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Mass Spectrometry Imaging in Drug Development

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Trafficking and localization of platinum complexes in cisplatin‐resistant cell lines monitored by fluorescence‐labeled platinum

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Direct imaging of single cells and tissue at sub‐cellular spatial resolution using transmission geometry MALDI MS

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A derivatization and validation strategy for determining the spatial localization of endogenous amine metabolites in tissues using MALDI imaging mass spectrometry

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Protein and peptides in pictures: Imaging with MALDI mass spectrometry

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Microscopic imaging mass spectrometry assisted by on‐tissue chemical derivatization for visualizing multiple amino acids in human colon cancer xenografts

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Visualization and quantification of cerebral metabolic fluxes of glucose in awake mice

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A new look at drugs targeting malignant melanoma—An application for mass spectrometry imaging

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Examination of the distribution of the bioreductive drug AQ4N and its active metabolite AQ4 in solid tumours by imaging matrix‐assisted laser desorption/ionisation mass spectrometry

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Liquid extraction surface analysis mass spectrometry (LESA‐MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example

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The significance of ambient‐temperature on pharmaceutical and endogenous compound abundance and distribution in tissues sections when analyzed by matrix‐assisted laser desorption/ionization mass spectrometry imaging

inferredcites →https://doi.org/10.1002/rcm.6775openalex-snapshot

Whole‐body tissue distribution study of drugs in neonate mice using desorption electrospray ionization mass spectrometry imaging

inferredcites →https://doi.org/10.1002/sia.3529openalex-snapshot

Characterizing in situ Glycerophospholipids with SIMS and MALDI Methodologies

inferredcites →https://doi.org/10.1007/978-1-60761-746-4_20openalex-snapshot

Specific MALDI-MSI: TAG-MASS

inferredcites →https://doi.org/10.1007/978-1-60761-746-4_23openalex-snapshot

Applications of MALDI-MSI to Pharmaceutical Research

inferredcites →https://doi.org/10.1007/978-1-60761-746-4_6openalex-snapshot

Quantitative Imaging of Chemical Composition in Single Cells by Secondary Ion Mass Spectrometry: Cisplatin Affects Calcium Stores in Renal Epithelial Cells

inferredcites →https://doi.org/10.1007/s00216-011-5562-6openalex-snapshot

Improved sample preparation for MALDI–MSI of endogenous compounds in skin tissue sections and mapping of exogenous active compounds subsequent to ex-vivo skin penetration

inferredcites →https://doi.org/10.1007/s00216-013-6811-7openalex-snapshot

Localisation and quantification of benzalkonium chloride in eye tissue by TOF-SIMS imaging and liquid chromatography mass spectrometry

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Quantification in MALDI-MS imaging: what can we learn from MALDI-selected reaction monitoring and what can we expect for imaging?

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Localization of cholesterol, amyloid and glia in Alzheimer’s disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and immunofluorescence imaging

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Imaging Mass Spectrometry for Visualization of Drug and Endogenous Metabolite Distribution: Toward In Situ Pharmacometabolomes

inferredcites →https://doi.org/10.1007/s13361-011-0150-8openalex-snapshot

Reagent Precoated Targets for Rapid In-Tissue Derivatization of the Anti-Tuberculosis Drug Isoniazid Followed by MALDI Imaging Mass Spectrometry

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Imaging of Phospholipids in Formalin Fixed Rat Brain Sections by Matrix Assisted Laser Desorption/Ionization Mass Spectrometry

inferredcites →https://doi.org/10.1016/j.addr.2013.03.006openalex-snapshot

Imaging mass spectrometry: From tissue sections to cell cultures

inferredcites →https://doi.org/10.1016/j.addr.2013.04.009openalex-snapshot

Qualitative and quantitative mass spectrometry imaging of drugs and metabolites

inferredcites →https://doi.org/10.1016/j.ajpath.2011.08.032openalex-snapshot

MALDI Imaging Identifies Prognostic Seven-Protein Signature of Novel Tissue Markers in Intestinal-Type Gastric Cancer

inferredcites →https://doi.org/10.1016/j.chroma.2010.01.033openalex-snapshot

A concise review of mass spectrometry imaging

inferredcites →https://doi.org/10.1016/j.coph.2013.06.003openalex-snapshot

Imaging mass spectrometry: challenges in visualization of drug distribution in solid tumors

inferredcites →https://doi.org/10.1016/j.ijms.2006.08.003openalex-snapshot

Development of capabilities for imaging mass spectrometry under ambient conditions with desorption electrospray ionization (DESI)

inferredcites →https://doi.org/10.1016/j.jasms.2009.12.014openalex-snapshot

Quantitative MALDI-MSnanalysis of cocaine in the autopsied brain of a human cocaine user employing a wide isolation window and internal standards

inferredcites →https://doi.org/10.1016/j.jconrel.2012.04.017openalex-snapshot

MALDI-TOF MS imaging of controlled release implants

inferredcites →https://doi.org/10.1016/j.jhazmat.2014.03.046openalex-snapshot

Development and validation of TOF-SIMS and CLSM imaging method for cytotoxicity study of ZnO nanoparticles in HaCaT cells

inferredcites →https://doi.org/10.1016/j.jpba.2013.02.036openalex-snapshot

Foreign matter identification from solid dosage forms

inferredcites →https://doi.org/10.1016/j.jprot.2011.03.019openalex-snapshot

Drug localization in different lung cancer phenotypes by MALDI mass spectrometry imaging

inferredcites →https://doi.org/10.1016/j.jprot.2011.04.013openalex-snapshot

Protein signatures for survival and recurrence in metastatic melanoma

inferredcites →https://doi.org/10.1016/j.jprot.2012.02.011openalex-snapshot

In situ metabolomic mass spectrometry imaging: Recent advances and difficulties

inferredcites →https://doi.org/10.1016/j.jprot.2012.02.012openalex-snapshot

MALDI imaging mass spectrometry reveals COX7A2, TAGLN2 and S100-A10 as novel prognostic markers in Barrett's adenocarcinoma

inferredcites →https://doi.org/10.1016/j.jprot.2012.04.012openalex-snapshot

Sample preparation for mass spectrometry imaging: Small mistakes can lead to big consequences

inferredcites →https://doi.org/10.1016/j.jprot.2012.07.028openalex-snapshot

Mass spectrometry imaging for drug distribution studies

inferredcites →https://doi.org/10.1016/j.jprot.2012.07.034openalex-snapshot

Novel mass spectrometry imaging software assisting labeled normalization and quantitation of drugs and neuropeptides directly in tissue sections

inferredcites →https://doi.org/10.1016/j.jprot.2012.07.035openalex-snapshot

Quantitative mass spectrometry imaging of propranolol and olanzapine using tissue extinction calculation as normalization factor

inferredcites →https://doi.org/10.1016/j.jvs.2013.01.033openalex-snapshot

Cilostazol inhibits accumulation of triglycerides in a rat model of carotid artery ligation

inferredcites →https://doi.org/10.1016/j.mad.2004.09.032openalex-snapshot

MALDI mass spectrometric imaging of biological tissue sections

inferredcites →https://doi.org/10.1016/j.nbd.2009.07.030openalex-snapshot

Structure and function of the blood–brain barrier

inferredcites →https://doi.org/10.1016/j.neuron.2014.10.011openalex-snapshot

Direct Targeted Quantitative Molecular Imaging of Neurotransmitters in Brain Tissue Sections

inferredcites →https://doi.org/10.1016/j.nicl.2013.04.015openalex-snapshot

Identification of promethazine as an amyloid-binding molecule using a fluorescence high-throughput assay and MALDI imaging mass spectrometry

inferredcites →https://doi.org/10.1016/j.pbiomolbio.2005.05.011openalex-snapshot

ACE2: A novel therapeutic target for cardiovascular diseases

inferredcites →https://doi.org/10.1016/j.pharmthera.2009.03.017openalex-snapshot

Drug interactions at the blood-brain barrier: Fact or fantasy?☆

inferredcites →https://doi.org/10.1016/j.vascn.2006.11.004openalex-snapshot

Utility of imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization (MALDI) on an ion trap mass spectrometer in the analysis of drugs and metabolites in biological tissues

inferredcites →https://doi.org/10.1016/j.vascn.2010.10.003openalex-snapshot

Utility of quantitative whole-body autoradiography (QWBA) and imaging mass spectrometry (IMS) by matrix-assisted laser desorption/ionization (MALDI) in the assessment of ocular distribution of drugs

inferredcites →https://doi.org/10.1016/j.ymeth.2011.03.007openalex-snapshot

Investigation of protein induction in tumour vascular targeted strategies by MALDI MSI

inferredcites →https://doi.org/10.1016/s0026-895x(24)09232-0openalex-snapshot

Is Cisplatin-Induced Cell Death Always Produced by Apoptosis?

inferredcites →https://doi.org/10.1016/s1044-0305(99)00103-8openalex-snapshot

Detection of pharmaceutical compounds in tissue by matrix-assisted laser desorption/ionization and laser desorption/chemical ionization tandem mass spectrometry with a quadrupole ion trap

inferredcites →https://doi.org/10.1021/ac071301vopenalex-snapshot

Mass Imaging and Identification of Biomolecules with MALDI-QIT-TOF-Based System

inferredcites →https://doi.org/10.1021/ac101998zopenalex-snapshot

Ultrahighly Sensitive in Situ Metabolomic Imaging for Visualizing Spatiotemporal Metabolic Behaviors

inferredcites →https://doi.org/10.1021/ac1029049openalex-snapshot

High-Sensitivity MALDI-MRM-MS Imaging of Moxifloxacin Distribution in Tuberculosis-Infected Rabbit Lungs and Granulomatous Lesions

inferredcites →https://doi.org/10.1021/ac200610copenalex-snapshot

Single Hair Cocaine Consumption Monitoring by Mass Spectrometric Imaging

inferredcites →https://doi.org/10.1021/ac2014349openalex-snapshot

Direct Demonstration of Tissue Uptake of an Inhaled Drug: Proof-of-Principle Study Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging

inferredcites →https://doi.org/10.1021/ac202630topenalex-snapshot

Qualitative and Quantitative MALDI Imaging of the Positron Emission Tomography Ligands Raclopride (a D2 Dopamine Antagonist) and SCH 23390 (a D1 Dopamine Antagonist) in Rat Brain Tissue Sections Using a Solvent-Free Dry Matrix Application Method

inferredcites →https://doi.org/10.1021/ac202875dopenalex-snapshot

Quantitation of Spatially-Localized Proteins in Tissue Samples using MALDI-MRM Imaging

inferredcites →https://doi.org/10.1021/ac203322qopenalex-snapshot

Controlled-pH Tissue Cleanup Protocol for Signal Enhancement of Small Molecule Drugs Analyzed by MALDI-MS Imaging

inferredcites →https://doi.org/10.1021/ac3011654openalex-snapshot

Localization and Quantification of Drugs in Animal Tissues by Use of Desorption Electrospray Ionization Mass Spectrometry Imaging

inferredcites →https://doi.org/10.1021/ac301337hopenalex-snapshot

Single Cell Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

inferredcites →https://doi.org/10.1021/ac301498mopenalex-snapshot

Deuterated Matrix-Assisted Laser Desorption Ionization Matrix Uncovers Masked Mass Spectrometry Imaging Signals of Small Molecules

inferredcites →https://doi.org/10.1021/ac302960jopenalex-snapshot

Quantitative MALDI Tandem Mass Spectrometric Imaging of Cocaine from Brain Tissue with a Deuterated Internal Standard

inferredcites →https://doi.org/10.1021/ac3029618openalex-snapshot

Identifying Tissue-Specific Signal Variation in MALDI Mass Spectrometric Imaging by Use of an Internal Standard

inferredcites →https://doi.org/10.1021/ac401595aopenalex-snapshot

Hydroxyflavones as a New Family of Matrices for MALDI Tissue Imaging

inferredcites →https://doi.org/10.1021/ac402777kopenalex-snapshot

Mass Spectrometry Imaging for Dissecting Steroid Intracrinology within Target Tissues

inferredcites →https://doi.org/10.1021/ac403924wopenalex-snapshot

Imaging of Distribution of Topically Applied Drug Molecules in Mouse Skin by Combination of Time-of-Flight Secondary Ion Mass Spectrometry and Scanning Electron Microscopy

inferredcites →https://doi.org/10.1021/ac502217ropenalex-snapshot

Mass Spectrometry Imaging of Cassette-Dosed Drugs for Higher Throughput Pharmacokinetic and Biodistribution Analysis

inferredcites →https://doi.org/10.1021/ac800617sopenalex-snapshot

MALDI-FTICR Imaging Mass Spectrometry of Drugs and Metabolites in Tissue

inferredcites →https://doi.org/10.1021/ac970888iopenalex-snapshot

Molecular Imaging of Biological Samples: Localization of Peptides and Proteins Using MALDI-TOF MS

inferredcites →https://doi.org/10.1021/cr3004295openalex-snapshot

Analysis of Tissue Specimens by Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry in Biological and Clinical Research

inferredcites →https://doi.org/10.1021/mp3004308openalex-snapshot

Quantitative Targeted Absolute Proteomic Analysis of Transporters, Receptors and Junction Proteins for Validation of Human Cerebral Microvascular Endothelial Cell Line hCMEC/D3 as a Human Blood–Brain Barrier Model

inferredcites →https://doi.org/10.1021/pr050281fopenalex-snapshot

Decreased Striatal Levels of PEP-19 Following MPTP Lesion in the Mouse

inferredcites →https://doi.org/10.1021/pr400581bopenalex-snapshot

Experimental Models to Study Drug Distributions in Tissue Using MALDI Mass Spectrometry Imaging

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Determination of Spatial Distribution of Melamine−Cyanuric Acid Crystals in Rat Kidney Tissue by Histology and Imaging Matrix-Assisted Laser Desorption/Ionization Quadrupole Time-of-Flight Mass Spectrometry

inferredcites →https://doi.org/10.1038/86573openalex-snapshot

Imaging mass spectrometry: A new technology for the analysis of protein expression in mammalian tissues

inferredcites →https://doi.org/10.1038/clpt.2012.240openalex-snapshot

Intracellular Drug Concentrations

inferredcites →https://doi.org/10.1038/jcbfm.2012.126openalex-snapshot

Drug Transport across the Blood–Brain Barrier

inferredcites →https://doi.org/10.1038/nm.3488openalex-snapshot

Multiplexed ion beam imaging of human breast tumors

inferredcites →https://doi.org/10.1038/npp.2013.215openalex-snapshot

Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology

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Proteomic analysis of formalin-fixed paraffin-embedded tissue by MALDI imaging mass spectrometry

inferredcites →https://doi.org/10.1038/nrd1007openalex-snapshot

Molecular imaging in drug discovery and development

inferredcites →https://doi.org/10.1038/nrd2290openalex-snapshot

Molecular imaging in drug development

inferredcites →https://doi.org/10.1038/nrd3028openalex-snapshot

Membrane transporters in drug development

inferredcites →https://doi.org/10.1038/scientificamerican0794-58openalex-snapshot

Barriers to Drug Delivery in Solid Tumors

inferredcites →https://doi.org/10.1038/srep02859openalex-snapshot

Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging

inferredcites →https://doi.org/10.1038/srep03050openalex-snapshot

The significance of microscopic mass spectrometry with high resolution in the visualisation of drug distribution

inferredcites →https://doi.org/10.1039/c2an35782hopenalex-snapshot

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Lipid imaging by mass spectrometry – a review

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Discrimination of lymph node metastases using desorption electrospray ionisation-mass spectrometry imaging

inferredcites →https://doi.org/10.1039/c4mt00131aopenalex-snapshot

Complementarity of MALDI and LA ICP mass spectrometry for platinum anticancer imaging in human tumor

inferredcites →https://doi.org/10.1051/medsci/2007231s31openalex-snapshot

Imagerie MALDI

inferredcites →https://doi.org/10.1063/1.1709314openalex-snapshot

Ion Microprobe Mass Analyzer

inferredcites →https://doi.org/10.1073/pnas.0801066105openalex-snapshot

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inferredcites →https://doi.org/10.1073/pnas.1310524111openalex-snapshot

Chemo-informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer

inferredcites →https://doi.org/10.1074/jbc.r111.225854openalex-snapshot

Imaging of Intact Tissue Sections: Moving beyond the Microscope

inferredcites →https://doi.org/10.1074/mcp.m500399-mcp200openalex-snapshot

Biomarker Discovery by Imaging Mass Spectrometry

inferredcites →https://doi.org/10.1089/ars.2010.3290openalex-snapshot

Paradoxical ATP Elevation in Ischemic Penumbra Revealed by Quantitative Imaging Mass Spectrometry

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Safety Evaluation of Sunscreen Formulations Containing Titanium Dioxide and Zinc Oxide Nanoparticles in UVB Sunburned Skin: An In Vitro and In Vivo Study

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ACE2: A New Target for Cardiovascular Disease Therapeutics

inferredcites →https://doi.org/10.1111/cas.12221openalex-snapshot

Accumulated phosphatidylcholine (16:0/16:1) in human colorectal cancer; possible involvement of LPCAT 4

inferredcites →https://doi.org/10.1111/cas.12229openalex-snapshot

High‐resolution imaging mass spectrometry reveals detailed spatial distribution of phosphatidylinositols in human breast cancer

inferredcites →https://doi.org/10.1111/j.1365-2818.1981.tb02475.xopenalex-snapshot

The use of propane/isopentane mixtures for rapid freezing of biological specimens

inferredcites →https://doi.org/10.1111/j.1471-4159.2008.05720.xopenalex-snapshot

ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood–brain barrier

inferredcites →https://doi.org/10.1111/j.1476-5381.2010.01127.xopenalex-snapshot

Principles of early drug discovery

inferredcites →https://doi.org/10.1124/dmd.114.057513openalex-snapshot

Distribution of the Phosphatidylinositol 3-Kinase Inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 Intracranial Glioblastoma Models—Assessment by Matrix-Assisted Laser Desorption Ionization Imaging

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Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization

inferredcites →https://doi.org/10.1146/annurev-pharmtox-010510-100540openalex-snapshot

Physiologically-Based Pharmacokinetics in Drug Development and Regulatory Science

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Mass spectrometry for the molecular imaging of angiotensin metabolism in kidney

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A Molecular Imaging Primer: Modalities, Imaging Agents, and Applications

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Early Changes in Protein Expression Detected by Mass Spectrometry Predict Tumor Response to Molecular Therapeutics

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Identification of Markers of Taxane Sensitivity Using Proteomic and Genomic Analyses of Breast Tumors from Patients Receiving Neoadjuvant Paclitaxel and Radiation

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The application of cassette dosing for pharmacokinetic screening in small-molecule cancer drug discovery

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Energy Management by Enhanced Glycolysis in G1-phase in Human Colon Cancer Cells In Vitro and In Vivo

inferredcites →https://doi.org/10.1177/019262339902700108openalex-snapshot

Lesions and Identification of Crystalline Precipitates of Glycoprotein IIb-IIIa Antagonists in the Rat Kidney

inferredcites →https://doi.org/10.1208/s12248-009-9158-4openalex-snapshot

Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development

inferredcites →https://doi.org/10.1371/journal.pone.0011411openalex-snapshot

Fine Mapping the Spatial Distribution and Concentration of Unlabeled Drugs within Tissue Micro-Compartments Using Imaging Mass Spectrometry

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Visualization of Spatiotemporal Energy Dynamics of Hippocampal Neurons by Mass Spectrometry during a Kainate-Induced Seizure

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Imaging Mass Spectrometry Reveals Elevated Nigral Levels of Dynorphin Neuropeptides in L-DOPA-Induced Dyskinesia in Rat Model of Parkinson's Disease

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In Situ Mass Spectrometry Imaging and Ex Vivo Characterization of Renal Crystalline Deposits Induced in Multiple Preclinical Drug Toxicology Studies

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Determination of Paclitaxel Distribution in Solid Tumors by Nano-Particle Assisted Laser Desorption Ionization Mass Spectrometry Imaging

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Top-Down Proteomics with Mass Spectrometry Imaging: A Pilot Study towards Discovery of Biomarkers for Neurodevelopmental Disorders

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Drug and metabolite concentrations in tissues in relationship to tissue adverse findings: a review

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Strategies to assess blood–brain barrier penetration

inferredcites →https://doi.org/10.1529/biophysj.107.119800openalex-snapshot

Label-Free Calcium Imaging in Ischemic Retinal Tissue by TOF-SIMS

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Using PET Studies of P-gp Function to Elucidate Mechanisms Underlying the Disposition of Drugs

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Utility of spatially-resolved atmospheric pressure surface sampling and ionization techniques as alternatives to mass spectrometric imaging (MSI) in drug metabolism

inferredcites →https://doi.org/10.3109/03602532.2012.691099openalex-snapshot

The right compound in the right assay at the right time: an integrated discovery DMPK strategy

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MALDI–Tandem Mass Spectrometry Imaging of Astemizole and its Primary Metabolite in Rat Brain Sections

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MALDI Imaging Techniques Dedicated to Drug-Distribution Studies

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Label-Free MS Imaging from Drug Discovery to Preclinical Development

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Analysis of small molecule antibody–drug conjugate catabolites in rat liver and tumor tissue by liquid extraction surface analysis micro‐capillary liquid chromatography/tandem mass spectrometry

inferred← citeshttps://doi.org/10.1002/rcm.9110openalex-snapshot

Matrix ions as internal standard for high mass accuracy matrix‐assisted laser desorption/ionization mass spectrometry imaging

inferred← citeshttps://doi.org/10.1007/978-1-4939-7592-1_26openalex-snapshot

Mass Spectrometry Imaging of Metabolites

inferred← citeshttps://doi.org/10.1007/978-1-4939-8661-3_15openalex-snapshot

Methods and Study Designs for Characterizing the Pharmacokinetics and Pharmacodynamics of Carrier-Mediated Agents

inferred← citeshttps://doi.org/10.1007/978-3-030-51652-9_5openalex-snapshot

Single-Cell Metabolomics by Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1007/978-3-031-39094-4_13openalex-snapshot

Spatial Metabolomics Using Imaging Mass Spectrometry

inferred← citeshttps://doi.org/10.1007/978-3-031-44256-8_16openalex-snapshot

Quantitative Imaging Using SIMS

inferred← citeshttps://doi.org/10.1007/s00018-025-05715-8openalex-snapshot

Dissecting inflammation in the immunemetabolomic era

inferred← citeshttps://doi.org/10.1007/s00216-017-0443-2openalex-snapshot

Combination of MALDI-MSI and cassette dosing for evaluation of drug distribution in human skin explant

inferred← citeshttps://doi.org/10.1007/s00216-019-02151-zopenalex-snapshot

Imaging drugs, metabolites and biomarkers in rodent lung: a DESI MS strategy for the evaluation of drug-induced lipidosis

inferred← citeshttps://doi.org/10.1007/s00216-020-02595-8openalex-snapshot

Application of chemometric methods to the analysis of multimodal chemical images of biological tissues

inferred← citeshttps://doi.org/10.1007/s00216-026-06705-wopenalex-snapshot

MALDI mass spectrometry imaging across spatial scales in toxicology: tissue evidence, cellular heterogeneity, and emerging single-cell opportunities

inferred← citeshttps://doi.org/10.1007/s00216-026-06795-6openalex-snapshot

Cold solvent washing enhances AFADESI-MSI spatial lipidomics and lipid metabolism profiling in pancreatic cancer

inferred← citeshttps://doi.org/10.1007/s00775-017-1462-3openalex-snapshot

Visualization of metallodrugs in single cells by secondary ion mass spectrometry imaging

inferred← citeshttps://doi.org/10.1007/s11101-016-9482-0openalex-snapshot

In vitro metabolism studies of natural products are crucial in the early development of medicines

inferred← citeshttps://doi.org/10.1007/s11307-018-1267-yopenalex-snapshot

Mass Spectrometry Imaging and Integration with Other Imaging Modalities for Greater Molecular Understanding of Biological Tissues

inferred← citeshttps://doi.org/10.1007/s13361-015-1147-5openalex-snapshot

MALDI FTICR IMS of Intact Proteins: Using Mass Accuracy to Link Protein Images with Proteomics Data

inferred← citeshttps://doi.org/10.1007/s13361-015-1265-0openalex-snapshot

High Throughput In Situ DDA Analysis of Neuropeptides by Coupling Novel Multiplex Mass Spectrometric Imaging (MSI) with Gas-Phase Fractionation

inferred← citeshttps://doi.org/10.1007/s13361-016-1485-yopenalex-snapshot

Analysis of Chemotherapeutic Drug Delivery at the Single Cell Level Using 3D-MSI-TOF-SIMS

inferred← citeshttps://doi.org/10.1007/s13361-017-1740-xopenalex-snapshot

IR-MALDESI Mass Spectrometry Imaging at 50 Micron Spatial Resolution

inferred← citeshttps://doi.org/10.1007/s44307-024-00014-yopenalex-snapshot

Applications of mass spectrometry imaging in botanical research

inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.13815-6openalex-snapshot

Inhibiting Kinases in the CNS

inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.14608-6openalex-snapshot

Independent Component Analysis in Analytical Chemistry

inferred← citeshttps://doi.org/10.1016/b978-0-12-818998-6.00005-xopenalex-snapshot

Imaging mass spectrometry: small drugs and metabolites in tissue

inferred← citeshttps://doi.org/10.1016/b978-0-323-85158-9.00030-0openalex-snapshot

Use of SRS microscopy for imaging drugs

inferred← citeshttps://doi.org/10.1016/bs.acr.2016.11.005openalex-snapshot

Mass Spectrometry Imaging in Oncology Drug Discovery

inferred← citeshttps://doi.org/10.1016/bs.coac.2018.09.001openalex-snapshot

Ion Mobility Separation Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1016/bs.ctm.2021.10.005openalex-snapshot

Mass spectrometry-based lipid analysis and imaging

inferred← citeshttps://doi.org/10.1016/j.aca.2016.11.056openalex-snapshot

Pharmacokinetic study based on a matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight imaging mass microscope combined with a novel relative exposure approach: A case of octreotide in mouse target tissues

inferred← citeshttps://doi.org/10.1016/j.aca.2018.03.031openalex-snapshot

Novel automated workflow for spectral alignment and mass calibration in MS imaging using a sputtered Ag nanolayer

inferred← citeshttps://doi.org/10.1016/j.aca.2018.06.067openalex-snapshot

Past-in-the-Future. Peak detection improves targeted mass spectrometry imaging

inferred← citeshttps://doi.org/10.1016/j.aca.2021.339085openalex-snapshot

High-resolution imaging and identification of biomolecules using Nano-DESI coupled to ion mobility spectrometry

inferred← citeshttps://doi.org/10.1016/j.aca.2021.339337openalex-snapshot

Unraveling metabolic alterations in transgenic mouse model of Alzheimer's disease using MALDI MS imaging with 4-aminocinnoline-3-carboxamide matrix

inferred← citeshttps://doi.org/10.1016/j.addr.2021.113942openalex-snapshot

Visualizing and quantifying antimicrobial drug distribution in tissue

inferred← citeshttps://doi.org/10.1016/j.apsb.2022.11.011openalex-snapshot

Spatiotemporally resolved metabolomics and isotope tracing reveal CNS drug targets

inferred← citeshttps://doi.org/10.1016/j.bbapap.2016.12.011openalex-snapshot

Quantification of low molecular weight compounds by MALDI imaging mass spectrometry – A tutorial review

inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.109050openalex-snapshot

Characterization and bioevaluation of radioiodinated oseltamivir phosphate for inflammation imaging as a new perspective

inferred← citeshttps://doi.org/10.1016/j.cbpa.2018.05.007openalex-snapshot

Imaging and spatially resolved quantification of drug distribution in tissues by mass spectrometry

inferred← citeshttps://doi.org/10.1016/j.cbpa.2022.102199openalex-snapshot

Molecular network strategy in multi-omics and mass spectrometry imaging

inferred← citeshttps://doi.org/10.1016/j.cca.2026.121177openalex-snapshot

Matrix-assisted laser desorption/ionization mass spectrometry imaging for spatial clinical oncopathology: diagnosis, margins and therapy

inferred← citeshttps://doi.org/10.1016/j.cclet.2018.06.006openalex-snapshot

A high-performance bio-tissue imaging method using air flow-assisted desorption electrospray ionization coupled with a high-resolution mass spectrometer

inferred← citeshttps://doi.org/10.1016/j.chemphyslip.2017.11.004openalex-snapshot

MALDI imaging of enzymatic degradation of glycerides by lipase on textile surface

inferred← citeshttps://doi.org/10.1016/j.dmpk.2019.04.006openalex-snapshot

Applications of MALDI mass spectrometry imaging for pharmacokinetic studies during drug development

inferred← citeshttps://doi.org/10.1016/j.dmpk.2021.100385openalex-snapshot

A procedure for method development and protein binding ratio as the indicator of sensitivity with anticancer agents on MALDI mass spectrometry imaging

inferred← citeshttps://doi.org/10.1016/j.drudis.2022.02.018openalex-snapshot

Recent advances in metabolomics analysis for early drug development

inferred← citeshttps://doi.org/10.1016/j.drudis.2022.04.009openalex-snapshot

Multimodal molecular imaging in drug discovery and development

inferred← citeshttps://doi.org/10.1016/j.ejpb.2016.12.005openalex-snapshot

Influence of the skin barrier on the penetration of topically-applied dexamethasone probed by soft X-ray spectromicroscopy

inferred← citeshttps://doi.org/10.1016/j.ejps.2018.11.011openalex-snapshot

Visualization of the penetration modifying mechanism of laurocapram by Mass Spectrometry Imaging in buccal drug delivery

inferred← citeshttps://doi.org/10.1016/j.ijfoodmicro.2022.109675openalex-snapshot

Mass spectrometry imaging and its potential in food microbiology

inferred← citeshttps://doi.org/10.1016/j.ijms.2018.09.014openalex-snapshot

The metabolism and distribution of imidazole alkaloids from Lepidium meyenii (Maca) in mouse by matrix-assisted laser desorption/ionization mass spectrometry imaging

inferred← citeshttps://doi.org/10.1016/j.isci.2019.09.036openalex-snapshot

Detection of a High-Turnover Serotonin Circuit in the Mouse Brain Using Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1016/j.jpha.2023.04.007openalex-snapshot

Spatiotemporal pharmacometabolomics based on ambient mass spectrometry imaging to evaluate the metabolism and hepatotoxicity of amiodarone in HepG2 spheroids

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2018.01.013openalex-snapshot

A mass spectrometry imaging approach for investigating how drug-drug interactions influence drug blood-brain barrier permeability

inferred← citeshttps://doi.org/10.1016/j.talanta.2017.11.005openalex-snapshot

Quantitative analysis of drug distribution by ambient mass spectrometry imaging method with signal extinction normalization strategy and inkjet-printing technology

inferred← citeshttps://doi.org/10.1016/j.talanta.2021.122918openalex-snapshot

Quantitative measurement of pioglitazone in neoplastic and normal tissues by AP-MALDI mass spectrometry imaging

inferred← citeshttps://doi.org/10.1016/j.talanta.2022.123958openalex-snapshot

Spatial segmentation of mass spectrometry imaging data featuring selected principal components

inferred← citeshttps://doi.org/10.1016/j.talanta.2024.125858openalex-snapshot

Advancing mass spectrometry-based chemical imaging: A noncontact continuous flow surface probe in mass spectrometry for enhanced signal detection and spatial resolution

inferred← citeshttps://doi.org/10.1016/j.tips.2022.06.005openalex-snapshot

Advances in spatial mass spectrometry enable in-depth neuropharmacodynamics

inferred← citeshttps://doi.org/10.1016/j.trac.2021.116183openalex-snapshot

MALDI-MSI analysis of cancer drugs: Significance, advances, and applications

inferred← citeshttps://doi.org/10.1016/j.trac.2021.116482openalex-snapshot

Mass spectrometry imaging in drug distribution and drug metabolism studies – Principles, applications and perspectives

inferred← citeshttps://doi.org/10.1016/j.trac.2024.117878openalex-snapshot

State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants

inferred← citeshttps://doi.org/10.1016/j.trac.2025.118339openalex-snapshot

Mass spectrometry imaging techniques for characterization of novel battery materials

inferred← citeshttps://doi.org/10.1016/j.trac.2025.118356openalex-snapshot

Laser desorption/ionization target chip: a transformative platform for pharmaceutical research

inferred← citeshttps://doi.org/10.1016/j.trac.2026.118853openalex-snapshot

Evidence-driven m/z alignment in mass spectrometry imaging: Physics models, observed-data recalibration, and deep learning

inferred← citeshttps://doi.org/10.1016/j.ymeth.2016.05.021openalex-snapshot

Direct imaging of elemental distributions in tissue sections by laser ablation mass spectrometry

inferred← citeshttps://doi.org/10.1017/s1431927621013593openalex-snapshot

Cell and Tissue Imaging by TOF-SIMS and MALDI-TOF: An Overview for Biological and Pharmaceutical Analysis

inferred← citeshttps://doi.org/10.1021/acs.analchem.0c03186openalex-snapshot

Multilabel Per-Pixel Quantitation in Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1021/acs.analchem.0c03956openalex-snapshot

Quantitative Mass Spectrometry Imaging to Study Drug Distribution in the Intestine Following Oral Dosing

inferred← citeshttps://doi.org/10.1021/acs.analchem.1c00498openalex-snapshot

Hydralazine as a Versatile and Universal Matrix for High-Molecular Coverage and Dual-Polarity Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1021/acs.analchem.2c01723openalex-snapshot

Metabolic Perturbation Score-Based Mass Spectrometry Imaging Spatially Resolves a Functional Metabolic Response

inferred← citeshttps://doi.org/10.1021/acs.analchem.2c02870openalex-snapshot

Fast Mass Microscopy: Mass Spectrometry Imaging of a Gigapixel Image in 34 Minutes

inferred← citeshttps://doi.org/10.1021/acs.analchem.3c04705openalex-snapshot

Lipid Isobar and Isomer Imaging Using Nanospray Desorption Electrospray Ionization Combined with Triple Quadrupole Mass Spectrometry

inferred← citeshttps://doi.org/10.1021/acs.analchem.4c01088openalex-snapshot

Large-Scale Screening of Pharmaceutical Compounds to Explore the Application Space of On-Tissue MALDI and MALDI-2 Mass Spectrometry

inferred← citeshttps://doi.org/10.1021/acs.analchem.4c05249openalex-snapshot

Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1021/acs.analchem.4c06682openalex-snapshot

Study on the Material Basis and Mechanisms of Achyrocline satureioides in the Treatment of Nonsmall Cell Lung Cancer Based on Network Pharmacology and Spatial Metabolomics

inferred← citeshttps://doi.org/10.1021/acs.analchem.5b00842openalex-snapshot

Single-Cell Analysis: Visualizing Pharmaceutical and Metabolite Uptake in Cells with Label-Free 3D Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1021/acs.analchem.5c00157openalex-snapshot

Advances in Tandem Mass Spectrometry Imaging for Next-Generation Spatial Metabolomics

inferred← citeshttps://doi.org/10.1021/acs.analchem.5c04075openalex-snapshot

Integrating Model-Based Reconstruction and Deep Learning for Accelerating Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1021/acs.analchem.6b00672openalex-snapshot

Spatial Autocorrelation in Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1021/acs.analchem.6b02711openalex-snapshot

Aspects of Quantitation in Mass Spectrometry Imaging Investigated on Cryo-Sections of Spiked Tissue Homogenates

inferred← citeshttps://doi.org/10.1021/acs.analchem.7b00091openalex-snapshot

In Situ Hydrogel Conditioning of Tissue Samples To Enhance the Drug’s Sensitivity in Ambient Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1021/acs.analchem.7b03188openalex-snapshot

A Space Efficient Direct Access Data Compression Approach for Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1021/acs.analchem.8b01870openalex-snapshot

Drug-Homogeneity Index in Mass-Spectrometry Imaging

inferred← citeshttps://doi.org/10.1021/acs.analchem.8b02740openalex-snapshot

Toward Higher Sensitivity in Quantitative MALDI Imaging Mass Spectrometry of CNS Drugs Using a Nonpolar Matrix

inferred← citeshttps://doi.org/10.1021/acs.analchem.8b03857openalex-snapshot

Targeted Drug and Metabolite Imaging: Desorption Electrospray Ionization Combined with Triple Quadrupole Mass Spectrometry

inferred← citeshttps://doi.org/10.1021/acs.analchem.8b04762openalex-snapshot

Virtual Calibration Quantitative Mass Spectrometry Imaging for Accurately Mapping Analytes across Heterogenous Biotissue

inferred← citeshttps://doi.org/10.1021/acs.analchem.8b05598openalex-snapshot

Colocalization Features for Classification of Tumors Using Desorption Electrospray Ionization Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1021/acs.analchem.9b00803openalex-snapshot

3-Aminophthalhydrazide (Luminol) As a Matrix for Dual-Polarity MALDI MS Imaging

inferred← citeshttps://doi.org/10.1021/acs.analchem.9b02495openalex-snapshot

Enhanced Sensitivity Using MALDI Imaging Coupled with Laser Postionization (MALDI-2) for Pharmaceutical Research

inferred← citeshttps://doi.org/10.1021/acs.analchem.9b03612openalex-snapshot

High-Performance Molecular Imaging with MALDI Trapped Ion-Mobility Time-of-Flight (timsTOF) Mass Spectrometry

inferred← citeshttps://doi.org/10.1021/acs.chemrestox.5b00262openalex-snapshot

Investigating Nephrotoxicity of Polymyxin Derivatives by Mapping Renal Distribution Using Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1021/acs.jafc.2c00468openalex-snapshot

Study on Absorption, Distribution, Metabolism, and Excretion Properties of Novel Insecticidal GABA Receptor Antagonist, Pyraquinil, in Diamondback Moth Combining MALDI Mass Spectrometry Imaging and High-Resolution Mass Spectrometry

inferred← citeshttps://doi.org/10.1021/acs.jproteome.3c00167openalex-snapshot

A Guide to MALDI Imaging Mass Spectrometry for Tissues

inferred← citeshttps://doi.org/10.1021/acschemneuro.6c00199openalex-snapshot

Spatial Lipidomics Reveals Region-Specific Lipid Remodeling in Scn2a -Deficient Mouse Brain

inferred← citeshttps://doi.org/10.1021/acsnano.9b09804openalex-snapshot

Subcellular Mass Spectrometry Imaging and Absolute Quantitative Analysis across Organelles

inferred← citeshttps://doi.org/10.1021/jasms.0c00003openalex-snapshot

Development of an Integrated Tissue Pretreatment Protocol for Enhanced MALDI MS Imaging of Drug Distribution in the Brain

inferred← citeshttps://doi.org/10.1021/jasms.0c00167openalex-snapshot

High-Resolution Ion Microscope Imaging over Wide Mass Ranges Using Electrodynamic Postextraction Differential Acceleration

inferred← citeshttps://doi.org/10.1021/jasms.1c00240openalex-snapshot

Holistic Characterization of a Salmonella Typhimurium Infection Model Using Integrated Molecular Imaging

inferred← citeshttps://doi.org/10.1021/jasms.2c00271openalex-snapshot

Pyrylium-Based Derivatization for Rapid Labeling and Enhanced Detection of Cholesterol in Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1021/jasms.2c00370openalex-snapshot

MALDI IMS-Derived Molecular Contour Maps: Augmenting Histology Whole-Slide Images

inferred← citeshttps://doi.org/10.1021/jasms.4c00345openalex-snapshot

Quantitative Analysis of Drugs in a Mimetic Tissue Model Using Nano-DESI on a Triple Quadrupole Mass Spectrometer

inferred← citeshttps://doi.org/10.1021/jasms.5c00424openalex-snapshot

Complementary UV-MALDI and IR-MALDESI Imaging Expand Metabolomic Coverage in the 6-OHDA Rat Model of Parkinson’s Disease

inferred← citeshttps://doi.org/10.1021/jasms.6c00161openalex-snapshot

MALDI MSI Workflow for Pharmaceutical Tablets: Toward a Reproducible Strategy for High-Resolution Imaging

inferred← citeshttps://doi.org/10.1038/nprot.2016.081openalex-snapshot

High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue

inferred← citeshttps://doi.org/10.1038/s41380-021-01267-yopenalex-snapshot

Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood–brain barrier

inferred← citeshttps://doi.org/10.1038/s41386-019-0397-5openalex-snapshot

Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition

inferred← citeshttps://doi.org/10.1038/s41467-025-64604-7openalex-snapshot

Subcellular mass spectrometry imaging of lipids and nucleotides using transmission geometry ambient laser desorption and plasma ionisation

inferred← citeshttps://doi.org/10.1038/s41524-020-00357-9openalex-snapshot

Toward nanoscale molecular mass spectrometry imaging via physically constrained machine learning on co-registered multimodal data

inferred← citeshttps://doi.org/10.1038/s41598-017-05216-0openalex-snapshot

MALDI-TOF MS as a Novel Tool for the Estimation of Postmortem Interval in Liver Tissue Samples

inferred← citeshttps://doi.org/10.1038/s41598-017-06583-4openalex-snapshot

Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis

inferred← citeshttps://doi.org/10.1038/s41598-017-13025-8openalex-snapshot

Evaluation of the heterogeneous tissue distribution of erlotinib in lung cancer using matrix-assisted laser desorption ionization mass spectrometry imaging

inferred← citeshttps://doi.org/10.1038/s41598-017-17211-6openalex-snapshot

MALDI mass spectrometry imaging of erlotinib administered in combination with bevacizumab in xenograft mice bearing B901L, EGFR-mutated NSCLC cells

inferred← citeshttps://doi.org/10.1038/s41598-020-72665-5openalex-snapshot

Visualization of the distribution of nanoparticle-formulated AZD2811 in mouse tumor model using matrix-assisted laser desorption ionization mass spectrometry imaging

inferred← citeshttps://doi.org/10.1038/s41598-023-38699-1openalex-snapshot

DISC-3D: dual-hydrogel system enhances optical imaging and enables correlative mass spectrometry imaging of invading multicellular tumor spheroids

inferred← citeshttps://doi.org/10.1038/s43586-026-00492-5openalex-snapshot

Matrix-assisted laser desorption/ionization imaging mass spectrometry

inferred← citeshttps://doi.org/10.1038/srep23749openalex-snapshot

Visualizing spatial distribution of alectinib in murine brain using quantitative mass spectrometry imaging

inferred← citeshttps://doi.org/10.1038/srep38507openalex-snapshot

Chemical Imaging of Platinum-Based Drugs and their Metabolites

inferred← citeshttps://doi.org/10.1038/srep39284openalex-snapshot

Heterogeneity of paclitaxel distribution in different tumor models assessed by MALDI mass spectrometry imaging

inferred← citeshttps://doi.org/10.1039/bk9781837670338-00234openalex-snapshot

Mass Spectrometry Imaging in Microbiology

inferred← citeshttps://doi.org/10.1039/c5an00990aopenalex-snapshot

MALDI mass spectrometric imaging meets “omics”: recent advances in the fruitful marriage

inferred← citeshttps://doi.org/10.1039/c5an02620bopenalex-snapshot

Quantitative mass spectrometry imaging of small-molecule neurotransmitters in rat brain tissue sections using nanospray desorption electrospray ionization

inferred← citeshttps://doi.org/10.1039/c6an00665eopenalex-snapshot

Correlating microscopy techniques and ToF-SIMS analysis of fully grown mammalian oocytes

inferred← citeshttps://doi.org/10.1039/c6an02721kopenalex-snapshot

Molecular imaging of small molecule drugs in animal tissues using laser desorption postionization mass spectrometry

inferred← citeshttps://doi.org/10.1039/c6ay00096gopenalex-snapshot

Characterization of firearm discharge residues recovered from skin swabs using sub-micrometric mass spectrometry imaging

inferred← citeshttps://doi.org/10.1039/c6ay02753aopenalex-snapshot

Matrix-enhanced nanostructure initiator mass spectrometry (ME-NIMS) for small molecule detection and imaging

inferred← citeshttps://doi.org/10.1039/c6cc02387hopenalex-snapshot

Maleic anhydride proton sponge as a novel MALDI matrix for the visualization of small molecules (<250 m/z) in brain tumors by routine MALDI ToF imaging mass spectrometry

inferred← citeshttps://doi.org/10.1039/c7an00565bopenalex-snapshot

Mass spectrometry imaging for clinical research – latest developments, applications, and current limitations

inferred← citeshttps://doi.org/10.1039/c7an00901aopenalex-snapshot

A pneumatically assisted nanospray desorption electrospray ionization source for increased solvent versatility and enhanced metabolite detection from tissue

inferred← citeshttps://doi.org/10.1039/d0an02333gopenalex-snapshot

Multimodal imaging of drug and excipients in rat lungs following an inhaled administration of controlled-release drug laden PLGA microparticles

inferred← citeshttps://doi.org/10.1039/d2an00355dopenalex-snapshot

Imaging mass spectrometry differentiates the effects of doxorubicin formulations on non-targeted tissues

inferred← citeshttps://doi.org/10.1039/d3ay01267kopenalex-snapshot

Recent developments and applications of ambient mass spectrometry imaging in pharmaceutical research: an overview

inferred← citeshttps://doi.org/10.1039/d4cc02475copenalex-snapshot

Hydrazide-based reactive matrices for the sensitive detection of aldehydes and ketones by MALDI mass spectrometry imaging

inferred← citeshttps://doi.org/10.1039/d5ja00495kopenalex-snapshot

Development of a plasma injection probe for deep tissue drug analysis

inferred← citeshttps://doi.org/10.1080/00498254.2022.2119900openalex-snapshot

Potential application of mass spectrometry imaging in pharmacokinetic studies

inferred← citeshttps://doi.org/10.1080/05704928.2016.1207659openalex-snapshot

MALDI-MS of drugs: Profiling, imaging, and steps towards quantitative analysis

inferred← citeshttps://doi.org/10.1080/17425247.2018.1541084openalex-snapshot

Delivery of amitriptyline by intravenous and intraperitoneal administration compared in the same animal by whole-body mass spectrometry imaging of a stable isotope labelled drug substance in mice

inferred← citeshttps://doi.org/10.1093/gigascience/giad021openalex-snapshot

Delineating regions of interest for mass spectrometry imaging by multimodally corroborated spatial segmentation

inferred← citeshttps://doi.org/10.1111/bph.14067openalex-snapshot

Heterogeneous distribution of alectinib in neuroblastoma xenografts revealed by matrix‐assisted laser desorption ionization mass spectrometry imaging: a pilot study

inferred← citeshttps://doi.org/10.1111/jnc.14559openalex-snapshot

Molecular imaging mass spectrometry for probing protein dynamics in neurodegenerative disease pathology

inferred← citeshttps://doi.org/10.1111/jnc.70315openalex-snapshot

Considerations for Spatial Omics, Metabolite Analyses, and Tissue‐Harvesting Artifacts

inferred← citeshttps://doi.org/10.11606/t.60.2017.tde-03052017-160135openalex-snapshot

Disposição cinética, metabolismo e permeabilidade intestinal in vitro do alcaloide Govaniadina

inferred← citeshttps://doi.org/10.1172/jci.insight.206951openalex-snapshot

Spatial multiomics in biomedical research: advances beyond transcriptomics

inferred← citeshttps://doi.org/10.1177/1087057115623740openalex-snapshot

Exemplifying the Screening Power of Mass Spectrometry Imaging over Label-Based Technologies for Simultaneous Monitoring of Drug and Metabolite Distributions in Tissue Sections

inferred← citeshttps://doi.org/10.1186/s12859-022-04671-5openalex-snapshot

Mass recalibration for desorption electrospray ionization mass spectrometry imaging using endogenous reference ions

inferred← citeshttps://doi.org/10.1186/s12931-022-02026-5openalex-snapshot

Mass spectrometry detection of inhaled drug in distal fibrotic lung

inferred← citeshttps://doi.org/10.1186/s13550-017-0281-4openalex-snapshot

High-throughput high-volume nuclear imaging for preclinical in vivo compound screening§

inferred← citeshttps://doi.org/10.1186/s40478-026-02361-4openalex-snapshot

Multimodal molecular mapping of the vasculature in human cortex reveals lipid markers of cerebral amyloid angiopathy

inferred← citeshttps://doi.org/10.1186/s40580-018-0157-yopenalex-snapshot

Biological tissue sample preparation for time-of-flight secondary ion mass spectrometry (ToF–SIMS) imaging

inferred← citeshttps://doi.org/10.1201/9781315116372-2openalex-snapshot

Quantitative Mass Spectrometry Imaging of Molecules in Biological Systems

inferred← citeshttps://doi.org/10.1369/0022155418815860openalex-snapshot

Defining Changes in the Spatial Distribution and Composition of Brain Lipids in the Shiverer and Cuprizone Mouse Models of Myelin Disease

inferred← citeshttps://doi.org/10.15212/amm-2022-0046openalex-snapshot

Mass spectrometry imaging advances and application in pharmaceutical research

inferred← citeshttps://doi.org/10.18494/sam.2019.2371openalex-snapshot

Detection and Visualization of Food-derived Polyphenols by Matrix-assisted Laser Desorption/Ionization Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.18632/oncotarget.24928openalex-snapshot

Distribution of erlotinib in rash and normal skin in cancer patients receiving erlotinib visualized by matrix assisted laser desorption/ionization mass spectrometry imaging

inferred← citeshttps://doi.org/10.21203/rs.3.rs-1432835/v1openalex-snapshot

X-dimensional Mass Spectrometry Imaging Discovers Spatially Resolved Metabolic Response

inferred← citeshttps://doi.org/10.21203/rs.3.rs-515610/v1openalex-snapshot

Mass Spectrometry Detection of Inhaled Drug in Distal Fibrotic Lung

inferred← citeshttps://doi.org/10.2174/0115734110401212250806053745openalex-snapshot

Advancements in Mass Spectrometry Imaging for Cancer Research: From Tumor Profiling to Personalized Medicine

inferred← citeshttps://doi.org/10.31390/gradschool_dissertations.5103openalex-snapshot

Electrification Ionization: Fundamentals and Applications

inferred← citeshttps://doi.org/10.3389/fchem.2025.1523712openalex-snapshot

A laboratory-friendly protocol for freeze-drying sample preparation in ToF-SIMS single-cell imaging

inferred← citeshttps://doi.org/10.3389/fnagi.2023.1150512openalex-snapshot

Untangling Alzheimer’s disease with spatial multi-omics: a brief review

inferred← citeshttps://doi.org/10.3389/fphys.2022.837773openalex-snapshot

Uncovering Molecular Heterogeneity in the Kidney With Spatially Targeted Mass Spectrometry

inferred← citeshttps://doi.org/10.3389/fpls.2018.01348openalex-snapshot

Light-Dependent Changes in the Spatial Localization of Metabolites in Solenostemon scutellarioides (Coleus Henna) Visualized by Matrix-Free Atmospheric Pressure Electrospray Laser Desorption Ionization Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.3390/ijms18122588openalex-snapshot

Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry Imaging in the Study of Gastric Cancer: A Mini Review

inferred← citeshttps://doi.org/10.3390/ph15101180openalex-snapshot

Evaluation of Quantitative Platforms for Single Target Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.3390/pharmaceutics12010020openalex-snapshot

ABC Transporters at the Blood–Brain Interfaces, Their Study Models, and Drug Delivery Implications in Gliomas

inferred← citeshttps://doi.org/10.4155/bio.15.186openalex-snapshot

An Introduction to MS Imaging in Drug Discovery and Development

inferred← citeshttps://doi.org/10.47749/t/unicamp.2018.1014621openalex-snapshot

Estudo comparativo entre ativos farmacêuticos e espécies relacionadas utilizando imageamento obtido por espectrometria de massas-MALDI

inferred← citeshttps://doi.org/10.5702/massspec.24-017openalex-snapshot

Quantitative Analysis in MALDI-MSI

inferred← citeshttps://doi.org/10.5702/massspec.s19-26openalex-snapshot

Ambient Ionization Mass Spectrometry Imaging by Desorption Electrospray Ionization (DESI)

inferred← citeshttps://doi.org/10.5702/massspectrometry.a0175openalex-snapshot

Recent Applications of Artificial Intelligence and Related Technical Challenges in MALDI MS and MALDI-MSI: A Mini Review

inferred← citeshttps://doi.org/10.6060/ivkkt.20206309.6230openalex-snapshot

SYNTHESIS AND MASS SPECTROMETRIC CHARACTERISTICS OF 1-(AMINOARYL)BENZIMIDAZOLES

inferred← citeshttps://doi.org/10.6084/m9.figshare.19607644openalex-snapshot

Additional file 1 of Mass recalibration for desorption electrospray ionization mass spectrometry imaging using endogenous reference ions

inferred← citeshttps://doi.org/10.6084/m9.figshare.19753155openalex-snapshot

Additional file 1 of Mass spectrometry detection of inhaled drug in distal fibrotic lung

inferred← citeshttps://doi.org/10.70675/702a81e5z56c9z4beazbfa4z97d920c69c55openalex-snapshot

Utilisation de l'imagerie par spectrométrie de masse et son optimisation au cours du processus de développement de médicaments

inferred← citeshttps://doi.org/10.7150/ijbs.41395openalex-snapshot

Quantitative determination of niraparib and olaparib tumor distribution by mass spectrometry imaging

inferred← citeshttps://doi.org/10.7150/thno.41763openalex-snapshot

Evaluation of the tumor-targeting efficiency and intratumor heterogeneity of anticancer drugs using quantitative mass spectrometry imaging

inferred← citeshttps://doi.org/10.7190/shu-thesis-00406openalex-snapshot

Imaging Three-Dimensional Cell-Culture Models for Pre-Clinical Biopharmaceutical Testing

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