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Development of a Prodrug of Camptothecin for Enhanced Treatment of Glioblastoma Multiforme
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/jama.2013.280319openalex-snapshot
Glioblastoma and Other Malignant Gliomas
inferredcites →https://doi.org/10.1002/ana.22425openalex-snapshot
Current concepts and management of glioblastoma
inferredcites →https://doi.org/10.1002/cam4.219openalex-snapshot
U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cells
inferredcites →https://doi.org/10.1002/lsm.22359openalex-snapshot
Fluorescence guided resection and glioblastoma in 2015: A review
inferredcites →https://doi.org/10.1007/s00280-005-0169-2openalex-snapshot
The cytotoxic and genotoxic potential of 5-aminolevulinic acid on lymphocytes: a comet assay study
inferredcites →https://doi.org/10.1007/s00401-016-1545-1openalex-snapshot
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
inferredcites →https://doi.org/10.1007/s00701-016-3014-yopenalex-snapshot
Evaluation of the risk of liver damage from the use of 5-aminolevulinic acid for intra-operative identification and resection in patients with malignant gliomas
inferredcites →https://doi.org/10.1007/s10014-006-0195-8openalex-snapshot
Pathological and clinical features of cystic and noncystic glioblastomas
inferredcites →https://doi.org/10.1007/s11060-006-9325-8openalex-snapshot
Massive apoptotic cell death of human glioma cells via a mitochondrial pathway following 5-aminolevulinic acid-mediated photodynamic therapy
inferredcites →https://doi.org/10.1007/s11060-011-0714-2openalex-snapshot
Genomic profiling of glioblastoma: convergence of fundamental biologic tenets and novel insights
inferredcites →https://doi.org/10.1016/j.bmc.2004.04.023openalex-snapshot
Synthesis and antitumor activity of 20-O-linked nitrogen-based camptothecin ester derivatives
inferredcites →https://doi.org/10.1016/j.det.2006.09.005openalex-snapshot
Aminolevulinic Acid Photodynamic Therapy for Skin Cancers
inferredcites →https://doi.org/10.1016/j.drup.2015.02.002openalex-snapshot
Overcoming the blood–brain tumor barrier for effective glioblastoma treatment
inferredcites →https://doi.org/10.1016/j.ijpharm.2017.02.016openalex-snapshot
Non-viral vectors based on magnetoplexes, lipoplexes and polyplexes for VEGF gene delivery into central nervous system cells
inferredcites →https://doi.org/10.1016/j.ijpharm.2020.119283openalex-snapshot
Glioblastoma chemotherapeutic agents used in the clinical setting and in clinical trials: Nanomedicine approaches to improve their efficacy
inferredcites →https://doi.org/10.1016/j.jconrel.2011.06.039openalex-snapshot
Surface-modified silica nanoparticles for tumor-targeted delivery of camptothecin and its biological evaluation
inferredcites →https://doi.org/10.1016/j.jconrel.2013.07.022openalex-snapshot
Prodrug and nanomedicine approaches for the delivery of the camptothecin analogue SN38
inferredcites →https://doi.org/10.1016/j.jconrel.2016.12.023openalex-snapshot
Safe approaches for camptothecin delivery: Structural analogues and nanomedicines
inferredcites →https://doi.org/10.1016/j.jpba.2004.04.006openalex-snapshot
Degradation of camptothecin-20(S)-glycinate ester prodrug under physiological conditions
inferredcites →https://doi.org/10.1016/j.mam.2017.01.009openalex-snapshot
Multidrug resistance in glioblastoma stem-like cells: Role of the hypoxic microenvironment and adenosine signaling
inferredcites →https://doi.org/10.1016/j.mehy.2019.109314openalex-snapshot
Hypothesis: Metabolic targeting of 5-aminolevulinate synthase by tryptophan and inhibitors of heme utilisation by tryptophan 2,3-dioxygenase as potential therapies of acute hepatic porphyrias
inferredcites →https://doi.org/10.1016/j.mpsur.2012.01.002openalex-snapshot
Pathology of tumours of the central nervous system
inferredcites →https://doi.org/10.1016/j.pdpdt.2020.101714openalex-snapshot
In vitro evaluation of cytotoxic properties of 5-Aminolevulinic acid (5-ALA) on bladder cancer cells
inferredcites →https://doi.org/10.1016/s0361-9230(99)00072-6openalex-snapshot
The glial scar and central nervous system repair
inferredcites →https://doi.org/10.1016/s0968-0896(98)00005-4openalex-snapshot
Camptothecin-20-PEG ester transport forms: the effect of spacer groups on antitumor activity
inferredcites →https://doi.org/10.1021/am5022864openalex-snapshot
Tunable Temperature-Responsive Supramolecular Hydrogels Formed by Prodrugs As a Codelivery System
inferredcites →https://doi.org/10.1021/bc010027nopenalex-snapshot
Synthesis and Biological Studies of 5-Aminolevulinic Acid-Containing Dendrimers for Photodynamic Therapy
inferredcites →https://doi.org/10.1021/ja00968a057openalex-snapshot
Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata 1,2
inferredcites →https://doi.org/10.1021/ja409686xopenalex-snapshot
Polyprodrug Amphiphiles: Hierarchical Assemblies for Shape-Regulated Cellular Internalization, Trafficking, and Drug Delivery
inferredcites →https://doi.org/10.1021/jo000221nopenalex-snapshot
20-O-Acylcamptothecin Derivatives: Evidence for Lactone Stabilization
inferredcites →https://doi.org/10.1021/mp900243bopenalex-snapshot
Cancer Therapies Utilizing the Camptothecins: A Review of the in Vivo Literature
inferredcites →https://doi.org/10.1023/b:neon.0000033364.43142.bfopenalex-snapshot
Volume Reconstruction Techniques Improve the Correlation Between Histological and in vivo Tumor Volume Measurements in Mouse Models of Human Gliomas
inferredcites →https://doi.org/10.1038/bjc.2011.12openalex-snapshot
Silencing of ferrochelatase enhances 5-aminolevulinic acid-based fluorescence and photodynamic therapy efficacy
inferredcites →https://doi.org/10.1038/nmeth.1455openalex-snapshot
Coding of facial expressions of pain in the laboratory mouse
inferredcites →https://doi.org/10.1038/nrn1824openalex-snapshot
Astrocyte–endothelial interactions at the blood–brain barrier
inferredcites →https://doi.org/10.1038/s41598-017-09140-1openalex-snapshot
Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug
inferredcites →https://doi.org/10.1038/s42003-019-0560-xopenalex-snapshot
Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblastoma tumor subtyping
inferredcites →https://doi.org/10.1038/srep36086openalex-snapshot
Development and characterization of a microfluidic model of the tumour microenvironment
inferredcites →https://doi.org/10.1039/c3tb20867bopenalex-snapshot
Preparation, characterization, and in vitro evaluation of folate-modified mesoporous bioactive glass for targeted anticancer drug carriers
inferredcites →https://doi.org/10.1042/an20110014openalex-snapshot
Current Review of in Vivo GBM Rodent Models: Emphasis on the CNS-1 Tumour Model
inferredcites →https://doi.org/10.1053/j.seminoncol.2011.09.005openalex-snapshot
Understanding Glioblastoma Tumor Biology: The Potential to Improve Current Diagnosis and Treatments
inferredcites →https://doi.org/10.1056/nejmoa043330openalex-snapshot
Radiotherapy Plus Concomitant and Adjuvant Temozolomide for Glioblastoma
inferredcites →https://doi.org/10.1078/1615-1615-00085openalex-snapshot
5-Aminolevulinic Acid and the Blood-Brain Barrier – A Review
inferredcites →https://doi.org/10.1093/noajnl/vdaa087openalex-snapshot
Metabolism-based isolation of invasive glioblastoma cells with specific gene signatures and tumorigenic potential
inferredcites →https://doi.org/10.1101/gad.1596707openalex-snapshot
Malignant astrocytic glioma: genetics, biology, and paths to treatment
inferredcites →https://doi.org/10.1111/j.1749-6632.1996.tb26375.xopenalex-snapshot
Mechanism of Action of Camptothecin
inferredcites →https://doi.org/10.1111/j.1751-1097.2010.00799.xopenalex-snapshot
5‐Aminolevulinic Acid‐induced Protoporphyrin IX Levels in Tissue of Human Malignant Brain Tumors
inferredcites →https://doi.org/10.1136/vr.116.16.431openalex-snapshot
Guidelines on the recognition of pain, distress and discomfort in experimental animals and an hypothesis for assessment
inferredcites →https://doi.org/10.1159/000455842openalex-snapshot
Temozolomide with or without Radiotherapy in Patients with Newly Diagnosed Glioblastoma Multiforme: A Meta-Analysis
inferredcites →https://doi.org/10.1161/circresaha.116.306534openalex-snapshot
Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability
inferredcites →https://doi.org/10.1186/s40880-018-0335-7openalex-snapshot
Metabolic features of cancer cells
inferredcites →https://doi.org/10.1200/jco.1996.14.12.3056openalex-snapshot
Topotecan, an active drug in the second-line treatment of epithelial ovarian cancer: results of a large European phase II study.
inferredcites →https://doi.org/10.1200/jco.2008.19.8721openalex-snapshot
Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma
inferredcites →https://doi.org/10.1200/jco.2015.63.4691openalex-snapshot
Bevacizumab Plus Irinotecan Versus Temozolomide in Newly Diagnosed O6-Methylguanine–DNA Methyltransferase Nonmethylated Glioblastoma: The Randomized GLARIUS Trial
inferredcites →https://doi.org/10.1371/journal.pone.0181654openalex-snapshot
ALA-PpIX mediated photodynamic therapy of malignant gliomas augmented by hypothermia
inferredcites →https://doi.org/10.1517/14656566.2011.566558openalex-snapshot
Irinotecan and bevacizumab in recurrent glioblastoma multiforme
inferredcites →https://doi.org/10.1523/jneurosci.16-17-05478.1996openalex-snapshot
Astrocyte Growth, Reactivity, and the Target of the Antiproliferative Antibody, TAPA
inferredcites →https://doi.org/10.2174/157489211793980114openalex-snapshot
Metabolic Targeting of Malignant Tumors: Small-Molecule Inhibitors of Bioenergetic Flux
inferredcites →https://doi.org/10.3748/wjg.15.3597openalex-snapshot
Irinotecan therapy and molecular targets in colorectal cancer: A systemic review
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/smll.202510759openalex-snapshot
Prodrug‐Doped ROS‐Responsive Lipid Nanoparticle for Enhanced mRNA Delivery and Synergistic Anti‐Tumor Therapy
inferred← citeshttps://doi.org/10.1007/s10876-026-03102-2openalex-snapshot
Liposomal Camptothecin and its Derivatives: from Molecular Design to Clinical Nanomedicine
inferred← citeshttps://doi.org/10.1007/s10971-023-06218-3openalex-snapshot
A drug delivery system with fluorescent labeling for the delivery and release of the carboxylate-type camptothecin and its cytotoxicity on HepG2 cancer cell
inferred← citeshttps://doi.org/10.1016/b978-0-443-15635-9.00016-xopenalex-snapshot
Prodrugs for cancer therapy
inferred← citeshttps://doi.org/10.1016/b978-0-443-23763-8.00084-1openalex-snapshot
Antitumor effects of natural molecules in the brain: a nanotechnology-based approach
inferred← citeshttps://doi.org/10.1016/j.brainres.2025.149783openalex-snapshot
Unraveling the complexity of glioblastoma microenvironment: A comparative study of 3D and 2D cultures in response to combination drug therapy
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2022.112712openalex-snapshot
A novel carbon-nanodots-based theranostic nano-drug delivery system for mitochondria-targeted imaging and glutathione-activated delivering camptothecin
inferred← citeshttps://doi.org/10.1016/j.ejmech.2025.118535openalex-snapshot
Sinomenine derivative 1f suppresses glioblastoma through inducing both apoptosis mediated by intrinsic pathway and necroptosis mediated by TNF-α/NF-κB/MAPK signaling pathway
inferred← citeshttps://doi.org/10.1016/j.ejps.2023.106561openalex-snapshot
Enhanced cytotoxicity to lung cancer cells by mitochondrial delivery of camptothecin
inferred← citeshttps://doi.org/10.1016/j.jddst.2022.103321openalex-snapshot
Irinotecan-loaded ROS-responsive liposomes containing thioether phosphatidylcholine for improving anticancer activity
inferred← citeshttps://doi.org/10.1016/j.tetlet.2022.153989openalex-snapshot
Development of Camptothecin Nano-Prodrugs Based on Trimethyl Lock Groups Toward Selective Drug Release in Cancer Cells
inferred← citeshttps://doi.org/10.1021/acsanm.4c02757openalex-snapshot
Vegetable Oil–Based Pickering Nanoemulsions As Carriers for Cytosolic Drug Delivery
inferred← citeshttps://doi.org/10.1038/s41598-025-08631-wopenalex-snapshot
Nanoparticles of non-porphyrinic covalent organic frameworks as contrast agents for photoacoustic imaging
inferred← citeshttps://doi.org/10.1039/d1cc04379jopenalex-snapshot
A camptothecin prodrug induces mitochondria-mediated apoptosis in cancer cells with cascade activations
inferred← citeshttps://doi.org/10.1080/17568919.2025.2458455openalex-snapshot
Camptothecin: a key building block in the design of anti-tumor agents
inferred← citeshttps://doi.org/10.1080/20415990.2024.2415281openalex-snapshot
Comprehensive insights into glioblastoma multiforme: drug delivery challenges and multimodal treatment strategies
inferred← citeshttps://doi.org/10.1093/noajnl/vdab192openalex-snapshot
A multiparametric pharmacogenomic strategy for drug repositioning predicts therapeutic efficacy for glioblastoma cell lines
inferred← citeshttps://doi.org/10.1093/noajnl/vdag250openalex-snapshot
Combination chemotherapy potentiates 5-aminolevulic acid-mediated photodynamic therapy killing of patient-derived glioma stem-like cells in vitro
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3131627/v1openalex-snapshot
Comparison of 3D and 2D cultures for evaluating the effect of combination therapy with Erlotinib and Imatinib on Glioblastoma multiforme
inferred← citeshttps://doi.org/10.3390/ijms27083705openalex-snapshot
Liposomal Encapsulation of Camptothecin/Carboxymethyl-β-Cyclodextrin Complexes: Stability, Solubility and Cytotoxicity
inferred← citeshttps://doi.org/10.3390/pharmaceutics18060712openalex-snapshot
Advances in Camptothecin-Class Compounds Nanomedicines: A Comprehensive Review of Antitumor Strategies
inferred← citeshttps://doi.org/10.3390/polym13162670openalex-snapshot
Targeted Gold Nanohybrids Functionalized with Folate-Hydrophobic-Quaternized Pullulan Delivering Camptothecin for Enhancing Hydrophobic Anticancer Drug Efficacy
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