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Structural Basis for the Structure−Activity Relationships of Peroxisome Proliferator-Activated Receptor Agonists

https://doi.org/10.1021/jm060663c
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Diabetes: Assessing the pipeline
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Diabetes: New challenges for the control of disease globalisation
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Mo-P1:16 The APOB/APOA1 ratio as a determinant of cardiovascular risk at LDL cholesterol (LDL-C) therapeutic target levels
inferredcites →https://doi.org/10.1021/jm0506930openalex-snapshot
Novel Indole-Based Peroxisome Proliferator-Activated Receptor Agonists: Design, SAR, Structural Biology, and Biological Activities
inferredcites →https://doi.org/10.1038/25931openalex-snapshot
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
inferredcites →https://doi.org/10.2174/0929867033368295openalex-snapshot
Recent Advances in Peroxisome Proliferator-Activated Receptor Science
inferredcites →https://doi.org/10.2337/diabetes.54.8.2460openalex-snapshot
Therapeutic Roles of Peroxisome Proliferator–Activated Receptor Agonists

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Multireceptor Analysis for Evaluating the Antidiabetic Efficacy of Karanjin: A Computational Approach
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Bioassay‐guided purification and identification of PPARα/γ agonists from Chlorella sorokiniana
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Chapter 5.2 Five-membered ring systems: pyrroles and benzo analogs
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Substituent Diversity-Directed Synthesis of Indole Derivatives
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Design and Structural Analysis of Novel Pharmacophores for Potent and Selective Peroxisome Proliferator-activated Receptor γ Agonists
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Synthesis of novel PPARα/γ dual agonists as potential drugs for the treatment of the metabolic syndrome and diabetes type II designed using a new de novo design program protobuild
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Identification of PPARγ Agonists from Natural Sources Using Different In Silico Approaches
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Combined Simulation and Mutagenesis Analyses Reveal the Involvement of Key Residues for Peroxisome Proliferator-activated Receptorα Helix 12 Dynamic Behavior
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Phytochemicals as Modulators of PPARs and RXRs
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Virtual Screening as a Technique for PPAR Modulator Discovery
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SAR and Computer-Aided Drug Design Approaches in the Discovery of Peroxisome Proliferator-Activated Receptor γ Activators: A Perspective
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Dietary α-Eleostearic Acid Ameliorates Experimental Inflammatory Bowel Disease in Mice by Activating Peroxisome Proliferator-Activated Receptor-γ
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Molecular approaches in identification of cancerous mutations and protein families
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