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Spiro-Ring Formation is Catalyzed by a Multifunctional Dioxygenase in Austinol Biosynthesis

https://doi.org/10.1021/ja405518u
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cbic.201200124openalex-snapshot
Identification of a Key Prenyltransferase Involved in Biosynthesis of the Most Abundant Fungal Meroterpenoids Derived from 3,5‐Dimethylorsellinic Acid.
inferredcites →https://doi.org/10.1002/cbic.201200369openalex-snapshot
Terretonin Biosynthesis Requires Methylation as Essential Step for Cyclization
inferredcites →https://doi.org/10.1016/j.febslet.2006.02.008openalex-snapshot
Four gene products are required for the fungal synthesis of the indole‐diterpene, paspaline
inferredcites →https://doi.org/10.1016/s0009-8981(97)00259-3openalex-snapshot
Characterization of phytanoyl-Coenzyme A hydroxylase in human liver and activity measurements in patients with peroxisomal disorders
inferredcites →https://doi.org/10.1016/s0031-9422(02)00379-5openalex-snapshot
Meroterpenes from Penicillium sp found in association with Melia azedarach
inferredcites →https://doi.org/10.1016/s0040-4020(01)85511-3openalex-snapshot
Limonoids from Carapa grandiflora (meliaceae)
inferredcites →https://doi.org/10.1021/ja00105a078openalex-snapshot
Relative and Absolute Stereochemistry of Pyripyropene A, A Potent, Bioavailable Inhibitor of Acyl-CoA:Cholesterol Acyltransferase (ACAT)
inferredcites →https://doi.org/10.1021/ja004025+openalex-snapshot
Spectroscopic Studies of Substrate Interactions with Clavaminate Synthase 2, a Multifunctional α-KG-Dependent Non-Heme Iron Enzyme: Correlation with Mechanisms and Reactivities
inferredcites →https://doi.org/10.1021/ja209809topenalex-snapshot
Two Separate Gene Clusters Encode the Biosynthetic Pathway for the Meroterpenoids Austinol and Dehydroaustinol in Aspergillus nidulans
inferredcites →https://doi.org/10.1021/ja3116636openalex-snapshot
Reconstitution of Biosynthetic Machinery for Indole-Diterpene Paxilline in Aspergillus oryzae
inferredcites →https://doi.org/10.1021/ja961897wopenalex-snapshot
Enzymatic Formation of Isochamigrene, a Novel Sesquiterpene, by Alteration of the Aspartate-Rich Region of Trichodiene Synthase
inferredcites →https://doi.org/10.1021/np2003066openalex-snapshot
Berkeleyones and Related Meroterpenes from a Deep Water Acid Mine Waste Fungus That Inhibit the Production of Interleukin 1-β from Induced Inflammasomes
inferredcites →https://doi.org/10.1021/ol302682zopenalex-snapshot
Molecular Genetic Characterization of a Cluster in A. terreus for Biosynthesis of the Meroterpenoid Terretonin
inferredcites →https://doi.org/10.1038/29575openalex-snapshot
Structure of a cephalosporin synthase
inferredcites →https://doi.org/10.1038/ja.2010.162openalex-snapshot
Characterization of two cytochrome P450 monooxygenase genes of the pyripyropene biosynthetic gene cluster from Penicillium coprobium
inferredcites →https://doi.org/10.1038/nchem.764openalex-snapshot
Reconstitution of a fungal meroterpenoid biosynthesis reveals the involvement of a novel family of terpene cyclases
inferredcites →https://doi.org/10.1038/nchembio.71openalex-snapshot
Versatility of biological non-heme Fe(II) centers in oxygen activation reactions
inferredcites →https://doi.org/10.1039/b820413fopenalex-snapshot
Meroterpenoids produced by fungi
inferredcites →https://doi.org/10.1039/c3976000270aopenalex-snapshot
Isolation of C25 polyisoprenoids from Aspergillus sp: crystal structure of andibenin
inferredcites →https://doi.org/10.1039/c39810000914openalex-snapshot
Anditomin, a new C25 metabolite from Aspergillus variecolor
inferredcites →https://doi.org/10.1039/j39660001374openalex-snapshot
The chemistry of triterpenes and related compounds. Part XLV. The acid-catalysed rearrangements of the 5α,6α-diols and 5,6-epoxides of some 4,4-dimethylsteroids
inferredcites →https://doi.org/10.1039/p19790000775openalex-snapshot
Acid-catalysed ring contraction of steroidal 4β,5β-epoxy-1-en-3-ones
inferredcites →https://doi.org/10.1039/p19790002118openalex-snapshot
Studies on fungal metabolites. Part 1. The structures of andibenins-A and -C, and andilesins-A, -B, and -C, meroterpenoids from Aspergillus variecolor
inferredcites →https://doi.org/10.1039/p19890000807openalex-snapshot
Studies on the biosynthesis of the mycotoxin austin, a meroterpenoid metabolite of Aspergillus ustus
inferredcites →https://doi.org/10.1073/pnas.1201469109openalex-snapshot
Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis
inferredcites →https://doi.org/10.1074/jbc.m701626200openalex-snapshot
Defining Paxilline Biosynthesis in Penicillium paxilli
inferredcites →https://doi.org/10.1111/j.1574-6968.2011.02327.xopenalex-snapshot
A genome-wide polyketide synthase deletion library uncovers novel genetic links to polyketides and meroterpenoids in Aspergillus nidulans
inferredcites →https://doi.org/10.1271/bbb.68.656openalex-snapshot
Adenine Auxotrophic Mutants ofAspergillus oryzae: Development of a Novel Transformation System with Triple Auxotrophic Hosts
inferredcites →https://doi.org/10.7164/antibiotics.49.1278openalex-snapshot
Andrastin D, Novel Protein Farnesyltransferase Inhibitor Produced by Penicillium sp. FO-3929.
inferredcites →https://doi.org/10.7164/antibiotics.49.418openalex-snapshot
Andrastins A-C, New Protein Farnesyltransferase Inbibitors Produced by Penicillium sp. FO-3929. II. Structure Elucidation and Biosynthesis.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Asperanstinoids A–E: Undescribed 3,5-dimethylorsellinic acid-based meroterpenoids from Aspergillus calidoustus
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Recent studies on terpenoids in Aspergillus fungi: Chemical diversity, biosynthesis, and bioactivity
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Fe(II) /(Alpha)Ketoglutarate‐Dependent Dioxygenase PrhA
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Asymmetric α‐Hydroxylation of β‐Indanone Esters and β‐Indanone Amides Catalyzed by C‐2′ Substituted Cinchona Alkaloid Derivatives
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Palladium‐Catalyzed Tandem Reaction of Alkyne‐Based Aryl Iodides and Salicyl N‐Tosylhydrazones to Construct the Spiro[benzofuran‐3,2′‐chromene] Skeleton
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Advances in α‐Hydroxylation of β‐Dicarbonyl Compounds
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Non‐Heme Dioxygenase Catalyzes Atypical Oxidations of 6,7‐Bicyclic Systems To Form the 6,6‐Quinolone Core of Viridicatin‐Type Fungal Alkaloids
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Reconstitution of Biosynthetic Machinery for the Synthesis of the Highly Elaborated Indole Diterpene Penitrem
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Traversing Biosynthetic Carbocation Landscapes in the Total Synthesis of Andrastin and Terretonin Meroterpenes
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The Biosynthesis of Norsesquiterpene Aculenes Requires Three Cytochrome P450 Enzymes to Catalyze a Stepwise Demethylation Process
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Characterization of Multifunctional and Non‐stereoselective Oxidoreductase RubE7/IstO, Expanding the Functional Diversity of the Flavoenzyme Superfamily
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Correspondence on “Structural Insight into the Catalytic Mechanism of the Endoperoxide Synthase FtmOx1”
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Non‐Heme Dioxygenase Catalyzes Atypical Oxidations of 6,7‐Bicyclic Systems To Form the 6,6‐Quinolone Core of Viridicatin‐Type Fungal Alkaloids
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Reconstitution of Biosynthetic Machinery for the Synthesis of the Highly Elaborated Indole Diterpene Penitrem
inferred← citeshttps://doi.org/10.1002/anie.201705654openalex-snapshot
Traversing Biosynthetic Carbocation Landscapes in the Total Synthesis of Andrastin and Terretonin Meroterpenes
inferred← citeshttps://doi.org/10.1002/anie.201910200openalex-snapshot
The Biosynthesis of Norsesquiterpene Aculenes Requires Three Cytochrome P450 Enzymes to Catalyze a Stepwise Demethylation Process
inferred← citeshttps://doi.org/10.1002/anie.202200189openalex-snapshot
Characterization of Multifunctional and Non‐stereoselective Oxidoreductase RubE7/IstO, Expanding the Functional Diversity of the Flavoenzyme Superfamily
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Correspondence on “Structural Insight into the Catalytic Mechanism of the Endoperoxide Synthase FtmOx1”
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Construction of Bridged Polycyclic Systems by Polyene Cyclization
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Bifunctional Ammonium Salt Catalyzed Asymmetric α‐Hydroxylation of β‐Ketoesters by Simultaneous Resolution of Oxaziridines
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3,5‐Dimethylorsellinic Acid Derived Meroterpenoids from Eupenicillium sp. 6A‐9, a Fungus Isolated from the Marine Sponge Plakortis simplex
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Bioactive Austin Meroterpenes from the Mangrove-Derived Fungus Penicillium sp. TGM112
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Biosynthesis of unique natural product scaffolds by Fe(II)/αKG-dependent oxygenases
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Oxidative Modification Enzymes in Polyketide Biosynthetic Pathways
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Fungal Meroterpenoids
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Olefin, Nitrile and Isonitrile Installation Catalyzed by Metalloenzymes
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Drimane-Related Merosesquiterpenoids, a Promising Library of Metabolites for Drug Development
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Non-heme iron enzyme-catalyzed complex transformations
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Functional analysis of an α-ketoglutarate-dependent non-heme iron oxygenase in fungal meroterpenoid biosynthesis
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Activation of an unconventional meroterpenoid gene cluster in Neosartorya glabra leads to the production of new berkeleyacetals
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Late-stage cascade of oxidation reactions during the biosynthesis of oxalicine B in Penicillium oxalicum
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Complete biosynthesis of phenylspirodrimanes with unclustered genes in Stachybotrys chartarum
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Metabolism of steroidal lactones by the fungus Corynespora cassiicola CBS 161.60 results in a mechanistically unique intramolecular ring-D cyclization resulting in C-14 spiro-lactones
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Ferrous iron and α-ketoglutarate-dependent dioxygenases in the biosynthesis of microbial natural products
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Recent advances in reconstructing microbial secondary metabolites biosynthesis in Aspergillus spp.
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Unusual chemistries in fungal meroterpenoid biosynthesis
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Enzymology and biosynthesis of the orsellinic acid derived medicinal meroterpenoids
inferred← citeshttps://doi.org/10.1016/j.copbio.2022.102763openalex-snapshot
Harnessing Fe(II)/α-ketoglutarate-dependent oxygenases for structural diversification of fungal meroterpenoids
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Meroterpenoids produced by fungi: Occurrence, structural diversity, biological activities, and their molecular targets
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Four new hybrid polyketide-terpenoid metabolites from the Penicillium sp. SYPF7381 in the rhizosphere soil of Pulsatilla chinensis
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DMOA-derived polycyclic meroterpenoids with antiviral activities from the deep-sea-derived fungus Penicillium pancosmium A6A
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Methylhydrazine-induced enantioselective α-hydroxylation of β-keto esters with molecular oxygen catalyzed by hydroquinine
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Highly chemo- and enantioselective vinylogous aldol/cyclization cascade reaction to construct chiral 5,6-dihydropyran-2-ones
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DMOA-based meroterpenoids with diverse scaffolds from the sponge-associated fungus Penicillium brasilianum
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Enzymatic formation of endoperoxide by Fe(II)/α-KG-dependent dioxygenase NvfI: Insight into substrate-assisted activation of the distant C–H bond and incorporation of two oxygen molecules
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Tryptophan-Centric Bioinformatics Identifies New Lasso Peptide Modifications
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Oxidative Cyclization in Natural Product Biosynthesis
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Formation and Cleavage of C–C Bonds by Enzymatic Oxidation–Reduction Reactions
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Structurally Diverse Meroterpenoids from a Marine-Derived Aspergillus sp. Fungus
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A Series of Cinchona-Derived N-Oxide Phase-Transfer Catalysts: Application to the Photo-Organocatalytic Enantioselective α-Hydroxylation of β-Dicarbonyl Compounds
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Oxidative Ring Contraction by a Multifunctional Dioxygenase Generates the Core Cycloocatadiene in the Biosynthesis of Fungal Dimeric Anhydride Zopfiellin
inferred← citeshttps://doi.org/10.1021/acs.orglett.0c01358openalex-snapshot
Structural Diversification of Andiconin-Derived Natural Products by α-Ketoglutarate-Dependent Dioxygenases
inferred← citeshttps://doi.org/10.1021/acs.orglett.1c00330openalex-snapshot
An Enzyme-Mediated Aza-Michael Addition Is Involved in the Biosynthesis of an Imidazoyl Hybrid Product of Conidiogenone B
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Genome Mining-Driven Discovery of 5-Methylorsellinate-Derived Meroterpenoids from Aspergillus funiculosus
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A Multifunctional Cytochrome P450 and a Meroterpenoid Cyclase in the Biosynthesis of Fungal Meroterpenoid Atlantinone B
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Biosynthesis of Piperazine-Derived Diazabicyclic Alkaloids Involves a Nonribosomal Peptide Synthetase and Subsequent Tailoring by a Multifunctional Cytochrome P450 Enzyme
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Cytochrome P450 for Citreohybridonol Synthesis: Oxidative Derivatization of the Andrastin Scaffold
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Mining of Meroterpenoids with Anti-inflammatory Activity from the Mangrove Endophytic Fungus Talaromyces sp. JNQQJ-4 by Genome Analysis and Molecular Network Strategy
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Dimericbiscognienyne A: A Meroterpenoid Dimer from Biscogniauxia sp. with New Skeleton and Its Activity
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Combinatorial Biosynthesis of (+)-Daurichromenic Acid and Its Halogenated Analogue
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Simpterpenoid A, a Meroterpenoid with a Highly Functionalized Cyclohexadiene Moiety Featuring gem-Propane-1,2-dione and Methylformate Groups, from the Mangrove-Derived Penicillium simplicissimum MA-332
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Elucidation and Heterologous Reconstitution of Chrodrimanin B Biosynthesis
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Aspermeroterpenes A–C: Three Meroterpenoids from the Marine-Derived Fungus Aspergillus terreus GZU-31-1
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Discovery of Noncanonical Iron and 2-Oxoglutarate Dependent Enzymes Involved in C–C and C–N Bond Formation in Biosynthetic Pathways
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Divergent Biosynthesis of Fungal Dioxafenestrane Sesquiterpenes by the Cooperation of Distinctive Baeyer–Villiger Monooxygenases and α-Ketoglutarate-Dependent Dioxygenases
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Substrate-Dependent Mechanism Switch in the Desaturation Reactions of the Mononuclear Nonheme Iron Enzyme PtlD
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Coordinated and Iterative Enzyme Catalysis in Fungal Polyketide Biosynthesis
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Discovery of an Extended Austinoid Biosynthetic Pathway in Aspergillus calidoustus
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Rewiring of the Austinoid Biosynthetic Pathway in Filamentous Fungi
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Identification of Marine-Derived Compounds with Potent Antiviral Activity in a Recombinant HBV cccDNA Cell Model
inferred← citeshttps://doi.org/10.1021/acsomega.5c12080openalex-snapshot
Search for Inhibitors against Inflammatory Responses of Microglia in a Meroterpenoid Library Constructed by Synthetic–Biological Manipulation of Biosynthetic Pathways
inferred← citeshttps://doi.org/10.1021/ar500242copenalex-snapshot
Highly Selective but Multifunctional Oxygenases in Secondary Metabolism
inferred← citeshttps://doi.org/10.1021/ja500881eopenalex-snapshot
Generation of Complexity in Fungal Terpene Biosynthesis: Discovery of a Multifunctional Cytochrome P450 in the Fumagillin Pathway
inferred← citeshttps://doi.org/10.1021/ja508127qopenalex-snapshot
Complete Biosynthetic Pathway of Anditomin: Nature’s Sophisticated Synthetic Route to a Complex Fungal Meroterpenoid
inferred← citeshttps://doi.org/10.1021/jacs.0c12352openalex-snapshot
Biosynthesis of the Immunosuppressant (−)-FR901483
inferred← citeshttps://doi.org/10.1021/jacs.1c11548openalex-snapshot
Heterodimeric Non-heme Iron Enzymes in Fungal Meroterpenoid Biosynthesis
inferred← citeshttps://doi.org/10.1021/jacs.3c11772openalex-snapshot
Deciphering Deoxynybomycin Biosynthesis Reveals Fe(II)/α-Ketoglutarate-Dependent Dioxygenase-Catalyzed Oxazoline Ring Formation and Decomposition
inferred← citeshttps://doi.org/10.1021/jacs.4c09298openalex-snapshot
Target Discovery of Dhilirane-Type Meroterpenoids by Biosynthesis Guidance and Tailoring Enzyme Catalysis
inferred← citeshttps://doi.org/10.1021/jacs.4c15205openalex-snapshot
Total Synthesis of DMOA-Derived Meroterpenoids: Achieving Selectivity in the Synthesis of (+)-Berkeleyacetal D and (+)-Peniciacetal I
inferred← citeshttps://doi.org/10.1021/jacs.5b00570openalex-snapshot
Uncovering the Unusual D-Ring Construction in Terretonin Biosynthesis by Collaboration of a Multifunctional Cytochrome P450 and a Unique Isomerase
inferred← citeshttps://doi.org/10.1021/jacs.5b07816openalex-snapshot
Efficient Biosynthesis of Fungal Polyketides Containing the Dioxabicyclo-octane Ring System
inferred← citeshttps://doi.org/10.1021/jacs.5b08958openalex-snapshot
Total Synthesis of Atisane-Type Diterpenoids: Application of Diels–Alder Cycloadditions of Podocarpane-Type Unmasked ortho-Benzoquinones
inferred← citeshttps://doi.org/10.1021/jacs.5c11241openalex-snapshot
Radical Ring Expansion Catalyzed by an α-Ketoglutarate-Dependent Dioxygenase in the Biosynthesis of Tropolones
inferred← citeshttps://doi.org/10.1021/jacs.6b08424openalex-snapshot
Discovery of Key Dioxygenases that Diverged the Paraherquonin and Acetoxydehydroaustin Pathways in Penicillium brasilianum
inferred← citeshttps://doi.org/10.1021/jacs.6b10397openalex-snapshot
Annulative Methods Enable a Total Synthesis of the Complex Meroterpene Berkeleyone A
inferred← citeshttps://doi.org/10.1021/jacs.6b12246openalex-snapshot
Polycyclic Ketone Monooxygenase from the Thermophilic Fungus Thermothelomyces thermophila : A Structurally Distinct Biocatalyst for Bulky Substrates
inferred← citeshttps://doi.org/10.1021/jacs.6b12914openalex-snapshot
Total Synthesis of (±)-Berkeleyone A
inferred← citeshttps://doi.org/10.1021/jacsau.2c00248openalex-snapshot
Dissecting the Mechanism of the Nonheme Iron Endoperoxidase FtmOx1 Using Substrate Analogues
inferred← citeshttps://doi.org/10.1038/ja.2016.54openalex-snapshot
New natural products isolated from Metarhizium robertsii ARSEF 23 by chemical screening and identification of the gene cluster through engineered biosynthesis in Aspergillus nidulans A1145
inferred← citeshttps://doi.org/10.1038/nchembio.2443openalex-snapshot
Molecular basis for the unusual ring reconstruction in fungal meroterpenoid biogenesis
inferred← citeshttps://doi.org/10.1038/s41429-018-0034-2openalex-snapshot
Furanoaustinol and 7-acetoxydehydroaustinol: new meroterpenoids from a marine-derived fungal strain Penicillium sp. SF-5497
inferred← citeshttps://doi.org/10.1038/s41467-017-02371-wopenalex-snapshot
Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis
inferred← citeshttps://doi.org/10.1038/s41467-018-04983-2openalex-snapshot
Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation
inferred← citeshttps://doi.org/10.1038/s41467-021-24685-6openalex-snapshot
Molecular insights into the endoperoxide formation by Fe(II)/α-KG-dependent oxygenase NvfI
inferred← citeshttps://doi.org/10.1039/c3np70077aopenalex-snapshot
Transition metal-promoted biomimetic steps in total syntheses
inferred← citeshttps://doi.org/10.1039/c3np90029kopenalex-snapshot
Hot off the Press
inferred← citeshttps://doi.org/10.1039/c4np00059eopenalex-snapshot
Oxidative rearrangements during fungal biosynthesis
inferred← citeshttps://doi.org/10.1039/c4np00065jopenalex-snapshot
Fungal polyketide biosynthesis – a personal perspective
inferred← citeshttps://doi.org/10.1039/c5np00090dopenalex-snapshot
Biosynthesis of fungal meroterpenoids
inferred← citeshttps://doi.org/10.1039/c6qo00018eopenalex-snapshot
Direct construction of chiral quaternary dihydropyranones through highly enantioselective organocatalytic hetero-Diels–Alder reactions of olefinic azlactones
inferred← citeshttps://doi.org/10.1039/c7cc03303fopenalex-snapshot
Genetic and chemical characterisation of the cornexistin pathway provides further insight into maleidride biosynthesis
inferred← citeshttps://doi.org/10.1039/c7np00055copenalex-snapshot
Unique chemistry of non-heme iron enzymes in fungal biosynthetic pathways
inferred← citeshttps://doi.org/10.1039/c7np00067gopenalex-snapshot
Recent examples of α-ketoglutarate-dependent mononuclear non-haem iron enzymes in natural product biosyntheses
inferred← citeshttps://doi.org/10.1039/c9cp03565fopenalex-snapshot
Catalytic mechanism of the PrhA (V150L/A232S) double mutant involved in the fungal meroterpenoid biosynthetic pathway: a QM/MM study
inferred← citeshttps://doi.org/10.1039/d0np00056fopenalex-snapshot
Chemistry of fungal meroterpenoid cyclases
inferred← citeshttps://doi.org/10.1039/d2cc00736copenalex-snapshot
Structure-based redesign of Fe( ii )/2-oxoglutarate-dependent oxygenase AndA to catalyze spiro-ring formation
inferred← citeshttps://doi.org/10.1039/d2np00014hopenalex-snapshot
Structure-based engineering of α-ketoglutarate dependent oxygenases in fungal meroterpenoid biosynthesis
inferred← citeshttps://doi.org/10.1039/d2qo00055eopenalex-snapshot
Biocatalytic and chemical derivatization of the fungal meroditerpenoid chevalone E
inferred← citeshttps://doi.org/10.1039/d2sc02994dopenalex-snapshot
Discovery of branching meroterpenoid biosynthetic pathways in Aspergillus insuetus : involvement of two terpene cyclases with distinct cyclization modes
inferred← citeshttps://doi.org/10.1039/d3sc06001bopenalex-snapshot
Global genome mining-driven discovery of an unusual biosynthetic logic for fungal polyketide–terpenoid hybrids
inferred← citeshttps://doi.org/10.1039/d4cb00186aopenalex-snapshot
Characterization of the Baeyer–Villiger monooxygenase in the pathway of the bacterial pyrrolizidine alkaloids, legonmycins
inferred← citeshttps://doi.org/10.1039/d4cy01077aopenalex-snapshot
Characterizing Y224 conformational flexibility in FtmOx1-catalysis using 19 F NMR spectroscopy
inferred← citeshttps://doi.org/10.1098/rstb.2022.0037openalex-snapshot
Orthoester formation in fungal meroterpenoid austalide F biosynthesis
inferred← citeshttps://doi.org/10.1111/1462-2920.14333openalex-snapshot
Enfumafungin synthase represents a novel lineage of fungal triterpene cyclases
inferred← citeshttps://doi.org/10.1111/febs.15129openalex-snapshot
A pharmaceutical model for the molecular evolution of microbial natural products
inferred← citeshttps://doi.org/10.1186/s40694-022-00135-wopenalex-snapshot
Branching and converging pathways in fungal natural product biosynthesis
inferred← citeshttps://doi.org/10.1248/cpb.c20-00360openalex-snapshot
Nonheme Iron- and 2-Oxoglutarate-Dependent Dioxygenases in Fungal Meroterpenoid Biosynthesis
inferred← citeshttps://doi.org/10.1248/cpb.c25-00652openalex-snapshot
Structure-Guided Engineering of 2-Oxoglutarate-Dependent Oxygenases: Principles, Case Studies, and Emerging Opportunities
inferred← citeshttps://doi.org/10.20307/nps.2018.24.4.253openalex-snapshot
New Meroterpenoids from a Penicillium sp. Fungus
inferred← citeshttps://doi.org/10.2210/pdb5ybr/pdbopenalex-snapshot
Fe(II)/(alpha)ketoglutarate-dependent dioxygenase PrhA-V150L/A232S in complex with preaustinoid A3
inferred← citeshttps://doi.org/10.31038/jppr.2020324openalex-snapshot
Cytotoxic Meroterpenes: A Review
inferred← citeshttps://doi.org/10.3389/fchem.2018.00314openalex-snapshot
Brasilianoids A–F, New Meroterpenoids From the Sponge-Associated Fungus Penicillium brasilianum
inferred← citeshttps://doi.org/10.3389/fpls.2024.1435440openalex-snapshot
Endophytic bacteria with allelopathic potential regulate gene expression and metabolite production in host Casuarina equisetifolia
inferred← citeshttps://doi.org/10.3390/catal13030581openalex-snapshot
Multifunctional Enzymes in Microbial Secondary Metabolic Processes
inferred← citeshttps://doi.org/10.3390/jof10020162openalex-snapshot
Austin-Type Meroterpenoids from Fungi Reported in the Last Five Decades: A Review
inferred← citeshttps://doi.org/10.3390/jof8030320openalex-snapshot
Biosynthesis of Fungal Natural Products Involving Two Separate Pathway Crosstalk
inferred← citeshttps://doi.org/10.3390/md19040189openalex-snapshot
New Andrastin-Type Meroterpenoids from the Marine-Derived Fungus Penicillium sp.
inferred← citeshttps://doi.org/10.3390/md20060404openalex-snapshot
Deep-Sea Natural Products from Extreme Environments: Cold Seeps and Hydrothermal Vents
inferred← citeshttps://doi.org/10.3390/toxins10120521openalex-snapshot
Alternative Splicing of the Aflatoxin-Associated Baeyer–Villiger Monooxygenase from Aspergillus flavus: Characterisation of MoxY Isoforms
inferred← citeshttps://doi.org/10.3762/bjoc.20.50openalex-snapshot
Recent developments in the engineered biosynthesis of fungal meroterpenoids
inferred← citeshttps://doi.org/10.3762/bjoc.22.21openalex-snapshot
Ring contraction and ring expansion reactions in terpenoid biosynthesis and their application to total synthesis
inferred← citeshttps://doi.org/10.3987/rev-15-830openalex-snapshot
Total Biosynthesis of Fungal Indole Diterpenes Using Cell Factories
inferred← citeshttps://doi.org/10.5059/yukigoseikyokaishi.72.548openalex-snapshot
Synthesis of Natural Products with Biosynthetic Machinery
inferred← citeshttps://doi.org/10.53365/nrfhh/206017openalex-snapshot
Unraveling the Biosynthetic Gene Clusters and In Silico Insights into Meroterpenoids from the Indonesian Marine Sponge Endosymbiont Fungus Aspergillus nidulans
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