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Natural Products as Alternative Choices for P-Glycoprotein (P-gp) Inhibition
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inferredcites →https://doi.org/10.1002/(sici)1099-1573(200003)14:2<139::aid-ptr608>3.0.co;2-8openalex-snapshot
The effect of reserpine, a modulator of multidrug efflux pumps, on the in vitro activity of tetracycline against clinical isolates of methicillin resistant Staphylococcus aureus (MRSA) possessing the tet(K) determinant
inferredcites →https://doi.org/10.1002/ajoc.201600462openalex-snapshot
Dihydro‐β‐agarofurans from the Australian Endemic Rainforest Plant Denhamia pittosporoides Inhibit Leucine Transport in Prostate Cancer Cells
inferredcites →https://doi.org/10.1002/bdd.593openalex-snapshot
Effects of oral kaempferol on the pharmacokinetics of tamoxifen and one of its metabolites, 4‐hydroxytamoxifen, after oral administration of tamoxifen to rats
inferredcites →https://doi.org/10.1002/cbdv.200790001openalex-snapshot
P‐Glycoprotein Inhibitory Activity of Two Phenolic Compounds, (−)‐Syringaresinol and Tricin from Sasa borealis
inferredcites →https://doi.org/10.1002/cncr.21227openalex-snapshot
Phase II study of tariquidar, a selective P‐glycoprotein inhibitor, in patients with chemotherapy‐resistant, advanced breast carcinoma
inferredcites →https://doi.org/10.1002/ijc.20505openalex-snapshot
Inhibition of leukemic cell growth by a novel anti‐cancer drug (GUT‐70) from calophyllum brasiliense that acts by induction of apoptosis
inferredcites →https://doi.org/10.1002/jcp.1040830114openalex-snapshot
Reduced permeability in CHO cells as a mechanism of resistance to colchicine
inferredcites →https://doi.org/10.1002/jps.10283openalex-snapshot
Effect of Flavonoids on MRP1-Mediated Transport in Panc-1 Cells
inferredcites →https://doi.org/10.1002/jps.20975openalex-snapshot
Grapefruit Juice–Drug Interactions: Grapefruit Juice and Its Components Inhibit P‐Glycoprotein (ABCB1) Mediated Transport of Talinolol in Caco‐2 Cells
inferredcites →https://doi.org/10.1002/ptr.1112openalex-snapshot
Activity of Zanthoxylum clava‐herculis extracts against multi‐drug resistant methicillin‐resistant Staphylococcus aureus (mdr‐MRSA)
inferredcites →https://doi.org/10.1002/ptr.1420openalex-snapshot
Antimycobacterial constituents from Juniperus procera, Ferula communis and Plumbago zeylanica and their in vitro synergistic activity with isonicotinic acid hydrazide
inferredcites →https://doi.org/10.1002/ptr.1711openalex-snapshot
Isopimaric acid from Pinus nigra shows activity against multidrug‐resistant and EMRSA strains of Staphylococcus aureus
inferredcites →https://doi.org/10.1002/ptr.2136openalex-snapshot
Antibacterial activity of two canthin‐6‐one alkaloids from Allium neapolitanum
inferredcites →https://doi.org/10.1002/ptr.2650openalex-snapshot
Potent modulation of P‐glycoprotein activity by naturally occurring phenylbutenoids fromZingiber cassumunar
inferredcites →https://doi.org/10.1002/ptr.2695openalex-snapshot
Modulation of drug resistance in staphylococcus aureus by a kaempferol glycoside from herissantia tiubae (malvaceae)
inferredcites →https://doi.org/10.1002/ptr.2781openalex-snapshot
Inhibition of P‐glycoprotein function by procyanidine on blood–brain barrier
inferredcites →https://doi.org/10.1002/ptr.2860openalex-snapshot
The beta‐carboline alkaloid harmine inhibits BCRP and can reverse resistance to the anticancer drugs mitoxantrone and camptothecin in breast cancer cells
inferredcites →https://doi.org/10.1002/ptr.2951openalex-snapshot
Modulation of P‐glycoprotein ATPase activity by some phytoconstituents
inferredcites →https://doi.org/10.1002/tox.20568openalex-snapshot
Hydrocinchonine, cinchonine, and quinidine potentiate paclitaxel‐induced cytotoxicity and apoptosis via multidrug resistance reversal in MES‐SA/DX5 uterine sarcoma cells
inferredcites →https://doi.org/10.1006/scbi.1997.0066openalex-snapshot
How does P-glycoprotein recognize its substrates?
inferredcites →https://doi.org/10.1007/bf00236389openalex-snapshot
Antimalarial activity of Artemisia annua flavonoids from whole plants and cell cultures
inferredcites →https://doi.org/10.1007/bf02968246openalex-snapshot
Aporphine alkaloids and their reversal activity of multidrug resistance (MDR) from the stems and rhizomes ofSinomenium acutum
inferredcites →https://doi.org/10.1007/bf02974076openalex-snapshot
Protoberberine alkaloids and their reversal activity of P-gp expressed multidrug resistance (MDR) from the rhizome ofCoptis japonica Makino
inferredcites →https://doi.org/10.1007/bf02977779openalex-snapshot
Isolation of limonoids and alkaloids fromPhellodendron amurense and their multidrug resistance (MDR) reversal activity
inferredcites →https://doi.org/10.1007/s00232-005-0792-1openalex-snapshot
Recent Progress in Understanding the Mechanism of P-Glycoprotein-mediated Drug Efflux
inferredcites →https://doi.org/10.1007/s00280-004-0914-yopenalex-snapshot
Inhibition of P-glycoprotein transport function and reversion of MDR1 multidrug resistance by cnidiadin
inferredcites →https://doi.org/10.1007/s00280-010-1396-8openalex-snapshot
Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects
inferredcites →https://doi.org/10.1007/s002800050592openalex-snapshot
Induction of apoptosis in multi-drug resistant (MDR) human glioblastoma cells by SN-38, a metabolite of the camptothecin derivative CPT-11
inferredcites →https://doi.org/10.1007/s00284-009-9416-9openalex-snapshot
Inhibitory and Resistance-Modifying Potential of Plant-Based Alkaloids Against Methicillin-Resistant Staphylococcus aureus (MRSA)
inferredcites →https://doi.org/10.1007/s00424-006-0126-xopenalex-snapshot
Structure and function of ABC transporters: the ATP switch provides flexible control
inferredcites →https://doi.org/10.1007/s11010-011-1064-2openalex-snapshot
The short-time treatment with curcumin sufficiently decreases cell viability, induces apoptosis and copper enhances these effects in multidrug-resistant K562/A02 cells
inferredcites →https://doi.org/10.1007/s11010-015-2339-9openalex-snapshot
Glaucine inhibits breast cancer cell migration and invasion by inhibiting MMP-9 gene expression through the suppression of NF-κB activation
inferredcites →https://doi.org/10.1007/s11095-011-0368-yopenalex-snapshot
5,7-Dimethoxyflavone and Multiple Flavonoids in Combination Alter the ABCG2-Mediated Tissue Distribution of Mitoxantrone in Mice
inferredcites →https://doi.org/10.1007/s11101-009-9126-8openalex-snapshot
Jatrophane diterpenes from Euphorbia spp. as modulators of multidrug resistance in cancer therapy
inferredcites →https://doi.org/10.1007/s12038-010-0065-8openalex-snapshot
Antimycobacterial activity of two natural alkaloids, vasicine acetate and 2-acetyl benzylamine, isolated from Indian shrub Adhatoda vasica Ness. leaves
inferredcites →https://doi.org/10.1007/s12272-011-0217-xopenalex-snapshot
Effects of myricetin on the bioavailability of doxorubicin for oral drug delivery in Rats: Possible role of CYP3A4 and P-glycoprotein inhibition by myricetin
inferredcites →https://doi.org/10.1007/s12272-011-1117-9openalex-snapshot
Effects of baicalein on the pharmacokinetics of tamoxifen and its main metabolite, 4-hydroxytamoxifen, in rats: Possible role of cytochrome p450 3A4 and P-glycoprotein inhibition by baicalein
inferredcites →https://doi.org/10.1016/0006-2952(94)90067-1openalex-snapshot
P-Glycoprotein overexpression in methotrexate-resistant Leishmania tropica
inferredcites →https://doi.org/10.1016/0006-2952(94)90209-7openalex-snapshot
Expression and function of multidrug resistance P-glycoprotein in a cultured natural killer cell-rich population revealed by MRK16 monoclonal antibody and AHC-52
inferredcites →https://doi.org/10.1016/0006-2952(94)90568-1openalex-snapshot
Modulation of adriamycin® accumulation and efflux by flavonoids in HCT-15 colon cells
inferredcites →https://doi.org/10.1016/0006-2952(95)00115-gopenalex-snapshot
Novel dithiane analogues of tiapamil with high activity to overcome multidrug resistance in vitro
inferredcites →https://doi.org/10.1016/0092-8674(91)90141-kopenalex-snapshot
Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells
inferredcites →https://doi.org/10.1016/0145-2126(93)90159-iopenalex-snapshot
Detection of P glycoprotein activity on normal and leukemic CD34+ cells
inferredcites →https://doi.org/10.1016/0166-6851(93)90252-sopenalex-snapshot
Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand
inferredcites →https://doi.org/10.1016/0304-3835(93)90103-gopenalex-snapshot
A marine natural product, patellamide D, reverses multidrug resistance in a human leukemic cell line
inferredcites →https://doi.org/10.1016/0378-1119(95)00533-copenalex-snapshot
Increase in mRNA of multiple Eh pgp genes encoding P-glycoprotein homologues in emetine-resistant Entamoeba histolytica parasites
inferredcites →https://doi.org/10.1016/0968-0004(92)90419-aopenalex-snapshot
Is the multidrug transporter a flippase?
inferredcites →https://doi.org/10.1016/j.antiviral.2016.01.001openalex-snapshot
Characterization of the inhibitory effect of an extract of Prunella vulgaris on Ebola virus glycoprotein (GP)-mediated virus entry and infection
inferredcites →https://doi.org/10.1016/j.bbagen.2016.04.007openalex-snapshot
Rhamnetin induces sensitization of hepatocellular carcinoma cells to a small molecular kinase inhibitor or chemotherapeutic agents
inferredcites →https://doi.org/10.1016/j.bbrc.2004.03.040openalex-snapshot
Interaction of the breast cancer resistance protein with plant polyphenols
inferredcites →https://doi.org/10.1016/j.bbrc.2004.12.081openalex-snapshot
Effects of dietary chemopreventive phytochemicals on P-glycoprotein function
inferredcites →https://doi.org/10.1016/j.bbrc.2005.01.134openalex-snapshot
Do drug substrates enter the common drug-binding pocket of P-glycoprotein through “gates”?
inferredcites →https://doi.org/10.1016/j.bcp.2004.11.002openalex-snapshot
Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2
inferredcites →https://doi.org/10.1016/j.bcp.2005.04.001openalex-snapshot
Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of α,β-unsaturated carbonyl compounds
inferredcites →https://doi.org/10.1016/j.bcp.2005.10.021openalex-snapshot
Efflux systems in bacterial pathogens: An opportunity for therapeutic intervention? An industry view
inferredcites →https://doi.org/10.1016/j.bcp.2005.12.008openalex-snapshot
Practical applications and feasibility of efflux pump inhibitors in the clinic—A vision for applied use
inferredcites →https://doi.org/10.1016/j.bcp.2006.06.036openalex-snapshot
Gomisin A alters substrate interaction and reverses P-glycoprotein-mediated multidrug resistance in HepG2-DR cells
inferredcites →https://doi.org/10.1016/j.biopha.2008.07.089openalex-snapshot
Reversal effect of resveratrol on multidrug resistance in KBv200 cell line
inferredcites →https://doi.org/10.1016/j.biopha.2015.01.007openalex-snapshot
Effects of natural nuclear factor-kappa B inhibitors on anticancer drug efflux transporter human P-glycoprotein
inferredcites →https://doi.org/10.1016/j.bmc.2006.09.028openalex-snapshot
Apoptosis induction and modulation of P-glycoprotein mediated multidrug resistance by new macrocyclic lathyrane-type diterpenoids
inferredcites →https://doi.org/10.1016/j.bmc.2007.07.020openalex-snapshot
Natural triterpenoids from Cecropia lyratiloba are cytotoxic to both sensitive and multidrug resistant leukemia cell lines
inferredcites →https://doi.org/10.1016/j.bmc.2008.08.071openalex-snapshot
Synergistic interaction between p-glycoprotein modulators and epirubicine on resistant cancer cells
inferredcites →https://doi.org/10.1016/j.bmc.2009.08.020openalex-snapshot
New potent P-glycoprotein modulators with the cucurbitane scaffold and their synergistic interaction with doxorubicin on resistant cancer cells
inferredcites →https://doi.org/10.1016/j.bmc.2011.03.055openalex-snapshot
New 29-nor-cycloartanes with a 3,4-seco- and a novel 2,3-seco-structure from the leaves of Sinocalycanthus chinensis
inferredcites →https://doi.org/10.1016/j.bmc.2013.12.022openalex-snapshot
Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication
inferredcites →https://doi.org/10.1016/j.bmcl.2004.06.074openalex-snapshot
Cytotoxic effects and reversal of multidrug resistance by ibogan and related indole alkaloids
inferredcites →https://doi.org/10.1016/j.bmcl.2006.12.059openalex-snapshot
N-Caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors
inferredcites →https://doi.org/10.1016/j.drudis.2007.06.004openalex-snapshot
Identification of drugs that interact with herbs in drug development
inferredcites →https://doi.org/10.1016/j.ejphar.2009.09.040openalex-snapshot
Inhibition of P-glycoprotein activity by limonin and other secondary metabolites from Citrus species in human colon and leukaemia cell lines
inferredcites →https://doi.org/10.1016/j.ejphar.2010.06.069openalex-snapshot
8-Prenylnaringenin is an inhibitor of multidrug resistance-associated transporters, P-glycoprotein and MRP1
inferredcites →https://doi.org/10.1016/j.ejps.2005.03.001openalex-snapshot
Modulation of drug transport by selected flavonoids: Involvement of P-gp and OCT?
inferredcites →https://doi.org/10.1016/j.etp.2006.01.008openalex-snapshot
Sanguinarine overcomes P-glycoprotein-mediated multidrug-resistance via induction of apoptosis and oncosis in CEM-VLB 1000 cells
inferredcites →https://doi.org/10.1016/j.fct.2006.07.003openalex-snapshot
Inhibition of P-glycoprotein-mediated transport by terpenoids contained in herbal medicines and natural products
inferredcites →https://doi.org/10.1016/j.fct.2011.11.008openalex-snapshot
Anti-proliferative activity and suppression of P-glycoprotein by (−)-antofine, a natural phenanthroindolizidine alkaloid, in paclitaxel-resistant human lung cancer cells
inferredcites →https://doi.org/10.1016/j.fitote.2008.09.010openalex-snapshot
Selective modulation of P-glycoprotein activity by steroidal saponines from Paris polyphylla
inferredcites →https://doi.org/10.1016/j.fitote.2011.01.015openalex-snapshot
Alkaloids derived from genus Veratrum and Peganum of Mongolian origin as multidrug resistance inhibitors of cancer cells
inferredcites →https://doi.org/10.1016/j.fitote.2015.03.025openalex-snapshot
Reversal of P-glycoprotein-mediated multidrug resistance in MCF-7/Adr cancer cells by sesquiterpene coumarins
inferredcites →https://doi.org/10.1016/j.foodchem.2012.09.059openalex-snapshot
An isoquinoline alkaloid from the Chinese herbal plant Corydalis yanhusuo W.T. Wang inhibits P-glycoprotein and multidrug resistance-associate protein 1
inferredcites →https://doi.org/10.1016/j.ijantimicag.2010.09.011openalex-snapshot
Inhibition of efflux pumps in meticillin-resistant Staphylococcus aureus and Enterococcus faecalis resistant strains by triterpenoids from Momordica balsamina
inferredcites →https://doi.org/10.1016/j.lfs.2004.06.015openalex-snapshot
Effects of grapefruit juice on the multidrug transporter P-glycoprotein in the human proximal tubular cell line HK-2
inferredcites →https://doi.org/10.1016/j.lfs.2005.12.009openalex-snapshot
Evidence-based drug–herbal interactions
inferredcites →https://doi.org/10.1016/j.molmed.2005.06.006openalex-snapshot
Inhibitors of efflux pumps in Gram-negative bacteria
inferredcites →https://doi.org/10.1016/j.pharep.2015.08.018openalex-snapshot
Effect of resveratrol on the pharmacokinetics of fexofenadine in rats: Involvement of P-glycoprotein inhibition
inferredcites →https://doi.org/10.1016/j.phrs.2006.10.007openalex-snapshot
A primer on the mechanics of P-glycoprotein the multidrug transporter
inferredcites →https://doi.org/10.1016/j.phymed.2007.11.028openalex-snapshot
Lobeline, a piperidine alkaloid from Lobelia can reverse P-gp dependent multidrug resistance in tumor cells
inferredcites →https://doi.org/10.1016/j.phymed.2010.07.014openalex-snapshot
Stemona alkaloids, from traditional Thai medicine, increase chemosensitivity via P-glycoprotein-mediated multidrug resistance
inferredcites →https://doi.org/10.1016/j.phymed.2013.07.019openalex-snapshot
Influence of combinations of digitonin with selected phenolics, terpenoids, and alkaloids on the expression and activity of P-glycoprotein in leukaemia and colon cancer cells
inferredcites →https://doi.org/10.1016/j.phymed.2014.04.029openalex-snapshot
Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania tetrandra can reverse multidrug resistance by inhibiting P-glycoprotein activity in multidrug resistant human cancer cells
inferredcites →https://doi.org/10.1016/j.phymed.2015.01.002openalex-snapshot
Cytotoxicity of the indole alkaloid reserpine from Rauwolfia serpentina against drug-resistant tumor cells
inferredcites →https://doi.org/10.1016/j.phymed.2015.02.003openalex-snapshot
Enhancing activity of antibiotics against Staphylococcus aureus: Zanthoxylum capense constituents and derivatives
inferredcites →https://doi.org/10.1016/j.taap.2005.04.001openalex-snapshot
Inhibition of P-glycoprotein-mediated transport by extracts of and monoterpenoids contained in Zanthoxyli Fructus
inferredcites →https://doi.org/10.1016/j.taap.2008.02.026openalex-snapshot
In vitro and in vivo evaluation of the effects of piperine on P-gp function and expression
inferredcites →https://doi.org/10.1016/j.taap.2013.12.015openalex-snapshot
Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: Herb–drug interactions mediated via P-gp
inferredcites →https://doi.org/10.1016/j.taap.2013.12.018openalex-snapshot
Optimization of irinotecan chronotherapy with P-glycoprotein inhibition
inferredcites →https://doi.org/10.1016/j.tet.2003.07.020openalex-snapshot
Kendarimide A, a novel peptide reversing P-glycoprotein-mediated multidrug resistance in tumor cells, from a marine sponge of Haliclona sp.
inferredcites →https://doi.org/10.1016/j.tiv.2011.09.023openalex-snapshot
Inhibitory effects of limonin on six human cytochrome P450 enzymes and P-glycoprotein in vitro
inferredcites →https://doi.org/10.1016/s0006-291x(02)00755-6openalex-snapshot
Reversal of P-glycoprotein-mediated multidrug resistance by 5,6,7,3′,4′-pentamethoxyflavone (Sinensetin)
inferredcites →https://doi.org/10.1016/s0006-2952(02)00902-4openalex-snapshot
The alkaloid sanguinarine is effective against multidrug resistance in human cervical cells via bimodal cell death
inferredcites →https://doi.org/10.1016/s0006-2952(98)00107-5openalex-snapshot
PKC-independent modulation of multidrug resistance in cells with mutant (V185) but not wild-type (G185) p-glycoprotein by bryostatin 1
inferredcites →https://doi.org/10.1016/s0009-2797(98)00092-1openalex-snapshot
The effect of the flavonoids, quercetin, myricetin and epicatechin on the growth and enzyme activities of MCF7 human breast cancer cells
inferredcites →https://doi.org/10.1016/s0014-2999(00)00180-1openalex-snapshot
Effect of bioflavonoids on vincristine transport across blood–brain barrier
inferredcites →https://doi.org/10.1016/s0014-5793(03)01085-8openalex-snapshot
Multidrug resistance ABC transporters
inferredcites →https://doi.org/10.1016/s0026-895x(25)08534-7openalex-snapshot
Welwitindolinone analogues that reverse P-glycoprotein-mediated multiple drug resistance.
inferredcites →https://doi.org/10.1016/s0040-4039(98)01336-7openalex-snapshot
Agosterol A, a novel polyhydroxylated sterol acetate reversing multidrug resistance from a marine sponge of Spongia sp.
inferredcites →https://doi.org/10.1016/s0065-2423(08)60332-7openalex-snapshot
Multidrug Resistance in the Laboratory and Clinic
inferredcites →https://doi.org/10.1016/s0092-8674(00)81370-7openalex-snapshot
MDR1 P-Glycoprotein Is a Lipid Translocase of Broad Specificity, While MDR3 P-Glycoprotein Specifically Translocates Phosphatidylcholine
inferredcites →https://doi.org/10.1016/s0167-4889(01)00175-6openalex-snapshot
Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols
inferredcites →https://doi.org/10.1016/s0304-3835(00)00549-8openalex-snapshot
Inhibition of P-glycoprotein by orange juice components, polymethoxyflavones in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells
inferredcites →https://doi.org/10.1016/s0304-3835(02)00593-1openalex-snapshot
Pentacyclic triterpenes from Chrysobalanaceae species: cytotoxicity on multidrug resistant and sensitive leukemia cell lines
inferredcites →https://doi.org/10.1016/s0923-2508(01)01193-7openalex-snapshot
ABC transporters: physiology, structure and mechanism – an overview
inferredcites →https://doi.org/10.1016/s0924-8579(03)00085-2openalex-snapshot
Berberis aetnensis C. Presl. extracts: antimicrobial properties and interaction with ciprofloxacin
inferredcites →https://doi.org/10.1016/s0924-8579(03)00203-6openalex-snapshot
ABC-transporters: implications on drug resistance from microorganisms to human cancers
inferredcites →https://doi.org/10.1016/s0928-0987(00)00114-7openalex-snapshot
Multidrug resistance (MDR) in cancer
inferredcites →https://doi.org/10.1016/s0960-894x(03)00294-4openalex-snapshot
Multidrug resistance reversal activity of key ningalin analogues
inferredcites →https://doi.org/10.1016/s0960-894x(03)00316-0openalex-snapshot
Polyacylated neohesperidosides From Geranium caespitosum: bacterial multidrug resistance pump inhibitors
inferredcites →https://doi.org/10.1016/s0960-894x(98)00486-7openalex-snapshot
Reversal of multidrug resistance (MDR) by aspidofractinine-type indole alkaloids
inferredcites →https://doi.org/10.1016/s0966-842x(01)02175-8openalex-snapshot
The emergence and evolution of methicillin-resistant Staphylococcus aureus
inferredcites →https://doi.org/10.1016/s1043-6618(03)00158-0openalex-snapshot
P-glycoprotein inhibitors and their screening: a perspective from bioavailability enhancement
inferredcites →https://doi.org/10.1017/s1461145709990848openalex-snapshot
Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)
inferredcites →https://doi.org/10.1021/bi9808823openalex-snapshot
Structural Flexibility of the Linker Region of Human P-Glycoprotein Permits ATP Hydrolysis and Drug Transport
inferredcites →https://doi.org/10.1021/bi992931xopenalex-snapshot
Analysis of the Properties of the N-Terminal Nucleotide-Binding Domain of Human P-Glycoprotein
inferredcites →https://doi.org/10.1021/jf063138vopenalex-snapshot
Polymethoxylated Flavones and Other Phenolic Derivates from Citrus in Their Inhibitory Effects on P-Glycoprotein-Mediated Transport of Talinolol in Caco-2 Cells
inferredcites →https://doi.org/10.1021/jf0728451openalex-snapshot
Effect of Grapefruit Juice, Naringin, Naringenin, and Bergamottin on the Intestinal Carrier-Mediated Transport of Talinolol in Rats
inferredcites →https://doi.org/10.1021/jm0309699openalex-snapshot
SAR Studies of Dihydro-β-agarofuran Sesquiterpenes as Inhibitors of the Multidrug-Resistance Phenotype in a Leishmania tropica Line Overexpressing a P-Glycoprotein-Like Transporter
inferredcites →https://doi.org/10.1021/jm301441wopenalex-snapshot
Enhancing Macrocyclic Diterpenes as Multidrug-Resistance Reversers: Structure–Activity Studies on Jolkinol D Derivatives
inferredcites →https://doi.org/10.1021/jo00103a011openalex-snapshot
Hapalosin, a Cyanobacterial Cyclic Depsipeptide with Multidrug-Resistance Reversing Activity
inferredcites →https://doi.org/10.1021/jo00302a006openalex-snapshot
Antitumor tetrahydroisoquinoline alkaloids from the colonial ascidian Ecteinascidia turbinata
inferredcites →https://doi.org/10.1021/np050227dopenalex-snapshot
Polyacylated Oligosaccharides from Medicinal Mexican Morning Glory Species as Antibacterials and Inhibitors of Multidrug Resistance inStaphylococcus aureus
inferredcites →https://doi.org/10.1021/np050554lopenalex-snapshot
Aegicerin, the First Oleanane Triterpene with Wide-Ranging Antimycobacterial Activity, Isolated from Clavija procera
inferredcites →https://doi.org/10.1021/np058057sopenalex-snapshot
Metabolites of the “Smoke Tree”, Dalea spinosa, Potentiate Antibiotic Activity against Multidrug-Resistant Staphylococcus aureus
inferredcites →https://doi.org/10.1021/np060046ropenalex-snapshot
Euphoportlandols A and B, Tetracylic Diterpene Polyesters from Euphorbia p ortlandica and Their Anti-MDR Effects in Cancer Cells
inferredcites →https://doi.org/10.1021/np0605889openalex-snapshot
Reversal of P-Glycoprotein-Mediated Multidrug Resistance by Sipholane Triterpenoids
inferredcites →https://doi.org/10.1021/np070458fopenalex-snapshot
Tenacigenin B Derivatives Reverse P-Glycoprotein-Mediated Multidrug Resistance inHepG2/Dox Cells
inferredcites →https://doi.org/10.1021/np3004003openalex-snapshot
Jatrophane Diterpenes fromEuphorbia melliferaand Their Activity as P-Glycoprotein Modulators on Multidrug-Resistant Mouse Lymphoma and Human Colon Adenocarcinoma Cells
inferredcites →https://doi.org/10.1021/np50113a007openalex-snapshot
Indole Alkaloids from Peschiera laeta That Enhance Vinblastine-Mediated Cytotoxicity with Multi-drug-Resistant Cells
inferredcites →https://doi.org/10.1021/np900091yopenalex-snapshot
Sipholane Triterpenoids: Chemistry, Reversal of ABCB1/P-Glycoprotein-Mediated Multidrug Resistance, and Pharmacophore Modeling
inferredcites →https://doi.org/10.1021/np9802872openalex-snapshot
New Cyclic Peptides from the AscidianLissoclinumpatella
inferredcites →https://doi.org/10.1021/ol200904vopenalex-snapshot
Nocardioazines: A Novel Bridged Diketopiperazine Scaffold from a Marine-Derived Bacterium Inhibits P-Glycoprotein
inferredcites →https://doi.org/10.1021/ol801895yopenalex-snapshot
A New Total Synthesis of Patellamide A
inferredcites →https://doi.org/10.1038/25393openalex-snapshot
Crystal structure of the ATP-binding subunit of an ABC transporter
inferredcites →https://doi.org/10.1038/bjc.1993.177openalex-snapshot
Constitutive expression of multidrug resistance in human colorectal tumours and cell lines
inferredcites →https://doi.org/10.1038/bjc.1996.421openalex-snapshot
Polyaromatic alkaloids from marine invertebrates as cytotoxic compounds and inhibitors of multidrug resistance caused by P-glycoprotein
inferredcites →https://doi.org/10.1038/nrd2200openalex-snapshot
Waltzing transporters and 'the dance macabre' between humans and bacteria
inferredcites →https://doi.org/10.1038/sj.bjp.0703433openalex-snapshot
Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco‐2 cells and on the activity of cytochrome P450 3A4
inferredcites →https://doi.org/10.1038/sj.leu.2401945openalex-snapshot
Phase I study of cinchonine, a multidrug resistance reversing agent, combined with the CHVP regimen in relapsed and refractory lymphoproliferative syndromes
inferredcites →https://doi.org/10.1039/b915678jopenalex-snapshot
Novel dihydro-β-agarofuran sesquiterpenes as potent modulators of human P-glycoprotein dependent multidrug resistance
inferredcites →https://doi.org/10.1046/j.1365-2125.1999.00052.xopenalex-snapshot
Inhibition of the CYP3A4‐mediated metabolism and P‐glycoprotein‐mediated transport of the HIV‐1 protease inhibitor saquinavir by grapefruit juice components
inferredcites →https://doi.org/10.1055/s-0029-1234258openalex-snapshot
Inhibition of P-glycoprotein at the blood brain barrier by phytochemicals derived from traditional Chinese medicine
inferredcites →https://doi.org/10.1055/s-0030-1270987openalex-snapshot
Farnesiferol A fromFerula persicaand Galbanic Acid fromFerula szowitsianaInhibit P-Glycoprotein-Mediated Rhodamine Efflux in Breast Cancer Cell Lines
inferredcites →https://doi.org/10.1055/s-0032-1327896openalex-snapshot
Phytochemical Analysis and Cytotoxicity Towards Multidrug-Resistant Leukemia Cells of Essential Oils Derived from Lebanese Medicinal Plants
inferredcites →https://doi.org/10.1055/s-1999-13991openalex-snapshot
Reversal of Multidrug Resistance by Kopsiflorine Isolated from Kopsia dasyrachis
inferredcites →https://doi.org/10.1055/s-2002-36347openalex-snapshot
Two Flavonols fromArtemisa annuawhich Potentiate the Activity of Berberine and Norfloxacin Against a Resistant Strain ofStaphylococcus aureus
inferredcites →https://doi.org/10.1055/s-2003-38483openalex-snapshot
Reversal of P-Glycoprotein-Mediated Multidrug Resistance by Protopanaxatriol Ginsenosides from Korean Red Ginseng
inferredcites →https://doi.org/10.1055/s-2006-931574openalex-snapshot
Conferone from Ferula schtschurowskiana Enhances Vinblastine Cytotoxicity in MDCK-MDR1 Cells by Competitively Inhibiting P-Glycoprotein Transport
inferredcites →https://doi.org/10.1055/s-2008-1074518openalex-snapshot
Phytochemicals for Bacterial Resistance - Strengths, Weaknesses and Opportunities
inferredcites →https://doi.org/10.1073/pnas.84.21.7735openalex-snapshot
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.
inferredcites →https://doi.org/10.1073/pnas.86.2.695openalex-snapshot
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.
inferredcites →https://doi.org/10.1073/pnas.87.1.152openalex-snapshot
Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies.
inferredcites →https://doi.org/10.1073/pnas.95.14.8369openalex-snapshot
Reversal of anticancer multidrug resistance by the ardeemins
inferredcites →https://doi.org/10.1074/jbc.m311825200openalex-snapshot
Disulfide Cross-linking Analysis Shows That Transmembrane Segments 5 and 8 of Human P-glycoprotein Are Close Together on the Cytoplasmic Side of the Membrane
inferredcites →https://doi.org/10.1074/jbc.m311964200openalex-snapshot
Synergy between Conserved ABC Signature Ser Residues in P-glycoprotein Catalysis
inferredcites →https://doi.org/10.1074/jbc.m400229200openalex-snapshot
Val133 and Cys137 in Transmembrane Segment 2 Are Close to Arg935 and Gly939 in Transmembrane Segment 11 of Human P-glycoprotein
inferredcites →https://doi.org/10.1074/jbc.m411483200openalex-snapshot
The Dileucine Motif at the COOH Terminus of Human Multidrug Resistance P-glycoprotein Is Important for Folding but Not Activity
inferredcites →https://doi.org/10.1074/jbc.m909002199openalex-snapshot
MDR3 P-glycoprotein, a Phosphatidylcholine Translocase, Transports Several Cytotoxic Drugs and Directly Interacts with Drugs as Judged by Interference with Nucleotide Trapping
inferredcites →https://doi.org/10.1080/10286020.2011.620393openalex-snapshot
Uptake characteristics of pinocembrin and its effect on p-glycoprotein at the blood–brain barrier inin vitrocell experiments
inferredcites →https://doi.org/10.1080/14786419.2014.994210openalex-snapshot
Curcuma ecalcarata – new natural source of pinocembrin and piperitenone
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Transfer of Cationic Antibacterial Agents Berberine, Palmatine, and Benzalkonium Through Bimolecular Planar Phospholipid Film and Staphylococcus aureus Membrane
inferredcites →https://doi.org/10.1093/jac/dkl460openalex-snapshot
Bacterial efflux pump inhibitors from natural sources
inferredcites →https://doi.org/10.1093/jac/dkn178openalex-snapshot
Plant phenolic compounds as ethidium bromide efflux inhibitors in Mycobacterium smegmatis
inferredcites →https://doi.org/10.1093/jac/dkq079openalex-snapshot
Natural and synthetic compounds such as trimethoprim behave as inhibitors of efflux in Gram-negative bacteria
inferredcites →https://doi.org/10.1093/jac/dkq186openalex-snapshot
Piperine as an inhibitor of Rv1258c, a putative multidrug efflux pump of Mycobacterium tuberculosis
inferredcites →https://doi.org/10.1093/jnci/81.15.1144openalex-snapshot
MDR1 Gene Expression in Lung Cancer
inferredcites →https://doi.org/10.1093/jnci/81.18.1401openalex-snapshot
Correlation of MDR1 Gene Expression With Chemotherapy in Neuroblastoma
inferredcites →https://doi.org/10.1097/00001813-199803000-00008openalex-snapshot
The bis benzylisoquinoline alkaloids, tetrandine and fangchinoline, enhance the cytotoxicity of multidrug resistance-related drugs via modulation of P-glycoprotein
inferredcites →https://doi.org/10.1111/cbdd.12103openalex-snapshot
Antibacterial and Synergy of Clavine Alkaloid Lysergol and its Derivatives Against Nalidixic Acid‐Resistant E scherichia coli
inferredcites →https://doi.org/10.1111/j.1349-7006.2005.00057.xopenalex-snapshot
Cepharanthine potently enhances the sensitivity of anticancer agents in K562 cells
inferredcites →https://doi.org/10.1111/j.1365-2141.1991.tb04378.xopenalex-snapshot
Expression of the multidrug resistance gene product (P‐glycoprotein) in myelodysplasia is associated with a stem cell phenotype
inferredcites →https://doi.org/10.1111/j.1365-2672.2007.03617.xopenalex-snapshot
Plagiochin E, a botanic-derived phenolic compound, reverses fungal resistance to fluconazole relating to the efflux pump
inferredcites →https://doi.org/10.1111/j.1742-7843.2012.00921.xopenalex-snapshot
Gambogic Acid as a Non‐Competitive Inhibitor of ATP‐Binding Cassette Transporter B1 Reverses the Multidrug Resistance of Human Epithelial Cancers by Promoting ATP‐Binding Cassette Transporter B1 Protein Degradation
inferredcites →https://doi.org/10.1111/j.1745-7254.2008.00884.xopenalex-snapshot
Intra-herb pharmacokinetics interaction between quercetin and isorhamentin
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Reversal of P-glycoprotein-mediated multidrug resistance of human hepatic cancer cells by Astragaloside II
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APPLICATION OF COMPARTMENTAL MODELING TO AN EXAMINATION OF IN VITRO INTESTINAL PERMEABILITY DATA: ASSESSING THE IMPACT OF TISSUE UPTAKE, P-GLYCOPROTEIN, AND CYP3A
inferredcites →https://doi.org/10.1124/jpet.102.037549openalex-snapshot
Interaction of Cytochrome P450 3A Inhibitors with P-Glycoprotein
inferredcites →https://doi.org/10.1124/jpet.102.044412openalex-snapshot
Effects of the Flavonoids Biochanin A, Morin, Phloretin, and Silymarin on P-Glycoprotein-Mediated Transport
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Characterization of P-glycoprotein Inhibition by Major Cannabinoids from Marijuana
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The Microtubule-Stabilizing Agent Discodermolide Competitively Inhibits the Binding of Paclitaxel (Taxol) to Tubulin Polymers, Enhances Tubulin Nucleation Reactions More Potently than Paclitaxel, and Inhibits the Growth of Paclitaxel-Resistant Cells
inferredcites →https://doi.org/10.1124/mol.65.5.1208openalex-snapshot
Flavonoids Are Inhibitors of Breast Cancer Resistance Protein (ABCG2)-Mediated Transport
inferredcites →https://doi.org/10.1128/aac.00216-07openalex-snapshot
The Phenolic Diterpene Totarol Inhibits Multidrug Efflux Pump Activity in Staphylococcus aureus
inferredcites →https://doi.org/10.1128/aac.01533-09openalex-snapshot
Efflux Pumps Are Involved in the Defense of Gram-Negative Bacteria against the Natural Products Isobavachalcone and Diospyrone
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Influence of P-Glycoprotein Inhibitors on Accumulationof Macrolides in J774 MurineMacrophages
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Acquired Bacitracin Resistance in Enterococcus faecalis Is Mediated by an ABC Transporter and a Novel Regulatory Protein, BcrR
inferredcites →https://doi.org/10.1128/mmbr.62.1.1-34.1998openalex-snapshot
Major Facilitator Superfamily
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BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTER
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Biological Activities and Pharmacokinetics of Praeruptorins from Peucedanum Species: A Systematic Review
inferredcites →https://doi.org/10.1158/0008-5472.can-04-0078openalex-snapshot
Phytoestrogens/Flavonoids Reverse Breast Cancer Resistance Protein/ABCG2-Mediated Multidrug Resistance
inferredcites →https://doi.org/10.1158/0008-5472.can-08-2037openalex-snapshot
The Taccalonolides: Microtubule Stabilizers That Circumvent Clinically Relevant Taxane Resistance Mechanisms
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A Phase I, Randomized, Open-Label, Parallel-Cohort, Dose-Finding Study of Elacridar (GF120918) and Oral Topotecan in Cancer Patients
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Inhibition of ABCG2-mediated transport by protein kinase inhibitors with a bisindolylmaleimide or indolocarbazole structure
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Multidrug resistance (mdr1) gene expression in adult acute leukemias: correlations with treatment outcome and in vitro drug sensitivity
showing the first 200 of 238 · page through all 238
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Emerging Non-Traditional Approaches to Combat Antibiotic Resistance
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Role of natural P-gp inhibitor in the effective delivery for chemotherapeutic agents
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Six Phthalides as Potent Modulators of the Blood Tumor Barrier Increase the Transmembrane Transport of Compatible Compounds Via Transcellular and Paracellular Pathways
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Reversal of multidrug resistance by amphiphilic morning glory resin glycosides in bacterial pathogens and human cancer cells
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Investigating the Effect of Satureja khuzestanica Essential oil on MDR1 Gene Expression in Leishmania major
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Nanoparticles beyond the blood-brain barrier for glioblastoma
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Cinnamophilin overcomes cancer multi-drug resistance via allosterically modulating human P-glycoprotein on both drug binding sites and ATPase binding sites
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Novel application of rhein and its prodrug diacerein for reversing cancer-related multidrug resistance through the dual inhibition of P-glycoprotein efflux and STAT3-mediated P-glycoprotein expression
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Effects of β-lapachone and β-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata
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Dual-modulation of nutrient-transporter axis and functionalized carriers: A paradigm shift for precision oral vitamin D delivery
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Natural medicinal compounds target signal transduction pathways to overcome ABC drug efflux transporter-mediated multidrug resistance in cancer
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Human variability in influx and efflux transporters in relation to uncertainty factors for chemical risk assessment
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Gastrointestinal-controlled dipotassium glycyrrhizinate self-assembly particles enhance fucoxanthin oral bioavailability for improved visual sensitivity
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P-gp inhibition and enhanced oral bioavailability of amikacin Sulfate: A novel approach using Thiolated Chito-PEGylated Lipidic Hybrids
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In Silico Studies of Bioactive Compounds from Alpinia Officinarum as Inhibitors of Zika Virus Protease
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Tailoring of P-glycoprotein for effective transportation of actives across blood-brain-barrier
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Nanoplatform-based natural products co-delivery system to surmount cancer multidrug-resistant
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Shedding light on interaction of so called inactive ingredients (excipients) with permeability-glycoprotein
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Importance of P-gp inhibitors and nanoengineered approaches for effective delivery of anti-retroviral drugs across barriers in HIV management
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Plant-derived exosome-like nanoparticles remodel the tumor microenvironment for cancer therapy
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Cytochrome P450 inhibition activities of non-standardized botanical products
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Effects of kefir on doxorubicin-induced multidrug resistance in human colorectal cancer cells
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Protecting future antimalarials from the trap of resistance: Lessons from artemisinin-based combination therapy (ACT) failures
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Himatanthus bracteatus stem bark ethanolic extract obtained by sequential pressurized liquid extraction: Chromatographic characterization and profiling of cytotoxic, antitumoral and immunopharmacological properties
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The effects of drug transporters on the efficacy of methotrexate in the treatment of rheumatoid arthritis
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Nanocomposites for bone tissue engineering application
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Chemoprevention and therapeutic role of essential oils and phenolic compounds: Modeling tumor microenvironment in glioblastoma
inferred← citeshttps://doi.org/10.1016/j.phyplu.2026.101001openalex-snapshot
Orally active bi-herbal combo of Annickia affinis and Nauclea pobeguinii displays promising potency against chloroquine resistant Plasmodium falciparum
inferred← citeshttps://doi.org/10.1016/j.sciaf.2021.e01022openalex-snapshot
Palmatine sensitizes chemoresistant triple negative breast cancer cells via efflux inhibition of multidrug resistant protein 1.
inferred← citeshttps://doi.org/10.1016/j.tifs.2024.104473openalex-snapshot
Construction of efficient carotenoid delivery vehicles based on the intestinal epithelial transport pathway: Current applications and future trends
inferred← citeshttps://doi.org/10.1016/j.yexcr.2024.114153openalex-snapshot
Solasodine targets NF-κB signaling to overcome P-glycoprotein mediated multidrug resistance in cancer
inferred← citeshttps://doi.org/10.1016/s1875-5364(25)60815-6openalex-snapshot
Progress on the functions and mechanisms of natural products in anti-glioma therapy
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.8b00335openalex-snapshot
Discovery of 5-Cyano-6-phenylpyrimidin Derivatives Containing an Acylurea Moiety as Orally Bioavailable Reversal Agents against P-Glycoprotein-Mediated Mutidrug Resistance
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.9b01181openalex-snapshot
Chrysosporazines F–M: P‑Glycoprotein Inhibitory Phenylpropanoid Piperazines from an Australian Marine Fish Derived Fungus, Chrysosporium sp. CMB-F294
inferred← citeshttps://doi.org/10.1021/acsomega.3c06202openalex-snapshot
A Novel 3-meta-Pyridine-1,2,4-oxadiazole Derivative of Glycyrrhetinic Acid as a Safe and Promising Candidate for Overcoming P-Glycoprotein-Mediated Multidrug Resistance in Tumor Cells
inferred← citeshttps://doi.org/10.1021/acsomega.5c07564openalex-snapshot
Evaluation of the Pharmacokinetic Interactions of Maytenus ilicifolia Mart. ex Reiss Extracts on Drug Intestinal Permeability and Hepatic Metabolism
inferred← citeshttps://doi.org/10.1038/s41467-024-48461-4openalex-snapshot
Regulation of cerebral blood flow boosts precise brain targeting of vinpocetine-derived ionizable-lipidoid nanoparticles
inferred← citeshttps://doi.org/10.1038/s41598-023-49939-9openalex-snapshot
Novel betulin derivatives as multidrug reversal agents targeting P-glycoprotein
inferred← citeshttps://doi.org/10.1038/s41598-026-55249-7openalex-snapshot
In-silico study of the bioactive compounds of Blighia sapida koenig revealed a novel Plasmodium falciparum dihydroorotate dehydrogenase inhibitor for malaria
inferred← citeshttps://doi.org/10.1039/d0ob00078gopenalex-snapshot
A modular approach to the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine
inferred← citeshttps://doi.org/10.1039/d6md00580bopenalex-snapshot
Tryptoline urea derivatives for sensitizing resistant breast cancer cells to doxorubicin
inferred← citeshttps://doi.org/10.1080/00498254.2020.1857467openalex-snapshot
Effects of breviscapine and C3435T MDR1 gene polymorphism on the pharmacokinetics of fexofenadine, a P-glycoprotein substrate, in healthy volunteers
inferred← citeshttps://doi.org/10.1080/01635581.2018.1560480openalex-snapshot
MIX2: A Novel Natural Multi-Component Modulator of Multidrug-Resistance and Hallmarks of Cancer Cells
inferred← citeshttps://doi.org/10.1080/10408398.2024.2387320openalex-snapshot
Intestinal absorption mechanism and nutritional synergy promotion strategy of dietary flavonoids: transintestinal epithelial pathway mediated by intestinal transport proteins
inferred← citeshttps://doi.org/10.1080/1061186x.2022.2069782openalex-snapshot
Nanocarrier-based co-delivery approaches of chemotherapeutics with natural P-glycoprotein inhibitors in the improvement of multidrug resistance cancer therapy
inferred← citeshttps://doi.org/10.1080/1061186x.2022.2091578openalex-snapshot
ABC transporters in breast cancer: their roles in multidrug resistance and beyond
inferred← citeshttps://doi.org/10.1080/1061186x.2024.2356751openalex-snapshot
Comprehensive insights into herbal P-glycoprotein inhibitors and nanoformulations for improving anti-retroviral therapy efficacy
inferred← citeshttps://doi.org/10.1080/10717544.2018.1469686openalex-snapshot
Sericin nanomicelles with enhanced cellular uptake and pH-triggered release of doxorubicin reverse cancer drug resistance
inferred← citeshttps://doi.org/10.1080/10837450.2019.1683749openalex-snapshot
Enhanced oral bioavailability of valsartan in rats using a supersaturable self-microemulsifying drug delivery system with P-glycoprotein inhibitors
inferred← citeshttps://doi.org/10.1080/14786419.2017.1402323openalex-snapshot
Ethyl lucidenates A reverses P-glycoprotein mediated vincristine resistance in K562/A02 cells
inferred← citeshttps://doi.org/10.1080/14786419.2024.2420333openalex-snapshot
Identification of flavonol derivatives inhibiting MDR1: a strategy to overcome multidrug resistance in cancer
inferred← citeshttps://doi.org/10.1080/14786419.2025.2472276openalex-snapshot
A new withanolide from Saponaria officinalis and its antimicrobial and cytotoxic activities
inferred← citeshttps://doi.org/10.1080/17425255.2020.1701653openalex-snapshot
Modulation of expression/function of intestinal P-glycoprotein under disease states
inferred← citeshttps://doi.org/10.1088/1742-6596/1912/1/012047openalex-snapshot
A systematic literature review (SLR): evaluation pharmacokinetic profile of drug combined p-glycoprotein (p-gp) alkaloid inhibitor in white rats (rattus norvegicus)
inferred← citeshttps://doi.org/10.1101/2023.05.26.542404openalex-snapshot
Network Pharmacology and molecular docking approach to unveil the mechanism of Hypericum perforatum in the management of Alzheimer’s disorder
inferred← citeshttps://doi.org/10.1111/cns.14528openalex-snapshot
Self‐Assembled nanoparticles of natural bioactive molecules enhance the delivery and efficacy of paclitaxel in glioblastoma
inferred← citeshttps://doi.org/10.1142/s0192415x26500643openalex-snapshot
Berberine from Traditional Chinese Medicine in Liver Diseases: From Steatosis to Fibrosis and Hepatic Malignancies
inferred← citeshttps://doi.org/10.1152/ajpcell.00412.2025openalex-snapshot
Strategies for overcoming ABC transporter-mediated multidrug resistance in colorectal cancer
inferred← citeshttps://doi.org/10.1155/2019/1279036openalex-snapshot
Administration of Vitamin D Metabolites Affects RNA Expression of Xenobiotic Metabolising Enzymes and Function of ABC Transporters in Rats
inferred← citeshttps://doi.org/10.1177/09603271211008496openalex-snapshot
Attenuation of diethyl nitrosamine-induced hepatocellular carcinoma by taxifolin and/or alogliptin: The interplay between toll-like receptor 4, transforming growth factor beta-1, and apoptosis
inferred← citeshttps://doi.org/10.1177/15347354211061720openalex-snapshot
Traditional Chinese Medicine Therapy for Esophageal Cancer: A Literature Review
inferred← citeshttps://doi.org/10.1177/15347354221077682openalex-snapshot
Borneol and Tetrandrine Modulate the Blood–Brain Barrier and Blood–Tumor Barrier to Improve the Therapeutic Efficacy of 5-Fluorouracil in Brain Metastasis
inferred← citeshttps://doi.org/10.1177/15347354221090221openalex-snapshot
Polysaccharides Produced by the Mushroom Trametes robiniophila Murr Boosts the Sensitivity of Hepatoma Cells to Oxaliplatin via the miR-224-5p/ABCB1/P-gp Axis
inferred← citeshttps://doi.org/10.1186/s11658-022-00362-4openalex-snapshot
d-Borneol enhances cisplatin sensitivity via p21/p27-mediated S-phase arrest and cell apoptosis in non-small cell lung cancer cells and a murine xenograft model
inferred← citeshttps://doi.org/10.1186/s12943-022-01668-9openalex-snapshot
Antioxidants in brain tumors: current therapeutic significance and future prospects
inferred← citeshttps://doi.org/10.1186/s12943-022-01712-8openalex-snapshot
CAR T cells: engineered immune cells to treat brain cancers and beyond
inferred← citeshttps://doi.org/10.1186/s12951-022-01626-zopenalex-snapshot
Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer
inferred← citeshttps://doi.org/10.1186/s13020-022-00647-yopenalex-snapshot
The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters
inferred← citeshttps://doi.org/10.1186/s13046-018-0967-0openalex-snapshot
Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer
inferred← citeshttps://doi.org/10.1186/s13287-026-05094-2openalex-snapshot
Mapping the evolutionary landscape of intestinal organoids: from self-organization biology to precision medicine
inferred← citeshttps://doi.org/10.1186/s43094-021-00252-0openalex-snapshot
Synthesis, characterization, and pharmacological evaluation of some metal complexes of quercetin as P-gp inhibitors
inferred← citeshttps://doi.org/10.1208/s12249-024-02765-2openalex-snapshot
Recent Trends in Nanocarrier-Based Drug Delivery System for Prostate Cancer
inferred← citeshttps://doi.org/10.14232/phd.11230openalex-snapshot
Efflux pump inhibitors and potential adjuvants to reverse multidrug resistance in bacteria and tumor cells
inferred← citeshttps://doi.org/10.14715/cmb/2019.65.1.14openalex-snapshot
Schizandrol A reverses multidrug resistance in resistant chronic myeloid leukemia cells K562/A02
inferred← citeshttps://doi.org/10.1515/hmbci-2025-0016openalex-snapshot
An overview of the relationship between melatonin and drug resistance in cancers
inferred← citeshttps://doi.org/10.1515/tsd-2025-2709openalex-snapshot
Targeting P-glycoprotein-mediated drug resistance: in silico screening and in vitro evaluation of phytochemicals
inferred← citeshttps://doi.org/10.21203/rs.3.rs-6732407/v1openalex-snapshot
Development, characterization and optimization of Berberine and Curcumin loaded PCL- Chitosan nanoparticles by electrospraying for cancer drug delivery
inferred← citeshttps://doi.org/10.2147/dddt.s207224openalex-snapshot
Novel peptide myristoly-CM4 induces selective cytotoxicity in leukemia K562/MDR and Jurkat cells by necrosis and/or apoptosis pathway
inferred← citeshttps://doi.org/10.2174/0109298673319832240829164046openalex-snapshot
A Molecular Dynamic Simulation, Structural Analysis, and Ex Vivo Insights into the P-glycoprotein Mediated Interactions of Dietary Polyphenols with Cyclin-dependent Kinase Inhibitors: A Potential Strategy to Counteract Drug Efflux
inferred← citeshttps://doi.org/10.2174/0113816128282248231205105408openalex-snapshot
Nano Strategies for Artemisinin Derivatives to Enhance Reverse Efficiency of Multidrug Resistance in Breast Cancer
inferred← citeshttps://doi.org/10.2174/1389557521666210913112733openalex-snapshot
Anticancer Potential of Naringenin, Biosynthesis, Molecular Target, and Structural Perspectives
inferred← citeshttps://doi.org/10.2174/1874467213666200525010624openalex-snapshot
Recent Advances in Herbal Nanomedicines for Cancer Treatment
inferred← citeshttps://doi.org/10.2217/nnm-2017-0354openalex-snapshot
Self-Emulsifying Drug–Delivery Systems Modulate P-Glycoprotein Activity: Role of Excipients and Formulation Aspects
inferred← citeshttps://doi.org/10.2217/pgs-2021-0116openalex-snapshot
ATP Binding Cassette Transporters and Cancer: Revisiting Their Controversial Role
inferred← citeshttps://doi.org/10.2460/ajvr.23.09.0210openalex-snapshot
Inhibitor of P-glycoprotein–mediated drug transport by curcumin in broiler chickens
inferred← citeshttps://doi.org/10.33612/diss.178482741openalex-snapshot
Monitoring the Function of the P-glycoprotein Transporter at the Blood Brain Barrier
inferred← citeshttps://doi.org/10.3389/fddsv.2024.1363364openalex-snapshot
A review on dynamics of permeability-glycoprotein in efflux of chemotherapeutic drugs
inferred← citeshttps://doi.org/10.3389/fmicb.2024.1455759openalex-snapshot
Prevention and potential remedies for antibiotic resistance: current research and future prospects
inferred← citeshttps://doi.org/10.3389/fonc.2026.1913688openalex-snapshot
Targeted phytotherapy: essential oils, multi-target cancer action & nanodelivery
inferred← citeshttps://doi.org/10.3389/fphar.2019.00746openalex-snapshot
Anti-Cancer Effects of Pristimerin and the Mechanisms: A Critical Review
inferred← citeshttps://doi.org/10.3389/fphar.2021.720474openalex-snapshot
Emerging Significance of Ginsenosides as Potentially Reversal Agents of Chemoresistance in Cancer Therapy
inferred← citeshttps://doi.org/10.3389/fphar.2021.796745openalex-snapshot
Involvement of P-gp on Reversing Multidrug Resistance Effects of 23-Hydroxybetulinic Acid on Chemotherapeutic Agents
inferred← citeshttps://doi.org/10.3389/fphar.2022.867133openalex-snapshot
Metformin and Thymoquinone Synergistically Inhibit Proliferation of Imatinib-Resistant Human Leukemic Cells
inferred← citeshttps://doi.org/10.3389/fphar.2026.1854397openalex-snapshot
Extracts from Eryngium heterophyllum Engelm. [Apiaceae] enhance paclitaxel cytotoxicity in A549 lung cancer cells
inferred← citeshttps://doi.org/10.3389/fvets.2020.601750openalex-snapshot
Plant-Derived Compounds as a Tool for the Control of Gastrointestinal Nematodes: Modulation of Abamectin Pharmacological Action by Carvone
inferred← citeshttps://doi.org/10.3390/antiox7010010openalex-snapshot
Long-Chain Metabolites of Vitamin E: Metabolic Activation as a General Concept for Lipid-Soluble Vitamins?
inferred← citeshttps://doi.org/10.3390/antiox9050455openalex-snapshot
Multidrug Resistance Modulation Activity of Silybin Derivatives and Their Anti-Inflammatory Potential
inferred← citeshttps://doi.org/10.3390/app11125532openalex-snapshot
Phytoglycoproteins and Human Health: Current Knowledge and Future Applications
inferred← citeshttps://doi.org/10.3390/app15158350openalex-snapshot
Insight into the in Silico Structural, Physicochemical, Pharmacokinetic and Toxicological Properties of Antibacterially Active Viniferins and Viniferin-Based Compounds as Derivatives of Resveratrol Containing a (2,3-Dihydro)benzo[b]furan Privileged Scaffold
inferred← citeshttps://doi.org/10.3390/app15168772openalex-snapshot
In Silico Identification of Six Mushroom-Derived Sterol and Triterpenoid Compounds as Potential P-Glycoprotein Modulators in Multidrug Resistance
inferred← citeshttps://doi.org/10.3390/biologics4040027openalex-snapshot
Antimicrobial Peptides from Frogs of the Glandirana Genus
inferred← citeshttps://doi.org/10.3390/biology12030415openalex-snapshot
The Molecular Mechanisms of Oleanane Aldehyde-β-enone Cytotoxicity against Doxorubicin-Resistant Cancer Cells
inferred← citeshttps://doi.org/10.3390/cells10020458openalex-snapshot
Ellagic Acid and Schisandrins: Natural Biaryl Polyphenols with Therapeutic Potential to Overcome Multidrug Resistance in Cancer
inferred← citeshttps://doi.org/10.3390/futurepharmacol5010005openalex-snapshot
An Overview of Sargassum Seaweed as Natural Anticancer Therapy
inferred← citeshttps://doi.org/10.3390/gels11040294openalex-snapshot
Unlocking the Rich Potential of a Soft Gel-Cream Enriched with Royal Jelly for Topical Use
inferred← citeshttps://doi.org/10.3390/ijms21020633openalex-snapshot
Potentiation of Low-Dose Doxorubicin Cytotoxicity by Affecting P-Glycoprotein through Caryophyllane Sesquiterpenes in HepG2 Cells: an in Vitro and in Silico Study
inferred← citeshttps://doi.org/10.3390/ijms21165622openalex-snapshot
Anticancer Potential of Furanocoumarins: Mechanistic and Therapeutic Aspects
inferred← citeshttps://doi.org/10.3390/ijms24044140openalex-snapshot
Natural Inhibitors of P-glycoprotein in Acute Myeloid Leukemia
inferred← citeshttps://doi.org/10.3390/ijms24065964openalex-snapshot
Chalcones and Gastrointestinal Cancers: Experimental Evidence
inferred← citeshttps://doi.org/10.3390/ijms241713089openalex-snapshot
Changes in Expression and Function of Placental and Intestinal P-gp and BCRP Transporters during Pregnancy
inferred← citeshttps://doi.org/10.3390/ijms252111346openalex-snapshot
A BPTF Inhibitor That Interferes with the Multidrug Resistance Pump to Sensitize Murine Triple-Negative Breast Cancer Cells to Chemotherapy
inferred← citeshttps://doi.org/10.3390/ijms26051860openalex-snapshot
Predictions of the Biological Effects of the Main Components of Tarragon Essential Oil
inferred← citeshttps://doi.org/10.3390/ijms26136208openalex-snapshot
Isorhamnetin Modulates Drug-Resistance-Related Biomarkers in Colon Cancer Cells
inferred← citeshttps://doi.org/10.3390/ijms26146976openalex-snapshot
Alterations in P-glycoprotein Expression in the Placenta of Obese Rats and Humans
inferred← citeshttps://doi.org/10.3390/ijms262411912openalex-snapshot
Soloxolone N-3-(Dimethylamino)propylamide Suppresses Tumor Growth and Mitigates Doxorubicin-Induced Hepatotoxicity in RLS40 Lymphosarcoma-Bearing Mice
inferred← citeshttps://doi.org/10.3390/membranes13060568openalex-snapshot
The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs
inferred← citeshttps://doi.org/10.3390/molecules24091824openalex-snapshot
The Effect of Furanocoumarin Derivatives on Induction of Apoptosis and Multidrug Resistance in Human Leukemic Cells
inferred← citeshttps://doi.org/10.3390/molecules24132505openalex-snapshot
Similar Safety Profile of the Enantiomeric N-Aminoalkyl Derivatives of Trans-2-Aminocyclohexan-1-ol Demonstrating Anticonvulsant Activity
inferred← citeshttps://doi.org/10.3390/molecules26113121openalex-snapshot
Synthesis and Characterization of Some New Quinoxalin-2(1H)one and 2-Methyl-3H-quinazolin-4-one Derivatives Targeting the Onset and Progression of CRC with SAR, Molecular Docking, and ADMET Analyses
inferred← citeshttps://doi.org/10.3390/molecules27030616openalex-snapshot
Multidrug Resistance (MDR): A Widespread Phenomenon in Pharmacological Therapies
inferred← citeshttps://doi.org/10.3390/molecules27238556openalex-snapshot
In Vitro Evaluation of the Interaction of Seven Biologically Active Components in Anemarrhenae rhizoma with P-gp
inferred← citeshttps://doi.org/10.3390/molecules28145500openalex-snapshot
The Potential Role of Timosaponin-AIII in Cancer Prevention and Treatment
inferred← citeshttps://doi.org/10.3390/molecules28165936openalex-snapshot
Machine Learning Techniques Applied to the Study of Drug Transporters
inferred← citeshttps://doi.org/10.3390/molecules29030713openalex-snapshot
Bergaptol, a Major Furocoumarin in Citrus: Pharmacological Properties and Toxicity
inferred← citeshttps://doi.org/10.3390/molecules29204939openalex-snapshot
Soloxolone N-3-(Dimethylamino)propylamide Restores Drug Sensitivity of Tumor Cells with Multidrug-Resistant Phenotype via Inhibition of P-Glycoprotein Efflux Function
inferred← citeshttps://doi.org/10.3390/molecules30030652openalex-snapshot
Towards Improved Bioavailability of Cereal Inositol Phosphates, Myo-Inositol and Phenolic Acids
inferred← citeshttps://doi.org/10.3390/molecules30071561openalex-snapshot
Plant Alkaloids as Promising Anticancer Compounds with Blood–Brain Barrier Penetration in the Treatment of Glioblastoma: In Vitro and In Vivo Models
inferred← citeshttps://doi.org/10.3390/molecules30092033openalex-snapshot
Novel Crown Ether-Functionalized Fusidic Acid Butyl Ester: Synthesis, Biological Evaluation, In Silico ADMET, and Molecular Docking Studies
inferred← citeshttps://doi.org/10.3390/nu15051118openalex-snapshot
Non-Nutritive Sweeteners Acesulfame Potassium and Sucralose Are Competitive Inhibitors of the Human P-glycoprotein/Multidrug Resistance Protein 1 (PGP/MDR1)
inferred← citeshttps://doi.org/10.3390/ph14020111openalex-snapshot
RETRACTED: In Vitro Modulation of P-Glycoprotein Activity by Euphorbia intisy Essential Oil on Acute Myeloid Leukemia Cell Line HL-60R
inferred← citeshttps://doi.org/10.3390/ph15030356openalex-snapshot
Phytol and Heptacosane Are Possible Tools to Overcome Multidrug Resistance in an In Vitro Model of Acute Myeloid Leukemia
inferred← citeshttps://doi.org/10.3390/ph15040395openalex-snapshot
Natural Phaeosphaeride A Derivatives Overcome Drug Resistance of Tumor Cells and Modulate Signaling Pathways
inferred← citeshttps://doi.org/10.3390/ph17050578openalex-snapshot
Anticancer Potential and Molecular Targets of Pristimerin in Human Malignancies
inferred← citeshttps://doi.org/10.3390/ph17070911openalex-snapshot
Aronia Berry Extract Modulates MYD88/NF-kB/P-Glycoprotein Axis to Overcome Gemcitabine Resistance in Pancreatic Cancer
inferred← citeshttps://doi.org/10.3390/pharmaceutics13010124openalex-snapshot
Potential Herb–Drug Interactions in the Management of Age-Related Cognitive Dysfunction
inferred← citeshttps://doi.org/10.3390/pharmaceutics13071103openalex-snapshot
Pharmaceutical Formulations with P-Glycoprotein Inhibitory Effect as Promising Approaches for Enhancing Oral Drug Absorption and Bioavailability
inferred← citeshttps://doi.org/10.3390/pharmaceutics15071942openalex-snapshot
Coleon U, Isolated from Plectranthus mutabilis Codd., Decreases P-Glycoprotein Activity Due to Mitochondrial Inhibition
inferred← citeshttps://doi.org/10.3390/pharmaceutics15112567openalex-snapshot
Characterization and Pharmacokinetic Assessment of a New Berberine Formulation with Enhanced Absorption In Vitro and in Human Volunteers
inferred← citeshttps://doi.org/10.3390/pharmaceutics17091208openalex-snapshot
Formulation and Comparative Characterization of SLNs and NLCs for Targeted Co-Delivery of Paclitaxel and Hydroxytyrosol Carboxylic Acid Esters Against Triple-Negative Breast Cancer
inferred← citeshttps://doi.org/10.3390/scipharm86040043openalex-snapshot
Pharmacokinetic Enhancers (Boosters)—Escort for Drugs against Degrading Enzymes and Beyond
inferred← citeshttps://doi.org/10.34172/apb.2020.058openalex-snapshot
Kaempferol-Mediated Sensitization Enhances Chemotherapeutic Efficacy of Sorafenib Against Hepatocellular Carcinoma: An In Silico and In Vitro Approach
inferred← citeshttps://doi.org/10.34172/jhp.2023.26openalex-snapshot
Co-administration of herbal inhibitors of P-glycoprotein with renal drugs enhance their bioavailability– In silico approach
inferred← citeshttps://doi.org/10.3892/br.2024.1907openalex-snapshot
Herbal drug‑based nanotherapy for hepatocellular carcinoma: Quercetin‑contained nanocarrier as a multipurpose therapeutic agent against hepatocellular carcinoma (Review)
inferred← citeshttps://doi.org/10.4155/fmc-2023-0161openalex-snapshot
Pharmacokinetic Correlation of Structurally Modified Chalcone Derivatives As Promising Leads to Treat Tuberculosis
inferred← citeshttps://doi.org/10.52417/njls.v12i2.355openalex-snapshot
Comparative Study on the Phytometabolites, in vitro Antiplasmodial Activity and Cytotoxicity of Stem Bark Extracts of Annickia affinis (Exell) Versteegh & Sosef and Annickia chlorantha (Oliv.) Setten & PJ. Mass
inferred← citeshttps://doi.org/10.52667/2712-9179-2024-4-3-37-44openalex-snapshot
Frequency of "Poor Transporter" Phenotype Among Patients with Mental Disorders: Pilot Study
inferred← citeshttps://doi.org/10.54844/cai.2022.0077openalex-snapshot
New Hope in Microbial Multidrug Resistance
inferred← citeshttps://doi.org/10.5603/pmpi.2018.0011openalex-snapshot
The role of metabolites in morphine analgesic effects
inferred← citeshttps://doi.org/10.5772/intechopen.88412openalex-snapshot
Self-Emulsifying Drug Delivery Systems: Easy to Prepare Multifunctional Vectors for Efficient Oral Delivery
inferred← citeshttps://doi.org/10.5772/intechopen.95553openalex-snapshot
Overcoming P-Glycoprotein-Mediated Doxorubicin Resistance
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