On the public citation graph

Enhancing Macrocyclic Diterpenes as Multidrug-Resistance Reversers: Structure–Activity Studies on Jolkinol D Derivatives

https://doi.org/10.1021/jm301441w
0 signed · 97 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.
Claim with ORCID
Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.
See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cyto.990090617openalex-snapshot
Modified histogram subtraction technique for analysis of flow cytometry data
inferredcites →https://doi.org/10.1002/ijc.2910490427openalex-snapshot
Induction of multiple‐drug resistance during anti‐neoplastic chemotherapy in vitro
inferredcites →https://doi.org/10.1002/minf.201000017openalex-snapshot
Impact of the Recent Mouse P‐Glycoprotein Structure for Structure‐Based Ligand Design
inferredcites →https://doi.org/10.1007/s10863-007-9115-9openalex-snapshot
Genomics and the mechanism of P-glycoprotein (ABCB1)
inferredcites →https://doi.org/10.1016/j.bmc.2007.05.036openalex-snapshot
Structure–activity relationships of novel N-acyloxy-1,4-dihydropyridines as P-glycoprotein inhibitors
inferredcites →https://doi.org/10.1016/j.bmc.2008.08.071openalex-snapshot
Synergistic interaction between p-glycoprotein modulators and epirubicine on resistant cancer cells
inferredcites →https://doi.org/10.1016/j.febslet.2006.02.020openalex-snapshot
Mechanisms and strategies to overcome multiple drug resistance in cancer
inferredcites →https://doi.org/10.1016/s0040-4039(00)93940-6openalex-snapshot
The structure of new lathyrane diterpenes, jolkinols a, b, c, and d, from Euphorbia jolkini boiss.
inferredcites →https://doi.org/10.1016/s0959-8049(03)00619-1openalex-snapshot
Drug resistance reversal—are we getting closer?
inferredcites →https://doi.org/10.1021/ci200145popenalex-snapshot
Toward a Better Pharmacophore Description of P-Glycoprotein Modulators, Based on Macrocyclic Diterpenes fromEuphorbiaSpecies
inferredcites →https://doi.org/10.1021/ct300083mopenalex-snapshot
Insights on P-Glycoprotein’s Efflux Mechanism Obtained by Molecular Dynamics Simulations
inferredcites →https://doi.org/10.1021/jm030183aopenalex-snapshot
Multidrug Resistance Reversal Agents
inferredcites →https://doi.org/10.1021/np060046ropenalex-snapshot
Euphoportlandols A and B, Tetracylic Diterpene Polyesters from Euphorbia p ortlandica and Their Anti-MDR Effects in Cancer Cells
inferredcites →https://doi.org/10.1038/nrc706openalex-snapshot
Multidrug resistance in cancer: role of ATP–dependent transporters
inferredcites →https://doi.org/10.1038/sj.onc.1206948openalex-snapshot
P-glycoprotein: from genomics to mechanism
inferredcites →https://doi.org/10.1055/s-2004-815454openalex-snapshot
Rearranged Jatrophane-Type Diterpenes fromEuphorbiaSpecies. Evaluation of their Effects on the Reversal of Multidrug Resistance
inferredcites →https://doi.org/10.1055/s-2004-815464openalex-snapshot
Pubescenes, Jatrophane Diterpenes, fromEuphorbia pubescens,with Multidrug Resistance Reversing Activity on Mouse Lymphoma Cells
inferredcites →https://doi.org/10.1055/s-2004-827231openalex-snapshot
A New Sesquiterpene-Coumarin Ether and a New Abietane Diterpene and their Effects as Inhibitors of P-Glycoprotein
inferredcites →https://doi.org/10.1055/s-2007-993765openalex-snapshot
Three New Jatrophane Polyesters and Antiproliferative Constituents from Euphorbia tuckeyana
inferredcites →https://doi.org/10.1073/pnas.85.12.4486openalex-snapshot
A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells.
inferredcites →https://doi.org/10.1073/pnas.97.6.2515openalex-snapshot
Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein
inferredcites →https://doi.org/10.1080/10611860310001648248openalex-snapshot
Classification Analysis of P-Glycoprotein Substrate Specificity
inferredcites →https://doi.org/10.1093/oso/9780195171792.001.0001openalex-snapshot
Fitting Models to Biological Data Using Linear and Nonlinear Regression
inferredcites →https://doi.org/10.1126/science.1168750openalex-snapshot
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
inferredcites →https://doi.org/10.1146/annurev.pharmtox.39.1.361openalex-snapshot
BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTER
inferredcites →https://doi.org/10.1152/physrev.00037.2005openalex-snapshot
Human Multidrug Resistance ABCB and ABCG Transporters: Participation in a Chemoimmunity Defense System
inferredcites →https://doi.org/10.1158/0008-5472.can-09-1947openalex-snapshot
Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
inferredcites →https://doi.org/10.1172/jci112450openalex-snapshot
Cyclosporin A reverses vincristine and daunorubicin resistance in acute lymphatic leukemia in vitro.
inferredcites →https://doi.org/10.1177/107327480301000207openalex-snapshot
Overcoming Multidrug Resistance in Cancer: An Update on the Clinical Strategy of Inhibiting P-Glycoprotein
inferredcites →https://doi.org/10.1200/jco.1996.14.2.610openalex-snapshot
Phase I study of etoposide with SDZ PSC 833 as a modulator of multidrug resistance in patients with cancer.
inferredcites →https://doi.org/10.2174/138945011795378540openalex-snapshot
Improving Cancer Chemotherapy with Modulators of ABC Drug Transporters
inferredcites →https://doi.org/10.2174/156800909788166583openalex-snapshot
A Review of Mechanisms of Circumvention and Modulation of Chemotherapeutic Drug Resistance
inferredcites →https://doi.org/10.2174/187152012803529655openalex-snapshot
Colon Adenocarcinoma Multidrug Resistance Reverted by Euphorbia Diterpenes: Structure-Activity Relationships and Pharmacophore Modeling
inferredcites →https://doi.org/10.5772/596openalex-snapshot
Advances in Grid Computing

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2021.112775zenodo-depositor-declared
Ingenane and jatrophane-type diterpenoids from Euphorbia kansui with multidrug resistance reversal activity
inferred← citeshttps://doi.org/10.1002/cbdv.201400260openalex-snapshot
Diterpene Constituents of Euphorbia exigua L. and Multidrug Resistance Reversing Activity of the Isolated Diterpenes
inferred← citeshttps://doi.org/10.1002/cbdv.201800386openalex-snapshot
Five New Diterpenoids from the Seeds of Euphorbia lathyris
inferred← citeshttps://doi.org/10.1002/cbdv.201900531openalex-snapshot
Synthesis of New Lathyrane Diterpenoid Derivatives from Euphorbia lathyris and Evaluation of Their Anti‐Inflammatory Activities
inferred← citeshttps://doi.org/10.1002/cbdv.202200411openalex-snapshot
Effects of Lipophilicity and Structural Features on the Antiherpes Activity of Digitalis Cardenolides and Derivatives
inferred← citeshttps://doi.org/10.1002/cbdv.202200918openalex-snapshot
Integration of LC/MS, NMR and Molecular Docking for Profiling of Bioactive Diterpenes from Euphorbia mauritanica L. with in Vitro Anti‐SARS‐CoV‐2 Activity
inferred← citeshttps://doi.org/10.1002/cbdv.202301061openalex-snapshot
Terpenoids from Euphorbia helioscopia and Their Cytotoxic Activities against H1975 Cells
inferred← citeshttps://doi.org/10.1002/cbic.201600316openalex-snapshot
A Cytochrome P450‐Mediated Intramolecular Carbon–Carbon Ring Closure in the Biosynthesis of Multidrug‐Resistance‐Reversing Lathyrane Diterpenoids
inferred← citeshttps://doi.org/10.1002/wcms.1196openalex-snapshot
Reversing cancer multidrug resistance: insights into the efflux by ABC transports from in silico studies
inferred← citeshttps://doi.org/10.1007/978-3-319-23476-2_10openalex-snapshot
Mechanistic and Pharmacological Insights into Modulation of ABC Drug Transporters by Tyrosine Kinase Inhibitors
inferred← citeshttps://doi.org/10.1007/s11101-014-9342-8openalex-snapshot
Euphorbia and Momordica metabolites for overcoming multidrug resistance
inferred← citeshttps://doi.org/10.1007/s11101-019-09615-1openalex-snapshot
Monoterpene indole alkaloids as leads for targeting multidrug resistant cancer cells from the African medicinal plant Tabernaemontana elegans
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.103546openalex-snapshot
Ingol diterpenoids as P-glycoprotein-dependent multidrug resistance (MDR) reversal agents from Euphorbia marginata
inferred← citeshttps://doi.org/10.1016/j.bioorg.2022.106329openalex-snapshot
Synthesis, antiproliferative and anti-MDR activities of lathyrane diterpene derivatives based on configuration inversion strategy
inferred← citeshttps://doi.org/10.1016/j.biopha.2019.109663openalex-snapshot
Lathyrane diterpenes from Euphorbia lathyris and the potential mechanism to reverse the multi-drug resistance in HepG2/ADR cells
inferred← citeshttps://doi.org/10.1016/j.bmc.2014.05.006openalex-snapshot
Macrocyclic diterpenes resensitizing multidrug resistant phenotypes
inferred← citeshttps://doi.org/10.1016/j.bmc.2014.09.041openalex-snapshot
Improving the MDR reversal activity of 6,17-epoxylathyrane diterpenes
inferred← citeshttps://doi.org/10.1016/j.bmc.2016.08.022openalex-snapshot
Triterpenoids from Momordica balsamina: Reversal of ABCB1-mediated multidrug resistance
inferred← citeshttps://doi.org/10.1016/j.bmc.2017.11.052openalex-snapshot
Monoterpene indole alkaloid azine derivatives as MDR reversal agents
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.01.044openalex-snapshot
Dregamine and tabernaemontanine derivatives as ABCB1 modulators on resistant cancer cells
inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.01.027openalex-snapshot
Jatrophane diterpenoids from Euphorbia sororia as potent modulators against P-glycoprotein-based multidrug resistance
inferred← citeshttps://doi.org/10.1016/j.fitote.2015.03.025openalex-snapshot
Reversal of P-glycoprotein-mediated multidrug resistance in MCF-7/Adr cancer cells by sesquiterpene coumarins
inferred← citeshttps://doi.org/10.1016/j.fitote.2018.02.014openalex-snapshot
Jatrophanes as promising multidrug resistance modulators: Advances of structure–activity relationships
inferred← citeshttps://doi.org/10.1016/j.fitote.2025.106405openalex-snapshot
Terpenoids and steroids from the whole plants of Euphorbia wallichii and their protective effects on STZ-induced damage in INS-1 cells
inferred← citeshttps://doi.org/10.1016/j.jep.2016.09.020openalex-snapshot
(3′R)-hydroxytabernaelegantine C: A bisindole alkaloid with potent apoptosis inducing activity in colon (HCT116, SW620) and liver (HepG2) cancer cells
inferred← citeshttps://doi.org/10.1016/j.phymed.2016.05.007openalex-snapshot
Jatrophane diterpenes and cancer multidrug resistance – ABCB1 efflux modulation and selective cell death induction
inferred← citeshttps://doi.org/10.1016/j.phymed.2024.155634openalex-snapshot
Anticancer diterpenes of African natural products: Mechanistic pathways and preclinical developments
inferred← citeshttps://doi.org/10.1016/j.phytochem.2014.04.020openalex-snapshot
Lathyrane-type diterpenoids from the seeds of Euphorbia lathyris
inferred← citeshttps://doi.org/10.1016/j.phytochem.2015.12.003openalex-snapshot
Diterpenoid constituents of Euphorbia macrorrhiza
inferred← citeshttps://doi.org/10.1016/j.phytochem.2018.12.003openalex-snapshot
Cytochrome P450 enzymes: A driving force of plant diterpene diversity
inferred← citeshttps://doi.org/10.1016/j.phytochem.2024.114256openalex-snapshot
Lathyrane and ent-isopimarane diterpenoids from Euphorbia wallichii and target prediction of active ingredient
inferred← citeshttps://doi.org/10.1016/j.phytol.2020.03.002openalex-snapshot
Cytotoxic diterpenoids from the roots of Euphorbia stracheyi
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5b00058openalex-snapshot
Lathyrol Diterpenes as Modulators of P-Glycoprotein Dependent Multidrug Resistance: Structure–Activity Relationship Studies on Euphorbia Factor L 3 Derivatives
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6b00525openalex-snapshot
Original Vinca Derivatives: From P-Glycoprotein Substrates to P-Glycoprotein Inhibitors
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6b00605openalex-snapshot
Jatrophane Diterpenoids as Modulators of P-Glycoprotein-Dependent Multidrug Resistance (MDR): Advances of Structure–Activity Relationships and Discovery of Promising MDR Reversal Agents
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5b00370openalex-snapshot
Epoxylathyrol Derivatives: Modulation of ABCB1-Mediated Multidrug Resistance in Human Colon Adenocarcinoma and Mouse T-Lymphoma Cells
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5b00631openalex-snapshot
12,17-Cyclojatrophane and Jatrophane Constituents of Euphorbia welwitschii
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6b00627openalex-snapshot
Drug Affinity Responsive Target Stability (DARTS) Identifies Laurifolioside as a New Clathrin Heavy Chain Modulator
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6b00644openalex-snapshot
Euphorbia dendroides Latex as a Source of Jatrophane Esters: Isolation, Structural Analysis, Conformational Study, and Anti-CHIKV Activity
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6b01084openalex-snapshot
Exploring Jolkinol D Derivatives To Overcome Multidrug Resistance in Cancer
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.9b00519openalex-snapshot
Macrocyclic Diterpenoids from Euphorbia helioscopia and Their Potential Anti-inflammatory Activity
inferred← citeshttps://doi.org/10.1021/acs.orglett.2c03172openalex-snapshot
Ir-Catalyzed Biomimetic Photoisomerization of Cyclopropane in Lathyrane-Type Euphorbia Diterpenes
inferred← citeshttps://doi.org/10.1021/acs.orglett.6c02633openalex-snapshot
Rearranged Jatrophane Diterpenoids from Euphorbia helioscopia with 5/6/6/4 and 5/6/6/5 Fused Skeletons and Potent Anti-ZIKV Activity
inferred← citeshttps://doi.org/10.1021/acs.orglett.9b04029openalex-snapshot
Jatrofolianes A and B: Two Highly Modified Lathyrane Diterpenoids from Jatropha gossypiifolia
inferred← citeshttps://doi.org/10.1021/ci400195vopenalex-snapshot
Molecular Docking Characterizes Substrate-Binding Sites and Efflux Modulation Mechanisms within P-Glycoprotein.
inferred← citeshttps://doi.org/10.1039/c4ob02282copenalex-snapshot
Systematic methodology for the development of biocatalytic hydrogen-borrowing cascades: application to the synthesis of chiral α-substituted carboxylic acids from α-substituted α,β-unsaturated aldehydes
inferred← citeshttps://doi.org/10.1039/c5np00121hopenalex-snapshot
The use of isolated natural products as scaffolds for the generation of chemically diverse screening libraries for drug discovery
inferred← citeshttps://doi.org/10.1039/d2np00047dopenalex-snapshot
Euphorbia diterpenoids: isolation, structure, bioactivity, biosynthesis, and synthesis (2013–2021)
inferred← citeshttps://doi.org/10.1073/pnas.2203890119openalex-snapshot
Gene discovery and virus-induced gene silencing reveal branched pathways to major classes of bioactive diterpenoids in Euphorbia peplus
inferred← citeshttps://doi.org/10.1080/14786419.2022.2095379openalex-snapshot
Microbial and chemical transformations of euphorbia factor L1 and the P-glycoprotein inhibitory activity in zebrafishes
inferred← citeshttps://doi.org/10.1111/cbdd.13473openalex-snapshot
Pharmacophoric features for a very potent 5‐spirofluorenehydantoin inhibitor of cancer efflux pump ABCB 1, based on X‐ray analysis
inferred← citeshttps://doi.org/10.1177/1934578x221105691openalex-snapshot
The Role of Ingenane Diterpenes in Cancer Therapy: From Bioactive Secondary Compounds to Small Molecules
inferred← citeshttps://doi.org/10.1186/s13321-022-00635-2openalex-snapshot
Using Jupyter Notebooks for re-training machine learning models
inferred← citeshttps://doi.org/10.23860/diss-bin-muhsinah-abdullatif-2018openalex-snapshot
Phytochemical Investigation of a Native North American Species, “Acer saccarinum” and an Endemic Saudi Arabian Species, “Euphorbia saudiarabica”
inferred← citeshttps://doi.org/10.3389/fphar.2020.00599openalex-snapshot
Epoxylathyrane Derivatives as MDR-Selective Compounds for Disabling Multidrug Resistance in Cancer
inferred← citeshttps://doi.org/10.3389/fphar.2022.815603openalex-snapshot
Research Progress on Natural Diterpenoids in Reversing Multidrug Resistance
inferred← citeshttps://doi.org/10.3390/molecules22060871openalex-snapshot
Natural Products as Alternative Choices for P-Glycoprotein (P-gp) Inhibition
inferred← citeshttps://doi.org/10.3390/ph15070780openalex-snapshot
Pharmacological Potential of Lathyrane-Type Diterpenoids from Phytochemical Sources
inferred← citeshttps://doi.org/10.3390/pharmaceutics10030127openalex-snapshot
The Effects of Synthetically Modified Natural Compounds on ABC Transporters
inferred← citeshttps://doi.org/10.3390/plants12244181openalex-snapshot
LC-ESI QToF MS Non-Targeted Screening of Latex Extracts of Euphorbia seguieriana ssp. seguieriana Necker and Euphorbia cyparissias and Determination of Their Potential Anticancer Activity
inferred← citeshttps://doi.org/10.3390/plants15142235openalex-snapshot
Lathyrane Diterpenoids: Half-Century of Chemical Insights and Therapeutic Potential
inferred← citeshttps://doi.org/10.4155/fmc-2017-0228openalex-snapshot
Optimizing the Flavanone Core Toward New Selective Nitrogen-Containing Modulators of ABC Transporters
inferred← citeshttps://doi.org/10.4155/fmc.16.11openalex-snapshot
Optimizing the Macrocyclic Diterpenic Core Toward the Reversal of Multidrug Resistance in Cancer
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.