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Characterization of Antibody Charge Heterogeneity Resolved by Preparative Immobilized pH Gradients
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/bit.21260openalex-snapshot
Determination of the origin of the N‐terminal pyro‐glutamate variation in monoclonal antibodies using model peptides
inferredcites →https://doi.org/10.1002/elps.11501501141openalex-snapshot
Multifunctional apparatus for electrokinetic processing of proteins
inferredcites →https://doi.org/10.1002/elps.1150190703openalex-snapshot
Recycling isoelectric focusing and isotachophoresis
inferredcites →https://doi.org/10.1002/elps.200305722openalex-snapshot
Immobilized pH gradients as a first dimension in shotgun proteomics and analysis of the accuracy of pI predictability of peptides
inferredcites →https://doi.org/10.1002/elps.200305779openalex-snapshot
Narrow‐band fractionation of proteins from whole cell lysates using isoelectric membrane focusing and nonporous reversed‐phase separations
inferredcites →https://doi.org/10.1002/elps.200305832openalex-snapshot
Preparative isoelectric focusing of proteins using binary buffers in a vortex‐stabilized, free‐flow apparatus
inferredcites →https://doi.org/10.1002/elps.200700584openalex-snapshot
Capillary electrophoresis of proteins 2005–2007
inferredcites →https://doi.org/10.1002/elps.200780845openalex-snapshot
Protein separation using preparative‐scale dynamic field gradient focusing
inferredcites →https://doi.org/10.1002/elps.200800157openalex-snapshot
Application of imaging capillary IEF for characterization and quantitative analysis of recombinant protein charge heterogeneity
inferredcites →https://doi.org/10.1002/elps.200800740openalex-snapshot
Development and characterization of cIEF‐MALDI‐TOF MS for protein analysis
inferredcites →https://doi.org/10.1002/jps.21655openalex-snapshot
Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain
inferredcites →https://doi.org/10.1002/pmic.200300472openalex-snapshot
Prefractionation techniques in proteome analysis
inferredcites →https://doi.org/10.1002/pmic.200600587openalex-snapshot
Establishing a liquid‐phase IEF in combination with 2‐DE for the analysis of Leishmania proteins
inferredcites →https://doi.org/10.1002/pmic.200800351openalex-snapshot
Peptide separation with immobilized pI strips is an attractive alternative to in‐gel protein digestion for proteome analysis
inferredcites →https://doi.org/10.1016/0003-2697(89)90136-xopenalex-snapshot
Isoelectric points of proteins: Theoretical determination
inferredcites →https://doi.org/10.1016/0021-9673(92)85530-7openalex-snapshot
Recycling isoelectric focusing: use of simple buffers
inferredcites →https://doi.org/10.1016/0021-9673(94)01255-dopenalex-snapshot
Processing of C-terminal lysine and arginine residues of proteins isolated from mammalian cell culture
inferredcites →https://doi.org/10.1016/0021-9673(96)00437-2openalex-snapshot
Capillary isoelectric focusing and sodium dodecyl sulfate-capillary gel electrophoresis of recombinant humanized monoclonal antibody HER2
inferredcites →https://doi.org/10.1016/j.ab.2005.10.003openalex-snapshot
Analysis of recombinant monoclonal antibody isoforms by electrospray ionization mass spectrometry as a strategy for streamlining characterization of recombinant monoclonal antibody charge heterogeneity
inferredcites →https://doi.org/10.1016/j.ab.2007.09.027openalex-snapshot
A study in glycation of a therapeutic recombinant humanized monoclonal antibody: Where it is, how it got there, and how it affects charge-based behavior
inferredcites →https://doi.org/10.1016/j.ab.2010.01.008openalex-snapshot
Analysis of monoclonal antibody product heterogeneity resulting from alternate cleavage sites of signal peptide
inferredcites →https://doi.org/10.1016/j.chroma.2005.10.053openalex-snapshot
Reversed-phase liquid chromatography/mass spectrometry analysis of reduced monoclonal antibodies in pharmaceutics
inferredcites →https://doi.org/10.1016/j.chroma.2007.11.088openalex-snapshot
Reversed-phase liquid chromatography–mass spectrometry of site-specific chemical modifications in intact immunoglobulin molecules and their fragments
inferredcites →https://doi.org/10.1016/j.chroma.2008.05.057openalex-snapshot
Recent developments in capillary isoelectric focusing
inferredcites →https://doi.org/10.1016/j.imlet.2007.05.002openalex-snapshot
Identification of an alternative signal peptide cleavage site of mouse monoclonal antibodies by mass spectrometry
inferredcites →https://doi.org/10.1016/j.jasms.2007.12.006openalex-snapshot
Molecular mass analysis of antibodies by on-line SEC-MS
inferredcites →https://doi.org/10.1016/j.jchromb.2006.09.026openalex-snapshot
Downstream processing of monoclonal antibodies—Application of platform approaches
inferredcites →https://doi.org/10.1016/s0021-9673(01)00662-8openalex-snapshot
Validatibility of a capillary isoelectric focusing method for impurity quantitation
inferredcites →https://doi.org/10.1016/s0021-9673(01)89684-9openalex-snapshot
Preparative protein purification in a multi-compartment electrolyser with immobiline membranes
inferredcites →https://doi.org/10.1016/s0021-9673(02)01525-xopenalex-snapshot
Design of a new, twelve-channel electrophoretic apparatus based on the Gradiflow technology
inferredcites →https://doi.org/10.1016/s0021-9673(97)01134-5openalex-snapshot
Validation of a capillary isoelectric focusing method for the recombinant monoclonal antibody C2B8
inferredcites →https://doi.org/10.1016/s0021-9673(99)00127-2openalex-snapshot
Characterization of the isoforms of PIXY321, a granulocyte-macrophage-colony stimulating factor–interleukin-3 fusion protein, separated by preparative isoelectric focusing on immobilized pH gradients
inferredcites →https://doi.org/10.1016/s0731-7085(02)00479-xopenalex-snapshot
Analysis of isoaspartate in a recombinant monoclonal antibody and its charge isoforms
inferredcites →https://doi.org/10.1016/s0731-7085(97)00178-7openalex-snapshot
Validation of an HPLC method for the analysis of the charge heterogeneity of the recombinant monoclonal antibody IDEC-C2B8 after papain digestion
inferredcites →https://doi.org/10.1021/ac0482256openalex-snapshot
Evaluating Preparative Isoelectric Focusing of Complex Peptide Mixtures for Tandem Mass Spectrometry-Based Proteomics: A Case Study in Profiling Chromatin-Enriched Subcellular Fractions inSaccharomycescerevisiae
inferredcites →https://doi.org/10.1021/ac049717lopenalex-snapshot
A Proteome Strategy for Fractionating Proteins and Peptides Using Continuous Free-Flow Electrophoresis Coupled Off-Line to Reversed-Phase High-Performance Liquid Chromatography
inferredcites →https://doi.org/10.1021/ac071147copenalex-snapshot
Intact Protein Profiling of Chlorobium tepidum by Capillary Isoelectric Focusing, Reversed-Phase Liquid Chromatography, and Mass Spectrometry
inferredcites →https://doi.org/10.1074/mcp.m800206-mcp200openalex-snapshot
Proteomics Analysis of the Excretory/Secretory Component of the Blood-feeding Stage of the Hookworm, Ancylostoma caninum
inferredcites →https://doi.org/10.1074/mcp.t600037-mcp200openalex-snapshot
Efficient Fractionation and Improved Protein Identification by Peptide OFFGEL Electrophoresis
inferredcites →https://doi.org/10.1093/glycob/cwn116openalex-snapshot
O-Fucosylation of an antibody light chain: Characterization of a modification occurring on an IgG1 molecule
inferredcites →https://doi.org/10.1093/humrep/dei411openalex-snapshot
Pituitary–ovarian axis during lactational amenorrhoea. II. Longitudinal assessment of serum FSH polymorphism before and after recovery of menstrual cycles
inferredcites →https://doi.org/10.1186/1477-5956-6-27openalex-snapshot
Improved proteome coverage by using iTRAQ labelling and peptide OFFGEL fractionation
inferredcites →https://doi.org/10.2174/138920108786786402openalex-snapshot
Heterogeneity of Monoclonal Antibodies Revealed by Charge-Sensitive Methods
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4812100openalex-extracted
An Integrated Protocol Based on Workflows of Imaged Capillary Isoelectric Focusing (Icief) for In-Depth Protein Heterogenous Characterization: High-Efficient Fractionation and Online Mass Spectrometry Detection
inferred← citeshttps://doi.org/10.1002/9780470571224.pse509openalex-snapshot
Analytical Characterization of Proteins and Peptides
inferred← citeshttps://doi.org/10.1002/bit.27776openalex-snapshot
Antibody capture process based on magnetic beads from very high cell density suspension
inferred← citeshttps://doi.org/10.1002/btpr.2327openalex-snapshot
Impact of cell culture on recombinant monoclonal antibody product heterogeneity
inferred← citeshttps://doi.org/10.1002/elps.201300372openalex-snapshot
Applications of capillary electrophoresis in characterizing recombinant protein therapeutics
inferred← citeshttps://doi.org/10.1002/elps.201500219openalex-snapshot
Characterization of acidic and basic variants of IgG1 therapeutic monoclonal antibodies based on non‐denaturing IEF fractionation
inferred← citeshttps://doi.org/10.1002/elps.201700445openalex-snapshot
Microscale isolation of native forms of lysozyme from chicken egg white by gel isoelectric focusing
inferred← citeshttps://doi.org/10.1002/elps.202100348openalex-snapshot
Global intercompany assessment of ICIEF platform comparability for the characterization of therapeutic proteins
inferred← citeshttps://doi.org/10.1002/jps.22504openalex-snapshot
Characterization of Site-Specific Glycation During Process Development of a Human Therapeutic Monoclonal Antibody
inferred← citeshttps://doi.org/10.1002/jssc.201200633openalex-snapshot
Robustness of i CIEF methodology for the analysis of monoclonal antibodies: An interlaboratory study
inferred← citeshttps://doi.org/10.1002/jssc.201301041openalex-snapshot
Peptide prefractionation is essential for proteomic approaches employing multiple‐reaction monitoring of fruit proteomic research
inferred← citeshttps://doi.org/10.1007/978-3-030-31415-6_1openalex-snapshot
Chapter 1: Monoclonal Antibodies: Structure, Physicochemical Stability, and Protein Engineering
inferred← citeshttps://doi.org/10.1007/978-3-642-35043-6_7openalex-snapshot
Capillary Isoelectric Focusing
inferred← citeshttps://doi.org/10.1007/s00216-015-8618-1openalex-snapshot
An optimized approach to the rapid assessment and detection of sequence variants in recombinant protein products
inferred← citeshttps://doi.org/10.1007/s10337-011-2017-3openalex-snapshot
Intercompany Study to Evaluate the Robustness of Capillary Isoelectric Focusing Technology for the Analysis of Monoclonal Antibodies
inferred← citeshttps://doi.org/10.1007/s10337-022-04215-2openalex-snapshot
Beyond PTMs: Novel Charge Variants Discovered in icIEF Profiling of PEGylated Proteins
inferred← citeshttps://doi.org/10.1016/b978-0-08-100623-8.00047-5openalex-snapshot
Analytical Methods
inferred← citeshttps://doi.org/10.1016/b978-0-12-809375-7.00021-6openalex-snapshot
Biopharmaceutical Applications of Capillary Electromigration Methods
inferred← citeshttps://doi.org/10.1016/b978-0-12-822318-5.00008-9openalex-snapshot
Separation techniques for characterization and quantification of monoclonal antibody purity
inferred← citeshttps://doi.org/10.1016/j.ab.2013.01.017openalex-snapshot
Method to convert N-terminal glutamine to pyroglutamate for characterization of recombinant monoclonal antibodies
inferred← citeshttps://doi.org/10.1016/j.ab.2016.12.017openalex-snapshot
Characterization of charge variants of a monoclonal antibody using weak anion exchange chromatography at subunit levels
inferred← citeshttps://doi.org/10.1016/j.ab.2018.10.002openalex-snapshot
Characterization of recombinant monoclonal antibody charge variants using WCX chromatography, icIEF and LC-MS/MS
inferred← citeshttps://doi.org/10.1016/j.ab.2022.114961openalex-snapshot
Cutting-edge mass spectrometry strategy based on imaged capillary isoelectric focusing (icIEF) technology for characterizing charge heterogeneity of monoclonal antibody
inferred← citeshttps://doi.org/10.1016/j.ab.2025.115825openalex-snapshot
Advancing protein heterogeneity analysis: Nano-flow pressure mobilization for precise icIEF fractionation and online MS detection
inferred← citeshttps://doi.org/10.1016/j.aca.2018.10.036openalex-snapshot
A porous layer open-tubular capillary column with immobilized pH gradient (PLOT-IPG) for isoelectric focusing of amino acids and proteins
inferred← citeshttps://doi.org/10.1016/j.aca.2020.12.064openalex-snapshot
Fractionated charge variants of biosimilars: A review of separation methods, structural and functional analysis
inferred← citeshttps://doi.org/10.1016/j.biologicals.2016.12.006openalex-snapshot
Charge variant analysis of proposed biosimilar to Trastuzumab
inferred← citeshttps://doi.org/10.1016/j.chroma.2013.10.028openalex-snapshot
Highly linear pH gradients for analyzing monoclonal antibody charge heterogeneity in the alkaline range
inferred← citeshttps://doi.org/10.1016/j.copbio.2014.06.012openalex-snapshot
Therapeutic monoclonal antibodies and consistent ends: terminal heterogeneity, detection, and impact on quality
inferred← citeshttps://doi.org/10.1016/j.greeac.2024.100122openalex-snapshot
Retracted:An integrated protocol based on workflows of imaged capillary isoelectric focusing (icIEF) for in-depth protein heterogenous characterization: High-efficient fractionation and online mass spectrometry detection
inferred← citeshttps://doi.org/10.1016/j.greeac.2025.100204openalex-snapshot
An integrated protocol based on workflows of imaged capillary isoelectric focusing (icIEF) for in-depth protein heterogenous characterization: High-efficient fractionation and online mass spectrometry detection
inferred← citeshttps://doi.org/10.1016/j.jchromb.2011.08.015openalex-snapshot
Detection and identification of a serine to arginine sequence variant in a therapeutic monoclonal antibody
inferred← citeshttps://doi.org/10.1016/j.jchromb.2016.05.028openalex-snapshot
Cutting-edge capillary electrophoresis characterization of monoclonal antibodies and related products
inferred← citeshttps://doi.org/10.1016/j.jchromb.2017.11.043openalex-snapshot
Correlating charge heterogeneity data generated by agarose gel isoelectric focusing and ion exchange chromatography methods
inferred← citeshttps://doi.org/10.1016/j.jchromb.2017.12.003openalex-snapshot
Rapid preparative separation of monoclonal antibody charge variants using laterally-fed membrane chromatography
inferred← citeshttps://doi.org/10.1016/j.jchromb.2018.03.049openalex-snapshot
Characterization of recombinant monoclonal antibody variants detected by hydrophobic interaction chromatography and imaged capillary isoelectric focusing electrophoresis
inferred← citeshttps://doi.org/10.1016/j.jpba.2020.113217openalex-snapshot
Characterization of the acidic species of a monoclonal antibody using free flow electrophoresis fractionation and mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.jpba.2022.115178openalex-snapshot
Imaged Capillary Isoelectric Focusing (iCIEF) Tandem High Resolution Mass Spectrometry for Charged Heterogeneity of Protein Drugs in Biopharmaceutical Discovery
inferred← citeshttps://doi.org/10.1016/j.jpba.2023.115494openalex-snapshot
Exploring proteoforms of the IgG2 monoclonal antibody panitumumab using microchip capillary electrophoresis-mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.talanta.2015.12.070openalex-snapshot
Stability and effectiveness of linear polyacrylamide capillary coating to suppress EOF in acidic media in the presence of surfactants, ionic liquids and organic modifiers
inferred← citeshttps://doi.org/10.1016/j.trac.2025.118212openalex-snapshot
Recent developments of imaged capillary isoelectric focusing technology for in-depth biopharmaceutical characterization
inferred← citeshttps://doi.org/10.1021/ac201741wopenalex-snapshot
High Throughput Profiling of Charge Heterogeneity in Antibodies by Microchip Electrophoresis
inferred← citeshttps://doi.org/10.1021/ac3008847openalex-snapshot
Charge Heterogeneity of Monoclonal Antibodies by Multiplexed Imaged Capillary Isoelectric Focusing Immunoassay with Chemiluminescence Detection
inferred← citeshttps://doi.org/10.1021/ac3032355openalex-snapshot
Characterization of Therapeutic Antibodies and Related Products
inferred← citeshttps://doi.org/10.1021/ac502372ropenalex-snapshot
Semiautomated pH Gradient Ion-Exchange Chromatography of Monoclonal Antibody Charge Variants
inferred← citeshttps://doi.org/10.1021/ac504427kopenalex-snapshot
Characterization of the N-Terminal Heterogeneities of Monoclonal Antibodies Using In-Gel Charge Derivatization of α-Amines and LC-MS/MS
inferred← citeshttps://doi.org/10.1021/acs.analchem.5b01452openalex-snapshot
Characterization of Recombinant Monoclonal Antibody Charge Variants Using OFFGEL Fractionation, Weak Anion Exchange Chromatography, and Mass Spectrometry
inferred← citeshttps://doi.org/10.1021/acs.analchem.5b02385openalex-snapshot
Characterization of the Acidic Species of a Monoclonal Antibody Using Weak Cation Exchange Chromatography and LC-MS
inferred← citeshttps://doi.org/10.1021/acs.analchem.5b03946openalex-snapshot
Isolation and Characterization of Monoclonal Antibody Charge Variants by Free Flow Isoelectric Focusing
inferred← citeshttps://doi.org/10.1021/bk-2014-1176.ch003openalex-snapshot
Heterogeneity of IgGs: Role of Production, Processing, and Storage on Structure and Function
inferred← citeshttps://doi.org/10.1021/bk-2015-1202.ch009openalex-snapshot
Monoclonal Antibody Analysis Using Microfluidic Technologies
inferred← citeshttps://doi.org/10.1039/d2ay01670bopenalex-snapshot
Fractionation and online mass spectrometry based on imaged capillary isoelectric focusing (icIEF) for characterizing charge heterogeneity of therapeutic antibody
inferred← citeshttps://doi.org/10.1080/10826076.2011.619035openalex-snapshot
IMPROVED ION-EXCHANGED HPLC METHOD IN mAb USING pH GRADIENT AND ITS COMPARISON WITH cIEF
inferred← citeshttps://doi.org/10.1080/19420862.2018.1553476openalex-snapshot
Structure, heterogeneity and developability assessment of therapeutic antibodies
inferred← citeshttps://doi.org/10.1080/19420862.2020.1763762openalex-snapshot
Hyphenation of strong cation exchange chromatography to native mass spectrometry for high throughput online characterization of charge heterogeneity of therapeutic monoclonal antibodies
inferred← citeshttps://doi.org/10.1080/19420862.2025.2537116openalex-snapshot
Ion-exchange chromatography, capillary isoelectric focusing, and capillary zone electrophoresis coupled to mass spectrometry for charge variant analysis of monoclonal antibodies
inferred← citeshttps://doi.org/10.1109/tnb.2017.2763779openalex-snapshot
Two-Dimensional Isoelectric Focusing OFFGEL, Micro-Fluidic Lab-on-Chip Electrophoresis and FTIR for Assessment of Long-Term Stability of rhG-CSF Formulation
inferred← citeshttps://doi.org/10.26717/bjstr.2019.20.003395openalex-snapshot
Charge Variants Analysis of Recombinant Monoclonal Antibodies
inferred← citeshttps://doi.org/10.3390/antib11040073openalex-snapshot
Risk-Based Control Strategies of Recombinant Monoclonal Antibody Charge Variants
inferred← citeshttps://doi.org/10.3390/antib8010018openalex-snapshot
Macro- and Micro-Heterogeneity of Natural and Recombinant IgG Antibodies
inferred← citeshttps://doi.org/10.4161/mabs.3.6.18090openalex-snapshot
An innovative approach for the characterization of the isoforms of a monoclonal antibody product
inferred← citeshttps://doi.org/10.4161/mabs.36222openalex-snapshot
Rapid identification of an antibody DNA construct rearrangement sequence variant by mass spectrometry
inferred← citeshttps://doi.org/10.70675/25b4d051z172bz4cdez9583ze25fd7639e1fopenalex-snapshot
Mise en place d’une approche protéomique en vue d’une application au diagnostic d’infections parasitaires congénitales
inferred← citeshttps://doi.org/10.70675/706cdd43zdd95z4f0dz8b0cz49421d515990openalex-snapshot
Caractérisation d’anticorps monoclonaux à différents niveaux à l’aide d’un couplage électrophorèse capillaire – spectrométrie de masse
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