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A Modular Approach for Facile Biosynthesis of Labdane-Related Diterpenes

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bit.20128openalex-snapshot
Mono and diterpene production in Escherichia coli
inferredcites →https://doi.org/10.1016/j.abb.2005.09.001openalex-snapshot
An unexpected diterpene cyclase from rice: Functional identification of a stemodene synthase
inferredcites →https://doi.org/10.1016/j.phytochem.2006.10.016openalex-snapshot
Functional characterization of the rice kaurene synthase-like gene family
inferredcites →https://doi.org/10.1021/bi001997lopenalex-snapshot
Abietadiene Synthase from Grand Fir (Abies grandis): Characterization and Mechanism of Action of the “Pseudomature” Recombinant Enzyme
inferredcites →https://doi.org/10.1021/ja010670kopenalex-snapshot
Bifunctional Abietadiene Synthase: Free Diffusive Transfer of the (+)-Copalyl Diphosphate Intermediate between Two Distinct Active Sites
inferredcites →https://doi.org/10.1021/ja072447eopenalex-snapshot
16-Aza-ent-beyerane and 16-Aza-ent-trachylobane: Potent Mechanism-Based Inhibitors of Recombinant ent-Kaurene Synthase from Arabidopsis thaliana
inferredcites →https://doi.org/10.1021/ol034231xopenalex-snapshot
Metabolic Engineering to Produce Sesquiterpenes in Yeast
inferredcites →https://doi.org/10.1038/nbt833openalex-snapshot
Engineering a mevalonate pathway in Escherichia coli for production of terpenoids
inferredcites →https://doi.org/10.1038/nchembio836openalex-snapshot
Production of isoprenoid pharmaceuticals by engineered microbes
inferredcites →https://doi.org/10.1074/jbc.m105900200openalex-snapshot
Interaction with the Small Subunit of Geranyl Diphosphate Synthase Modifies the Chain Length Specificity of Geranylgeranyl Diphosphate Synthase to Produce Geranyl Diphosphate
inferredcites →https://doi.org/10.1074/jbc.m206382200openalex-snapshot
Functiona l Analysis of Eubacterial Diterpene Cyclases Responsible for Biosynthesis of a Diterpene Antibiotic, Terpentecin
inferredcites →https://doi.org/10.1104/pp.104.045971openalex-snapshot
Identification of Syn-Pimara-7,15-Diene Synthase Reveals Functional Clustering of Terpene Synthases Involved in Rice Phytoalexin/Allelochemical Biosynthesis
inferredcites →https://doi.org/10.1104/pp.106.095208openalex-snapshot
Synergistic Substrate Inhibition of ent-Copalyl Diphosphate Synthase: A Potential Feed-Forward Inhibition Mechanism Limiting Gibberellin Metabolism
inferredcites →https://doi.org/10.1111/j.1365-313x.2004.02137.xopenalex-snapshot
Functional identification of rice syn‐copalyl diphosphate synthase and its role in initiating biosynthesis of diterpenoid phytoalexin/allelopathic natural products
inferredcites →https://doi.org/10.5860/choice.38-3895openalex-snapshot
Biochemistry & molecular biology of plants

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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A pair of threonines mark ent-kaurene synthases for phytohormone biosynthesis
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Organic Synthesis with Isomerases
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Rhodophyceae (Red Algae)
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Biosynthetic Pathway Engineering Strategies
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Novel Product Chemistry from Mechanistic Analysis of ent‐Copalyl Diphosphate Synthases from Plant Hormone Biosynthesis
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Blocking Deprotonation with Retention of Aromaticity in a Plant ent‐Copalyl Diphosphate Synthase Leads to Product Rearrangement
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Expanding the Landscape of Diterpene Structural Diversity through Stereochemically Controlled Combinatorial Biosynthesis
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Entdeckung und Biosynthese eines strukturdynamischen antibakteriellen Diterpenoids
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Novel Product Chemistry from Mechanistic Analysis of ent ‐Copalyl Diphosphate Synthases from Plant Hormone Biosynthesis
inferred← citeshttps://doi.org/10.1002/anie.201509060openalex-snapshot
Blocking Deprotonation with Retention of Aromaticity in a Plant ent‐Copalyl Diphosphate Synthase Leads to Product Rearrangement
inferred← citeshttps://doi.org/10.1002/anie.201510650openalex-snapshot
Expanding the Landscape of Diterpene Structural Diversity through Stereochemically Controlled Combinatorial Biosynthesis
inferred← citeshttps://doi.org/10.1002/anie.202102453openalex-snapshot
Discovery and Biosynthesis of a Structurally Dynamic Antibacterial Diterpenoid
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Diterpenoid biopolymers: New directions for renewable materials engineering
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A Novel Labda‐7,13 E ‐dien‐15‐ol‐Producing Bifunctional Diterpene Synthase from Selaginella moellendorffii
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Targeted Engineering of Cyclooctat‐9‐en‐7‐ol Synthase: A Stereospecific Access to Two New Non‐natural Fusicoccane‐Type Diterpenes
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Diterpene cyclases and the nature of the isoprene fold
inferred← citeshttps://doi.org/10.1007/10_2014_301openalex-snapshot
Cytochromes P450 for Terpene Functionalisation and Metabolic Engineering
inferred← citeshttps://doi.org/10.1007/978-3-319-12108-6_8openalex-snapshot
P450 Biotechnology
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Endophytes as Source of High-Value Phytochemicals: Present Scenario and Future Outlook
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Endophytes as a Source of High-Value Phytochemicals: Present Scenario and Future Outlook
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Molecular Mechanisms and Gene Regulation for Biosynthesis of Medicinal Plant Active Ingredients
inferred← citeshttps://doi.org/10.1007/s00253-009-2219-xopenalex-snapshot
Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering
inferred← citeshttps://doi.org/10.1007/s00253-015-6496-2openalex-snapshot
Optimization of recombinant expression enables discovery of novel cytochrome P450 activity in rice diterpenoid biosynthesis
inferred← citeshttps://doi.org/10.1007/s00299-018-2353-yopenalex-snapshot
Molecular cloning and functional characterization of multiple geranylgeranyl pyrophosphate synthases (ApGGPPS) from Andrographis paniculata
inferred← citeshttps://doi.org/10.1007/s00425-016-2570-yopenalex-snapshot
Functional characterization of ZmTPS7 reveals a maize τ-cadinol synthase involved in stress response
inferred← citeshttps://doi.org/10.1007/s10529-015-1961-7openalex-snapshot
Functional characterization of ent-copalyl diphosphate synthase from Andrographis paniculata with putative involvement in andrographolides biosynthesis
inferred← citeshttps://doi.org/10.1007/s11103-019-00881-3openalex-snapshot
CYP71Z18 overexpression confers elevated blast resistance in transgenic rice
inferred← citeshttps://doi.org/10.1007/s11418-017-1168-4openalex-snapshot
Characterization of ent-kaurene synthase and kaurene oxidase involved in gibberellin biosynthesis from Scoparia dulcis
inferred← citeshttps://doi.org/10.1007/s42994-022-00092-3openalex-snapshot
Oryzalexin S biosynthesis: a cross-stitched disappearing pathway
inferred← citeshttps://doi.org/10.1007/s42994-024-00167-3openalex-snapshot
Double-barreled defense: dual ent-miltiradiene synthases in most rice cultivars
inferred← citeshttps://doi.org/10.1016/b978-0-12-394290-6.00008-2openalex-snapshot
Platensimycin and Platencin Biosynthesis in Streptomyces platensis, Showcasing Discovery and Characterization of Novel Bacterial Diterpene Synthases
inferred← citeshttps://doi.org/10.1016/b978-0-12-404634-4.00006-1openalex-snapshot
Finding and Analyzing Plant Metabolic Gene Clusters
inferred← citeshttps://doi.org/10.1016/b978-0-12-405927-6.00003-5openalex-snapshot
Diterpenoids from the Medicinal Plants of Africa
inferred← citeshttps://doi.org/10.1016/b978-008045382-8.00005-8openalex-snapshot
Sesquiterpenes
inferred← citeshttps://doi.org/10.1016/bs.mie.2023.11.002openalex-snapshot
Methods for the preparation and analysis of a bifunctional class II diterpene synthase, copalyl diphosphate synthase from Penicillium fellutanum
inferred← citeshttps://doi.org/10.1016/j.apsb.2021.04.008openalex-snapshot
Functional identification of the terpene synthase family involved in diterpenoid alkaloids biosynthesis in Aconitum carmichaelii
inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.07.028openalex-snapshot
Characterization of diterpene synthase genes in the wild rice species Oryza brachyatha provides evolutionary insight into rice phytoalexin biosynthesis
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2016.03.005openalex-snapshot
The potential of the mevalonate pathway for enhanced isoprenoid production
inferred← citeshttps://doi.org/10.1016/j.cbpa.2012.03.002openalex-snapshot
Bacterial diterpene synthases: new opportunities for mechanistic enzymology and engineered biosynthesis
inferred← citeshttps://doi.org/10.1016/j.copbio.2013.10.009openalex-snapshot
Gene clustering in plant specialized metabolism
inferred← citeshttps://doi.org/10.1016/j.febslet.2008.12.052openalex-snapshot
Gibberellin biosynthesis in bacteria: Separate ent ‐copalyl diphosphate and ent ‐kaurene synthases in Bradyrhizobium japonicum
inferred← citeshttps://doi.org/10.1016/j.febslet.2011.09.038openalex-snapshot
Parsing a multifunctional biosynthetic gene cluster from rice: Biochemical characterization of CYP71Z6 & 7
inferred← citeshttps://doi.org/10.1016/j.jbc.2024.107921openalex-snapshot
The crystal structure of Grindelia robusta 7,13-copalyl diphosphate synthase reveals active site features controlling catalytic specificity
inferred← citeshttps://doi.org/10.1016/j.molp.2014.12.002openalex-snapshot
The Application of Synthetic Biology to Elucidation of Plant Mono-, Sesqui-, and Diterpenoid Metabolism
inferred← citeshttps://doi.org/10.1016/j.molp.2026.07.004openalex-snapshot
A minimal four-enzyme suite enables biosynthesis of the C20 diterpenoid alkaloid atisinium
inferred← citeshttps://doi.org/10.1016/j.phytochem.2008.12.022openalex-snapshot
Investigating the conservation pattern of a putative second terpene synthase divalent metal binding motif in plants
inferred← citeshttps://doi.org/10.1016/j.phytochem.2012.08.021openalex-snapshot
Functional characterization of wheat ent-kaurene(-like) synthases indicates continuing evolution of labdane-related diterpenoid metabolism in the cereals
inferred← citeshttps://doi.org/10.1016/j.phytochem.2012.08.022openalex-snapshot
Functional characterization of wheat copalyl diphosphate synthases sheds light on the early evolution of labdane-related diterpenoid metabolism in the cereals
inferred← citeshttps://doi.org/10.1016/j.phytochem.2014.04.005openalex-snapshot
Biochemical characterization of the castor bean ent -kaurene synthase(-like) family supports quantum chemical view of diterpene cyclization
inferred← citeshttps://doi.org/10.1016/j.phytochem.2015.10.003openalex-snapshot
Characterization of CYP71Z18 indicates a role in maize zealexin biosynthesis
inferred← citeshttps://doi.org/10.1016/j.phytochem.2018.11.015openalex-snapshot
Diterpene synthases facilitating production of the kaurane skeleton of eriocalyxin B in the medicinal plant Isodon eriocalyx
inferred← citeshttps://doi.org/10.1016/j.phytochem.2025.114459openalex-snapshot
Exploring evolutionary use of single residue switches for alternative product outcome in class II diterpene cyclases
inferred← citeshttps://doi.org/10.1016/j.phytochem.2025.114634openalex-snapshot
Uncrossing the ‘X’: Characterization of alternative alleles for KSLX in Oryza
inferred← citeshttps://doi.org/10.1016/j.phytochem.2025.114635openalex-snapshot
Investigating conserved aromatic residues in ent-copalyl pyrophosphate synthases required for gibberellin phytohormone biosynthesis
inferred← citeshttps://doi.org/10.1016/j.phytochem.2026.114886openalex-snapshot
Comprehensive genomic analysis reveals the class II diterpene cyclases in Dodonaea viscosa
inferred← citeshttps://doi.org/10.1016/j.plantsci.2015.08.016openalex-snapshot
Involvement of an ent-copalyl diphosphate synthase in tissue-specific accumulation of specialized diterpenes in Andrographis paniculata
inferred← citeshttps://doi.org/10.1016/j.plantsci.2024.112046openalex-snapshot
ApCPS2 contributes to medicinal diterpenoid biosynthesis and defense against insect herbivore in Andrographis paniculata
inferred← citeshttps://doi.org/10.1016/j.plaphy.2015.07.011openalex-snapshot
Additional diterpenes from Physcomitrella patens synthesized by copalyl diphosphate/kaurene synthase (PpCPS/KS)
inferred← citeshttps://doi.org/10.1016/j.plaphy.2023.107968openalex-snapshot
Functional diversity of diterpene synthases in Aconitum plants
inferred← citeshttps://doi.org/10.1016/j.synbio.2026.08.004openalex-snapshot
Characterization of two key cytochrome P450 enzymes in Isodon amethystoides and de novo production of 3α,15β-dihydroxy-ent-kaurene in yeast
inferred← citeshttps://doi.org/10.1016/j.tet.2014.10.015openalex-snapshot
Synthetic applications of homoiodo allylsilane II. Total syntheses of (−)-andrographolide and (+)-rostratone
inferred← citeshttps://doi.org/10.1016/j.tet.2014.12.026openalex-snapshot
Opportunities for enzyme catalysis in natural product chemistry
inferred← citeshttps://doi.org/10.1016/j.tibtech.2015.04.006openalex-snapshot
Plant diterpene synthases: exploring modularity and metabolic diversity for bioengineering
inferred← citeshttps://doi.org/10.1016/j.ymben.2016.04.001openalex-snapshot
Extreme promiscuity of a bacterial and a plant diterpene synthase enables combinatorial biosynthesis
inferred← citeshttps://doi.org/10.1016/j.ymben.2019.06.008openalex-snapshot
Combinatorial biosynthesis and the basis for substrate promiscuity in class I diterpene synthases
inferred← citeshttps://doi.org/10.1016/j.ymben.2022.08.001openalex-snapshot
De novo production of versatile oxidized kaurene diterpenes in Escherichia coli
inferred← citeshttps://doi.org/10.1021/acs.biochem.8b00193openalex-snapshot
Catalytic Bases and Stereocontrol in Lamiaceae Class II Diterpene Cyclases
inferred← citeshttps://doi.org/10.1021/acs.jafc.0c03488openalex-snapshot
Divergent Evolution of the Diterpene Biosynthesis Pathway in Tea Plants (Camellia sinensis) Caused by Single Amino Acid Variation of ent-Kaurene Synthase
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.1c00588openalex-snapshot
Mining of the Catharanthus roseus Genome Leads to Identification of a Biosynthetic Gene Cluster for Fungicidal Sesquiterpenes
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6b00764openalex-snapshot
Probing Labdane-Related Diterpenoid Biosynthesis in the Fungal Genus Aspergillus
inferred← citeshttps://doi.org/10.1021/acs.orglett.2c00680openalex-snapshot
Deceptive Complexity in Formation of Cleistantha-8,12-diene
inferred← citeshttps://doi.org/10.1021/acs.orglett.5c00858openalex-snapshot
The Pursuit of a Hydroxylation Switch Uncovers a Key Residue for Various Product Outcomes in the ent-Kaurene Synthase from Bradyrhizobium japonicum
inferred← citeshttps://doi.org/10.1021/acs.orglett.5c04898openalex-snapshot
Exploring a Unique Class II Diterpene Cyclase: The Modified Catalytic Acid Motif Contributes to Ring Contraction in Premutilin Synthase
inferred← citeshttps://doi.org/10.1021/acs.orglett.6b00181openalex-snapshot
Product Rearrangement from Altering a Single Residue in the Rice syn -Copalyl Diphosphate Synthase
inferred← citeshttps://doi.org/10.1021/acs.orglett.8b00121openalex-snapshot
Premutilin Synthase: Ring Rearrangement by a Class II Diterpene Cyclase
inferred← citeshttps://doi.org/10.1021/acscatal.3c05918openalex-snapshot
From Functional Plasticity of Two Diterpene Synthases (IrTPS2/IrKSL3a) to Enzyme Evolution
inferred← citeshttps://doi.org/10.1021/acscatal.6b01332openalex-snapshot
A Catalytically Competent Terpene Synthase Inferred Using Ancestral Sequence Reconstruction Strategy
inferred← citeshttps://doi.org/10.1021/acscatal.8b00121openalex-snapshot
Changing Face: A Key Residue for the Addition of Water by Sclareol Synthase
inferred← citeshttps://doi.org/10.1021/acschembio.6b01075openalex-snapshot
A Pair of Residues That Interactively Affect Diterpene Synthase Product Outcome
inferred← citeshttps://doi.org/10.1021/ja307404uopenalex-snapshot
Toward a Biosynthetic Route to Sclareol and Amber Odorants
inferred← citeshttps://doi.org/10.1021/ja508477eopenalex-snapshot
Biosynthesis of Lycosantalonol, a cis -Prenyl Derived Diterpenoid
inferred← citeshttps://doi.org/10.1021/ja710524wopenalex-snapshot
Increasing Complexity of a Diterpene Synthase Reaction with a Single Residue Switch
inferred← citeshttps://doi.org/10.1021/jacs.6b09818openalex-snapshot
Biosynthetic Origin of the Ether Ring in Platensimycin
inferred← citeshttps://doi.org/10.1021/jacs.6c03321openalex-snapshot
The One Ring: A Monocycle Producing Class II Diterpene Cyclase from Isodon leucophyllus
inferred← citeshttps://doi.org/10.1021/np500422dopenalex-snapshot
Characterization of an Orphan Diterpenoid Biosynthetic Operon from Salinispora arenicola
inferred← citeshttps://doi.org/10.1021/ol3026022openalex-snapshot
A Single Residue Change Leads to a Hydroxylated Product from the Class II Diterpene Cyclization Catalyzed by Abietadiene Synthase
inferred← citeshttps://doi.org/10.1021/ol8011919openalex-snapshot
Structure Revision and Synthesis of a Novel Labdane Diterpenoid from Zingiber ottensii
inferred← citeshttps://doi.org/10.1021/ol902051vopenalex-snapshot
A Functional Genomics Approach to Tanshinone Biosynthesis Provides Stereochemical Insights
inferred← citeshttps://doi.org/10.1038/s41477-019-0582-xopenalex-snapshot
Introducing selective agrochemical manipulation of gibberellin metabolism into a cereal crop
inferred← citeshttps://doi.org/10.1038/s41598-020-66866-1openalex-snapshot
Diversity and function of terpene synthases in the production of carrot aroma and flavor compounds
inferred← citeshttps://doi.org/10.1039/b807311mopenalex-snapshot
Diterpenoids
inferred← citeshttps://doi.org/10.1039/c0np00035copenalex-snapshot
Biosynthesis, total syntheses, and antitumor activity of tanshinones and their analogs as potential therapeutic agents
inferred← citeshttps://doi.org/10.1039/c3ob41885eopenalex-snapshot
Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae
inferred← citeshttps://doi.org/10.1039/c5cc05754jopenalex-snapshot
Efficient heterocyclisation by (di)terpene synthases
inferred← citeshttps://doi.org/10.1039/c7ob00510eopenalex-snapshot
cis or trans with class II diterpene cyclases
inferred← citeshttps://doi.org/10.1039/d5ob01208bopenalex-snapshot
Phylogeny-directed discovery and mutagenesis of a tricyclic gersemiane synthase
inferred← citeshttps://doi.org/10.1042/bcj20190479openalex-snapshot
Conserved bases for the initial cyclase in gibberellin biosynthesis: from bacteria to plants
inferred← citeshttps://doi.org/10.1042/bcj20250232openalex-snapshot
Peeking behind the carbocation: identification of (alternative) catalytic bases in the class II active site of conifer resin acid diterpene synthases
inferred← citeshttps://doi.org/10.1042/bcj20250294openalex-snapshot
Docking in the Abies grandis abietaenol synthase to investigate the mechanism underlying conifer resin acid diterpene synthase evolution
inferred← citeshttps://doi.org/10.1042/bj20101429openalex-snapshot
Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals
inferred← citeshttps://doi.org/10.1042/bj20130574openalex-snapshot
Picking sides: distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis
inferred← citeshttps://doi.org/10.1070/rc2014v083n04abeh004396openalex-snapshot
Bacterial transformation of terpenoids
inferred← citeshttps://doi.org/10.1073/pnas.0611454104openalex-snapshot
Following evolution's lead to a single residue switch for diterpene synthase product outcome
inferred← citeshttps://doi.org/10.1073/pnas.1006138107openalex-snapshot
Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control
inferred← citeshttps://doi.org/10.1073/pnas.1218061110openalex-snapshot
CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts
inferred← citeshttps://doi.org/10.1073/pnas.1512096113openalex-snapshot
Probing the promiscuity of ent -kaurene oxidases via combinatorial biosynthesis
inferred← citeshttps://doi.org/10.1073/pnas.2100361119openalex-snapshot
Origin and early evolution of the plant terpene synthase family
inferred← citeshttps://doi.org/10.1073/pnas.2510962122openalex-snapshot
Favorable epistasis in ancestral diterpene synthases promoted convergent evolution of a resin acid precursor in conifers
inferred← citeshttps://doi.org/10.1074/jbc.m111.231787openalex-snapshot
Sandalwood Fragrance Biosynthesis Involves Sesquiterpene Synthases of Both the Terpene Synthase (TPS)-a and TPS-b Subfamilies, including Santalene Synthases
inferred← citeshttps://doi.org/10.1074/jbc.m111.305599openalex-snapshot
Characterization of CYP76M5–8 Indicates Metabolic Plasticity within a Plant Biosynthetic Gene Cluster
inferred← citeshttps://doi.org/10.1074/jbc.m111.337592openalex-snapshot
Insights into Diterpene Cyclization from Structure of Bifunctional Abietadiene Synthase from Abies grandis
inferred← citeshttps://doi.org/10.1093/hr/uhae221openalex-snapshot
Discovery of bifunctional diterpene cyclases/synthases in bacteria supports a bacterial origin for the plant terpene synthase gene family
inferred← citeshttps://doi.org/10.1093/jimb/kuae003openalex-snapshot
Development of platensimycin, platencin, and platensilin overproducers by biosynthetic pathway engineering and fermentation medium optimization
inferred← citeshttps://doi.org/10.1093/plcell/koaa023openalex-snapshot
Interdependent evolution of biosynthetic gene clusters for momilactone production in rice
inferred← citeshttps://doi.org/10.1093/plphys/kiac056openalex-snapshot
Diterpene synthases fromLeonurus japonicuselucidate epoxy-bridge formation of spiro-labdane diterpenoids
inferred← citeshttps://doi.org/10.1093/plphys/kiag292openalex-snapshot
Genome-wide discovery and characterization of terpene synthases contributing to strawberry aroma metabolism
inferred← citeshttps://doi.org/10.1094/mpmi-01-17-0001-ropenalex-snapshot
Investigating the Phylogenetic Range of Gibberellin Biosynthesis in Bacteria
inferred← citeshttps://doi.org/10.1104/pp.111.179648openalex-snapshot
The Tomato Terpene Synthase Gene Family
inferred← citeshttps://doi.org/10.1104/pp.111.187518openalex-snapshot
CYP701A8: A Rice ent -Kaurene Oxidase Paralog Diverted to More Specialized Diterpenoid Metabolism
inferred← citeshttps://doi.org/10.1104/pp.15.01727openalex-snapshot
A Tandem Array of ent -Kaurene Synthases in Maize with Roles in Gibberellin and More Specialized Metabolism
inferred← citeshttps://doi.org/10.1104/pp.17.00659openalex-snapshot
Biosynthesis of Diterpenoids in Tripterygium Adventitious Root Cultures
inferred← citeshttps://doi.org/10.1105/tpc.108.063677openalex-snapshot
CYP76M7 Is an ent -Cassadiene C11α-Hydroxylase Defining a Second Multifunctional Diterpenoid Biosynthetic Gene Cluster in Rice
inferred← citeshttps://doi.org/10.1105/tpc.112.100057openalex-snapshot
Formation of the Unusual Semivolatile Diterpene Rhizathalene by the Arabidopsis Class I Terpene Synthase TPS08 in the Root Stele Is Involved in Defense against Belowground Herbivory
inferred← citeshttps://doi.org/10.1105/tpc.16.00062openalex-snapshot
Molecular Diversity of Terpene Synthases in the Liverwort Marchantia polymorpha
inferred← citeshttps://doi.org/10.1107/s2053230x15014363openalex-snapshot
Crystallization and X-ray diffraction analysis of a putative bacterial class I labdane-related diterpene synthase
inferred← citeshttps://doi.org/10.1111/j.1365-2958.2011.07545.xopenalex-snapshot
Magnesium depletion triggers production of an immune modulating diterpenoid in Mycobacterium tuberculosis
inferred← citeshttps://doi.org/10.1111/j.1365-313x.2010.04408.xopenalex-snapshot
CYP99A3: functional identification of a diterpene oxidase from the momilactone biosynthetic gene cluster in rice
inferred← citeshttps://doi.org/10.1111/j.1365-313x.2011.04756.xopenalex-snapshot
Domain loss has independently occurred multiple times in plant terpene synthase evolution
inferred← citeshttps://doi.org/10.1111/jipb.70262openalex-snapshot
Divergent roles of ent ‐kaurene oxidase paralogs in rice momilactone biosynthesis
inferred← citeshttps://doi.org/10.1111/nph.13187openalex-snapshot
An ent‐kaurene‐derived diterpenoid virulence factor from X anthomonas oryzae pv. oryzicola
inferred← citeshttps://doi.org/10.1111/nph.15778openalex-snapshot
Promiscuous terpene synthases from Prunella vulgaris highlight the importance of substrate and compartment switching in terpene synthase evolution
inferred← citeshttps://doi.org/10.1111/nph.17351openalex-snapshot
Discovery and modulation of diterpenoid metabolism improves glandular trichome formation, artemisinin production and stress resilience in Artemisia annua
inferred← citeshttps://doi.org/10.1111/nph.17406openalex-snapshot
Rice contains a biosynthetic gene cluster associated with production of the casbane‐type diterpenoid phytoalexin ent ‐10‐oxodepressin
inferred← citeshttps://doi.org/10.1111/plb.13708openalex-snapshot
Characterization of switchgrass ( Panicum virgatum L.) PvKSL1 as a levopimaradiene/abietadiene‐type diterpene synthase
inferred← citeshttps://doi.org/10.1111/tpj.13756openalex-snapshot
Identification and functional characterization of diterpene synthases for triptolide biosynthesis from Tripterygium wilfordii
inferred← citeshttps://doi.org/10.1111/tpj.13901openalex-snapshot
Direct production of dihydroxylated sesquiterpenoids by a maize terpene synthase
inferred← citeshttps://doi.org/10.1111/tpj.14162openalex-snapshot
The genome of the medicinal plant Andrographis paniculata provides insight into the biosynthesis of the bioactive diterpenoid neoandrographolide
inferred← citeshttps://doi.org/10.1111/tpj.14771openalex-snapshot
The foxtail millet ( Setaria italica ) terpene synthase gene family
inferred← citeshttps://doi.org/10.1111/tpj.14957openalex-snapshot
The biosynthesis of the anti‐microbial diterpenoid leubethanol in Leucophyllum frutescens proceeds via an all‐cis prenyl intermediate
inferred← citeshttps://doi.org/10.1111/tpj.15492openalex-snapshot
Cytochrome P450‐catalyzed biosynthesis of furanoditerpenoids in the bioenergy crop switchgrass ( Panicum virgatum L.)
inferred← citeshttps://doi.org/10.1128/aem.02301-14openalex-snapshot
Microbial Synthesis of the Forskolin Precursor Manoyl Oxide in an Enantiomerically Pure Form
inferred← citeshttps://doi.org/10.1128/jb.01031-13openalex-snapshot
Functional Conservation of the Capacity for ent-Kaurene Biosynthesis and an Associated Operon in Certain Rhizobia
inferred← citeshttps://doi.org/10.1177/1934578x241252505openalex-snapshot
Absolute Configuration and Cytotoxicity of a New Vouacapane Diterpenoid from Coulteria velutina
inferred← citeshttps://doi.org/10.1186/s12864-015-1864-yopenalex-snapshot
Andrographis paniculata transcriptome provides molecular insights into tissue-specific accumulation of medicinal diterpenes
inferred← citeshttps://doi.org/10.1186/s12870-020-2293-xopenalex-snapshot
Nerylneryl diphosphate is the precursor of serrulatane, viscidane and cembrane-type diterpenoids in Eremophila species
inferred← citeshttps://doi.org/10.31274/etd-180810-1618openalex-snapshot
On the biosynthesis of labdane-related diterpenoids by class I synthases and P450s: a
inferred← citeshttps://doi.org/10.31274/etd-180810-2465openalex-snapshot
Investigating the evolution of cytochromes P450 involved in GA biosynthesis
inferred← citeshttps://doi.org/10.31274/etd-180810-3614openalex-snapshot
Structure and function of class I diterpene synthase
inferred← citeshttps://doi.org/10.31274/rtd-180813-16986openalex-snapshot
Investigating reactions catalyzed by terpene synthases in a novel model system
inferred← citeshttps://doi.org/10.31274/td-20240329-459openalex-snapshot
Investigation of cytochrome P450s in the biosynthesis of rice phytoalexins
inferred← citeshttps://doi.org/10.31274/td-20240329-820openalex-snapshot
Transcending eons; evolutionary and mechanistic insight into plant Class I Diterpene synthases
inferred← citeshttps://doi.org/10.3389/ffunb.2022.869823openalex-snapshot
Diterpene Biosynthesis in Rice Blast Fungus Magnaporthe
inferred← citeshttps://doi.org/10.3389/fpls.2016.01761openalex-snapshot
Identification of a Dolabellane Type Diterpene Synthase and other Root-Expressed Diterpene Synthases in Arabidopsis
inferred← citeshttps://doi.org/10.3389/fpls.2016.01765openalex-snapshot
Extending a Single Residue Switch for Abbreviating Catalysis in Plant ent-Kaurene Synthases
inferred← citeshttps://doi.org/10.3389/fpls.2026.1943006openalex-snapshot
Functional identification of two cytochrome P450 enzymes involved in diterpenoid oxidation in Ginkgo biloba
inferred← citeshttps://doi.org/10.3390/biom11060898openalex-snapshot
A Sesquiterpene Synthase from the Endophytic Fungus Serendipita indica Catalyzes Formation of Viridiflorol
inferred← citeshttps://doi.org/10.3390/crops5030033openalex-snapshot
The Composition of Essential Oils and the Content of Saponins in Different Parts of Gilia capitata Sims
inferred← citeshttps://doi.org/10.3390/genes10060441openalex-snapshot
A Wheat β-Patchoulene Synthase Confers Resistance against Herbivory in Transgenic Arabidopsis
inferred← citeshttps://doi.org/10.3390/microorganisms12030500openalex-snapshot
Engineering Terpene Production Pathways in Methylobacterium extorquens AM1
inferred← citeshttps://doi.org/10.3390/molecules23112952openalex-snapshot
Transcriptomic Insight into Terpenoid Biosynthesis and Functional Characterization of Three Diterpene Synthases in Scutellaria barbata
inferred← citeshttps://doi.org/10.3390/molecules29010212openalex-snapshot
Evaluation of Anti-Trypanosoma cruzi Activity of Chemical Constituents from Baccharis sphenophylla Isolated Using High-Performance Countercurrent Chromatography
inferred← citeshttps://doi.org/10.3390/plants12010069openalex-snapshot
Functional Characterization of Three Diterpene Synthases Responsible for Tetracyclic Diterpene Biosynthesis in Scoparia dulcis
inferred← citeshttps://doi.org/10.3390/plants9081018openalex-snapshot
Identification of Three Monofunctional Diterpene Synthases with Specific Enzyme Activities Expressed during Heartwood Formation in Western Redcedar (Thuja plicata) Trees
inferred← citeshttps://doi.org/10.3791/59992openalex-snapshot
A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
inferred← citeshttps://doi.org/10.3791/59992-vopenalex-snapshot
A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
inferred← citeshttps://doi.org/10.48130/bpr-2021-0007openalex-snapshot
Identification and functional characterization of ent-kaurene synthase gene in Ilex latifolia
inferred← citeshttps://doi.org/10.5511/plantbiotechnology.14.1003aopenalex-snapshot
Microbial production of plant specialized metabolites
inferred← citeshttps://doi.org/10.70675/af79a9cfz907bz45d6z8aadz0c40245fd5bbopenalex-snapshot
Développement d’une plateforme microbienne pour la biosynthèse de diterpènes et la caractérisation de diterpènes synthases : application au cas de l’ent-kaurène
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