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The use of isolated natural products as scaffolds for the generation of chemically diverse screening libraries for drug discovery
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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From protein domains to drug candidates – natural products as guiding principles in
inferredcites →https://doi.org/10.1002/1521-3773(20020816)41:16<2878::aid-anie2878>3.0.co;2-bopenalex-snapshot
From Protein Domains to Drug Candidates—Natural Products as Guiding Principles in the Design and Synthesis of Compound Libraries
inferredcites →https://doi.org/10.1002/cmdc.201200516openalex-snapshot
Optimization of Marine Triterpene Sipholenols as Inhibitors of Breast Cancer Migration and Invasion
inferredcites →https://doi.org/10.1007/s40362-013-0014-7openalex-snapshot
Scaffold Flatness: Reversing the Trend
inferredcites →https://doi.org/10.1016/0041-0101(74)90192-5openalex-snapshot
Sarcophine—a new toxin from the soft coral Sarcophyton glaucum (Alcyonaria)
inferredcites →https://doi.org/10.1016/j.bmc.2011.06.060openalex-snapshot
Semisynthetic analogues of the marine cembranoid sarcophine as prostate and breast cancer migration inhibitors
inferredcites →https://doi.org/10.1016/j.bmc.2012.09.052openalex-snapshot
Synthesis and antimalarial evaluation of a screening library based on a tetrahydroanthraquinone natural product scaffold
inferredcites →https://doi.org/10.1016/j.bmcl.2006.03.029openalex-snapshot
Design and semisynthesis of novel fredericamycin A derivatives with an improved antitumor profile
inferredcites →https://doi.org/10.1016/j.bmcl.2007.02.007openalex-snapshot
Synthesis and evaluation of diverse thio avarol derivatives as potential UVB photoprotective candidates
inferredcites →https://doi.org/10.1016/j.bmcl.2007.12.062openalex-snapshot
Novel echinocandin antifungals. Part 1: Novel side-chain analogs of the natural product FR901379
inferredcites →https://doi.org/10.1016/j.bmcl.2008.03.093openalex-snapshot
Novel echinocandin antifungals. Part 2: Optimization of the side chain of the natural product FR901379. Discovery of micafungin
inferredcites →https://doi.org/10.1016/j.cbpa.2004.04.011openalex-snapshot
Natural products and combinatorial chemistry: back to the future
inferredcites →https://doi.org/10.1016/j.drudis.2013.10.013openalex-snapshot
Natural products as lead structures: chemical transformations to create lead-like libraries
inferredcites →https://doi.org/10.1016/j.ejmech.2013.04.066openalex-snapshot
Synthesis of novel guttiferone A derivatives: In-vitro evaluation toward Plasmodium falciparum, Trypanosoma brucei and Leishmania donovani
inferredcites →https://doi.org/10.1016/j.ejmech.2013.11.039openalex-snapshot
Optimization, pharmacophore modeling and 3D-QSAR studies of sipholanes as breast cancer migration and proliferation inhibitors
inferredcites →https://doi.org/10.1016/j.ejmech.2014.04.028openalex-snapshot
Semisynthesis and in vitro cytotoxic evaluation of new analogues of 1-O-acetylbritannilactone, a sesquiterpene from Inula britannica
inferredcites →https://doi.org/10.1016/j.lfs.2006.08.003openalex-snapshot
Identification of avarol derivatives as potential antipsoriatic drugs using an in vitro model for keratinocyte growth and differentiation
inferredcites →https://doi.org/10.1016/j.tetlet.2003.12.123openalex-snapshot
Rapid access to epothilone analogs via semisynthetic degradation and reconstruction of epothilone D
inferredcites →https://doi.org/10.1016/s0031-9422(00)90813-6openalex-snapshot
Sesquiterpene lactones from Inula britannica
inferredcites →https://doi.org/10.1016/s0040-4020(01)85139-5openalex-snapshot
A new stereochemical class of bicyclic sesquiterpenes from eremophila virgata W.V. Fitzg. (Myoporaceae)
inferredcites →https://doi.org/10.1016/s0040-4020(01)89039-6openalex-snapshot
The guttiferones, HIV-inhibitory benzophenones from Symphonia globulifera, Garcinia livingstonei, Garcinia ovalifolia and Clusia rosea
inferredcites →https://doi.org/10.1016/s0040-4020(01)97451-4openalex-snapshot
Sarcophine, a new epoxy cembranolide from marine origin
inferredcites →https://doi.org/10.1016/s0040-4039(00)93940-6openalex-snapshot
The structure of new lathyrane diterpenes, jolkinols a, b, c, and d, from Euphorbia jolkini boiss.
inferredcites →https://doi.org/10.1016/s0040-4039(01)91918-5openalex-snapshot
Avarol a novel sesquiterpenoid hydroquinone with a rearranged drimane skeleton from the sponge
inferredcites →https://doi.org/10.1016/s0960-894x(02)00469-9openalex-snapshot
Muraymycins, novel peptidoglycan biosynthesis inhibitors: semisynthesis and SAR of Their derivatives
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Analysis of Physicochemical Properties for Drugs of Natural Origin
inferredcites →https://doi.org/10.1021/cc0500351openalex-snapshot
Natural Products as Scaffolds for Chemical Diversification: Solution-Phase Parallel Synthesis of a Series of Naringin Analogues
inferredcites →https://doi.org/10.1021/co500051zopenalex-snapshot
Solid-Phase Library Synthesis of Bi-Functional Derivatives of Oleanolic and Maslinic Acids and Their Cytotoxicity on Three Cancer Cell Lines
inferredcites →https://doi.org/10.1021/cr400442vopenalex-snapshot
Development of a Natural-Product-Derived Chemical Toolbox for Modulation of Protein Function
inferredcites →https://doi.org/10.1021/ja00280a055openalex-snapshot
Manzamine A, a novel antitumor alkaloid from a sponge
inferredcites →https://doi.org/10.1021/ja017748hopenalex-snapshot
Structures of the Muraymycins, Novel Peptidoglycan Biosynthesis Inhibitors
inferredcites →https://doi.org/10.1021/jm020155copenalex-snapshot
Do Structurally Similar Molecules Have Similar Biological Activity?
inferredcites →https://doi.org/10.1021/jm301441wopenalex-snapshot
Enhancing Macrocyclic Diterpenes as Multidrug-Resistance Reversers: Structure–Activity Studies on Jolkinol D Derivatives
inferredcites →https://doi.org/10.1021/jm900672topenalex-snapshot
Structure−Activity Relationship and Mechanism of Action Studies of Manzamine Analogues for the Control of Neuroinflammation and Cerebral Infections
inferredcites →https://doi.org/10.1021/jo00168a029openalex-snapshot
The sipholanes, a novel group of triterpenes from the marine sponge Siphonochalina siphonella
inferredcites →https://doi.org/10.1021/jo9813134openalex-snapshot
Structurally Novel Bioconversion Products of the Marine Natural Product Sarcophine Effectively Inhibit JB6 Cell Transformation
inferredcites →https://doi.org/10.1021/np049873nopenalex-snapshot
Potential Antipsoriatic Avarol Derivatives as Antioxidants and Inhibitors of PGE2Generation and Proliferation in the HaCaT Cell Line
inferredcites →https://doi.org/10.1021/np060092ropenalex-snapshot
Glycogen Synthase Kinase-3 (GSK-3) Inhibitory Activity and Structure–Activity Relationship (SAR) Studies of the Manzamine Alkaloids. Potential for Alzheimer’s Disease
inferredcites →https://doi.org/10.1021/np200906sopenalex-snapshot
Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
inferredcites →https://doi.org/10.1021/np500856uopenalex-snapshot
Design and Synthesis of a Screening Library Using the Natural Product Scaffold 3-Chloro-4-hydroxyphenylacetic Acid
inferredcites →https://doi.org/10.1021/np800318mopenalex-snapshot
Synthesis and Biological Activities of Thio-avarol Derivatives
inferredcites →https://doi.org/10.1021/np9004932openalex-snapshot
An Approach to the Site-Selective Diversification of Apoptolidin A with Peptide-Based Catalysts
inferredcites →https://doi.org/10.1021/ol027366wopenalex-snapshot
Toward a Structure−Activity Relationship for Apoptolidin: Selective Functionalization of the Hydroxyl Group Array
inferredcites →https://doi.org/10.1038/513481aopenalex-snapshot
Chemistry: Chemical con artists foil drug discovery
inferredcites →https://doi.org/10.1039/b206953aopenalex-snapshot
Natural product-derived building blocks for combinatorial synthesis. Part 1. Fragmentation of natural products from myxobacteria
inferredcites →https://doi.org/10.1039/b715668popenalex-snapshot
Scaffold diversity of natural products: inspiration for combinatorial library design
inferredcites →https://doi.org/10.1039/c2ob00029fopenalex-snapshot
Design and synthesis of screening libraries based on the muurolane natural product scaffold
inferredcites →https://doi.org/10.1039/c3np70063aopenalex-snapshot
Natural products as starting points for the synthesis of complex and diverse compounds
inferredcites →https://doi.org/10.1039/c3np70087aopenalex-snapshot
Chemo- and site-selective derivatizations of natural products enabling biological studies
inferredcites →https://doi.org/10.1039/c5ob00169bopenalex-snapshot
Design and synthesis of analogues of natural products
inferredcites →https://doi.org/10.1071/ch01123openalex-snapshot
The Synthesis of a Combinatorial Library Using a Tambjamine Natural Product Template
inferredcites →https://doi.org/10.1071/ch9672199openalex-snapshot
(+)-(5S)-δ-Lactone of 5-hydroxy-7-phenylhepta-2,6-dienoic acid, a natural product from Cryptocarya caloneura (Scheff.) Kostermans
inferredcites →https://doi.org/10.1248/cpb.53.1387openalex-snapshot
Semisynthesis and Antitumor Activities of New Styryl-Lactone Derivatives
inferredcites →https://doi.org/10.4155/fmc.12.55openalex-snapshot
Guiding Principles for Natural Product Drug Discovery
inferredcites →https://doi.org/10.7164/antibiotics.33.166openalex-snapshot
Bu-2313, a new antibiotic complex active against anaerobes. II. Structure determination of Bu-2313 A and B.
inferredcites →https://doi.org/10.7164/antibiotics.33.173openalex-snapshot
Bu-2313, a new antibiotic complex active against anaerobes. III. Semi-synthesis of Bu-2313 A and B, and their analogs.
inferredcites →https://doi.org/10.7164/antibiotics.34.1389openalex-snapshot
Fredericamycin A a new antitumor antibiotic. I. Production, isolation and physicochemical properties.
inferredcites →https://doi.org/10.7164/antibiotics.47.1084openalex-snapshot
WF11899A, B and C, novel antifungal lipopeptides. I. Taxonomy, fermentation, isolation and physico-chemical properties.
inferredcites →https://doi.org/10.7164/antibiotics.47.1092openalex-snapshot
WF11899A, B and C, novel antifungal lipopeptides. II. Biological properties.
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Diversity-oriented semi-synthesis of Alantolactone and Isoalantolactone hybrids employing azomethine ylide cycloaddition pathway
inferred← citeshttps://doi.org/10.1016/j.phrs.2024.107099openalex-snapshot
Natural products for combating multidrug resistance in cancer
inferred← citeshttps://doi.org/10.1016/j.phymed.2025.157380openalex-snapshot
Tissue engineering with bionanomaterials: A new frontier
inferred← citeshttps://doi.org/10.1016/j.sajb.2022.05.028openalex-snapshot
Natural bioactive products as promising therapeutics: A review of natural product-based drug development
inferred← citeshttps://doi.org/10.1016/j.tet.2020.131801openalex-snapshot
Chemical derivatization of natural products: Semisynthesis and pharmacological aspects- A decade update
inferred← citeshttps://doi.org/10.1016/j.tet.2024.134366openalex-snapshot
Anthelmintic activity of selected neolignans and semisynthetic derivatives from Styrax suberifolius
inferred← citeshttps://doi.org/10.1016/j.tet.2025.134634openalex-snapshot
Oximes and hydrazones as versatile directing groups: A critical review on C–H activation and functionalization
inferred← citeshttps://doi.org/10.1016/j.tet.2025.135104openalex-snapshot
Synthesis and antibacterial evaluation of a unique amide library based on the marine natural product 3,5-dibromo-4-methoxybenzoic acid
inferred← citeshttps://doi.org/10.1016/j.toxlet.2016.04.013openalex-snapshot
Molecular mechanisms of endocrine and metabolic disruption: An in silico study on antitrypanosomal natural products and some derivatives
inferred← citeshttps://doi.org/10.1016/j.vetpar.2017.07.005openalex-snapshot
Screening of a small, well-curated natural product-based library identifies two rotenoids with potent nematocidal activity against Haemonchus contortus
inferred← citeshttps://doi.org/10.1016/s1875-5364(24)60603-5openalex-snapshot
Traditional Chinese medicines derived natural inhibitors of ferroptosis on ischemic stroke
inferred← citeshttps://doi.org/10.1016/s1875-5364(25)60942-3openalex-snapshot
Identification of natural product-based drug combination (NPDC) using artificial intelligence
inferred← citeshttps://doi.org/10.1021/acs.analchem.9b02697openalex-snapshot
Molecular Crowding Evolution for Enabling Discovery of Enthalpy-Driven Aptamers for Robust Biomedical Applications
inferred← citeshttps://doi.org/10.1021/acs.jafc.3c02497openalex-snapshot
Discovery of Natural Sesquiterpene Lactone 1-O-Acetylbritannilactone Analogues Bearing Oxadiazole, Triazole, or Imidazole Scaffolds for the Development of New Fungicidal Candidates
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6b00473openalex-snapshot
Underexplored Opportunities for Natural Products in Drug Discovery
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.0c00121openalex-snapshot
Synthesis of a Unique Psammaplysin F Library and Functional Evaluation in Prostate Cancer Cells by Multiparametric Quantitative Single Cell Imaging
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.2c00229openalex-snapshot
Identification of Anthelmintic Bishomoscalarane Sesterterpenes from the Australian Marine Sponge Phyllospongia bergquistae and Structure Revision of Phyllolactones A–D
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.2c00880openalex-snapshot
Synthesis, Optical Properties, and Antiproliferative Evaluation of NBD-Triterpene Fluorescent Probes
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.2c01041openalex-snapshot
Using a Bioactive Eremophila -Derived Serrulatane Scaffold to Generate a Unique Carbamate Library for Anti-infective Evaluations
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.4c00190openalex-snapshot
A Fast and Efficient Molecular Networking Approach for Reactivity of Natural Products Exploration in Plant Extracts: Application to Diterpene Esters from Euphorbia dendroides
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.4c00364openalex-snapshot
Rapid Access to Tigliane, Ingenane, and Rhamnofolane Diterpenes from a Lathyrane Precursor via Biomimetic Skeleton Transformation Strategy
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.7b00236openalex-snapshot
Oxidation of the Meroterpenoid (−)-Terreumol C from the Mushroom Tricholoma terreum: Discovery of Cytotoxic Analogues
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.7b00929openalex-snapshot
Identification of Gibberellic Acid Derivatives That Deregulate Cholesterol Metabolism in Prostate Cancer Cells
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.8b00326openalex-snapshot
Terpenoids fromEuphorbia pedroias Multidrug-Resistance Reversers
inferred← citeshttps://doi.org/10.1021/acs.joc.3c00169openalex-snapshot
Synthesis of Aza-Bridged Perhydroazulene Chimeras of Tropanes and Hederacine A
inferred← citeshttps://doi.org/10.1021/acs.joc.5c00392openalex-snapshot
Rh(III)-Catalyzed Fabrication of [4,3,1]-Bridged Azaheterocycles using Quinone Monoacetals
inferred← citeshttps://doi.org/10.1021/acs.joc.8b02112openalex-snapshot
Metal-Free [2 + 2 + 2] Cycloaddition of Ynamide–Nitriles with Ynamides: A Highly Regio- and Chemoselective Synthesis of δ-Carboline Derivatives
inferred← citeshttps://doi.org/10.1021/acs.orglett.0c01593openalex-snapshot
Isolation, Total Synthesis, and Absolute Configuration Determination of Renoprotective Dimeric N-Acetyldopamine–Adenine Hybrids from the Insect Aspongopus chinensis
inferred← citeshttps://doi.org/10.1021/acs.orglett.5c01770openalex-snapshot
Biomimetic Skeleton Conversion from Lathyrane into Euphoractine A-Type Euphorbia Diterpenes: Semisynthesis of Natural Diterpenes Euphoractins M and N
inferred← citeshttps://doi.org/10.1021/acs.orglett.6c00352openalex-snapshot
Bioinspired Synthesis of Curtachalasin A and Δ 6,12 -Curtachalasin N Enabled by Tandem Transannular Epoxyalkene Cyclization and α-Ketol Rearrangement
inferred← citeshttps://doi.org/10.1021/acsami.4c09689openalex-snapshot
Carbon-Dots-Mediated Improvement of Antimicrobial Activity of Natural Products
inferred← citeshttps://doi.org/10.1021/acscatal.2c04208openalex-snapshot
Uniquely Enabling Mechanism for Bis-oxazoline Copper(II)-Catalyzed Azidation of Pyranosides and Furanosides
inferred← citeshttps://doi.org/10.1021/acschembio.7b00851openalex-snapshot
Advances in the Chemical Biology of Desferrioxamine B
inferred← citeshttps://doi.org/10.1021/acschemneuro.1c00712openalex-snapshot
Fustin Inhibits Oxidative Free Radicals and Inflammatory Cytokines in Cerebral Cortex and Hippocampus and Protects Cognitive Impairment in Streptozotocin-Induced Diabetic Rats
inferred← citeshttps://doi.org/10.1021/acsmedchemlett.2c00163openalex-snapshot
(−)-Epigallocatechin Gallate is a Noncompetitive Inhibitor of NAD Kinase
inferred← citeshttps://doi.org/10.1021/acsomega.0c06202openalex-snapshot
Total Synthesis of 6‑Hydroxymetatacarboline‑ d Discovered from Mycena metata via the Pictet–Spengler Reaction Followed by the Horner–Wadsworth–Emmons Reaction
inferred← citeshttps://doi.org/10.1021/acsomega.2c01341openalex-snapshot
Protective Effect of Fustin Against Ethanol-Activated Gastric Ulcer via Downregulation of Biochemical Parameters in Rats
inferred← citeshttps://doi.org/10.1021/acsomega.5c13679openalex-snapshot
Design, Synthesis, and Biological Evaluation of Methoxy-Substituted Chalcones and Gypsogenin-Based Hybrids as Anticancer and Antimicrobial Agents
inferred← citeshttps://doi.org/10.1021/jacs.0c09504openalex-snapshot
A Diverse Library of Chiral Cyclopropane Scaffolds via Chemoenzymatic Assembly and Diversification of Cyclopropyl Ketones
inferred← citeshttps://doi.org/10.1021/jacsau.4c00912openalex-snapshot
Antarmycins: Discovery, Biosynthesis, Anti-pathogenic Bacterial Activity, and Mechanism of Action from Deep-Sea-Derived Pseudonocardia antarctica
inferred← citeshttps://doi.org/10.1038/nchem.2863openalex-snapshot
Late-stage chemoselective functional-group manipulation of bioactive natural products with super-electrophilic silylium ions
inferred← citeshttps://doi.org/10.1038/s41401-021-00653-0openalex-snapshot
Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase
inferred← citeshttps://doi.org/10.1038/s41429-020-0359-5openalex-snapshot
Semi-synthesis of antibacterial dialkylresorcinol derivatives
inferred← citeshttps://doi.org/10.1038/s41573-020-00114-zopenalex-snapshot
Natural products in drug discovery: advances and opportunities
inferred← citeshttps://doi.org/10.1038/s41598-018-20192-9openalex-snapshot
Diversity Modification and Structure-Activity Relationships of Two Natural Products 1β-hydroxy Alantolactone and Ivangustin as Potent Cytotoxic Agents
inferred← citeshttps://doi.org/10.1038/s41598-020-57793-2openalex-snapshot
The plant natural product 2-methoxy-1,4-naphthoquinone stimulates therapeutic neural repair properties of olfactory ensheathing cells
inferred← citeshttps://doi.org/10.1038/s42004-025-01779-6openalex-snapshot
Metabolic engineering and late-stage functionalization expand the chemical space of the antimalarial premarineosin A
inferred← citeshttps://doi.org/10.1039/c6ob01216gopenalex-snapshot
Natural product inspired design and synthesis of β-carboline and γ-lactone based molecular hybrids
inferred← citeshttps://doi.org/10.1039/c6ra04841bopenalex-snapshot
In(OTf) 3 catalysed an expeditious synthesis of β-carboline–imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrazine conjugates
inferred← citeshttps://doi.org/10.1039/c6ra05373dopenalex-snapshot
Chemical diversification of essential oils, evaluation of complex mixtures and identification of a xanthine oxidase inhibitor
inferred← citeshttps://doi.org/10.1039/c6ra15875gopenalex-snapshot
Metal-free 1,3-dipolar cycloaddition approach towards the regioselective synthesis of β-carboline and isoxazole based molecular hybrids
inferred← citeshttps://doi.org/10.1039/c7md00090aopenalex-snapshot
Dichloro-naphthoquinone as a non-classical inhibitor of the mycobacterial carbonic anhydrase Rv3588c
inferred← citeshttps://doi.org/10.1039/c8ob01388hopenalex-snapshot
Natural products as modulators of the cyclic-AMP pathway: evaluation and synthesis of lead compounds
inferred← citeshttps://doi.org/10.1039/c8ob01456fopenalex-snapshot
(−)-Cytisine: Access to a stereochemically defined and functionally flexible piperidine scaffold
inferred← citeshttps://doi.org/10.1039/c8ra01840eopenalex-snapshot
Anti-inflammatory butenolide derivatives from the coral-derived fungus Aspergillus terreus and structure revisions of aspernolides D and G, butyrolactone VI and 4′,8′′-diacetoxy butyrolactone VI
inferred← citeshttps://doi.org/10.1039/c8ra06238bopenalex-snapshot
Synthesis and anticancer studies of Michael adducts and Heck arylation products of sesquiterpene lactones, zaluzanin D and zaluzanin C from Vernonia arborea
inferred← citeshttps://doi.org/10.1039/d1ob00448dopenalex-snapshot
Contemporary advancements in the semi-synthesis of bioactive terpenoids and steroids
inferred← citeshttps://doi.org/10.1039/d1sc04471kopenalex-snapshot
Natural product drug discovery in the artificial intelligence era
inferred← citeshttps://doi.org/10.1039/d2qo00055eopenalex-snapshot
Biocatalytic and chemical derivatization of the fungal meroditerpenoid chevalone E
inferred← citeshttps://doi.org/10.1039/d3cc01644gopenalex-snapshot
C–H modification of natural products: a minimalist enabling tactic for drug discovery, API processing and bioconjugation
inferred← citeshttps://doi.org/10.1039/d3ra06831eopenalex-snapshot
Challenges in natural product-based drug discovery assisted with in silico -based methods
inferred← citeshttps://doi.org/10.1039/d4qo01111bopenalex-snapshot
Recent advances in late-stage monofluorination of natural products and their derivatives
inferred← citeshttps://doi.org/10.1039/d5qo00984gopenalex-snapshot
Expanding the silyl-Prins toolbox: selective access to C4-quaternary stereocenters in tetrahydropyrans using internal cyclopropylsilyl alcohols
inferred← citeshttps://doi.org/10.1039/d6ob00865hopenalex-snapshot
Artificial intelligence-guided discovery of marine scalaranes as selective COX-2 inhibitors through machine learning and molecular modelling
inferred← citeshttps://doi.org/10.1039/d6qo00727aopenalex-snapshot
From nature to synthetic analogues: recent advances in the design and synthesis of natural product-based libraries
inferred← citeshttps://doi.org/10.1039/d6ra06055bopenalex-snapshot
Natural product-modified BODIPY: design strategies, photophysical properties and biomedical applications
inferred← citeshttps://doi.org/10.1055/a-1031-7328openalex-snapshot
Protective Role of Casuarinin from Melaleuca leucadendra against Ethanol-Induced Gastric Ulcer in Rats
inferred← citeshttps://doi.org/10.1070/rcr4810openalex-snapshot
Synthesis of oxygen-containing heterocyclic compounds based on monoterpenoids
inferred← citeshttps://doi.org/10.1073/pnas.1914777117openalex-snapshot
Pyridoxal-5′-phosphate–dependent bifunctional enzyme catalyzed biosynthesis of indolizidine alkaloids in fungi
inferred← citeshttps://doi.org/10.1080/00914037.2018.1539989openalex-snapshot
Biological evaluation of bioavailable amphiphilic polymeric conjugate based-on natural products: diosgenin and curcumin
inferred← citeshttps://doi.org/10.1080/07391102.2023.2203249openalex-snapshot
Identification of terpenoids as dihydropteroate synthase and dihydrofolate reductase inhibitors through structure-based virtual screening and molecular dynamic simulations
inferred← citeshttps://doi.org/10.1080/0972060x.2023.2270697openalex-snapshot
Chemical profile and radical scavenging of the Psidium guajava flower’s essential oil: Molecular docking study on the human cytochrome P450 CYP2C9
inferred← citeshttps://doi.org/10.1080/10286020.2026.2740154openalex-snapshot
Discovery and semisynthesis of coniochaetones N–P: antimicrobial and antioxidant heterocyclics from an Antarctic-derived fungus Penicillium sp. S2014503
inferred← citeshttps://doi.org/10.1080/14786419.2019.1662005openalex-snapshot
Paeoniflorin benzoates: synthesis and influence on learning and memory of aged rats in the passive avoidance task
inferred← citeshttps://doi.org/10.1080/14786419.2019.1663513openalex-snapshot
Synthesis of new selective cytotoxic ricinine analogues against oral squamous cell carcinoma
inferred← citeshttps://doi.org/10.1080/14786419.2026.2683115openalex-snapshot
Semi-synthesis of novel dispiro hybrids of sesquiterpene lactones by using benzylamines via azomethine ylide cycloaddition
inferred← citeshttps://doi.org/10.1096/fj.201700288ropenalex-snapshot
Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain
inferred← citeshttps://doi.org/10.1155/joch/9292736openalex-snapshot
Extraction and Characterization of Tetralin‐Pentacyclic Triterpenoid Conjugates From Water Hyacinth ( Pontederia crassipes ) (Mart.) Solms: A Computational Approach to Evaluate Their Pharmacokinetics and Anti‐HIV Potential
inferred← citeshttps://doi.org/10.11606/t.59.2023.tde-30012024-145043openalex-snapshot
Efeito das proteínas NSP4 e ORF9b de SARS-CoV-2 sobre a viabilidade celular e identificação de ligantes contra NSP4
inferred← citeshttps://doi.org/10.1177/17475198211047801openalex-snapshot
Antitubercular and antibacterial activities of isoxazolines derived from natural products: Isoxazolines as inhibitors of Mycobacterium tuberculosis InhA
inferred← citeshttps://doi.org/10.1248/cpb.c23-00039openalex-snapshot
Computer Science Technology in Natural Products Research: A Review of Its Applications and Implications
inferred← citeshttps://doi.org/10.15446/rcciquifa.v49n1.87026openalex-snapshot
Descubrimiento de fármacos basado en imagenología de células vivas
inferred← citeshttps://doi.org/10.18632/oncotarget.13367openalex-snapshot
Induction of the mitochondria-mediated apoptosis in human esophageal cancer cells by DS2, a newly synthetic diterpenoid analog, is regulated by Bax and caused by generation of reactive oxygen species
inferred← citeshttps://doi.org/10.21577/0103-5053.20230193openalex-snapshot
Semisynthesis and Cytotoxic Activities of Novel Oxime Ester Derivatives of the Diterpene Stemodin
inferred← citeshttps://doi.org/10.21577/1984-6835.20200138openalex-snapshot
Pathophysiological Aspects of Inflammation and Drug Design: an Updated Overview
inferred← citeshttps://doi.org/10.2174/0118756298357295250214114611openalex-snapshot
Advances in the Application of Mass Spectrometry in the Study of Alkaloid Structure
inferred← citeshttps://doi.org/10.2174/1389201022666210122125131openalex-snapshot
Anti-anxiety Properties of Selected Medicinal Plants
inferred← citeshttps://doi.org/10.2174/1389557522666220511140527openalex-snapshot
Potential of Phytomolecules in Alliance with Nanotechnology to Surmount the Limitations of Current Treatment Options in the Management of Osteoarthritis
inferred← citeshttps://doi.org/10.2174/1570159x21666230717144752openalex-snapshot
Neuroprotective Strategies for Stroke by Natural Products: Advances and Perspectives
inferred← citeshttps://doi.org/10.2174/1573407216666200210122751openalex-snapshot
Glycyrrhizic Acid Derivatives as New Antiviral and Immune Modulating Agents
inferred← citeshttps://doi.org/10.21863/jstr/2025.15.2.011openalex-snapshot
Natural Compounds as Potential Inhibitors of PIK3CG for the Management of Triple-Negative Breast Cancer: A Biocomputational Study
inferred← citeshttps://doi.org/10.22270/jddt.v13i9.6221openalex-snapshot
Antibacterial and antifungal activity of Combretum farinosum Kunth and Combretum igneiflorum Rendón & R. Delgad. extracts
inferred← citeshttps://doi.org/10.30574/wjarr.2022.16.2.1128openalex-snapshot
Medicinal plant derived drugs and their treatment for human diseases like cancer: A review
inferred← citeshttps://doi.org/10.3389/fbinf.2025.1689172openalex-snapshot
In silico identification of novel natural compounds as potential KIFC1 inhibitors for the therapeutic intervention of triple-negative breast cancer
inferred← citeshttps://doi.org/10.3389/fmicb.2018.03151openalex-snapshot
Red Fluorescent Chlamydia trachomatis Applied to Live Cell Imaging and Screening for Antibacterial Agents
inferred← citeshttps://doi.org/10.3390/biology11050624openalex-snapshot
Filamentous Thermosensitive Mutant Z: An Appealing Target for Emerging Pathogens and a Trek on Its Natural Inhibitors
inferred← citeshttps://doi.org/10.3390/biom11121805openalex-snapshot
Towards the De Novo Design of HIV-1 Protease Inhibitors Based on Natural Products
inferred← citeshttps://doi.org/10.3390/biom15081071openalex-snapshot
Optimization and Characterization of Bioactive Metabolites from Cave-Derived Rhodococcus jialingiae C1
inferred← citeshttps://doi.org/10.3390/ijms22073676openalex-snapshot
Anticancer Potential of Betulonic Acid Derivatives
inferred← citeshttps://doi.org/10.3390/ijms241210204openalex-snapshot
Bromotyrosine-Derived Metabolites from a Marine Sponge Inhibit Pseudomonas aeruginosa Biofilms
inferred← citeshttps://doi.org/10.3390/ijms242015142openalex-snapshot
Biological Evaluation of 8-Methoxy-2,5-dimethyl-5H-indolo[2,3-b] Quinoline as a Potential Antitumor Agent via PI3K/AKT/mTOR Signaling
inferred← citeshttps://doi.org/10.3390/md15010002openalex-snapshot
Pyran Rings Containing Polyketides from Penicillium raistrickii
inferred← citeshttps://doi.org/10.3390/microorganisms11061585openalex-snapshot
Co-Expression of Transcriptional Regulators and Housekeeping Genes in Streptomyces spp.: A Strategy to Optimize Metabolite Production
inferred← citeshttps://doi.org/10.3390/molecules22101715openalex-snapshot
Screening a Natural Product-Based Library against Kinetoplastid Parasites
inferred← citeshttps://doi.org/10.3390/molecules23061444openalex-snapshot
Pentacyclic Triterpenes from Cecropia telenitida Can Function as Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1
inferred← citeshttps://doi.org/10.3390/molecules25020260openalex-snapshot
Meroterpene-Like α-Glucosidase Inhibitors Based on Biomimetic Reactions Starting from β-Caryophyllene
inferred← citeshttps://doi.org/10.3390/molecules28020474openalex-snapshot
Structure-Based Identification of Natural-Product-Derived Compounds with Potential to Inhibit HIV-1 Entry
inferred← citeshttps://doi.org/10.3390/molecules28104186openalex-snapshot
Phytochemical and Biological Investigation of an Indigenous Plant of Bangladesh, Gynura procumbens (Lour.) Merr.: Drug Discovery from Nature
inferred← citeshttps://doi.org/10.3390/molecules28227593openalex-snapshot
Molecular Hybridization of Alkaloids Using 1,2,3-Triazole-Based Click Chemistry
inferred← citeshttps://doi.org/10.3390/molecules29081807openalex-snapshot
Anticancer Effects of Abietane Diterpene 7α-Acetoxy-6β-hydroxyroyleanone from Plectranthus grandidentatus and Its Semi-Synthetic Analogs: An In Silico Computational Approach
inferred← citeshttps://doi.org/10.3390/ph15121471openalex-snapshot
Cyclooxygenase-2 (COX-2) as a Target of Anticancer Agents: A Review of Novel Synthesized Scaffolds Having Anticancer and COX-2 Inhibitory Potentialities
inferred← citeshttps://doi.org/10.3390/ph18081178openalex-snapshot
Machine Learning and Integrative Structural Dynamics Identify Potent ALK Inhibitors from Natural Compound Libraries
inferred← citeshttps://doi.org/10.3390/pharmaceutics17081002openalex-snapshot
In Silico ADME Methods Used in the Evaluation of Natural Products
inferred← citeshttps://doi.org/10.3390/scipharm94030061openalex-snapshot
Natural Products in Modern Drug Discovery: Advances, Challenges and Emerging Technologies
inferred← citeshttps://doi.org/10.3762/bjoc.18.92openalex-snapshot
Morita–Baylis–Hillman reaction of 3-formyl-9 H -pyrido[3,4- b ]indoles and fluorescence studies of the products
inferred← citeshttps://doi.org/10.3762/bjoc.22.81openalex-snapshot
Semisynthesis, characterisation, and antibacterial evaluation of a novel lecanoric acid-derived amide library
inferred← citeshttps://doi.org/10.3791/58195openalex-snapshot
Employing Pressurized Hot Water Extraction (PHWE) to Explore Natural Products Chemistry in the Undergraduate Laboratory
inferred← citeshttps://doi.org/10.3897/imafungus.16.142462openalex-snapshot
Fungi: Pioneers of chemical creativity – Techniques and strategies to uncover fungal chemistry
inferred← citeshttps://doi.org/10.3987/com-22-14626openalex-snapshot
Concise Semi-Synthesis of a Flavone Glycoside from Marine Angiosperm
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