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Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Probability-based protein identification by searching sequence databases using mass spectrometry data
inferredcites →https://doi.org/10.1007/978-1-4939-1164-6_10openalex-snapshot
3D Culture Assays of Murine Mammary Branching Morphogenesis and Epithelial Invasion
inferredcites →https://doi.org/10.1007/978-3-319-57127-0_3openalex-snapshot
Dividing with Extra Centrosomes: A Double Edged Sword for Cancer Cells
inferredcites →https://doi.org/10.1016/bs.mcb.2015.03.010openalex-snapshot
Studying centrosome function using three-dimensional cell cultures
inferredcites →https://doi.org/10.1016/j.bcp.2004.10.007openalex-snapshot
Inhibition of interleukin-8 (CXCL8/IL-8) responses by repertaxin, a new inhibitor of the chemokine receptors CXCR1 and CXCR2
inferredcites →https://doi.org/10.1016/j.bmcl.2007.04.016openalex-snapshot
C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists
inferredcites →https://doi.org/10.1016/j.ccell.2014.11.019openalex-snapshot
Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression
inferredcites →https://doi.org/10.1016/j.cell.2008.05.039openalex-snapshot
Centrosome Amplification Can Initiate Tumorigenesis in Flies
inferredcites →https://doi.org/10.1016/j.cell.2013.11.029openalex-snapshot
Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program
inferredcites →https://doi.org/10.1016/j.cell.2017.01.018openalex-snapshot
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
inferredcites →https://doi.org/10.1016/j.cell.2017.08.028openalex-snapshot
Putting p53 in Context
inferredcites →https://doi.org/10.1016/j.clinre.2016.12.009openalex-snapshot
Growth differentiation factor 15 promotes cell viability, invasion, migration, and angiogenesis in human liver carcinoma cell line HepG2
inferredcites →https://doi.org/10.1016/j.cmet.2016.05.010openalex-snapshot
From Ancient Pathways to Aging Cells—Connecting Metabolism and Cellular Senescence
inferredcites →https://doi.org/10.1016/j.cub.2007.07.034openalex-snapshot
DSAS-6 Organizes a Tube-like Centriole Precursor, and Its Absence Suggests Modularity in Centriole Assembly
inferredcites →https://doi.org/10.1016/j.cub.2010.05.050openalex-snapshot
Centriole Reduplication during Prolonged Interphase Requires Procentriole Maturation Governed by Plk1
inferredcites →https://doi.org/10.1016/j.cytogfr.2016.08.002openalex-snapshot
The CXCL8-CXCR1/2 pathways in cancer
inferredcites →https://doi.org/10.1016/j.devcel.2007.07.004openalex-snapshot
Regulated HsSAS-6 Levels Ensure Formation of a Single Procentriole per Centriole during the Centrosome Duplication Cycle
inferredcites →https://doi.org/10.1016/j.devcel.2016.12.022openalex-snapshot
Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals
inferredcites →https://doi.org/10.1016/j.devcel.2017.05.022openalex-snapshot
Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2006.09.030openalex-snapshot
Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2008.01.011openalex-snapshot
ROS and p53: A versatile partnership
inferredcites →https://doi.org/10.1016/j.semcdb.2013.01.003openalex-snapshot
Aneuploidy, polyploidy and ploidy reversal in the liver
inferredcites →https://doi.org/10.1016/j.tcb.2009.04.001openalex-snapshot
Centrosome function in cancer: guilty or innocent?
inferredcites →https://doi.org/10.1038/38525openalex-snapshot
A model for p53-induced apoptosis
inferredcites →https://doi.org/10.1038/nature08136openalex-snapshot
A mechanism linking extra centrosomes to chromosomal instability
inferredcites →https://doi.org/10.1038/nature10189openalex-snapshot
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
inferredcites →https://doi.org/10.1038/nature11003openalex-snapshot
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
inferredcites →https://doi.org/10.1038/nature13277openalex-snapshot
Oncogene-like induction of cellular invasion from centrosome amplification
inferredcites →https://doi.org/10.1038/nature13556openalex-snapshot
Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity
inferredcites →https://doi.org/10.1038/ncb2345openalex-snapshot
The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries
inferredcites →https://doi.org/10.1038/ncb2784openalex-snapshot
A complex secretory program orchestrated by the inflammasome controls paracrine senescence
inferredcites →https://doi.org/10.1038/ncb3169openalex-snapshot
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
inferredcites →https://doi.org/10.1038/ncb3270openalex-snapshot
Transient PLK4 overexpression accelerates tumorigenesis in p53-deficient epidermis
inferredcites →https://doi.org/10.1038/nrc3278openalex-snapshot
NRF2 and cancer: the good, the bad and the importance of context
inferredcites →https://doi.org/10.1038/nrc3339openalex-snapshot
Aiding and abetting roles of NOX oxidases in cellular transformation
inferredcites →https://doi.org/10.1038/nrc3971openalex-snapshot
Tumorigenesis: it takes a village
inferredcites →https://doi.org/10.1038/nrd4002openalex-snapshot
Modulation of oxidative stress as an anticancer strategy
inferredcites →https://doi.org/10.1038/nrm2147openalex-snapshot
p53 in health and disease
inferredcites →https://doi.org/10.1038/nrm2180openalex-snapshot
Centrosome biogenesis and function: centrosomics brings new understanding
inferredcites →https://doi.org/10.1038/s41467-018-03641-xopenalex-snapshot
Over-elongation of centrioles in cancer promotes centriole amplification and chromosome missegregation
inferredcites →https://doi.org/10.1038/s41598-017-11403-wopenalex-snapshot
Macrophages unlock progression of breast cancer cells experiencing matrigel-segregation in transplantation models
inferredcites →https://doi.org/10.1038/sj.onc.1204101openalex-snapshot
Reciprocal down-regulation of p53 and SOD2 gene expression–implication in p53 mediated apoptosis
inferredcites →https://doi.org/10.1038/srep43984openalex-snapshot
Amplified centrosomes and mitotic index display poor concordance between patient tumors and cultured cancer cells
inferredcites →https://doi.org/10.1042/bj20081386openalex-snapshot
How mitochondria produce reactive oxygen species
inferredcites →https://doi.org/10.1042/bj20110282openalex-snapshot
Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways
inferredcites →https://doi.org/10.1073/pnas.0506580102openalex-snapshot
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
inferredcites →https://doi.org/10.1073/pnas.1423344112openalex-snapshot
Empirical inference of circuitry and plasticity in a kinase signaling network
inferredcites →https://doi.org/10.1074/mcp.m113.035204openalex-snapshot
Cross-species Proteomics Reveals Specific Modulation of Signaling in Cancer and Stromal Cells by Phosphoinositide 3-kinase (PI3K) Inhibitors
inferredcites →https://doi.org/10.1083/jcb.200605036openalex-snapshot
Specificity in reactive oxidant signaling: think globally, act locally
inferredcites →https://doi.org/10.1083/jcb.201101073openalex-snapshot
Repeated cleavage failure does not establish centrosome amplification in untransformed human cells
inferredcites →https://doi.org/10.1083/jcb.201206006openalex-snapshot
p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes
inferredcites →https://doi.org/10.1083/jcb.201704102openalex-snapshot
Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells
inferredcites →https://doi.org/10.1093/nar/gki093openalex-snapshot
SPD--a web-based secreted protein database
inferredcites →https://doi.org/10.1098/rsob.150209openalex-snapshot
Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse
inferredcites →https://doi.org/10.1098/rstb.2013.0467openalex-snapshot
Causes and consequences of centrosome abnormalities in cancer
inferredcites →https://doi.org/10.1101/gad.1700908openalex-snapshot
Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes
inferredcites →https://doi.org/10.1101/gad.207027.112openalex-snapshot
The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle
inferredcites →https://doi.org/10.1101/gad.289728.116openalex-snapshot
The PIDDosome activates p53 in response to supernumerary centrosomes
inferredcites →https://doi.org/10.1126/science.8036519openalex-snapshot
Neutrophil and B Cell Expansion in Mice That Lack the Murine IL-8 Receptor Homolog
inferredcites →https://doi.org/10.1126/scisignal.2003573openalex-snapshot
Kinase-Substrate Enrichment Analysis Provides Insights into the Heterogeneity of Signaling Pathway Activation in Leukemia Cells
inferredcites →https://doi.org/10.1128/mcb.06214-11openalex-snapshot
Inhibition of Mcl-1 Promotes Senescence in Cancer Cells: Implications for Preventing Tumor Growth and Chemotherapy Resistance
inferredcites →https://doi.org/10.1152/ajpgi.00422.2005openalex-snapshot
Mechanisms of Liver Injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways
inferredcites →https://doi.org/10.1155/2015/120348openalex-snapshot
fMLP-Induced IL-8 Release Is Dependent on NADPH Oxidase in Human Neutrophils
inferredcites →https://doi.org/10.1158/1078-0432.ccr-04-0812openalex-snapshot
Increased Serum Interleukin-8 in Patients with Early and Metastatic Breast Cancer Correlates with Early Dissemination and Survival
inferredcites →https://doi.org/10.1158/1078-0432.ccr-07-4843openalex-snapshot
The Interleukin-8 Pathway in Cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-12-1063openalex-snapshot
Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-Dependent and -Independent Mechanisms
inferredcites →https://doi.org/10.1158/1535-7163.mct-15-0114-topenalex-snapshot
USP44+ Cancer Stem Cell Subclones Contribute to Breast Cancer Aggressiveness by Promoting Vasculogenic Mimicry
inferredcites →https://doi.org/10.1158/1541-7786.mcr-11-0519openalex-snapshot
Emerging Roles of Angiopoietin-like 4 in Human Cancer
inferredcites →https://doi.org/10.1186/bcr1368openalex-snapshot
Key stages in mammary gland development: The cues that regulate ductal branching morphogenesis
inferredcites →https://doi.org/10.1242/jcs.068502openalex-snapshot
Plk4 trans-autophosphorylation regulates centriole number by controlling βTrCP-mediated degradation
inferredcites →https://doi.org/10.1242/jcs.203505openalex-snapshot
Maintaining centrosomes and cilia
inferredcites →https://doi.org/10.1371/journal.pbio.0060301openalex-snapshot
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
inferredcites →https://doi.org/10.15252/embj.201798576openalex-snapshot
Structural centrosome aberrations promote non‐cell‐autonomous invasiveness
inferredcites →https://doi.org/10.18632/aging.100189openalex-snapshot
p53, ROS and senescence in the control of aging
inferredcites →https://doi.org/10.2174/1381612043453559openalex-snapshot
The Urokinase Plasminogen Activator System: Role in Malignancy
inferredcites →https://doi.org/10.2353/ajpath.2010.100129openalex-snapshot
Angiopoietin-Like 4 Interacts with Integrins β1 and β5 to Modulate Keratinocyte Migration
inferredcites →https://doi.org/10.4049/jimmunol.173.6.4197openalex-snapshot
IL-8 Is a Key Chemokine Regulating Neutrophil Recruitment in a New Mouse Model of Shigella-Induced Colitis
inferredcites →https://doi.org/10.4161/cc.22853openalex-snapshot
Identification of NCF2/p67phox as a novel p53 target gene
inferredcites →https://doi.org/10.7150/ijbs.7.1122openalex-snapshot
A Clinical Overview of Centrosome Amplification in Human Cancers

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Supernumerary Centrosome Promotes Glycogen Levels in Hepatocytes Via Metabolic Reprogramming in DEN/CCL4-Induced Mice
inferred← citeshttps://doi.org/10.1002/mco2.422openalex-snapshot
Chimeric antigen receptor natural killer cells: a promising antitumor immunotherapy
inferred← citeshttps://doi.org/10.1002/med.21924openalex-snapshot
The application of zebrafish patient‐derived xenograft tumor models in the development of antitumor agents
inferred← citeshttps://doi.org/10.1002/med.21926openalex-snapshot
Computational benchmarking of putative KIFC1 inhibitors
inferred← citeshttps://doi.org/10.1007/978-3-032-36189-9_2openalex-snapshot
The Centriole Biogenesis Cycle: Temporal Mechanisms, Autonomy and Coupling to the Cell Cycle and Other Cellular Clocks
inferred← citeshttps://doi.org/10.1007/978-981-15-4501-6_50-1openalex-snapshot
Oxidative Stress in Orchestrating Genomic Instability-Associated Cancer Progression
inferred← citeshttps://doi.org/10.1007/978-981-15-9411-3_50openalex-snapshot
Oxidative Stress in Orchestrating Genomic Instability-Associated Cancer Progression
inferred← citeshttps://doi.org/10.1007/978-981-92-0038-2_11openalex-snapshot
Zebrafish (Danio rerio): A Transparent Window into Biomedical Research
inferred← citeshttps://doi.org/10.1007/s00018-021-03928-1openalex-snapshot
Centrosome instability: when good centrosomes go bad
inferred← citeshttps://doi.org/10.1007/s00204-025-04146-5openalex-snapshot
Interplay of oxidative stress and antioxidant mechanisms in cancer development and progression
inferred← citeshttps://doi.org/10.1007/s10142-024-01392-1openalex-snapshot
Iodine-125 seed inhibits proliferation and promotes apoptosis of cholangiocarcinoma cells by inducing the ROS/p53 axis
inferred← citeshttps://doi.org/10.1007/s10555-020-09937-zopenalex-snapshot
Centrosome amplification: a quantifiable cancer cell trait with prognostic value in solid malignancies
inferred← citeshttps://doi.org/10.1007/s12072-023-10538-5openalex-snapshot
Centrosome amplification-related signature correlated with immune microenvironment and treatment response predicts prognosis and improves diagnosis of hepatocellular carcinoma by integrating machine learning and single-cell analyses
inferred← citeshttps://doi.org/10.1016/b978-0-12-821618-7.00231-5openalex-snapshot
Centrosomes and Centrioles
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2020.194488openalex-snapshot
Activating transcription factor 6 (ATF6) negatively regulates Polo-like kinase 4 expression via recruiting C/EBPβ to the upstream-promoter during ER stress
inferred← citeshttps://doi.org/10.1016/j.bbrc.2023.09.085openalex-snapshot
Advanced glycation end products initiate the mutual promoting cycle between centrosome amplification and the release of inflammatory cytokines in human vascular endothelial cells
inferred← citeshttps://doi.org/10.1016/j.biopha.2020.110924openalex-snapshot
A look into the link between centrosome amplification and breast cancer
inferred← citeshttps://doi.org/10.1016/j.biosystems.2026.105929openalex-snapshot
Stress-driven strategic games in cancer
inferred← citeshttps://doi.org/10.1016/j.canlet.2021.08.038openalex-snapshot
TEC kinase stabilizes PLK4 to promote liver cancer metastasis
inferred← citeshttps://doi.org/10.1016/j.ccell.2019.12.012openalex-snapshot
Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer
inferred← citeshttps://doi.org/10.1016/j.ccell.2020.01.009openalex-snapshot
Dynamic ROS Regulation by TIGAR: Balancing Anti-cancer and Pro-metastasis Effects
inferred← citeshttps://doi.org/10.1016/j.ccell.2020.06.001openalex-snapshot
Oxidative Stress in Cancer
inferred← citeshttps://doi.org/10.1016/j.cell.2023.04.026openalex-snapshot
Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111728openalex-snapshot
BRAFV600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.112562openalex-snapshot
ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis
inferred← citeshttps://doi.org/10.1016/j.cub.2020.03.013openalex-snapshot
Centriole Number and the Accumulation of Microtubules Modulate the Timing of Apical Insertion during Radial Intercalation
inferred← citeshttps://doi.org/10.1016/j.cub.2021.01.028openalex-snapshot
Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption
inferred← citeshttps://doi.org/10.1016/j.cub.2021.01.057openalex-snapshot
Cancer biology: Messages in extracellular vesicles depend on centrosome number
inferred← citeshttps://doi.org/10.1016/j.devcel.2019.04.002openalex-snapshot
The Emerging Link between Centrosome Aberrations and Metastasis
inferred← citeshttps://doi.org/10.1016/j.gendis.2025.101606openalex-snapshot
Age-related and postmenopausal breast cancer progression and treatment management: The significance of pro-inflammatory cytokines and CXC chemokines
inferred← citeshttps://doi.org/10.1016/j.isci.2022.104217openalex-snapshot
Tumor cell malignancy: A complex trait built through reciprocal interactions between tumors and tissue-body system
inferred← citeshttps://doi.org/10.1016/j.lfs.2021.119954openalex-snapshot
TAD1822-7 induces ROS-mediated apoptosis of HER2 positive breast cancer by decreasing E-cadherin in an EphB4 dependent manner
inferred← citeshttps://doi.org/10.1016/j.molmed.2020.01.011openalex-snapshot
The Centrosome Linker and Its Role in Cancer and Genetic Disorders
inferred← citeshttps://doi.org/10.1016/j.sbi.2020.09.011openalex-snapshot
Centrosomes in disease: how the same music can sound so different?
inferred← citeshttps://doi.org/10.1016/j.semcdb.2020.04.019openalex-snapshot
Centrosome dysfunction in human diseases
inferred← citeshttps://doi.org/10.1016/j.tcb.2020.03.002openalex-snapshot
The Complex Interplay between Antioxidants and ROS in Cancer
inferred← citeshttps://doi.org/10.1016/j.tcb.2025.02.009openalex-snapshot
Centrosomes and cancer: balancing tumor-promoting and inhibitory roles
inferred← citeshttps://doi.org/10.1016/j.trecan.2020.03.012openalex-snapshot
Zebrafish Xenografts for Drug Discovery and Personalized Medicine
inferred← citeshttps://doi.org/10.1016/j.ymthe.2025.01.043openalex-snapshot
Centrosome protein TAX1BP2 mediates STING-dependent immune response and potentiates anti-PD-1 efficacy in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1021/acsnano.3c09924openalex-snapshot
Antitumor Effects of Carrier-Free Functionalized Lignin Materials on Human Hepatocellular Carcinoma (HepG2) Cells
inferred← citeshttps://doi.org/10.1038/s41392-020-00214-7openalex-snapshot
Centrosome dysfunction: a link between senescence and tumor immunity
inferred← citeshttps://doi.org/10.1038/s41419-021-03467-4openalex-snapshot
Oncosuppressive functions of PIDD1 in response to centrosome amplification
inferred← citeshttps://doi.org/10.1038/s41419-023-05618-1openalex-snapshot
Polo-like kinase 4 (Plk4) potentiates anoikis-resistance of p53KO mammary epithelial cells by inducing a hybrid EMT phenotype
inferred← citeshttps://doi.org/10.1038/s41467-023-41840-3openalex-snapshot
Molecular landscape and functional characterization of centrosome amplification in ovarian cancer
inferred← citeshttps://doi.org/10.1038/s41467-024-53222-4openalex-snapshot
Centrioles are frequently amplified in early B cell development but dispensable for humoral immunity
inferred← citeshttps://doi.org/10.1038/s41467-026-74702-9openalex-snapshot
Sensing centrosome amplification: the interface between centriole duplication and autophagy
inferred← citeshttps://doi.org/10.1038/s41568-021-00435-0openalex-snapshot
The role of ROS in tumour development and progression
inferred← citeshttps://doi.org/10.1038/s41580-025-00921-5openalex-snapshot
Critical constituents and assembly principles of centriole biogenesis in human cells
inferred← citeshttps://doi.org/10.1038/s41598-020-65975-1openalex-snapshot
Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion
inferred← citeshttps://doi.org/10.1038/s41598-021-81383-5openalex-snapshot
Co-administration of lipopolysaccharide and d-galactosamine induces genotoxicity in mouse liver
inferred← citeshttps://doi.org/10.1038/s41598-023-29712-8openalex-snapshot
Epigenetic alterations impede epithelial-mesenchymal transition by modulating centrosome amplification and Myc/RAS axis in triple negative breast cancer cells
inferred← citeshttps://doi.org/10.1038/s42003-021-02887-4openalex-snapshot
Centrosome dysfunction associated with somatic expression of the synaptonemal complex protein TEX12
inferred← citeshttps://doi.org/10.1038/s43856-025-00967-8openalex-snapshot
Selective identification of polyploid hepatocellular carcinomas with poor prognosis by artificial intelligence-based pathological image recognition
inferred← citeshttps://doi.org/10.1038/s44319-024-00260-0openalex-snapshot
Amplified centrosomes—more than just a threat
inferred← citeshttps://doi.org/10.1038/s44319-024-00361-wopenalex-snapshot
OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival
inferred← citeshttps://doi.org/10.1042/bcj20200525openalex-snapshot
PARP-1 activation after oxidative insult promotes energy stress-dependent phosphorylation of YAP1 and reduces cell viability
inferred← citeshttps://doi.org/10.1042/bst20190034openalex-snapshot
Targeting centrosome amplification, an Achilles' heel of cancer
inferred← citeshttps://doi.org/10.1042/bst20211186openalex-snapshot
PIDD1 in cell cycle control, sterile inflammation and cell death
inferred← citeshttps://doi.org/10.1073/pnas.2416076121openalex-snapshot
Regulation of ROS signaling by TIGAR induces cancer-modulating responses in the tumor microenvironment
inferred← citeshttps://doi.org/10.1080/09553002.2022.2063432openalex-snapshot
Overexpression of TIGAR and HO-1 in peripheral blood mononuclear cells (PBMCs) of breast cancer patients treated with radiotherapy
inferred← citeshttps://doi.org/10.1080/10715762.2019.1623398openalex-snapshot
The impact of aneuploidy on cellular homeostasis
inferred← citeshttps://doi.org/10.1083/jcb.202001060openalex-snapshot
Susana Godinho: Placing cell biology at the center of cancer research
inferred← citeshttps://doi.org/10.1083/jcb.202107134openalex-snapshot
Multiple centrosomes enhance migration and immune cell effector functions of mature dendritic cells
inferred← citeshttps://doi.org/10.1083/jcb.202301092openalex-snapshot
Centrosomal organization of Cep152 provides flexibility in Plk4 and procentriole positioning
inferred← citeshttps://doi.org/10.1089/ars.2019.7891openalex-snapshot
The Potent Antioxidant MitoQ Protects Against Preeclampsia During Late Gestation but Increases the Risk of Preeclampsia When Administered in Early Pregnancy
inferred← citeshttps://doi.org/10.1091/mbc.e18-10-0674openalex-snapshot
CEP135 isoform dysregulation promotes centrosome amplification in breast cancer cells
inferred← citeshttps://doi.org/10.1093/carcin/bgaf067openalex-snapshot
Polo-like kinase 4 (PLK4) as a therapeutic target in breast cancer
inferred← citeshttps://doi.org/10.1097/bs9.0000000000000127openalex-snapshot
Centrosome Defects in Hematological Malignancies: Molecular Mechanisms and Therapeutic Insights
inferred← citeshttps://doi.org/10.1101/2020.01.24.918615openalex-snapshot
Patterns of selection against centrosome amplification in human cell lines
inferred← citeshttps://doi.org/10.1101/2022.11.16.516801openalex-snapshot
Inhibition of Centrosome Clustering Reduces Cystogenesis and Improves Kidney Function in Autosomal Dominant Polycystic Kidney Disease
inferred← citeshttps://doi.org/10.1101/2022.12.16.520613openalex-snapshot
Polo-like kinase 4 (Plk4) potentiates anoikis -resistance of p53KO mammary epithelial cells by inducing a hybrid EMT phenotype
inferred← citeshttps://doi.org/10.1101/2023.03.11.532189openalex-snapshot
Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathway
inferred← citeshttps://doi.org/10.1101/2023.03.13.532472openalex-snapshot
High prevalence and dependence of centrosome clustering in mesenchymal tumors and leukemia
inferred← citeshttps://doi.org/10.1101/2023.07.28.550973openalex-snapshot
Centrosome amplification primes for apoptosis and favors the response to chemotherapy in ovarian cancer beyond multipolar divisions
inferred← citeshttps://doi.org/10.1101/2024.02.14.580240openalex-snapshot
Exact centriole counts are critical for B cell development but not function
inferred← citeshttps://doi.org/10.1101/2024.02.15.580424openalex-snapshot
Adaptation of human cell populations to different levels of centriole amplification
inferred← citeshttps://doi.org/10.1101/509869openalex-snapshot
A pseudo-meiotic centrosomal function of TEX12 in cancer
inferred← citeshttps://doi.org/10.1101/623983openalex-snapshot
Low centrosome numbers correlate with higher aggressivity in ovarian cancer
inferred← citeshttps://doi.org/10.1111/acel.13766openalex-snapshot
The variant senescence‐associated secretory phenotype induced by centrosome amplification constitutes a pathway that activates hypoxia‐inducible factor ‐1α
inferred← citeshttps://doi.org/10.1134/s0026893324700031openalex-snapshot
Zebrafish Xenographs in Oncology and Personalized Medicine
inferred← citeshttps://doi.org/10.1134/s2635167624602274openalex-snapshot
Increase in the Intensity of Free Radical Processes of Tumor Cells by Silver Bisilicate Nanoparticles
inferred← citeshttps://doi.org/10.1146/annurev-cellbio-120219-051400openalex-snapshot
Biophysical and Quantitative Principles of Centrosome Biogenesis and Structure
inferred← citeshttps://doi.org/10.1158/1535-7163.mct-19-0957openalex-snapshot
A Highly Potent TACC3 Inhibitor as a Novel Anticancer Drug Candidate
inferred← citeshttps://doi.org/10.1158/2326-6066.cir-22-0872openalex-snapshot
Glioblastoma Vascular Plasticity Limits Effector T-cell Infiltration and Is Blocked by cAMP Activation
inferred← citeshttps://doi.org/10.1158/2767-9764.crc-22-0010openalex-snapshot
Increased Microtubule Growth Triggered by Microvesicle-mediated Paracrine Signaling is Required for Melanoma Cancer Cell Invasion
inferred← citeshttps://doi.org/10.1172/jci.insight.172047openalex-snapshot
Inhibiting centrosome clustering reduces cystogenesis and improves kidney function in autosomal dominant polycystic kidney disease
inferred← citeshttps://doi.org/10.1172/jci176879openalex-snapshot
Should I stay or should I go? Transsulfuration influences invasion and growth in glioblastoma
inferred← citeshttps://doi.org/10.1186/s12964-026-02865-5openalex-snapshot
Stress adaptation pathways and HA–CD44 signaling maintain the survival of pancreatic cancer cells with centrosome amplification
inferred← citeshttps://doi.org/10.1186/s12967-023-04498-5openalex-snapshot
Mitochondrial dysfunction at the crossroad of cardiovascular diseases and cancer
inferred← citeshttps://doi.org/10.1186/s13008-022-00077-0openalex-snapshot
An updated view on the centrosome as a cell cycle regulator
inferred← citeshttps://doi.org/10.1186/s13578-021-00557-wopenalex-snapshot
Centrosome-phagy: implications for human diseases
inferred← citeshttps://doi.org/10.1242/jcs.229765openalex-snapshot
Meeting report – Building the Cell 2018
inferred← citeshttps://doi.org/10.1242/jcs.261150openalex-snapshot
Centrosome amplification promotes cell invasion via cell–cell contact disruption and Rap-1 activation
inferred← citeshttps://doi.org/10.1371/journal.pbio.3002759openalex-snapshot
Centrosome amplification primes ovarian cancer cells for apoptosis and potentiates the response to chemotherapy
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1006832openalex-snapshot
Pan-cancer association of a centrosome amplification gene expression signature with genomic alterations and clinical outcome
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1008765openalex-snapshot
Patterns of selection against centrosome amplification in human cell lines
inferred← citeshttps://doi.org/10.1371/journal.pgen.1011460openalex-snapshot
STIL overexpression shortens lifespan and reduces tumor formation in mice
inferred← citeshttps://doi.org/10.15252/embj.2020104844openalex-snapshot
Centriolar distal appendages activate the centrosome‐PIDDosome‐p53 signalling axis via ANKRD26
inferred← citeshttps://doi.org/10.15252/embj.2020105106openalex-snapshot
ANKRD26 recruits PIDD1 to centriolar distal appendages to activate the PIDDosome following centrosome amplification
inferred← citeshttps://doi.org/10.15252/embj.2022112812openalex-snapshot
Centrosome amplification fine tunes tubulin acetylation to differentially control intracellular organization
inferred← citeshttps://doi.org/10.15252/embj.2023113510openalex-snapshot
Extra centrosomes induce PIDD1‐mediated inflammation and immunosurveillance
inferred← citeshttps://doi.org/10.15252/emmm.202215670openalex-snapshot
A catalog of numerical centrosome defects in epithelial ovarian cancers
inferred← citeshttps://doi.org/10.21203/rs.3.rs-83155/v1openalex-snapshot
Amplified centrosomes in dendritic cells promote immune cell effector functions
inferred← citeshttps://doi.org/10.31857/s0026898424030032openalex-snapshot
Zebrafish xenographs in oncology and personalized medicine
inferred← citeshttps://doi.org/10.32657/10220/48003openalex-snapshot
Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects
inferred← citeshttps://doi.org/10.3389/fcell.2023.1210983openalex-snapshot
The fate of extra centrosomes in newly formed tetraploid cells: should I stay, or should I go?
inferred← citeshttps://doi.org/10.3389/fcell.2026.1877870openalex-snapshot
The roles of centrosome amplification in diabetes-associated diseases
inferred← citeshttps://doi.org/10.3389/fimmu.2022.950884openalex-snapshot
CEP192 is a novel prognostic marker and correlates with the immune microenvironment in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.3389/fmicb.2020.01722openalex-snapshot
Crosstalk Between Pheromone Signaling and NADPH Oxidase Complexes Coordinates Fungal Developmental Processes
inferred← citeshttps://doi.org/10.3390/antiox10010128openalex-snapshot
Comprehensive Review of Methodology to Detect Reactive Oxygen Species (ROS) in Mammalian Species and Establish Its Relationship with Antioxidants and Cancer
inferred← citeshttps://doi.org/10.3390/biology10040252openalex-snapshot
The Zebrafish Xenograft Models for Investigating Cancer and Cancer Therapeutics
inferred← citeshttps://doi.org/10.3390/cancers14020442openalex-snapshot
Keep Calm and Carry on with Extra Centrosomes
inferred← citeshttps://doi.org/10.3390/cancers17182983openalex-snapshot
Development and Validation of a Centrosome Amplification-Related Prognostic Model in Pancreatic Cancer: Multi-Omics Guided Risk Stratification and Tumor Microenvironment
inferred← citeshttps://doi.org/10.3390/cells9061395openalex-snapshot
Microtubule Organization in Striated Muscle Cells
inferred← citeshttps://doi.org/10.3390/genes11080842openalex-snapshot
The Function of BARD1 in Centrosome Regulation in Cooperation with BRCA1/OLA1/RACK1
inferred← citeshttps://doi.org/10.3390/genes12040558openalex-snapshot
Karyotype Aberrations in Action: The Evolution of Cancer Genomes and the Tumor Microenvironment
inferred← citeshttps://doi.org/10.3390/ijms27156887openalex-snapshot
On the Edge of Benefit and Harm: Reactive Oxygen Species in Cancer
inferred← citeshttps://doi.org/10.3390/molecules29215181openalex-snapshot
A Novel Benzothiazole-Based Fluorescent AIE Probe for the Detection of Hydrogen Peroxide in Living Cells
inferred← citeshttps://doi.org/10.53846/goediss-8834openalex-snapshot
Investigation of the role of microtubule dynamics in paracrine signaling and cell invasion in human cancer cells
inferred← citeshttps://doi.org/10.5483/bmbrep.2023-0025openalex-snapshot
Expanding roles of centrosome abnormalities in cancers
inferred← citeshttps://doi.org/10.64898/2026.09.18.752689openalex-snapshot
Lack of centrosomes limits the epithelial-to-mesenchymal transition in human mammary cells
inferred← citeshttps://doi.org/10.70675/9023fab1z003az407bz9b02z2054939e787dopenalex-snapshot
Influence of centrosome amplification on the response to chemotherapy in epithelial ovarian cancer
inferred← citeshttps://doi.org/10.70675/f9e43816z32a2z48eez9ae4zb22feb940d3dopenalex-snapshot
Validation de biomarqueurs prédictifs de la réponse au traitement : extension des courbes de prédictivités à un critère de jugement censuré
inferred← citeshttps://doi.org/10.7554/elife.65672openalex-snapshot
Myogenin controls via AKAP6 non-centrosomal microtubule-organizing center formation at the nuclear envelope
inferred← citeshttps://doi.org/10.7554/elife.73944openalex-snapshot
Global cellular response to chemical perturbation of PLK4 activity and abnormal centrosome number
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