/10.1016/j.cmet.2023.02.013

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Linoleic Acid

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The combination of gut microbiota and metabolomics reveals the effects of polysaccharides from Schisandra chinensis on microbiota and metabolic profile in Alzheimer's disease rats

inferred← citeshttps://doi.org/10.1002/mco2.70405openalex-snapshot

cZFP609 Tethering BiP Alleviates Cartilage Degradation in Osteoarthritis via Remedying Aberrant ER‐Mitochondrial Contacts

inferred← citeshttps://doi.org/10.1002/mog2.70023openalex-snapshot

Unlocking T‐Cell Plasticity in the Tumor Microenvironment: Implications for Cancer Progression and Therapeutic Strategies

inferred← citeshttps://doi.org/10.1002/rcm.9968openalex-snapshot

Metabolomics Analysis Using Chromatography–Mass Spectrometry to Investigate the Mechanism of Cyclosporine in the Treatment of Aplastic Anemia

inferred← citeshttps://doi.org/10.1007/s00018-026-06081-9openalex-snapshot

Lactiplantibacillus plantarum GUANKE ameliorates influenza a virus-induced inflammation and lung barrier dysfunction through enhancing mitophagy and improving oxidative phosphorylation

inferred← citeshttps://doi.org/10.1007/s00109-026-02659-9openalex-snapshot

Exercise and CD8+ T cells: mechanisms of immune modulation in antitumor responses

inferred← citeshttps://doi.org/10.1007/s00203-025-04487-wopenalex-snapshot

Antimicrobial and antibiofilm microbial lipids: biological activity, experimental testing, therapeutic and recent application

inferred← citeshttps://doi.org/10.1007/s00203-025-04644-1openalex-snapshot

Research progress in plant endophyte-mediated lignocellulosic biomass degradation and valorization: a review

inferred← citeshttps://doi.org/10.1007/s00216-025-05785-4openalex-snapshot

Comprehensive MALDI mass spectrometry imaging of tumor regions post-neoadjuvant therapy

inferred← citeshttps://doi.org/10.1007/s00281-024-01011-yopenalex-snapshot

Harnessing the tumor microenvironment to boost adoptive T cell therapy with engineered lymphocytes for solid tumors

inferred← citeshttps://doi.org/10.1007/s10555-024-10211-9openalex-snapshot

The role of mitochondria in tumor metastasis and advances in mitochondria-targeted cancer therapy

inferred← citeshttps://doi.org/10.1007/s10555-025-10266-2openalex-snapshot

Metal-modulated T cell antitumor immunity and emerging metalloimmunotherapy

inferred← citeshttps://doi.org/10.1007/s10787-026-02300-8openalex-snapshot

Syagrus coronata fixed oil attenuates inflammation, oxidative stress and pulmonary alterations in L-arginine-induced pancreatitis

inferred← citeshttps://doi.org/10.1007/s11010-025-05462-1openalex-snapshot

Nutritional modulation of metabolic signaling within the tumor microenvironment for cancer therapy

inferred← citeshttps://doi.org/10.1007/s11684-025-1176-9openalex-snapshot

Metabolic biomarkers for predicting onset and severity of CAR-T therapy-induced cytokine release syndrome in multiple myeloma

inferred← citeshttps://doi.org/10.1007/s11912-025-01718-7openalex-snapshot

Host-related Determinants of Response to Immunotherapy in Non-small Cell Lung Cancer: The Interplay of Body Composition, Metabolism, Sex and Immune Regulation

inferred← citeshttps://doi.org/10.1007/s12010-026-05676-zopenalex-snapshot

Identification and Validation of the Breast Cancer Diagnostic Biomarker SVEP1 and Its Relationship With CD8 + T Cell Activation Using Bioinformatics and Machine Learning

inferred← citeshttps://doi.org/10.1007/s12032-025-03092-7openalex-snapshot

Essential oil from Tragopogon dubius selectively inhibits breast (MCF-7) and glioblastoma (LN-18) cancer cell proliferation; insights into antioxidant, genoprotective potential, and GCMS, GCGCTOFMS-based profiling

inferred← citeshttps://doi.org/10.1007/s12035-026-06124-zopenalex-snapshot

Melatonin Ameliorates Neuropathic Pain in Mice by Regulating Pyroptosis Through Gut Microbiota-Mediated Linoleic Acid

inferred← citeshttps://doi.org/10.1007/s12672-026-05185-9openalex-snapshot

Metabolomics assisted by transcriptomics analysis to reveal metabolic characteristics and potential biomarkers of early-onset colorectal cancer

inferred← citeshttps://doi.org/10.1007/s41207-025-00829-8openalex-snapshot

Nutritional profile of acorn flour from three Tunisian Quercus L. species: interspecific and intraspecific variation

inferred← citeshttps://doi.org/10.1007/s44466-025-00001-5openalex-snapshot

Phospholipid metabolism in innate immunity and inflammation: from basic to clinic

inferred← citeshttps://doi.org/10.1016/b978-0-12-824465-4.00275-1openalex-snapshot

Immunometabolism Governs T Cell Immunity

inferred← citeshttps://doi.org/10.1016/j.aimed.2026.100612openalex-snapshot

The regulatory effects of Yinchen Wuling powder on chronic Hepatitis B patients with NAs by integrating network pharmacology and metabolomics: A randomized -controlled clinical study

inferred← citeshttps://doi.org/10.1016/j.apsb.2024.07.021openalex-snapshot

Precise targeting of lipid metabolism in the era of immuno-oncology and the latest advances in nano-based drug delivery systems for cancer therapy

inferred← citeshttps://doi.org/10.1016/j.apsb.2025.03.017openalex-snapshot

Celastrol-loaded ginsenoside Rg3 liposomes boost immunotherapy by remodeling obesity-related immunosuppressive tumor microenvironment in melanoma

inferred← citeshttps://doi.org/10.1016/j.autrev.2024.103579openalex-snapshot

Metabolic heterogeneity in tumor microenvironment – A novel landmark for immunotherapy

inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115050openalex-snapshot

Jingfang granules ameliorate inflammation and immune disorders in mice exposed to low temperature and high humidity by restoring the dysregulation of gut microbiota and fecal metabolites

inferred← citeshttps://doi.org/10.1016/j.bjps.2025.12.005openalex-snapshot

Lipase A as a lipid metabolism-related biomarker and therapeutic target in hypertrophic scars

inferred← citeshttps://doi.org/10.1016/j.canlet.2023.216267openalex-snapshot

Lipid metabolism reprogramming of CD8+ T cell and therapeutic implications in cancer

inferred← citeshttps://doi.org/10.1016/j.canlet.2024.216641openalex-snapshot

A deep neural network predictor to predict the sensitivity of neoadjuvant chemoradiotherapy in locally advanced rectal cancer

inferred← citeshttps://doi.org/10.1016/j.canlet.2025.218219openalex-snapshot

HHLA2 promotes immune evasion in EGFR-mutant lung cancer by inhibiting CD8+ T cell glutamine metabolism via KIR3DL3 interaction

inferred← citeshttps://doi.org/10.1016/j.cbd.2025.101466openalex-snapshot

α-Ketoglutarate modulates the mechanisms of toxicity in crucian carp kidneys chronically exposed to NaHCO3: Metabolomics insights

inferred← citeshttps://doi.org/10.1016/j.ccell.2024.11.003openalex-snapshot

Mannose metabolism reshapes T cell differentiation to enhance anti-tumor immunity

inferred← citeshttps://doi.org/10.1016/j.cclet.2026.112477openalex-snapshot

Satellite-structured self-assembled nanoparticles of Herpetospermum caudigerum seeds to enhance its physical stability

inferred← citeshttps://doi.org/10.1016/j.cej.2024.153364openalex-snapshot

Organelle synergy unleashed: Modulating mitochondrial-endoplasmic reticulum contacts with a self-assembled prodrug amplifies ferroptosis for innovative cancer therapy

inferred← citeshttps://doi.org/10.1016/j.cej.2025.168843openalex-snapshot

In situ construction "Metabolism-Immunity" crosstalk rewiring bioreactor with single-dose mitochondria energizing hydrogel for amplifying T cell fitness and anti-tumor immunity

inferred← citeshttps://doi.org/10.1016/j.cell.2024.08.029openalex-snapshot

Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy

inferred← citeshttps://doi.org/10.1016/j.celrep.2024.114156openalex-snapshot

ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection

inferred← citeshttps://doi.org/10.1016/j.celrep.2025.115234openalex-snapshot

Emerging insights into the impact of systemic metabolic changes on tumor-immune interactions

inferred← citeshttps://doi.org/10.1016/j.celrep.2025.116623openalex-snapshot

Fatty acids modulate the colorectal cancer immune microenvironment via regulating the interaction and transactivation of PPARα/δ and P53

inferred← citeshttps://doi.org/10.1016/j.clnesp.2024.11.013openalex-snapshot

Metabolome-wide Mendelian randomization assessing the causal relationship between blood metabolites and primary ovarian insufficiency

inferred← citeshttps://doi.org/10.1016/j.cmet.2023.07.006openalex-snapshot

Emerging therapies in cancer metabolism

inferred← citeshttps://doi.org/10.1016/j.cmet.2024.01.012openalex-snapshot

Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5

inferred← citeshttps://doi.org/10.1016/j.cmet.2024.02.009openalex-snapshot

Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment

inferred← citeshttps://doi.org/10.1016/j.cmet.2025.03.003openalex-snapshot

Pyruvate kinase M2 activation reprograms mitochondria in CD8 T cells, enhancing effector functions and efficacy of anti-PD1 therapy

inferred← citeshttps://doi.org/10.1016/j.cmet.2025.12.012openalex-snapshot

Microbial metabolite FAD mobilizes adipocyte lipid remodeling to enhance cancer immunotherapy efficacy

inferred← citeshttps://doi.org/10.1016/j.coi.2024.102486openalex-snapshot

Eating for immunity: how diet shapes our defenses

inferred← citeshttps://doi.org/10.1016/j.compbiomed.2024.107926openalex-snapshot

Single-cell RNA-seq reveals the metabolic status of immune cells response to immunotherapy in triple-negative breast cancer

inferred← citeshttps://doi.org/10.1016/j.crfs.2024.100831openalex-snapshot

Changes in lipids and medium- and long-chain fatty acids during the spontaneous fermentation of ripened pu-erh tea

inferred← citeshttps://doi.org/10.1016/j.critrevonc.2025.104878openalex-snapshot

Fatty acid in the tumor microenvironment: Perspectives for immunotherapy

inferred← citeshttps://doi.org/10.1016/j.cytogfr.2026.01.004openalex-snapshot

GDF15 in the tumor microenvironment: A central mediator of cancer immunometabolism and therapeutic resistance

inferred← citeshttps://doi.org/10.1016/j.devcel.2026.02.020openalex-snapshot

Unleashing T cell surveillance for the eradication of quiescent persister tumor cells resistant to neoadjuvant chemotherapy

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2023.115723openalex-snapshot

Metabolomic responses based on transcriptome of the hepatopancreas in Exopalaemon carinicauda under carbonate alkalinity stress

inferred← citeshttps://doi.org/10.1016/j.fbio.2025.107870openalex-snapshot

Trash to treasure: Cowhide was completely hydrolyzed by Bacillus velezensis LZ676 to prepare bioactive mixture and metabonomics analysis

inferred← citeshttps://doi.org/10.1016/j.fertnstert.2023.11.025openalex-snapshot

CD24+ decidual stromal cells: a novel heterogeneous population with impaired regulatory T cell induction and potential association with recurrent miscarriage

inferred← citeshttps://doi.org/10.1016/j.foodres.2025.116895openalex-snapshot

Baijiu: Chemical compositions, biological functions, and endogenous metabolic profiles

inferred← citeshttps://doi.org/10.1016/j.gaost.2026.03.006openalex-snapshot

Compositional analysis and biosafety assessment of Cercis glabra seed oil

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.130706openalex-snapshot

The combination of Brassica rapa L. polysaccharides and cisplatin enhances the anti liver cancer effect and improves intestinal microbiota and metabolic disorders

inferred← citeshttps://doi.org/10.1016/j.imbio.2025.153099openalex-snapshot

Untargeted metabolomics reveals postoperative metabolic dynamics in hepatic cystic echinococcosis patients

inferred← citeshttps://doi.org/10.1016/j.immuni.2024.08.003openalex-snapshot

PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis

inferred← citeshttps://doi.org/10.1016/j.indcrop.2025.120853openalex-snapshot

Optimization and characterization of peach kernel oil extraction using supercritical fluid extraction

inferred← citeshttps://doi.org/10.1016/j.isci.2026.116445openalex-snapshot

Multiomics reveals fatty acid metabolism and immune remodeling in retinal artery occlusion

inferred← citeshttps://doi.org/10.1016/j.it.2025.07.014openalex-snapshot

Mitochondria and lysosomes in T cell immunometabolism

inferred← citeshttps://doi.org/10.1016/j.it.2025.08.005openalex-snapshot

Mitochondrial lipid metabolism in tumor immunosurveillance and evasion

inferred← citeshttps://doi.org/10.1016/j.it.2026.05.012openalex-snapshot

Mitochondrial Ca2+ signaling: A metabolic rheostat defining tumor and immune cell fate

inferred← citeshttps://doi.org/10.1016/j.jare.2024.11.021openalex-snapshot

Oncogenic cholesterol rewires lipid metabolism in hepatocellular carcinoma via the CSNK2A1-IGF2R Ser2484 axis

inferred← citeshttps://doi.org/10.1016/j.jare.2025.06.037openalex-snapshot

Perfluorooctane sulfonic acid impairs spermatogenesis via the liver-gut microbiota-testis axis: a central role of chenodeoxycholic acid metabolism

inferred← citeshttps://doi.org/10.1016/j.jconrel.2026.114776openalex-snapshot

An osteoimmunomodulatory microneedle patch targeting ER-mitochondria calcium crosstalk for periodontal tissue regeneration

inferred← citeshttps://doi.org/10.1016/j.jep.2024.119216openalex-snapshot

Beaveria bassiana (Balsamo) Vuillemin combined with cinnamaldehyde enhances anti-hepatocellular carcinoma effects of T cells by the PGC-1α/DRP1-regulated mitochondrial biogenesis and fission

inferred← citeshttps://doi.org/10.1016/j.jep.2025.120222openalex-snapshot

Nicotinic acid from Bubali Cornu alleviates H1N1-induced acute lung injury via dual antiviral and anti-inflammatory actions: A bioactivity-driven discovery

inferred← citeshttps://doi.org/10.1016/j.jep.2025.120623openalex-snapshot

The discovery of the material basis and mechanism of gypsum as an antipyretic based on the theory of the diverse applications of raw and processed products

inferred← citeshttps://doi.org/10.1016/j.jfutfo.2025.10.008openalex-snapshot

Comprehensive Review of Acer truncatum Seed Oil: Sustainable Extraction Technologies, Unique Bioactive Profile, and Emerging Applications

inferred← citeshttps://doi.org/10.1016/j.jpba.2024.116370openalex-snapshot

Revealing metabolic alterations in brucellosis patients by targeted metabolomics

inferred← citeshttps://doi.org/10.1016/j.jpba.2024.116624openalex-snapshot

Integrated network pharmacology, mass cytometry and multi-omics analysis the effect of Jingfang granule on intestinal immune disorder in mice with cold-dampness syndrome

inferred← citeshttps://doi.org/10.1016/j.jpha.2024.101150openalex-snapshot

Targeting tumor metabolism to augment CD8+ T cell anti-tumor immunity

inferred← citeshttps://doi.org/10.1016/j.jpha.2026.101582openalex-snapshot

Classification of pulmonary inflammation stages and assessment of multicomponent drug intervention based on spatiotemporal imaging variations utilizing RhB-conjugated poly-L-lysine nanoparticles

inferred← citeshttps://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108252openalex-snapshot

Exploring the genetic causal inference between plasma lipidome and hemorrhagic stroke

inferred← citeshttps://doi.org/10.1016/j.metabol.2025.156273openalex-snapshot

Fatty acid metabolism: The crossroads in intestinal homeostasis and tumor

inferred← citeshttps://doi.org/10.1016/j.microc.2025.116458openalex-snapshot

Comprehensive characterization of volatile and non-volatile compounds in the different parts of dandelion (Taraxacum mongolicum) integrating HS-GC-IMS, LC-MS and molecular networking

inferred← citeshttps://doi.org/10.1016/j.molmed.2025.08.005openalex-snapshot

Deciphering the MYCN-driven metabolic microenvironment of neuroblastoma

inferred← citeshttps://doi.org/10.1016/j.neuropharm.2026.110931openalex-snapshot

Ciprofloxacin exposure impairs neurogenesis and E/I balance in human cortical organoids

inferred← citeshttps://doi.org/10.1016/j.omtn.2024.102155openalex-snapshot

Metabolism pathway-based subtyping in endometrial cancer: An integrated study by multi-omics analysis and machine learning algorithms

inferred← citeshttps://doi.org/10.1016/j.omton.2025.200933openalex-snapshot

Metabolites and metabolic pathway reactions links to sensitization of immunotherapy in pan-cancer

inferred← citeshttps://doi.org/10.1016/j.pestbp.2025.106350openalex-snapshot

Insecticidal effect and mechanism of Metarhizium anisopliae ZHKUJGZ1 against Solenopsis invicta (Hymenoptera: Formicidae)

inferred← citeshttps://doi.org/10.1016/j.phymed.2025.157310openalex-snapshot

Alpha-linolenic acid reverses colorectal cancer drug resistance by suppressing secreted phosphoprotein 1 expression and tumor stemness

inferred← citeshttps://doi.org/10.1016/j.phymed.2025.157559openalex-snapshot

Shenling Baizhu Powder potentiates immunotherapy response: putative roles of gut microbial remodeling and fatty acid metabolism modulation

inferred← citeshttps://doi.org/10.1016/j.tem.2024.09.003openalex-snapshot

Targeting ACSLs to modulate ferroptosis and cancer immunity

inferred← citeshttps://doi.org/10.1016/j.tem.2024.11.014openalex-snapshot

Lipids guide T cell antitumor immunity by shaping their metabolic and functional fitness

inferred← citeshttps://doi.org/10.1016/j.tem.2025.08.009openalex-snapshot

CD8+ T cell stressors converge on shared metabolic–epigenetic networks

inferred← citeshttps://doi.org/10.1016/j.theriogenology.2024.09.020openalex-snapshot

Eicosatrienoic acid enhances the quality of in vitro matured porcine oocytes by reducing PRKN-mediated ubiquitination of CISD2

inferred← citeshttps://doi.org/10.1016/j.tifs.2025.105320openalex-snapshot

Buckwheat 2.0: From climate-resilient crop to personalized nutrition product– a model approach for future food industry

inferred← citeshttps://doi.org/10.1016/j.trecan.2023.06.003openalex-snapshot

Diet, nutrient supply, and tumor immune responses

inferred← citeshttps://doi.org/10.1016/j.trecan.2024.03.010openalex-snapshot

Immunometabolism of CD8+ T cell differentiation in cancer

inferred← citeshttps://doi.org/10.1016/j.trecan.2025.11.012openalex-snapshot

Lipids grease the chain of cancer progression

inferred← citeshttps://doi.org/10.1016/j.xcrm.2025.102310openalex-snapshot

An age-related decrease in leptin contributes to CD8+ T cell aging in the tumor microenvironment

inferred← citeshttps://doi.org/10.1016/j.ymben.2024.10.009openalex-snapshot

Applying metabolic control strategies to engineered T cell cancer therapies

inferred← citeshttps://doi.org/10.1016/j.ymthe.2025.02.031openalex-snapshot

Presetting CAR-T cells during ex vivo biomanufacturing

inferred← citeshttps://doi.org/10.1021/acs.est.5c16131openalex-snapshot

Multiomics Reveals the Mechanisms of Rhizosphere Symbiotic Fungi in Mitigating Micro(nano)plastics Transfer and Toxicity in Food Chains

inferred← citeshttps://doi.org/10.1021/acsinfecdis.5c00840openalex-snapshot

Trained Immunity Empowers Vaccine Design and Application

inferred← citeshttps://doi.org/10.1021/jacs.5c15220openalex-snapshot

Spatiotemporal Cascade Targeting from the Cell Membrane to the Endoplasmic Reticulum for Chemoimmunotherapy via the Cyclometalated Iridium-Fatty Acid Scaffold

inferred← citeshttps://doi.org/10.1038/s12276-026-01783-3openalex-snapshot

The interplay between lipid metabolism, cancer progression and anti-cancer immunity

inferred← citeshttps://doi.org/10.1038/s41389-026-00600-wopenalex-snapshot

Fatty acid uptake mediated by FABP4 promotes the formation of CD8+T cell senescence through lipid peroxidation in the adipocyte-rich microenvironment of Ovarian Cancer

inferred← citeshttps://doi.org/10.1038/s41392-024-01954-6openalex-snapshot

Metabolic regulation of the immune system in health and diseases: mechanisms and interventions

inferred← citeshttps://doi.org/10.1038/s41392-024-01979-xopenalex-snapshot

Cold and hot tumors: from molecular mechanisms to targeted therapy

inferred← citeshttps://doi.org/10.1038/s41392-025-02295-8openalex-snapshot

Oleic acid restores the impaired antitumor immunity of γδ-T cells induced by palmitic acid

inferred← citeshttps://doi.org/10.1038/s41392-025-02367-9openalex-snapshot

Transforming acidic coiled-coil-containing protein 3-mediated lipid metabolism reprogramming impairs CD8+ T-cell cytotoxicity in hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1038/s41392-026-02827-wopenalex-snapshot

Multifunctional-engineered NK cells overcome tumor immunosuppression by combining PD-L1 and HLA-E targeting and endogenous IL15 production

inferred← citeshttps://doi.org/10.1038/s41416-024-02762-zopenalex-snapshot

Metabolic adaptations in prostate cancer

inferred← citeshttps://doi.org/10.1038/s41418-024-01409-zopenalex-snapshot

Spermine synthase engages in macrophages M2 polarization to sabotage antitumor immunity in hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1038/s41418-026-01769-8openalex-snapshot

Mitochondrial calcium uptake drives organelle remodeling to promote inflammasome-dependent cytokine release

inferred← citeshttps://doi.org/10.1038/s41420-024-02240-8openalex-snapshot

PCK1 as a target for cancer therapy: from metabolic reprogramming to immune microenvironment remodeling

inferred← citeshttps://doi.org/10.1038/s41420-025-02351-wopenalex-snapshot

Reprogramming of fatty acid metabolism: a hidden force regulating the occurrence and progression of cholangiocarcinoma

inferred← citeshttps://doi.org/10.1038/s41420-025-02397-wopenalex-snapshot

New insights into T cell metabolism in liver cancer: from mechanism to therapy

inferred← citeshttps://doi.org/10.1038/s41420-025-02584-9openalex-snapshot

Tumor metabolome remolded by low dose mitochondrial uncoupler elicites robust CD8+ T cell response

inferred← citeshttps://doi.org/10.1038/s41423-024-01206-1openalex-snapshot

The influence of metabolic disorders on adaptive immunity

inferred← citeshttps://doi.org/10.1038/s41423-024-01224-zopenalex-snapshot

Regulation of CD8+ T cells by lipid metabolism in cancer progression

inferred← citeshttps://doi.org/10.1038/s41423-025-01260-3openalex-snapshot

GLP1 alleviates oleic acid-propelled lipocalin-2 generation by tumor-infiltrating CD8+ T cells to reduce polymorphonuclear MDSC recruitment and enhances viral immunotherapy in pancreatic cancer

inferred← citeshttps://doi.org/10.1038/s41423-026-01411-0openalex-snapshot

Lipid metabolism reprogramming shapes the immune landscape in the tumor microenvironment

inferred← citeshttps://doi.org/10.1038/s41467-024-46377-7openalex-snapshot

Mitochondrial metabolism sustains CD8+ T cell migration for an efficient infiltration into solid tumors

inferred← citeshttps://doi.org/10.1038/s41467-024-50138-xopenalex-snapshot

Inhibition of DUSP18 impairs cholesterol biosynthesis and promotes anti-tumor immunity in colorectal cancer

inferred← citeshttps://doi.org/10.1038/s41467-024-51500-9openalex-snapshot

LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness

inferred← citeshttps://doi.org/10.1038/s41467-025-58452-8openalex-snapshot

Investigative needle core biopsies support multimodal deep-data generation in glioblastoma

inferred← citeshttps://doi.org/10.1038/s41467-025-59562-zopenalex-snapshot

Dysregulated mast cell activation induced by diabetic milieu exacerbates the progression of diabetic peripheral neuropathy in mice

inferred← citeshttps://doi.org/10.1038/s41467-025-63146-2openalex-snapshot

Targeting spermine metabolism to overcome immunotherapy resistance in pancreatic cancer

inferred← citeshttps://doi.org/10.1038/s41467-026-74315-2openalex-snapshot

Targeting DGAT1 reprograms lipid landscape and restores CD8⁺ T cell immunity in pancreatic cancer

inferred← citeshttps://doi.org/10.1038/s41538-026-00791-xopenalex-snapshot

Metabolomic profiling of goji fermentation: enhancing functional metabolites with high-glucose-adaptive LAB

inferred← citeshttps://doi.org/10.1038/s41564-025-02140-2openalex-snapshot

Mycobacterium tuberculosis-derived linoleic acid increases regulatory T cell function to promote bacterial survival within macrophages

inferred← citeshttps://doi.org/10.1038/s41565-026-02235-9openalex-snapshot

Oral nano-delivery of a gut microbial metabolite enhances T cell stemness for cancer immunotherapy

inferred← citeshttps://doi.org/10.1038/s41573-024-01098-wopenalex-snapshot

Targeting metabolic dysfunction of CD8 T cells and natural killer cells in cancer

inferred← citeshttps://doi.org/10.1038/s41577-025-01221-xopenalex-snapshot

Regulators of CD8+ T cell exhaustion

inferred← citeshttps://doi.org/10.1038/s41577-025-01229-3openalex-snapshot

Microenvironmental regulation of solid tumour resistance to CAR T cell therapy

inferred← citeshttps://doi.org/10.1038/s41577-025-01258-yopenalex-snapshot

Metabolites as signalling molecules in the tumour immune microenvironment

inferred← citeshttps://doi.org/10.1038/s41577-026-01322-1openalex-snapshot

A guide to CAR T cell therapies: development, current status and future prospects

inferred← citeshttps://doi.org/10.1038/s41586-024-08071-yopenalex-snapshot

Transgelin 2 guards T cell lipid metabolism and antitumour function

inferred← citeshttps://doi.org/10.1038/s41590-026-02421-wopenalex-snapshot

Metabolic quiescence of naive-like memory T cells precedes and maintains antigen-specific T cell memory

inferred← citeshttps://doi.org/10.1038/s41598-023-49366-wopenalex-snapshot

Investigating the prognostic value of mTORC1 signaling in bladder cancer via bioinformatics evaluation

inferred← citeshttps://doi.org/10.1038/s41598-024-83447-8openalex-snapshot

HDAC3 inhibitors induce drug resistance by promoting IL-17 A production by T cells

inferred← citeshttps://doi.org/10.1038/s41598-025-14639-zopenalex-snapshot

Identification of new selective CD36 inhibitors to potentiate HER2-targeted therapy in HER2-positive breast cancer

inferred← citeshttps://doi.org/10.1038/s41598-025-27713-3openalex-snapshot

Genetic determinism of fatty acid composition in liver, muscle, backfat and plasma and its link to immunocompetence and performance in pigs

inferred← citeshttps://doi.org/10.1038/s41598-026-48719-5openalex-snapshot

Breast tumor microbiome regulates anti-tumor immunity and T cell-associated metabolites

inferred← citeshttps://doi.org/10.1038/s42255-026-01564-2openalex-snapshot

Ascites-derived lipid barrier at the T cell synapse

inferred← citeshttps://doi.org/10.1038/s44319-023-00038-wopenalex-snapshot

Immunosurveillance encounters cancer metabolism

inferred← citeshttps://doi.org/10.1038/s44321-024-00033-1openalex-snapshot

Identification and validation of serum metabolite biomarkers for endometrial cancer diagnosis

inferred← citeshttps://doi.org/10.1038/s44321-024-00169-0openalex-snapshot

Diagnosis and prognosis prediction of gastric cancer by high-performance serum lipidome fingerprints

inferred← citeshttps://doi.org/10.1039/d4cs00679hopenalex-snapshot

Nanomaterial-enabled metabolic reprogramming strategies for boosting antitumor immunity

inferred← citeshttps://doi.org/10.1080/08830185.2026.2687543openalex-snapshot

Metabolic alterations in the tumor microenvironment influence the anti-tumor immune function of CD8 + T cells via epigenetic modifications

inferred← citeshttps://doi.org/10.1080/2162402x.2024.2355684openalex-snapshot

Peripheral CX3CR1 + T cells combined with PD-1 blockade therapy potentiates the anti-tumor efficacy for lung cancer

inferred← citeshttps://doi.org/10.1084/jem.20221839openalex-snapshot

Nutrients: Signal 4 in T cell immunity

inferred← citeshttps://doi.org/10.1089/jmf.2023.k.0076openalex-snapshot

Subchronic Toxicity Evaluation of Idesia polycarpa Fruit Oil by 90-Day Oral Exposure in Wistar Rats

inferred← citeshttps://doi.org/10.1093/intimm/dxae007openalex-snapshot

Reprogramming T-cell metabolism to enhance adoptive cell therapies

inferred← citeshttps://doi.org/10.1093/intimm/dxag015openalex-snapshot

Lipid metabolic regulation of pathogenic type 2 immunity in the airway

inferred← citeshttps://doi.org/10.1093/lifemedi/lnaf005openalex-snapshot

Linoleic acid improves rosacea through repairing mitochondrial damage in keratinocytes

inferred← citeshttps://doi.org/10.1096/fj.202502665ropenalex-snapshot

Linoleic Acid Potentiates Response to Chemotherapy in Biliary Tract Cancer Through RARγ Activation

inferred← citeshttps://doi.org/10.1097/cm9.0000000000002989openalex-snapshot

Metabolic plasticity of T cell fate decision

inferred← citeshttps://doi.org/10.1097/cm9.0000000000003046openalex-snapshot

Targeting metabolism to improve CAR-T cells therapeutic efficacy

inferred← citeshttps://doi.org/10.1097/md.0000000000046487openalex-snapshot

Evaluating the causal role of circulating inflammatory cytokines and plasma metabolites on aplastic anemia

inferred← citeshttps://doi.org/10.1097/pn9.0000000000000072openalex-snapshot

Association of ω-3 and ω-6 polyunsaturated fatty acids with tumors: a scoping review

inferred← citeshttps://doi.org/10.1101/2023.11.16.567439openalex-snapshot

Acetyl-CoA Carboxylase Obstructs CD8 + T-Cell Lipid Utilization and Energy Synthesis in the Tumor Microenvironment

inferred← citeshttps://doi.org/10.1101/2023.12.29.23300541openalex-snapshot

Investigative needle core biopsies for multi-omics in Glioblastoma

inferred← citeshttps://doi.org/10.1101/2024.10.23.619827openalex-snapshot

Immunogenic shift of arginine metabolism triggers systemic metabolic and immunological reprogramming to prevent HER2+ breast cancer

inferred← citeshttps://doi.org/10.1101/2025.01.09.631811openalex-snapshot

Palmitate-induced mitochondrial damage restricts histone acetylation in CD8 + T cells to impair anti-tumor immunity

inferred← citeshttps://doi.org/10.1101/2025.07.11.664320openalex-snapshot

Synthesis of Cyclopropene-Modified Fatty Acids Allows Single Cell Quantification of Uptake By Immune Cells

inferred← citeshttps://doi.org/10.1111/1541-4337.70592openalex-snapshot

Unveiling the Acidic Backbone of Baijiu: A Comprehensive Review on Composition, Metabolic Pathways, and Quality Implications

inferred← citeshttps://doi.org/10.1111/cas.15999openalex-snapshot

SCD1 inhibition enhances the effector functions of CD8 + T cells via ACAT1 ‐dependent reduction of esterified cholesterol

inferred← citeshttps://doi.org/10.1111/cas.16238openalex-snapshot

Microbiota and metabolite alterations in pancreatic head and body/tail cancer patients

inferred← citeshttps://doi.org/10.1111/febs.70081openalex-snapshot

The influence of fatty acid metabolism on T cell function in lung cancer

inferred← citeshttps://doi.org/10.1111/imcb.12750openalex-snapshot

Highlight of 2023: The metabolic symphony – orchestrating T‐cell immunity

inferred← citeshttps://doi.org/10.1111/imm.70205openalex-snapshot

Linoleic Acid Enhances Murine Natural Killer Cell Function In Vitro but Compromises Mitochondrial Bioenergetic Function During Retroviral Infection

inferred← citeshttps://doi.org/10.1111/jgh.16785openalex-snapshot

Therapeutic targets for hepatocellular carcinoma identified using proteomics and Mendelian randomization

inferred← citeshttps://doi.org/10.1126/sciadv.adi2465openalex-snapshot

Inhibition of ACLY overcomes cancer immunotherapy resistance via polyunsaturated fatty acids peroxidation and cGAS-STING activation

inferred← citeshttps://doi.org/10.1126/sciadv.adj4632openalex-snapshot

TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation

inferred← citeshttps://doi.org/10.1126/sciadv.adk8093openalex-snapshot

Multi-omics analysis reveals that linoleic acid metabolism is associated with variations of trained immunity induced by distinct BCG strains

inferred← citeshttps://doi.org/10.1126/sciadv.ads8597openalex-snapshot

Targeting HMGB2 acts as dual immunomodulator by bolstering CD8 + T cell function and inhibiting tumor growth in hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1126/sciimmunol.abq2424openalex-snapshot

Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8 + T cell metabolic fitness and function in tumors

inferred← citeshttps://doi.org/10.1126/sciimmunol.ado3485openalex-snapshot

Riplet promotes lipid metabolism changes associated with CD8 T cell exhaustion and anti–PD-1 resistance in hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1126/sciimmunol.aeb1459openalex-snapshot

Palmitate-induced mitochondrial damage restricts histone acetylation in CD8 T cells to impair antitumor immunity

inferred← citeshttps://doi.org/10.1128/jvi.01700-23openalex-snapshot

Linoleic acid: a natural feed compound against porcine epidemic diarrhea disease

inferred← citeshttps://doi.org/10.1128/msystems.01549-25openalex-snapshot

Mitochondrial remodeling and metabolic reprogramming drive long-term salinity adaptation in Tetrahymena thermophila

inferred← citeshttps://doi.org/10.1136/jitc-2024-010824openalex-snapshot

Modulating lipid metabolism improves tumor immunotherapy

inferred← citeshttps://doi.org/10.1136/jitc-2026-014927openalex-snapshot

Glucose restriction reprograms lipid metabolism and enhances immunotherapy through ZNRF3-Wnt-SCD signaling axis

inferred← citeshttps://doi.org/10.1142/s0192415x24500605openalex-snapshot

Astragaloside IV Ameliorates Colonic Adenomatous Polyps Development by Orchestrating Gut Bifidobacterium and Serum Metabolome

inferred← citeshttps://doi.org/10.1146/annurev-nutr-062122-021518openalex-snapshot

The Influence of Diet on Cancer Progression and Treatment

inferred← citeshttps://doi.org/10.1155/2024/5552747openalex-snapshot

Sophora japonica Extract Inhibits Ulcerative Colitis and Colitis-Associated Colon Cancer via Regulation of Lipid Metabolism

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