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Diterpenoids with Rearranged 9(10→11)-abeo-10,12-Cyclojatrophane Skeleton and the First (15S)-Jatrophane from Euphorbia helioscopia: Structural Elucidation, Biomimetic Conversion, and Their Immunosuppressive Effects

https://doi.org/10.1021/acs.orglett.1c04145

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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New Bioactive Macrocyclic Diterpenoids from Euphorbia helioscopia

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The lymphocyte potassium channels Kv1.3 and KCa3.1 as targets for immunosuppression

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Progress in the Preparation of Jatrophane Diterpenes

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Diterpenes from Euphorbia helioscopia

inferredcites →https://doi.org/10.1016/j.apsb.2018.03.011openalex-snapshot

Helioscopianoids A–Q, bioactive jatrophane diterpenoid esters from Euphorbia helioscopia

inferredcites →https://doi.org/10.1016/j.bioorg.2019.103237openalex-snapshot

NO inhibitory diterpenoids as potential anti-inflammatory agents from Euphorbia antiquorum

inferredcites →https://doi.org/10.1016/j.bioorg.2020.103763openalex-snapshot

Euphoresulanes A–M, structurally diverse jatrophane diterpenoids from Euphorbia esula

inferredcites →https://doi.org/10.1016/j.bioorg.2021.104944openalex-snapshot

Diterpenoids from the seeds of Euphorbia lathyris and their anti-inflammatory activity

inferredcites →https://doi.org/10.1016/j.bioorg.2021.104989openalex-snapshot

Jatrophane diterpenoids as multidrug resistance modulators from Euphorbia sororia

inferredcites →https://doi.org/10.1016/j.biopha.2019.109663openalex-snapshot

Lathyrane diterpenes from Euphorbia lathyris and the potential mechanism to reverse the multi-drug resistance in HepG2/ADR cells

inferredcites →https://doi.org/10.1016/j.phytochem.2017.10.012openalex-snapshot

Highly oxygenated and structurally diverse diterpenoids from Euphorbia helioscopia

inferredcites →https://doi.org/10.1016/j.phytochem.2020.112257openalex-snapshot

Ingenane and jatrophane diterpenoids from Euphorbia kansui and their antiproliferative effects

inferredcites →https://doi.org/10.1016/j.phytochem.2020.112519openalex-snapshot

Bond reactivity indices approach analysis of the [2+2] cycloaddition of jatrophane skeleton diterpenoids from Euphorbia gaditana Coss to tetracyclic gaditanone

inferredcites →https://doi.org/10.1016/j.phytochem.2021.112775openalex-snapshot

Ingenane and jatrophane-type diterpenoids from Euphorbia kansui with multidrug resistance reversal activity

inferredcites →https://doi.org/10.1016/s0031-9422(97)00830-3openalex-snapshot

Diterpenes from Euphorbia segetalis

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Ion channels in the immune system as targets for immunosuppression

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Jatrophane Diterpenoids from Euphorbia peplus as Multidrug Resistance Modulators with Inhibitory Effects on the ATR-Chk-1 Pathway

inferredcites →https://doi.org/10.1021/acs.jnatprod.5b00511openalex-snapshot

Advanced Structural Determination of Diterpene Esters Using Molecular Modeling and NMR Spectroscopy

inferredcites →https://doi.org/10.1021/acs.jnatprod.7b00332openalex-snapshot

Gaditanone, a Diterpenoid Based on an Unprecedented Carbon Skeleton Isolated from Euphorbia gaditana

inferredcites →https://doi.org/10.1021/acs.jnatprod.8b00507openalex-snapshot

Jatrophane Diterpenoids from Euphorbia glomerulans

inferredcites →https://doi.org/10.1021/acs.jnatprod.8b00780openalex-snapshot

Euphorhelipanes A and B, Triglyceride-Lowering Euphorbia Diterpenoids with a Bicyclo[4.3.0]nonane Core from Euphorbia helioscopia

inferredcites →https://doi.org/10.1021/acs.jnatprod.8b01087openalex-snapshot

Studies of Jatrogossone A as a Reactive Oxygen Species Inducer in Cancer Cellular Models

inferredcites →https://doi.org/10.1021/acs.jnatprod.9b00519openalex-snapshot

Macrocyclic Diterpenoids from Euphorbia helioscopia and Their Potential Anti-inflammatory Activity

inferredcites →https://doi.org/10.1021/acs.jnatprod.9b00929openalex-snapshot

Jatrophane Diterpenoids from Euphorbia esula as Inhibitors of RANKL-Induced Osteoclastogenesis

inferredcites →https://doi.org/10.1021/acs.joc.7b02558openalex-snapshot

Secoheliosphanes A and B and Secoheliospholane A, Three Diterpenoids with Unusual seco-Jatrophane and seco-Jatropholane Skeletons from Euphorbia helioscopia

inferredcites →https://doi.org/10.1021/acs.orglett.0c02676openalex-snapshot

Euphopias A–C: Three Rearranged Jatrophane Diterpenoids with Tricyclo[8.3.0.02,7]tridecane and Tetracyclo[11.3.0.02,10.03,7]hexadecane Cores from Euphorbia helioscopia

inferredcites →https://doi.org/10.1021/acs.orglett.6b00787openalex-snapshot

Three Minor Diterpenoids with Three Carbon Skeletons from Euphorbia peplus

inferredcites →https://doi.org/10.1021/acs.orglett.8b01114openalex-snapshot

Pepluanols C–D, Two Diterpenoids with Two Skeletons from Euphorbia peplus

inferredcites →https://doi.org/10.1021/acs.orglett.8b01215openalex-snapshot

Heliojatrones A and B, Two Jatrophane-Derived Diterpenoids with a 5/10 Fused-Ring Skeleton from Euphorbia helioscopia: Structural Elucidation and Biomimetic Conversion

inferredcites →https://doi.org/10.1021/acs.orglett.9b04029openalex-snapshot

Jatrofolianes A and B: Two Highly Modified Lathyrane Diterpenoids from Jatropha gossypiifolia

inferredcites →https://doi.org/10.1021/cr078350sopenalex-snapshot

Chemical and Pharmacological Research of the Plants in Genus Euphorbia

inferredcites →https://doi.org/10.1021/cr400541jopenalex-snapshot

Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)

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Synthetic Aspects of the Di-π-methane Rearrangement

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Mechanism of the Oxadi-π-methane and [1,3]-Acyl Sigmatropic Rearrangements of β,γ-Enones: A Theoretical Study

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Jatrophane Diterpenes as Inhibitors of Chikungunya Virus Replication: Structure–Activity Relationship and Discovery of a Potent Lead

inferredcites →https://doi.org/10.1021/ol049263eopenalex-snapshot

Influence of Electron-Donor Sensitizers on SET-Promoted Photochemical Reactions of β,γ-Unsaturated Aldehydes

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Novel Oxa-di-π-methane and Norrish Type I Reactions in the S2 (π,π*) Excited State of a Series of β,γ-Unsaturated Ketones

inferredcites →https://doi.org/10.1021/ol701454vopenalex-snapshot

Biogenetical Related Highly Oxygenated Macrocyclic Diterpenes from Sea Spurge Euphorbia paralias

inferredcites →https://doi.org/10.1038/nri3233openalex-snapshot

Ion channels and transporters in lymphocyte function and immunity

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Biologically active diterpenes containing a gem-dimethylcyclopropane subunit: an intriguing source of PKC modulators

inferredcites →https://doi.org/10.1039/d1qo00396hopenalex-snapshot

Euphopias D–F from Euphorbia L.: quantum chemical calculation-based structure elucidation and their bioactivity of inhibiting NLRP3 inflammasome activation

inferredcites →https://doi.org/10.1055/s-2005-837832openalex-snapshot

Three New Jatrophone-Type Diterpenoids fromEuphorbia helioscopia

inferredcites →https://doi.org/10.1111/j.1600-065x.2009.00816.xopenalex-snapshot

The functional network of ion channels in T lymphocytes

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Chemical Studies on the Constituents of the Chinese Medicinal Herb Euphorbia helioscopia L.

inferredcites →https://doi.org/10.3390/molecules26165055openalex-snapshot

Euphorbia Diterpenes: An Update of Isolation, Structure, Pharmacological Activities and Structure–Activity Relationship

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Recent Advances of Terpenoids with Intriguing Chemical Skeletons and Biological Activities

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inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113444openalex-snapshot

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Three new abietane diterpenoids from the aerial parts of Euphorbia fischeriana and their cytotoxic effects

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Scandium-Catalyzed Skeleton Conversion of Lathyrane to Lathyranone-Type Euphorbia Diterpenes

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Ir-Catalyzed Biomimetic Photoisomerization of Cyclopropane in Lathyrane-Type Euphorbia Diterpenes

inferred← citeshttps://doi.org/10.1021/acs.orglett.3c03109openalex-snapshot

Rearrangement of the Tetra- and Tricyclic Skeletons of Pepluanol B to Access the Core Structures of Tigliane- and Myrsinane-Type Euphorbia Diterpenes

inferred← citeshttps://doi.org/10.1021/acs.orglett.5c01770openalex-snapshot

Biomimetic Skeleton Conversion from Lathyrane into Euphoractine A-Type Euphorbia Diterpenes: Semisynthesis of Natural Diterpenes Euphoractins M and N

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Stelleroids A–C, Three Rearranged Guaiane Sesquiterpenoids with Caged Ring Systems from Stellera chamaejasme

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Rearranged Jatrophane Diterpenoids from Euphorbia helioscopia with 5/6/6/4 and 5/6/6/5 Fused Skeletons and Potent Anti-ZIKV Activity

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Euphorbia diterpenoids: isolation, structure, bioactivity, biosynthesis, and synthesis (2013–2021)

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